Guide Gene
- Gene ID
- Mapoly0154s0015
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [PF00645] Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region; [GO:0003677] DNA binding; [PTHR15447] POLY [ADP-RIBOSE] POLYMERASE; [GO:0003950] NAD+ ADP-ribosyltransferase activity; [PF05406] WGR domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0006471] protein ADP-ribosylation; [PF08063] PADR1 (NUC008) domain; [K10798] poly [ADP-ribose] polymerase [EC:2.4.2.30]; [GO:0005634] nucleus; [PF02877] Poly(ADP-ribose) polymerase, regulatory domain; [2.4.2.30] NAD(+) ADP-ribosyltransferase.; [KOG1037] NAD+ ADP-ribosyltransferase Parp, required for poly-ADP ribosylation of nuclear proteins; [PF00644] Poly(ADP-ribose) polymerase catalytic domain
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0154s0015 [PF00645] Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region; [GO:0003677] DNA binding; [PTHR15447] POLY [ADP-RIBOSE] POLYMERASE; [GO:0003950] NAD+ ADP-ribosyltransferase activity; [PF05406] WGR domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0006471] protein ADP-ribosylation; [PF08063] PADR1 (NUC008) domain; [K10798] poly [ADP-ribose] polymerase [EC:2.4.2.30]; [GO:0005634] nucleus; [PF02877] Poly(ADP-ribose) polymerase, regulatory domain; [2.4.2.30] NAD(+) ADP-ribosyltransferase.; [KOG1037] NAD+ ADP-ribosyltransferase Parp, required for poly-ADP ribosylation of nuclear proteins; [PF00644] Poly(ADP-ribose) polymerase catalytic domain 0.00 1.0000 1 Mapoly0046s0105 [GO:0005097] Rab GTPase activator activity; [KOG2197] Ypt/Rab-specific GTPase-activating protein GYP7 and related proteins; [PTHR22957] TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN; [GO:0032313] regulation of Rab GTPase activity; [PF00566] Rab-GTPase-TBC domain 1.41 0.8052 2 Mapoly0113s0020 [GO:0003677] DNA binding; [PTHR12604:SF2] KU P70 DNA HELICASE; [K10884] ATP-dependent DNA helicase 2 subunit 1; [GO:0042162] telomeric DNA binding; [PF03730] Ku70/Ku80 C-terminal arm; [PF02735] Ku70/Ku80 beta-barrel domain; [PF03731] Ku70/Ku80 N-terminal alpha/beta domain; [GO:0043564] Ku70:Ku80 complex; [GO:0005634] nucleus; [GO:0004003] ATP-dependent DNA helicase activity; [GO:0003676] nucleic acid binding; [KOG2327] DNA-binding subunit of a DNA-dependent protein kinase (Ku70 autoantigen); [PTHR12604] KU AUTOANTIGEN DNA HELICASE; [GO:0003684] damaged DNA binding; [GO:0006303] double-strand break repair via nonhomologous end joining; [PF02037] SAP domain; [GO:0000723] telomere maintenance 2.45 0.7815 3 Mapoly0001s0551 [PF03470] XS zinc finger domain; [PTHR21596] RIBONUCLEASE P PROTEIN SUBUNIT P38-RELATED; [PF03469] XH domain; [PF03468] XS domain; [GO:0031047] gene silencing by RNA; [PTHR21596:SF3] TRANSCRIPTION FACTOR X1-LIKE 2.83 0.7932 4 Mapoly0057s0106 [K08288] protein kinase C substrate 80K-H; [PTHR12630:SF4] PROTEIN KINASE C SUBSTRATE 80K-H; [KOG2397] Protein kinase C substrate, 80 KD protein, heavy chain; [PTHR12630] N-LINKED OLIGOSACCHARIDE PROCESSING; [PF12999] Glucosidase II beta subunit-like; [PF13015] Glucosidase II beta subunit-like protein 5.83 0.6994 5 Mapoly0080s0073 [GO:0005524] ATP binding; [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [GO:0003676] nucleic acid binding; [KOG0922] DEAH-box RNA helicase; [GO:0046872] metal ion binding; [PF10354] Domain of unknown function (DUF2431) 7.07 0.7440 6 Mapoly0114s0002 [PF03168] Late embryogenesis abundant protein; [PTHR31852] FAMILY NOT NAMED 9.59 0.7728 7 Mapoly0095s0049 [PTHR13513] E3 UBIQUITIN-PROTEIN LIGASE UBR7; [GO:0008270] zinc ion binding; [PF02207] Putative zinc finger in N-recognin (UBR box); [KOG2752] Uncharacterized conserved protein, contains N-recognin-type Zn-finger; [GO:0004842] ubiquitin-protein ligase activity; [K11979] E3 ubiquitin-protein ligase UBR7 12.49 0.7316 8 Mapoly0007s0101 [PF09728] Myosin-like coiled-coil protein; [KOG1850] Myosin-like coiled-coil protein; [PTHR16127] TAXILIN; [GO:0019905] syntaxin binding 13.42 0.7150 9 Mapoly0038s0082 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [KOG0583] Serine/threonine protein kinase; [GO:0006468] protein phosphorylation; [PTHR24343:SF15] CARBON CATABOLITE-DEREPRESSING PROTEIN KINASE; [PF02149] Kinase associated domain 1; [PTHR24343] SERINE/THREONINE KINASE 15.75 0.7167 10 Mapoly0061s0032 [GO:0016020] membrane; [PF07933] Protein of unknown function (DUF1681); [PTHR12847:SF4] SUBFAMILY NOT NAMED; [KOG2500] Uncharacterized conserved protein; [GO:0006897] endocytosis; [PTHR12847] ATP-BINDING CASSETTE (ABC) TRANSPORTER-RELATED 18.14 0.7195 11 Mapoly0086s0067 [GO:0005524] ATP binding; [GO:0032300] mismatch repair complex; [KOG1979] DNA mismatch repair protein - MLH1 family; [PTHR10073] DNA MISMATCH REPAIR PROTEIN (MLH, PMS, MUTL); [PTHR10073:SF12] DNA MISMATCH REPAIR PROTEIN MUTL; [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [K08734] DNA mismatch repair protein MLH1; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01119] DNA mismatch repair protein, C-terminal domain 25.30 0.6791 12 Mapoly0033s0156 [KOG0266] WD40 repeat-containing protein; [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [PF00400] WD domain, G-beta repeat 25.46 0.7156 13 Mapoly0068s0006 - 27.57 0.6665 14 Mapoly0046s0064 [PF01702] Queuine tRNA-ribosyltransferase; [2.4.2.29] tRNA-guanine(34) transglycosylase.; [GO:0008479] queuine tRNA-ribosyltransferase activity; [PTHR11962] QUEUINE TRNA-RIBOSYLTRANSFERASE; [GO:0008616] queuosine biosynthetic process; [K00773] queuine tRNA-ribosyltransferase [EC:2.4.2.29]; [GO:0006400] tRNA modification; [KOG3909] Queuine-tRNA ribosyltransferase 28.72 0.7015 15 Mapoly0151s0042 [PTHR31500:SF0] SUBFAMILY NOT NAMED; [PF03479] Domain of unknown function (DUF296); [PTHR31500] FAMILY NOT NAMED 30.59 0.7086 16 Mapoly0004s0095 [KOG1303] Amino acid transporters; [PF01490] Transmembrane amino acid transporter protein; [PTHR22950] AMINO ACID TRANSPORTER 30.85 0.6844 17 Mapoly0074s0077 [PTHR22573] PHOSPHOHEXOMUTASE FAMILY MEMBER; [GO:0016868] intramolecular transferase activity, phosphotransferases; [PTHR22573:SF15] SUBFAMILY NOT NAMED; [GO:0005975] carbohydrate metabolic process; [K01836] phosphoacetylglucosamine mutase [EC:5.4.2.3]; [KOG2537] Phosphoglucomutase/phosphomannomutase; [PF02879] Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; [PF02878] Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; [5.4.2.3] Phosphoacetylglucosamine mutase.; [PF00408] Phosphoglucomutase/phosphomannomutase, C-terminal domain 35.87 0.6666 18 Mapoly0140s0033 