| 1 |
Mapoly0029s0152
| [PTHR15239] UNCHARACTERIZED; [PF05833] Fibronectin-binding protein A N-terminus (FbpA); [PTHR15239:SF1] COLON CANCER ANTIGEN 1; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding; [PF11923] Domain of unknown function (DUF3441); [KOG2030] Predicted RNA-binding protein; [PF05670] Domain of unknown function (DUF814) | 1.00 | 0.9099 |
| 2 |
Mapoly0028s0110
| [GO:0005524] ATP binding; [PTHR23069] TAT-BINDING HOMOLOG 7; [PTHR23069:SF0] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [PF00439] Bromodomain; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0732] AAA+-type ATPase containing the bromodomain | 2.00 | 0.9091 |
| 3 |
Mapoly0032s0133
| [PF12432] Protein of unknown function (DUF3677); [PTHR21224:SF1] SUBFAMILY NOT NAMED; [K13138] integrator complex subunit 1; [PTHR21224] UNCHARACTERIZED | 2.00 | 0.8861 |
| 4 |
Mapoly0003s0184
| [GO:0006396] RNA processing; [GO:0003677] DNA binding; [GO:0003723] RNA binding; [GO:0005524] ATP binding; [K11592] endoribonuclease Dicer [EC:3.1.26.-]; [PF02170] PAZ domain; [3.1.26.-] Endoribonucleases producing 5'-phosphomonoesters.; [PTHR14950] HELICASE-RELATED; [GO:0005515] protein binding; [GO:0016891] endoribonuclease activity, producing 5'-phosphomonoesters; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [PF03368] Dicer dimerisation domain; [PF00636] Ribonuclease III domain; [GO:0004525] ribonuclease III activity; [PF00271] Helicase conserved C-terminal domain; [PF14709] double strand RNA binding domain from DEAD END PROTEIN 1; [KOG0701] dsRNA-specific nuclease Dicer and related ribonucleases | 3.16 | 0.8733 |
| 5 |
Mapoly0080s0093
| [GO:0003677] DNA binding; [PF00046] Homeobox domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR12628] POLYCOMB-LIKE TRANSCRIPTION FACTOR | 3.74 | 0.8521 |
| 6 |
Mapoly0218s0012
| [PTHR15744:SF0] SUBFAMILY NOT NAMED; [PTHR15744] BLOM7 | 3.74 | 0.8672 |
| 7 |
Mapoly0026s0020
| [KOG2253] U1 snRNP complex, subunit SNU71 and related PWI-motif proteins | 3.87 | 0.8955 |
| 8 |
Mapoly0143s0017
| - | 4.58 | 0.8386 |
| 9 |
Mapoly0104s0042
| [PTHR22846:SF2] TRANSDUCIN BETA-LIKE 1; [GO:0005515] protein binding; [PTHR22846] WD40 REPEAT PROTEIN; [KOG0273] Beta-transducin family (WD-40 repeat) protein; [PF08513] LisH; [PF00400] WD domain, G-beta repeat | 5.66 | 0.8662 |
| 10 |
Mapoly0002s0028
| [PF00630] Filamin/ABP280 repeat; [GO:0003676] nucleic acid binding; [KOG0146] RNA-binding protein ETR-3 (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 6.93 | 0.8703 |
| 11 |
Mapoly0014s0115
| [PTHR15137] TRANSCRIPTION INITIATION FACTOR TFIID; [PF01433] Peptidase family M1; [GO:0008237] metallopeptidase activity; [GO:0008270] zinc ion binding; [K03128] transcription initiation factor TFIID subunit 2; [KOG1932] TATA binding protein associated factor | 7.75 | 0.8474 |
| 12 |
Mapoly0054s0103
| [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [3.6.4.13] RNA helicase.; [KOG0923] mRNA splicing factor ATP-dependent RNA helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [PF07717] Oligonucleotide/oligosaccharide-binding (OB)-fold; [K12813] pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:3.6.4.13] | 9.95 | 0.8551 |
| 13 |
Mapoly0001s0473
| - | 10.39 | 0.8644 |
| 14 |
Mapoly0080s0034
| [2.1.1.43] Histone-lysine N-methyltransferase.; [KOG1082] Histone H3 (Lys9) methyltransferase SUV39H1/Clr4, required for transcriptional silencing; [K11419] histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43]; [PF05033] Pre-SET motif; [GO:0005515] protein binding; [PF00856] SET domain; [GO:0008270] zinc ion binding; [GO:0018024] histone-lysine N-methyltransferase activity; [PTHR22884] SET DOMAIN PROTEINS; [GO:0005634] nucleus; [GO:0034968] histone lysine methylation; [PF13771] PHD-like zinc-binding domain | 10.58 | 0.8292 |
