Guide Gene

Gene ID
Mapoly0113s0020
Organism
Marchantia polymorpha
Platform ID
Mpo
Description
[GO:0003677] DNA binding; [PTHR12604:SF2] KU P70 DNA HELICASE; [K10884] ATP-dependent DNA helicase 2 subunit 1; [GO:0042162] telomeric DNA binding; [PF03730] Ku70/Ku80 C-terminal arm; [PF02735] Ku70/Ku80 beta-barrel domain; [PF03731] Ku70/Ku80 N-terminal alpha/beta domain; [GO:0043564] Ku70:Ku80 complex; [GO:0005634] nucleus; [GO:0004003] ATP-dependent DNA helicase activity; [GO:0003676] nucleic acid binding; [KOG2327] DNA-binding subunit of a DNA-dependent protein kinase (Ku70 autoantigen); [PTHR12604] KU AUTOANTIGEN DNA HELICASE; [GO:0003684] damaged DNA binding; [GO:0006303] double-strand break repair via nonhomologous end joining; [PF02037] SAP domain; [GO:0000723] telomere maintenance

Coexpressed Gene List

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Marchantia polymorpha
Rank Gene ID Description MR PCC
Guide Mapoly0113s0020 [GO:0003677] DNA binding; [PTHR12604:SF2] KU P70 DNA HELICASE; [K10884] ATP-dependent DNA helicase 2 subunit 1; [GO:0042162] telomeric DNA binding; [PF03730] Ku70/Ku80 C-terminal arm; [PF02735] Ku70/Ku80 beta-barrel domain; [PF03731] Ku70/Ku80 N-terminal alpha/beta domain; [GO:0043564] Ku70:Ku80 complex; [GO:0005634] nucleus; [GO:0004003] ATP-dependent DNA helicase activity; [GO:0003676] nucleic acid binding; [KOG2327] DNA-binding subunit of a DNA-dependent protein kinase (Ku70 autoantigen); [PTHR12604] KU AUTOANTIGEN DNA HELICASE; [GO:0003684] damaged DNA binding; [GO:0006303] double-strand break repair via nonhomologous end joining; [PF02037] SAP domain; [GO:0000723] telomere maintenance 0.00 1.0000
1 Mapoly0154s0015 [PF00645] Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region; [GO:0003677] DNA binding; [PTHR15447] POLY [ADP-RIBOSE] POLYMERASE; [GO:0003950] NAD+ ADP-ribosyltransferase activity; [PF05406] WGR domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0006471] protein ADP-ribosylation; [PF08063] PADR1 (NUC008) domain; [K10798] poly [ADP-ribose] polymerase [EC:2.4.2.30]; [GO:0005634] nucleus; [PF02877] Poly(ADP-ribose) polymerase, regulatory domain; [2.4.2.30] NAD(+) ADP-ribosyltransferase.; [KOG1037] NAD+ ADP-ribosyltransferase Parp, required for poly-ADP ribosylation of nuclear proteins; [PF00644] Poly(ADP-ribose) polymerase catalytic domain2.450.7815
2 Mapoly0114s0002 [PF03168] Late embryogenesis abundant protein; [PTHR31852] FAMILY NOT NAMED3.000.8067
3 Mapoly0086s0067 [GO:0005524] ATP binding; [GO:0032300] mismatch repair complex; [KOG1979] DNA mismatch repair protein - MLH1 family; [PTHR10073] DNA MISMATCH REPAIR PROTEIN (MLH, PMS, MUTL); [PTHR10073:SF12] DNA MISMATCH REPAIR PROTEIN MUTL; [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [K08734] DNA mismatch repair protein MLH1; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01119] DNA mismatch repair protein, C-terminal domain3.460.7531
4 Mapoly0097s0033 [PTHR10870] CELL CYCLE CHECKPOINT PROTEIN RAD1; [KOG3194] Checkpoint 9-1-1 complex, RAD1 component; [PF02144] Repair protein Rad1/Rec1/Rad17; [GO:0005634] nucleus; [K02830] cell cycle checkpoint protein [EC:3.1.11.2]; [GO:0006281] DNA repair; [3.1.11.2] Exodeoxyribonuclease III.8.370.7530
5 Mapoly0151s0042 [PTHR31500:SF0] SUBFAMILY NOT NAMED; [PF03479] Domain of unknown function (DUF296); [PTHR31500] FAMILY NOT NAMED11.400.7605
