Guide Gene
- Gene ID
- Mapoly0054s0103
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [3.6.4.13] RNA helicase.; [KOG0923] mRNA splicing factor ATP-dependent RNA helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [PF07717] Oligonucleotide/oligosaccharide-binding (OB)-fold; [K12813] pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:3.6.4.13]
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0054s0103 [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [3.6.4.13] RNA helicase.; [KOG0923] mRNA splicing factor ATP-dependent RNA helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [PF07717] Oligonucleotide/oligosaccharide-binding (OB)-fold; [K12813] pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:3.6.4.13] 0.00 1.0000 1 Mapoly0096s0011 [PTHR12436] 80 KDA MCM3-ASSOCIATED PROTEIN; [PF03399] SAC3/GANP/Nin1/mts3/eIF-3 p25 family 1.41 0.8961 2 Mapoly0063s0006 [KOG2217] U4/U6.U5 snRNP associated protein; [K11984] U4/U6.U5 tri-snRNP-associated protein 1; [PTHR14152:SF5] SUBFAMILY NOT NAMED; [PTHR14152] SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES; [PF03343] SART-1 family 3.46 0.8678 3 Mapoly0002s0028 [PF00630] Filamin/ABP280 repeat; [GO:0003676] nucleic acid binding; [KOG0146] RNA-binding protein ETR-3 (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 4.24 0.8830 4 Mapoly0029s0108 [PTHR10161] TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5; [K14379] tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]; [PF00149] Calcineurin-like phosphoesterase; [GO:0016787] hydrolase activity; [KOG2679] Purple (tartrate-resistant) acid phosphatase; [3.1.3.2] Acid phosphatase. 4.47 0.8821 5 Mapoly0001s0369 [K12879] THO complex subunit 2; [PF11262] Transcription factor/nuclear export subunit protein 2; [PTHR21597] THO2 PROTEIN; [PF11732] Transcription- and export-related complex subunit; [PTHR21597:SF0] SUBFAMILY NOT NAMED; [KOG1874] KEKE-like motif-containing transcription regulator (Rlr1)/suppressor of sin4 5.10 0.8919 6 Mapoly0224s0007 [PTHR12456] TOPOISOMERASE 1-BINDING RING FINGER-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [GO:0046872] metal ion binding 5.48 0.8096 7 Mapoly0148s0032 [PF01480] PWI domain; [PTHR18806:SF4] SUBFAMILY NOT NAMED; [GO:0006397] mRNA processing; [PTHR18806] RBM25 PROTEIN; [GO:0003676] nucleic acid binding; [K12822] RNA-binding protein 25; [KOG2253] U1 snRNP complex, subunit SNU71 and related PWI-motif proteins; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 6.32 0.8741 8 Mapoly0112s0032 [KOG2652] RNA polymerase II transcription initiation factor TFIIA, large chain; [PTHR12694] TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; [PTHR12694:SF8] TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; [PF03153] Transcription factor IIA, alpha/beta subunit; [GO:0005672] transcription factor TFIIA complex; [K03122] transcription initiation factor TFIIA large subunit; [GO:0006367] transcription initiation from RNA polymerase II promoter 6.86 0.7895 9 Mapoly0153s0011 [PF13871] Helicase_C-like; [GO:0006355] regulation of transcription, DNA-dependent; [KOG1513] Nuclear helicase MOP-3/SNO (DEAD-box superfamily); [PTHR12706] STRAWBERRY NOTCH-RELATED; [PF13872] P-loop containing NTP hydrolase pore-1 7.48 0.8624 10 Mapoly0103s0005 [PTHR32059] FAMILY NOT NAMED; [GO:0005515] protein binding; [PTHR32059:SF0] SUBFAMILY NOT NAMED; [PF02985] HEAT repeat; [KOG0211] Protein phosphatase 2A regulatory subunit A and related proteins 8.12 0.8056 11 Mapoly0027s0186 [GO:0005524] ATP binding; [K10866] DNA repair protein RAD50 [EC:3.6.-.-]; [PF13476] AAA domain; [GO:0008270] zinc ion binding; [PF04423] Rad50 zinc hook motif; [3.6.-.-] Acting on acid anhydrides.; [GO:0006281] DNA repair; [KOG0962] DNA repair protein RAD50, ABC-type ATPase/SMC superfamily; [PTHR18867:SF12] SUBFAMILY NOT NAMED; [PTHR18867] RAD50; [GO:0004518] nuclease activity; [GO:0030870] Mre11 complex; [PF13558] Putative exonuclease SbcCD, C subunit 9.95 0.8551 12 Mapoly0068s0038 [PTHR13413] YLP MOTIF CONTAINING PROTEIN (NUCLEAR PROTEIN ZAP); [PTHR13413:SF0] SUBFAMILY NOT NAMED; [GO:0005634] nucleus 11.49 0.8521 13 Mapoly0048s0033 [PTHR23079] RNA-DEPENDENT RNA POLYMERASE; [GO:0003968] RNA-directed RNA polymerase activity; [KOG0988] RNA-directed RNA polymerase QDE-1 required for posttranscriptional gene silencing and RNA interference; [PF05183] RNA dependent RNA polymerase 12.37 0.7167 14 Mapoly0026s0020 [KOG2253] U1 snRNP complex, subunit SNU71 and related PWI-motif proteins 12.85 0.8540 15 Mapoly0051s0016 [PF13831] PHD-finger; [PF05964] F/Y-rich N-terminus; [GO:0005515] protein binding; [PF13832] PHD-zinc-finger like domain; [PF00856] SET domain; [PTHR13793] PHD FINGER PROTEINS; [PF00855] PWWP domain; [GO:0005634] nucleus; [PF05965] F/Y rich C-terminus 13.56 0.8592 16 Mapoly0005s0067 [PTHR15242:SF0] SUBFAMILY NOT NAMED; [PTHR15242] SPLICING FACTOR, ARGININE/SERINE-RICH 2,RNAP C-TERM INTERACTING PROTEIN; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 13.78 0.8542 17 Mapoly0069s0088 - 13.86 0.7721 18 Mapoly0015s0206 [PF05236] Transcription initiation factor TFIID component TAF4 family; [GO:0006352] DNA-dependent transcription, initiation; [PTHR15138] FAMILY NOT NAMED; [PF12174] RCD1-SRO-TAF4 (RST) plant domain; [GO:0005669] transcription factor TFIID complex 15.30 0.8315 19 Mapoly0003s0184 [GO:0006396] RNA processing; [GO:0003677] DNA binding; [GO:0003723] RNA binding; [GO:0005524] ATP binding; [K11592] endoribonuclease Dicer [EC:3.1.26.-]; [PF02170] PAZ domain; [3.1.26.