Guide Gene

Gene ID
Mapoly0023s0117
Organism
Marchantia polymorpha
Platform ID
Mpo
Description
[PTHR10139] DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11A; [PF04152] Mre11 DNA-binding presumed domain; [KOG2310] DNA repair exonuclease MRE11; [GO:0006259] DNA metabolic process; [PF00149] Calcineurin-like phosphoesterase; [GO:0006302] double-strand break repair; [GO:0016787] hydrolase activity; [GO:0030145] manganese ion binding; [GO:0005634] nucleus; [GO:0004527] exonuclease activity; [K10865] double-strand break repair protein MRE11; [GO:0004519] endonuclease activity

Coexpressed Gene List


Marchantia polymorpha
Rank Gene ID Description MR PCC
Guide Mapoly0023s0117 [PTHR10139] DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11A; [PF04152] Mre11 DNA-binding presumed domain; [KOG2310] DNA repair exonuclease MRE11; [GO:0006259] DNA metabolic process; [PF00149] Calcineurin-like phosphoesterase; [GO:0006302] double-strand break repair; [GO:0016787] hydrolase activity; [GO:0030145] manganese ion binding; [GO:0005634] nucleus; [GO:0004527] exonuclease activity; [K10865] double-strand break repair protein MRE11; [GO:0004519] endonuclease activity 0.00 1.0000
1 Mapoly0155s0001 [GO:0016597] amino acid binding; [PF01842] ACT domain; [GO:0008152] metabolic process; [PTHR31096] FAMILY NOT NAMED 1.41 0.8419
2 Mapoly0065s0033 [GO:0003723] RNA binding; [3.1.26.5] Ribonuclease P.; [K03538] ribonuclease P protein subunit POP4 [EC:3.1.26.5]; [GO:0000172] ribonuclease MRP complex; [PF01868] Domain of unknown function UPF0086; [PTHR13348] RIBONUCLEASE P; [GO:0006364] rRNA processing; [GO:0008033] tRNA processing; [GO:0030677] ribonuclease P complex; [GO:0006379] mRNA cleavage; [KOG4046] RNase MRP and P, subunit POP4/p29; [GO:0004540] ribonuclease activity 4.24 0.8098
3 Mapoly0014s0096 [GO:0005524] ATP binding; [K10755] replication factor C subunit 2/4; [KOG0989] Replication factor C, subunit RFC4; [PTHR11669] REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08542] Replication factor C C-terminal domain 5.48 0.8196
4 Mapoly0105s0060 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [K12898] heterogeneous nuclear ribonucleoprotein F/H; [KOG4211] Splicing factor hnRNP-F and related RNA-binding proteins; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED 6.16 0.8351
5 Mapoly0006s0052 [GO:0003723] RNA binding; [GO:0004523] ribonuclease H activity; [PF01351] Ribonuclease HII; [PTHR10954] RIBONUCLEASE H2 SUBUNIT A; [K10743] ribonuclease H2 subunit A [EC:3.1.26.4]; [3.1.26.4] Ribonuclease H.; [PTHR10954:SF7] RIBONUCLEASE H2 SUBUNIT A; [KOG2299] Ribonuclease HI 7.21 0.7997
6 Mapoly0068s0031 [KOG1882] Transcriptional regulator SNIP1, contains FHA domain; [GO:0005515] protein binding; [K13108] smad nuclear-interacting protein 1; [PF00498] FHA domain; [PTHR23308] NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 7.48 0.8098
7 Mapoly0005s0061 [PF00089] Trypsin; [PTHR22939] SERINE PROTEASE FAMILY S1C HTRA-RELATED; [GO:0005515] protein binding; [PF13180] PDZ domain; [KOG1320] Serine protease; [GO:0004252] serine-type endopeptidase activity; [GO:0006508] proteolysis 8.77 0.8012
8 Mapoly0007s0066 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PTHR19306:SF1] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5 SMC5; [KOG0979] Structural maintenance of chromosome protein SMC5/Spr18, SMC superfamily; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0000724] double-strand break repair via homologous recombination 8.94 0.8218
9 Mapoly0019s0059 [PTHR31398:SF0] SUBFAMILY NOT NAMED; [PTHR31398] FAMILY NOT NAMED; [PF03962] Mnd1 family; [KOG3433] Protein involved in meiotic recombination/predicted coiled-coil protein 9.38 0.8239
10 Mapoly0052s0123 [PTHR12616] VACUOLAR PROTEIN SORTING VPS41 12.00 0.7882
11 Mapoly0066s0041 [GO:0030915] Smc5-Smc6 complex; [PTHR21330] UNCHARACTERIZED; [GO:0019789] SUMO ligase activity; [PF11789] Zinc-finger of the MIZ type in Nse subunit; [GO:0000724] double-strand break repair via homologous recombination 12.00 0.7933
12 Mapoly0187s0003 [PTHR22880] FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; [K06062] histone acetyltransferase [EC:2.3.1.48]; [GO:0005515] protein binding; [PF00439] Bromodomain; [GO:0008080] N-acetyltransferase activity; [PF00583] Acetyltransferase (GNAT) family; [2.3.1.48] Histone acetyltransferase. 12.12 0.7839
13 Mapoly0122s0062 [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 12.37 0.8272
14 Mapoly0158s0032 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [K10728] topoisomerase (DNA) II binding protein 1; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 15.30 0.7783
15 Mapoly0139s0008 [PF14929] TAF RNA Polymerase I subunit A 15.59 0.7777
16 Mapoly0063s0059 [GO:0000812] Swr1 complex; [GO:0006338] chromatin remodeling; [GO:0006355] regulation of transcription, DNA-dependent; [GO:0031011] Ino80 complex; [PTHR11937:SF47] SUBFAMILY NOT NAMED; [GO:0035267] NuA4 histone acetyltransferase complex; [PF00022] Actin; [GO:0006281] DNA repair; [PTHR11937] ACTIN; [KOG0679] Actin-related protein - Arp4p/Act3p 16.25 0.7831
17 Mapoly0050s0101 [3.4.21.48] Cerevisin.; [K01336] cerevisin [EC:3.4.21.48]; [GO:0004252] serine-type endopeptidase activity; [PF00082] Subtilase family; [PF00090] Thrombospondin type 1 domain; [PF00053] Laminin EGF-like (Domains III and V); [GO:0006508] proteolysis; [PTHR10795] PROPROTEIN CONVERTASE SUBTILISIN/KEXIN 16.31 0.7685
18 Mapoly0052s0092 [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding; [KOG0106] Alternative splicing factor SRp55/B52/SRp75 (RRM superfamily); [PTHR10548] SPLICING FACTOR, ARGININE/SERINE-RICH; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 17.97 0.7887
19 Mapoly0009s0012 [KOG0113] U1 small nuclear ribonucleoprotein (RRM superfamily); [PTHR13952] U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD; [GO:0003676] nucleic acid binding; [K13155] U11/U12 small nuclear ribonucleoprotein 35 kDa protein; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 18.22 0.7373
20 Mapoly0133s0013 [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10615] HISTONE ACETYLTRANSFERASE; [PF00856] SET domain 18.33 0.8148