| 15 |
Mapoly0002s0236
| [PTHR10782:SF4] SUBFAMILY NOT NAMED; [PTHR10782] ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; [GO:0008270] zinc ion binding; [GO:0019789] SUMO ligase activity; [PF02891] MIZ/SP-RING zinc finger | 12.37 | 0.8450 |
| 16 |
Mapoly0003s0033
| [GO:0003723] RNA binding; [2.7.7.19] Polynucleotide adenylyltransferase.; [GO:0043631] RNA polyadenylation; [PF04928] Poly(A) polymerase central domain; [GO:0004652] polynucleotide adenylyltransferase activity; [GO:0005634] nucleus; [PTHR10682] POLY(A) POLYMERASE; [PF04926] Poly(A) polymerase predicted RNA binding domain; [PF01909] Nucleotidyltransferase domain; [GO:0016779] nucleotidyltransferase activity; [KOG2245] Poly(A) polymerase and related nucleotidyltransferases; [K14376] poly(A) polymerase [EC:2.7.7.19] | 12.41 | 0.7699 |
| 17 |
Mapoly0022s0041
| [GO:0003723] RNA binding; [KOG2190] PolyC-binding proteins alphaCP-1 and related KH domain proteins; [PTHR10288] KH DOMAIN CONTAINING RNA BINDING PROTEIN; [PF00013] KH domain | 12.65 | 0.8473 |
| 18 |
Mapoly0029s0108
| [PTHR10161] TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5; [K14379] tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]; [PF00149] Calcineurin-like phosphoesterase; [GO:0016787] hydrolase activity; [KOG2679] Purple (tartrate-resistant) acid phosphatase; [3.1.3.2] Acid phosphatase. | 13.04 | 0.8601 |
| 19 |
Mapoly0104s0019
| [KOG2242] Scaffold/matrix specific factor hnRNP-U/SAF-A, contains SPRY domain; [PTHR12381:SF13] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [PF13671] AAA domain; [PF00622] SPRY domain; [PTHR12381] RIBONUCLEOPROTEIN | 13.42 | 0.8412 |
| 20 |
Mapoly0010s0094
| [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [PF00454] Phosphatidylinositol 3- and 4-kinase; [KOG0889] Histone acetyltransferase SAGA, TRRAP/TRA1 component, PI-3 kinase superfamily; [PTHR11139:SF1] ATM-RELATED; [K08874] transformation/transcription domain-associated protein; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED | 14.42 | 0.8535 |
| 21 |
Mapoly0005s0067
| [PTHR15242:SF0] SUBFAMILY NOT NAMED; [PTHR15242] SPLICING FACTOR, ARGININE/SERINE-RICH 2,RNAP C-TERM INTERACTING PROTEIN; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding | 14.70 | 0.8543 |
| 22 |
Mapoly0006s0222
| [GO:0005524] ATP binding; [GO:0032300] mismatch repair complex; [KOG1977] DNA mismatch repair protein - MLH3 family; [PTHR10073:SF7] DNA MISMATCH REPAIR PROTEIN MLH3; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [GO:0007131] reciprocal meiotic recombination; [PTHR10073] DNA MISMATCH REPAIR PROTEIN (MLH, PMS, MUTL); [GO:0006298] mismatch repair; [PF08676] MutL C terminal dimerisation domain; [GO:0030983] mismatched DNA binding; [PF01119] DNA mismatch repair protein, C-terminal domain; [K08739] DNA mismatch repair protein MLH3 | 14.70 | 0.8307 |
| 23 |
Mapoly0007s0083
| - | 14.90 | 0.7712 |
| 24 |
Mapoly0030s0061
| [GO:0005663] DNA replication factor C complex; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [GO:0003689] DNA clamp loader activity; [PF00533] BRCA1 C Terminus (BRCT) domain; [K10754] replication factor C subunit 1; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08519] Replication factor RFC1 C terminal domain; [KOG1968] Replication factor C, subunit RFC1 (large subunit) | 15.00 | 0.8352 |
| 25 |
Mapoly0005s0201
| [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005515] protein binding; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PTHR12348] TSC22; [PF00498] FHA domain | 16.25 | 0.8379 |
