Guide Gene
- Gene ID
- Mapoly0043s0128
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [KOG0381] HMG box-containing protein; [GO:0003677] DNA binding; [PF00505] HMG (high mobility group) box; [PF01388] ARID/BRIGHT DNA binding domain; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [GO:0005622] intracellular
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0043s0128 [KOG0381] HMG box-containing protein; [GO:0003677] DNA binding; [PF00505] HMG (high mobility group) box; [PF01388] ARID/BRIGHT DNA binding domain; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [GO:0005622] intracellular 0.00 1.0000 1 Mapoly0155s0001 [GO:0016597] amino acid binding; [PF01842] ACT domain; [GO:0008152] metabolic process; [PTHR31096] FAMILY NOT NAMED 1.00 0.8485 2 Mapoly0013s0011 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 3.46 0.8361 3 Mapoly0015s0045 [KOG0533] RRM motif-containing protein; [PTHR19965] RNA AND EXPORT FACTOR BINDING PROTEIN; [K12881] THO complex subunit 4; [PF13865] C-terminal duplication domain of Friend of PRMT1; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7.48 0.8062 4 Mapoly0152s0004 [PTHR12460] CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN; [PTHR12460:SF4] SUBFAMILY NOT NAMED; [PF04818] RNA polymerase II-binding domain.; [KOG2669] Regulator of nuclear mRNA 8.06 0.8147 5 Mapoly0029s0119 - 9.49 0.7784 6 Mapoly0052s0092 [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding; [KOG0106] Alternative splicing factor SRp55/B52/SRp75 (RRM superfamily); [PTHR10548] SPLICING FACTOR, ARGININE/SERINE-RICH; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 9.49 0.8046 7 Mapoly0105s0060 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [K12898] heterogeneous nuclear ribonucleoprotein F/H; [KOG4211] Splicing factor hnRNP-F and related RNA-binding proteins; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED 10.39 0.8210 8 Mapoly0001s0273 [PTHR10501] U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B; [PTHR10501:SF0] SMALL NUCLEAR RIBONUCLEOPROTEIN; [GO:0000398] mRNA splicing, via spliceosome; [GO:0003676] nucleic acid binding; [GO:0017069] snRNA binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 12.33 0.8058 9 Mapoly0005s0267 [PTHR23111] ZINC FINGER PROTEIN; [GO:0008270] zinc ion binding; [PF00641] Zn-finger in Ran binding protein and others 13.64 0.8115 10 Mapoly0037s0034 [K10744] ribonuclease H2 subunit B; [PTHR13383] FAMILY NOT NAMED; [PF09468] Ydr279p protein family (RNase H2 complex component); [GO:0005634] nucleus 13.86 0.8195 11 Mapoly0016s0080 [K14399] polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]; [PF03205] Molybdopterin guanine dinucleotide synthesis protein B; [KOG2749] mRNA cleavage and polyadenylation factor IA/II complex, subunit CLP1; [2.7.1.78] Polynucleotide 5'-hydroxyl-kinase.; [PTHR12755] CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P; [PF06807] Pre-mRNA cleavage complex II protein Clp1 15.30 0.7894 12 Mapoly0060s0105 [PTHR24012] FAMILY NOT NAMED; [KOG4207] Predicted splicing factor, SR protein superfamily; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 15.81 0.8033 13 Mapoly0014s0096 [GO:0005524] ATP binding; [K10755] replication factor C subunit 2/4; [KOG0989] Replication factor C, subunit RFC4; [PTHR11669] REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08542] Replication factor C C-terminal domain 15.97 0.7833 14 Mapoly0063s0059 [GO:0000812] Swr1 complex; [GO:0006338] chromatin remodeling; [GO:0006355] regulation of transcription, DNA-dependent; [GO:0031011] Ino80 complex; [PTHR11937:SF47] SUBFAMILY NOT NAMED; [GO:0035267] NuA4 histone acetyltransferase complex; [PF00022] Actin; [GO:0006281] DNA repair; [PTHR11937] ACTIN; [KOG0679] Actin-related protein - Arp4p/Act3p 17.15 0.7763 15 Mapoly0185s0017 [GO:0030915] Smc5-Smc6 complex; [PF08746] RING-like domain; [KOG4718] Non-SMC (structural maintenance of chromosomes) element 1 protein (NSE1); [PTHR20973] NON-SMC ELEMENT 1-RELATED; [PF07574] Nse1 non-SMC component of SMC5-6 complex; [GO:0006281] DNA repair; [PTHR20973:SF0] SUBFAMILY NOT NAMED 19.62 0.8027 16 Mapoly0214s0009 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 19.77 0.7745 17 Mapoly0014s0064 [PTHR10552] U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A; [K11092] U2 small nuclear ribonucleoprotein A'; [KOG1644] U2-associated snRNP A' protein; [PF14580] Leucine-rich repeat 23.66 0.7874 18 Mapoly0068s0031 [KOG1882] Transcriptional regulator SNIP1, contains FHA domain; [GO:0005515] protein binding; [K13108] smad nuclear-interacting protein 1; [PF00498] FHA domain; [PTHR23308] NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 23.92 0.7717 19 Mapoly0005s0155 [PF03517] Regulator of volume decrease after cellular swelling; [GO:0006821] chloride transport; [GO:0005829] cytosol; [GO:0005886] plasma membrane; [GO:0006884] cell volume homeostasis; [K05019] chloride channel, nucleotide-sensitive, 1A; [GO:0034709] methylosome; [GO:0034715] pICln-Sm protein complex; [KOG3238] Chloride ion current inducer protein; [PTHR21399] CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN; [GO:0000387] spliceosomal snRNP assembly 24.00 0.7726 20 Mapoly0050s0010 [KOG2829] E2F-like protein; [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [PTHR12548] TRANSCRIPTION FACTOR DP; [PF08781] Transcription factor DP; [GO:0007049] cell cycle 24.19 0.7023 21 Mapoly0007s0146 [KOG4374] RNA-binding protein Bicaudal-C; [PTHR15457] SEC-23 INTERACTING PROTEIN P125; [PF00536] SAM domain (Sterile alpha motif) 24.25 0.7483 22 Mapoly0053s0080 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PF12230] Pre-mRNA splicing factor PRP21 like protein; [GO:0005515] protein binding; [PTHR15316:SF1] SPLICEOSOME ASSOCIATED PROTEIN 114; [PF00240] Ubiquitin family; [K12825] splicing factor 3A subunit 1; [PTHR15316] SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED; [PF01805] Surp