| 1 |
Mapoly0027s0186
| [GO:0005524] ATP binding; [K10866] DNA repair protein RAD50 [EC:3.6.-.-]; [PF13476] AAA domain; [GO:0008270] zinc ion binding; [PF04423] Rad50 zinc hook motif; [3.6.-.-] Acting on acid anhydrides.; [GO:0006281] DNA repair; [KOG0962] DNA repair protein RAD50, ABC-type ATPase/SMC superfamily; [PTHR18867:SF12] SUBFAMILY NOT NAMED; [PTHR18867] RAD50; [GO:0004518] nuclease activity; [GO:0030870] Mre11 complex; [PF13558] Putative exonuclease SbcCD, C subunit | 1.00 | 0.9099 |
| 2 |
Mapoly0011s0008
| [PTHR11254] HECT DOMAIN UBIQUITIN-PROTEIN LIGASE; [KOG0941] E3 ubiquitin protein ligase; [GO:0004842] ubiquitin-protein ligase activity; [PF00415] Regulator of chromosome condensation (RCC1) repeat; [PF00632] HECT-domain (ubiquitin-transferase) | 2.00 | 0.8353 |
| 3 |
Mapoly0015s0190
| - | 3.00 | 0.8369 |
| 4 |
Mapoly0003s0184
| [GO:0006396] RNA processing; [GO:0003677] DNA binding; [GO:0003723] RNA binding; [GO:0005524] ATP binding; [K11592] endoribonuclease Dicer [EC:3.1.26.-]; [PF02170] PAZ domain; [3.1.26.-] Endoribonucleases producing 5'-phosphomonoesters.; [PTHR14950] HELICASE-RELATED; [GO:0005515] protein binding; [GO:0016891] endoribonuclease activity, producing 5'-phosphomonoesters; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [PF03368] Dicer dimerisation domain; [PF00636] Ribonuclease III domain; [GO:0004525] ribonuclease III activity; [PF00271] Helicase conserved C-terminal domain; [PF14709] double strand RNA binding domain from DEAD END PROTEIN 1; [KOG0701] dsRNA-specific nuclease Dicer and related ribonucleases | 4.00 | 0.8520 |
| 5 |
Mapoly0080s0093
| [GO:0003677] DNA binding; [PF00046] Homeobox domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR12628] POLYCOMB-LIKE TRANSCRIPTION FACTOR | 7.00 | 0.8284 |
| 6 |
Mapoly0032s0133
| [PF12432] Protein of unknown function (DUF3677); [PTHR21224:SF1] SUBFAMILY NOT NAMED; [K13138] integrator complex subunit 1; [PTHR21224] UNCHARACTERIZED | 7.35 | 0.8340 |
| 7 |
Mapoly0007s0083
| - | 8.12 | 0.7733 |
| 8 |
Mapoly0070s0048
| [GO:0005665] DNA-directed RNA polymerase II, core complex; [PF04998] RNA polymerase Rpb1, domain 5; [GO:0003677] DNA binding; [PF00623] RNA polymerase Rpb1, domain 2; [PTHR19376] DNA-DIRECTED RNA POLYMERASE; [PF05000] RNA polymerase Rpb1, domain 4; [PF04990] RNA polymerase Rpb1, domain 7; [PF05001] RNA polymerase Rpb1 C-terminal repeat; [PF04997] RNA polymerase Rpb1, domain 1; [GO:0006351] transcription, DNA-dependent; [KOG0260] RNA polymerase II, large subunit; [GO:0006366] transcription from RNA polymerase II promoter; [GO:0003899] DNA-directed RNA polymerase activity; [K03006] DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]; [PF04983] RNA polymerase Rpb1, domain 3; [2.7.7.6] DNA-directed RNA polymerase.; [PF04992] RNA polymerase Rpb1, domain 6; [PTHR19376:SF33] DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'' | 10.82 | 0.8068 |
| 9 |
Mapoly0028s0110
| [GO:0005524] ATP binding; [PTHR23069] TAT-BINDING HOMOLOG 7; [PTHR23069:SF0] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [PF00439] Bromodomain; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0732] AAA+-type ATPase containing the bromodomain | 13.23 | 0.8348 |
| 10 |
Mapoly0120s0055
| [GO:0003677] DNA binding; [PTHR12486] APRATAXIN-RELATED; [PF13671] AAA domain; [PF01661] Macro domain; [GO:0006281] DNA repair; [KOG0562] Predicted hydrolase (HIT family); [PF11969] Scavenger mRNA decapping enzyme C-term binding; [GO:0033699] DNA 5'-adenosine monophosphate hydrolase activity; [PF10283] Zinc-finger (CX5CX6HX5H) motif; [3.-.-.-] Hydrolases.; [K10863] aprataxin [EC:3.-.-.-]; [PTHR12486:SF4] APRATAXIN (FORKHEAD-ASSOCIATED DOMAIN HISTIDINE-TRIAD LIKE PROTEIN) | 13.78 | 0.6530 |
| 11 |
Mapoly0143s0017
| - | 14.14 | 0.7899 |
| 12 |
Mapoly0005s0093
| [KOG1883] Cofactor required for Sp1 transcriptional activation, subunit 3; [PF11573] Mediator complex subunit 23; [PTHR12691] FAMILY NOT NAMED | 14.49 | 0.7934 |