| 26 |
Mapoly0048s0100
| [PTHR18937:SF8] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC3; [GO:0005524] ATP binding; [KOG0964] Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3); [GO:0008280] cohesin core heterodimer; [GO:0005515] protein binding; [GO:0003682] chromatin binding; [GO:0007064] mitotic sister chromatid cohesion; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain; [K06669] structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) | 16.91 | 0.8326 |
| 27 |
Mapoly0045s0119
| [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR13161] SPLICING FACTOR (SUPPRESSOR OF WHITE APRICOT); [PF01805] Surp module; [PF09750] Alternative splicing regulator; [KOG1847] mRNA splicing factor | 17.29 | 0.8372 |
| 28 |
Mapoly0015s0190
| - | 17.75 | 0.8212 |
| 29 |
Mapoly0046s0006
| - | 18.22 | 0.7021 |
| 30 |
Mapoly0107s0024
| [GO:0005524] ATP binding; [GO:0046982] protein heterodimerization activity; [KOG0018] Structural maintenance of chromosome protein 1 (sister chromatid cohesion complex Cohesin, subunit SMC1); [GO:0005515] protein binding; [GO:0003682] chromatin binding; [PTHR18937:SF12] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC1; [GO:0007064] mitotic sister chromatid cohesion; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0008278] cohesin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain; [K06636] structural maintenance of chromosome 1 | 18.65 | 0.8277 |
| 31 |
Mapoly0148s0032
| [PF01480] PWI domain; [PTHR18806:SF4] SUBFAMILY NOT NAMED; [GO:0006397] mRNA processing; [PTHR18806] RBM25 PROTEIN; [GO:0003676] nucleic acid binding; [K12822] RNA-binding protein 25; [KOG2253] U1 snRNP complex, subunit SNU71 and related PWI-motif proteins; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 18.97 | 0.8449 |
| 32 |
Mapoly0007s0143
| [KOG2235] Uncharacterized conserved protein; [PTHR31057] FAMILY NOT NAMED; [PF09743] Uncharacterized conserved protein (DUF2042); [PTHR31057:SF0] SUBFAMILY NOT NAMED | 19.44 | 0.7907 |
| 33 |
Mapoly0157s0010
| [GO:0003677] DNA binding; [GO:0016570] histone modification; [GO:0006352] DNA-dependent transcription, initiation; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0005515] protein binding; [PF03126] Plus-3 domain; [PTHR22884] SET DOMAIN PROTEINS; [PF02213] GYF domain; [GO:0005634] nucleus; [KOG1946] RNA polymerase I transcription factor UAF; [PF02201] SWIB/MDM2 domain; [GO:0046872] metal ion binding | 21.82 | 0.8227 |
| 34 |
Mapoly0096s0011
| [PTHR12436] 80 KDA MCM3-ASSOCIATED PROTEIN; [PF03399] SAC3/GANP/Nin1/mts3/eIF-3 p25 family | 21.91 | 0.8368 |
| 35 |
Mapoly0033s0088
| [GO:0005515] protein binding; [PTHR19918:SF8] gb def: Meiosis-specific APC/C activator protein AMA1 (Activator of meiotic APC/C protei; [KOG0305] Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits; [K03363] cell division cycle 20, cofactor of APC complex; [PTHR19918] CELL DIVISION CYCLE 20 (CDC20) (FIZZY)-RELATED; [PF00400] WD domain, G-beta repeat | 23.24 | 0.8198 |
| 36 |
Mapoly0004s0120
| [PF04998] RNA polymerase Rpb1, domain 5; [GO:0003677] DNA binding; [PF00623] RNA polymerase Rpb1, domain 2; [PTHR19376] DNA-DIRECTED RNA POLYMERASE; [PF05000] RNA polymerase Rpb1, domain 4; [PF11523] Protein of unknown function (DUF3223); [PF04997] RNA polymerase Rpb1, domain 1; [GO:0006351] transcription, DNA-dependent; [GO:0003899] DNA-directed RNA polymerase activity; [PF04983] RNA polymerase Rpb1, domain 3; [KOG0261] RNA polymerase III, large subunit; [PTHR19376:SF33] DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'' | 23.66 | 0.8094 |
