Guide Gene
- Gene ID
- Mapoly0042s0007
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [GO:0003677] DNA binding; [K02213] cell division control protein 6; [KOG2227] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase; [PF13401] AAA domain; [PF01429] Methyl-CpG binding domain; [GO:0005634] nucleus; [PF09079] CDC6, C terminal; [PTHR10763] CELL DIVISION CONTROL PROTEIN 6-RELATED
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0042s0007 [GO:0003677] DNA binding; [K02213] cell division control protein 6; [KOG2227] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase; [PF13401] AAA domain; [PF01429] Methyl-CpG binding domain; [GO:0005634] nucleus; [PF09079] CDC6, C terminal; [PTHR10763] CELL DIVISION CONTROL PROTEIN 6-RELATED 0.00 1.0000 1 Mapoly0046s0091 [GO:0000278] mitotic cell cycle; [PTHR22870] REGULATOR OF CHROMOSOME CONDENSATION; [KOG1427] Uncharacterized conserved protein, contains RCC1 domain; [PF00415] Regulator of chromosome condensation (RCC1) repeat; [GO:0051301] cell division; [GO:0007032] endosome organization 1.00 0.8948 2 Mapoly0013s0048 [KOG0381] HMG box-containing protein; [PF00505] HMG (high mobility group) box; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN 4.00 0.8764 3 Mapoly0010s0062 [KOG2250] Glutamate/leucine/phenylalanine/valine dehydrogenases; [GO:0055114] oxidation-reduction process; [PTHR11606] GLUTAMATE DEHYDROGENASE; [GO:0016491] oxidoreductase activity; [PF00208] Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; [K00262] glutamate dehydrogenase (NADP+) [EC:1.4.1.4]; [GO:0006520] cellular amino acid metabolic process; [PTHR11606:SF4] SUBFAMILY NOT NAMED; [1.4.1.4] Glutamate dehydrogenase (NADP(+)).; [PF02812] Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 4.90 0.8625 4 Mapoly0152s0004 [PTHR12460] CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN; [PTHR12460:SF4] SUBFAMILY NOT NAMED; [PF04818] RNA polymerase II-binding domain.; [KOG2669] Regulator of nuclear mRNA 5.66 0.8383 5 Mapoly0023s0050 [PF11559] Afadin- and alpha -actinin-Binding; [PTHR21736] VERNALIZATION-INSENSITIVE PROTEIN 3 8.49 0.8359 6 Mapoly0053s0016 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 10.00 0.8530 7 Mapoly0034s0111 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 10.39 0.8517 8 Mapoly0052s0086 [PF05641] Agenet domain; [PTHR31917] FAMILY NOT NAMED 11.22 0.8387 9 Mapoly0051s0092 [GO:0007264] small GTPase mediated signal transduction; [K07975] Rho family, other; [PTHR24072] RHO FAMILY GTPASE; [KOG0393] Ras-related small GTPase, Rho type; [PF00071] Ras family; [GO:0005525] GTP binding 12.33 0.7931 10 Mapoly0011s0083 [PTHR10997] IMPORTIN-7, 8, 11 12.96 0.8265 11 Mapoly0006s0287 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02209] minichromosome maintenance protein 5 (cell division control protein 46); [PTHR11630:SF42] DNA REPLICATION LICENSING FACTOR MCM5; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain; [KOG0481] DNA replication licensing factor, MCM5 component 15.00 0.8529 12 Mapoly0036s0142 [GO:0003677] DNA binding; [KOG1757] Histone 2A; [K11251] histone H2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 18.00 0.8269 13 Mapoly0022s0115 [GO:0006284] base-excision repair; [PF03352] Methyladenine glycosylase; [GO:0008725] DNA-3-methyladenine glycosylase activity; [3.2.2.20] DNA-3-methyladenine glycosylase I.; [K01246] DNA-3-methyladenine glycosylase I [EC:3.2.2.20]; [PTHR31116] FAMILY NOT NAMED 18.97 0.7904 14 Mapoly0124s0012 [KOG2518] 5'-3' exonuclease; [PF00752] XPG N-terminal domain; [PF00867] XPG I-region; [K10746] exonuclease 1 [EC:3.1.-.-]; [GO:0006281] DNA repair; [GO:0004518] nuclease activity; [PTHR11081:SF8] EXONUCLEASE 1; [3.1.-.-] Acting on ester bonds.; [PTHR11081] XP-G/RAD2 DNA REPAIR ENDONUCLEASE FAMILY 19.44 0.7280 15 Mapoly0001s0010 [PTHR22926] PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE; [PF10555] Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1; [GO:0016021] integral to membrane; [PF00953] Glycosyl transferase family 4; [GO:0008963] phospho-N-acetylmuramoyl-pentapeptide-transferase activity 20.88 0.7363 16 Mapoly0001s0378 [PTHR32086] FAMILY NOT NAMED; [K10891] fanconi anemia group D2 protein; [GO:0006281] DNA repair; [KOG4712] Uncharacterized conserved protein; [PF14631] Fanconi anaemia protein FancD2 nuclease 21.98 0.8050 17 Mapoly0005s0267 [PTHR23111] ZINC FINGER PROTEIN; [GO:0008270] zinc ion binding; [PF00641] Zn-finger in Ran binding protein and others 22.85 0.8150 18 Mapoly0009s0136 [PTHR24012] FAMILY NOT NAMED; [KOG0126] Predicted RNA-binding protein (RRM superfamily); [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 22.91 0.7945 19 Mapoly0029s0119 - 24.66 0.7526 20 Mapoly0075s0022 [KOG0482] DNA replication licensing factor, MCM7 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [K02210] minichromosome maintenance protein 7 (cell division control protein 47); [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [PTHR11630:SF26] DNA REPLICATION LICENSING FACTOR MCM7 24.70 0.8354 21 Mapoly0005s0205 [PF00226] DnaJ domain; [KOG0719] Molecular chaperone (DnaJ superfamily); [PTHR24078] DNAJ HOMOLOG SUBFAMILY C MEMBER 25.30 0.8212 22 Mapoly0060s0047 [GO:0003723] RNA binding; [PTHR10288] KH DOMAIN CONTAINING RNA BINDING PROTEIN; [PF00013] KH domain; [KOG2191] RNA-binding protein NOVA1/PASILLA and related KH domain proteins 25.50 0.7572 23 Mapoly0024s0114 [GO:0055114] oxidation-reduction process; [PTHR31155] ACYL-(ACYL-CARRIER-PROTEIN) DESATURASE-RELATED; [GO:0006631] fatty acid metabolic process; [PF03405] Fatty acid desaturase; [GO:0045300] acyl-[acyl-carrier-protein] desaturase activity 26.46 0.7017 24 Mapoly0185s0017 [GO:0030915] Smc5-Smc6 complex; [PF08746] RING-like domain; [KOG4718] Non-SMC (structural maintenance of