-] Endoribonucleases producing 5'-phosphomonoesters.; [PTHR14950] HELICASE-RELATED; [GO:0005515] protein binding; [GO:0016891] endoribonuclease activity, producing 5'-phosphomonoesters; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [PF03368] Dicer dimerisation domain; [PF00636] Ribonuclease III domain; [GO:0004525] ribonuclease III activity; [PF00271] Helicase conserved C-terminal domain; [PF14709] double strand RNA binding domain from DEAD END PROTEIN 1; [KOG0701] dsRNA-specific nuclease Dicer and related ribonucleases 15.97 0.8327 20 Mapoly0047s0119 [KOG0891] DNA-dependent protein kinase; [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [PF08771] Rapamycin binding domain; [K07203] FKBP12-rapamycin complex-associated protein; [GO:0005515] protein binding; [GO:0008144] drug binding; [PF11865] Domain of unknown function (DUF3385); [PF00454] Phosphatidylinositol 3- and 4-kinase; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED 15.97 0.8397 21 Mapoly0080s0093 [GO:0003677] DNA binding; [PF00046] Homeobox domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR12628] POLYCOMB-LIKE TRANSCRIPTION FACTOR 17.66 0.8186 22 Mapoly0036s0123 [GO:0000922] spindle pole; [PTHR19302:SF13] GAMMA-TUBULIN COMPLEX COMPONENT 2 (GCP-2); [PF04130] Spc97 / Spc98 family; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [KOG2001] Gamma-tubulin complex, DGRIP84/SPC97 component 18.33 0.8466 23 Mapoly0028s0110 [GO:0005524] ATP binding; [PTHR23069] TAT-BINDING HOMOLOG 7; [PTHR23069:SF0] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [PF00439] Bromodomain; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0732] AAA+-type ATPase containing the bromodomain 18.73 0.8470 24 Mapoly0029s0152 [PTHR15239] UNCHARACTERIZED; [PF05833] Fibronectin-binding protein A N-terminus (FbpA); [PTHR15239:SF1] COLON CANCER ANTIGEN 1; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding; [PF11923] Domain of unknown function (DUF3441); [KOG2030] Predicted RNA-binding protein; [PF05670] Domain of unknown function (DUF814) 18.97 0.8037 25 Mapoly0048s0100 [PTHR18937:SF8] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC3; [GO:0005524] ATP binding; [KOG0964] Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3); [GO:0008280] cohesin core heterodimer; [GO:0005515] protein binding; [GO:0003682] chromatin binding; [GO:0007064] mitotic sister chromatid cohesion; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain; [K06669] structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) 19.18 0.8205 26 Mapoly0027s0147 [PTHR12585] SCC1 / RAD21 FAMILY MEMBER; [PF04824] Conserved region of Rad21 / Rec8 like protein; [GO:0005515] protein binding; [PF04825] N terminus of Rad21 / Rec8 like protein; [K06670] cohesin complex subunit SCC1; [GO:0000228] nuclear chromosome; [KOG1213] Sister chromatid cohesion complex Cohesin, subunit RAD21/SCC1 19.90 0.8287 27 Mapoly0162s0013 [PF00929] Exonuclease; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [PTHR11361:SF34] DNA MISMATCH REPAIR PROTEIN MUTS; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [KOG0218] Mismatch repair MSH3; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 22.45 0.8292 28 Mapoly0105s0028 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 22.65 0.8149 29 Mapoly0005s0121 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG0154] RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains; [PF01585] G-patch domain; [K13094] RNA-binding protein 5/10; [PTHR13948] RNA-BINDING PROTEIN; [GO:0003676] nucleic acid binding; [PTHR13948:SF3] RNA-BINDING PROTEIN; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 22.91 0.8180 30 Mapoly0157s0010 [GO:0003677] DNA binding; [GO:0016570] histone modification; [GO:0006352] DNA-dependent transcription, initiation; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0005515] protein binding; [PF03126] Plus-3 domain; [PTHR22884] SET DOMAIN PROTEINS; [PF02213] GYF domain; [GO:0005634] nucleus; [KOG1946] RNA polymerase I transcription factor UAF; [PF02201] SWIB/MDM2 domain; [GO:0046872] metal ion binding 24.25 0.8125 31 Mapoly0107s0053 [GO:0008601] protein phosphatase type 2A regulator activity; [PTHR10257] SERINE/THREONINE PROTEIN PHOSPHATASE 2A (PP2A) REGULATORY SUBUNIT B; [GO:0000159] protein phosphatase type 2A complex; [KOG2085] Serine/threonine protein phosphatase 2A, regulatory subunit; [GO:0007165] signal transduction; [K11584] protein phosphatase 2 (formerly 2A), regulatory subunit B'; [PF01603] Protein phosphatase 2A regulatory B subunit (B56 family) 24.54 0.7912 32 Mapoly0001s0206 [KOG2073] SAP family cell cycle dependent phosphatase-associated protein; [PTHR12634:SF8] SUBFAMILY NOT NAMED; [PF04499] SIT4 phosphatase-associated protein; [PTHR12634] SIT4(YEAST)-ASSOCIATING PROTEIN-RELATED 25.22 0.7818 33 Mapoly0131s0010 [PTHR15921:SF3] SUBFAMILY NOT NAMED; [KOG2071] mRNA cleavage and polyadenylation factor I/II complex, subunit Pcf11; [PF04818] RNA polymerase II-binding domain.; [PTHR15921] PRE-MRNA CLEAVAGE COMPLEX II 25.61 0.8380 34 Mapoly0004s0286 [PTHR12663:SF0] SUBFAMILY NOT NAMED; [K11267] sister chromatid cohesion protein PDS5; [PTHR12663] ANDROGEN INDUCED INHIBITOR OF PROLIFERATION (AS3) / PDS5-RELATED; [KOG1525] Sister chromatid cohesion complex Cohesin, subunit PDS5 26.51 0.8315 35 Mapoly0007s0083 - 26.72 0.7458 36 Mapoly0104s0019 [KOG2242] Scaffold/matrix specific factor hnRNP-U/SAF-A, contains SPRY domain; [PTHR12381:SF13] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [PF13671] AAA domain; [PF00622] SPRY domain; [PTHR12381] RIBONUCLEOPROTEIN 29.73 0.8047 37 Mapoly0032s0123 [PTHR13484] FIP1-LIKE 1 PROTEIN; [PF05182] Fip1 motif; [KOG2812] Uncharacterized conserved protein 30.46 0.8062 38 Mapoly0032s0133 [PF12432] Protein of unknown function (DUF3677); [PTHR21224:SF1] SUBFAMILY NOT NAMED; [K13138] integrator complex subunit 1; [PTHR21224] UNCHARACTERIZED 31.30 0.8043 39 Mapoly0111s0052 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [KOG1015] Transcription regulator XNP/ATRX, DEAD-box superfamily; [K11681] helicase SWR1 [EC:3.6.4.12]; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [3.6.4.12] DNA helicase.; [PF00271] Helicase conserved C-terminal domain; [PF07529] HSA; [PF13921] Myb-like DNA-binding domain 31.30 0.8299 40 Mapoly0099s0003 [GO:0000922] spindle pole; [PF04130] Spc97 / Spc98 family; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN 31.62 0.7848 41 Mapoly0123s0029 [PTHR23188] FAMILY NOT NAMED; [KOG2478] Putative RNA polymerase II regulator; [PF03985] Paf1 32.40 0.7672 42 Mapoly0114s0035 [PTHR31169] FAMILY NOT NAMED; [PF10497] Zinc-finger domain of monoamine-oxidase A repressor R1 32.73 0.7834 43 Mapoly0033s0129 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0003910] DNA ligase (ATP) activity; [PF04679] ATP dependent DNA ligase C terminal region; [PTHR10459] DNA LIGASE; [K10747] DNA ligase 1 [EC:6.5.1.1]; [PF01068] ATP dependent DNA ligase domain; [6.5.1.1] DNA ligase (ATP).; [GO:0006281] DNA repair; [PF04675] DNA ligase N terminus; [PTHR10459:SF10] DNA