module; [KOG0007] Splicing factor 3a, subunit 1 24.66 0.7780 23 Mapoly0001s0015 [PTHR13555] C2H2 ZINC FINGER CGI-62-RELATED 25.30 0.7577 24 Mapoly0009s0067 [PTHR31789] FAMILY NOT NAMED 25.46 0.7710 25 Mapoly0034s0111 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 28.98 0.7902 26 Mapoly0007s0066 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PTHR19306:SF1] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5 SMC5; [KOG0979] Structural maintenance of chromosome protein SMC5/Spr18, SMC superfamily; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0000724] double-strand break repair via homologous recombination 29.66 0.7833 27 Mapoly0023s0117 [PTHR10139] DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11A; [PF04152] Mre11 DNA-binding presumed domain; [KOG2310] DNA repair exonuclease MRE11; [GO:0006259] DNA metabolic process; [PF00149] Calcineurin-like phosphoesterase; [GO:0006302] double-strand break repair; [GO:0016787] hydrolase activity; [GO:0030145] manganese ion binding; [GO:0005634] nucleus; [GO:0004527] exonuclease activity; [K10865] double-strand break repair protein MRE11; [GO:0004519] endonuclease activity 31.75 0.7700 28 Mapoly0007s0152 [PTHR23147] SERINE/ARGININE RICH SPLICING FACTOR; [KOG4207] Predicted splicing factor, SR protein superfamily; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 31.94 0.7666 29 Mapoly0080s0039 [PTHR15081] NUCLEAR AUTOANTIGENIC SPERM PROTEIN (NASP)-RELATED; [PF13414] TPR repeat; [PF10516] SHNi-TPR 33.50 0.7745 30 Mapoly0024s0018 [PTHR23147] SERINE/ARGININE RICH SPLICING FACTOR; [KOG4207] Predicted splicing factor, SR protein superfamily; [K12891] splicing factor, arginine/serine-rich 2; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 34.47 0.7621 31 Mapoly0105s0026 - 34.87 0.7583 32 Mapoly0069s0030 [PF03735] ENT domain; [KOG4675] Uncharacterized conserved protein, contains ENT domain 37.08 0.6995 33 Mapoly0154s0022 [GO:0003723] RNA binding; [GO:0016787] hydrolase activity; [PTHR23114] FAMILY NOT NAMED; [PF05026] Dcp2, box A domain; [GO:0030145] manganese ion binding; [PTHR23114:SF9] SUBFAMILY NOT NAMED; [3.-.-.-] Hydrolases.; [KOG2839] Diadenosine and diphosphoinositol polyphosphate phosphohydrolase; [PF00293] NUDIX domain; [K12613] mRNA-decapping enzyme subunit 2 [EC:3.-.-.-] 40.31 0.7351 34 Mapoly0053s0016 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 40.82 0.7803 35 Mapoly0070s0095 [PTHR23215] ZINC FINGER PROTEIN 207; [KOG2893] Zn finger protein 41.67 0.7657 36 Mapoly0013s0062 [GO:0003677] DNA binding; [PTHR15348:SF0] SUBFAMILY NOT NAMED; [PF01388] ARID/BRIGHT DNA binding domain; [GO:0005622] intracellular; [PTHR15348] AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN (ARID DOMAIN- CONTAINING PROTEIN) (DEAD RINGER PROTEIN) (B-CELL REGULATOR OF IGH TRANSCRIPTION) (BRIGHT) 42.72 0.7719 37 Mapoly0073s0079 [GO:0046907] intracellular transport; [GO:0005643] nuclear pore; [PTHR23138] RAN BINDING PROTEIN; [PTHR23138:SF46] ABR034WP; [PF00638] RanBP1 domain; [PF08911] NUP50 (Nucleoporin 50 kDa) 46.72 0.7600 38 Mapoly0118s0038 - 47.56 0.7579 39 Mapoly0011s0143 [PTHR15481:SF0] SUBFAMILY NOT NAMED; [K14325] RNA-binding protein with serine-rich domain 1; [PTHR15481] RIBONUCLEIC ACID BINDING PROTEIN S1; [GO:0003676] nucleic acid binding; [KOG0130] RNA-binding protein RBM8/Tsunagi (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 48.47 0.7686 40 Mapoly0089s0012 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 49.48 0.7463 41 Mapoly0007s0226 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 51.38 0.7633 42 Mapoly0042s0007 [GO:0003677] DNA binding; [K02213] cell division control protein 6; [KOG2227] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase; [PF13401] AAA domain; [PF01429] Methyl-CpG binding domain; [GO:0005634] nucleus; [PF09079] CDC6, C terminal; [PTHR10763] CELL DIVISION CONTROL PROTEIN 6-RELATED 52.65 0.7568 43 Mapoly0051s0023 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III 54.22 0.7775 44 Mapoly0012s0102 [PTHR23365] POLY-A BINDING PROTEIN 2; [K14396] polyadenylate-binding protein 2; [KOG4209] Splicing factor RNPS1, SR protein superfamily; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 55.56 0.7367 45 Mapoly0091s0013 [GO:0003723] RNA binding; [KOG2202] U2 snRNP splicing factor, small subunit, and related proteins; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PTHR12620] U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT; [GO:0005634] nucleus; [K12836] splicing factor U2AF 35 kDa subunit; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [GO:0046872] metal ion binding 57.13 0.7635 46 Mapoly0051s0085 [KOG2267] Eukaryotic-type DNA primase, large subunit; [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10537] DNA PRIMASE LARGE SUBUNIT; [K02685] DNA primase large subunit [EC:2.7.7.-]; [PF04104] Eukaryotic and archaeal DNA primase, large subunit; [2.7.7.-] Nucleotidyltransferases. 58.60 0.7627 47 Mapoly0112s0002 [PF14750] Integrator complex subunit 2; [K13139] integrator complex subunit 2; [GO:0032039] integrator complex 58.74 0.7252 48 Mapoly0040s0126 [K03131] transcription initiation factor TFIID subunit 6; [GO:0006352] DNA-dependent transcription, initiation; [PF07571] Protein of unknown function (DUF1546); [PF02969] TATA box binding protein associated factor (TAF); [GO:0005634] nucleus; [GO:0051090] regulation of sequence-specific DNA binding transcription factor activity; [KOG2549] Transcription initiation factor TFIID, subunit TAF6 (also component of histone acetyltransferase SAGA); [PTHR10221] TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 58.77 0.6286 49 Mapoly0046s0091 [GO:0000278] mitotic cell cycle; [PTHR22870] REGULATOR OF CHROMOSOME CONDENSATION; [KOG1427] Uncharacterized conserved protein, contains RCC1 domain; [PF00415] Regulator of chromosome condensation (RCC1) repeat; [GO:0051301] cell division; [GO:0007032] endosome organization 58.79 0.7493 50 Mapoly0001s0351 [KOG3404] G10 protein/predicted nuclear transcription regulator; [PTHR19411] G10 PROTEIN HOMOLOG; [PF01125] G10 protein; [GO:0005634] nucleus; [K12873] bud site selection protein 31 60.60 0.6614 51 Mapoly0010s0030 [PTHR22880] FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; [GO:0005515] protein binding; [PF00439] Bromodomain 61.87 0.7337 52 Mapoly0038s0101 [K12837] splicing factor U2AF 65 kDa subunit; [PTHR23139] RNA-BINDING PROTEIN; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG0120] Splicing factor U2AF, large subunit (RRM superfamily); [GO:0003676] nucleic acid binding; [PTHR23139:SF9] SPLICING FACTOR U2AF LARGE SUBUNIT; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 62.08 0.7569 53 Mapoly0001s0064 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [GO:0008173] RNA methyltransferase activity; [PTHR12029] RNA METHYLTRANSFERASE; [KOG0838] RNA Methylase, SpoU family; [PF00588] SpoU rRNA Methylase family 62.58 0.7540 54 Mapoly0106s0044 [PF03980] Nnf1 62.80 0.7030 55 Mapoly0052s0111 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG4206] Spliceosomal protein snRNP-U1A/U2B; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED 66.18 0.7410 56 Mapoly0101s0048 [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat 66.41 0.7624 57 Mapoly0001s0378 [PTHR32086] FAMILY NOT NAMED; [K10891] fanconi anemia group D2 protein; [GO:0006281] DNA repair; [KOG4712] Uncharacterized conserved protein; [PF14631] Fanconi anaemia protein FancD2 nuclease 67.14 0.7500 58 Mapoly0151s0042 [PTHR31500:SF0] SUBFAMILY NOT NAMED; [PF03479] Domain of unknown function (DUF296); [PTHR31500] FAMILY NOT NAMED 67.69 0.7240 59 Mapoly0147s0033 [PF07738] Sad1 / UNC-like C-terminal; [PTHR12911] SAD1/UNC-84-LIKE PROTEIN-RELATED; [KOG2687] Spindle pole body protein, contains UNC-84 domain 69.71 0.7447 60 Mapoly0096s0020 [GO:0005524] ATP binding; [PF02359] Cell division protein 48 (CDC48), N-terminal domain; [PF02933] Cell division protein 48 (CDC48), domain 2; [PF00004] ATPase family associated with various cellular activities (AAA); [K13525] transitional endoplasmic reticulum ATPase; [PTHR23077] AAA-FAMILY ATPASE; [KOG0730] AAA+-type ATPase 70.20 0.7430 61 Mapoly0014s0097 [PF13414] TPR repeat; [KOG1308] Hsp70-interacting protein Hip/Transient component of progesterone receptor complexes and an Hsp70-binding protein; [PTHR22904:SF34] HSC70-INTERACTING PROTEIN; [PTHR22904] TPR REPEAT CONTAINING PROTEIN 70.71 0.7464 62 Mapoly0157s0022 [PTHR13889:SF11] SUBFAMILY NOT NAMED; [K10599] pre-mRNA-processing factor 19 [EC:6.3.2.19]; [PF08606] Prp19/Pso4-like; [GO:0005515] protein binding; [KOG0289] mRNA splicing factor; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR13889] PRE-MRNA SPLICING FACTOR PRP19-RELATED; [PF00400] WD domain, G-beta repeat 70.88 0.6875 63 Mapoly0101s0017 [KOG1294] Apurinic/apyrimidinic endonuclease and related enzymes; [PTHR22748:SF1] AP ENDONUCLEASE; [GO:0006281] DNA repair; [PF03372] Endonuclease/Exonuclease/phosphatase family; [GO:0004518] nuclease activity; [PTHR22748] AP ENDONUCLEASE 73.76 0.7194 64 Mapoly0214s0010 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 76.34 0.7499 65 Mapoly0015s0164 [GO:0003677] DNA binding; [PF02362] B3 DNA binding domain; [PTHR31391] FAMILY NOT NAMED 77.55 0.7376 66 Mapoly0086s0078 [GO:0003677] DNA binding; [GO:0006275] regulation of DNA replication; [GO:0030337] DNA polymerase processivity factor activity; [PTHR11352] PROLIFERATING CELL NUCLEAR ANTIGEN; [PF00705] Proliferating cell nuclear antigen, N-terminal domain; [KOG1636] DNA polymerase delta processivity factor (proliferating cell nuclear antigen); [PF02747] Proliferating cell nuclear antigen, C-terminal domain 78.08 0.7337 67 Mapoly0028s0082 - 78.23 0.6775 68 Mapoly0051s0067 [PF00651] BTB/POZ domain; [PTHR24411] FAMILY NOT NAMED; [PF00917] MATH domain; [GO:0005515] protein binding; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 79.37 0.6954 69 Mapoly0016s0108 [GO:0005524] ATP binding; [K10755] replication factor C subunit 2/4; [KOG0991] Replication factor C, subunit RFC2; [PTHR11669] REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08542] Replication factor C C-terminal domain 79.67 0.7307 70 Mapoly0065s0033 [GO:0003723] RNA binding; [3.1.26.5] Ribonuclease P.; [K03538] ribonuclease P protein subunit POP4 [EC:3.1.26.5]; [GO:0000172] ribonuclease MRP complex; [PF01868] Domain of unknown function UPF0086; [PTHR13348] RIBONUCLEASE P; [GO:0006364] rRNA processing; [GO:0008033] tRNA processing; [GO:0030677] ribonuclease P complex; [GO:0006379] mRNA cleavage; [KOG4046] RNase MRP and P, subunit POP4/p29; [GO:0004540] ribonuclease activity 80.16 0.7013 71 Mapoly0027s0105 - 81.03 0.7142 72 Mapoly0005s0061 [PF00089] Trypsin; [PTHR22939] SERINE PROTEASE FAMILY S1C HTRA-RELATED; [GO:0005515] protein binding; [PF13180] PDZ domain; [KOG1320] Serine protease; [GO:0004252] serine-type endopeptidase activity; [GO:0006508] proteolysis 81.90 0.7242 73 Mapoly0109s0054 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PF02229] Transcriptional Coactivator p15 (PC4); [KOG2712] Transcriptional coactivator; [PTHR13215] RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; [GO:0003713] transcription coactivator activity 81.91 0.7430 74 Mapoly0079s0005 [GO:0008080] N-acetyltransferase activity; [GO:0016568] chromatin modification; [PF00583] Acetyltransferase (GNAT) family; [GO:0005634] nucleus; [GO:0004402] histone acetyltransferase activity; [GO:0016573] histone acetylation; [KOG2696] Histone acetyltransferase type b catalytic subunit; [GO:0006348] chromatin silencing at telomere; [2.3.1.48] Histone acetyltransferase.; [PTHR12046] HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT; [K11303] histone acetyltransferase 1 [EC:2.3.1.48]; [PF10394] Histone