21 Mapoly0013s0011 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 18.97 0.8003
22 Mapoly0107s0034 [3.5.1.98] Histone deacetylase.; [KOG1342] Histone deacetylase complex, catalytic component RPD3; [K06067] histone deacetylase 1/2 [EC:3.5.1.98]; [PF00850] Histone deacetylase domain; [PTHR10625] HISTONE DEACETYLASE 18.97 0.7848
23 Mapoly0226s0007 [PF00817] impB/mucB/samB family; [2.7.7.7] DNA-directed DNA polymerase.; [GO:0006281] DNA repair; [PF11799] impB/mucB/samB family C-terminal domain; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [PTHR11076:SF11] DNA POLYMERASE ETA; [GO:0003887] DNA-directed DNA polymerase activity; [GO:0003684] damaged DNA binding; [K03509] DNA polymerase eta subunit [EC:2.7.7.7] 19.08 0.7362
24 Mapoly0010s0132 [KOG4825] Component of synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine-binding glycoprotein (43kDa); [PF02151] UvrB/uvrC motif; [GO:0005515] protein binding; [PTHR13371] GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN; [PTHR13371:SF0] SUBFAMILY NOT NAMED 19.87 0.7397
25 Mapoly0097s0033 [PTHR10870] CELL CYCLE CHECKPOINT PROTEIN RAD1; [KOG3194] Checkpoint 9-1-1 complex, RAD1 component; [PF02144] Repair protein Rad1/Rec1/Rad17; [GO:0005634] nucleus; [K02830] cell cycle checkpoint protein [EC:3.1.11.2]; [GO:0006281] DNA repair; [3.1.11.2] Exodeoxyribonuclease III. 20.00 0.7592
26 Mapoly0011s0164 [GO:0005524] ATP binding; [PTHR24223:SF5] SUBFAMILY NOT NAMED; [GO:0016021] integral to membrane; [PTHR24223] FAMILY NOT NAMED; [PF00664] ABC transporter transmembrane region; [GO:0016887] ATPase activity; [GO:0006810] transport; [GO:0055085] transmembrane transport; [KOG0054] Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily; [GO:0042626] ATPase activity, coupled to transmembrane movement of substances; [PF00005] ABC transporter 20.59 0.6851
27 Mapoly0024s0018 [PTHR23147] SERINE/ARGININE RICH SPLICING FACTOR; [KOG4207] Predicted splicing factor, SR protein superfamily; [K12891] splicing factor, arginine/serine-rich 2; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 22.45 0.7796
28 Mapoly0079s0005 [GO:0008080] N-acetyltransferase activity; [GO:0016568] chromatin modification; [PF00583] Acetyltransferase (GNAT) family; [GO:0005634] nucleus; [GO:0004402] histone acetyltransferase activity; [GO:0016573] histone acetylation; [KOG2696] Histone acetyltransferase type b catalytic subunit; [GO:0006348] chromatin silencing at telomere; [2.3.1.48] Histone acetyltransferase.; [PTHR12046] HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT; [K11303] histone acetyltransferase 1 [EC:2.3.1.48]; [PF10394] Histone acetyl transferase HAT1 N-terminus 22.58 0.8025
29 Mapoly0023s0072 [3.1.27.-] Endoribonucleases producing other than 5'-phosphomonoesters.; [K13148] integrator complex subunit 11 [EC:3.1.27.-]; [PF07521] RNA-metabolising metallo-beta-lactamase; [PTHR11203] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF00753] Metallo-beta-lactamase superfamily; [PTHR11203:SF11] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF10996] Beta-Casp domain; [KOG1136] Predicted cleavage and polyadenylation specificity factor (CPSF subunit) 23.69 0.7713
30 Mapoly0052s0057 [PTHR22807] NOP2(YEAST)-RELATED NOL1/NOP2/FMU(SUN) DOMAIN-CONTAINING; [PTHR22807:SF16] SUN FAMILY PROTEIN-RELATED; [PF01189] NOL1/NOP2/sun family; [KOG2198] tRNA cytosine-5-methylases and related enzymes of the NOL1/NOP2/sun superfamily 24.49 0.7439
31 Mapoly0185s0017 [GO:0030915] Smc5-Smc6 complex; [PF08746] RING-like domain; [KOG4718] Non-SMC (structural maintenance of chromosomes) element 1 protein (NSE1); [PTHR20973] NON-SMC ELEMENT 1-RELATED; [PF07574] Nse1 non-SMC component of SMC5-6 complex; [GO:0006281] DNA repair; [PTHR20973:SF0] SUBFAMILY NOT NAMED 24.49 0.7964
32 Mapoly0089s0012 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 24.82 0.7775
33 Mapoly0009s0161 [PTHR15606:SF4] SUBFAMILY NOT NAMED; [PF00226] DnaJ domain; [PTHR15606] DNAJ HOMOLOG SUBFAMILY C MEMBER 8/LIPOPOLYSACCHARIDE SPECIFIC RESPONSE-7-RELATED; [KOG1150] Predicted molecular chaperone (DnaJ superfamily); [K09528] DnaJ homolog subfamily C member 8 28.28 0.6863
34 Mapoly0043s0128 [KOG0381] HMG box-containing protein; [GO:0003677] DNA binding; [PF00505] HMG (high mobility group) box; [PF01388] ARID/BRIGHT DNA binding domain; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [GO:0005622] intracellular 31.75 0.7700
35 Mapoly0079s0030 [KOG0543] FKBP-type peptidyl-prolyl cis-trans isomerase; [PTHR10516] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF13414] TPR repeat; [GO:0006457] protein folding; [PF00254] FKBP-type peptidyl-prolyl cis-trans isomerase 31.94 0.6859
36 Mapoly0032s0110 [PTHR16219] FAMILY NOT NAMED; [PF14735] HAUS augmin-like complex subunit 4; [GO:0051225] spindle assembly; [GO:0070652] HAUS complex; [PTHR16219:SF1] SUBFAMILY NOT NAMED 32.19 0.7081
37 Mapoly0059s0054 [GO:0006338] chromatin remodeling; [PTHR10019] SNF5; [GO:0000228] nuclear chromosome; [K11648] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; [PF04855] SNF5 / SMARCB1 / INI1 33.47 0.7389
38 Mapoly0117s0005 [K13109] IK cytokine; [PTHR12765] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [KOG2498] IK cytokine down-regulator of HLA class II; [PF07807] RED-like protein C-terminal region; [PTHR12765:SF5] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [GO:0005634] nucleus; [PF07808] RED-like protein N-terminal region 34.64 0.7747
39 Mapoly0009s0067 [PTHR31789] FAMILY NOT NAMED 36.08 0.7648
40 Mapoly0001s0028 [KOG1659] Class 2 transcription repressor NC2, alpha subunit (DRAP1); [GO:0005622] intracellular; [GO:0043565] sequence-specific DNA binding; [PTHR10252:SF5] DR1-ASSOCIATED COREPRESSOR; [PF00808] Histone-like transcription factor (CBF/NF-Y) and archaeal histone; [PTHR10252] HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED 36.50 0.7442
41 Mapoly0101s0017 [KOG1294] Apurinic/apyrimidinic endonuclease and related enzymes; [PTHR22748:SF1] AP ENDONUCLEASE; [GO:0006281] DNA repair; [PF03372] Endonuclease/Exonuclease/phosphatase family; [GO:0004518] nuclease activity; [PTHR22748] AP ENDONUCLEASE 36.93 0.7532