LIGASE I; [GO:0006310] DNA recombination; [KOG0967] ATP-dependent DNA ligase I 33.23 0.7680 44 Mapoly0005s0048 [K14328] regulator of nonsense transcripts 3; [PTHR13112:SF0] SUBFAMILY NOT NAMED; [PTHR13112] UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN; [PF03467] Smg-4/UPF3 family 34.63 0.7420 45 Mapoly0061s0069 [K09422] myb proto-oncogene protein, plant; [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding; [PF13921] Myb-like DNA-binding domain 35.20 0.7775 46 Mapoly0070s0048 [GO:0005665] DNA-directed RNA polymerase II, core complex; [PF04998] RNA polymerase Rpb1, domain 5; [GO:0003677] DNA binding; [PF00623] RNA polymerase Rpb1, domain 2; [PTHR19376] DNA-DIRECTED RNA POLYMERASE; [PF05000] RNA polymerase Rpb1, domain 4; [PF04990] RNA polymerase Rpb1, domain 7; [PF05001] RNA polymerase Rpb1 C-terminal repeat; [PF04997] RNA polymerase Rpb1, domain 1; [GO:0006351] transcription, DNA-dependent; [KOG0260] RNA polymerase II, large subunit; [GO:0006366] transcription from RNA polymerase II promoter; [GO:0003899] DNA-directed RNA polymerase activity; [K03006] DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]; [PF04983] RNA polymerase Rpb1, domain 3; [2.7.7.6] DNA-directed RNA polymerase.; [PF04992] RNA polymerase Rpb1, domain 6; [PTHR19376:SF33] DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'' 36.66 0.7871 47 Mapoly0011s0008 [PTHR11254] HECT DOMAIN UBIQUITIN-PROTEIN LIGASE; [KOG0941] E3 ubiquitin protein ligase; [GO:0004842] ubiquitin-protein ligase activity; [PF00415] Regulator of chromosome condensation (RCC1) repeat; [PF00632] HECT-domain (ubiquitin-transferase) 37.79 0.7573 48 Mapoly0069s0084 [3.6.5.5] Dynamin GTPase.; [KOG0446] Vacuolar sorting protein VPS1, dynamin, and related proteins; [K01528] dynamin GTPase [EC:3.6.5.5]; [PF02212] Dynamin GTPase effector domain; [PF00350] Dynamin family; [PTHR11566] DYNAMIN; [GO:0003924] GTPase activity; [PTHR11566:SF21] SUBFAMILY NOT NAMED; [GO:0005525] GTP binding; [PF01031] Dynamin central region 37.95 0.7626 49 Mapoly0005s0070 [PF05623] Protein of unknown function (DUF789); [PTHR32010] FAMILY NOT NAMED 38.83 0.8167 50 Mapoly0011s0209 - 38.96 0.7696 51 Mapoly0094s0033 [GO:0016567] protein ubiquitination; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [KOG0314] Predicted E3 ubiquitin ligase; [GO:0005634] nucleus; [PF08783] DWNN domain; [GO:0003676] nucleic acid binding; [GO:0004842] ubiquitin-protein ligase activity; [PTHR15439] RETINOBLASTOMA-BINDING PROTEIN 6; [PF04564] U-box domain 39.24 0.7251 52 Mapoly0022s0041 [GO:0003723] RNA binding; [KOG2190] PolyC-binding proteins alphaCP-1 and related KH domain proteins; [PTHR10288] KH DOMAIN CONTAINING RNA BINDING PROTEIN; [PF00013] KH domain 39.42 0.8018 53 Mapoly0009s0011 [PF06650] Protein of unknown function (DUF1162); [PTHR16166] VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN (VPS13); [PF12624] N-terminal region of Chorein, a TM vesicle-mediated sorter 39.50 0.7969 54 Mapoly0002s0236 [PTHR10782:SF4] SUBFAMILY NOT NAMED; [PTHR10782] ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; [GO:0008270] zinc ion binding; [GO:0019789] SUMO ligase activity; [PF02891] MIZ/SP-RING zinc finger 40.12 0.7901 55 Mapoly0008s0250 [PTHR24007] BRCA1-ASSOCIATED PROTEIN; [PF00917] MATH domain; [GO:0005515] protein binding; [GO:0006281] DNA repair; [PF14631] Fanconi anaemia protein FancD2 nuclease; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 40.30 0.7799 56 Mapoly0042s0082 [GO:0005643] nuclear pore; [PF07926] TPR/MLP1/MLP2-like protein; [PTHR18898] NUCLEOPROTEIN TPR-RELATED; [K09291] nucleoprotein TPR; [KOG4674] Uncharacterized conserved coiled-coil protein; [GO:0006606] protein import into nucleus 41.36 0.8105 57 Mapoly0025s0016 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00176] SNF2 family N-terminal domain; [PF00271] Helicase conserved C-terminal domain; [PF02178] AT hook motif; [KOG0383] Predicted helicase 41.89 0.7907 58 Mapoly0021s0012 [PF00443] Ubiquitin carboxyl-terminal hydrolase; [GO:0006511] ubiquitin-dependent protein catabolic process; [PF02810] SEC-C motif; [KOG1865] Ubiquitin carboxyl-terminal hydrolase; [PTHR24006] FAMILY NOT NAMED; [PF01753] MYND finger 42.36 0.7635 59 Mapoly0143s0017 - 42.63 0.7633 60 Mapoly0014s0115 [PTHR15137] TRANSCRIPTION INITIATION FACTOR TFIID; [PF01433] Peptidase family M1; [GO:0008237] metallopeptidase activity; [GO:0008270] zinc ion binding; [K03128] transcription initiation factor TFIID subunit 2; [KOG1932] TATA binding protein associated factor 43.49 0.7737 61 Mapoly0010s0175 [GO:0003755] peptidyl-prolyl cis-trans isomerase activity; [PTHR11071] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF00160] Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; [K12735] peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8]; [GO:0008270] zinc ion binding; [GO:0000413] protein peptidyl-prolyl isomerization; [PF00098] Zinc knuckle; [GO:0006457] protein folding; [5.2.1.8] Peptidylprolyl isomerase.; [GO:0003676] nucleic acid binding; [KOG0415] Predicted peptidyl prolyl cis-trans isomerase; [PTHR11071:SF156] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 44.19 0.8063 62 Mapoly0010s0094 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [PF00454] Phosphatidylinositol 3- and 4-kinase; [KOG0889] Histone acetyltransferase SAGA, TRRAP/TRA1 component, PI-3 kinase superfamily; [PTHR11139:SF1] ATM-RELATED; [K08874] transformation/transcription domain-associated protein; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED 44.82 0.7950 63 Mapoly0024s0124 [GO:0005524] ATP binding; [GO:0003774] motor activity; [PTHR13140] MYOSIN; [GO:0005515] protein binding; [KOG0160] Myosin class V heavy chain; [PF00612] IQ calmodulin-binding motif; [PF00063] Myosin head (motor domain); [GO:0016459] myosin complex 44.99 0.7514 64 Mapoly0134s0010 [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PF12726] SEN1 N terminal; [PF13086] AAA domain; [KOG2812] Uncharacterized conserved protein; [PF13087] AAA domain 45.83 0.7649 65 Mapoly0002s0195 [PTHR15180] GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1; [PF04182] B-block binding subunit of TFIIIC 45.89 0.7973 66 Mapoly0122s0032 [PF14695] Lines C-terminus 47.37 0.6982 67 Mapoly0119s0035 - 48.22 0.7513 68 Mapoly0126s0027 