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 37.68 0.6929 19 Mapoly0087s0021 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [KOG0969] DNA polymerase delta, catalytic subunit; [PTHR10322:SF11] DNA POLYMERASE DELTA CATALYTIC SUBUNIT; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [K02327] DNA polymerase delta subunit 1 [EC:2.7.7.7]; [PF14260] C4-type zinc-finger of DNA polymerase delta; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT 40.15 0.7059 20 Mapoly0005s0195 [KOG0031] Myosin regulatory light chain, EF-Hand protein superfamily; [PTHR20875] FAMILY NOT NAMED; [PTHR20875:SF0] SUBFAMILY NOT NAMED 40.91 0.6509 21 Mapoly0024s0064 [PF07962] Replication Fork Protection Component Swi3; [GO:0008270] zinc ion binding; [PTHR13220] TIMELESS INTERACTING-RELATED; [PF00098] Zinc knuckle; [GO:0006974] response to DNA damage stimulus; [GO:0005634] nucleus; [GO:0048478] replication fork protection; [GO:0003676] nucleic acid binding; [GO:0007049] cell cycle 42.43 0.6380 22 Mapoly0030s0061 [GO:0005663] DNA replication factor C complex; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [GO:0003689] DNA clamp loader activity; [PF00533] BRCA1 C Terminus (BRCT) domain; [K10754] replication factor C subunit 1; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08519] Replication factor RFC1 C terminal domain; [KOG1968] Replication factor C, subunit RFC1 (large subunit) 42.66 0.7051 23 Mapoly0016s0126 [GO:0000166] nucleotide binding; [PF00702] haloacid dehalogenase-like hydrolase; [PTHR24093] FAMILY NOT NAMED; [PF00690] Cation transporter/ATPase, N-terminus; [PF00689] Cation transporting ATPase, C-terminus; [GO:0046872] metal ion binding; [PF00122] E1-E2 ATPase; [KOG0202] Ca2+ transporting ATPase 43.95 0.5941 24 Mapoly0011s0044 [K03132] transcription initiation factor TFIID subunit 7; [PF04658] TAFII55 protein conserved region; [PTHR12228] TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED; [GO:0005669] transcription factor TFIID complex; [GO:0006367] transcription initiation from RNA polymerase II promoter 44.41 0.6825 25 Mapoly0021s0154 - 45.61 0.6889 26 Mapoly0015s0190 - 45.72 0.6954 27 Mapoly0009s0026 [GO:0005524] ATP binding; [GO:0016021] integral to membrane; [PTHR24223] FAMILY NOT NAMED; [PF00664] ABC transporter transmembrane region; [GO:0016887] ATPase activity; [GO:0006810] transport; [GO:0055085] transmembrane transport; [KOG0054] Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily; [GO:0042626] ATPase activity, coupled to transmembrane movement of substances; [PF00005] ABC transporter 46.13 0.6077 28 Mapoly0167s0006 - 47.81 0.6974 29 Mapoly0020s0153 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF00580] UvrD/REP helicase N-terminal domain; [PF13361] UvrD-like helicase C-terminal domain; [GO:0016787] hydrolase activity; [KOG2108] 3'-5' DNA helicase; [3.6.4.12] DNA helicase.; [K03657] DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12]; [GO:0004003] ATP-dependent DNA helicase activity; [PTHR11070] UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER 48.47 0.6854 30 Mapoly0105s0015 [GO:0003677] DNA binding; [KOG2393] Transcription initiation factor IIF, large subunit (RAP74); [GO:0032968] positive regulation of transcription elongation from RNA polymerase II promoter; [K03138] transcription initiation factor TFIIF subunit alpha; [PF05793] Transcription initiation factor IIF, alpha subunit (TFIIF-alpha); [PTHR13011] TFIIF-ALPHA; [GO:0005634] nucleus; [GO:0006367] transcription initiation from RNA polymerase II promoter 50.73 0.6908 31 Mapoly0056s0103 [2.4.1.15] Alpha,alpha-trehalose-phosphate synthase (UDP-forming).; [PF02358] Trehalose-phosphatase; [PTHR10788:SF6] TREHALOSE-6-PHOSPHATE SYNTHASE; [GO:0005992] trehalose biosynthetic process; [GO:0003824] catalytic activity; [KOG1050] Trehalose-6-phosphate synthase component TPS1 and related subunits; [K00697] alpha,alpha-trehalose-phosphate synthase (UDP-forming) [EC:2.4.1.15]; [PF00982] Glycosyltransferase family 20; [PTHR10788] TREHALOSE-6-PHOSPHATE SYNTHASE 51.50 0.6339 32 Mapoly0033s0088 [GO:0005515] protein binding; [PTHR19918:SF8] gb def: Meiosis-specific APC/C activator protein AMA1 (Activator of meiotic APC/C protei; [KOG0305] Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits; [K03363] cell division cycle 20, cofactor of APC complex; [PTHR19918] CELL DIVISION CYCLE 20 (CDC20) (FIZZY)-RELATED; [PF00400] WD domain, G-beta repeat 52.25 0.6925 33 Mapoly0083s0051 [PF12576] Protein of unknown function (DUF3754) 52.31 0.5990 34 Mapoly0004s0188 [GO:0005840] ribosome; [K02991] small subunit ribosomal protein S6e; [PTHR11502] 40S RIBOSOMAL PROTEIN S6; [KOG1646] 40S ribosomal protein S6; [GO:0003735] structural constituent of ribosome; [GO:0005622] intracellular; [PF01092] Ribosomal protein S6e; [GO:0006412] translation 52.55 0.7123 35 Mapoly0108s0026 [GO:0016020] membrane; [GO:0006486] protein glycosylation; [KOG2292] Oligosaccharyltransferase, STT3 subunit; [2.4.1.119] Transferred entry: 2.4.99.18.; [PTHR13872] 60S RIBOSOMAL PROTEIN L35; [K07151] dolichyl-diphosphooligosaccharide--protein glycosyltransferase [EC:2.4.1.119]; [PF02516] Oligosaccharyl transferase STT3 subunit; [GO:0004576] oligosaccharyl transferase activity 52.80 0.6733 36 Mapoly0029s0049 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0016602] CCAAT-binding factor complex; [KOG1657] CCAAT-binding factor, subunit C (HAP5); [GO:0043565] sequence-specific DNA binding; [PF00808] Histone-like transcription factor (CBF/NF-Y) and archaeal histone; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PTHR10252:SF8] TRANSCRIPTIONAL ACTIVATOR HAP5; [GO:0005622] intracellular; [PTHR10252] HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED 54.26 0.6996 37 Mapoly0072s0034 [K12178] COP9 signalosome complex subunit 4; [GO:0005515] protein binding; [KOG1497] COP9 signalosome, subunit CSN4; [PF01399] PCI domain; [PTHR10855] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4; [PTHR10855:SF2] COP9 SIGNALOSOME COMPLEX SUBUNIT 4 54.70 0.6620 38 Mapoly0154s0043 [GO:0055114] oxidation-reduction process; [GO:0005737] cytoplasm; [KOG2711] Glycerol-3-phosphate dehydrogenase/dihydroxyacetone 3-phosphate reductase; [GO:0006072] glycerol-3-phosphate metabolic process; [GO:0005975] carbohydrate metabolic process; [PF07479] NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; [GO:0016616] oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; [PF01210] NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; [GO:0046168] glycerol-3-phosphate catabolic