42 Mapoly0016s0006 [PTHR19923] WD40 REPEAT PROTEINPRL1/PRL2-RELATED; [PTHR19923:SF0] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [K12862] pleiotropic regulator 1; [KOG0285] Pleiotropic regulator 1; [PF00400] WD domain, G-beta repeat 37.42 0.7701
43 Mapoly0043s0064 [PF10979] Protein of unknown function (DUF2786) 40.19 0.7869
44 Mapoly0140s0032 [PTHR12748] ORIGIN RECOGNITION COMPLEX SUBUNIT 3; [PTHR12748:SF0] SUBFAMILY NOT NAMED; [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02605] origin recognition complex subunit 3; [PF07034] Origin recognition complex (ORC) subunit 3 N-terminus; [KOG2538] Origin recognition complex, subunit 3; [GO:0005664] nuclear origin of replication recognition complex; [PF02178] AT hook motif 40.30 0.7985
45 Mapoly0112s0002 [PF14750] Integrator complex subunit 2; [K13139] integrator complex subunit 2; [GO:0032039] integrator complex 40.69 0.7449
46 Mapoly0080s0039 [PTHR15081] NUCLEAR AUTOANTIGENIC SPERM PROTEIN (NASP)-RELATED; [PF13414] TPR repeat; [PF10516] SHNi-TPR 41.57 0.7723
47 Mapoly0045s0049 - 43.27 0.7293
48 Mapoly0004s0192 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [KOG0616] cAMP-dependent protein kinase catalytic subunit (PKA); [2.7.11.11] cAMP-dependent protein kinase.; [PTHR24353] CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE; [GO:0006468] protein phosphorylation; [K04345] protein kinase A [EC:2.7.11.11] 43.37 0.6991
49 Mapoly0154s0022 [GO:0003723] RNA binding; [GO:0016787] hydrolase activity; [PTHR23114] FAMILY NOT NAMED; [PF05026] Dcp2, box A domain; [GO:0030145] manganese ion binding; [PTHR23114:SF9] SUBFAMILY NOT NAMED; [3.-.-.-] Hydrolases.; [KOG2839] Diadenosine and diphosphoinositol polyphosphate phosphohydrolase; [PF00293] NUDIX domain; [K12613] mRNA-decapping enzyme subunit 2 [EC:3.-.-.-] 43.43 0.7380
50 Mapoly0073s0079 [GO:0046907] intracellular transport; [GO:0005643] nuclear pore; [PTHR23138] RAN BINDING PROTEIN; [PTHR23138:SF46] ABR034WP; [PF00638] RanBP1 domain; [PF08911] NUP50 (Nucleoporin 50 kDa) 43.71 0.7667
51 Mapoly0131s0025 [PF08324] PUL domain; [KOG0301] Phospholipase A2-activating protein (contains WD40 repeats); [PTHR19849] PHOSPHOLIPASE A-2-ACTIVATING PROTEIN; [PTHR19849:SF0] SUBFAMILY NOT NAMED; [K14018] phospholipase A-2-activating protein; [GO:0005515] protein binding; [PF09070] PFU (PLAA family ubiquitin binding); [PF00400] WD domain, G-beta repeat 45.50 0.7238
52 Mapoly0170s0030 [GO:0005524] ATP binding; [PTHR23073] 26S PROTEASE REGULATORY SUBUNIT; [KOG0726] 26S proteasome regulatory complex, ATPase RPT2; [PTHR23073:SF9] 26S PROTEASE REGULATORY SUBUNIT 4; [PF00004] ATPase family associated with various cellular activities (AAA); [K03062] 26S proteasome regulatory subunit T2 46.05 0.7314
53 Mapoly0069s0072 [GO:0005524] ATP binding; [GO:0008026] ATP-dependent helicase activity; [3.6.4.13] RNA helicase.; [PF13307] Helicase C-terminal domain; [PTHR11472] DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; [GO:0006139] nucleobase-containing compound metabolic process; [GO:0003676] nucleic acid binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [K11273] chromosome transmission fidelity protein 1 [EC:3.6.4.13] 46.37 0.7647
54 Mapoly0001s0446 - 48.34 0.7663
55 Mapoly0116s0041 [PF13297] Telomere stability C-terminal; [PTHR12786:SF2] SPLICING FACTOR 3A; [PF12108] Splicing factor SF3a60 binding domain; [KOG2636] Splicing factor 3a, subunit 3; [PTHR12786] SPLICING FACTOR SF3A-RELATED; [K12827] splicing factor 3A subunit 3; [PF11931] Domain of unknown function (DUF3449) 48.86 0.7729
56 Mapoly0037s0034 [K10744] ribonuclease H2 subunit B; [PTHR13383] FAMILY NOT NAMED; [PF09468] Ydr279p protein family (RNase H2 complex component); [GO:0005634] nucleus 49.14 0.7822
57 Mapoly0062s0008 [PF02295] Adenosine deaminase z-alpha domain; [GO:0003723] RNA binding; [GO:0003726] double-stranded RNA adenosine deaminase activity 49.61 0.7279
58 Mapoly0033s0067 [KOG2611] Neurochondrin/leucine-rich protein (Neurochondrin); [PTHR13109] NEUROCHONDRIN; [PF05536] Neurochondrin 49.84 0.7362
59 Mapoly0045s0061 [KOG1081] Transcription factor NSD1 and related SET domain proteins; [GO:0005515] protein binding; [PF00856] SET domain; [PTHR22884] SET DOMAIN PROTEINS 50.53 0.7686
60 Mapoly0197s0019 [PTHR10751] GUANYLATE BINDING PROTEIN; [PTHR10751:SF2] GUANYLATE BINDING PROTEIN; [PF02263] Guanylate-binding protein, N-terminal domain; [GO:0003924] GTPase activity; [GO:0005525] GTP binding; [PF02841] Guanylate-binding protein, C-terminal domain 50.74 0.7297
61 Mapoly0008s0044 - 52.37 0.6851
62 Mapoly0051s0073 [PF14675] FANCI solenoid 1; [PTHR21818:SF0] SUBFAMILY NOT NAMED; [PF14680] FANCI helical domain 2; [KOG4553] Uncharacterized conserved protein; [K10895] fanconi anemia group I protein; [PF14679] FANCI helical domain 1; [GO:0006281] DNA repair; [PF14678] FANCI solenoid 4; [PTHR21818] BC025462 PROTEIN; [PF14676] FANCI solenoid 2 52.48 0.7707
63 Mapoly0015s0073 [PF12780] P-loop containing dynein motor region D4; [PF12774] Hydrolytic ATP binding site of dynein motor region D1; [PF12775] P-loop containing dynein motor region D3; [GO:0005858] axonemal dynein complex; [GO:0030286] dynein complex; [PTHR10676] DYNEIN HEAVY CHAIN FAMILY PROTEIN; [PF03028] Dynein heavy chain and region D6 of dynein motor; [GO:0016887] ATPase activity; [KOG3595] Dyneins, heavy chain; [PF12777] Microtubule-binding stalk of dynein motor; [GO:0007018] microtubule-based movement; [PF08393] Dynein heavy chain, N-terminal region 2; [PF12781] ATP-binding dynein motor region D5; [GO:0003341] cilium movement; [PTHR10676:SF138] DYNEIN HEAVY CHAIN FAMILY PROTEIN; [GO:0003777] microtubule motor activity 52.50 0.7281
64 Mapoly0003s0009 [GO:0005515] protein binding; [PTHR18763] WD-REPEAT PROTEIN 18; [PF00400] WD domain, G-beta repeat 53.31 0.7341
65 Mapoly0084s0054 [K03029] 26S proteasome regulatory subunit N10; [PF02809] Ubiquitin interaction motif; [PF13519] von Willebrand factor type A domain; [GO:0006511] ubiquitin-dependent protein catabolic process; [PTHR10223] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4; [GO:0008540] proteasome regulatory particle, base subcomplex; [KOG2884] 26S proteasome regulatory complex, subunit RPN10/PSMD4 54.85 0.7617
