| 1 |
Mapoly0113s0020
| [GO:0003677] DNA binding; [PTHR12604:SF2] KU P70 DNA HELICASE; [K10884] ATP-dependent DNA helicase 2 subunit 1; [GO:0042162] telomeric DNA binding; [PF03730] Ku70/Ku80 C-terminal arm; [PF02735] Ku70/Ku80 beta-barrel domain; [PF03731] Ku70/Ku80 N-terminal alpha/beta domain; [GO:0043564] Ku70:Ku80 complex; [GO:0005634] nucleus; [GO:0004003] ATP-dependent DNA helicase activity; [GO:0003676] nucleic acid binding; [KOG2327] DNA-binding subunit of a DNA-dependent protein kinase (Ku70 autoantigen); [PTHR12604] KU AUTOANTIGEN DNA HELICASE; [GO:0003684] damaged DNA binding; [GO:0006303] double-strand break repair via nonhomologous end joining; [PF02037] SAP domain; [GO:0000723] telomere maintenance | 3.46 | 0.7531 |
| 2 |
Mapoly0158s0032
| [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [K10728] topoisomerase (DNA) II binding protein 1; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain | 4.36 | 0.7635 |
| 3 |
Mapoly0007s0101
| [PF09728] Myosin-like coiled-coil protein; [KOG1850] Myosin-like coiled-coil protein; [PTHR16127] TAXILIN; [GO:0019905] syntaxin binding | 8.00 | 0.7186 |
| 4 |
Mapoly0080s0034
| [2.1.1.43] Histone-lysine N-methyltransferase.; [KOG1082] Histone H3 (Lys9) methyltransferase SUV39H1/Clr4, required for transcriptional silencing; [K11419] histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43]; [PF05033] Pre-SET motif; [GO:0005515] protein binding; [PF00856] SET domain; [GO:0008270] zinc ion binding; [GO:0018024] histone-lysine N-methyltransferase activity; [PTHR22884] SET DOMAIN PROTEINS; [GO:0005634] nucleus; [GO:0034968] histone lysine methylation; [PF13771] PHD-like zinc-binding domain | 15.30 | 0.7433 |
| 5 |
Mapoly0052s0123
| [PTHR12616] VACUOLAR PROTEIN SORTING VPS41 | 18.30 | 0.7172 |
| 6 |
Mapoly0154s0015
| [PF00645] Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region; [GO:0003677] DNA binding; [PTHR15447] POLY [ADP-RIBOSE] POLYMERASE; [GO:0003950] NAD+ ADP-ribosyltransferase activity; [PF05406] WGR domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0006471] protein ADP-ribosylation; [PF08063] PADR1 (NUC008) domain; [K10798] poly [ADP-ribose] polymerase [EC:2.4.2.30]; [GO:0005634] nucleus; [PF02877] Poly(ADP-ribose) polymerase, regulatory domain; [2.4.2.30] NAD(+) ADP-ribosyltransferase.; [KOG1037] NAD+ ADP-ribosyltransferase Parp, required for poly-ADP ribosylation of nuclear proteins; [PF00644] Poly(ADP-ribose) polymerase catalytic domain | 25.30 | 0.6791 |
| 7 |
Mapoly0045s0049
| - | 26.38 | 0.6982 |
| 8 |
Mapoly0187s0003
| [PTHR22880] FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; [K06062] histone acetyltransferase [EC:2.3.1.48]; [GO:0005515] protein binding; [PF00439] Bromodomain; [GO:0008080] N-acetyltransferase activity; [PF00583] Acetyltransferase (GNAT) family; [2.3.1.48] Histone acetyltransferase. | 26.66 | 0.7080 |
| 9 |
Mapoly0015s0190
| - | 27.42 | 0.7099 |
| 10 |
Mapoly0004s0128
| [GO:0005524] ATP binding; [K08864] tousled-like kinase [EC:2.7.11.1]; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PTHR22974] MIXED LINEAGE PROTEIN KINASE; [KOG1151] Tousled-like protein kinase | 28.98 | 0.7129 |
| 11 |
Mapoly0065s0033
| [GO:0003723] RNA binding; [3.1.26.5] Ribonuclease P.; [K03538] ribonuclease P protein subunit POP4 [EC:3.1.26.5]; [GO:0000172] ribonuclease MRP complex; [PF01868] Domain of unknown function UPF0086; [PTHR13348] RIBONUCLEASE P; [GO:0006364] rRNA processing; [GO:0008033] tRNA processing; [GO:0030677] ribonuclease P complex; [GO:0006379] mRNA cleavage; [KOG4046] RNase MRP and P, subunit POP4/p29; [GO:0004540] ribonuclease activity | 29.07 | 0.6935 |
| 12 |
Mapoly0016s0023