6 Mapoly0029s0099 [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PTHR23336:SF7] SUBFAMILY NOT NAMED; [KOG1845] MORC family ATPases; [PTHR23336] ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3.12.000.7629
7 Mapoly0004s0128 [GO:0005524] ATP binding; [K08864] tousled-like kinase [EC:2.7.11.1]; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PTHR22974] MIXED LINEAGE PROTEIN KINASE; [KOG1151] Tousled-like protein kinase12.370.7633
8 Mapoly0154s0010 -13.750.7470
9 Mapoly0021s0154 -14.280.7412
10 Mapoly0016s0052 [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat14.700.6963
11 Mapoly0004s0095 [KOG1303] Amino acid transporters; [PF01490] Transmembrane amino acid transporter protein; [PTHR22950] AMINO ACID TRANSPORTER14.830.7214
12 Mapoly0009s0203 -15.230.7501
13 Mapoly0007s0101 [PF09728] Myosin-like coiled-coil protein; [KOG1850] Myosin-like coiled-coil protein; [PTHR16127] TAXILIN; [GO:0019905] syntaxin binding16.310.7222
14 Mapoly0008s0026 [GO:0019773] proteasome core complex, alpha-subunit complex; [PTHR11599:SF14] PROTEASOME SUBUNIT ALPHA TYPE 5; [GO:0051603] proteolysis involved in cellular protein catabolic process; [KOG0176] 20S proteasome, regulatory subunit alpha type PSMA5/PUP2; [GO:0006511] ubiquitin-dependent protein catabolic process; [GO:0004175] endopeptidase activity; [GO:0004298] threonine-type endopeptidase activity; [PF10584] Proteasome subunit A N-terminal signature; [GO:0005839] proteasome core complex; [PF00227] Proteasome subunit; [PTHR11599] PROTEASOME SUBUNIT ALPHA/BETA16.730.7394
15 Mapoly0065s0033 [GO:0003723] RNA binding; [3.1.26.5] Ribonuclease P.; [K03538] ribonuclease P protein subunit POP4 [EC:3.1.26.5]; [GO:0000172] ribonuclease MRP complex; [PF01868] Domain of unknown function UPF0086; [PTHR13348] RIBONUCLEASE P; [GO:0006364] rRNA processing; [GO:0008033] tRNA processing; [GO:0030677] ribonuclease P complex; [GO:0006379] mRNA cleavage; [KOG4046] RNase MRP and P, subunit POP4/p29; [GO:0004540] ribonuclease activity17.750.7329
16 Mapoly0025s0110 -20.780.7255
17 Mapoly0055s0054 [PTHR13476] UNCHARACTERIZED; [PTHR13476:SF0] SUBFAMILY NOT NAMED; [PF09340] Histone acetyltransferase subunit NuA4; [K11344] chromatin modification-related protein EAF623.320.7291
18 Mapoly0187s0003 [PTHR22880] FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; [K06062] histone acetyltransferase [EC:2.3.1.48]; [GO:0005515] protein binding; [PF00439] Bromodomain; [GO:0008080] N-acetyltransferase activity; [PF00583] Acetyltransferase (GNAT) family; [2.3.1.48] Histone acetyltransferase.23.370.7395
19 Mapoly0011s0044 [K03132] transcription initiation factor TFIID subunit 7; [PF04658] TAFII55 protein conserved region; [PTHR12228] TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED; [GO:0005669] transcription factor TFIID complex; [GO:0006367] transcription initiation from RNA polymerase II promoter26.530.7186
20 Mapoly0033s0088 [GO:0005515] protein binding; [PTHR19918:SF8] gb def: Meiosis-specific APC/C activator protein AMA1 (Activator of meiotic APC/C protei; [KOG0305] Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits; [K03363] cell division cycle 20, cofactor of APC complex; [PTHR19918] CELL DIVISION CYCLE 20 (CDC20) (FIZZY)-RELATED; [PF00400] WD domain, G-beta repeat27.750.7437
21 Mapoly0015s0190 -32.740.7323
22 Mapoly0001s0551 [PF03470] XS zinc finger domain; [PTHR21596] RIBONUCLEASE P PROTEIN SUBUNIT P38-RELATED; [PF03469] XH domain; [PF03468] XS domain; [GO:0031047] gene silencing by RNA; [PTHR21596:SF3] TRANSCRIPTION FACTOR X1-LIKE32.860.7135