| 13 |
Mapoly0010s0094
| [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [PF00454] Phosphatidylinositol 3- and 4-kinase; [KOG0889] Histone acetyltransferase SAGA, TRRAP/TRA1 component, PI-3 kinase superfamily; [PTHR11139:SF1] ATM-RELATED; [K08874] transformation/transcription domain-associated protein; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED | 16.00 | 0.8228 |
| 14 |
Mapoly0003s0033
| [GO:0003723] RNA binding; [2.7.7.19] Polynucleotide adenylyltransferase.; [GO:0043631] RNA polyadenylation; [PF04928] Poly(A) polymerase central domain; [GO:0004652] polynucleotide adenylyltransferase activity; [GO:0005634] nucleus; [PTHR10682] POLY(A) POLYMERASE; [PF04926] Poly(A) polymerase predicted RNA binding domain; [PF01909] Nucleotidyltransferase domain; [GO:0016779] nucleotidyltransferase activity; [KOG2245] Poly(A) polymerase and related nucleotidyltransferases; [K14376] poly(A) polymerase [EC:2.7.7.19] | 18.97 | 0.7327 |
| 15 |
Mapoly0054s0103
| [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [3.6.4.13] RNA helicase.; [KOG0923] mRNA splicing factor ATP-dependent RNA helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [PF07717] Oligonucleotide/oligosaccharide-binding (OB)-fold; [K12813] pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:3.6.4.13] | 18.97 | 0.8037 |
| 16 |
Mapoly0020s0153
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF00580] UvrD/REP helicase N-terminal domain; [PF13361] UvrD-like helicase C-terminal domain; [GO:0016787] hydrolase activity; [KOG2108] 3'-5' DNA helicase; [3.6.4.12] DNA helicase.; [K03657] DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12]; [GO:0004003] ATP-dependent DNA helicase activity; [PTHR11070] UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER | 21.17 | 0.7739 |
| 17 |
Mapoly0224s0007
| [PTHR12456] TOPOISOMERASE 1-BINDING RING FINGER-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [GO:0046872] metal ion binding | 21.63 | 0.7657 |
| 18 |
Mapoly0096s0011
| [PTHR12436] 80 KDA MCM3-ASSOCIATED PROTEIN; [PF03399] SAC3/GANP/Nin1/mts3/eIF-3 p25 family | 21.75 | 0.8023 |
| 19 |
Mapoly0080s0034
| [2.1.1.43] Histone-lysine N-methyltransferase.; [KOG1082] Histone H3 (Lys9) methyltransferase SUV39H1/Clr4, required for transcriptional silencing; [K11419] histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43]; [PF05033] Pre-SET motif; [GO:0005515] protein binding; [PF00856] SET domain; [GO:0008270] zinc ion binding; [GO:0018024] histone-lysine N-methyltransferase activity; [PTHR22884] SET DOMAIN PROTEINS; [GO:0005634] nucleus; [GO:0034968] histone lysine methylation; [PF13771] PHD-like zinc-binding domain | 22.98 | 0.7872 |
| 20 |
Mapoly0009s0011
| [PF06650] Protein of unknown function (DUF1162); [PTHR16166] VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN (VPS13); [PF12624] N-terminal region of Chorein, a TM vesicle-mediated sorter | 23.66 | 0.7967 |
| 21 |
Mapoly0048s0100
| [PTHR18937:SF8] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC3; [GO:0005524] ATP binding; [KOG0964] Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3); [GO:0008280] cohesin core heterodimer; [GO:0005515] protein binding; [GO:0003682] chromatin binding; [GO:0007064] mitotic sister chromatid cohesion; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain; [K06669] structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) | 24.37 | 0.7906 |
| 22 |
Mapoly0047s0119
| [KOG0891] DNA-dependent protein kinase; [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [PF08771] Rapamycin binding domain; [K07203] FKBP12-rapamycin complex-associated protein; [GO:0005515] protein binding; [GO:0008144] drug binding; [PF11865] Domain of unknown function (DUF3385); [PF00454] Phosphatidylinositol 3- and 4-kinase; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED | 24.74 | 0.8015 |
| 23 |
Mapoly0157s0010
