| 1 |
Mapoly0103s0079
| [GO:0003677] DNA binding; [PTHR13763:SF0] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0005634] nucleus; [GO:0006281] DNA repair; [GO:0004842] ubiquitin-protein ligase activity; [KOG4362] Transcriptional regulator BRCA1; [PTHR13763] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; [PF13771] PHD-like zinc-binding domain | 7.94 | 0.8605 |
| 2 |
Mapoly0006s0287
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02209] minichromosome maintenance protein 5 (cell division control protein 46); [PTHR11630:SF42] DNA REPLICATION LICENSING FACTOR MCM5; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain; [KOG0481] DNA replication licensing factor, MCM5 component | 9.38 | 0.8543 |
| 3 |
Mapoly0166s0018
| [K10739] replication factor A2; [KOG3108] Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit; [PF08784] Replication protein A C terminal; [PTHR13989] REPLICATION PROTEIN A-RELATED; [GO:0003676] nucleic acid binding; [PF01336] OB-fold nucleic acid binding domain | 9.64 | 0.8530 |
| 4 |
Mapoly0109s0044
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PF04057] Replication factor-A protein 1, N-terminal domain; [GO:0005634] nucleus; [KOG0851] Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins; [PF08646] Replication factor-A C terminal domain; [GO:0003676] nucleic acid binding; [K07466] replication factor A1; [PTHR23273] REPLICATION FACTOR A 1, RFA1; [PF01336] OB-fold nucleic acid binding domain | 10.68 | 0.8326 |
| 5 |
Mapoly0046s0055
| [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [KOG1374] Gamma tubulin; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [GO:0031122] cytoplasmic microtubule organization; [PTHR11588:SF7] TUBULIN GAMMA CHAIN; [K10389] tubulin gamma; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0007020] microtubule nucleation; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0000930] gamma-tubulin complex; [GO:0043234] protein complex; [GO:0005525] GTP binding | 11.18 | 0.8241 |
| 6 |
Mapoly0064s0110
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR13394] ORIGIN RECOGNITION COMPLEX SUBUNIT 6; [PF05460] Origin recognition complex subunit 6 (ORC6); [GO:0005664] nuclear origin of replication recognition complex; [K02608] origin recognition complex subunit 6; [PTHR13394:SF0] SUBFAMILY NOT NAMED; [KOG4557] Origin recognition complex, subunit 6 | 12.00 | 0.8490 |
| 7 |
Mapoly0043s0112
| [PTHR21780] UNCHARACTERIZED; [KOG4670] Uncharacterized conserved membrane protein; [PTHR21780:SF0] SUBFAMILY NOT NAMED; [PF09786] Cytochrome B561, N terminal | 13.08 | 0.8446 |
| 8 |
Mapoly0002s0035
| - | 13.27 | 0.8351 |
| 9 |
Mapoly0145s0029
| - | 14.73 | 0.8131 |
| 10 |
Mapoly0055s0064
| - | 15.49 | 0.8470 |
| 11 |
Mapoly0053s0016
| [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B | 15.75 | 0.8454 |
| 12 |
Mapoly0029s0121
| [K11550] kinetochore protein Spc25, animal type; [PF08234] Chromosome segregation protein Spc25; [PTHR14281] FAMILY NOT NAMED | 16.09 | 0.8461 |
| 13 |
Mapoly0119s0016
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [KOG0480] DNA replication licensing factor, MCM6 component; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630:SF43] DNA REPLICATION LICENSING FACTOR MCM6; [K02542] minichromosome maintenance protein 6; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain | 16.28 | 0.8478 |
| 14 |
Mapoly0060s0031
| - | 16.61 | 0.7902 |
| 15 |
Mapoly0037s0034
| [K10744] ribonuclease H2 subunit B; [PTHR13383] FAMILY NOT NAMED; [PF09468] Ydr279p protein family (RNase H2 complex component); [GO:0005634] nucleus | 17.55 | 0.8433 |
| 16 |
Mapoly0001s0330
| [PTHR11210] RING BOX; [PF12861] Anaphase-promoting complex subunit 11 RING-H2 finger; [K03358] anaphase-promoting complex subunit 11; [GO:0004842] ubiquitin-protein ligase activity; [GO:0005680] anaphase-promoting complex | 20.20 | 0.8054 |
| 17 |
Mapoly0029s0136
| [PTHR21206:SF0] SUBFAMILY NOT NAMED; [PF05916] GINS complex protein; [KOG3176] Predicted alpha-helical protein, potentially involved in replication/repair; [PTHR21206] SLD5 PROTEIN; [K10735] GINS complex subunit 4 | 21.35 | 0.8291 |