chromosomes) element 1 protein (NSE1); [PTHR20973] NON-SMC ELEMENT 1-RELATED; [PF07574] Nse1 non-SMC component of SMC5-6 complex; [GO:0006281] DNA repair; [PTHR20973:SF0] SUBFAMILY NOT NAMED 26.94 0.8036 25 Mapoly0119s0016 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [KOG0480] DNA replication licensing factor, MCM6 component; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630:SF43] DNA REPLICATION LICENSING FACTOR MCM6; [K02542] minichromosome maintenance protein 6; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain 28.91 0.8289 26 Mapoly0060s0056 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 29.39 0.7959 27 Mapoly0007s0080 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 29.50 0.8252 28 Mapoly0003s0088 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 29.73 0.8164 29 Mapoly0133s0010 [PF00692] dUTPase; [GO:0046080] dUTP metabolic process; [3.6.1.23] dUTP diphosphatase.; [GO:0016787] hydrolase activity; [PTHR11241] DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE; [K01520] dUTP pyrophosphatase [EC:3.6.1.23]; [KOG3370] dUTPase 30.00 0.8099 30 Mapoly0011s0137 [K03504] DNA polymerase delta subunit 3; [GO:0006260] DNA replication; [PTHR17598] FAMILY NOT NAMED; [PF09507] DNA polymerase subunit Cdc27; [GO:0005634] nucleus 30.94 0.7967 31 Mapoly0035s0108 [GO:0005524] ATP binding; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23074] AAA ATPASE; [KOG0740] AAA+-type ATPase; [PF09336] Vps4 C terminal oligomerisation domain; [PTHR23074:SF17] FIDGETIN LIKE-1 31.45 0.7867 32 Mapoly0037s0034 [K10744] ribonuclease H2 subunit B; [PTHR13383] FAMILY NOT NAMED; [PF09468] Ydr279p protein family (RNase H2 complex component); [GO:0005634] nucleus 32.03 0.8148 33 Mapoly0007s0227 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02212] minichromosome maintenance protein 4 (cell division control protein 54); [KOG0478] DNA replication licensing factor, MCM4 component; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 32.05 0.8268 34 Mapoly0066s0004 [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [KOG0496] Beta-galactosidase; [GO:0005975] carbohydrate metabolic process; [PF02140] Galactose binding lectin domain; [GO:0030246] carbohydrate binding; [PTHR23421] BETA-GALACTOSIDASE RELATED; [PF01301] Glycosyl hydrolases family 35 32.83 0.7525 35 Mapoly0172s0017 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 33.23 0.8017 36 Mapoly0067s0068 [KOG2266] Chromatin-associated protein Dek and related proteins, contains SAP DNA binding domain; [PTHR13468:SF1] DEK ONCOGENE; [PF08766] DEK C terminal domain; [PTHR13468] DEK PROTEIN 34.58 0.7988 37 Mapoly0045s0075 - 35.50 0.7482 38 Mapoly0112s0002 [PF14750] Integrator complex subunit 2; [K13139] integrator complex subunit 2; [GO:0032039] integrator complex 36.65 0.7505 39 Mapoly0095s0052 [PF08839] DNA replication factor CDT1 like 37.55 0.7960 40 Mapoly0115s0027 [PTHR31084:SF0] SUBFAMILY NOT NAMED; [PF14498] Glycosyl hydrolase family 65, N-terminal domain; [PTHR31084] FAMILY NOT NAMED 40.36 0.6982 41 Mapoly0080s0039 [PTHR15081] NUCLEAR AUTOANTIGENIC SPERM PROTEIN (NASP)-RELATED; [PF13414] TPR repeat; [PF10516] SHNi-TPR 41.35 0.7834 42 Mapoly0007s0226 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 42.58 0.7932 43 Mapoly0002s0042 [GO:0031011] Ino80 complex; [PTHR13052:SF0] SUBFAMILY NOT NAMED; [PTHR13052] NFRKB-RELATED 43.16 0.7550 44 Mapoly0189s0011 [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain 43.84 0.7959 45 Mapoly0214s0011 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 43.87 0.8000 46 Mapoly0002s0007 [GO:0003723] RNA binding; [GO:0001522] pseudouridine synthesis; [GO:0009451] RNA modification; [GO:0009982] pseudouridine synthase activity; [PF00849] RNA pseudouridylate synthase; [PTHR21600] RIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE SYNTHASE B; [PF01479] S4 domain 44.11 0.7241 47 Mapoly0013s0062 [GO:0003677] DNA binding; [PTHR15348:SF0] SUBFAMILY NOT NAMED; [PF01388] ARID/BRIGHT DNA binding domain; [GO:0005622] intracellular; [PTHR15348] AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN (ARID DOMAIN- CONTAINING PROTEIN) (DEAD RINGER PROTEIN) (B-CELL REGULATOR OF IGH TRANSCRIPTION) (BRIGHT) 44.16 0.7919 48 Mapoly0109s0044 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PF04057] Replication factor-A protein 1, N-terminal domain; [GO:0005634] nucleus; [KOG0851] Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins; [PF08646] Replication factor-A C terminal domain; [GO:0003676] nucleic acid binding; [K07466] replication factor A1; [PTHR23273] REPLICATION FACTOR A 1, RFA1; [PF01336] OB-fold nucleic acid binding domain 44.27 0.7777 49 Mapoly0051s0086 [PF05859] Mis12 protein; [GO:0007067] mitosis; [GO:0005634] nucleus; [GO:0000775] chromosome, centromeric region; [GO:0007049] cell cycle 46.43 0.7865 50 Mapoly0067s0049 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF00580] UvrD/REP helicase N-terminal domain; [PF13361] UvrD-like helicase C-terminal domain; [GO:0016787] hydrolase activity; [GO:0004003] ATP-dependent DNA helicase activity; [PTHR11070] UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER 50.38 0.7438 51 Mapoly0112s0022 [PTHR19932] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; [GO:0005515] protein binding; [KOG1274] WD40 repeat protein; [K11274] chromosome transmission fidelity protein 4; [PTHR19932:SF10] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN 1; [PF00400] WD domain, G-beta repeat; [PF12341] Protein of unknown function (DUF3639) 51.38 0.8006 52 Mapoly0014s0097 [PF13414] TPR repeat; [KOG1308] Hsp70-interacting protein Hip/Transient component of progesterone receptor complexes and an Hsp70-binding protein; [PTHR22904:SF34] HSC70-INTERACTING PROTEIN; [PTHR22904] TPR REPEAT CONTAINING PROTEIN 