| 1 |
Mapoly0027s0185
| [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF39] CDC2-RELATED PROTEIN KINASE; [KOG0600] Cdc2-related protein kinase; [K08819] Cdc2-related kinase, arginine/serine-rich [EC:2.7.11.22]; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE | 1.73 | 0.8366 |
| 2 |
Mapoly0086s0067
| [GO:0005524] ATP binding; [GO:0032300] mismatch repair complex; [KOG1979] DNA mismatch repair protein - MLH1 family; [PTHR10073] DNA MISMATCH REPAIR PROTEIN (MLH, PMS, MUTL); [PTHR10073:SF12] DNA MISMATCH REPAIR PROTEIN MUTL; [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [K08734] DNA mismatch repair protein MLH1; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01119] DNA mismatch repair protein, C-terminal domain | 4.36 | 0.7635 |
| 3 |
Mapoly0097s0045
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11752] HELICASE SKI2W; [2.7.7.7] DNA-directed DNA polymerase.; [K02349] DNA polymerase theta subunit [EC:2.7.7.7]; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF00476] DNA polymerase family A; [GO:0003676] nucleic acid binding; [GO:0003887] DNA-directed DNA polymerase activity; [KOG0950] DNA polymerase theta/eta, DEAD-box superfamily | 5.66 | 0.7971 |
| 4 |
Mapoly0080s0034
| [2.1.1.43] Histone-lysine N-methyltransferase.; [KOG1082] Histone H3 (Lys9) methyltransferase SUV39H1/Clr4, required for transcriptional silencing; [K11419] histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43]; [PF05033] Pre-SET motif; [GO:0005515] protein binding; [PF00856] SET domain; [GO:0008270] zinc ion binding; [GO:0018024] histone-lysine N-methyltransferase activity; [PTHR22884] SET DOMAIN PROTEINS; [GO:0005634] nucleus; [GO:0034968] histone lysine methylation; [PF13771] PHD-like zinc-binding domain | 7.35 | 0.7972 |
| 5 |
Mapoly0034s0011
| [PF09133] SANTA (SANT Associated) | 9.70 | 0.7985 |
| 6 |
Mapoly0011s0164
| [GO:0005524] ATP binding; [PTHR24223:SF5] SUBFAMILY NOT NAMED; [GO:0016021] integral to membrane; [PTHR24223] FAMILY NOT NAMED; [PF00664] ABC transporter transmembrane region; [GO:0016887] ATPase activity; [GO:0006810] transport; [GO:0055085] transmembrane transport; [KOG0054] Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily; [GO:0042626] ATPase activity, coupled to transmembrane movement of substances; [PF00005] ABC transporter | 10.54 | 0.6928 |
| 7 |
Mapoly0131s0025
| [PF08324] PUL domain; [KOG0301] Phospholipase A2-activating protein (contains WD40 repeats); [PTHR19849] PHOSPHOLIPASE A-2-ACTIVATING PROTEIN; [PTHR19849:SF0] SUBFAMILY NOT NAMED; [K14018] phospholipase A-2-activating protein; [GO:0005515] protein binding; [PF09070] PFU (PLAA family ubiquitin binding); [PF00400] WD domain, G-beta repeat | 11.83 | 0.7478 |
| 8 |
Mapoly0005s0161
| [GO:0003677] DNA binding; [PTHR13451:SF0] SUBFAMILY NOT NAMED; [3.1.22.-] Endodeoxyribonucleases producing other than 5'-phosphomonoesters.; [K08991] crossover junction endonuclease MUS81 [EC:3.1.22.-]; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PF02732] ERCC4 domain | 12.41 | 0.7702 |
| 9 |
Mapoly0023s0117
| [PTHR10139] DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11A; [PF04152] Mre11 DNA-binding presumed domain; [KOG2310] DNA repair exonuclease MRE11; [GO:0006259] DNA metabolic process; [PF00149] Calcineurin-like phosphoesterase; [GO:0006302] double-strand break repair; [GO:0016787] hydrolase activity; [GO:0030145] manganese ion binding; [GO:0005634] nucleus; [GO:0004527] exonuclease activity; [K10865] double-strand break repair protein MRE11; [GO:0004519] endonuclease activity | 15.30 | 0.7783 |
| 10 |
Mapoly0055s0120
| - | 15.68 | 0.7899 |
| 11 |
Mapoly0050s0101
| [3.4.21.48] Cerevisin.; [K01336] cerevisin [EC:3.4.21.48]; [GO:0004252] serine-type endopeptidase activity; [PF00082] Subtilase family; [PF00090] Thrombospondin type 1 domain; [PF00053] Laminin EGF-like (Domains III and V); [GO:0006508] proteolysis; [PTHR10795] PROPROTEIN CONVERTASE SUBTILISIN/KEXIN | 16.91 | 0.7609 |