acetyl transferase HAT1 N-terminus 82.69 0.7450 75 Mapoly0019s0028 [PTHR24011] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [KOG0117] Heterogeneous nuclear ribonucleoprotein R (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 85.46 0.7204 76 Mapoly0166s0018 [K10739] replication factor A2; [KOG3108] Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit; [PF08784] Replication protein A C terminal; [PTHR13989] REPLICATION PROTEIN A-RELATED; [GO:0003676] nucleic acid binding; [PF01336] OB-fold nucleic acid binding domain 86.69 0.7519 77 Mapoly0075s0022 [KOG0482] DNA replication licensing factor, MCM7 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [K02210] minichromosome maintenance protein 7 (cell division control protein 47); [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [PTHR11630:SF26] DNA REPLICATION LICENSING FACTOR MCM7 86.75 0.7541 78 Mapoly0084s0054 [K03029] 26S proteasome regulatory subunit N10; [PF02809] Ubiquitin interaction motif; [PF13519] von Willebrand factor type A domain; [GO:0006511] ubiquitin-dependent protein catabolic process; [PTHR10223] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4; [GO:0008540] proteasome regulatory particle, base subcomplex; [KOG2884] 26S proteasome regulatory complex, subunit RPN10/PSMD4 88.59 0.7291 79 Mapoly0050s0101 [3.4.21.48] Cerevisin.; [K01336] cerevisin [EC:3.4.21.48]; [GO:0004252] serine-type endopeptidase activity; [PF00082] Subtilase family; [PF00090] Thrombospondin type 1 domain; [PF00053] Laminin EGF-like (Domains III and V); [GO:0006508] proteolysis; [PTHR10795] PROPROTEIN CONVERTASE SUBTILISIN/KEXIN 89.49 0.7125 80 Mapoly0029s0012 [GO:0005524] ATP binding; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [KOG0329] ATP-dependent RNA helicase; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding 89.78 0.7463 81 Mapoly0097s0033 [PTHR10870] CELL CYCLE CHECKPOINT PROTEIN RAD1; [KOG3194] Checkpoint 9-1-1 complex, RAD1 component; [PF02144] Repair protein Rad1/Rec1/Rad17; [GO:0005634] nucleus; [K02830] cell cycle checkpoint protein [EC:3.1.11.2]; [GO:0006281] DNA repair; [3.1.11.2] Exodeoxyribonuclease III. 94.68 0.6832 82 Mapoly0001s0348 [KOG1342] Histone deacetylase complex, catalytic component RPD3; [PF00850] Histone deacetylase domain; [PTHR10625] HISTONE DEACETYLASE 98.31 0.6889 83 Mapoly0029s0099 [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PTHR23336:SF7] SUBFAMILY NOT NAMED; [KOG1845] MORC family ATPases; [PTHR23336] ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3. 98.50 0.7141 84 Mapoly0044s0021 [KOG0275] Conserved WD40 repeat-containing protein; [PTHR22848] WD40 REPEAT PROTEIN; [GO:0005515] protein binding; [K13111] WD40 repeat-containing protein SMU1; [PF00400] WD domain, G-beta repeat 99.72 0.7177 85 Mapoly0087s0074 [GO:0005685] U1 snRNP; [PF06220] U1 zinc finger; [GO:0008270] zinc ion binding; [GO:0000398] mRNA splicing, via spliceosome; [KOG3454] U1 snRNP-specific protein C; [GO:0000387] spliceosomal snRNP assembly; [PTHR31148] FAMILY NOT NAMED 100.05 0.7299 86 Mapoly0010s0062 [KOG2250] Glutamate/leucine/phenylalanine/valine dehydrogenases; [GO:0055114] oxidation-reduction process; [PTHR11606] GLUTAMATE DEHYDROGENASE; [GO:0016491] oxidoreductase activity; [PF00208] Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; [K00262] glutamate dehydrogenase (NADP+) [EC:1.4.1.4]; [GO:0006520] cellular amino acid metabolic process; [PTHR11606:SF4] SUBFAMILY NOT NAMED; [1.4.1.4] Glutamate dehydrogenase (NADP(+)).; [PF02812] Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 100.43 0.7248 87 Mapoly0010s0132 [KOG4825] Component of synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine-binding glycoprotein (43kDa); [PF02151] UvrB/uvrC motif; [GO:0005515] protein binding; [PTHR13371] GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN; [PTHR13371:SF0] SUBFAMILY NOT NAMED 100.52 0.6616 88 Mapoly0007s0014 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02540] minichromosome maintenance protein 2; [PF12619] Mini-chromosome maintenance protein 2; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PTHR11630:SF44] DNA REPLICATION LICENSING FACTOR MCM2; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [KOG0477] DNA replication licensing factor, MCM2 component 103.31 0.7419 89 Mapoly0061s0010 [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10536] DNA PRIMASE SMALL SUBUNIT; [KOG2851] Eukaryotic-type DNA primase, catalytic (small) subunit; [K02684] DNA primase small subunit [EC:2.7.7.-]; [2.7.7.-] Nucleotidyltransferases.; [PF01896] Eukaryotic and archaeal DNA primase small subunit 103.61 0.7406 90 Mapoly0001s0197 [K10733] GINS complex subunit 2; [GO:0006260] DNA replication; [PF05916] GINS complex protein; [GO:0005634] nucleus; [KOG4071] Uncharacterized conserved protein; [PTHR12772] DNA REPLICATION COMPLEX GINS PROTEIN PSF2 104.18 0.6851 91 Mapoly0007s0080 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 104.31 0.7359 92 Mapoly0032s0081 [GO:0008641] small protein activating enzyme activity; [GO:0045116] protein neddylation; [GO:0005524] ATP binding; [PTHR10953:SF6] UBIQUITIN-ACTIVATING ENZYME E1C (NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT); [KOG2015] NEDD8-activating complex, catalytic component UBA3; [PF08825] E2 binding domain; [GO:0016881] acid-amino acid ligase activity; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [K10686] ubiquitin-activating enzyme E1 C [EC:6.3.2.19] 104.31 0.6965 93 Mapoly0003s0057 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination 104.34 0.7429 94 Mapoly0014s0068 - 104.47 0.6628 95 Mapoly0048s0012 [GO:0015035] protein disulfide oxidoreductase activity; [KOG1752] Glutaredoxin and related proteins; [PTHR10168] GLUTAREDOXIN; [GO:0045454] cell redox homeostasis; [PF00462] Glutaredoxin; [GO:0009055] electron carrier activity 104.56 0.6068 96 Mapoly0016s0006 [PTHR19923] WD40 