51.96 0.7769 53 Mapoly0043s0128 [KOG0381] HMG box-containing protein; [GO:0003677] DNA binding; [PF00505] HMG (high mobility group) box; [PF01388] ARID/BRIGHT DNA binding domain; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [GO:0005622] intracellular 52.65 0.7568 54 Mapoly0091s0013 [GO:0003723] RNA binding; [KOG2202] U2 snRNP splicing factor, small subunit, and related proteins; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PTHR12620] U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT; [GO:0005634] nucleus; [K12836] splicing factor U2AF 35 kDa subunit; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [GO:0046872] metal ion binding 53.44 0.7882 55 Mapoly0099s0061 [KOG1187] Serine/threonine protein kinase; [PF07714] Protein tyrosine kinase; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 53.48 0.7226 56 Mapoly0214s0010 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 54.66 0.7937 57 Mapoly0029s0121 [K11550] kinetochore protein Spc25, animal type; [PF08234] Chromosome segregation protein Spc25; [PTHR14281] FAMILY NOT NAMED 54.70 0.7949 58 Mapoly0077s0034 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 54.77 0.7281 59 Mapoly0111s0003 - 55.15 0.7514 60 Mapoly0006s0078 [GO:0005515] protein binding; [PTHR10253] POLYCOMB PROTEIN; [KOG1034] Transcriptional repressor EED/ESC/FIE, required for transcriptional silencing, WD repeat superfamily; [K11462] polycomb protein EED; [PF00400] WD domain, G-beta repeat 55.64 0.7538 61 Mapoly0021s0138 [KOG1548] Transcription elongation factor TAT-SF1; [GO:0005515] protein binding; [K13093] HIV Tat-specific factor 1; [PF02213] GYF domain; [PTHR15608] SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2; [PF14237] Domain of unknown function (DUF4339); [GO:0003676] nucleic acid binding; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 56.96 0.7602 62 Mapoly0098s0032 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [PF11721] Di-glucose binding within endoplasmic reticulum; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 57.39 0.7986 63 Mapoly0102s0037 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 60.16 0.7790 64 Mapoly0103s0079 [GO:0003677] DNA binding; [PTHR13763:SF0] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0005634] nucleus; [GO:0006281] DNA repair; [GO:0004842] ubiquitin-protein ligase activity; [KOG4362] Transcriptional regulator BRCA1; [PTHR13763] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; [PF13771] PHD-like zinc-binding domain 61.25 0.7970 65 Mapoly0007s0066 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PTHR19306:SF1] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5 SMC5; [KOG0979] Structural maintenance of chromosome protein SMC5/Spr18, SMC superfamily; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0000724] double-strand break repair via homologous recombination 61.43 0.7725 66 Mapoly0116s0028 [PTHR23074:SF19] KATANIN-RELATED; [GO:0005524] ATP binding; [3.6.4.3] Microtubule-severing ATPase.; [K07767] microtubule-severing ATPase [EC:3.6.4.3]; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0738] AAA+-type ATPase; [PTHR23074] AAA ATPASE; [PF09336] Vps4 C terminal oligomerisation domain 62.29 0.7419 67 Mapoly0001s0348 [KOG1342] Histone deacetylase complex, catalytic component RPD3; [PF00850] Histone deacetylase domain; [PTHR10625] HISTONE DEACETYLASE 63.17 0.7259 68 Mapoly0191s0002 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [K07374] tubulin alpha; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [KOG1376] Alpha tubulin; [GO:0005525] GTP binding 63.40 0.7559 69 Mapoly0086s0039 [PTHR12145:SF11] SUBFAMILY NOT NAMED; [PF03190] Protein of unknown function, DUF255; [KOG2244] Highly conserved protein containing a thioredoxin domain; [PTHR12145] UNCHARACTERIZED 63.45 0.6238 70 Mapoly0100s0038 [GO:0007264] small GTPase mediated signal transduction; [PTHR24073] FAMILY NOT NAMED; [KOG0098] GTPase Rab2, small G protein superfamily; [PF15305] Intraflagellar transport protein 43; [PF00071] Ras family; [GO:0005525] GTP binding; [GO:0030991] intraflagellar transport particle A 64.14 0.7303 71 Mapoly0051s0078 [GO:0006355] regulation of transcription, DNA-dependent; [KOG0266] WD40 repeat-containing protein; [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [PF00400] WD domain, G-beta repeat 64.99 0.7461 72 Mapoly0001s0105 [K02541] minichromosome maintenance protein 3; [KOG0479] DNA replication licensing factor, MCM3 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11630:SF46] DNA REPLICATION LICENSING FACTOR MCM3; [PF00493] MCM2/3/5 family; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 65.50 0.7954 73 Mapoly0087s0074 [GO:0005685] U1 snRNP; [PF06220] U1 zinc finger; [GO:0008270] zinc ion binding; [GO:0000398] mRNA splicing, via spliceosome; [KOG3454] U1 snRNP-specific protein C; [GO:0000387] spliceosomal snRNP assembly; [PTHR31148] FAMILY NOT NAMED 65.50 0.7654 74 Mapoly0074s0051 [GO:0000287] magnesium ion binding; [PTHR11902] ENOLASE; [PF03952] Enolase, N-terminal domain; [GO:0004634] phosphopyruvate hydratase activity; [GO:0006096] glycolysis; [PF00113] Enolase, C-terminal TIM barrel domain; [4.2.1.11] Phosphopyruvate hydratase.; [GO:0000015] phosphopyruvate hydratase complex; [K01689] enolase [EC:4.2.1.11]; [KOG2670] Enolase 65.95 0.7169 75 Mapoly0002s0271 - 67.96 0.7175 76 Mapoly0051s0085 [KOG2267] Eukaryotic-type DNA primase, large subunit; [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10537] DNA PRIMASE LARGE SUBUNIT; [K02685] DNA primase large subunit [EC:2.7.7.-]; [PF04104] Eukaryotic and archaeal DNA primase, large subunit; [2.7.7.-] Nucleotidyltransferases. 