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0390] DNA repair protein, SNF2 family; [PF00271] Helicase conserved C-terminal domain 48.48 0.7512 69 Mapoly0058s0092 - 48.57 0.6366 70 Mapoly0006s0033 [PF02373] JmjC domain, hydroxylase; [PTHR12549] JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN; [PF08879] WRC 49.86 0.7404 71 Mapoly0001s0391 [GO:0005634] nucleus; [PF05965] F/Y rich C-terminus 50.96 0.7863 72 Mapoly0006s0237 [PF13465] Zinc-finger double domain; [PF02373] JmjC domain, hydroxylase; [PF02375] jmjN domain; [PTHR10694] JUMONJI DOMAIN CONTAINING PROTEIN 51.38 0.7800 73 Mapoly0119s0048 [PTHR21654] FAMILY NOT NAMED; [PTHR21654:SF0] SUBFAMILY NOT NAMED; [PF13837] Myb/SANT-like DNA-binding domain 52.25 0.7703 74 Mapoly0013s0109 [PF00514] Armadillo/beta-catenin-like repeat; [PF00651] BTB/POZ domain; [GO:0005515] protein binding; [KOG0166] Karyopherin (importin) alpha; [PTHR23315] BETA CATENIN-RELATED ARMADILLO REPEAT-CONTAINING 52.33 0.7652 75 Mapoly0014s0041 [PTHR21650:SF4] GB DEF: HYPOTHETICAL PROTEIN AT1G61000/T7P1_14; [PTHR21650] MEMBRALIN/KINETOCHORE PROTEIN NUF2; [KOG2092] Uncharacterized conserved protein; [PF09746] Tumour-associated protein 52.54 0.6758 76 Mapoly0043s0067 [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [KOG0334] RNA helicase; [K12811] ATP-dependent RNA helicase DDX46/PRP5 [EC:3.6.4.13]; [PTHR24031:SF25] SUBFAMILY NOT NAMED 53.92 0.7792 77 Mapoly0072s0016 [GO:0005515] protein binding; [PTHR15398] BROMODOMAIN-CONTAINING PROTEIN 8; [PF00439] Bromodomain; [K11321] bromodomain-containing protein 8; [PTHR15398:SF0] SUBFAMILY NOT NAMED 53.94 0.7493 78 Mapoly0028s0116 [PTHR22884] SET DOMAIN PROTEINS 55.10 0.7910 79 Mapoly0004s0120 [PF04998] RNA polymerase Rpb1, domain 5; [GO:0003677] DNA binding; [PF00623] RNA polymerase Rpb1, domain 2; [PTHR19376] DNA-DIRECTED RNA POLYMERASE; [PF05000] RNA polymerase Rpb1, domain 4; [PF11523] Protein of unknown function (DUF3223); [PF04997] RNA polymerase Rpb1, domain 1; [GO:0006351] transcription, DNA-dependent; [GO:0003899] DNA-directed RNA polymerase activity; [PF04983] RNA polymerase Rpb1, domain 3; [KOG0261] RNA polymerase III, large subunit; [PTHR19376:SF33] DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'' 56.03 0.7654 80 Mapoly0068s0104 [PF04802] Component of IIS longevity pathway SMK-1; [KOG2175] Protein predicted to be involved in carbohydrate metabolism; [PTHR23318] ATP SYNTHASE GAMMA-RELATED 56.16 0.8000 81 Mapoly0001s0208 [PTHR31431] FAMILY NOT NAMED; [KOG4833] Uncharacterized conserved protein; [K14311] nuclear pore complex protein Nup188; [PF10487] Nucleoporin subcomplex protein binding to Pom34 56.92 0.7772 82 Mapoly0107s0024 [GO:0005524] ATP binding; [GO:0046982] protein heterodimerization activity; [KOG0018] Structural maintenance of chromosome protein 1 (sister chromatid cohesion complex Cohesin, subunit SMC1); [GO:0005515] protein binding; [GO:0003682] chromatin binding; [PTHR18937:SF12] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC1; [GO:0007064] mitotic sister chromatid cohesion; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0008278] cohesin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain; [K06636] structural maintenance of chromosome 1 57.24 0.7721 83 Mapoly0001s0127 [KOG1493] Anaphase-promoting complex (APC), subunit 11; [PF13923] Zinc finger, C3HC4 type (RING finger); [PTHR15242] SPLICING FACTOR, ARGININE/SERINE-RICH 2,RNAP C-TERM INTERACTING PROTEIN; [PF00628] PHD-finger; [GO:0005515] protein binding 57.33 0.7047 84 Mapoly0076s0056 [3.1.13.4] Poly(A)-specific ribonuclease.; [GO:0005634] nucleus; [PF04857] CAF1 family ribonuclease; [PTHR15092] POLY(A)-SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1; [K01148] poly(A)-specific ribonuclease [EC:3.1.13.4] 57.97 0.6731 85 Mapoly0075s0051 [GO:0006355] regulation of transcription, DNA-dependent; [PF02309] AUX/IAA family; [GO:0005634] nucleus; [PTHR31384] FAMILY NOT NAMED 58.69 0.7916 86 Mapoly0004s0112 - 59.40 0.7482 87 Mapoly0004s0056 [PTHR23424] SERUM AMYLOID A 59.63 0.7316 88 Mapoly0001s0473 - 61.19 0.7820 89 Mapoly0004s0038 [PF10440] Ubiquitin-binding WIYLD domain; [KOG1082] Histone H3 (Lys9) methyltransferase SUV39H1/Clr4, required for transcriptional silencing; [PF05033] Pre-SET motif; [GO:0005515] protein binding; [PF00856] SET domain; [GO:0008270] zinc ion binding; [PTHR22884:SF23] SET DOMAIN PROTEIN; [GO:0018024] histone-lysine N-methyltransferase activity; [PTHR22884] SET DOMAIN PROTEINS; [GO:0005634] nucleus; [GO:0034968] histone lysine methylation 62.33 0.6990 90 Mapoly0029s0052 [GO:0006357] regulation of transcription from RNA polymerase II promoter; [PTHR12950] FAMILY NOT NAMED; [GO:0001104] RNA polymerase II transcription cofactor activity; [GO:0016592] mediator complex; [PF06333] Mediator complex subunit 13 C-terminal 63.26 0.7779 91 Mapoly0004s0006 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [KOG0600] Cdc2-related protein kinase; [PTHR24056] CELL DIVISION PROTEIN KINASE 64.81 0.7437 92 Mapoly0053s0062 [PF12739] ER-Golgi trafficking TRAPP I complex 85 kDa subunit; [PTHR12975] TRANSPORT PROTEIN (TRAPP); [PTHR12975:SF6] SUBFAMILY NOT NAMED; [KOG1938] Protein with predicted involvement in meiosis (GSG1) 65.25 0.7482 93 Mapoly0079s0050 [2.7.11.25] Mitogen-activated protein kinase kinase kinase.; [PF07714] Protein tyrosine kinase; [K04424] sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]; [KOG0192] Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs; [PTHR23257] SERINE-THREONINE PROTEIN KINASE; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PF14381] Ethylene-responsive protein kinase Le-CTR1 65.42 0.7424 94 Mapoly0021s0043 - 65.81 0.7668 95 Mapoly0125s0020 [PF06972] Protein of unknown function (DUF1296); [PTHR12758] APOPTOSIS INHIBITOR 5-RELATED; [PTHR12758:SF13] APOPTOSIS INHIBITOR 5-RELATED 66.17 0.7175 96 Mapoly0080s0034 [2.1.1.43] Histone-lysine N-methyltransferase.; [KOG1082] Histone H3 (Lys9) methyltransferase SUV39H1/Clr4, required for transcriptional silencing; [K11419] histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43]; [PF05033] Pre-SET motif; [GO:0005515] protein binding; [PF00856] SET domain; [GO:0008270] zinc ion binding; [GO:0018024] histone-lysine N-methyltransferase activity; [PTHR22884] SET