REPEAT PROTEINPRL1/PRL2-RELATED; [PTHR19923:SF0] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [K12862] pleiotropic regulator 1; [KOG0285] Pleiotropic regulator 1; [PF00400] WD domain, G-beta repeat 105.07 0.7168 97 Mapoly0067s0005 [PTHR24012] FAMILY NOT NAMED; [PTHR24012:SF39] SUBFAMILY NOT NAMED; [KOG0147] Transcriptional coactivator CAPER (RRM superfamily); [GO:0003676] nucleic acid binding; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [K13091] RNA-binding protein 39; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 106.41 0.7251 98 Mapoly0052s0098 [PF05512] AWPM-19-like family 106.87 0.6517 99 Mapoly0187s0003 [PTHR22880] FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; [K06062] histone acetyltransferase [EC:2.3.1.48]; [GO:0005515] protein binding; [PF00439] Bromodomain; [GO:0008080] N-acetyltransferase activity; [PF00583] Acetyltransferase (GNAT) family; [2.3.1.48] Histone acetyltransferase. 106.95 0.7000 100 Mapoly0214s0011 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 107.06 0.7284 101 Mapoly0001s0028 [KOG1659] Class 2 transcription repressor NC2, alpha subunit (DRAP1); [GO:0005622] intracellular; [GO:0043565] sequence-specific DNA binding; [PTHR10252:SF5] DR1-ASSOCIATED COREPRESSOR; [PF00808] Histone-like transcription factor (CBF/NF-Y) and archaeal histone; [PTHR10252] HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED 107.10 0.6880 102 Mapoly0111s0003 - 108.89 0.7036 103 Mapoly0170s0033 [PTHR11669] REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; [KOG2035] Replication factor C, subunit RFC3; [PF13177] DNA polymerase III, delta subunit; [PTHR11669:SF1] DNA POLYMERASE III SUBUNIT GAMMA/TAU; [PF08542] Replication factor C C-terminal domain; [K10756] replication factor C subunit 3/5 110.84 0.6708 104 Mapoly0099s0053 [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 111.13 0.7154 105 Mapoly0158s0006 - 111.22 0.7173 106 Mapoly0001s0105 [K02541] minichromosome maintenance protein 3; [KOG0479] DNA replication licensing factor, MCM3 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11630:SF46] DNA REPLICATION LICENSING FACTOR MCM3; [PF00493] MCM2/3/5 family; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 113.41 0.7411 107 Mapoly0003s0009 [GO:0005515] protein binding; [PTHR18763] WD-REPEAT PROTEIN 18; [PF00400] WD domain, G-beta repeat 114.47 0.6878 108 Mapoly0043s0064 [PF10979] Protein of unknown function (DUF2786) 115.15 0.7314 109 Mapoly0010s0010 [GO:0005643] nuclear pore; [PF13874] Nucleoporin complex subunit 54; [PTHR13000] NUCLEOPORIN P54; [KOG3091] Nuclear pore complex, p54 component (sc Nup57) 115.32 0.7163 110 Mapoly0013s0016 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR31614] FAMILY NOT NAMED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08661] Replication factor A protein 3; [GO:0006310] DNA recombination 116.12 0.7180 111 Mapoly0133s0013 [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10615] HISTONE ACETYLTRANSFERASE; [PF00856] SET domain 116.76 0.7298 112 Mapoly0005s0196 [PTHR24011] FAMILY NOT NAMED; [PF04059] RNA recognition motif 2; [GO:0003676] nucleic acid binding; [KOG4660] Protein Mei2, essential for commitment to meiosis, and related proteins; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 116.91 0.7129 113 Mapoly0052s0123 [PTHR12616] VACUOLAR PROTEIN SORTING VPS41 119.67 0.6887 114 Mapoly0105s0042 [KOG2761] START domain-containing proteins involved in steroidogenesis/phosphatidylcholine transfer; [PTHR19308] PHOSPHATIDYLCHOLINE TRANSFER PROTEIN; [PF01852] START domain; [GO:0008289] lipid binding 120.95 0.5960 115 Mapoly0098s0043 [PF12717] non-SMC mitotic condensation complex subunit 1; [GO:0007076] mitotic chromosome condensation; [K11491] condensin-2 complex subunit D3; [PTHR14222:SF1] CONDENSIN; [PTHR14222] CONDENSIN 121.66 0.7259 116 Mapoly0107s0034 [3.5.1.98] Histone deacetylase.; [KOG1342] Histone deacetylase complex, catalytic component RPD3; [K06067] histone deacetylase 1/2 [EC:3.5.1.98]; [PF00850] Histone deacetylase domain; [PTHR10625] HISTONE DEACETYLASE 121.96 0.7054 117 Mapoly0049s0118 [PTHR32002] FAMILY NOT NAMED; [PF02042] RWP-RK domain 122.52 0.6875 118 Mapoly0007s0003 [GO:0005515] protein binding; [PTHR19918:SF8] gb def: Meiosis-specific APC/C activator protein AMA1 (Activator of meiotic APC/C protei; [KOG0305] Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits; [K03363] cell division cycle 20, cofactor of APC complex; [PTHR19918] CELL DIVISION CYCLE 20 (CDC20) (FIZZY)-RELATED; [PF00400] WD domain, G-beta repeat 124.10 0.7137 119 Mapoly0038s0027 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PTHR10629:SF11] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF12047] Cytosine specific DNA methyltransferase replication foci domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 124.80 0.7014 120 Mapoly0036s0142 [GO:0003677] DNA binding; [KOG1757] Histone 2A; [K11251] histone H2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 125.15 0.7209 121 Mapoly0053s0055 [KOG0871] Class 2 transcription repressor NC2, beta subunit (Dr1); [GO:0043565] sequence-specific DNA binding; [PF00808] Histone-like transcription factor (CBF/NF-Y) and archaeal histone; [PTHR11064] CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED; [GO:0005622] intracellular 125.28 0.6607 122 Mapoly0003s0120 [GO:0003677] DNA binding; [PTHR12708:SF0] SUBFAMILY NOT NAMED; [GO:0006260] DNA replication; [PF12213] DNA polymerases epsilon N terminal; [2.7.7.7] DNA-directed DNA polymerase.; [PTHR12708] DNA POLYMERASE EPSILON SUBUNIT B; [KOG3818] DNA polymerase epsilon, subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [GO:0003887] DNA-directed DNA polymerase activity; [K02325] DNA polymerase epsilon subunit 2 [EC:2.7.7.7] 125.42 0.7089 123 Mapoly0108s0031 [GO:0005524] ATP binding; [K04499] RuvB-like protein 1 (pontin 52); [KOG1942] DNA