68.68 0.7695 77 Mapoly0036s0154 [KOG2606] OTU (ovarian tumor)-like cysteine protease; [PTHR12419] OTU DOMAIN CONTAINING PROTEIN; [PTHR12419:SF10] gb def: ENSANGP00000019868 (Fragment); [PF02338] OTU-like cysteine protease 68.78 0.7628 78 Mapoly0029s0136 [PTHR21206:SF0] SUBFAMILY NOT NAMED; [PF05916] GINS complex protein; [KOG3176] Predicted alpha-helical protein, potentially involved in replication/repair; [PTHR21206] SLD5 PROTEIN; [K10735] GINS complex subunit 4 70.72 0.7584 79 Mapoly0038s0027 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PTHR10629:SF11] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF12047] Cytosine specific DNA methyltransferase replication foci domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 70.87 0.7485 80 Mapoly0159s0020 [K05544] tRNA-dihydrouridine synthase 3 [EC:1.-.-.-]; [GO:0050660] flavin adenine dinucleotide binding; [GO:0055114] oxidation-reduction process; [PTHR11082:SF8] TRNA-DIHYDROURIDINE SYNTHASE 3; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PF01207] Dihydrouridine synthase (Dus); [KOG2333] Uncharacterized conserved protein; [GO:0008033] tRNA processing; [PTHR11082] TRNA-DIHYDROURIDINE SYNTHASE; [GO:0046872] metal ion binding; [GO:0017150] tRNA dihydrouridine synthase activity; [1.-.-.-] Oxidoreductases. 70.99 0.7453 81 Mapoly0009s0056 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PF08311] Mad3/BUB1 homology region 1; [K02178] checkpoint serine/threonine-protein kinase [EC:2.7.11.1]; [KOG1166] Mitotic checkpoint serine/threonine protein kinase; [PTHR14030] MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 71.33 0.7778 82 Mapoly0015s0164 [GO:0003677] DNA binding; [PF02362] B3 DNA binding domain; [PTHR31391] FAMILY NOT NAMED 72.97 0.7528 83 Mapoly0089s0025 - 73.57 0.7075 84 Mapoly0123s0001 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 74.88 0.7578 85 Mapoly0016s0108 [GO:0005524] ATP binding; [K10755] replication factor C subunit 2/4; [KOG0991] Replication factor C, subunit RFC2; [PTHR11669] REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08542] Replication factor C C-terminal domain 75.47 0.7458 86 Mapoly0179s0001 [PTHR10994] RETICULON; [PF02453] Reticulon; [KOG1792] Reticulon 76.73 0.7804 87 Mapoly0034s0119 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 78.94 0.7892 88 Mapoly0061s0132 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity; [KOG0246] Kinesin-like protein; [K10393] kinesin family member 2/24 78.99 0.7126 89 Mapoly0135s0035 [GO:0003676] nucleic acid binding; [PF02037] SAP domain 82.06 0.7531 90 Mapoly0189s0010 [PTHR15272:SF0] SUBFAMILY NOT NAMED; [PF12253] Chromatin assembly factor 1 subunit A; [PTHR15272] CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A (CAF-1 SUBUNIT A) 83.41 0.7416 91 Mapoly0070s0078 [GO:0008080] N-acetyltransferase activity; [PF00583] Acetyltransferase (GNAT) family; [PTHR13355] GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE; [PTHR13355:SF2] gb def: acetyltransferase (gnat) family [caenorhabditis elegans] 83.89 0.6089 92 Mapoly0036s0153 [PTHR10971:SF5] MITOTIC CHECKPOINT PROTEIN BUB3; [PTHR10971] MRNA EXPORT FACTOR AND BUB3; [GO:0005515] protein binding; [K02180] cell cycle arrest protein BUB3; [KOG1036] Mitotic spindle checkpoint protein BUB3, WD repeat superfamily; [PF00400] WD domain, G-beta repeat 84.10 0.7722 93 Mapoly0014s0033 [KOG4285] Mitotic phosphoprotein; [PTHR21527] FAMILY NOT NAMED; [K14313] nuclear pore complex protein Nup53; [PF05172] Nup53/35/40-type RNA recognition motif 84.50 0.7236 94 Mapoly0029s0045 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0243] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [PF12711] Kinesin motor; [GO:0003777] microtubule motor activity; [K10400] kinesin family member 15 84.66 0.7267 95 Mapoly0105s0026 - 84.84 0.7296 96 Mapoly0069s0082 [PTHR23002] ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding 85.99 0.7467 97 Mapoly0001s0330 [PTHR11210] RING BOX; [PF12861] Anaphase-promoting complex subunit 11 RING-H2 finger; [K03358] anaphase-promoting complex subunit 11; [GO:0004842] ubiquitin-protein ligase activity; [GO:0005680] anaphase-promoting complex 87.18 0.7415 98 Mapoly0013s0011 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 88.54 0.7489 99 Mapoly0038s0098 [K03351] anaphase-promoting complex subunit 4; [PF12896] Anaphase-promoting complex, cyclosome, subunit 4; [KOG4640] Anaphase-promoting complex (APC), subunit 4; [GO:0030071] regulation of mitotic metaphase/anaphase transition; [PF12894] Anaphase-promoting complex subunit 4 WD40 domain; [PTHR13260] ANAPHASE PROMOTING COMPLEX SUBUNIT 4 (APC4) (CYCLOSOME SUBUNIT 4); [GO:0005680] anaphase-promoting complex; [GO:0031145] anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 89.10 0.7097 100 Mapoly0061s0010 [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10536] DNA PRIMASE SMALL SUBUNIT; [KOG2851] Eukaryotic-type DNA primase, catalytic (small) subunit; [K02684] DNA primase small subunit [EC:2.7.7.-]; [2.7.7.-] Nucleotidyltransferases.; [PF01896] Eukaryotic and archaeal DNA primase small subunit 89.47 0.7626 101 Mapoly0098s0043 [PF12717] non-SMC mitotic condensation complex subunit 1; [GO:0007076] mitotic chromosome condensation; [K11491] condensin-2 complex subunit D3; [PTHR14222:SF1] CONDENSIN; [PTHR14222] CONDENSIN 90.11 0.7635 102 Mapoly0007s0014 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02540] minichromosome maintenance protein 2; [PF12619] Mini-chromosome maintenance protein 2; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PTHR11630:SF44] DNA REPLICATION LICENSING FACTOR MCM2; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [KOG0477] DNA replication licensing factor, MCM2 component 90.60 0.7661 103 Mapoly0006s0255 [GO:0003723] RNA binding; [PTHR10288] KH DOMAIN CONTAINING RNA BINDING PROTEIN; [PF00013] KH domain; [KOG2192] PolyC-binding hnRNP-K protein HRB57A/hnRNP, contains