process; [PTHR11728] GLYCEROL-3-PHOSPHATE DEHYDROGENASE; [GO:0051287] NAD binding; [GO:0004367] glycerol-3-phosphate dehydrogenase [NAD+] activity; [GO:0009331] glycerol-3-phosphate dehydrogenase complex 57.30 0.6400 39 Mapoly0043s0127 [GO:0031625] ubiquitin protein ligase binding; [GO:0031461] cullin-RING ubiquitin ligase complex; [GO:0006511] ubiquitin-dependent protein catabolic process; [K10609] cullin 4; [PF10557] Cullin protein neddylation domain; [PTHR11932] CULLIN; [PF00888] Cullin family; [KOG2167] Cullins; [PTHR11932:SF27] SUBFAMILY NOT NAMED 61.25 0.6795 40 Mapoly0084s0054 [K03029] 26S proteasome regulatory subunit N10; [PF02809] Ubiquitin interaction motif; [PF13519] von Willebrand factor type A domain; [GO:0006511] ubiquitin-dependent protein catabolic process; [PTHR10223] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4; [GO:0008540] proteasome regulatory particle, base subcomplex; [KOG2884] 26S proteasome regulatory complex, subunit RPN10/PSMD4 65.41 0.6905 41 Mapoly0029s0099 [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PTHR23336:SF7] SUBFAMILY NOT NAMED; [KOG1845] MORC family ATPases; [PTHR23336] ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3. 66.63 0.6805 42 Mapoly0004s0128 [GO:0005524] ATP binding; [K08864] tousled-like kinase [EC:2.7.11.1]; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PTHR22974] MIXED LINEAGE PROTEIN KINASE; [KOG1151] Tousled-like protein kinase 66.81 0.6892 43 Mapoly0009s0036 [KOG4259] Putative nucleic acid-binding protein Hcc-1/proliferation associated cytokine-inducible protein, contains SAP domain; [GO:0003676] nucleic acid binding; [PTHR21594] NUCLEAR PROTEIN HCC-1/THO1; [PF02037] SAP domain 69.20 0.6692 44 Mapoly0003s0064 [GO:0005759] mitochondrial matrix; [KOG2536] MAM33, mitochondrial matrix glycoprotein; [PF02330] Mitochondrial glycoprotein 69.60 0.5419 45 Mapoly0079s0037 [PTHR21467] HEAT-LIKE REPEAT-CONTAINING PROTEIN; [KOG0211] Protein phosphatase 2A regulatory subunit A and related proteins 69.91 0.6569 46 Mapoly0008s0275 [GO:0006486] protein glycosylation; [GO:0005783] endoplasmic reticulum; [GO:0004579] dolichyl-diphosphooligosaccharide-protein glycotransferase activity; [PTHR21049:SF0] SUBFAMILY NOT NAMED; [K12666] oligosaccharyltransferase complex subunit alpha (ribophorin I); [PF04597] Ribophorin I; [KOG2291] Oligosaccharyltransferase, alpha subunit (ribophorin I); [GO:0016021] integral to membrane; [PTHR21049] RIBOPHORIN I 71.64 0.6282 47 Mapoly0025s0110 - 71.77 0.6519 48 Mapoly0033s0073 [PTHR10984:SF2] THIOREDOXIN-RELATED; [GO:0045454] cell redox homeostasis; [PTHR10984] ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN; [PF13850] Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC); [KOG2667] COPII vesicle protein; [PF00085] Thioredoxin; [PF07970] Endoplasmic reticulum vesicle transporter 72.46 0.6694 49 Mapoly0131s0020 [KOG1010] Rb (Retinoblastoma tumor suppressor)-related protein; [PF01858] Retinoblastoma-associated protein A domain; [GO:0006357] regulation of transcription from RNA polymerase II promoter; [PF01857] Retinoblastoma-associated protein B domain; [GO:0005634] nucleus; [GO:0006351] transcription, DNA-dependent; [PF11934] Domain of unknown function (DUF3452); [GO:0051726] regulation of cell cycle; [PTHR13742] RETINOBLASTOMA-ASSOCIATED PROTEIN (RB)-RELATED; [GO:0007049] cell cycle 72.94 0.6668 50 Mapoly0050s0060 [PF04654] Protein of unknown function, DUF599; [PTHR31168] FAMILY NOT NAMED 76.42 0.6324 51 Mapoly1089s0002 [K09422] myb proto-oncogene protein, plant; [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding 79.37 0.5865 52 Mapoly0009s0203 - 79.46 0.6656 53 Mapoly0002s0217 [PF00183] Hsp90 protein; [GO:0005524] ATP binding; [GO:0006950] response to stress; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [GO:0006457] protein folding; [K04079] molecular chaperone HtpG; [PTHR11528] HEAT SHOCK PROTEIN 90; [KOG0019] Molecular chaperone (HSP90 family); [GO:0051082] unfolded protein binding 79.84 0.6286 54 Mapoly0092s0014 [PTHR32133] FAMILY NOT NAMED; [GO:0005515] protein binding; [PF00646] F-box domain 80.00 0.6534 55 Mapoly0001s0420 [PTHR16212:SF4] SUBFAMILY NOT NAMED; [PF12530] Protein of unknown function (DUF3730); [PTHR16212] FAMILY NOT NAMED 80.80 0.6553 56 Mapoly0007s0066 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PTHR19306:SF1] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5 SMC5; [KOG0979] Structural maintenance of chromosome protein SMC5/Spr18, SMC superfamily; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0000724] double-strand break repair via homologous recombination 81.55 0.6889 57 Mapoly0109s0020 [KOG4172] Predicted E3 ubiquitin ligase; [PF13920] Zinc finger, C3HC4 type (RING finger) 84.75 0.6503 58 Mapoly0075s0037 [K03257] translation initiation factor eIF-4A; [GO:0005524] ATP binding; [KOG0328] Predicted ATP-dependent RNA helicase FAL1, involved in rRNA maturation, DEAD-box superfamily; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding 84.91 0.6387 59 Mapoly0104s0042 [PTHR22846:SF2] TRANSDUCIN BETA-LIKE 1; [GO:0005515] protein binding; [PTHR22846] WD40 REPEAT PROTEIN; [KOG0273] Beta-transducin family (WD-40 repeat) protein; [PF08513] LisH; [PF00400] WD domain, G-beta repeat 90.22 0.6673 60 Mapoly0062s0046 [PTHR12203] KDEL (LYS-ASP-GLU-LEU) CONTAINING - RELATED; [KOG2458] Endoplasmic reticulum protein EP58, contains filamin rod domain and KDEL motif; [PF05686] Glycosyl transferase family 90 90.80 0.6208 61 Mapoly0113s0030 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [K14440] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:3.6.4.12]; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [3.6.4.12] DNA helicase.; [KOG1000] Chromatin remodeling protein HARP/SMARCAL1, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF43] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A-LIKE PROTEIN 1 91.65 0.6366 62 Mapoly0014s0224 [GO:0003677] DNA binding; [PTHR31251] FAMILY NOT NAMED; [GO:0005634] nucleus; [PF03110] SBP domain 94.02 0.6518 63 Mapoly0014s0097 [PF13414] TPR repeat; [KOG1308] Hsp70-interacting protein Hip/Transient component of progesterone receptor complexes and an Hsp70-binding protein; [PTHR22904:SF34] HSC70-INTERACTING PROTEIN; [PTHR22904] TPR REPEAT CONTAINING PROTEIN 94.74 0.6760 64 Mapoly0063s0041 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR23340] ARGININE/SERINE RICH SPLICING FACTOR SF4/14; [PF01585] G-patch domain; [GO:0003676] nucleic acid binding; [PF01805] Surp module 95.03 0.6624 65 