helicase, TBP-interacting protein; [PF06068] TIP49 C-terminus; [GO:0043141] ATP-dependent 5'-3' DNA helicase activity; [GO:0003678] DNA helicase activity; [PTHR11093] RUVB-RELATED REPTIN AND PONTIN 125.92 0.7110 124 Mapoly0001s0501 [PF12681] Glyoxalase-like domain 126.75 0.6971 125 Mapoly0011s0104 [GO:0003755] peptidyl-prolyl cis-trans isomerase activity; [PTHR11071] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF00160] Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; [GO:0000413] protein peptidyl-prolyl isomerization; [KOG0546] HSP90 co-chaperone CPR7/Cyclophilin; [GO:0006457] protein folding 128.99 0.6793 126 Mapoly0029s0079 [GO:0042393] histone binding; [PF12165] Domain of unknown function (DUF3594); [GO:0006355] regulation of transcription, DNA-dependent; [KOG1632] Uncharacterized PHD Zn-finger protein; [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR12321] CPG BINDING PROTEIN 129.49 0.6985 127 Mapoly0060s0056 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 129.87 0.7129 128 Mapoly0120s0004 [PF00488] MutS domain V; [GO:0005524] ATP binding; [K08735] DNA mismatch repair protein MSH2; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PTHR11361:SF35] MUTS HOMOLOG 2, MSH2; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III; [KOG0219] Mismatch repair ATPase MSH2 (MutS family); [PF05190] MutS family domain IV 129.98 0.7148 129 Mapoly0004s0039 [KOG1656] Protein involved in glucose derepression and pre-vacuolar endosome protein sorting; [PF03357] Snf7; [GO:0015031] protein transport; [PTHR22761] SNF7 - RELATED 131.53 0.6598 130 Mapoly0112s0022 [PTHR19932] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; [GO:0005515] protein binding; [KOG1274] WD40 repeat protein; [K11274] chromosome transmission fidelity protein 4; [PTHR19932:SF10] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN 1; [PF00400] WD domain, G-beta repeat; [PF12341] Protein of unknown function (DUF3639) 134.71 0.7193 131 Mapoly0004s0008 - 137.72 0.6807 132 Mapoly0001s0457 [PTHR14360:SF1] UNCHARACTERIZED; [PF07798] Protein of unknown function (DUF1640); [KOG3156] Uncharacterized membrane protein; [PTHR14360] UNCHARACTERIZED 137.88 0.6708 133 Mapoly0103s0079 [GO:0003677] DNA binding; [PTHR13763:SF0] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0005634] nucleus; [GO:0006281] DNA repair; [GO:0004842] ubiquitin-protein ligase activity; [KOG4362] Transcriptional regulator BRCA1; [PTHR13763] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; [PF13771] PHD-like zinc-binding domain 138.85 0.7217 134 Mapoly0004s0118 [KOG0121] Nuclear cap-binding protein complex, subunit CBP20 (RRM superfamily); [PTHR15241] TRANSFORMER-2-RELATED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 140.29 0.6501 135 Mapoly0122s0062 [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 141.03 0.7171 136 Mapoly0029s0022 [PTHR23002] ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN; [PF06273] Plant specific eukaryotic initiation factor 4B; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding 141.05 0.6808 137 Mapoly0007s0227 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02212] minichromosome maintenance protein 4 (cell division control protein 54); [KOG0478] DNA replication licensing factor, MCM4 component; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 142.87 0.7198 138 Mapoly0013s0048 [KOG0381] HMG box-containing protein; [PF00505] HMG (high mobility group) box; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN 144.56 0.7210 139 Mapoly0084s0055 [GO:0005524] ATP binding; [KOG0744] AAA+-type ATPase; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23077] AAA-FAMILY ATPASE 144.67 0.6980 140 Mapoly0030s0020 [KOG2545] Conserved membrane protein; [PTHR13489:SF0] SUBFAMILY NOT NAMED; [PF13615] Putative alanine racemase; [PF09739] Mini-chromosome maintenance replisome factor; [PTHR13489] UNCHARACTERIZED 145.43 0.7160 141 Mapoly0006s0287 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02209] minichromosome maintenance protein 5 (cell division control protein 46); [PTHR11630:SF42] DNA REPLICATION LICENSING FACTOR MCM5; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain; [KOG0481] DNA replication licensing factor, MCM5 component 146.86 0.7170 142 Mapoly0213s0004 [PTHR24012] FAMILY NOT NAMED; [KOG0226] RNA-binding proteins; [GO:0003676] nucleic acid binding; [PTHR24012:SF41] SUBFAMILY NOT NAMED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 147.07 0.6586 143 Mapoly0070s0034 [KOG0108] mRNA cleavage and polyadenylation factor I complex, subunit RNA15; [PF14327] Hinge domain of cleavage stimulation factor subunit 2; [PTHR23139:SF8] RNA RECOGNITION MOTIF CONTAINING PROTEIN; [PTHR23139] RNA-BINDING PROTEIN; [GO:0003676] nucleic acid binding; [K14407] cleavage stimulation factor subunit 2; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 147.36 0.6949 144 Mapoly0146s0045 [GO:0003723] RNA binding; [PTHR11207:SF1] RIBONUCLEASE III; [PF00035] Double-stranded RNA binding motif; [GO:0004525] ribonuclease III activity; [GO:0016075] rRNA catabolic process; [PTHR11207] RIBONUCLEASE III 149.85 0.7080 145 Mapoly0014s0217 [GO:0005515] protein binding; [KOG0322] G-protein beta subunit-like protein GNB1L, contains WD repeats; [PTHR19854:SF1] GB DEF: GUANINE NUCLEOTIDE-BINDING PROTEIN BETA SUBUNIT-LIKE PROTEIN 1 G PROTEIN BETA-S; [PTHR19854] TRANSDUCIN BETA-LIKE 3; [PF00400] WD domain, G-beta repeat 151.26 0.6596 146 Mapoly0052s0086 [PF05641] Agenet domain; [PTHR31917] FAMILY NOT NAMED 151.66 0.7099 147 Mapoly0089s0046 [K06688] ubiquitin-conjugating enzyme E2 C [EC:6.3.2.19]; [PTHR24067:SF44] UBIQUITIN-CONJUGATING ENZYME E2 C; [PTHR24067] UBIQUITIN-CONJUGATING ENZYME E2; [GO:0016881] acid-amino acid ligase activity; [6.3.2.19] Ubiquitin--protein ligase.; [PF00179] Ubiquitin-conjugating enzyme; [KOG0421] Ubiquitin-protein ligase 152.50 0.6888 148 Mapoly0140s0032 [PTHR12748] ORIGIN RECOGNITION COMPLEX SUBUNIT 3; [PTHR12748:SF0] SUBFAMILY NOT NAMED; [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02605] origin recognition complex subunit 3; [PF07034] Origin recognition complex (ORC) subunit 3 N-terminus; [KOG2538] Origin recognition complex, subunit 3; [GO:0005664] nuclear origin of replication recognition complex; [PF02178] AT hook motif 152.90 0.7145 149 Mapoly0031s0081 [PF03151] Triose-phosphate Transporter family; [PTHR11132] SOLUTE CARRIER FAMILY 35; [KOG1441] Glucose-6-phosphate/phosphate and phosphoenolpyruvate/phosphate antiporter 154.55 0.6377 150 Mapoly0118s0024 [PTHR22840] FAMILY NOT NAMED; [GO:0005515] protein binding; [K14406] cleavage stimulation factor subunit 1; [KOG0640] mRNA cleavage stimulating factor complex; subunit 1; [PF00400] WD domain, G-beta repeat 154.96 0.6390 151 Mapoly0074s0043 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [GO:0003729] mRNA binding 155.31 0.7011 152 Mapoly0172s0017 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 156.32 0.6895 153 Mapoly0024s0114 [GO:0055114] oxidation-reduction process; [PTHR31155] ACYL-(ACYL-CARRIER-PROTEIN) DESATURASE-RELATED; [GO:0006631] fatty acid metabolic process; [PF03405] Fatty acid desaturase; [GO:0045300] acyl-[acyl-carrier-protein] desaturase activity 156.37 0.5925 154 Mapoly0064s0110 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR13394] ORIGIN RECOGNITION COMPLEX SUBUNIT 6; [PF05460] Origin recognition complex subunit 6 (ORC6); [GO:0005664] nuclear origin of replication recognition complex; [K02608] origin recognition complex subunit 6; [PTHR13394:SF0] SUBFAMILY NOT NAMED; [KOG4557] Origin recognition complex, subunit 6 157.55 0.7128 155 Mapoly0102s0037 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 158.09 0.6947 156 Mapoly0109s0026 [GO:0005515] protein binding; [KOG1446] Histone H3 (Lys4) methyltransferase complex and RNA cleavage factor II complex, subunit SWD2; [PTHR19861] WD40 REPEAT PROTEIN SWD2; [PF00400] WD domain, G-beta repeat 158.39 0.6460 157 Mapoly0050s0017 [PTHR31587] FAMILY NOT NAMED; [PF10225] Uncharacterized conserved protein (DUF2215) 158.66 0.5989 158 Mapoly0189s0011 [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain 159.68 0.7004 159 Mapoly0116s0028 [PTHR23074:SF19] KATANIN-RELATED; [GO:0005524] ATP binding; [3.6.4.3] Microtubule-severing ATPase.; [K07767] microtubule-severing ATPase [EC:3.6.4.3]; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0738] AAA+-type ATPase; [PTHR23074] AAA ATPASE; [PF09336] Vps4 C terminal oligomerisation domain 161.11 0.6783 160 Mapoly0001s0266 [GO:0003677] DNA binding; [PF01192] RNA polymerase Rpb6; [KOG3405] RNA polymerase subunit K; [PTHR10773] DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2; [GO:0006351] transcription, DNA-dependent; [GO:0003899] DNA-directed RNA polymerase activity; [K03014] DNA-directed RNA polymerases I, II, and III subunit RPABC2 161.35 0.6988 161 Mapoly0036s0154 [KOG2606] OTU (ovarian tumor)-like cysteine protease; [PTHR12419] OTU DOMAIN CONTAINING PROTEIN; [PTHR12419:SF10] gb def: ENSANGP00000019868 (Fragment); [PF02338] OTU-like cysteine protease 162.41 0.7010 162 Mapoly0081s0071 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [PF00628] PHD-finger; [GO:0005515] protein binding; [PF12738] twin BRCT domain; [GO:0046872] metal ion binding 163.28 0.6997 163 Mapoly0059s0079 [KOG2014] SMT3/SUMO-activating complex, AOS1/RAD31 component; [PF00899] ThiF family; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [K10684] ubiquitin-like 1-activating enzyme E1 A [EC:6.3.2.19] 163.33 0.7084 164 Mapoly0035s0108 [GO:0005524] ATP binding; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23074] AAA ATPASE; [KOG0740] AAA+-type ATPase; [PF09336] Vps4 C terminal oligomerisation domain; [PTHR23074:SF17] FIDGETIN LIKE-1 163.78 0.6918 165 Mapoly0087s0021 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [KOG0969] DNA polymerase delta, catalytic subunit; [PTHR10322:SF11] DNA POLYMERASE DELTA CATALYTIC SUBUNIT; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [K02327] DNA polymerase delta subunit 1 [EC:2.7.7.7]; [PF14260] C4-type zinc-finger of DNA polymerase delta; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT 164.49 0.6846 166 Mapoly0159s0020 [K05544] tRNA-dihydrouridine synthase 3 [EC:1.-.-.-]; [GO:0050660] flavin adenine dinucleotide binding; [GO:0055114] oxidation-reduction process; [PTHR11082:SF8] TRNA-DIHYDROURIDINE SYNTHASE 3; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PF01207] Dihydrouridine synthase (Dus); [KOG2333] Uncharacterized conserved protein; [GO:0008033] tRNA processing; [PTHR11082] TRNA-DIHYDROURIDINE SYNTHASE; [GO:0046872] metal ion binding; [GO:0017150] tRNA dihydrouridine synthase activity; [1.-.-.-] Oxidoreductases. 164.54 0.6741 167 Mapoly0055s0064 - 164.83 0.7059 168 Mapoly0024s0061 [KOG1508] DNA replication factor/protein phosphatase inhibitor SET/SPR-2; [PF00956] Nucleosome assembly protein (NAP); [GO:0005634] nucleus; [GO:0006334] nucleosome assembly; [K11290] template-activating factor I; [PTHR11875] TESTIS-SPECIFIC Y-ENCODED PROTEIN 164.97 0.6992 169 Mapoly0179s0001 [PTHR10994] RETICULON; [PF02453] Reticulon; [KOG1792] Reticulon 165.37 0.7039 170 Mapoly0004s0128 [GO:0005524] ATP binding; [K08864] tousled-like kinase [EC:2.7.11.1]; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PTHR22974] MIXED LINEAGE PROTEIN KINASE; [KOG1151] Tousled-like protein kinase 165.47 0.6895 171 Mapoly0021s0138 [KOG1548] Transcription elongation factor TAT-SF1; [GO:0005515] protein binding; [K13093] HIV Tat-specific factor 1; [PF02213] GYF domain; [PTHR15608] SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2; [PF14237] Domain of unknown function (DUF4339); [GO:0003676] nucleic acid binding; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 165.95 0.6818 172 Mapoly0064s0049 [PTHR19321:SF5] PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED; [GO:0000226] microtubule cytoskeleton organization; [GO:0000910] cytokinesis; [GO:0008017] microtubule binding; [PF03999] Microtubule associated protein (MAP65/ASE1 family); [KOG4302] Microtubule-associated protein essential for anaphase spindle elongation; [PTHR19321] PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED 166.97 0.6660 173 Mapoly0098s0009 [K01104] protein-tyrosine phosphatase [EC:3.1.3.48]; [PF00581] Rhodanese-like domain; [PTHR10828:SF17] M-PHASE INDUCER PHOSPHATASE (DUAL SPECIFICITY PHOSPHATASE CDC25); [PTHR10828] M-PHASE INDUCER PHOSPHATASE (DUAL SPECIFICITY PHOSPHATASE CDC25); [3.1.3.48] Protein-tyrosine-phosphatase. 