| 12 |
Mapoly0226s0007
| [PF00817] impB/mucB/samB family; [2.7.7.7] DNA-directed DNA polymerase.; [GO:0006281] DNA repair; [PF11799] impB/mucB/samB family C-terminal domain; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [PTHR11076:SF11] DNA POLYMERASE ETA; [GO:0003887] DNA-directed DNA polymerase activity; [GO:0003684] damaged DNA binding; [K03509] DNA polymerase eta subunit [EC:2.7.7.7] | 18.89 | 0.7275 |
| 13 |
Mapoly0034s0031
| [GO:0007094] mitotic spindle assembly checkpoint; [K06638] mitotic spindle assembly checkpoint protein MAD1; [KOG4593] Mitotic checkpoint protein MAD1; [PTHR23168] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 (MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1); [PF05557] Mitotic checkpoint protein; [PTHR23168:SF0] SUBFAMILY NOT NAMED | 19.36 | 0.7910 |
| 14 |
Mapoly0016s0079
| [GO:0005524] ATP binding; [KOG2680] DNA helicase TIP49, TBP-interacting protein; [3.6.4.12] DNA helicase.; [PF06068] TIP49 C-terminus; [GO:0043141] ATP-dependent 5'-3' DNA helicase activity; [K11338] RuvB-like protein 2 [EC:3.6.4.12]; [GO:0003678] DNA helicase activity; [PTHR11093] RUVB-RELATED REPTIN AND PONTIN; [PTHR11093:SF2] RUVB-LIKE 2 (REPTIN) | 19.42 | 0.7715 |
| 15 |
Mapoly0007s0101
| [PF09728] Myosin-like coiled-coil protein; [KOG1850] Myosin-like coiled-coil protein; [PTHR16127] TAXILIN; [GO:0019905] syntaxin binding | 20.57 | 0.7328 |
| 16 |
Mapoly0023s0072
| [3.1.27.-] Endoribonucleases producing other than 5'-phosphomonoesters.; [K13148] integrator complex subunit 11 [EC:3.1.27.-]; [PF07521] RNA-metabolising metallo-beta-lactamase; [PTHR11203] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF00753] Metallo-beta-lactamase superfamily; [PTHR11203:SF11] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF10996] Beta-Casp domain; [KOG1136] Predicted cleavage and polyadenylation specificity factor (CPSF subunit) | 25.46 | 0.7511 |
| 17 |
Mapoly0001s0472
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED | 25.51 | 0.7824 |
| 18 |
Mapoly0104s0010
| [PTHR17204:SF5] PRE-MRNA PROCESSING PROTEIN PRP39-RELATED; [K13217] pre-mRNA-processing factor 39; [KOG1258] mRNA processing protein; [GO:0006397] mRNA processing; [GO:0005634] nucleus; [PF05843] Suppressor of forked protein (Suf); [PTHR17204] PRE-MRNA PROCESSING PROTEIN PRP39-RELATED | 25.81 | 0.7636 |
| 19 |
Mapoly0005s0093
| [KOG1883] Cofactor required for Sp1 transcriptional activation, subunit 3; [PF11573] Mediator complex subunit 23; [PTHR12691] FAMILY NOT NAMED | 26.72 | 0.7614 |
| 20 |
Mapoly0042s0123
| [K12875] apoptotic chromatin condensation inducer in the nucleus; [GO:0003676] nucleic acid binding; [PTHR14127] APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; [PF02037] SAP domain | 28.71 | 0.7787 |
| 21 |
Mapoly0004s0128
| [GO:0005524] ATP binding; [K08864] tousled-like kinase [EC:2.7.11.1]; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PTHR22974] MIXED LINEAGE PROTEIN KINASE; [KOG1151] Tousled-like protein kinase | 28.86 | 0.7643 |
| 22 |
Mapoly0042s0086
| [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K08737] DNA mismatch repair protein MSH6; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PTHR11361:SF31] MUTS HOMOLOG 6, MSH6; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV | 29.50 | 0.7691 |
| 23 |
Mapoly0004s0169
| [GO:0003677] DNA binding; [GO:0006338] chromatin remodeling; [GO:0005524] ATP binding; [PF09110] HAND; [K11654] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]; [GO:0043044] ATP-dependent chromatin remodeling; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [GO:0005634] nucleus; [PTHR10799:SF73] ISWI CHROMATIN-REMODELING COMPLEX ATPASE ISW1; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [KOG0385] Chromatin remodeling complex WSTF-ISWI, small subunit; [GO:0003676] nucleic acid binding; [GO:0031491] nucleosome binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [PF09111] SLIDE | 31.46 | 0.7747 |