| 37 |
Mapoly0224s0007
| [PTHR12456] TOPOISOMERASE 1-BINDING RING FINGER-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [GO:0046872] metal ion binding | 23.83 | 0.7730 |
| 38 |
Mapoly0005s0093
| [KOG1883] Cofactor required for Sp1 transcriptional activation, subunit 3; [PF11573] Mediator complex subunit 23; [PTHR12691] FAMILY NOT NAMED | 24.25 | 0.7998 |
| 39 |
Mapoly0135s0035
| [GO:0003676] nucleic acid binding; [PF02037] SAP domain | 24.27 | 0.8263 |
| 40 |
Mapoly0143s0016
| - | 25.34 | 0.7402 |
| 41 |
Mapoly0181s0006
| [PF13414] TPR repeat; [PTHR14699:SF0] SUBFAMILY NOT NAMED; [PTHR14699] STI2 PROTEIN-RELATED | 25.38 | 0.8014 |
| 42 |
Mapoly0043s0127
| [GO:0031625] ubiquitin protein ligase binding; [GO:0031461] cullin-RING ubiquitin ligase complex; [GO:0006511] ubiquitin-dependent protein catabolic process; [K10609] cullin 4; [PF10557] Cullin protein neddylation domain; [PTHR11932] CULLIN; [PF00888] Cullin family; [KOG2167] Cullins; [PTHR11932:SF27] SUBFAMILY NOT NAMED | 26.00 | 0.7919 |
| 43 |
Mapoly0033s0129
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0003910] DNA ligase (ATP) activity; [PF04679] ATP dependent DNA ligase C terminal region; [PTHR10459] DNA LIGASE; [K10747] DNA ligase 1 [EC:6.5.1.1]; [PF01068] ATP dependent DNA ligase domain; [6.5.1.1] DNA ligase (ATP).; [GO:0006281] DNA repair; [PF04675] DNA ligase N terminus; [PTHR10459:SF10] DNA LIGASE I; [GO:0006310] DNA recombination; [KOG0967] ATP-dependent DNA ligase I | 28.98 | 0.7736 |
| 44 |
Mapoly0021s0043
| - | 29.29 | 0.8100 |
| 45 |
Mapoly0001s0369
| [K12879] THO complex subunit 2; [PF11262] Transcription factor/nuclear export subunit protein 2; [PTHR21597] THO2 PROTEIN; [PF11732] Transcription- and export-related complex subunit; [PTHR21597:SF0] SUBFAMILY NOT NAMED; [KOG1874] KEKE-like motif-containing transcription regulator (Rlr1)/suppressor of sin4 | 29.88 | 0.8418 |
| 46 |
Mapoly0004s0038
| [PF10440] Ubiquitin-binding WIYLD domain; [KOG1082] Histone H3 (Lys9) methyltransferase SUV39H1/Clr4, required for transcriptional silencing; [PF05033] Pre-SET motif; [GO:0005515] protein binding; [PF00856] SET domain; [GO:0008270] zinc ion binding; [PTHR22884:SF23] SET DOMAIN PROTEIN; [GO:0018024] histone-lysine N-methyltransferase activity; [PTHR22884] SET DOMAIN PROTEINS; [GO:0005634] nucleus; [GO:0034968] histone lysine methylation | 30.40 | 0.7276 |
| 47 |
Mapoly0162s0013
| [PF00929] Exonuclease; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [PTHR11361:SF34] DNA MISMATCH REPAIR PROTEIN MUTS; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [KOG0218] Mismatch repair MSH3; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV | 30.46 | 0.8239 |
| 48 |
Mapoly0084s0051
| [2.1.1.43] Histone-lysine N-methyltransferase.; [GO:0005515] protein binding; [PF00856] SET domain; [KOG1079] Transcriptional repressor EZH1; [PTHR22884] SET DOMAIN PROTEINS; [K11430] enhancer of zeste [EC:2.1.1.43] | 30.98 | 0.7812 |
| 49 |
Mapoly0015s0206
| [PF05236] Transcription initiation factor TFIID component TAF4 family; [GO:0006352] DNA-dependent transcription, initiation; [PTHR15138] FAMILY NOT NAMED; [PF12174] RCD1-SRO-TAF4 (RST) plant domain; [GO:0005669] transcription factor TFIID complex | 31.43 | 0.8106 |
| 50 |
Mapoly0027s0147
| [PTHR12585] SCC1 / RAD21 FAMILY MEMBER; [PF04824] Conserved region of Rad21 / Rec8 like protein; [GO:0005515] protein binding; [PF04825] N terminus of Rad21 / Rec8 like protein; [K06670] cohesin complex subunit SCC1; [GO:0000228] nuclear chromosome; [KOG1213] Sister chromatid cohesion complex Cohesin, subunit RAD21/SCC1 | 31.61 | 0.8123 |