| [GO:0008152] metabolic process; [PTHR11825] SUBGROUP IIII AMINOTRANSFERASE; [PF01063] Aminotransferase class IV; [GO:0003824] catalytic activity | 31.37 | 0.6122 |
| 13 |
Mapoly0007s0066
| [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PTHR19306:SF1] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5 SMC5; [KOG0979] Structural maintenance of chromosome protein SMC5/Spr18, SMC superfamily; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0000724] double-strand break repair via homologous recombination | 34.38 | 0.7129 |
| 14 |
Mapoly0029s0099
| [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PTHR23336:SF7] SUBFAMILY NOT NAMED; [KOG1845] MORC family ATPases; [PTHR23336] ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3. | 34.50 | 0.7010 |
| 15 |
Mapoly0063s0041
| [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR23340] ARGININE/SERINE RICH SPLICING FACTOR SF4/14; [PF01585] G-patch domain; [GO:0003676] nucleic acid binding; [PF01805] Surp module | 38.68 | 0.6988 |
| 16 |
Mapoly0001s0420
| [PTHR16212:SF4] SUBFAMILY NOT NAMED; [PF12530] Protein of unknown function (DUF3730); [PTHR16212] FAMILY NOT NAMED | 42.00 | 0.6790 |
| 17 |
Mapoly0005s0093
| [KOG1883] Cofactor required for Sp1 transcriptional activation, subunit 3; [PF11573] Mediator complex subunit 23; [PTHR12691] FAMILY NOT NAMED | 43.65 | 0.6869 |
| 18 |
Mapoly0113s0030
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [K14440] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:3.6.4.12]; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [3.6.4.12] DNA helicase.; [KOG1000] Chromatin remodeling protein HARP/SMARCAL1, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF43] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A-LIKE PROTEIN 1 | 46.86 | 0.6661 |
| 19 |
Mapoly0209s0009
| [PF04266] ASCH domain | 47.51 | 0.6658 |
| 20 |
Mapoly0045s0096
| [K08775] breast cancer 2 susceptibility protein; [PTHR11289] BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2; [GO:0003697] single-stranded DNA binding; [PF09169] BRCA2, helical; [PTHR11289:SF0] SUBFAMILY NOT NAMED; [GO:0006281] DNA repair; [PF09103] BRCA2, oligonucleotide/oligosaccharide-binding, domain 1; [GO:0000724] double-strand break repair via homologous recombination; [GO:0006310] DNA recombination | 49.78 | 0.6631 |
| 21 |
Mapoly0154s0010
| - | 49.84 | 0.6735 |
| 22 |
Mapoly0014s0032
| [PTHR14873] FAMILY NOT NAMED; [PF10521] Protein of unknown function (DUF2454); [PTHR14873:SF1] SUBFAMILY NOT NAMED | 50.48 | 0.6755 |
| 23 |
Mapoly0013s0109
| [PF00514] Armadillo/beta-catenin-like repeat; [PF00651] BTB/POZ domain; [GO:0005515] protein binding; [KOG0166] Karyopherin (importin) alpha; [PTHR23315] BETA CATENIN-RELATED ARMADILLO REPEAT-CONTAINING | 52.64 | 0.6825 |
| 24 |
Mapoly0023s0117
| [PTHR10139] DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11A; [PF04152] Mre11 DNA-binding presumed domain; [KOG2310] DNA repair exonuclease MRE11; [GO:0006259] DNA metabolic process; [PF00149] Calcineurin-like phosphoesterase; [GO:0006302] double-strand break repair; [GO:0016787] hydrolase activity; [GO:0030145] manganese ion binding; [GO:0005634] nucleus; [GO:0004527] exonuclease activity; [K10865] double-strand break repair protein MRE11; [GO:0004519] endonuclease activity | 56.43 | 0.6867 |
| 25 |
Mapoly0090s0070
| [PF00169] PH domain | 57.00 | 0.6542 |
| 26 |
Mapoly0059s0052
| [KOG0331] ATP-dependent RNA helicase; [GO:0005524] ATP binding; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding | 59.62 | 0.6342 |
| 27 |
Mapoly0020s0153