DOMAIN PROTEINS; [GO:0005634] nucleus; [GO:0034968] histone lysine methylation; [PF13771] PHD-like zinc-binding domain 66.75 0.7605 97 Mapoly0084s0045 [PF07719] Tetratricopeptide repeat; [KOG1211] Amidases; [PF13414] TPR repeat; [PTHR11895] AMIDASE; [GO:0016884] carbon-nitrogen ligase activity, with glutamine as amido-N-donor; [PTHR11895:SF6] AMIDASE; [PF01425] Amidase 66.75 0.7285 98 Mapoly0061s0115 [PTHR23079] RNA-DEPENDENT RNA POLYMERASE; [GO:0003968] RNA-directed RNA polymerase activity; [PTHR23079:SF1] RNA-DEPENDENT RNA POLYMERASE; [KOG0988] RNA-directed RNA polymerase QDE-1 required for posttranscriptional gene silencing and RNA interference; [PF05183] RNA dependent RNA polymerase 69.39 0.6425 99 Mapoly0043s0131 [PF06465] Domain of Unknown Function (DUF1087) 71.24 0.7042 100 Mapoly0042s0123 [K12875] apoptotic chromatin condensation inducer in the nucleus; [GO:0003676] nucleic acid binding; [PTHR14127] APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; [PF02037] SAP domain 73.48 0.7802 101 Mapoly0039s0001 - 73.54 0.7454 102 Mapoly0032s0018 [KOG0796] Spliceosome subunit 74.57 0.7687 103 Mapoly0091s0014 [PTHR12596:SF1] GB DEF: T27C4.14 PROTEIN; [PTHR12596] EXPORTIN 4,7-RELATED; [KOG4541] Nuclear transport receptor exportin 4 (importin beta superfamily) 74.88 0.7531 104 Mapoly0013s0201 [PTHR23269:SF0] SUBFAMILY NOT NAMED; [KOG0128] RNA-binding protein SART3 (RRM superfamily); [PF05391] Lsm interaction motif; [GO:0003676] nucleic acid binding; [PTHR23269] RIBONUCLEOPROTEIN-RELATED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 75.99 0.7648 105 Mapoly0024s0008 [GO:0003677] DNA binding; [KOG1793] Uncharacterized conserved protein; [PF08711] TFIIS helical bundle-like domain; [GO:0005634] nucleus; [GO:0006351] transcription, DNA-dependent; [PTHR22908] MIDASIN-RELATED 76.35 0.6635 106 Mapoly0024s0108 [PF13371] Tetratricopeptide repeat; [PTHR23082] TRANSCRIPTION INITIATION FACTOR IIIC (TFIIIC), POLYPEPTIDE 3-RELATED; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13174] Tetratricopeptide repeat; [KOG2076] RNA polymerase III transcription factor TFIIIC 77.46 0.7194 107 Mapoly0021s0042 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [KOG0298] DEAD box-containing helicase-like transcription factor/DNA repair protein; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [PF00271] Helicase conserved C-terminal domain 77.77 0.7507 108 Mapoly0021s0077 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [KOG0796] Spliceosome subunit; [GO:0003729] mRNA binding 78.04 0.7555 109 Mapoly0084s0051 [2.1.1.43] Histone-lysine N-methyltransferase.; [GO:0005515] protein binding; [PF00856] SET domain; [KOG1079] Transcriptional repressor EZH1; [PTHR22884] SET DOMAIN PROTEINS; [K11430] enhancer of zeste [EC:2.1.1.43] 78.69 0.7304 110 Mapoly0006s0222 [GO:0005524] ATP binding; [GO:0032300] mismatch repair complex; [KOG1977] DNA mismatch repair protein - MLH3 family; [PTHR10073:SF7] DNA MISMATCH REPAIR PROTEIN MLH3; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [GO:0007131] reciprocal meiotic recombination; [PTHR10073] DNA MISMATCH REPAIR PROTEIN (MLH, PMS, MUTL); [GO:0006298] mismatch repair; [PF08676] MutL C terminal dimerisation domain; [GO:0030983] mismatched DNA binding; [PF01119] DNA mismatch repair protein, C-terminal domain; [K08739] DNA mismatch repair protein MLH3 79.75 0.7366 111 Mapoly0045s0119 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR13161] SPLICING FACTOR (SUPPRESSOR OF WHITE APRICOT); [PF01805] Surp module; [PF09750] Alternative splicing regulator; [KOG1847] mRNA splicing factor 81.61 0.7410 112 Mapoly0067s0068 [KOG2266] Chromatin-associated protein Dek and related proteins, contains SAP DNA binding domain; [PTHR13468:SF1] DEK ONCOGENE; [PF08766] DEK C terminal domain; [PTHR13468] DEK PROTEIN 81.83 0.7660 113 Mapoly0006s0120 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PF00139] Legume lectin domain; [GO:0030246] carbohydrate binding; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 82.46 0.7071 114 Mapoly0003s0033 [GO:0003723] RNA binding; [2.7.7.19] Polynucleotide adenylyltransferase.; [GO:0043631] RNA polyadenylation; [PF04928] Poly(A) polymerase central domain; [GO:0004652] polynucleotide adenylyltransferase activity; [GO:0005634] nucleus; [PTHR10682] POLY(A) POLYMERASE; [PF04926] Poly(A) polymerase predicted RNA binding domain; [PF01909] Nucleotidyltransferase domain; [GO:0016779] nucleotidyltransferase activity; [KOG2245] Poly(A) polymerase and related nucleotidyltransferases; [K14376] poly(A) polymerase [EC:2.7.7.19] 83.14 0.6798 115 Mapoly0032s0104 [GO:0008601] protein phosphatase type 2A regulator activity; [K04354] protein phosphatase 2 (formerly 2A), regulatory subunit B; [KOG1354] Serine/threonine protein phosphatase 2A, regulatory subunit; [GO:0000159] protein phosphatase type 2A complex; [GO:0007165] signal transduction; [PTHR11871] PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B; [PTHR11871:SF0] PROTEIN PHOSPHATASE PP2A 55 KDA REGULATORY SUBUNIT 83.25 0.6390 116 Mapoly0135s0035 [GO:0003676] nucleic acid binding; [PF02037] SAP domain 83.50 0.7576 117 Mapoly0049s0040 [GO:0005524] ATP binding; [PTHR24058:SF23] DUAL-SPECIFICITY TYROSINE REGULATED PROTEIN KINASE 2; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24058] DUAL SPECIFICITY PROTEIN KINASE; [KOG0667] Dual-specificity tyrosine-phosphorylation regulated kinase; [GO:0006468] protein phosphorylation 83.98 0.7585 118 Mapoly0014s0197 [KOG4822] Predicted nuclear membrane protein involved in mRNA transport and sex determination via splicing modulation; [PTHR23185:SF0] SUBFAMILY NOT NAMED; [PTHR23185] UNCHARACTERIZED 84.07 0.7649 119 Mapoly0218s0012 [PTHR15744:SF0] SUBFAMILY NOT NAMED; [PTHR15744] BLOM7 86.59 0.7373 120 Mapoly0005s0111 [PF13414] TPR repeat; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR 87.50 0.7296 121 Mapoly0029s0003 [KOG1824] TATA-binding protein-interacting protein; [PTHR12696] TIP120; [PF08623] TATA-binding protein interacting (TIP20); [PF13646] HEAT repeats 87.95 0.7522 122 Mapoly0013s0006 [GO:0008270] zinc ion binding; [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PTHR23336] ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3.; [PF07496] CW-type Zinc Finger 88.68 0.7359 123 