66 Mapoly0084s0055 [GO:0005524] ATP binding; [KOG0744] AAA+-type ATPase; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23077] AAA-FAMILY ATPASE 56.32 0.7535
67 Mapoly0016s0080 [K14399] polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]; [PF03205] Molybdopterin guanine dinucleotide synthesis protein B; [KOG2749] mRNA cleavage and polyadenylation factor IA/II complex, subunit CLP1; [2.7.1.78] Polynucleotide 5'-hydroxyl-kinase.; [PTHR12755] CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P; [PF06807] Pre-mRNA cleavage complex II protein Clp1 56.39 0.7541
68 Mapoly0086s0067 [GO:0005524] ATP binding; [GO:0032300] mismatch repair complex; [KOG1979] DNA mismatch repair protein - MLH1 family; [PTHR10073] DNA MISMATCH REPAIR PROTEIN (MLH, PMS, MUTL); [PTHR10073:SF12] DNA MISMATCH REPAIR PROTEIN MUTL; [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [K08734] DNA mismatch repair protein MLH1; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01119] DNA mismatch repair protein, C-terminal domain 56.43 0.6867
69 Mapoly0099s0053 [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 57.45 0.7573
70 Mapoly0030s0009 [PF00505] HMG (high mobility group) box; [KOG0526] Nucleosome-binding factor SPN, POB3 subunit; [PF03531] Structure-specific recognition protein (SSRP1); [PTHR13711:SF39] SUBFAMILY NOT NAMED; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [PF08512] Histone chaperone Rttp106-like; [K09272] structure-specific recognition protein 1 58.79 0.7610
71 Mapoly0084s0053 [K10606] E3 ubiquitin-protein ligase FANCL [EC:6.3.2.19]; [6.3.2.19] Ubiquitin--protein ligase.; [GO:0006281] DNA repair; [GO:0043240] Fanconi anaemia nuclear complex; [PTHR13206:SF0] SUBFAMILY NOT NAMED; [PTHR13206] UBIQUITIN LIGASE PROTEIN PHF9 (FANCONI ANEMIA GROUP L PROTEIN); [GO:0004842] ubiquitin-protein ligase activity; [PF09765] WD-repeat region; [PF11793] FANCL C-terminal domain; [KOG3268] Predicted E3 ubiquitin ligase 58.80 0.6727
72 Mapoly0060s0105 [PTHR24012] FAMILY NOT NAMED; [KOG4207] Predicted splicing factor, SR protein superfamily; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 58.97 0.7561
73 Mapoly0003s0057 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination 59.37 0.7793
74 Mapoly0014s0064 [PTHR10552] U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A; [K11092] U2 small nuclear ribonucleoprotein A'; [KOG1644] U2-associated snRNP A' protein; [PF14580] Leucine-rich repeat 61.04 0.7573
75 Mapoly0001s0392 [KOG0121] Nuclear cap-binding protein complex, subunit CBP20 (RRM superfamily); [GO:0000339] RNA cap binding; [GO:0045292] mRNA cis splicing, via spliceosome; [K12883] nuclear cap-binding protein subunit 2; [GO:0003676] nucleic acid binding; [GO:0005846] nuclear cap binding complex; [PTHR18847] 20 KD NUCLEAR CAP BINDING PROTEIN; [PTHR18847:SF0] SUBFAMILY NOT NAMED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 63.61 0.7216
76 Mapoly0014s0028 [PTHR22942:SF8] DNA REPAIR PROTEIN RAD51 HOMOLOG 4 (R51H4); [KOG1434] Meiotic recombination protein Dmc1; [PTHR22942] RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER; [PF08423] Rad51 65.45 0.6745
77 Mapoly0051s0023 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III 65.51 0.7768
78 Mapoly0033s0045 - 65.80 0.7223
79 Mapoly0221s0003 - 67.14 0.7632
80 Mapoly0009s0203 - 68.59 0.7352
81 Mapoly0074s0043 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [GO:0003729] mRNA binding 70.63 0.7555
82 Mapoly0029s0012 [GO:0005524] ATP binding; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [KOG0329] ATP-dependent RNA helicase; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding 71.75 0.7642
83 Mapoly0068s0001 [K10736] minichromosome maintenance protein 10; [GO:0006260] DNA replication; [PTHR13454] FAMILY NOT NAMED; [PF09329] Primase zinc finger; [GO:0005634] nucleus 73.42 0.7606
84 Mapoly0029s0119 - 74.22 0.7053
85 Mapoly0015s0045 [KOG0533] RRM motif-containing protein; [PTHR19965] RNA AND EXPORT FACTOR BINDING PROTEIN; [K12881] THO complex subunit 4; [PF13865] C-terminal duplication domain of Friend of PRMT1; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 75.34 0.7366
86 Mapoly0077s0014 [PTHR21148:SF12] PHOSDUCIN; [KOG1672] ATP binding protein; [GO:0045454] cell redox homeostasis; [PTHR21148] PHOSDUCIN-RELATED; [PF00085] Thioredoxin 75.76 0.6856
87 Mapoly0024s0122 [PTHR30060] INNER MEMBRANE PROTEIN; [PF09745] Coiled-coil domain-containing protein 55 (DUF2040); [PTHR30060:SF0] INNER MEMBRANE PROTEIN 79.18 0.6625
88 Mapoly0054s0011 [PF06220] U1 zinc finger; [K13152] U11/U12 small nuclear ribonucleoprotein 20 kDa protein; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0008270] zinc ion binding; [KOG3454] U1 snRNP-specific protein C; [PTHR16465] NUCLEASE-RELATED; [GO:0046872] metal ion binding; [PTHR16465:SF0] SUBFAMILY NOT NAMED 79.52 0.6908
89 Mapoly0027s0013 [KOG4487] Uncharacterized conserved protein; [PF09696] Ctf8; [K11270] chromosome transmission fidelity protein 8 80.22 0.7633
90 Mapoly0010s0010 [GO:0005643] nuclear pore; [PF13874] Nucleoporin complex subunit 54; [PTHR13000] NUCLEOPORIN P54; [KOG3091] Nuclear pore complex, p54 component (sc Nup57) 80.60 0.7447
91 Mapoly0015s0164 [GO:0003677] DNA binding; [PF02362] B3 DNA binding domain; [PTHR31391] FAMILY NOT NAMED 80.90 0.7423
92 Mapoly0013s0062 [GO:0003677] DNA binding; [PTHR15348:SF0] SUBFAMILY NOT NAMED; [PF01388] ARID/BRIGHT DNA binding domain; [GO:0005622] intracellular; [PTHR15348] AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN (ARID DOMAIN- CONTAINING PROTEIN) (DEAD RINGER PROTEIN) (B-CELL REGULATOR OF IGH TRANSCRIPTION) (BRIGHT) 81.39 0.7480
93 Mapoly0157s0022 [PTHR13889:SF11] SUBFAMILY NOT NAMED; [K10599] pre-mRNA-processing factor 19 [EC:6.3.2.19]; [PF08606] Prp19/Pso4-like; [GO:0005515] protein binding; [KOG0289] mRNA splicing factor; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR13889] PRE-MRNA SPLICING FACTOR PRP19-RELATED; [PF00400] WD domain, G-beta repeat 84.23 0.6844