KH domain; [K13210] far upstream element-binding protein 92.91 0.7483 104 Mapoly0042s0032 [PF13259] Protein of unknown function (DUF4050) 93.67 0.7484 105 Mapoly0001s0273 [PTHR10501] U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B; [PTHR10501:SF0] SMALL NUCLEAR RIBONUCLEOPROTEIN; [GO:0000398] mRNA splicing, via spliceosome; [GO:0003676] nucleic acid binding; [GO:0017069] snRNA binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 94.20 0.7397 106 Mapoly0207s0009 [PTHR10241] LETHAL(2) GIANT LARVAE PROTEIN; [GO:0016192] vesicle-mediated transport; [GO:0016021] integral to membrane; [PTHR10241:SF25] SUBFAMILY NOT NAMED; [PF00957] Synaptobrevin 94.49 0.6654 107 Mapoly0046s0087 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PTHR24420:SF145] SUBFAMILY NOT NAMED; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 94.92 0.6589 108 Mapoly0024s0100 [GO:0005524] ATP binding; [PTHR11669] REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; [KOG0990] Replication factor C, subunit RFC5; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08542] Replication factor C C-terminal domain; [K10756] replication factor C subunit 3/5 94.99 0.7576 109 Mapoly0059s0079 [KOG2014] SMT3/SUMO-activating complex, AOS1/RAD31 component; [PF00899] ThiF family; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [K10684] ubiquitin-like 1-activating enzyme E1 A [EC:6.3.2.19] 95.52 0.7535 110 Mapoly0125s0042 [GO:0016758] transferase activity, transferring hexosyl groups; [2.4.1.218] Hydroquinone glucosyltransferase.; [K08237] hydroquinone glucosyltransferase [EC:2.4.1.218]; [PF00201] UDP-glucoronosyl and UDP-glucosyl transferase; [PTHR11926] GLUCOSYL/GLUCURONOSYL TRANSFERASES; [GO:0008152] metabolic process; [KOG1192] UDP-glucuronosyl and UDP-glucosyl transferase 95.71 0.6742 111 Mapoly0024s0031 [PTHR11525:SF0] SUBFAMILY NOT NAMED; [PTHR11525] FARNESYL-PYROPHOSPHATE SYNTHETASE; [2.5.1.1] Dimethylallyltranstransferase.; [GO:0008299] isoprenoid biosynthetic process; [PF00348] Polyprenyl synthetase; [KOG0711] Polyprenyl synthetase; [2.5.1.10] (2E,6E)-farnesyl diphosphate synthase.; [K00787] farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] 95.95 0.6527 112 Mapoly0002s0191 [GO:0008168] methyltransferase activity; [PTHR10108] METHYLTRANSFERASE; [PF08241] Methyltransferase domain; [GO:0008152] metabolic process; [KOG4300] Predicted methyltransferase 96.66 0.6490 113 Mapoly0011s0143 [PTHR15481:SF0] SUBFAMILY NOT NAMED; [K14325] RNA-binding protein with serine-rich domain 1; [PTHR15481] RIBONUCLEIC ACID BINDING PROTEIN S1; [GO:0003676] nucleic acid binding; [KOG0130] RNA-binding protein RBM8/Tsunagi (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 96.82 0.7469 114 Mapoly0001s0015 [PTHR13555] C2H2 ZINC FINGER CGI-62-RELATED 96.95 0.6966 115 Mapoly0172s0018 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 97.82 0.7388 116 Mapoly0003s0086 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 98.61 0.7559 117 Mapoly0063s0098 [PF04770] ZF-HD protein dimerisation region; [PTHR31948] FAMILY NOT NAMED 100.10 0.7064 118 Mapoly0001s0442 [PF12600] Protein of unknown function (DUF3769) 100.57 0.5295 119 Mapoly0105s0028 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 101.03 0.7341 120 Mapoly0120s0003 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [K07374] tubulin alpha; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [KOG1376] Alpha tubulin; [GO:0005525] GTP binding 102.18 0.6300 121 Mapoly0005s0196 [PTHR24011] FAMILY NOT NAMED; [PF04059] RNA recognition motif 2; [GO:0003676] nucleic acid binding; [KOG4660] Protein Mei2, essential for commitment to meiosis, and related proteins; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 103.92 0.7363 122 Mapoly0039s0001 - 104.04 0.7260 123 Mapoly0081s0021 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF07645] Calcium-binding EGF domain; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PF13947] Wall-associated receptor kinase galacturonan-binding; [GO:0030247] polysaccharide binding; [GO:0006468] protein phosphorylation; [GO:0005509] calcium ion binding; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 106.25 0.6828 124 Mapoly0035s0099 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02321] DNA polymerase alpha subunit B; [PTHR23061:SF12] SUBFAMILY NOT NAMED; [KOG1625] DNA polymerase alpha-primase complex, polymerase-associated subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [PTHR23061] DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; [GO:0003887] DNA-directed DNA polymerase activity; [PF08418] DNA polymerase alpha subunit B N-terminal 106.92 0.7548 125 Mapoly0106s0044 [PF03980] Nnf1 107.50 0.6814 126 Mapoly0005s0256 [PF12220] U1 small nuclear ribonucleoprotein of 70kDa MW N terminal; [KOG0113] U1 small nuclear ribonucleoprotein (RRM superfamily); [PTHR13952:SF5] PREDICTED: HYPOTHETICAL PROTEIN, PARTIAL; [PTHR13952] U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD; [K11093] U1 small nuclear ribonucleoprotein 70kDa; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 107.75 0.7267 127 Mapoly0011s0202 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain 107.89 0.7595 128 Mapoly0051s0023 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III 108.25 0.7578 129 Mapoly0039s0120 [KOG1805] DNA replication helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PTHR10887:SF14] DNA2-LIKE HELICASE; [3.6.4.12] DNA helicase.; [PF13086] AAA domain; [GO:0033567] DNA replication, Okazaki fragment processing; [PF01930] Domain of unknown function DUF83; [GO:0017108] 5'-flap endonuclease activity; [GO:0043142] single-stranded DNA-dependent ATPase activity; [PF13087] AAA domain; [PF08696] DNA replication factor Dna2; [K10742] DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12] 