Mapoly0001s0022 [GO:0016020] membrane; [GO:0055085] transmembrane transport; [PTHR30566] YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; [PF00924] Mechanosensitive ion channel 95.72 0.6551 66 Mapoly0031s0063 [PF12854] PPR repeat; [PF01535] PPR repeat; [PTHR24015] FAMILY NOT NAMED; [PF13041] PPR repeat family 101.02 0.5818 67 Mapoly0027s0188 [GO:0035299] inositol pentakisphosphate 2-kinase activity; [GO:0005524] ATP binding; [PTHR14456] INOSITOL POLYPHOSPHATE KINASE 1; [PF06090] Inositol-pentakisphosphate 2-kinase; [KOG4749] Inositol polyphosphate kinase 105.49 0.5755 68 Mapoly0184s0008 [KOG4282] Transcription factor GT-2 and related proteins, contains trihelix DNA-binding/SANT domain; [PTHR10032] ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS; [GO:0003700] sequence-specific DNA binding transcription factor activity; [GO:0005634] nucleus; [GO:0006351] transcription, DNA-dependent; [PF13837] Myb/SANT-like DNA-binding domain 106.49 0.5940 69 Mapoly0009s0087 [PTHR24011:SF38] SUBFAMILY NOT NAMED; [PTHR24011] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [KOG0117] Heterogeneous nuclear ribonucleoprotein R (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 106.96 0.6505 70 Mapoly0027s0186 [GO:0005524] ATP binding; [K10866] DNA repair protein RAD50 [EC:3.6.-.-]; [PF13476] AAA domain; [GO:0008270] zinc ion binding; [PF04423] Rad50 zinc hook motif; [3.6.-.-] Acting on acid anhydrides.; [GO:0006281] DNA repair; [KOG0962] DNA repair protein RAD50, ABC-type ATPase/SMC superfamily; [PTHR18867:SF12] SUBFAMILY NOT NAMED; [PTHR18867] RAD50; [GO:0004518] nuclease activity; [GO:0030870] Mre11 complex; [PF13558] Putative exonuclease SbcCD, C subunit 107.02 0.6581 71 Mapoly0123s0035 [PTHR14614] HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; [PF10294] Putative methyltransferase; [KOG3201] Uncharacterized conserved protein 107.33 0.5944 72 Mapoly0146s0004 [KOG1577] Aldo/keto reductase family proteins; [PTHR11732] ALDO/KETO REDUCTASE; [PF00248] Aldo/keto reductase family 108.90 0.6492 73 Mapoly0014s0134 [KOG2442] Uncharacterized conserved protein, contains PA domain; [PF02225] PA domain; [PTHR12174] SIGNAL PEPTIDE PEPTIDASE; [GO:0016021] integral to membrane; [PF04258] Signal peptide peptidase; [GO:0004190] aspartic-type endopeptidase activity 109.34 0.6429 74 Mapoly0076s0002 [PTHR14854] NIF3L1BP1 PROTEIN-RELATED; [KOG3215] Uncharacterized conserved protein; [GO:0000445] THO complex part of transcription export complex; [GO:0006397] mRNA processing; [K13176] THO complex subunit 7; [PF05615] Tho complex subunit 7 109.40 0.6279 75 Mapoly0002s0237 [PTHR12864] RAN BINDING PROTEIN 9-RELATED; [PF10607] CTLH/CRA C-terminal to LisH motif domain; [GO:0005515] protein binding; [KOG1477] SPRY domain-containing proteins; [PTHR12864:SF1] RAN BINDING PROTEIN 9-RELATED; [PF00622] SPRY domain 109.84 0.6147 76 Mapoly0169s0017 - 111.45 0.6252 77 Mapoly0068s0004 [GO:0004114] 3',5'-cyclic-nucleotide phosphodiesterase activity; [GO:0035556] intracellular signal transduction; [PF00233] 3'5'-cyclic nucleotide phosphodiesterase; [GO:0007165] signal transduction; [GO:0009190] cyclic nucleotide biosynthetic process; [GO:0016849] phosphorus-oxygen lyase activity; [PTHR11347] CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; [PF00211] Adenylate and Guanylate cyclase catalytic domain 111.54 0.6002 78 Mapoly0008s0010 [PF01464] Transglycosylase SLT domain 112.36 0.6194 79 Mapoly0033s0127 [PF01713] Smr domain; [PTHR13308] UNCHARACTERIZED; [PF08590] Domain of unknown function (DUF1771) 117.01 0.6645 80 Mapoly0004s0045 - 117.37 0.5936 81 Mapoly0020s0172 - 118.19 0.4956 82 Mapoly0091s0017 [GO:0005515] protein binding; [PTHR22937] RING FINGER CONTAINING PROTEIN; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [KOG2177] Predicted E3 ubiquitin ligase; [K11985] TRAF-interacting protein 120.12 0.6404 83 Mapoly0056s0068 [GO:0004356] glutamate-ammonia ligase activity; [GO:0006542] glutamine biosynthetic process; [GO:0006807] nitrogen compound metabolic process; [K01915] glutamine synthetase [EC:6.3.1.2]; [PTHR20852] GLUTAMINE SYNTHETASE; [PF03951] Glutamine synthetase, beta-Grasp domain; [6.3.1.2] Glutamate--ammonia ligase.; [KOG0683] Glutamine synthetase; [PF00120] Glutamine synthetase, catalytic domain 121.90 0.6145 84 Mapoly0003s0072 [K06693] 26S proteasome non-ATPase regulatory subunit 9; [PTHR12651] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9; [PTHR12651:SF1] 26S PROTEASOME REGULATORY SUBUNIT P27; [KOG3129] 26S proteasome regulatory complex, subunit PSMD9 122.08 0.6392 85 Mapoly0006s0222 [GO:0005524] ATP binding; [GO:0032300] mismatch repair complex; [KOG1977] DNA mismatch repair protein - MLH3 family; [PTHR10073:SF7] DNA MISMATCH REPAIR PROTEIN MLH3; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [GO:0007131] reciprocal meiotic recombination; [PTHR10073] DNA MISMATCH REPAIR PROTEIN (MLH, PMS, MUTL); [GO:0006298] mismatch repair; [PF08676] MutL C terminal dimerisation domain; [GO:0030983] mismatched DNA binding; [PF01119] DNA mismatch repair protein, C-terminal domain; [K08739] DNA mismatch repair protein MLH3 122.26 0.6368 86 Mapoly0033s0109 [PTHR22731] RIBONUCLEASE P/MRP SUBUNIT 123.84 0.5750 87 Mapoly0125s0024 - 125.84 0.6178 88 Mapoly0033s0129 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0003910] DNA ligase (ATP) activity; [PF04679] ATP dependent DNA ligase C terminal region; [PTHR10459] DNA LIGASE; [K10747] DNA ligase 1 [EC:6.5.1.1]; [PF01068] ATP dependent DNA ligase domain; [6.5.1.1] DNA ligase (ATP).; [GO:0006281] DNA repair; [PF04675] DNA ligase N terminus; [PTHR10459:SF10] DNA LIGASE I; [GO:0006310] DNA recombination; [KOG0967] ATP-dependent DNA ligase I 126.25 0.6344 89 Mapoly0014s0121 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0390] DNA repair protein, SNF2 family; [PF00271] Helicase conserved C-terminal domain 126.68 0.6396 90 Mapoly0036s0154 [KOG2606] OTU (ovarian tumor)-like cysteine protease; [PTHR12419] OTU DOMAIN CONTAINING PROTEIN; [PTHR12419:SF10] gb def: ENSANGP00000019868 (Fragment); [PF02338] OTU-like cysteine protease 128.34 0.6605 91 Mapoly0134s0033 [KOG0739] AAA+-type ATPase; [GO:0005524] ATP binding; [PTHR14690] UNCHARACTERIZED; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR14690:SF0] SUBFAMILY NOT NAMED 132.82 0.6135 92 Mapoly0005s0061 [PF00089] Trypsin; [PTHR22939] SERINE PROTEASE FAMILY S1C HTRA-RELATED; [GO:0005515] protein binding; [PF13180] PDZ domain; [KOG1320] Serine protease; [GO:0004252] serine-type endopeptidase