| 18 |
Mapoly0003s0088
| [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 | 23.24 | 0.8370 |
| 19 |
Mapoly0007s0227
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02212] minichromosome maintenance protein 4 (cell division control protein 54); [KOG0478] DNA replication licensing factor, MCM4 component; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain | 23.24 | 0.8441 |
| 20 |
Mapoly0177s0008
| [GO:0006260] DNA replication; [PF13191] AAA ATPase domain; [GO:0005634] nucleus; [KOG2543] Origin recognition complex, subunit 5; [PF14630] Origin recognition complex (ORC) subunit 5 C-terminus; [PTHR12705] ORIGIN RECOGNITION COMPLEX SUBUNIT 5; [GO:0000808] origin recognition complex; [K02607] origin recognition complex subunit 5 | 24.25 | 0.8377 |
| 21 |
Mapoly0007s0080
| [GO:0003677] DNA binding; [KOG1756] Histone 2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 | 24.45 | 0.8379 |
| 22 |
Mapoly0081s0019
| [PF00083] Sugar (and other) transporter; [GO:0016021] integral to membrane; [GO:0055085] transmembrane transport; [KOG0255] Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily); [PTHR24064] FAMILY NOT NAMED; [GO:0022857] transmembrane transporter activity | 25.81 | 0.6753 |
| 23 |
Mapoly0112s0022
| [PTHR19932] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; [GO:0005515] protein binding; [KOG1274] WD40 repeat protein; [K11274] chromosome transmission fidelity protein 4; [PTHR19932:SF10] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN 1; [PF00400] WD domain, G-beta repeat; [PF12341] Protein of unknown function (DUF3639) | 26.38 | 0.8387 |
| 24 |
Mapoly0068s0001
| [K10736] minichromosome maintenance protein 10; [GO:0006260] DNA replication; [PTHR13454] FAMILY NOT NAMED; [PF09329] Primase zinc finger; [GO:0005634] nucleus | 27.96 | 0.8299 |
| 25 |
Mapoly0028s0139
| [PTHR11200] INOSITOL 5-PHOSPHATASE; [PF03372] Endonuclease/Exonuclease/phosphatase family; [KOG0565] Inositol polyphosphate 5-phosphatase and related proteins | 29.05 | 0.6842 |
| 26 |
Mapoly0001s0011
| [K02219] cyclin-dependent kinase regulatory subunit CKS1; [KOG3484] Cyclin-dependent protein kinase CDC28, regulatory subunit CKS1, and related proteins; [PF01111] Cyclin-dependent kinase regulatory subunit; [GO:0016538] cyclin-dependent protein serine/threonine kinase regulator activity; [GO:0007049] cell cycle; [PTHR23415] CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 | 32.79 | 0.7951 |
| 27 |
Mapoly0035s0099
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02321] DNA polymerase alpha subunit B; [PTHR23061:SF12] SUBFAMILY NOT NAMED; [KOG1625] DNA polymerase alpha-primase complex, polymerase-associated subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [PTHR23061] DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; [GO:0003887] DNA-directed DNA polymerase activity; [PF08418] DNA polymerase alpha subunit B N-terminal | 35.24 | 0.8326 |
| 28 |
Mapoly0014s0033
| [KOG4285] Mitotic phosphoprotein; [PTHR21527] FAMILY NOT NAMED; [K14313] nuclear pore complex protein Nup53; [PF05172] Nup53/35/40-type RNA recognition motif | 35.71 | 0.7606 |
| 29 |
Mapoly0013s0016
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR31614] FAMILY NOT NAMED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08661] Replication factor A protein 3; [GO:0006310] DNA recombination | 37.23 | 0.7952 |
| 30 |
Mapoly0001s0105
| [K02541] minichromosome maintenance protein 3; [KOG0479] DNA replication licensing factor, MCM3 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11630:SF46] DNA REPLICATION LICENSING FACTOR MCM3; [PF00493] MCM2/3/5 family; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain | 38.01 | 0.8337 |
| 31 |
Mapoly0061s0010
| [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10536] DNA PRIMASE SMALL SUBUNIT; [KOG2851] Eukaryotic-type DNA primase, catalytic (small) subunit; [K02684] DNA primase small subunit [EC:2.7.7.-]; [2.7.7.-] Nucleotidyltransferases.; [PF01896] Eukaryotic and archaeal DNA primase small subunit | 38.83 | 0.8181 |