| 24 |
Mapoly0187s0003
| [PTHR22880] FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; [K06062] histone acetyltransferase [EC:2.3.1.48]; [GO:0005515] protein binding; [PF00439] Bromodomain; [GO:0008080] N-acetyltransferase activity; [PF00583] Acetyltransferase (GNAT) family; [2.3.1.48] Histone acetyltransferase. | 33.94 | 0.7444 |
| 25 |
Mapoly0122s0062
| [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 | 36.06 | 0.7749 |
| 26 |
Mapoly0007s0066
| [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PTHR19306:SF1] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5 SMC5; [KOG0979] Structural maintenance of chromosome protein SMC5/Spr18, SMC superfamily; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0000724] double-strand break repair via homologous recombination | 36.88 | 0.7672 |
| 27 |
Mapoly0015s0073
| [PF12780] P-loop containing dynein motor region D4; [PF12774] Hydrolytic ATP binding site of dynein motor region D1; [PF12775] P-loop containing dynein motor region D3; [GO:0005858] axonemal dynein complex; [GO:0030286] dynein complex; [PTHR10676] DYNEIN HEAVY CHAIN FAMILY PROTEIN; [PF03028] Dynein heavy chain and region D6 of dynein motor; [GO:0016887] ATPase activity; [KOG3595] Dyneins, heavy chain; [PF12777] Microtubule-binding stalk of dynein motor; [GO:0007018] microtubule-based movement; [PF08393] Dynein heavy chain, N-terminal region 2; [PF12781] ATP-binding dynein motor region D5; [GO:0003341] cilium movement; [PTHR10676:SF138] DYNEIN HEAVY CHAIN FAMILY PROTEIN; [GO:0003777] microtubule motor activity | 37.83 | 0.7261 |
| 28 |
Mapoly0113s0020
| [GO:0003677] DNA binding; [PTHR12604:SF2] KU P70 DNA HELICASE; [K10884] ATP-dependent DNA helicase 2 subunit 1; [GO:0042162] telomeric DNA binding; [PF03730] Ku70/Ku80 C-terminal arm; [PF02735] Ku70/Ku80 beta-barrel domain; [PF03731] Ku70/Ku80 N-terminal alpha/beta domain; [GO:0043564] Ku70:Ku80 complex; [GO:0005634] nucleus; [GO:0004003] ATP-dependent DNA helicase activity; [GO:0003676] nucleic acid binding; [KOG2327] DNA-binding subunit of a DNA-dependent protein kinase (Ku70 autoantigen); [PTHR12604] KU AUTOANTIGEN DNA HELICASE; [GO:0003684] damaged DNA binding; [GO:0006303] double-strand break repair via nonhomologous end joining; [PF02037] SAP domain; [GO:0000723] telomere maintenance | 38.37 | 0.7181 |
| 29 |
Mapoly0001s0420
| [PTHR16212:SF4] SUBFAMILY NOT NAMED; [PF12530] Protein of unknown function (DUF3730); [PTHR16212] FAMILY NOT NAMED | 39.23 | 0.7222 |
| 30 |
Mapoly0001s0391
| [GO:0005634] nucleus; [PF05965] F/Y rich C-terminus | 42.19 | 0.7620 |
| 31 |
Mapoly0003s0057
| [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination | 43.27 | 0.7731 |
| 32 |
Mapoly0045s0049
| - | 43.84 | 0.7188 |
| 33 |
Mapoly0009s0067
| [PTHR31789] FAMILY NOT NAMED | 45.44 | 0.7426 |
| 34 |
Mapoly0005s0045
| [PF15628] RRM in Demeter; [PTHR10359] A/G-SPECIFIC ADENINE GLYCOSYLASE/ENDONUCLEASE III | 45.55 | 0.7548 |
| 35 |
Mapoly0024s0018
| [PTHR23147] SERINE/ARGININE RICH SPLICING FACTOR; [KOG4207] Predicted splicing factor, SR protein superfamily; [K12891] splicing factor, arginine/serine-rich 2; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 46.73 | 0.7375 |
| 36 |
Mapoly0165s0024
| [GO:0006338] chromatin remodeling; [GO:0043968] histone H2A acetylation; [PF00249] Myb-like DNA-binding domain; [K11324] DNA methyltransferase 1-associated protein 1; [GO:0043967] histone H4 acetylation; [KOG2656] DNA methyltransferase 1-associated protein-1; [GO:0003682] chromatin binding; [PTHR12855] FAMILY NOT NAMED; [GO:0035267] NuA4 histone acetyltransferase complex; [GO:0006281] DNA repair; [PTHR12855:SF10] SUBFAMILY NOT NAMED | 47.56 | 0.7473 |