108.66 0.7211 130 Mapoly0002s0035 - 109.44 0.7347 131 Mapoly0087s0081 - 112.06 0.6564 132 Mapoly0026s0047 [PF03226] Yippee zinc-binding/DNA-binding /Mis18, centromere assembly; [PTHR13847] FAD NAD BINDING OXIDOREDUCTASES; [KOG3399] Predicted Yippee-type zinc-binding protein 113.60 0.5927 133 Mapoly0081s0071 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [PF00628] PHD-finger; [GO:0005515] protein binding; [PF12738] twin BRCT domain; [GO:0046872] metal ion binding 114.78 0.7475 134 Mapoly0089s0046 [K06688] ubiquitin-conjugating enzyme E2 C [EC:6.3.2.19]; [PTHR24067:SF44] UBIQUITIN-CONJUGATING ENZYME E2 C; [PTHR24067] UBIQUITIN-CONJUGATING ENZYME E2; [GO:0016881] acid-amino acid ligase activity; [6.3.2.19] Ubiquitin--protein ligase.; [PF00179] Ubiquitin-conjugating enzyme; [KOG0421] Ubiquitin-protein ligase 115.45 0.7247 135 Mapoly0031s0046 [PF06521] PAR1 protein 115.49 0.6725 136 Mapoly0120s0004 [PF00488] MutS domain V; [GO:0005524] ATP binding; [K08735] DNA mismatch repair protein MSH2; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PTHR11361:SF35] MUTS HOMOLOG 2, MSH2; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III; [KOG0219] Mismatch repair ATPase MSH2 (MutS family); [PF05190] MutS family domain IV 116.16 0.7391 137 Mapoly0027s0147 [PTHR12585] SCC1 / RAD21 FAMILY MEMBER; [PF04824] Conserved region of Rad21 / Rec8 like protein; [GO:0005515] protein binding; [PF04825] N terminus of Rad21 / Rec8 like protein; [K06670] cohesin complex subunit SCC1; [GO:0000228] nuclear chromosome; [KOG1213] Sister chromatid cohesion complex Cohesin, subunit RAD21/SCC1 116.49 0.7319 138 Mapoly0021s0156 [GO:0016020] membrane; [GO:0005524] ATP binding; [PF08370] Plant PDR ABC transporter associated; [GO:0016887] ATPase activity; [PTHR19241] ATP-BINDING CASSETTE TRANSPORTER; [PF01061] ABC-2 type transporter; [PF14510] ABC-transporter extracellular N-terminal; [KOG0065] Pleiotropic drug resistance proteins (PDR1-15), ABC superfamily; [PF00005] ABC transporter 116.64 0.6992 139 Mapoly0146s0045 [GO:0003723] RNA binding; [PTHR11207:SF1] RIBONUCLEASE III; [PF00035] Double-stranded RNA binding motif; [GO:0004525] ribonuclease III activity; [GO:0016075] rRNA catabolic process; [PTHR11207] RIBONUCLEASE III 117.73 0.7375 140 Mapoly0177s0008 [GO:0006260] DNA replication; [PF13191] AAA ATPase domain; [GO:0005634] nucleus; [KOG2543] Origin recognition complex, subunit 5; [PF14630] Origin recognition complex (ORC) subunit 5 C-terminus; [PTHR12705] ORIGIN RECOGNITION COMPLEX SUBUNIT 5; [GO:0000808] origin recognition complex; [K02607] origin recognition complex subunit 5 117.86 0.7445 141 Mapoly0001s0238 [PF02978] Signal peptide binding domain; [GO:0048500] signal recognition particle; [PF00448] SRP54-type protein, GTPase domain; [GO:0008312] 7S RNA binding; [K03106] signal recognition particle subunit SRP54; [KOG0780] Signal recognition particle, subunit Srp54; [GO:0006614] SRP-dependent cotranslational protein targeting to membrane; [PF02881] SRP54-type protein, helical bundle domain; [GO:0005525] GTP binding; [PTHR11564:SF5] SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN; [PTHR11564] GTPASE CONTAINING FAMILY OF SIGNAL RECOGNITION PARTICLE PROTEINS 117.98 0.6685 142 Mapoly0001s0064 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [GO:0008173] RNA methyltransferase activity; [PTHR12029] RNA METHYLTRANSFERASE; [KOG0838] RNA Methylase, SpoU family; [PF00588] SpoU rRNA Methylase family 118.26 0.7357 143 Mapoly0021s0043 - 118.49 0.7266 144 Mapoly0028s0110 [GO:0005524] ATP binding; [PTHR23069] TAT-BINDING HOMOLOG 7; [PTHR23069:SF0] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [PF00439] Bromodomain; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0732] AAA+-type ATPase containing the bromodomain 118.66 0.7363 145 Mapoly0103s0053 [GO:0008168] methyltransferase activity; [PTHR23068:SF3] gb def: Hypothetical protein T15N1_120; [PTHR23068] DNA (CYTOSINE-5-)-METHYLTRANSFERASE 3-RELATED; [PF00145] C-5 cytosine-specific DNA methylase 118.89 0.6742 146 Mapoly0043s0082 [PF07899] Frigida-like protein; [PTHR31791] FAMILY NOT NAMED 119.29 0.7133 147 Mapoly0051s0067 [PF00651] BTB/POZ domain; [PTHR24411] FAMILY NOT NAMED; [PF00917] MATH domain; [GO:0005515] protein binding; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 120.86 0.6794 148 Mapoly0158s0006 - 121.42 0.7336 149 Mapoly0005s0208 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [KOG0244] Kinesin-like protein; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [K10395] kinesin family member 4/7/21/27; [GO:0003777] microtubule motor activity 121.47 0.7313 150 Mapoly0036s0107 [K09422] myb proto-oncogene protein, plant; [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding; [PF13921] Myb-like DNA-binding domain 121.82 0.7374 151 Mapoly0001s0501 [PF12681] Glyoxalase-like domain 122.62 0.7128 152 Mapoly0086s0078 [GO:0003677] DNA binding; [GO:0006275] regulation of DNA replication; [GO:0030337] DNA polymerase processivity factor activity; [PTHR11352] PROLIFERATING CELL NUCLEAR ANTIGEN; [PF00705] Proliferating cell nuclear antigen, N-terminal domain; [KOG1636] DNA polymerase delta processivity factor (proliferating cell nuclear antigen); [PF02747] Proliferating cell nuclear antigen, C-terminal domain 123.87 0.7245 153 Mapoly0004s0096 [K11548] kinetochore protein Nuf2; [GO:0007067] mitosis; [PTHR21650] MEMBRALIN/KINETOCHORE PROTEIN NUF2; [PF03800] Nuf2 family; [KOG4438] Centromere-associated protein NUF2; [GO:0000775] chromosome, centromeric region; [PTHR21650:SF2] KINETOCHORE PROTEIN NUF2 124.01 0.7446 154 Mapoly0063s0059 [GO:0000812] Swr1 complex; [GO:0006338] chromatin remodeling; [GO:0006355] regulation of transcription, DNA-dependent; [GO:0031011] Ino80 