activity; [GO:0006508] proteolysis 134.70 0.6504 93 Mapoly0029s0079 [GO:0042393] histone binding; [PF12165] Domain of unknown function (DUF3594); [GO:0006355] regulation of transcription, DNA-dependent; [KOG1632] Uncharacterized PHD Zn-finger protein; [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR12321] CPG BINDING PROTEIN 135.24 0.6415 94 Mapoly0105s0026 - 135.36 0.6376 95 Mapoly0001s0473 - 135.38 0.6502 96 Mapoly0020s0070 - 136.38 0.5170 97 Mapoly0014s0141 [PTHR10615:SF81] SUBFAMILY NOT NAMED; [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10615] HISTONE ACETYLTRANSFERASE 137.67 0.6318 98 Mapoly0103s0063 [PTHR21419] FAMILY NOT NAMED; [PF13517] Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 137.91 0.5779 99 Mapoly0027s0125 [GO:0005524] ATP binding; [GO:0035299] inositol pentakisphosphate 2-kinase activity; [PTHR14456] INOSITOL POLYPHOSPHATE KINASE 1; [PF06090] Inositol-pentakisphosphate 2-kinase; [KOG4749] Inositol polyphosphate kinase 138.48 0.6034 100 Mapoly0029s0152 [PTHR15239] UNCHARACTERIZED; [PF05833] Fibronectin-binding protein A N-terminus (FbpA); [PTHR15239:SF1] COLON CANCER ANTIGEN 1; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding; [PF11923] Domain of unknown function (DUF3441); [KOG2030] Predicted RNA-binding protein; [PF05670] Domain of unknown function (DUF814) 138.82 0.6310 101 Mapoly0080s0034 [2.1.1.43] Histone-lysine N-methyltransferase.; [KOG1082] Histone H3 (Lys9) methyltransferase SUV39H1/Clr4, required for transcriptional silencing; [K11419] histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43]; [PF05033] Pre-SET motif; [GO:0005515] protein binding; [PF00856] SET domain; [GO:0008270] zinc ion binding; [GO:0018024] histone-lysine N-methyltransferase activity; [PTHR22884] SET DOMAIN PROTEINS; [GO:0005634] nucleus; [GO:0034968] histone lysine methylation; [PF13771] PHD-like zinc-binding domain 139.03 0.6409 102 Mapoly0129s0012 [GO:0003677] DNA binding; [K10885] ATP-dependent DNA helicase 2 subunit 2; [PTHR12604:SF3] KU P80 DNA HELICASE; [GO:0042162] telomeric DNA binding; [GO:0016817] hydrolase activity, acting on acid anhydrides; [PF03730] Ku70/Ku80 C-terminal arm; [PF02735] Ku70/Ku80 beta-barrel domain; [PF03731] Ku70/Ku80 N-terminal alpha/beta domain; [GO:0043564] Ku70:Ku80 complex; [GO:0005634] nucleus; [KOG2326] DNA-binding subunit of a DNA-dependent protein kinase (Ku80 autoantigen); [PF08785] Ku C terminal domain like; [GO:0004003] ATP-dependent DNA helicase activity; [PTHR12604] KU AUTOANTIGEN DNA HELICASE; [GO:0003684] damaged DNA binding; [GO:0006303] double-strand break repair via nonhomologous end joining; [GO:0006310] DNA recombination; [GO:0000723] telomere maintenance 139.64 0.5968 103 Mapoly0082s0086 [PTHR11711] ADP RIBOSYLATION FACTOR-RELATED; [K07953] GTP-binding protein SAR1 [EC:3.6.5.-]; [3.6.5.-] Acting on GTP; involved in cellular and subcellular movement.; [PF00025] ADP-ribosylation factor family; [KOG0077] Vesicle coat complex COPII, GTPase subunit SAR1; [GO:0005622] intracellular; [GO:0006886] intracellular protein transport; [PTHR11711:SF12] GTP-BINDING PROTEIN SAR1; [GO:0005525] GTP binding 139.82 0.6163 104 Mapoly0001s0266 [GO:0003677] DNA binding; [PF01192] RNA polymerase Rpb6; [KOG3405] RNA polymerase subunit K; [PTHR10773] DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2; [GO:0006351] transcription, DNA-dependent; [GO:0003899] DNA-directed RNA polymerase activity; [K03014] DNA-directed RNA polymerases I, II, and III subunit RPABC2 140.98 0.6509 105 Mapoly0056s0014 [GO:0016021] integral to membrane; [KOG3574] Acetyl-CoA transporter; [GO:0008521] acetyl-CoA transporter activity; [PTHR12778:SF3] SOLUTE CARRIER FAMILY 33 (ACETYL-COA TRANSPORTER); [PF13000] Acetyl-coenzyme A transporter 1; [PTHR12778] SOLUTE CARRIER FAMILY 33 (ACETYL-COA TRANSPORTER)-RELATED 141.62 0.5817 106 Mapoly0114s0016 [GO:0005783] endoplasmic reticulum; [KOG0675] Calnexin; [PTHR11073] CALRETICULIN AND CALNEXIN; [K08054] calnexin; [PF00262] Calreticulin family; [GO:0006457] protein folding; [GO:0051082] unfolded protein binding; [GO:0005509] calcium ion binding; [PTHR11073:SF1] CALNEXIN 141.84 0.5431 107 Mapoly0138s0044 - 142.13 0.5741 108 Mapoly0054s0064 [PF03178] CPSF A subunit region; [PF10433] Mono-functional DNA-alkylating methyl methanesulfonate N-term; [PTHR10644:SF3] DNA DAMAGE-BINDING PROTEIN 1 (DAMAGE-SPECIFIC DNA-BINDING PROTEIN 1)(UV-DAMAGED DNA-BINDING FACTOR); [K10610] DNA damage-binding protein 1; [GO:0005634] nucleus; [PTHR10644] DNA REPAIR/RNA PROCESSING CPSF FAMILY; [KOG1897] Damage-specific DNA binding complex, subunit DDB1; [GO:0003676] nucleic acid binding 142.48 0.5987 109 Mapoly0052s0111 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG4206] Spliceosomal protein snRNP-U1A/U2B; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED 143.74 0.6386 110 Mapoly0125s0028 [GO:0000166] nucleotide binding; [PF00702] haloacid dehalogenase-like hydrolase; [KOG0205] Plasma membrane H+-transporting ATPase; [PTHR24093] FAMILY NOT NAMED; [PF00690] Cation transporter/ATPase, N-terminus; [GO:0046872] metal ion binding; [PF00122] E1-E2 ATPase 144.64 0.6404 111 Mapoly0008s0026 [GO:0019773] proteasome core complex, alpha-subunit complex; [PTHR11599:SF14] PROTEASOME SUBUNIT ALPHA TYPE 5; [GO:0051603] proteolysis involved in cellular protein catabolic process; [KOG0176] 20S proteasome, regulatory subunit alpha type PSMA5/PUP2; [GO:0006511] ubiquitin-dependent protein catabolic process; [GO:0004175] endopeptidase activity; [GO:0004298] threonine-type endopeptidase activity; [PF10584] Proteasome subunit A N-terminal signature; [GO:0005839] proteasome core complex; [PF00227] Proteasome subunit; [PTHR11599] PROTEASOME SUBUNIT ALPHA/BETA 145.33 0.6209 112 Mapoly0060s0008 [PF07748] Glycosyl hydrolases family 38 C-terminal domain; [GO:0015923] mannosidase activity; [PTHR11607] ALPHA-MANNOSIDASE; [GO:0004559] alpha-mannosidase activity; [GO:0006013] mannose metabolic process; [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [PF09261] Alpha mannosidase, middle domain; [GO:0005975] carbohydrate metabolic process; [GO:0008270] zinc ion binding; [K01231] alpha-mannosidase II [EC:3.2.1.114]; [PF01074] Glycosyl hydrolases family 38 N-terminal domain; [PTHR11607:SF4] MANNOSIDASE ALPHA CLASS 2A; [3.2.1.114] Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase.; [KOG1958] Glycosyl hydrolase, family 38 - alpha-mannosidase 146.55 0.6143 113 Mapoly0019s0098 [PF13345] Domain of unknown function (DUF4098) 147.97 0.6071 114 Mapoly0007s0143 [KOG2235] Uncharacterized conserved protein; [PTHR31057] FAMILY NOT NAMED; [PF09743] Uncharacterized conserved protein (DUF2042); [PTHR31057:SF0] SUBFAMILY NOT NAMED 148.58 0.6201 115 Mapoly0005s0128 [KOG2297] Predicted translation factor, contains W2 domain; [GO:0005515] protein binding; [PF02020] eIF4-gamma/eIF5/eIF2-epsilon; [PTHR14208] BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN; [PTHR14208:SF2] BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN 148.73 0.6331 116 Mapoly0045s0049 - 149.73 0.6215 117 Mapoly0103s0058 [KOG1978] DNA mismatch repair protein - MLH2/PMS1/Pms2 family; [GO:0005524] ATP binding; [GO:0032300] mismatch repair complex; [PTHR10073] DNA MISMATCH REPAIR PROTEIN (MLH, PMS, MUTL); [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [GO:0006298] mismatch repair; [K10858] DNA mismatch repair protein PMS2; [PTHR10073:SF9] DNA MISMATCH REPAIR PROTEIN PMS1; [PF08676] MutL C terminal dimerisation domain; [GO:0030983] mismatched DNA binding; [PF01119] DNA mismatch repair protein, C-terminal domain 150.20 0.5166 118 Mapoly0006s0255 [GO:0003723] RNA binding; [PTHR10288] KH DOMAIN CONTAINING RNA BINDING PROTEIN; [PF00013] KH domain; [KOG2192] PolyC-binding hnRNP-K protein HRB57A/hnRNP, contains KH domain; [K13210] far upstream element-binding protein 150.40 0.6456 119 Mapoly0052s0101 - 153.28 0.6086 120 Mapoly0025s0057 [PTHR10907] REGUCALCIN; [PF08450] SMP-30/Gluconolaconase/LRE-like region; [KOG4499] Ca2+-binding protein Regucalcin/SMP30 154.30 0.6231 121 Mapoly0024s0008 [GO:0003677] DNA binding; [KOG1793] Uncharacterized conserved protein; [PF08711] TFIIS helical bundle-like domain; [GO:0005634] nucleus; [GO:0006351] transcription, DNA-dependent; [PTHR22908] MIDASIN-RELATED 156.98 0.5795 122 Mapoly0159s0016 - 158.09 0.5543 123 Mapoly0091s0053 [KOG0963] Transcription factor/CCAAT displacement protein CDP1; [PTHR14043] CCAAT DISPLACEMENT PROTEIN-RELATED; [K09313] homeobox protein cut-like; [GO:0006891] intra-Golgi vesicle-mediated transport; [GO:0030173] integral to Golgi membrane; [PF08172] CASP C terminal 158.27 0.5920 124 Mapoly0052s0071 [GO:0003951] NAD+ kinase activity; [KOG2178] Predicted sugar kinase; [2.7.1.23] NAD(+) kinase.; [GO:0006741] NADP biosynthetic process; [PTHR20275:SF0] SUBFAMILY NOT NAMED; [K00858] NAD+ kinase [EC:2.7.1.23]; [GO:0008152] metabolic process; [PTHR20275] FAMILY NOT NAMED; [PF01513] ATP-NAD kinase 158.54 0.6012 125 Mapoly0127s0050 [GO:0005515] protein binding; [PF13414] TPR repeat; [PF00515] Tetratricopeptide repeat; [PTHR22904] TPR REPEAT CONTAINING PROTEIN; [PF13877] Potential Monad-binding region of RPAP3 159.30 0.6183 126 Mapoly0045s0045 [KOG2118] Predicted membrane protein, contains two CBS domains; [PTHR12064] ANCIENT CONSERVED DOMAIN PROTEIN-RELATED; [PF01595] Domain of unknown function DUF21 159.49 0.5952 127 Mapoly0001s0066 [PF04884] Vitamin B6 photo-protection and homoeostasis; [KOG4249] Uncharacterized conserved protein; [PTHR12770] FAMILY NOT NAMED 162.06 0.6076 128 Mapoly0086s0056 [1.1.1.200] Aldose-6-phosphate reductase (NADPH).; [KOG1577] Aldo/keto reductase family proteins; [PTHR11732] ALDO/KETO REDUCTASE; [PF00248] Aldo/keto reductase family; [K00085] aldose-6-phosphate reductase (NADPH2) [EC:1.1.1.200] 162.92 0.6287 129 Mapoly0176s0004 [PTHR31245] FAMILY NOT NAMED 162.98 0.5175 130 Mapoly0006s0093 [GO:0009058] biosynthetic process; [K00654] serine palmitoyltransferase [EC:2.3.1.50]; [GO:0030170] pyridoxal phosphate binding; [PTHR13693] CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE; [KOG1357] Serine palmitoyltransferase; [2.3.1.50] Serine C-palmitoyltransferase.; [PTHR13693:SF3] SERINE PALMITOYLTRANSFERASE 2; [PF00155] Aminotransferase class I and II 163.33 0.5954 131 Mapoly0086s0078 [GO:0003677] DNA binding; [GO:0006275] regulation of DNA replication; [GO:0030337] DNA polymerase processivity factor activity; [PTHR11352] PROLIFERATING CELL NUCLEAR ANTIGEN; [PF00705] Proliferating cell nuclear antigen, N-terminal domain; [KOG1636] DNA polymerase delta processivity factor (proliferating cell nuclear antigen); [PF02747] Proliferating cell nuclear antigen, C-terminal domain 164.95 0.6356 132 Mapoly0020s0073 [PF05602] Cleft lip and palate transmembrane protein 1 (CLPTM1); [PTHR21347] CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED; [KOG2489] Transmembrane protein; [PTHR21347:SF0] SUBFAMILY NOT NAMED 166.77 0.6117 133 Mapoly0014s0204 [PTHR24012] FAMILY NOT NAMED; [PTHR24012:SF31] SUBFAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 167.71 0.6207 134 Mapoly0091s0013 [GO:0003723] RNA binding; [KOG2202] U2 snRNP splicing factor, small subunit, and related proteins; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PTHR12620] U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT; [GO:0005634] nucleus; [K12836] splicing factor U2AF 35 kDa subunit; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [GO:0046872] metal ion binding 169.31 0.6413 135 Mapoly0004s0143 [PTHR32133] FAMILY NOT NAMED; [GO:0005515] protein binding; [PF00646] F-box domain 170.29 0.5636 136 Mapoly0080s0093 [GO:0003677] DNA binding; [PF00046] Homeobox domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR12628] POLYCOMB-LIKE TRANSCRIPTION FACTOR 170.65 0.6248 137 Mapoly0001s0415 [PF05641] Agenet domain 171.24 0.5860 138 Mapoly0055s0054 [PTHR13476] UNCHARACTERIZED; [PTHR13476:SF0] SUBFAMILY NOT NAMED; [PF09340] Histone acetyltransferase subunit NuA4; [K11344] chromatin modification-related protein EAF6 173.13 0.6185 139 Mapoly0158s0019 [PTHR24012] FAMILY NOT NAMED; [KOG4205] RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 174.20 0.6182 140 Mapoly0100s0038 [GO:0007264] small GTPase mediated signal transduction; [PTHR24073] FAMILY NOT NAMED; [KOG0098] GTPase Rab2, small G protein superfamily; [PF15305] Intraflagellar transport protein 43; [PF00071] Ras family; [GO:0005525] GTP binding; [GO:0030991] intraflagellar transport particle A 174.71 0.6086 141 Mapoly0016s0188 [K10536] agmatine deiminase [EC:3.5.3.12]; [PTHR31377:SF0] SUBFAMILY NOT NAMED; [GO:0004668] protein-arginine deiminase activity; [3.5.3.12] Agmatine deiminase.; [PF04371] Porphyromonas-type peptidyl-arginine deiminase; [GO:0009446] putrescine biosynthetic process; [PTHR31377] FAMILY NOT NAMED 175.82 0.6055 142 Mapoly0011s0129 [KOG0131] Splicing factor 3b, subunit 4; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [PTHR24011] FAMILY NOT NAMED; [PF07145] Ataxin-2 C-terminal region; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 