| [GO:0003677] DNA binding; [GO:0016570] histone modification; [GO:0006352] DNA-dependent transcription, initiation; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0005515] protein binding; [PF03126] Plus-3 domain; [PTHR22884] SET DOMAIN PROTEINS; [PF02213] GYF domain; [GO:0005634] nucleus; [KOG1946] RNA polymerase I transcription factor UAF; [PF02201] SWIB/MDM2 domain; [GO:0046872] metal ion binding | 25.79 | 0.7905 |
| 24 |
Mapoly0104s0042
| [PTHR22846:SF2] TRANSDUCIN BETA-LIKE 1; [GO:0005515] protein binding; [PTHR22846] WD40 REPEAT PROTEIN; [KOG0273] Beta-transducin family (WD-40 repeat) protein; [PF08513] LisH; [PF00400] WD domain, G-beta repeat | 25.92 | 0.7932 |
| 25 |
Mapoly0069s0061
| [GO:0004677] DNA-dependent protein kinase activity; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [K06642] DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]; [PF08163] NUC194 domain; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0005634] nucleus; [PF00454] Phosphatidylinositol 3- and 4-kinase; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [GO:0006303] double-strand break repair via nonhomologous end joining | 26.72 | 0.7703 |
| 26 |
Mapoly0005s0201
| [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005515] protein binding; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PTHR12348] TSC22; [PF00498] FHA domain | 28.28 | 0.7802 |
| 27 |
Mapoly0026s0020
| [KOG2253] U1 snRNP complex, subunit SNU71 and related PWI-motif proteins | 29.15 | 0.7932 |
| 28 |
Mapoly0037s0026
| [PTHR15598] AUTOANTIGEN RCD8; [GO:0005515] protein binding; [KOG1916] Nuclear protein, contains WD40 repeats; [K12616] enhancer of mRNA-decapping protein 4; [PF00400] WD domain, G-beta repeat | 30.63 | 0.7361 |
| 29 |
Mapoly0054s0064
| [PF03178] CPSF A subunit region; [PF10433] Mono-functional DNA-alkylating methyl methanesulfonate N-term; [PTHR10644:SF3] DNA DAMAGE-BINDING PROTEIN 1 (DAMAGE-SPECIFIC DNA-BINDING PROTEIN 1)(UV-DAMAGED DNA-BINDING FACTOR); [K10610] DNA damage-binding protein 1; [GO:0005634] nucleus; [PTHR10644] DNA REPAIR/RNA PROCESSING CPSF FAMILY; [KOG1897] Damage-specific DNA binding complex, subunit DDB1; [GO:0003676] nucleic acid binding | 30.76 | 0.7176 |
| 30 |
Mapoly0001s0208
| [PTHR31431] FAMILY NOT NAMED; [KOG4833] Uncharacterized conserved protein; [K14311] nuclear pore complex protein Nup188; [PF10487] Nucleoporin subcomplex protein binding to Pom34 | 31.37 | 0.7862 |
| 31 |
Mapoly0014s0121
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0390] DNA repair protein, SNF2 family; [PF00271] Helicase conserved C-terminal domain | 31.43 | 0.7665 |
| 32 |
Mapoly0045s0119
| [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR13161] SPLICING FACTOR (SUPPRESSOR OF WHITE APRICOT); [PF01805] Surp module; [PF09750] Alternative splicing regulator; [KOG1847] mRNA splicing factor | 31.84 | 0.7785 |
| 33 |
Mapoly0002s0028
| [PF00630] Filamin/ABP280 repeat; [GO:0003676] nucleic acid binding; [KOG0146] RNA-binding protein ETR-3 (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 34.25 | 0.7863 |
| 34 |
Mapoly0001s0369
| [K12879] THO complex subunit 2; [PF11262] Transcription factor/nuclear export subunit protein 2; [PTHR21597] THO2 PROTEIN; [PF11732] Transcription- and export-related complex subunit; [PTHR21597:SF0] SUBFAMILY NOT NAMED; [KOG1874] KEKE-like motif-containing transcription regulator (Rlr1)/suppressor of sin4 | 34.58 | 0.7972 |
| 35 |
Mapoly0131s0020
| [KOG1010] Rb (Retinoblastoma tumor suppressor)-related protein; [PF01858] Retinoblastoma-associated protein A domain; [GO:0006357] regulation of transcription from RNA polymerase II promoter; [PF01857] Retinoblastoma-associated protein B domain; [GO:0005634] nucleus; [GO:0006351] transcription, DNA-dependent; [PF11934] Domain of unknown function (DUF3452); [GO:0051726] regulation of cell cycle; [PTHR13742] RETINOBLASTOMA-ASSOCIATED PROTEIN (RB)-RELATED; [GO:0007049] cell cycle | 35.71 | 0.7530 |