| 37 |
Mapoly0013s0109
| [PF00514] Armadillo/beta-catenin-like repeat; [PF00651] BTB/POZ domain; [GO:0005515] protein binding; [KOG0166] Karyopherin (importin) alpha; [PTHR23315] BETA CATENIN-RELATED ARMADILLO REPEAT-CONTAINING | 48.00 | 0.7425 |
| 38 |
Mapoly0097s0033
| [PTHR10870] CELL CYCLE CHECKPOINT PROTEIN RAD1; [KOG3194] Checkpoint 9-1-1 complex, RAD1 component; [PF02144] Repair protein Rad1/Rec1/Rad17; [GO:0005634] nucleus; [K02830] cell cycle checkpoint protein [EC:3.1.11.2]; [GO:0006281] DNA repair; [3.1.11.2] Exodeoxyribonuclease III. | 51.38 | 0.7059 |
| 39 |
Mapoly0072s0079
| [PF11717] RNA binding activity-knot of a chromodomain; [K11339] mortality factor 4-like protein 1; [GO:0005634] nucleus; [PTHR10880] MORTALITY FACTOR 4-LIKE PROTEIN; [PF05712] MRG | 52.99 | 0.7584 |
| 40 |
Mapoly0048s0100
| [PTHR18937:SF8] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC3; [GO:0005524] ATP binding; [KOG0964] Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3); [GO:0008280] cohesin core heterodimer; [GO:0005515] protein binding; [GO:0003682] chromatin binding; [GO:0007064] mitotic sister chromatid cohesion; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain; [K06669] structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) | 56.39 | 0.7463 |
| 41 |
Mapoly0151s0042
| [PTHR31500:SF0] SUBFAMILY NOT NAMED; [PF03479] Domain of unknown function (DUF296); [PTHR31500] FAMILY NOT NAMED | 57.45 | 0.7230 |
| 42 |
Mapoly0105s0060
| [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [K12898] heterogeneous nuclear ribonucleoprotein F/H; [KOG4211] Splicing factor hnRNP-F and related RNA-binding proteins; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED | 57.75 | 0.7586 |
| 43 |
Mapoly0029s0003
| [KOG1824] TATA-binding protein-interacting protein; [PTHR12696] TIP120; [PF08623] TATA-binding protein interacting (TIP20); [PF13646] HEAT repeats | 58.30 | 0.7432 |
| 44 |
Mapoly0099s0053
| [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding | 58.65 | 0.7386 |
| 45 |
Mapoly0005s0061
| [PF00089] Trypsin; [PTHR22939] SERINE PROTEASE FAMILY S1C HTRA-RELATED; [GO:0005515] protein binding; [PF13180] PDZ domain; [KOG1320] Serine protease; [GO:0004252] serine-type endopeptidase activity; [GO:0006508] proteolysis | 58.74 | 0.7328 |
| 46 |
Mapoly0005s0051
| [GO:0003723] RNA binding; [GO:0000339] RNA cap binding; [GO:0045292] mRNA cis splicing, via spliceosome; [GO:0051028] mRNA transport; [PF02854] MIF4G domain; [GO:0005515] protein binding; [KOG1104] Nuclear cap-binding complex, subunit NCBP1/CBP80; [K12882] nuclear cap-binding protein subunit 1; [GO:0016070] RNA metabolic process; [PTHR12412] CAP BINDING PROTEIN; [GO:0005846] nuclear cap binding complex; [PF09090] MIF4G like; [PF09088] MIF4G like | 60.76 | 0.7542 |
| 47 |
Mapoly0002s0324
| [GO:0005524] ATP binding; [GO:0016021] integral to membrane; [PTHR24223] FAMILY NOT NAMED; [PF00664] ABC transporter transmembrane region; [GO:0016887] ATPase activity; [GO:0006810] transport; [GO:0055085] transmembrane transport; [KOG0054] Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily; [GO:0042626] ATPase activity, coupled to transmembrane movement of substances; [PF00005] ABC transporter | 63.21 | 0.6780 |
| 48 |
Mapoly0001s0024
| [GO:0005634] nucleus; [GO:0003677] DNA binding; [KOG2402] Paf1/RNA polymerase II complex, RTF1 component (involved in regulation of TATA box-binding protein); [GO:0006352] DNA-dependent transcription, initiation; [GO:0016570] histone modification; [PTHR13115:SF8] SUBFAMILY NOT NAMED; [PF03126] Plus-3 domain; [PTHR13115] UNCHARACTERIZED | 63.29 | 0.7338 |
| 49 |
Mapoly0032s0034
| - | 63.47 | 0.7394 |
| 50 |
Mapoly0092s0032
| [PTHR22597] POLYCOMB GROUP PROTEIN; [PTHR22597:SF0] SUBFAMILY NOT NAMED; [PF09733] VEFS-Box of polycomb protein | 63.73 | 0.7451 |