complex; [PTHR11937:SF47] SUBFAMILY NOT NAMED; [GO:0035267] NuA4 histone acetyltransferase complex; [PF00022] Actin; [GO:0006281] DNA repair; [PTHR11937] ACTIN; [KOG0679] Actin-related protein - Arp4p/Act3p 124.97 0.7099 155 Mapoly0084s0051 [2.1.1.43] Histone-lysine N-methyltransferase.; [GO:0005515] protein binding; [PF00856] SET domain; [KOG1079] Transcriptional repressor EZH1; [PTHR22884] SET DOMAIN PROTEINS; [K11430] enhancer of zeste [EC:2.1.1.43] 125.06 0.6970 156 Mapoly0046s0055 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [KOG1374] Gamma tubulin; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [GO:0031122] cytoplasmic microtubule organization; [PTHR11588:SF7] TUBULIN GAMMA CHAIN; [K10389] tubulin gamma; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0007020] microtubule nucleation; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0000930] gamma-tubulin complex; [GO:0043234] protein complex; [GO:0005525] GTP binding 125.22 0.7105 157 Mapoly0096s0020 [GO:0005524] ATP binding; [PF02359] Cell division protein 48 (CDC48), N-terminal domain; [PF02933] Cell division protein 48 (CDC48), domain 2; [PF00004] ATPase family associated with various cellular activities (AAA); [K13525] transitional endoplasmic reticulum ATPase; [PTHR23077] AAA-FAMILY ATPASE; [KOG0730] AAA+-type ATPase 126.28 0.7253 158 Mapoly0051s0073 [PF14675] FANCI solenoid 1; [PTHR21818:SF0] SUBFAMILY NOT NAMED; [PF14680] FANCI helical domain 2; [KOG4553] Uncharacterized conserved protein; [K10895] fanconi anemia group I protein; [PF14679] FANCI helical domain 1; [GO:0006281] DNA repair; [PF14678] FANCI solenoid 4; [PTHR21818] BC025462 PROTEIN; [PF14676] FANCI solenoid 2 126.33 0.7345 159 Mapoly0049s0118 [PTHR32002] FAMILY NOT NAMED; [PF02042] RWP-RK domain 126.57 0.6941 160 Mapoly0006s0250 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 126.73 0.7197 161 Mapoly0068s0100 [GO:0003872] 6-phosphofructokinase activity; [2.7.1.90] Diphosphate--fructose-6-phosphate 1-phosphotransferase.; [K00895] pyrophosphate--fructose-6-phosphate 1-phosphotransferase [EC:2.7.1.90]; [GO:0006096] glycolysis; [PF00365] Phosphofructokinase; [KOG2440] Pyrophosphate-dependent phosphofructo-1-kinase; [PTHR13697] PHOSPHOFRUCTOKINASE 128.49 0.6638 162 Mapoly0060s0012 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [K11498] centromeric protein E; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 128.94 0.7425 163 Mapoly0030s0102 [PF08317] Spc7 kinetochore protein 129.74 0.7440 164 Mapoly0028s0082 - 129.98 0.6600 165 Mapoly0027s0105 - 131.87 0.6967 166 Mapoly0028s0075 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [K11251] histone H2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 133.60 0.7549 167 Mapoly0099s0055 [GO:0016020] membrane; [PTHR11654] OLIGOPEPTIDE TRANSPORTER-RELATED; [PF00854] POT family; [KOG1237] H+/oligopeptide symporter; [GO:0006810] transport; [GO:0005215] transporter activity 133.60 0.6832 168 Mapoly0105s0060 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [K12898] heterogeneous nuclear ribonucleoprotein F/H; [KOG4211] Splicing factor hnRNP-F and related RNA-binding proteins; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED 133.63 0.7420 169 Mapoly0166s0018 [K10739] replication factor A2; [KOG3108] Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit; [PF08784] Replication protein A C terminal; [PTHR13989] REPLICATION PROTEIN A-RELATED; [GO:0003676] nucleic acid binding; [PF01336] OB-fold nucleic acid binding domain 134.60 0.7415 170 Mapoly0043s0062 [GO:0003677] DNA binding; [GO:0006284] base-excision repair; [PTHR10359] A/G-SPECIFIC ADENINE GLYCOSYLASE/ENDONUCLEASE III; [PF14815] NUDIX domain; [K03575] A/G-specific adenine glycosylase [EC:3.2.2.-]; [KOG1921] Endonuclease III; [PF00730] HhH-GPD superfamily base excision DNA repair protein; [PF00633] Helix-hairpin-helix motif; [3.2.2.-] Hydrolyzing N-glycosyl compounds. 135.39 0.6934 171 Mapoly0133s0052 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K08851] TP53 regulating kinase [EC:2.7.11.1]; [PTHR12209] O-SIALOGLYCOPROTEIN ENDOPEPTIDASE; [GO:0006468] protein phosphorylation; [KOG3087] Serine/threonine protein kinase; [GO:0004674] protein serine/threonine kinase activity 136.17 0.7269 172 Mapoly0029s0012 [GO:0005524] ATP binding; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [KOG0329] ATP-dependent RNA helicase; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding 137.17 0.7353 173 Mapoly0081s0013 [PTHR32133] FAMILY NOT NAMED; [GO:0005515] protein binding; [PF00646] F-box domain 137.83 0.6091 174 Mapoly0062s0108 [GO:0005524] ATP binding; [2.7.11.26] [Tau protein] kinase.; [PF00069] Protein kinase domain; [KOG0658] Glycogen synthase kinase-3; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24057] GLYCOGEN SYNTHASE KINASE-3 ALPHA; [K03083] glycogen synthase kinase 3 beta [EC:2.7.11.26] 138.79 0.7033 175 Mapoly0091s0017 [GO:0005515] protein binding; [PTHR22937] RING FINGER CONTAINING PROTEIN; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [KOG2177] Predicted E3 ubiquitin ligase; [K11985] TRAF-interacting protein 138.89 0.6952 176 Mapoly0083s0014 [GO:0016020] membrane; [GO:0005524] ATP binding; [KOG0061] Transporter, ABC superfamily (Breast cancer resistance protein); [PF08370] Plant PDR ABC transporter associated; [GO:0016887] ATPase activity; [PTHR19241] ATP-BINDING CASSETTE TRANSPORTER; [PF01061] ABC-2 type transporter; [PF14510] ABC-transporter extracellular N-terminal; [PF00005] ABC transporter 139.21 0.6198 177 Mapoly0091s0060 - 139.82 0.6740 178 Mapoly0126s0040 [PTHR11062] EXOSTOSIN (HEPARAN SULFATE GLYCOSYLTRANSFERASE)-RELATED; [KOG1021] Acetylglucosaminyltransferase EXT1/exostosin 1; [PF03016] Exostosin family 140.97 0.6538 179 Mapoly0099s0053 [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 141.11 0.7153 180 Mapoly0022s0167 [PF12717] non-SMC mitotic condensation complex subunit 1; [PF12922] non-SMC mitotic condensation complex subunit 1, N-term; [GO:0007076] mitotic chromosome condensation; [PTHR14222] CONDENSIN; [KOG0414] Chromosome condensation complex Condensin, subunit D2; [K06677] condensin complex subunit 1 141.45 0.7367 181 Mapoly0005s0021 [PF13266] Protein of unknown function (DUF4057); [PTHR31132] FAMILY NOT NAMED 142.84 0.7404 182 Mapoly0081s0019 [PF00083] Sugar (and other) transporter; [GO:0016021] integral to membrane; [GO:0055085] transmembrane transport; [KOG0255] Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily); [PTHR24064] FAMILY NOT NAMED; [GO:0022857] transmembrane transporter activity 142.91 0.5993 183 Mapoly0005s0067 [PTHR15242:SF0] SUBFAMILY NOT NAMED; [PTHR15242] SPLICING FACTOR, ARGININE/SERINE-RICH 2,RNAP C-TERM INTERACTING PROTEIN; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 144.08 0.7306 184 Mapoly0048s0012 [GO:0015035] protein disulfide oxidoreductase activity; [KOG1752] Glutaredoxin and related proteins; [PTHR10168] GLUTAREDOXIN; [GO:0045454] cell redox homeostasis; [PF00462] Glutaredoxin; [GO:0009055] electron carrier activity 144.33 0.5887 185 Mapoly0144s0027 [PTHR12872] ALPHA-N-ACETYLGLUCOSAMINIDASE; [KOG2233] Alpha-N-acetylglucosaminidase; [PF05089] Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain; [K01205] alpha-N-acetylglucosaminidase [EC:3.2.1.50]; [3.2.1.50] Alpha-N-acetylglucosaminidase.; [PF12972] Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain; [PF12971] Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain 145.07 0.6974 186 Mapoly0042s0088 [PF03801] HEC/Ndc80p family; [K11547] kinetochore protein NDC80; [PTHR10643] KINETOCHORE PROTEIN NDC80; [KOG0995] Centromere-associated protein HEC1 145.19 0.7288 187 Mapoly0086s0063 [GO:0005506] iron ion binding; [GO:0055114] oxidation-reduction process; [PTHR12863] FATTY ACID HYDROXYLASE; [KOG0539] Sphingolipid fatty acid hydroxylase; [GO:0006633] fatty acid biosynthetic process; [GO:0016491] oxidoreductase activity; [GO:0020037] heme binding; [PF04116] Fatty acid hydroxylase superfamily; [PF00173] Cytochrome b5-like Heme/Steroid binding domain 146.10 0.5500 188 Mapoly0004s0213 [PF03215] Rad17 cell cycle checkpoint protein; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PTHR12172] CELL CYCLE CHECKPOINT PROTEIN RAD17; [KOG1970] Checkpoint RAD17-RFC complex, RAD17/RAD24 component; [PTHR12172:SF0] SUBFAMILY NOT NAMED; [K06662] cell cycle checkpoint protein; [GO:0007049] cell cycle 146.74 0.6940 189 Mapoly0061s0107 [GO:0003677] DNA binding; [KOG0483] Transcription factor HEX, contains HOX and HALZ domains; [PF00046] Homeobox domain; [PF08670] MEKHLA domain; [PF01852] START domain; [PTHR24326] FAMILY NOT NAMED; [GO:0008289] lipid binding; [K09338] homeobox-leucine zipper protein 146.83 0.6663 190 Mapoly0028s0066 [GO:0005524] ATP binding; [KOG1112] Ribonucleotide reductase, alpha subunit; [GO:0006260] DNA replication; [GO:0055114] oxidation-reduction process; [GO:0004748] ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; [PF00317] Ribonucleotide reductase, all-alpha domain; [PTHR11573] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN; [PTHR11573:SF6] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN; [PF02867] Ribonucleotide reductase, barrel domain; [1.17.4.1] Ribonucleoside-diphosphate reductase.; [K10807] ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]; [PF03477] ATP cone domain 147.40 0.7228 191 Mapoly0132s0046 [PF00855] PWWP domain; [PTHR12550] HEPATOMA-DERIVED GROWTH FACTOR-RELATED; [PTHR12550:SF5] UNCHARACTERIZED 149.24 0.6946 192 Mapoly0010s0132 [KOG4825] Component of synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine-binding glycoprotein (43kDa); [PF02151] UvrB/uvrC motif; [GO:0005515] protein binding; [PTHR13371] GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN; [PTHR13371:SF0] SUBFAMILY NOT NAMED 149.48 0.6472 193 Mapoly0030s0056 [PF00134] Cyclin, N-terminal domain; [PTHR10177] CYCLINE; [PF02984] Cyclin, C-terminal domain; [GO:0005634] nucleus; [KOG0656] G1/S-specific cyclin D 151.06 0.7076 194 Mapoly0056s0069 [PF00645] Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region; [GO:0003677] DNA binding; [PTHR12083] POLYNUCLEOTIDE KINASE- 3'-PHOSPHATASE; [PF08645] Polynucleotide kinase 3 phosphatase; [K08073] bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]; [3.1.3.32] Polynucleotide 3'-phosphatase.; [GO:0008270] zinc ion binding; [2.7.1.78] Polynucleotide 5'-hydroxyl-kinase. 151.94 0.6671 195 Mapoly0114s0009 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [PF00514] Armadillo/beta-catenin-like repeat; [GO:0005515] protein binding; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [KOG0240] Kinesin (SMY1 subfamily); [GO:0008017] microtubule binding; [PTHR24115:SF221] SUBFAMILY NOT NAMED; [GO:0003777] microtubule motor activity 152.79 0.6871 196 Mapoly0003s0057 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination 154.29 0.7341 197 Mapoly0005s0130 [GO:0042393] histone binding; [PF02182] SAD/SRA domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF13923] Zinc finger, C3HC4 type (RING finger); [PTHR14140] E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED 155.02 0.6995 198 Mapoly0063s0094 - 156.57 0.6692 199 Mapoly0073s0079 [GO:0046907] intracellular transport; [GO:0005643] nuclear pore; [PTHR23138] RAN BINDING PROTEIN; [PTHR23138:SF46] ABR034WP; [PF00638] RanBP1 domain; [PF08911] NUP50 (Nucleoporin 50 kDa) 157.80 0.7064 200 Mapoly0113s0037 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [KOG2577] Transcription factor E2F/dimerization partner (TDP); [PTHR12081] TRANSCRIPTION FACTOR E2F 158.93 0.7031