23 Mapoly0046s0105 [GO:0005097] Rab GTPase activator activity; [KOG2197] Ypt/Rab-specific GTPase-activating protein GYP7 and related proteins; [PTHR22957] TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN; [GO:0032313] regulation of Rab GTPase activity; [PF00566] Rab-GTPase-TBC domain32.860.7059
24 Mapoly0038s0101 [K12837] splicing factor U2AF 65 kDa subunit; [PTHR23139] RNA-BINDING PROTEIN; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG0120] Splicing factor U2AF, large subunit (RRM superfamily); [GO:0003676] nucleic acid binding; [PTHR23139:SF9] SPLICING FACTOR U2AF LARGE SUBUNIT; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)33.760.7438
25 Mapoly0079s0037 [PTHR21467] HEAT-LIKE REPEAT-CONTAINING PROTEIN; [KOG0211] Protein phosphatase 2A regulatory subunit A and related proteins35.330.7024
26 Mapoly0029s0009 [PF12313] NPR1/NIM1 like defence protein C terminal; [PF00651] BTB/POZ domain; [GO:0005515] protein binding; [PF12796] Ankyrin repeats (3 copies); [PTHR24198] ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN35.710.6795
27 Mapoly0158s0032 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [K10728] topoisomerase (DNA) II binding protein 1; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain38.370.7181
28 Mapoly0020s0153 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF00580] UvrD/REP helicase N-terminal domain; [PF13361] UvrD-like helicase C-terminal domain; [GO:0016787] hydrolase activity; [KOG2108] 3'-5' DNA helicase; [3.6.4.12] DNA helicase.; [K03657] DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12]; [GO:0004003] ATP-dependent DNA helicase activity; [PTHR11070] UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER38.540.7088
29 Mapoly0105s0026 -39.150.7213
30 Mapoly0090s0070 [PF00169] PH domain39.600.6832
31 Mapoly0061s0032 [GO:0016020] membrane; [PF07933] Protein of unknown function (DUF1681); [PTHR12847:SF4] SUBFAMILY NOT NAMED; [KOG2500] Uncharacterized conserved protein; [GO:0006897] endocytosis; [PTHR12847] ATP-BINDING CASSETTE (ABC) TRANSPORTER-RELATED40.150.7100
32 Mapoly0014s0032 [PTHR14873] FAMILY NOT NAMED; [PF10521] Protein of unknown function (DUF2454); [PTHR14873:SF1] SUBFAMILY NOT NAMED42.060.7060
33 Mapoly0097s0049 [GO:0000287] magnesium ion binding; [PF01397] Terpene synthase, N-terminal domain; [GO:0016829] lyase activity; [PF03936] Terpene synthase family, metal binding domain; [GO:0008152] metabolic process; [PTHR31739] FAMILY NOT NAMED; [GO:0010333] terpene synthase activity44.000.6431
34 Mapoly0163s0016 [PTHR31934] FAMILY NOT NAMED; [PF12697] Alpha/beta hydrolase family44.500.6896
35 Mapoly0059s0052 [KOG0331] ATP-dependent RNA helicase; [GO:0005524] ATP binding; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding45.300.6643
36 Mapoly0052s0068 [PTHR13271] UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE46.000.6869
37 Mapoly0067s0057 [GO:0016598] protein arginylation; [GO:0005524] ATP binding; [GO:0005737] cytoplasm; [GO:0000166] nucleotide binding; [KOG1193] Arginyl-tRNA-protein transferase; [PF04377] Arginine-tRNA-protein transferase, C terminus; [PF03485] Arginyl tRNA synthetase N terminal domain; [GO:0006420] arginyl-tRNA aminoacylation; [PTHR21367:SF0] SUBFAMILY NOT NAMED; [2.3.2.8] Arginyltransferase.; [GO:0004814] arginine-tRNA ligase activity; [K00685] arginine-tRNA-protein transferase [EC:2.3.2.8]; [GO:0004057] arginyltransferase activity; [PTHR21367] ARGININE-TRNA-PROTEIN TRANSFERASE 1; [PF04376] Arginine-tRNA-protein transferase, N terminus46.580.6742