Mapoly0014s0121 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0390] DNA repair protein, SNF2 family; [PF00271] Helicase conserved C-terminal domain 89.10 0.7321 124 Mapoly0067s0005 [PTHR24012] FAMILY NOT NAMED; [PTHR24012:SF39] SUBFAMILY NOT NAMED; [KOG0147] Transcriptional coactivator CAPER (RRM superfamily); [GO:0003676] nucleic acid binding; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [K13091] RNA-binding protein 39; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 90.39 0.7559 125 Mapoly0082s0054 [PF10358] N-terminal C2 in EEIG1 and EHBP1 proteins; [PTHR31593] FAMILY NOT NAMED; [PTHR31593:SF0] SUBFAMILY NOT NAMED 90.52 0.6731 126 Mapoly0039s0014 [PTHR23125] F-BOX/LEUCINE RICH REPEAT PROTEIN 91.19 0.6912 127 Mapoly0001s0149 [K11596] argonaute; [PF02170] PAZ domain; [PF08699] Domain of unknown function (DUF1785); [PTHR22891] EUKARYOTIC TRANSLATION INITIATION FACTOR 2C; [PF02171] Piwi domain; [GO:0005515] protein binding; [KOG1041] Translation initiation factor 2C (eIF-2C) and related proteins 91.42 0.7257 128 Mapoly0051s0078 [GO:0006355] regulation of transcription, DNA-dependent; [KOG0266] WD40 repeat-containing protein; [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [PF00400] WD domain, G-beta repeat 91.92 0.7303 129 Mapoly0046s0104 [PF00628] PHD-finger; [GO:0005515] protein binding 94.36 0.7425 130 Mapoly0140s0030 [PF00773] RNB domain; [PTHR23355] RIBONUCLEASE; [KOG2102] Exosomal 3'-5' exoribonuclease complex, subunit Rrp44/Dis3 94.37 0.7357 131 Mapoly0020s0107 [KOG4626] O-linked N-acetylglucosamine transferase OGT; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13432] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat; [PF13844] Glycosyl transferase family 41; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR 95.40 0.7351 132 Mapoly0098s0013 [KOG1634] Predicted transcription factor DATF1, contains PHD and TFS2M domains; [PF07500] Transcription factor S-II (TFIIS), central domain; [PTHR11477] TRANSCRIPTION ELONGATION FACTOR S-II; [GO:0006351] transcription, DNA-dependent; [PF07744] SPOC domain 95.53 0.7382 133 Mapoly0030s0101 [GO:0042393] histone binding; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [K11647] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-]; [KOG0386] Chromatin remodeling complex SWI/SNF, component SWI2 and related ATPases (DNA/RNA helicase superfamily); [PTHR10799:SF209] GLOBAL TRANSCRIPTION ACTIVATOR SNF2L2 (ATP-DEPENDENT HELICASE SMARCA2); [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [PF14619] Snf2-ATP coupling, chromatin remodelling complex 95.81 0.7562 134 Mapoly0047s0113 - 97.86 0.7167 135 Mapoly0022s0114 [PTHR12433] PROSTATE TUMOR OVEREXPRESSED GENE 1 (PTOV1); [PF11265] Mediator complex subunit 25 von Willebrand factor type A 98.82 0.6589 136 Mapoly0028s0103 [PF01713] Smr domain; [GO:0003677] DNA binding; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K07456] DNA mismatch repair protein MutS2; [GO:0016887] ATPase activity; [PTHR11361:SF14] DNA MISMATCH REPAIR PROTEIN MUTS2; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [GO:0045910] negative regulation of DNA recombination 99.00 0.6277 137 Mapoly0251s0001 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [KOG0663] Protein kinase PITSLRE and related kinases; [K08818] cell division cycle 2-like [EC:2.7.11.22]; [PTHR24056:SF107] CELL DIVISION PROTEIN KINASE 2 (CDC2-RELATED KINASE); [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 99.50 0.7526 138 Mapoly0043s0127 [GO:0031625] ubiquitin protein ligase binding; [GO:0031461] cullin-RING ubiquitin ligase complex; [GO:0006511] ubiquitin-dependent protein catabolic process; [K10609] cullin 4; [PF10557] Cullin protein neddylation domain; [PTHR11932] CULLIN; [PF00888] Cullin family; [KOG2167] Cullins; [PTHR11932:SF27] SUBFAMILY NOT NAMED 100.05 0.7164 139 Mapoly0001s0041 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF00271] Helicase conserved C-terminal domain; [GO:0005515] protein binding; [KOG0386] Chromatin remodeling complex SWI/SNF, component SWI2 and related ATPases (DNA/RNA helicase superfamily); [PF00439] Bromodomain; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain 101.14 0.7727 140 Mapoly0113s0018 - 101.34 0.7116 141 Mapoly0074s0043 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [GO:0003729] mRNA binding 101.49 0.7456 142 Mapoly0143s0016 - 101.65 0.6701 143 Mapoly0075s0058 [KOG4416] Uncharacterized conserved protein; [PF07986] Tubulin binding cofactor C; [PTHR16052] UNCHARACTERIZED 102.25 0.6890 144 Mapoly0007s0100 [PTHR15828] CYTOKINE RECEPTOR-LIKE FACTOR 3 102.47 0.7472 145 Mapoly0014s0196 [PTHR12272] FAMILY NOT NAMED; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [KOG3741] Poly(A) ribonuclease subunit; [K12572] PAB-dependent poly(A)-specific ribonuclease subunit 3; [GO:0046872] metal ion binding 104.30 0.7203 146 Mapoly0004s0169 [GO:0003677] DNA binding; [GO:0006338] chromatin remodeling; [GO:0005524] ATP binding; [PF09110] HAND; [K11654] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]; [GO:0043044] ATP-dependent chromatin remodeling; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [GO:0005634] nucleus; [PTHR10799:SF73] ISWI CHROMATIN-REMODELING COMPLEX ATPASE ISW1; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [KOG0385] Chromatin remodeling complex WSTF-ISWI, small subunit; [GO:0003676] nucleic acid binding; [GO:0031491] nucleosome binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [PF09111] SLIDE 104.46 0.7536 147 Mapoly0165s0024 [GO:0006338] chromatin remodeling; [GO:0043968] histone H2A acetylation; [PF00249] Myb-like DNA-binding domain; [K11324] DNA methyltransferase 1-associated protein 1; [GO:0043967] histone H4 acetylation; [KOG2656] DNA methyltransferase 1-associated protein-1; [GO:0003682] chromatin binding; [PTHR12855] FAMILY NOT NAMED; [GO:0035267] NuA4 histone acetyltransferase complex; [GO:0006281] DNA repair; [PTHR12855:SF10] SUBFAMILY NOT NAMED 105.32 0.7378 148 Mapoly0158s0003 [PF13921] Myb-like DNA-binding domain 105.33 0.6666 149 Mapoly0032s0010 - 105.92 0.7682 150 Mapoly0033s0024 [GO:0005524] ATP binding; [K14572] midasin; [PF07728] AAA domain (dynein-related subfamily); [GO:0016887] ATPase activity; [KOG1808] AAA ATPase containing von Willebrand factor type