| 32 |
Mapoly0045s0042
| [KOG2475] CDC45 (cell division cycle 45)-like protein; [GO:0006270] DNA replication initiation; [PF02724] CDC45-like protein; [PTHR10507:SF0] CDC45-RELATED PROTEIN; [PTHR10507] CDC45-RELATED PROTEIN; [K06628] cell division control protein 45 | 38.99 | 0.8318 |
| 33 |
Mapoly0098s0032
| [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [PF11721] Di-glucose binding within endoplasmic reticulum; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity | 41.16 | 0.8313 |
| 34 |
Mapoly0004s0096
| [K11548] kinetochore protein Nuf2; [GO:0007067] mitosis; [PTHR21650] MEMBRALIN/KINETOCHORE PROTEIN NUF2; [PF03800] Nuf2 family; [KOG4438] Centromere-associated protein NUF2; [GO:0000775] chromosome, centromeric region; [PTHR21650:SF2] KINETOCHORE PROTEIN NUF2 | 43.23 | 0.8314 |
| 35 |
Mapoly0019s0059
| [PTHR31398:SF0] SUBFAMILY NOT NAMED; [PTHR31398] FAMILY NOT NAMED; [PF03962] Mnd1 family; [KOG3433] Protein involved in meiotic recombination/predicted coiled-coil protein | 44.02 | 0.7986 |
| 36 |
Mapoly0214s0011
| [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B | 44.50 | 0.8140 |
| 37 |
Mapoly0011s0137
| [K03504] DNA polymerase delta subunit 3; [GO:0006260] DNA replication; [PTHR17598] FAMILY NOT NAMED; [PF09507] DNA polymerase subunit Cdc27; [GO:0005634] nucleus | 45.43 | 0.7872 |
| 38 |
Mapoly0075s0022
| [KOG0482] DNA replication licensing factor, MCM7 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [K02210] minichromosome maintenance protein 7 (cell division control protein 47); [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [PTHR11630:SF26] DNA REPLICATION LICENSING FACTOR MCM7 | 45.83 | 0.8171 |
| 39 |
Mapoly0042s0007
| [GO:0003677] DNA binding; [K02213] cell division control protein 6; [KOG2227] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase; [PF13401] AAA domain; [PF01429] Methyl-CpG binding domain; [GO:0005634] nucleus; [PF09079] CDC6, C terminal; [PTHR10763] CELL DIVISION CONTROL PROTEIN 6-RELATED | 46.43 | 0.7865 |
| 40 |
Mapoly0009s0056
| [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PF08311] Mad3/BUB1 homology region 1; [K02178] checkpoint serine/threonine-protein kinase [EC:2.7.11.1]; [KOG1166] Mitotic checkpoint serine/threonine protein kinase; [PTHR14030] MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 | 47.33 | 0.8106 |
| 41 |
Mapoly0034s0101
| - | 48.47 | 0.7590 |
| 42 |
Mapoly0133s0052
| [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K08851] TP53 regulating kinase [EC:2.7.11.1]; [PTHR12209] O-SIALOGLYCOPROTEIN ENDOPEPTIDASE; [GO:0006468] protein phosphorylation; [KOG3087] Serine/threonine protein kinase; [GO:0004674] protein serine/threonine kinase activity | 49.19 | 0.7929 |
| 43 |
Mapoly0035s0108
| [GO:0005524] ATP binding; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23074] AAA ATPASE; [KOG0740] AAA+-type ATPase; [PF09336] Vps4 C terminal oligomerisation domain; [PTHR23074:SF17] FIDGETIN LIKE-1 | 49.84 | 0.7737 |
| 44 |
Mapoly0154s0005
| [PTHR22852] LETHAL(2)DENTICLELESS PROTEIN (RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN); [KOG0265] U5 snRNP-specific protein-like factor and related proteins; [K11790] denticleless; [GO:0005515] protein binding; [PF00400] WD domain, G-beta repeat | 49.84 | 0.8179 |
| 45 |
Mapoly0011s0047
| [PTHR12972] DOWNSTREAM NEIGHBOR OF SON | 50.20 | 0.7710 |
| 46 |
Mapoly0010s0189
| [PF07160] Protein of unknown function (DUF1395); [KOG4832] Uncharacterized conserved protein | 51.17 | 0.6958 |
| 47 |
Mapoly0045s0075
| - | 51.38 | 0.7409 |
| 48 |
Mapoly0159s0029
| [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [PTHR12081:SF7] TRANSCRIPTION FACTOR E2F; [PTHR12081] TRANSCRIPTION FACTOR E2F | 51.38 | 0.7674 |
| 49 |
Mapoly0179s0001
| [PTHR10994] RETICULON; [PF02453] Reticulon; [KOG1792] Reticulon | 52.34 | 0.8106 |
| 50 |
Mapoly0005s0016
| - | 52.80 | 0.7738 |