38 Mapoly0003s0234 [PTHR23139] RNA-BINDING PROTEIN; [K13154] U11/U12 small nuclear ribonucleoprotein 31 kDa protein; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [KOG4206] Spliceosomal protein snRNP-U1A/U2B; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)47.560.6932
39 Mapoly0068s0006 -47.960.6553
40 Mapoly0033s0156 [KOG0266] WD40 repeat-containing protein; [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [PF00400] WD domain, G-beta repeat49.360.7088
41 Mapoly0131s0020 [KOG1010] Rb (Retinoblastoma tumor suppressor)-related protein; [PF01858] Retinoblastoma-associated protein A domain; [GO:0006357] regulation of transcription from RNA polymerase II promoter; [PF01857] Retinoblastoma-associated protein B domain; [GO:0005634] nucleus; [GO:0006351] transcription, DNA-dependent; [PF11934] Domain of unknown function (DUF3452); [GO:0051726] regulation of cell cycle; [PTHR13742] RETINOBLASTOMA-ASSOCIATED PROTEIN (RB)-RELATED; [GO:0007049] cell cycle53.900.6972
42 Mapoly0052s0071 [GO:0003951] NAD+ kinase activity; [KOG2178] Predicted sugar kinase; [2.7.1.23] NAD(+) kinase.; [GO:0006741] NADP biosynthetic process; [PTHR20275:SF0] SUBFAMILY NOT NAMED; [K00858] NAD+ kinase [EC:2.7.1.23]; [GO:0008152] metabolic process; [PTHR20275] FAMILY NOT NAMED; [PF01513] ATP-NAD kinase54.300.6712
43 Mapoly0046s0064 [PF01702] Queuine tRNA-ribosyltransferase; [2.4.2.29] tRNA-guanine(34) transglycosylase.; [GO:0008479] queuine tRNA-ribosyltransferase activity; [PTHR11962] QUEUINE TRNA-RIBOSYLTRANSFERASE; [GO:0008616] queuosine biosynthetic process; [K00773] queuine tRNA-ribosyltransferase [EC:2.4.2.29]; [GO:0006400] tRNA modification; [KOG3909] Queuine-tRNA ribosyltransferase54.330.6925
44 Mapoly0138s0027 [PTHR14845] FAMILY NOT NAMED; [GO:0036064] cilium basal body; [PTHR14845:SF0] SUBFAMILY NOT NAMED55.180.6566
45 Mapoly0056s0068 [GO:0004356] glutamate-ammonia ligase activity; [GO:0006542] glutamine biosynthetic process; [GO:0006807] nitrogen compound metabolic process; [K01915] glutamine synthetase [EC:6.3.1.2]; [PTHR20852] GLUTAMINE SYNTHETASE; [PF03951] Glutamine synthetase, beta-Grasp domain; [6.3.1.2] Glutamate--ammonia ligase.; [KOG0683] Glutamine synthetase; [PF00120] Glutamine synthetase, catalytic domain58.580.6728
46 Mapoly0027s0188 [GO:0035299] inositol pentakisphosphate 2-kinase activity; [GO:0005524] ATP binding; [PTHR14456] INOSITOL POLYPHOSPHATE KINASE 1; [PF06090] Inositol-pentakisphosphate 2-kinase; [KOG4749] Inositol polyphosphate kinase58.630.6119
47 Mapoly0076s0002 [PTHR14854] NIF3L1BP1 PROTEIN-RELATED; [KOG3215] Uncharacterized conserved protein; [GO:0000445] THO complex part of transcription export complex; [GO:0006397] mRNA processing; [K13176] THO complex subunit 7; [PF05615] Tho complex subunit 760.470.6777
48 Mapoly0019s0098 [PF13345] Domain of unknown function (DUF4098)60.620.6646
49 Mapoly0007s0152 [PTHR23147] SERINE/ARGININE RICH SPLICING FACTOR; [KOG4207] Predicted splicing factor, SR protein superfamily; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)60.790.6999
50 Mapoly0075s0037 [K03257] translation initiation factor eIF-4A; [GO:0005524] ATP binding; [KOG0328] Predicted ATP-dependent RNA helicase FAL1, involved in rRNA maturation, DEAD-box superfamily; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding60.970.6741
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