A (vWA) domain; [PTHR22908] MIDASIN-RELATED 107.06 0.7151 151 Mapoly0001s0542 [KOG0266] WD40 repeat-containing protein; [PTHR13743] BEIGE/BEACH-RELATED; [GO:0005515] protein binding; [PF02138] Beige/BEACH domain; [PF13385] Concanavalin A-like lectin/glucanases superfamily; [PF14844] PH domain associated with Beige/BEACH; [PF00400] WD domain, G-beta repeat 107.39 0.7347 152 Mapoly0001s0355 [GO:0016020] membrane; [GO:0004222] metalloendopeptidase activity; [PF01457] Leishmanolysin; [PF07974] EGF-like domain; [KOG2556] Leishmanolysin-like peptidase (Peptidase M8 family); [3.4.24.36] Leishmanolysin.; [GO:0007155] cell adhesion; [GO:0006508] proteolysis; [K01404] leishmanolysin [EC:3.4.24.36]; [PTHR10942] LEISHMANOLYSIN-LIKE PEPTIDASE 108.18 0.7248 153 Mapoly0001s0263 [PF08766] DEK C terminal domain; [GO:0005515] protein binding; [KOG1946] RNA polymerase I transcription factor UAF; [PF02201] SWIB/MDM2 domain; [PTHR13844] BRG-1 ASSOCIATED FACTOR 60 (BAF60) 108.68 0.6218 154 Mapoly0144s0028 [GO:0016020] membrane; [PTHR11384] ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER; [GO:0005524] ATP binding; [KOG0060] Long-chain acyl-CoA transporter, ABC superfamily (involved in peroxisome organization and biogenesis); [PF06472] ABC transporter transmembrane region 2; [GO:0016887] ATPase activity; [GO:0006810] transport; [PF00005] ABC transporter 109.15 0.7110 155 Mapoly0005s0201 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005515] protein binding; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PTHR12348] TSC22; [PF00498] FHA domain 109.98 0.7229 156 Mapoly4108s0001 [PTHR23140] RNA PROCESSING PROTEIN LD23810P 109.98 0.6979 157 Mapoly0001s0430 [PTHR21402] UNCHARACTERIZED; [PF05253] U11-48K-like CHHC zinc finger 110.52 0.6934 158 Mapoly0035s0128 [PF03031] NLI interacting factor-like phosphatase; [GO:0005515] protein binding; [PTHR12210] NUCLEAR LIM INTERACTOR-INTERACTING FACTOR-RELATED 110.90 0.5609 159 Mapoly0177s0011 [GO:0006289] nucleotide-excision repair; [PF00867] XPG I-region; [PF00752] XPG N-terminal domain; [GO:0003697] single-stranded DNA binding; [K10846] DNA excision repair protein ERCC-5; [GO:0005634] nucleus; [PTHR11081:SF1] DNA-REPAIR PROTEIN XP-G; [GO:0006281] DNA repair; [GO:0004518] nuclease activity; [PTHR11081] XP-G/RAD2 DNA REPAIR ENDONUCLEASE FAMILY; [GO:0004519] endonuclease activity 111.00 0.7113 160 Mapoly0001s0516 [KOG2428] Uncharacterized conserved protein; [PF04004] Leo1-like protein; [PTHR23146] LEO1 PROTEIN; [PTHR23146:SF0] SUBFAMILY NOT NAMED 111.31 0.6844 161 Mapoly0042s0059 [PTHR16426] UBINUCLEIN/YEMANUCLEIN; [PF08729] HPC2 and ubinuclein domain 112.49 0.7400 162 Mapoly0144s0001 [PF08312] cwf21 domain; [PTHR23140:SF0] SUBFAMILY NOT NAMED; [PTHR23140] RNA PROCESSING PROTEIN LD23810P 112.92 0.6466 163 Mapoly0007s0143 [KOG2235] Uncharacterized conserved protein; [PTHR31057] FAMILY NOT NAMED; [PF09743] Uncharacterized conserved protein (DUF2042); [PTHR31057:SF0] SUBFAMILY NOT NAMED 113.07 0.6982 164 Mapoly0042s0035 [PF01433] Peptidase family M1; [GO:0008237] metallopeptidase activity; [3.4.11.2] Membrane alanyl aminopeptidase.; [GO:0008270] zinc ion binding; [PTHR11533] PROTEASE M1 ZINC METALLOPROTEASE; [KOG1046] Puromycin-sensitive aminopeptidase and related aminopeptidases; [K01256] aminopeptidase N [EC:3.4.11.2]; [GO:0006508] proteolysis; [PF11940] Domain of unknown function (DUF3458) 117.45 0.6730 165 Mapoly0063s0002 [PF01480] PWI domain; [K13171] serine/arginine repetitive matrix protein 1; [PTHR23148] SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN; [GO:0006397] mRNA processing; [KOG2146] Splicing coactivator SRm160/300, subunit SRm160 (contains PWI domain) 118.06 0.7253 166 Mapoly0037s0093 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG4280] Kinesin-like protein; [PTHR24115:SF87] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [PF12711] Kinesin motor; [GO:0003777] microtubule motor activity 118.66 0.7310 167 Mapoly0105s0035 [PTHR12341] 5'-3' EXORIBONUCLEASE; [PF03159] XRN 5'-3' exonuclease N-terminus; [K12619] 5'-3' exoribonuclease 2 [EC:3.1.13.-]; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [3.1.13.-] Exoribonucleases producing 5'-phosphomonoesters.; [GO:0003676] nucleic acid binding; [GO:0004527] exonuclease activity 118.66 0.7419 168 Mapoly0038s0101 [K12837] splicing factor U2AF 65 kDa subunit; [PTHR23139] RNA-BINDING PROTEIN; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG0120] Splicing factor U2AF, large subunit (RRM superfamily); [GO:0003676] nucleic acid binding; [PTHR23139:SF9] SPLICING FACTOR U2AF LARGE SUBUNIT; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 120.42 0.7388 169 Mapoly0001s0472 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED 120.95 0.7510 170 Mapoly0159s0020 [K05544] tRNA-dihydrouridine synthase 3 [EC:1.-.-.-]; [GO:0050660] flavin adenine dinucleotide binding; [GO:0055114] oxidation-reduction process; [PTHR11082:SF8] TRNA-DIHYDROURIDINE SYNTHASE 3; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PF01207] Dihydrouridine synthase (Dus); [KOG2333] Uncharacterized conserved protein; [GO:0008033] tRNA processing; [PTHR11082] TRNA-DIHYDROURIDINE SYNTHASE; [GO:0046872] metal ion binding; [GO:0017150] tRNA dihydrouridine synthase activity; [1.-.-.-] Oxidoreductases. 121.60 0.7116 171 Mapoly0043s0012 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [K13123] G patch domain-containing protein 1; [PTHR13384] FAMILY NOT NAMED; [KOG2138] Predicted RNA binding protein, contains G-patch domain; [PF07713] Protein of unknown function (DUF1604); [PF01805] Surp module 123.09 0.7460 172 Mapoly0074s0075 [PTHR31546] FAMILY NOT NAMED; [PF10033] Autophagy-related protein 13; [KOG4573] Phosphoprotein involved in cytoplasm to vacuole targeting and autophagy 123.90 0.6904 173 Mapoly0012s0166 [PF09405] CASC3/Barentsz eIF4AIII binding; [PTHR22814:SF47] HEAVY-METAL-ASSOCIATED DOMAIN-CONTAINING PROTEIN; [PTHR22814] COPPER TRANSPORT PROTEIN ATOX1-RELATED 124.71 0.7096 174 Mapoly0012s0200 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [KOG0796] Spliceosome subunit; [GO:0003729] mRNA binding 125.29 0.7078 175 Mapoly0091s0060 - 126.15 0.6818 176 Mapoly0104s0042 [PTHR22846:SF2] TRANSDUCIN BETA-LIKE 1; [GO:0005515] protein binding; [PTHR22846] WD40 REPEAT PROTEIN; [KOG0273] Beta-transducin family (WD-40 repeat) protein; [PF08513] LisH; [PF00400] WD domain, G-beta repeat 126.42 0.7301 177 Mapoly0069s0028 [3.1.27.