94 Mapoly0011s0202 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain 84.38 0.7666
95 Mapoly0123s0035 [PTHR14614] HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; [PF10294] Putative methyltransferase; [KOG3201] Uncharacterized conserved protein 84.73 0.6460
96 Mapoly0002s0133 [GO:0007076] mitotic chromosome condensation; [PTHR13108] FAMILY NOT NAMED; [PF05786] Condensin complex subunit 2; [KOG2328] Chromosome condensation complex Condensin, subunit H; [GO:0000796] condensin complex; [K06676] condensin complex subunit 2 85.32 0.7581
97 Mapoly0061s0010 [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10536] DNA PRIMASE SMALL SUBUNIT; [KOG2851] Eukaryotic-type DNA primase, catalytic (small) subunit; [K02684] DNA primase small subunit [EC:2.7.7.-]; [2.7.7.-] Nucleotidyltransferases.; [PF01896] Eukaryotic and archaeal DNA primase small subunit 85.70 0.7591
98 Mapoly0014s0097 [PF13414] TPR repeat; [KOG1308] Hsp70-interacting protein Hip/Transient component of progesterone receptor complexes and an Hsp70-binding protein; [PTHR22904:SF34] HSC70-INTERACTING PROTEIN; [PTHR22904] TPR REPEAT CONTAINING PROTEIN 85.93 0.7450
99 Mapoly0131s0021 [PTHR13119] FAMILY NOT NAMED; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 86.68 0.6255
100 Mapoly0209s0009 [PF04266] ASCH domain 87.57 0.6846
101 Mapoly0002s0169 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [K06632] wee1-like protein kinase [EC:2.7.11.1]; [PTHR11042] EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE (EIF2-ALPHA KINASE)-RELATED; [KOG0601] Cyclin-dependent kinase WEE1 87.87 0.7510
102 Mapoly0057s0106 [K08288] protein kinase C substrate 80K-H; [PTHR12630:SF4] PROTEIN KINASE C SUBSTRATE 80K-H; [KOG2397] Protein kinase C substrate, 80 KD protein, heavy chain; [PTHR12630] N-LINKED OLIGOSACCHARIDE PROCESSING; [PF12999] Glucosidase II beta subunit-like; [PF13015] Glucosidase II beta subunit-like protein 88.36 0.6151
103 Mapoly0001s0472 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED 88.86 0.7572
104 Mapoly0113s0020 [GO:0003677] DNA binding; [PTHR12604:SF2] KU P70 DNA HELICASE; [K10884] ATP-dependent DNA helicase 2 subunit 1; [GO:0042162] telomeric DNA binding; [PF03730] Ku70/Ku80 C-terminal arm; [PF02735] Ku70/Ku80 beta-barrel domain; [PF03731] Ku70/Ku80 N-terminal alpha/beta domain; [GO:0043564] Ku70:Ku80 complex; [GO:0005634] nucleus; [GO:0004003] ATP-dependent DNA helicase activity; [GO:0003676] nucleic acid binding; [KOG2327] DNA-binding subunit of a DNA-dependent protein kinase (Ku70 autoantigen); [PTHR12604] KU AUTOANTIGEN DNA HELICASE; [GO:0003684] damaged DNA binding; [GO:0006303] double-strand break repair via nonhomologous end joining; [PF02037] SAP domain; [GO:0000723] telomere maintenance 89.19 0.6909
105 Mapoly0035s0108 [GO:0005524] ATP binding; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23074] AAA ATPASE; [KOG0740] AAA+-type ATPase; [PF09336] Vps4 C terminal oligomerisation domain; [PTHR23074:SF17] FIDGETIN LIKE-1 89.80 0.7370
106 Mapoly0174s0023 [GO:0006396] RNA processing; [PTHR13734] TRNA-NUCLEOTIDYLTRANSFERASE/POLY(A) POLYMERASE FAMILY MEMBER; [GO:0003723] RNA binding; [PF01743] Poly A polymerase head domain; [KOG2159] tRNA nucleotidyltransferase/poly(A) polymerase; [GO:0016779] nucleotidyltransferase activity; [PTHR13734:SF5] POLY(A) POLYMERASE 90.07 0.7000
107 Mapoly0112s0022 [PTHR19932] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; [GO:0005515] protein binding; [KOG1274] WD40 repeat protein; [K11274] chromosome transmission fidelity protein 4; [PTHR19932:SF10] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN 1; [PF00400] WD domain, G-beta repeat; [PF12341] Protein of unknown function (DUF3639) 92.95 0.7581
108 Mapoly0009s0086 [PTHR10741:SF4] PUTATIVE UNCHARACTERIZED PROTEIN ORF-C08_005 (PUTATIVE UNCHARACTERIZED PROTEIN); [PTHR10741] TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X; [GO:0043565] sequence-specific DNA binding; [KOG3066] Translin-associated protein X; [PF01997] Translin family 93.45 0.6751
109 Mapoly0016s0021 - 93.91 0.6305
110 Mapoly0011s0104 [GO:0003755] peptidyl-prolyl cis-trans isomerase activity; [PTHR11071] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF00160] Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; [GO:0000413] protein peptidyl-prolyl isomerization; [KOG0546] HSP90 co-chaperone CPR7/Cyclophilin; [GO:0006457] protein folding 95.66 0.7073
111 Mapoly0001s0378 [PTHR32086] FAMILY NOT NAMED; [K10891] fanconi anemia group D2 protein; [GO:0006281] DNA repair; [KOG4712] Uncharacterized conserved protein; [PF14631] Fanconi anaemia protein FancD2 nuclease 97.77 0.7388
112 Mapoly0003s0120 [GO:0003677] DNA binding; [PTHR12708:SF0] SUBFAMILY NOT NAMED; [GO:0006260] DNA replication; [PF12213] DNA polymerases epsilon N terminal; [2.7.7.7] DNA-directed DNA polymerase.; [PTHR12708] DNA POLYMERASE EPSILON SUBUNIT B; [KOG3818] DNA polymerase epsilon, subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [GO:0003887] DNA-directed DNA polymerase activity; [K02325] DNA polymerase epsilon subunit 2 [EC:2.7.7.7] 98.04 0.7364
113 Mapoly0101s0048 [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat 98.08 0.7511
114 Mapoly0005s0138 - 98.49 0.7318
115 Mapoly0055s0064 - 98.67 0.7544
116 Mapoly0005s0051 [GO:0003723] RNA binding; [GO:0000339] RNA cap binding; [GO:0045292] mRNA cis splicing, via spliceosome; [GO:0051028] mRNA transport; [PF02854] MIF4G domain; [GO:0005515] protein binding; [KOG1104] Nuclear cap-binding complex, subunit NCBP1/CBP80; [K12882] nuclear cap-binding protein subunit 1; [GO:0016070] RNA metabolic process; [PTHR12412] CAP BINDING PROTEIN; [GO:0005846] nuclear cap binding complex; [PF09090] MIF4G like; [PF09088] MIF4G like 98.95 0.7515
117 Mapoly0034s0011 [PF09133] SANTA (SANT Associated) 98.95 0.7480
118 Mapoly0037s0121 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) 99.32 0.7142
119 Mapoly0130s0046 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF14493] Helix-turn-helix domain; [PF09382] RQC domain; [K10900] werner syndrome ATP-dependent helicase [EC:3.6.4.12]; [KOG0353] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 99.53 0.7399