| 36 |
Mapoly0063s0041
| [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR23340] ARGININE/SERINE RICH SPLICING FACTOR SF4/14; [PF01585] G-patch domain; [GO:0003676] nucleic acid binding; [PF01805] Surp module | 36.50 | 0.7689 |
| 37 |
Mapoly0006s0222
| [GO:0005524] ATP binding; [GO:0032300] mismatch repair complex; [KOG1977] DNA mismatch repair protein - MLH3 family; [PTHR10073:SF7] DNA MISMATCH REPAIR PROTEIN MLH3; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [GO:0007131] reciprocal meiotic recombination; [PTHR10073] DNA MISMATCH REPAIR PROTEIN (MLH, PMS, MUTL); [GO:0006298] mismatch repair; [PF08676] MutL C terminal dimerisation domain; [GO:0030983] mismatched DNA binding; [PF01119] DNA mismatch repair protein, C-terminal domain; [K08739] DNA mismatch repair protein MLH3 | 37.79 | 0.7614 |
| 38 |
Mapoly0024s0008
| [GO:0003677] DNA binding; [KOG1793] Uncharacterized conserved protein; [PF08711] TFIIS helical bundle-like domain; [GO:0005634] nucleus; [GO:0006351] transcription, DNA-dependent; [PTHR22908] MIDASIN-RELATED | 37.96 | 0.6871 |
| 39 |
Mapoly0011s0132
| - | 39.42 | 0.7671 |
| 40 |
Mapoly0013s0109
| [PF00514] Armadillo/beta-catenin-like repeat; [PF00651] BTB/POZ domain; [GO:0005515] protein binding; [KOG0166] Karyopherin (importin) alpha; [PTHR23315] BETA CATENIN-RELATED ARMADILLO REPEAT-CONTAINING | 39.47 | 0.7619 |
| 41 |
Mapoly0116s0006
| [PF00651] BTB/POZ domain; [PF07707] BTB And C-terminal Kelch; [GO:0005515] protein binding; [PTHR23125] F-BOX/LEUCINE RICH REPEAT PROTEIN | 40.15 | 0.7391 |
| 42 |
Mapoly0153s0011
| [PF13871] Helicase_C-like; [GO:0006355] regulation of transcription, DNA-dependent; [KOG1513] Nuclear helicase MOP-3/SNO (DEAD-box superfamily); [PTHR12706] STRAWBERRY NOTCH-RELATED; [PF13872] P-loop containing NTP hydrolase pore-1 | 40.21 | 0.7887 |
| 43 |
Mapoly0084s0045
| [PF07719] Tetratricopeptide repeat; [KOG1211] Amidases; [PF13414] TPR repeat; [PTHR11895] AMIDASE; [GO:0016884] carbon-nitrogen ligase activity, with glutamine as amido-N-donor; [PTHR11895:SF6] AMIDASE; [PF01425] Amidase | 40.40 | 0.7348 |
| 44 |
Mapoly0079s0050
| [2.7.11.25] Mitogen-activated protein kinase kinase kinase.; [PF07714] Protein tyrosine kinase; [K04424] sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]; [KOG0192] Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs; [PTHR23257] SERINE-THREONINE PROTEIN KINASE; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PF14381] Ethylene-responsive protein kinase Le-CTR1 | 41.41 | 0.7541 |
| 45 |
Mapoly0025s0016
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00176] SNF2 family N-terminal domain; [PF00271] Helicase conserved C-terminal domain; [PF02178] AT hook motif; [KOG0383] Predicted helicase | 43.07 | 0.7693 |
| 46 |
Mapoly0033s0156
| [KOG0266] WD40 repeat-containing protein; [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [PF00400] WD domain, G-beta repeat | 43.47 | 0.7501 |
| 47 |
Mapoly0037s0036
| [GO:0005524] ATP binding; [PTHR23077:SF9] PEROXISOME ASSEMBLY FACTOR-2 (PEROXISOMAL-TYPE ATPASE 1); [KOG0736] Peroxisome assembly factor 2 containing the AAA+-type ATPase domain; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23077] AAA-FAMILY ATPASE; [K13339] peroxin-6 | 44.18 | 0.6273 |
| 48 |
Mapoly0001s0473
| - | 45.52 | 0.7770 |
| 49 |
Mapoly0162s0013
| [PF00929] Exonuclease; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [PTHR11361:SF34] DNA MISMATCH REPAIR PROTEIN MUTS; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [KOG0218] Mismatch repair MSH3; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV | 46.18 | 0.7773 |
| 50 |
Mapoly0014s0115
| [PTHR15137] TRANSCRIPTION INITIATION FACTOR TFIID; [PF01433] Peptidase family M1; [GO:0008237] metallopeptidase activity; [GO:0008270] zinc ion binding; [K03128] transcription initiation factor TFIID subunit 2; [KOG1932] TATA binding protein associated factor | 46.37 | 0.7539 |