176.69 0.6133 143 Mapoly0005s0201 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005515] protein binding; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PTHR12348] TSC22; [PF00498] FHA domain 177.51 0.6147 144 Mapoly0111s0035 [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PTHR12547] CCCH ZINC FINGER/TIS11-RELATED; [GO:0046872] metal ion binding; [KOG1677] CCCH-type Zn-finger protein 180.44 0.6166 145 Mapoly0054s0094 [PTHR11216] EH DOMAIN; [PF00350] Dynamin family; [GO:0003924] GTPase activity; [KOG1954] Endocytosis/signaling protein EHD1; [PTHR11216:SF31] EH DOMAIN CONTAINING/PAST 1, 2, 3; [GO:0005525] GTP binding; [PF12763] Cytoskeletal-regulatory complex EF hand 181.25 0.5743 146 Mapoly0138s0027 [PTHR14845] FAMILY NOT NAMED; [GO:0036064] cilium basal body; [PTHR14845:SF0] SUBFAMILY NOT NAMED 181.42 0.5828 147 Mapoly0187s0003 [PTHR22880] FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; [K06062] histone acetyltransferase [EC:2.3.1.48]; [GO:0005515] protein binding; [PF00439] Bromodomain; [GO:0008080] N-acetyltransferase activity; [PF00583] Acetyltransferase (GNAT) family; [2.3.1.48] Histone acetyltransferase. 184.02 0.6190 148 Mapoly0058s0108 [GO:0003677] DNA binding; [KOG0214] RNA polymerase II, second largest subunit; [PF04567] RNA polymerase Rpb2, domain 5; [PF04565] RNA polymerase Rpb2, domain 3; [PTHR20856] DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2; [PF00562] RNA polymerase Rpb2, domain 6; [PF04566] RNA polymerase Rpb2, domain 4; [GO:0032549] ribonucleoside binding; [PF04561] RNA polymerase Rpb2, domain 2; [GO:0006351] transcription, DNA-dependent; [GO:0003899] DNA-directed RNA polymerase activity; [PF04560] RNA polymerase Rpb2, domain 7; [PF04563] RNA polymerase beta subunit 185.20 0.6196 149 Mapoly0071s0036 [GO:0005515] protein binding; [PTHR13833] FAMILY NOT NAMED; [PF01436] NHL repeat 185.47 0.5983 150 Mapoly0013s0011 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 186.04 0.6298 151 Mapoly0001s0061 [K09422] myb proto-oncogene protein, plant; [KOG0048] Transcription factor, Myb superfamily; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [PF13921] Myb-like DNA-binding domain 186.17 0.5302 152 Mapoly0043s0114 - 186.31 0.5036 153 Mapoly0154s0010 - 187.16 0.6042 154 Mapoly0052s0081 [GO:0016020] membrane; [PTHR11654] OLIGOPEPTIDE TRANSPORTER-RELATED; [PF00854] POT family; [GO:0006810] transport; [GO:0005215] transporter activity 189.40 0.5958 155 Mapoly0035s0029 [PF10602] 26S proteasome subunit RPN7; [KOG0686] COP9 signalosome, subunit CSN1; [GO:0005515] protein binding; [PTHR14145] 26S PROTESOME SUBUNIT 6; [PTHR14145:SF2] COP9 SIGNALOSOME COMPLEX SUBUNIT 1; [PF01399] PCI domain; [K12175] COP9 signalosome complex subunit 1 192.19 0.6173 156 Mapoly0038s0101 [K12837] splicing factor U2AF 65 kDa subunit; [PTHR23139] RNA-BINDING PROTEIN; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG0120] Splicing factor U2AF, large subunit (RRM superfamily); [GO:0003676] nucleic acid binding; [PTHR23139:SF9] SPLICING FACTOR U2AF LARGE SUBUNIT; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 193.80 0.6263 157 Mapoly0069s0082 [PTHR23002] ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding 194.93 0.6247 158 Mapoly0001s0064 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [GO:0008173] RNA methyltransferase activity; [PTHR12029] RNA METHYLTRANSFERASE; [KOG0838] RNA Methylase, SpoU family; [PF00588] SpoU rRNA Methylase family 200.62 0.6286 159 Mapoly0038s0009 [K11279] nucleosome assembly protein 1-like 1; [PF00956] Nucleosome assembly protein (NAP); [PTHR11875:SF7] NUCLEOSOME ASSEMBLY PROTEIN; [GO:0005634] nucleus; [GO:0006334] nucleosome assembly; [PTHR11875] TESTIS-SPECIFIC Y-ENCODED PROTEIN; [KOG1507] Nucleosome assembly protein NAP-1 205.30 0.5741 160 Mapoly0191s0009 [PTHR23123] PHD/F-BOX CONTAINING PROTEIN; [1.14.11.27] [Histone H3]-lysine-36 demethylase.; [PF13621] Cupin-like domain; [K10276] F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27] 205.85 0.6125 161 Mapoly0045s0096 [K08775] breast cancer 2 susceptibility protein; [PTHR11289] BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2; [GO:0003697] single-stranded DNA binding; [PF09169] BRCA2, helical; [PTHR11289:SF0] SUBFAMILY NOT NAMED; [GO:0006281] DNA repair; [PF09103] BRCA2, oligonucleotide/oligosaccharide-binding, domain 1; [GO:0000724] double-strand break repair via homologous recombination; [GO:0006310] DNA recombination 207.28 0.5805 162 Mapoly0023s0117 [PTHR10139] DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11A; [PF04152] Mre11 DNA-binding presumed domain; [KOG2310] DNA repair exonuclease MRE11; [GO:0006259] DNA metabolic process; [PF00149] Calcineurin-like phosphoesterase; [GO:0006302] double-strand break repair; [GO:0016787] hydrolase activity; [GO:0030145] manganese ion binding; [GO:0005634] nucleus; [GO:0004527] exonuclease activity; [K10865] double-strand break repair protein MRE11; [GO:0004519] endonuclease activity 207.49 0.6222 163 Mapoly0070s0095 [PTHR23215] ZINC FINGER PROTEIN 207; [KOG2893] Zn finger protein 208.12 0.6140 164 Mapoly0111s0025 [GO:0005783] endoplasmic reticulum; [KOG0674] Calreticulin; [PTHR11073] CALRETICULIN AND CALNEXIN; [PF00262] Calreticulin family; [GO:0006457] protein folding; [K08057] calreticulin; [GO:0051082] unfolded protein binding; [GO:0005509] calcium ion binding 208.92 0.6110 165 Mapoly0009s0244 [PTHR13420:SF0] SUBFAMILY NOT NAMED; [PTHR13420] UNCHARACTERIZED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 208.95 0.5524 166 Mapoly0027s0185 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF39] CDC2-RELATED PROTEIN KINASE; [KOG0600] Cdc2-related protein kinase; [K08819] Cdc2-related kinase, arginine/serine-rich [EC:2.7.11.22]; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 211.00 0.6181 167 Mapoly0014s0064 [PTHR10552] U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A; [K11092] U2 small nuclear ribonucleoprotein A'; [KOG1644] U2-associated snRNP A' protein; [PF14580] Leucine-rich repeat 211.14 0.6169 168 Mapoly0066s0078 [GO:0034453] microtubule anchoring; [PTHR15431:SF3] FGFR1 ONCOGENE PARTNER; [PTHR15431] FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN; [GO:0005815] microtubule organizing center; [PF09398] FOP N terminal dimerisation domain 211.53 0.5953 169 Mapoly0084s0045 [PF07719] Tetratricopeptide repeat; [KOG1211] Amidases; [PF13414] TPR repeat; [PTHR11895] AMIDASE; [GO:0016884] carbon-nitrogen ligase activity, with glutamine as amido-N-donor; [PTHR11895:SF6] AMIDASE; [PF01425] Amidase 