120 Mapoly0108s0031 [GO:0005524] ATP binding; [K04499] RuvB-like protein 1 (pontin 52); [KOG1942] DNA helicase, TBP-interacting protein; [PF06068] TIP49 C-terminus; [GO:0043141] ATP-dependent 5'-3' DNA helicase activity; [GO:0003678] DNA helicase activity; [PTHR11093] RUVB-RELATED REPTIN AND PONTIN 99.99 0.7328
121 Mapoly0032s0034 - 100.40 0.7364
122 Mapoly0076s0033 [PF10444] Nbl1 / Borealin N terminal 100.58 0.7482
123 Mapoly0166s0018 [K10739] replication factor A2; [KOG3108] Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit; [PF08784] Replication protein A C terminal; [PTHR13989] REPLICATION PROTEIN A-RELATED; [GO:0003676] nucleic acid binding; [PF01336] OB-fold nucleic acid binding domain 101.65 0.7528
124 Mapoly0002s0134 [GO:0005524] ATP binding; [GO:0006165] nucleoside diphosphate phosphorylation; [GO:0004550] nucleoside diphosphate kinase activity; [PF00334] Nucleoside diphosphate kinase; [K00940] nucleoside-diphosphate kinase [EC:2.7.4.6]; [PTHR11349] NUCLEOSIDE DIPHOSPHATE KINASE; [GO:0006241] CTP biosynthetic process; [GO:0006228] UTP biosynthetic process; [KOG0888] Nucleoside diphosphate kinase; [2.7.4.6] Nucleoside-diphosphate kinase.; [GO:0006183] GTP biosynthetic process 102.06 0.7192
125 Mapoly0014s0073 [KOG1663] O-methyltransferase; [GO:0008171] O-methyltransferase activity; [PTHR10509] O-METHYLTRANSFERASE-RELATED; [PF01596] O-methyltransferase 102.24 0.6863
126 Mapoly0051s0067 [PF00651] BTB/POZ domain; [PTHR24411] FAMILY NOT NAMED; [PF00917] MATH domain; [GO:0005515] protein binding; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 104.36 0.6873
127 Mapoly0001s0197 [K10733] GINS complex subunit 2; [GO:0006260] DNA replication; [PF05916] GINS complex protein; [GO:0005634] nucleus; [KOG4071] Uncharacterized conserved protein; [PTHR12772] DNA REPLICATION COMPLEX GINS PROTEIN PSF2 105.08 0.6936
128 Mapoly0038s0101 [K12837] splicing factor U2AF 65 kDa subunit; [PTHR23139] RNA-BINDING PROTEIN; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG0120] Splicing factor U2AF, large subunit (RRM superfamily); [GO:0003676] nucleic acid binding; [PTHR23139:SF9] SPLICING FACTOR U2AF LARGE SUBUNIT; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 105.94 0.7366
129 Mapoly0004s0008 - 106.09 0.7002
130 Mapoly0016s0052 [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat 106.49 0.6348
131 Mapoly0001s0348 [KOG1342] Histone deacetylase complex, catalytic component RPD3; [PF00850] Histone deacetylase domain; [PTHR10625] HISTONE DEACETYLASE 106.80 0.6903
132 Mapoly0027s0185 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF39] CDC2-RELATED PROTEIN KINASE; [KOG0600] Cdc2-related protein kinase; [K08819] Cdc2-related kinase, arginine/serine-rich [EC:2.7.11.22]; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 107.66 0.7204
133 Mapoly0010s0030 [PTHR22880] FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; [GO:0005515] protein binding; [PF00439] Bromodomain 108.19 0.7156
134 Mapoly0009s0039 [GO:0030915] Smc5-Smc6 complex; [KOG2866] Uncharacterized conserved protein; [PTHR16140:SF0] SUBFAMILY NOT NAMED; [PTHR16140] UNCHARACTERIZED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08743] Nse4 C-terminal 111.31 0.7464
135 Mapoly0034s0031 [GO:0007094] mitotic spindle assembly checkpoint; [K06638] mitotic spindle assembly checkpoint protein MAD1; [KOG4593] Mitotic checkpoint protein MAD1; [PTHR23168] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 (MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1); [PF05557] Mitotic checkpoint protein; [PTHR23168:SF0] SUBFAMILY NOT NAMED 112.32 0.7436
136 Mapoly0073s0063 [GO:0016020] membrane; [GO:0005524] ATP binding; [GO:0017038] protein import; [PF07516] SecA Wing and Scaffold domain; [PTHR30612] SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM; [PF07517] SecA DEAD-like domain; [PF01043] SecA preprotein cross-linking domain; [K03070] preprotein translocase subunit SecA 112.38 0.6305
137 Mapoly0214s0009 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 113.48 0.7021
138 Mapoly0118s0024 [PTHR22840] FAMILY NOT NAMED; [GO:0005515] protein binding; [K14406] cleavage stimulation factor subunit 1; [KOG0640] mRNA cleavage stimulating factor complex; subunit 1; [PF00400] WD domain, G-beta repeat 115.37 0.6684
139 Mapoly0104s0010 [PTHR17204:SF5] PRE-MRNA PROCESSING PROTEIN PRP39-RELATED; [K13217] pre-mRNA-processing factor 39; [KOG1258] mRNA processing protein; [GO:0006397] mRNA processing; [GO:0005634] nucleus; [PF05843] Suppressor of forked protein (Suf); [PTHR17204] PRE-MRNA PROCESSING PROTEIN PRP39-RELATED 115.46 0.7169
140 Mapoly0049s0118 [PTHR32002] FAMILY NOT NAMED; [PF02042] RWP-RK domain 117.17 0.6958
141 Mapoly0001s0015 [PTHR13555] C2H2 ZINC FINGER CGI-62-RELATED 117.20 0.6861
142 Mapoly0001s0457 [PTHR14360:SF1] UNCHARACTERIZED; [PF07798] Protein of unknown function (DUF1640); [KOG3156] Uncharacterized membrane protein; [PTHR14360] UNCHARACTERIZED 117.36 0.6888
143 Mapoly0051s0085 [KOG2267] Eukaryotic-type DNA primase, large subunit; [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10537] DNA PRIMASE LARGE SUBUNIT; [K02685] DNA primase large subunit [EC:2.7.7.-]; [PF04104] Eukaryotic and archaeal DNA primase, large subunit; [2.7.7.-] Nucleotidyltransferases. 117.77 0.7361
144 Mapoly0005s0155 [PF03517] Regulator of volume decrease after cellular swelling; [GO:0006821] chloride transport; [GO:0005829] cytosol; [GO:0005886] plasma membrane; [GO:0006884] cell volume homeostasis; [K05019] chloride channel, nucleotide-sensitive, 1A; [GO:0034709] methylosome; [GO:0034715] pICln-Sm protein complex; [KOG3238] Chloride ion current inducer protein; [PTHR21399] CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN; [GO:0000387] spliceosomal snRNP assembly 119.03 0.7053
145 Mapoly0109s0027 - 119.29 0.6643
146 Mapoly0093s0043 - 119.32 0.7242
147 Mapoly0004s0128 [GO:0005524] ATP binding; [K08864] tousled-like kinase [EC:2.7.11.1]; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PTHR22974] MIXED LINEAGE PROTEIN KINASE; [KOG1151] Tousled-like protein kinase 121.33 0.7177