-] Endoribonucleases producing other than 5'-phosphomonoesters.; [PF07521] RNA-metabolising metallo-beta-lactamase; [PTHR11203] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF11718] Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term; [KOG1137] mRNA cleavage and polyadenylation factor II complex, BRR5 (CPSF subunit); [PF00753] Metallo-beta-lactamase superfamily; [K14403] cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]; [PF10996] Beta-Casp domain; [PTHR11203:SF32] UNCHARACTERIZED 127.22 0.6714 178 Mapoly0037s0026 [PTHR15598] AUTOANTIGEN RCD8; [GO:0005515] protein binding; [KOG1916] Nuclear protein, contains WD40 repeats; [K12616] enhancer of mRNA-decapping protein 4; [PF00400] WD domain, G-beta repeat 127.23 0.6765 179 Mapoly0038s0063 [GO:0030904] retromer complex; [GO:0015031] protein transport; [PF03635] Vacuolar protein sorting-associated protein 35; [GO:0042147] retrograde transport, endosome to Golgi; [PTHR13673:SF0] SUBFAMILY NOT NAMED; [PTHR13673] ESOPHAGEAL CANCER ASSOCIATED PROTEIN; [KOG3682] Predicted membrane protein (associated with esophageal cancer in humans) 128.12 0.7059 180 Mapoly0111s0041 - 128.12 0.4794 181 Mapoly0052s0086 [PF05641] Agenet domain; [PTHR31917] FAMILY NOT NAMED 130.05 0.7405 182 Mapoly0104s0038 [PF14648] FAM91 C-terminus; [PF14647] FAM91 N-terminus; [KOG3707] Uncharacterized conserved protein 132.48 0.5541 183 Mapoly0005s0093 [KOG1883] Cofactor required for Sp1 transcriptional activation, subunit 3; [PF11573] Mediator complex subunit 23; [PTHR12691] FAMILY NOT NAMED 133.70 0.7034 184 Mapoly0045s0077 [PTHR11807:SF2] CELL CYCLE PROTEIN MESJ; [GO:0005524] ATP binding; [GO:0005737] cytoplasm; [GO:0000166] nucleotide binding; [PTHR11807] ATPASES OF THE PP SUPERFAMILY-RELATED; [GO:0016879] ligase activity, forming carbon-nitrogen bonds; [PF01171] PP-loop family; [GO:0008033] tRNA processing 135.37 0.6735 185 Mapoly0012s0196 - 135.58 0.5613 186 Mapoly0140s0044 [GO:0005524] ATP binding; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [PTHR24361:SF148] SERINE/THREONINE PROTEIN KINASE; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24361] MITOGEN-ACTIVATED KINASE KINASE KINASE 136.97 0.7285 187 Mapoly0063s0041 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR23340] ARGININE/SERINE RICH SPLICING FACTOR SF4/14; [PF01585] G-patch domain; [GO:0003676] nucleic acid binding; [PF01805] Surp module 137.93 0.7089 188 Mapoly0001s0490 [PTHR21512:SF5] GB DEF: HYPOTHETICAL PROTEIN T5K6_30; [PTHR21512] FAMILY NOT NAMED; [KOG1953] Targeting complex (TRAPP) subunit; [PF08626] Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit 138.14 0.6901 189 Mapoly0007s0002 [PTHR22774] UNCHARACTERIZED; [PF12624] N-terminal region of Chorein, a TM vesicle-mediated sorter; [PTHR22774:SF11] UHRF1-BINDING PROTEIN 1 UBIQUITIN-LIKE CONTAINING PHD AND RING FINGER DOMAINS 1 138.74 0.6597 190 Mapoly0001s0493 [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [K12858] ATP-dependent RNA helicase DDX23/PRP28 [EC:3.6.4.13]; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [KOG0333] U5 snRNP-like RNA helicase subunit; [PTHR24031:SF23] SUBFAMILY NOT NAMED 139.75 0.7160 191 Mapoly0132s0046 [PF00855] PWWP domain; [PTHR12550] HEPATOMA-DERIVED GROWTH FACTOR-RELATED; [PTHR12550:SF5] UNCHARACTERIZED 139.93 0.7012 192 Mapoly0104s0010 [PTHR17204:SF5] PRE-MRNA PROCESSING PROTEIN PRP39-RELATED; [K13217] pre-mRNA-processing factor 39; [KOG1258] mRNA processing protein; [GO:0006397] mRNA processing; [GO:0005634] nucleus; [PF05843] Suppressor of forked protein (Suf); [PTHR17204] PRE-MRNA PROCESSING PROTEIN PRP39-RELATED 140.71 0.7089 193 Mapoly0030s0061 [GO:0005663] DNA replication factor C complex; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [GO:0003689] DNA clamp loader activity; [PF00533] BRCA1 C Terminus (BRCT) domain; [K10754] replication factor C subunit 1; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08519] Replication factor RFC1 C terminal domain; [KOG1968] Replication factor C, subunit RFC1 (large subunit) 141.59 0.7093 194 Mapoly0039s0120 [KOG1805] DNA replication helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PTHR10887:SF14] DNA2-LIKE HELICASE; [3.6.4.12] DNA helicase.; [PF13086] AAA domain; [GO:0033567] DNA replication, Okazaki fragment processing; [PF01930] Domain of unknown function DUF83; [GO:0017108] 5'-flap endonuclease activity; [GO:0043142] single-stranded DNA-dependent ATPase activity; [PF13087] AAA domain; [PF08696] DNA replication factor Dna2; [K10742] DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12] 141.65 0.7039 195 Mapoly0015s0190 - 143.03 0.6968 196 Mapoly0038s0009 [K11279] nucleosome assembly protein 1-like 1; [PF00956] Nucleosome assembly protein (NAP); [PTHR11875:SF7] NUCLEOSOME ASSEMBLY PROTEIN; [GO:0005634] nucleus; [GO:0006334] nucleosome assembly; [PTHR11875] TESTIS-SPECIFIC Y-ENCODED PROTEIN; [KOG1507] Nucleosome assembly protein NAP-1 143.29 0.6333 197 Mapoly0027s0185 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF39] CDC2-RELATED PROTEIN KINASE; [KOG0600] Cdc2-related protein kinase; [K08819] Cdc2-related kinase, arginine/serine-rich [EC:2.7.11.22]; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 145.20 0.7082 198 Mapoly0011s0132 - 145.30 0.7017 199 Mapoly0061s0046 [KOG0170] E3 ubiquitin protein ligase; [PTHR11254:SF73] HECT UBIQUITIN-PROTEIN LIGASE 3 (KAKTUS PROTEIN); [PTHR11254] HECT DOMAIN UBIQUITIN-PROTEIN LIGASE; [6.3.2.19] Ubiquitin--protein ligase.; [GO:0004842] ubiquitin-protein ligase activity; [K10590] E3 ubiquitin-protein ligase TRIP12 [EC:6.3.2.19]; [PF00632] HECT-domain (ubiquitin-transferase) 145.34 0.7345 200 Mapoly0069s0061 [GO:0004677] DNA-dependent protein kinase activity; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [K06642] DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]; [PF08163] NUC194 domain; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0005634] nucleus; [PF00454] Phosphatidylinositol 3- and 4-kinase; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [GO:0006303] double-strand break repair via nonhomologous end joining 145.60 0.6834