215.75 0.5891 170 Mapoly1635s0001 [PF03083] Sugar efflux transporter for intercellular exchange; [KOG1623] Multitransmembrane protein; [PTHR10791] RAG1-ACTIVATING PROTEIN 1 216.21 0.6127 171 Mapoly0158s0032 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [K10728] topoisomerase (DNA) II binding protein 1; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 221.39 0.6119 172 Mapoly0095s0046 [PF13919] Asx homology domain; [GO:0006355] regulation of transcription, DNA-dependent; [PTHR10071] TRANSCRIPTION FACTOR GATA (GATA BINDING FACTOR); [GO:0043565] sequence-specific DNA binding; [GO:0008270] zinc ion binding; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF00320] GATA zinc finger 223.30 0.5846 173 Mapoly0005s0202 [KOG1454] Predicted hydrolase/acyltransferase (alpha/beta hydrolase superfamily); [PTHR10992] ALPHA/BETA HYDROLASE FOLD-CONTAINING PROTEIN; [PF12697] Alpha/beta hydrolase family 225.43 0.5742 174 Mapoly0014s0208 [KOG1587] Cytoplasmic dynein intermediate chain; [GO:0005515] protein binding; [PTHR12442:SF5] TESTIS DEVELOPMENT PROTEIN NYD-SP29; [PTHR12442] DYNEIN INTERMEDIATE CHAIN; [PF00400] WD domain, G-beta repeat 225.45 0.6063 175 Mapoly0103s0067 [GO:0030599] pectinesterase activity; [PF01095] Pectinesterase; [GO:0042545] cell wall modification; [K01051] pectinesterase [EC:3.1.1.11]; [PTHR31321] FAMILY NOT NAMED; [3.1.1.11] Pectinesterase.; [GO:0005618] cell wall 225.73 0.5608 176 Mapoly0007s0152 [PTHR23147] SERINE/ARGININE RICH SPLICING FACTOR; [KOG4207] Predicted splicing factor, SR protein superfamily; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 226.50 0.6072 177 Mapoly0049s0118 [PTHR32002] FAMILY NOT NAMED; [PF02042] RWP-RK domain 226.73 0.5978 178 Mapoly0028s0018 - 227.43 0.4661 179 Mapoly0067s0005 [PTHR24012] FAMILY NOT NAMED; [PTHR24012:SF39] SUBFAMILY NOT NAMED; [KOG0147] Transcriptional coactivator CAPER (RRM superfamily); [GO:0003676] nucleic acid binding; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [K13091] RNA-binding protein 39; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 227.96 0.6164 180 Mapoly0178s0022 [PF00072] Response regulator receiver domain; [GO:0035556] intracellular signal transduction; [PTHR16305] TESTICULAR SOLUBLE ADENYLYL CYCLASE; [GO:0000160] phosphorelay signal transduction system; [GO:0009190] cyclic nucleotide biosynthetic process; [GO:0016849] phosphorus-oxygen lyase activity; [PF00211] Adenylate and Guanylate cyclase catalytic domain 228.00 0.5908 181 Mapoly0131s0036 [PF01453] D-mannose binding lectin 230.14 0.5356 182 Mapoly0066s0100 [PTHR31515] FAMILY NOT NAMED; [PTHR31515:SF0] SUBFAMILY NOT NAMED 230.67 0.4875 183 Mapoly0162s0020 - 231.47 0.5566 184 Mapoly0033s0081 [PF07719] Tetratricopeptide repeat; [PTHR12197:SF13] SET AND MYND DOMAIN CONTAINING; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF00856] SET domain; [PTHR12197] SET AND MYND DOMAIN CONTAINING; [KOG4234] TPR repeat-containing protein 231.64 0.5654 185 Mapoly0032s0098 [GO:0055114] oxidation-reduction process; [GO:0016706] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; [GO:0016491] oxidoreductase activity; [PTHR10869] PROLYL 4-HYDROXYLASE ALPHA SUBUNIT; [1.14.11.2] Procollagen-proline dioxygenase.; [K00472] prolyl 4-hydroxylase [EC:1.14.11.2]; [PF03171] 2OG-Fe(II) oxygenase superfamily 231.88 0.5821 186 Mapoly0008s0182 [3.1.2.15] Ubiquitin thiolesterase.; [K11851] ubiquitin carboxyl-terminal hydrolase 30 [EC:3.1.2.15]; [PF00443] Ubiquitin carboxyl-terminal hydrolase; [GO:0006511] ubiquitin-dependent protein catabolic process; [PTHR24006] FAMILY NOT NAMED 231.93 0.5463 187 Mapoly0036s0012 [GO:0003723] RNA binding; [KOG3013] Exosomal 3'-5' exoribonuclease complex, subunit Rrp4; [PTHR21321] PNAS-3 RELATED; [PTHR21321:SF1] PNAS-3 RELATED; [K03679] exosome complex component RRP4; [GO:0000178] exosome (RNase complex) 233.27 0.5398 188 Mapoly0144s0028 [GO:0016020] membrane; [PTHR11384] ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER; [GO:0005524] ATP binding; [KOG0060] Long-chain acyl-CoA transporter, ABC superfamily (involved in peroxisome organization and biogenesis); [PF06472] ABC transporter transmembrane region 2; [GO:0016887] ATPase activity; [GO:0006810] transport; [PF00005] ABC transporter 233.49 0.5884 189 Mapoly0022s0184 [GO:0016020] membrane; [PTHR11654] OLIGOPEPTIDE TRANSPORTER-RELATED; [PF00854] POT family; [KOG1237] H+/oligopeptide symporter; [GO:0006810] transport; [GO:0005215] transporter activity 234.61 0.5423 190 Mapoly0013s0062 [GO:0003677] DNA binding; [PTHR15348:SF0] SUBFAMILY NOT NAMED; [PF01388] ARID/BRIGHT DNA binding domain; [GO:0005622] intracellular; [PTHR15348] AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN (ARID DOMAIN- CONTAINING PROTEIN) (DEAD RINGER PROTEIN) (B-CELL REGULATOR OF IGH TRANSCRIPTION) (BRIGHT) 236.71 0.6104 191 Mapoly0125s0010 [PTHR23213] FORMIN-RELATED 239.84 0.5806 192 Mapoly0104s0036 [GO:0016020] membrane; [PF00072] Response regulator receiver domain; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PF03924] CHASE domain; [GO:0000160] phosphorelay signal transduction system; [KOG0519] Sensory transduction histidine kinase; [GO:0007165] signal transduction; [PTHR24423] TWO-COMPONENT SENSOR HISTIDINE KINASE; [PF00512] His Kinase A (phospho-acceptor) domain; [GO:0000155] phosphorelay sensor kinase activity 239.87 0.5106 193 Mapoly0041s0148 [PF01426] BAH domain; [GO:0003682] chromatin binding; [PTHR12505] PHD FINGER TRANSCRIPTION FACTOR 240.08 0.5871 194 Mapoly0039s0088 [KOG0978] E3 ubiquitin ligase involved in syntaxin degradation 240.17 0.5958 195 Mapoly0044s0131 [PF12937] F-box-like; [GO:0005515] protein binding; [PTHR23125] F-BOX/LEUCINE RICH REPEAT PROTEIN 242.30 0.5498 196 Mapoly0020s0146 - 244.27 0.5810 197 Mapoly0014s0032 [PTHR14873] FAMILY NOT NAMED; [PF10521] Protein of unknown function (DUF2454); [PTHR14873:SF1] SUBFAMILY NOT NAMED 244.75 0.5815 198 Mapoly0069s0084 [3.6.5.5] Dynamin GTPase.; [KOG0446] Vacuolar sorting protein VPS1, dynamin, and related proteins; [K01528] dynamin GTPase [EC:3.6.5.5]; [PF02212] Dynamin GTPase effector domain; [PF00350] Dynamin family; [PTHR11566] DYNAMIN; [GO:0003924] GTPase activity; [PTHR11566:SF21] SUBFAMILY NOT NAMED; [GO:0005525] GTP binding; [PF01031] Dynamin central region 247.83 0.5901 199 Mapoly0086s0053 - 247.88 0.5716 200 Mapoly0032s0133 [PF12432] Protein of unknown function (DUF3677); [PTHR21224:SF1] SUBFAMILY NOT NAMED; [K13138] integrator complex subunit 1; [PTHR21224] UNCHARACTERIZED 247.99 0.5814