148 Mapoly0059s0052 [KOG0331] ATP-dependent RNA helicase; [GO:0005524] ATP binding; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding 121.74 0.6411
149 Mapoly0032s0081 [GO:0008641] small protein activating enzyme activity; [GO:0045116] protein neddylation; [GO:0005524] ATP binding; [PTHR10953:SF6] UBIQUITIN-ACTIVATING ENZYME E1C (NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT); [KOG2015] NEDD8-activating complex, catalytic component UBA3; [PF08825] E2 binding domain; [GO:0016881] acid-amino acid ligase activity; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [K10686] ubiquitin-activating enzyme E1 C [EC:6.3.2.19] 123.69 0.6939
150 Mapoly0008s0073 [PTHR14604:SF3] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [KOG0285] Pleiotropic regulator 1; [PTHR14604] WD40 REPEAT PF20; [PF00400] WD domain, G-beta repeat 123.84 0.6296
151 Mapoly0173s0011 [PF00183] Hsp90 protein; [GO:0005524] ATP binding; [GO:0006950] response to stress; [KOG0020] Endoplasmic reticulum glucose-regulated protein (GRP94/endoplasmin), HSP90 family; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [GO:0006457] protein folding; [K04079] molecular chaperone HtpG; [PTHR11528] HEAT SHOCK PROTEIN 90; [GO:0051082] unfolded protein binding 123.87 0.7247
152 Mapoly0068s0080 [PF07719] Tetratricopeptide repeat; [KOG0543] FKBP-type peptidyl-prolyl cis-trans isomerase; [PTHR10516] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF13414] TPR repeat; [GO:0006457] protein folding; [PF00254] FKBP-type peptidyl-prolyl cis-trans isomerase 124.10 0.5850
153 Mapoly0105s0026 - 124.71 0.7023
154 Mapoly0154s0005 [PTHR22852] LETHAL(2)DENTICLELESS PROTEIN (RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN); [KOG0265] U5 snRNP-specific protein-like factor and related proteins; [K11790] denticleless; [GO:0005515] protein binding; [PF00400] WD domain, G-beta repeat 127.94 0.7366
155 Mapoly0007s0146 [KOG4374] RNA-binding protein Bicaudal-C; [PTHR15457] SEC-23 INTERACTING PROTEIN P125; [PF00536] SAM domain (Sterile alpha motif) 128.16 0.6804
156 Mapoly0066s0099 [GO:0005840] ribosome; [PF01165] Ribosomal protein S21; [PTHR21109:SF0] SUBFAMILY NOT NAMED; [PTHR21109] MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S21; [GO:0003735] structural constituent of ribosome; [GO:0006412] translation 128.18 0.6564
157 Mapoly0052s0111 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG4206] Spliceosomal protein snRNP-U1A/U2B; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED 129.35 0.7108
158 Mapoly0092s0013 [GO:0003723] RNA binding; [PTHR13326] TRNA PSEUDOURIDINE SYNTHASE D; [GO:0001522] pseudouridine synthesis; [GO:0009451] RNA modification; [PF01142] tRNA pseudouridine synthase D (TruD); [GO:0009982] pseudouridine synthase activity; [KOG2339] Uncharacterized conserved protein 129.87 0.7007
159 Mapoly0042s0049 - 131.77 0.7347
160 Mapoly0070s0095 [PTHR23215] ZINC FINGER PROTEIN 207; [KOG2893] Zn finger protein 133.00 0.7101
161 Mapoly0045s0042 [KOG2475] CDC45 (cell division cycle 45)-like protein; [GO:0006270] DNA replication initiation; [PF02724] CDC45-like protein; [PTHR10507:SF0] CDC45-RELATED PROTEIN; [PTHR10507] CDC45-RELATED PROTEIN; [K06628] cell division control protein 45 133.97 0.7362
162 Mapoly0120s0022 [PTHR10588] FAMILY NOT NAMED; [KOG1644] U2-associated snRNP A' protein; [PF12799] Leucine Rich repeats (2 copies); [PTHR10588:SF7] LEUCINE-RICH REPEAT-CONTAINING PROTEIN 50 134.09 0.7048
163 Mapoly0051s0060 [PTHR31399:SF0] SUBFAMILY NOT NAMED; [PF03121] Herpesviridae UL52/UL70 DNA primase; [GO:0006260] DNA replication; [GO:0003896] DNA primase activity; [PTHR31399] FAMILY NOT NAMED 134.70 0.7108
164 Mapoly0127s0019 - 136.15 0.7264
165 Mapoly0005s0161 [GO:0003677] DNA binding; [PTHR13451:SF0] SUBFAMILY NOT NAMED; [3.1.22.-] Endodeoxyribonucleases producing other than 5'-phosphomonoesters.; [K08991] crossover junction endonuclease MUS81 [EC:3.1.22.-]; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PF02732] ERCC4 domain 136.46 0.6879
166 Mapoly0024s0112 [GO:0005643] nuclear pore; [KOG1964] Nuclear pore complex, rNup107 component (sc Nup84); [PTHR13003] NUP107-RELATED; [GO:0006810] transport; [PF04121] Nuclear pore protein 84 / 107; [K14301] nuclear pore complex protein Nup107 136.75 0.7272
167 Mapoly0069s0077 [PTHR11736:SF14] MAGE-RELATED; [PTHR11736] MELANOMA-ASSOCIATED ANTIGEN (MAGE ANTIGEN); [PF01454] MAGE family; [KOG4562] Uncharacterized conserved protein (tumor-rejection antigen MAGE in humans) 137.93 0.6576
168 Mapoly0016s0206 [GO:0005515] protein binding; [PF14560] Ubiquitin-like domain; [PF01302] CAP-Gly domain; [KOG3206] Alpha-tubulin folding cofactor B; [PTHR18916] DYNACTIN 1-RELATED MICROTUBULE-BINDING 138.00 0.6647
169 Mapoly0001s0105 [K02541] minichromosome maintenance protein 3; [KOG0479] DNA replication licensing factor, MCM3 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11630:SF46] DNA REPLICATION LICENSING FACTOR MCM3; [PF00493] MCM2/3/5 family; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 138.29 0.7369
170 Mapoly0098s0043 [PF12717] non-SMC mitotic condensation complex subunit 1; [GO:0007076] mitotic chromosome condensation; [K11491] condensin-2 complex subunit D3; [PTHR14222:SF1] CONDENSIN; [PTHR14222] CONDENSIN 139.21 0.7310
171 Mapoly0027s0105 - 139.52 0.6900
172 Mapoly0021s0077 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [KOG0796] Spliceosome subunit; [GO:0003729] mRNA binding 139.91 0.7147
173 Mapoly0213s0004 [PTHR24012] FAMILY NOT NAMED; [KOG0226] RNA-binding proteins; [GO:0003676] nucleic acid binding; [PTHR24012:SF41] SUBFAMILY NOT NAMED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 140.76 0.6703
174 Mapoly0165s0024 [GO:0006338] chromatin remodeling; [GO:0043968] histone H2A acetylation; [PF00249] Myb-like DNA-binding domain; [K11324] DNA methyltransferase 1-associated protein 1; [GO:0043967] histone H4 acetylation; [KOG2656] DNA methyltransferase 1-associated protein-1; [GO:0003682] chromatin binding; [PTHR12855] FAMILY NOT NAMED; [GO:0035267] NuA4 histone acetyltransferase complex; [GO:0006281] DNA repair; [PTHR12855:SF10] SUBFAMILY NOT NAMED 141.46 0.7132