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF00580] UvrD/REP helicase N-terminal domain; [PF13361] UvrD-like helicase C-terminal domain; [GO:0016787] hydrolase activity; [KOG2108] 3'-5' DNA helicase; [3.6.4.12] DNA helicase.; [K03657] DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12]; [GO:0004003] ATP-dependent DNA helicase activity; [PTHR11070] UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER | 62.33 | 0.6667 |
| 28 |
Mapoly0014s0217
| [GO:0005515] protein binding; [KOG0322] G-protein beta subunit-like protein GNB1L, contains WD repeats; [PTHR19854:SF1] GB DEF: GUANINE NUCLEOTIDE-BINDING PROTEIN BETA SUBUNIT-LIKE PROTEIN 1 G PROTEIN BETA-S; [PTHR19854] TRANSDUCIN BETA-LIKE 3; [PF00400] WD domain, G-beta repeat | 62.74 | 0.6640 |
| 29 |
Mapoly0122s0062
| [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 | 63.28 | 0.6893 |
| 30 |
Mapoly0023s0072
| [3.1.27.-] Endoribonucleases producing other than 5'-phosphomonoesters.; [K13148] integrator complex subunit 11 [EC:3.1.27.-]; [PF07521] RNA-metabolising metallo-beta-lactamase; [PTHR11203] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF00753] Metallo-beta-lactamase superfamily; [PTHR11203:SF11] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF10996] Beta-Casp domain; [KOG1136] Predicted cleavage and polyadenylation specificity factor (CPSF subunit) | 65.67 | 0.6724 |
| 31 |
Mapoly0097s0033
| [PTHR10870] CELL CYCLE CHECKPOINT PROTEIN RAD1; [KOG3194] Checkpoint 9-1-1 complex, RAD1 component; [PF02144] Repair protein Rad1/Rec1/Rad17; [GO:0005634] nucleus; [K02830] cell cycle checkpoint protein [EC:3.1.11.2]; [GO:0006281] DNA repair; [3.1.11.2] Exodeoxyribonuclease III. | 66.33 | 0.6571 |
| 32 |
Mapoly0005s0045
| [PF15628] RRM in Demeter; [PTHR10359] A/G-SPECIFIC ADENINE GLYCOSYLASE/ENDONUCLEASE III | 67.48 | 0.6805 |
| 33 |
Mapoly0048s0100
| [PTHR18937:SF8] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC3; [GO:0005524] ATP binding; [KOG0964] Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3); [GO:0008280] cohesin core heterodimer; [GO:0005515] protein binding; [GO:0003682] chromatin binding; [GO:0007064] mitotic sister chromatid cohesion; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain; [K06669] structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) | 68.09 | 0.6804 |
| 34 |
Mapoly0033s0088
| [GO:0005515] protein binding; [PTHR19918:SF8] gb def: Meiosis-specific APC/C activator protein AMA1 (Activator of meiotic APC/C protei; [KOG0305] Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits; [K03363] cell division cycle 20, cofactor of APC complex; [PTHR19918] CELL DIVISION CYCLE 20 (CDC20) (FIZZY)-RELATED; [PF00400] WD domain, G-beta repeat | 70.57 | 0.6712 |
| 35 |
Mapoly0001s0391
| [GO:0005634] nucleus; [PF05965] F/Y rich C-terminus | 72.06 | 0.6781 |
| 36 |
Mapoly0066s0087
| [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF09382] RQC domain; [KOG0353] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [K10899] ATP-dependent DNA helicase Q1 [EC:3.6.4.12]; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain | 72.83 | 0.6565 |
| 37 |
Mapoly0038s0101
| [K12837] splicing factor U2AF 65 kDa subunit; [PTHR23139] RNA-BINDING PROTEIN; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG0120] Splicing factor U2AF, large subunit (RRM superfamily); [GO:0003676] nucleic acid binding; [PTHR23139:SF9] SPLICING FACTOR U2AF LARGE SUBUNIT; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 76.84 | 0.6778 |
| 38 |
Mapoly0001s0378
| [PTHR32086] FAMILY NOT NAMED; [K10891] fanconi anemia group D2 protein; [GO:0006281] DNA repair; [KOG4712] Uncharacterized conserved protein; [PF14631] Fanconi anaemia protein FancD2 nuclease | 78.07 | 0.6778 |
| 39 |
Mapoly0114s0002
| [PF03168] Late embryogenesis abundant protein; [PTHR31852] FAMILY NOT NAMED | 78.56 | 0.6683 |
| 40 |
Mapoly0015s0073