167.59 0.6960 174 Mapoly0066s0041 [GO:0030915] Smc5-Smc6 complex; [PTHR21330] UNCHARACTERIZED; [GO:0019789] SUMO ligase activity; [PF11789] Zinc-finger of the MIZ type in Nse subunit; [GO:0000724] double-strand break repair via homologous recombination 168.69 0.6755 175 Mapoly0032s0110 [PTHR16219] FAMILY NOT NAMED; [PF14735] HAUS augmin-like complex subunit 4; [GO:0051225] spindle assembly; [GO:0070652] HAUS complex; [PTHR16219:SF1] SUBFAMILY NOT NAMED 169.38 0.6314 176 Mapoly0135s0035 [GO:0003676] nucleic acid binding; [PF02037] SAP domain 170.11 0.6864 177 Mapoly0019s0059 [PTHR31398:SF0] SUBFAMILY NOT NAMED; [PTHR31398] FAMILY NOT NAMED; [PF03962] Mnd1 family; [KOG3433] Protein involved in meiotic recombination/predicted coiled-coil protein 174.62 0.6977 178 Mapoly0153s0029 [KOG2551] Phospholipase/carboxyhydrolase; [PF03959] Serine hydrolase (FSH1); [PTHR22778] OVARIAN CANCER GENE-2 PROTEIN-RELATED; [PTHR22778:SF0] SUBFAMILY NOT NAMED 176.10 0.5884 179 Mapoly0158s0032 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [K10728] topoisomerase (DNA) II binding protein 1; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 176.59 0.6735 180 Mapoly0027s0185 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF39] CDC2-RELATED PROTEIN KINASE; [KOG0600] Cdc2-related protein kinase; [K08819] Cdc2-related kinase, arginine/serine-rich [EC:2.7.11.22]; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 177.99 0.6859 181 Mapoly0035s0099 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02321] DNA polymerase alpha subunit B; [PTHR23061:SF12] SUBFAMILY NOT NAMED; [KOG1625] DNA polymerase alpha-primase complex, polymerase-associated subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [PTHR23061] DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; [GO:0003887] DNA-directed DNA polymerase activity; [PF08418] DNA polymerase alpha subunit B N-terminal 178.50 0.6983 182 Mapoly0111s0057 [PF13865] C-terminal duplication domain of Friend of PRMT1 178.66 0.6646 183 Mapoly0011s0202 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain 179.29 0.7044 184 Mapoly0169s0015 [GO:0006355] regulation of transcription, DNA-dependent; [KOG3149] Transcription initiation factor IIF, auxiliary subunit; [PTHR23195] YEATS DOMAIN; [PF03366] YEATS family; [GO:0005634] nucleus; [K11341] YEATS domain-containing protein 4 180.98 0.6658 185 Mapoly0014s0204 [PTHR24012] FAMILY NOT NAMED; [PTHR24012:SF31] SUBFAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 181.75 0.6679 186 Mapoly0009s0203 - 183.00 0.6647 187 Mapoly0005s0138 - 183.30 0.6804 188 Mapoly0029s0121 [K11550] kinetochore protein Spc25, animal type; [PF08234] Chromosome segregation protein Spc25; [PTHR14281] FAMILY NOT NAMED 185.29 0.6956 189 Mapoly0005s0205 [PF00226] DnaJ domain; [KOG0719] Molecular chaperone (DnaJ superfamily); [PTHR24078] DNAJ HOMOLOG SUBFAMILY C MEMBER 186.67 0.7033 190 Mapoly0038s0109 [PTHR11842] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2; [GO:0007094] mitotic spindle assembly checkpoint; [PF02301] HORMA domain; [K02537] mitotic spindle assembly checkpoint protein MAD2; [PTHR11842:SF11] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A; [KOG3285] Spindle assembly checkpoint protein 186.90 0.6713 191 Mapoly0103s0016 [K10840] centrin-2; [KOG0028] Ca2+-binding protein (centrin/caltractin), EF-Hand superfamily protein; [PTHR23050] CALCIUM BINDING PROTEIN; [PF13499] EF-hand domain pair; [PF13833] EF-hand domain pair; [GO:0005509] calcium ion binding 187.16 0.6582 192 Mapoly0013s0183 [KOG2739] Leucine-rich acidic nuclear protein; [PF14580] Leucine-rich repeat; [PTHR11375] ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 187.40 0.6663 193 Mapoly0030s0102 [PF08317] Spc7 kinetochore protein 188.09 0.6975 194 Mapoly0055s0120 - 188.60 0.6825 195 Mapoly0005s0256 [PF12220] U1 small nuclear ribonucleoprotein of 70kDa MW N terminal; [KOG0113] U1 small nuclear ribonucleoprotein (RRM superfamily); [PTHR13952:SF5] PREDICTED: HYPOTHETICAL PROTEIN, PARTIAL; [PTHR13952] U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD; [K11093] U1 small nuclear ribonucleoprotein 70kDa; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 188.98 0.6714 196 Mapoly0095s0052 [PF08839] DNA replication factor CDT1 like 190.33 0.6854 197 Mapoly0029s0045 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0243] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [PF12711] Kinesin motor; [GO:0003777] microtubule motor activity; [K10400] kinesin family member 15 190.82 0.6533 198 Mapoly0104s0010 [PTHR17204:SF5] PRE-MRNA PROCESSING PROTEIN PRP39-RELATED; [K13217] pre-mRNA-processing factor 39; [KOG1258] mRNA processing protein; [GO:0006397] mRNA processing; [GO:0005634] nucleus; [PF05843] Suppressor of forked protein (Suf); [PTHR17204] PRE-MRNA PROCESSING PROTEIN PRP39-RELATED 190.87 0.6764 199 Mapoly0113s0048 [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [KOG1408] WD40 repeat protein; [PF00400] WD domain, G-beta repeat 190.91 0.6975 200 Mapoly0054s0111 [KOG3371] Uncharacterized conserved protein; [PTHR15854] THAP4 PROTEIN; [PF08768] Domain of unknown function (DUF1794) 192.61 0.6142