175 Mapoly0098s0009 [K01104] protein-tyrosine phosphatase [EC:3.1.3.48]; [PF00581] Rhodanese-like domain; [PTHR10828:SF17] M-PHASE INDUCER PHOSPHATASE (DUAL SPECIFICITY PHOSPHATASE CDC25); [PTHR10828] M-PHASE INDUCER PHOSPHATASE (DUAL SPECIFICITY PHOSPHATASE CDC25); [3.1.3.48] Protein-tyrosine-phosphatase. 141.63 0.7219
176 Mapoly0097s0064 [PTHR13710:SF1] ROTHMUND-THOMSON SYNDROME DNA HELICASE RECQ4; [GO:0005524] ATP binding; [PF11719] DNA replication and checkpoint protein; [K10730] ATP-dependent DNA helicase Q4 [EC:3.6.4.12]; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [GO:0003676] nucleic acid binding; [PF02037] SAP domain 142.39 0.7275
177 Mapoly0114s0041 [GO:0003755] peptidyl-prolyl cis-trans isomerase activity; [PTHR11071] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF00160] Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; [GO:0000413] protein peptidyl-prolyl isomerization; [KOG0879] U-snRNP-associated cyclophilin type peptidyl-prolyl cis-trans isomerase; [GO:0006457] protein folding; [5.2.1.8] Peptidylprolyl isomerase.; [K09567] peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]; [PTHR11071:SF58] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE H, PPIH 142.53 0.6740
178 Mapoly0077s0044 [GO:0045454] cell redox homeostasis; [PF00085] Thioredoxin; [PTHR18929] PROTEIN DISULFIDE ISOMERASE 142.95 0.6385
179 Mapoly0016s0108 [GO:0005524] ATP binding; [K10755] replication factor C subunit 2/4; [KOG0991] Replication factor C, subunit RFC2; [PTHR11669] REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08542] Replication factor C C-terminal domain 142.97 0.7096
180 Mapoly0033s0057 [2.3.1.-] Transferring groups other than amino-acyl groups.; [PTHR11076:SF1] ESTABLISHMENT OF COHESION 1 (ECO1) HOMOLOG; [PF13880] ESCO1/2 acetyl-transferase; [PF13878] zinc-finger of acetyl-transferase ESCO; [KOG3014] Protein involved in establishing cohesion between sister chromatids during DNA replication; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [K11268] N-acetyltransferase [EC:2.3.1.-] 143.48 0.7362
181 Mapoly0004s0250 [GO:0005643] nuclear pore; [PF07817] GLE1-like protein; [GO:0016973] poly(A)+ mRNA export from nucleus; [KOG2412] Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor; [PTHR12960:SF0] SUBFAMILY NOT NAMED; [PTHR12960] GLE-1-RELATED 144.88 0.7122
182 Mapoly0086s0078 [GO:0003677] DNA binding; [GO:0006275] regulation of DNA replication; [GO:0030337] DNA polymerase processivity factor activity; [PTHR11352] PROLIFERATING CELL NUCLEAR ANTIGEN; [PF00705] Proliferating cell nuclear antigen, N-terminal domain; [KOG1636] DNA polymerase delta processivity factor (proliferating cell nuclear antigen); [PF02747] Proliferating cell nuclear antigen, C-terminal domain 144.99 0.7090
183 Mapoly0071s0102 [PF03645] Tctex-1 family; [PTHR21255:SF7] SUBFAMILY NOT NAMED; [PTHR21255] T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN; [KOG4108] Dynein light chain 145.42 0.7036
184 Mapoly0459s0001 - 145.49 0.6257
185 Mapoly0081s0071 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [PF00628] PHD-finger; [GO:0005515] protein binding; [PF12738] twin BRCT domain; [GO:0046872] metal ion binding 145.70 0.7236
186 Mapoly0032s0121 [PTHR22976] BIOTIN SYNTHASE; [PTHR22976:SF4] SUBFAMILY NOT NAMED; [PF04055] Radical SAM superfamily; [GO:0003824] catalytic activity; [GO:0051536] iron-sulfur cluster binding 146.82 0.6543
187 Mapoly0013s0016 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR31614] FAMILY NOT NAMED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08661] Replication factor A protein 3; [GO:0006310] DNA recombination 148.24 0.7151
188 Mapoly0051s0027 [GO:0003677] DNA binding; [PF02178] AT hook motif 149.32 0.6488
189 Mapoly0065s0024 - 150.04 0.6503
190 Mapoly0075s0022 [KOG0482] DNA replication licensing factor, MCM7 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [K02210] minichromosome maintenance protein 7 (cell division control protein 47); [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [PTHR11630:SF26] DNA REPLICATION LICENSING FACTOR MCM7 150.96 0.7278
191 Mapoly0010s0051 [PF12689] Acid Phosphatase; [GO:0016791] phosphatase activity; [PTHR17901] FAMILY NOT NAMED; [KOG4549] Magnesium-dependent phosphatase 150.96 0.6287
192 Mapoly0007s0227 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02212] minichromosome maintenance protein 4 (cell division control protein 54); [KOG0478] DNA replication licensing factor, MCM4 component; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 152.68 0.7290
193 Mapoly0029s0022 [PTHR23002] ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN; [PF06273] Plant specific eukaryotic initiation factor 4B; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding 152.73 0.6835
194 Mapoly0109s0054 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PF02229] Transcriptional Coactivator p15 (PC4); [KOG2712] Transcriptional coactivator; [PTHR13215] RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; [GO:0003713] transcription coactivator activity 153.28 0.7180
195 Mapoly0014s0217 [GO:0005515] protein binding; [KOG0322] G-protein beta subunit-like protein GNB1L, contains WD repeats; [PTHR19854:SF1] GB DEF: GUANINE NUCLEOTIDE-BINDING PROTEIN BETA SUBUNIT-LIKE PROTEIN 1 G PROTEIN BETA-S; [PTHR19854] TRANSDUCIN BETA-LIKE 3; [PF00400] WD domain, G-beta repeat 153.28 0.6671
196 Mapoly0024s0037 [K13151] snurportin-1; [KOG3132] m3G-cap-specific nuclear import receptor (Snurportin1); [PTHR13403:SF6] SNURPORTIN1 (RNUT1 PROTEIN) (RNA, U TRANSPORTER 1); [PTHR13403] SNURPORTIN1 (RNUT1 PROTEIN) (RNA, U TRANSPORTER 1) 154.37 0.6088
197 Mapoly0067s0089 [GO:0005515] protein binding; [PF00498] FHA domain; [PTHR23308] NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 154.48 0.7176
198 Mapoly0111s0057 [PF13865] C-terminal duplication domain of Friend of PRMT1 154.82 0.6845
199 Mapoly0030s0062 [PF04969] CS domain; [PTHR12356] NUCLEAR MOVEMENT PROTEIN NUDC; [KOG2265] Nuclear distribution protein NUDC 156.28 0.6487
200 Mapoly0012s0180 [PTHR15572] GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1; [PF15249] Glioma tumor suppressor candidate region 156.36 0.6895