| [PF12780] P-loop containing dynein motor region D4; [PF12774] Hydrolytic ATP binding site of dynein motor region D1; [PF12775] P-loop containing dynein motor region D3; [GO:0005858] axonemal dynein complex; [GO:0030286] dynein complex; [PTHR10676] DYNEIN HEAVY CHAIN FAMILY PROTEIN; [PF03028] Dynein heavy chain and region D6 of dynein motor; [GO:0016887] ATPase activity; [KOG3595] Dyneins, heavy chain; [PF12777] Microtubule-binding stalk of dynein motor; [GO:0007018] microtubule-based movement; [PF08393] Dynein heavy chain, N-terminal region 2; [PF12781] ATP-binding dynein motor region D5; [GO:0003341] cilium movement; [PTHR10676:SF138] DYNEIN HEAVY CHAIN FAMILY PROTEIN; [GO:0003777] microtubule motor activity | 79.06 | 0.6594 |
| 41 |
Mapoly0029s0152
| [PTHR15239] UNCHARACTERIZED; [PF05833] Fibronectin-binding protein A N-terminus (FbpA); [PTHR15239:SF1] COLON CANCER ANTIGEN 1; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding; [PF11923] Domain of unknown function (DUF3441); [KOG2030] Predicted RNA-binding protein; [PF05670] Domain of unknown function (DUF814) | 80.14 | 0.6654 |
| 42 |
Mapoly0067s0005
| [PTHR24012] FAMILY NOT NAMED; [PTHR24012:SF39] SUBFAMILY NOT NAMED; [KOG0147] Transcriptional coactivator CAPER (RRM superfamily); [GO:0003676] nucleic acid binding; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [K13091] RNA-binding protein 39; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 80.78 | 0.6770 |
| 43 |
Mapoly0027s0186
| [GO:0005524] ATP binding; [K10866] DNA repair protein RAD50 [EC:3.6.-.-]; [PF13476] AAA domain; [GO:0008270] zinc ion binding; [PF04423] Rad50 zinc hook motif; [3.6.-.-] Acting on acid anhydrides.; [GO:0006281] DNA repair; [KOG0962] DNA repair protein RAD50, ABC-type ATPase/SMC superfamily; [PTHR18867:SF12] SUBFAMILY NOT NAMED; [PTHR18867] RAD50; [GO:0004518] nuclease activity; [GO:0030870] Mre11 complex; [PF13558] Putative exonuclease SbcCD, C subunit | 82.58 | 0.6708 |
| 44 |
Mapoly0016s0052
| [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat | 82.69 | 0.6094 |
| 45 |
Mapoly0033s0156
| [KOG0266] WD40 repeat-containing protein; [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [PF00400] WD domain, G-beta repeat | 84.62 | 0.6641 |
| 46 |
Mapoly0003s0120
| [GO:0003677] DNA binding; [PTHR12708:SF0] SUBFAMILY NOT NAMED; [GO:0006260] DNA replication; [PF12213] DNA polymerases epsilon N terminal; [2.7.7.7] DNA-directed DNA polymerase.; [PTHR12708] DNA POLYMERASE EPSILON SUBUNIT B; [KOG3818] DNA polymerase epsilon, subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [GO:0003887] DNA-directed DNA polymerase activity; [K02325] DNA polymerase epsilon subunit 2 [EC:2.7.7.7] | 85.30 | 0.6673 |
| 47 |
Mapoly0125s0024
| - | 87.16 | 0.6412 |
| 48 |
Mapoly0129s0012
| [GO:0003677] DNA binding; [K10885] ATP-dependent DNA helicase 2 subunit 2; [PTHR12604:SF3] KU P80 DNA HELICASE; [GO:0042162] telomeric DNA binding; [GO:0016817] hydrolase activity, acting on acid anhydrides; [PF03730] Ku70/Ku80 C-terminal arm; [PF02735] Ku70/Ku80 beta-barrel domain; [PF03731] Ku70/Ku80 N-terminal alpha/beta domain; [GO:0043564] Ku70:Ku80 complex; [GO:0005634] nucleus; [KOG2326] DNA-binding subunit of a DNA-dependent protein kinase (Ku80 autoantigen); [PF08785] Ku C terminal domain like; [GO:0004003] ATP-dependent DNA helicase activity; [PTHR12604] KU AUTOANTIGEN DNA HELICASE; [GO:0003684] damaged DNA binding; [GO:0006303] double-strand break repair via nonhomologous end joining; [GO:0006310] DNA recombination; [GO:0000723] telomere maintenance | 87.75 | 0.6240 |
| 49 |
Mapoly0111s0003
| - | 94.22 | 0.6601 |
| 50 |
Mapoly0039s0088
| [KOG0978] E3 ubiquitin ligase involved in syntaxin degradation | 95.25 | 0.6546 |
