| 1 |
Mapoly0007s0227
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02212] minichromosome maintenance protein 4 (cell division control protein 54); [KOG0478] DNA replication licensing factor, MCM4 component; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain | 2.83 | 0.9244 |
| 2 |
Mapoly0075s0032
| [GO:0003677] DNA binding; [GO:0006275] regulation of DNA replication; [GO:0030337] DNA polymerase processivity factor activity; [PTHR11352] PROLIFERATING CELL NUCLEAR ANTIGEN; [PF00705] Proliferating cell nuclear antigen, N-terminal domain; [K04802] proliferating cell nuclear antigen; [KOG1636] DNA polymerase delta processivity factor (proliferating cell nuclear antigen); [PF02747] Proliferating cell nuclear antigen, C-terminal domain | 3.00 | 0.8957 |
| 3 |
Mapoly0119s0016
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [KOG0480] DNA replication licensing factor, MCM6 component; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630:SF43] DNA REPLICATION LICENSING FACTOR MCM6; [K02542] minichromosome maintenance protein 6; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain | 4.47 | 0.9214 |
| 4 |
Mapoly0002s0035
| - | 5.10 | 0.8801 |
| 5 |
Mapoly0001s0011
| [K02219] cyclin-dependent kinase regulatory subunit CKS1; [KOG3484] Cyclin-dependent protein kinase CDC28, regulatory subunit CKS1, and related proteins; [PF01111] Cyclin-dependent kinase regulatory subunit; [GO:0016538] cyclin-dependent protein serine/threonine kinase regulator activity; [GO:0007049] cell cycle; [PTHR23415] CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 | 6.00 | 0.8484 |
| 6 |
Mapoly0075s0022
| [KOG0482] DNA replication licensing factor, MCM7 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [K02210] minichromosome maintenance protein 7 (cell division control protein 47); [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [PTHR11630:SF26] DNA REPLICATION LICENSING FACTOR MCM7 | 6.00 | 0.9084 |
| 7 |
Mapoly0035s0099
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02321] DNA polymerase alpha subunit B; [PTHR23061:SF12] SUBFAMILY NOT NAMED; [KOG1625] DNA polymerase alpha-primase complex, polymerase-associated subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [PTHR23061] DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; [GO:0003887] DNA-directed DNA polymerase activity; [PF08418] DNA polymerase alpha subunit B N-terminal | 6.48 | 0.9154 |
| 8 |
Mapoly0006s0287
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02209] minichromosome maintenance protein 5 (cell division control protein 46); [PTHR11630:SF42] DNA REPLICATION LICENSING FACTOR MCM5; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain; [KOG0481] DNA replication licensing factor, MCM5 component | 7.75 | 0.9033 |
| 9 |
Mapoly0087s0074
| [GO:0005685] U1 snRNP; [PF06220] U1 zinc finger; [GO:0008270] zinc ion binding; [GO:0000398] mRNA splicing, via spliceosome; [KOG3454] U1 snRNP-specific protein C; [GO:0000387] spliceosomal snRNP assembly; [PTHR31148] FAMILY NOT NAMED | 7.75 | 0.8778 |
| 10 |
Mapoly0064s0110
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR13394] ORIGIN RECOGNITION COMPLEX SUBUNIT 6; [PF05460] Origin recognition complex subunit 6 (ORC6); [GO:0005664] nuclear origin of replication recognition complex; [K02608] origin recognition complex subunit 6; [PTHR13394:SF0] SUBFAMILY NOT NAMED; [KOG4557] Origin recognition complex, subunit 6 | 8.49 | 0.8962 |
| 11 |
Mapoly0133s0052
| [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K08851] TP53 regulating kinase [EC:2.7.11.1]; [PTHR12209] O-SIALOGLYCOPROTEIN ENDOPEPTIDASE; [GO:0006468] protein phosphorylation; [KOG3087] Serine/threonine protein kinase; [GO:0004674] protein serine/threonine kinase activity | 10.00 | 0.8625 |
| 12 |
Mapoly0005s0130
| [GO:0042393] histone binding; [PF02182] SAD/SRA domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF13923] Zinc finger, C3HC4 type (RING finger); [PTHR14140] E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED | 10.10 | 0.8337 |
| 13 |
Mapoly0001s0105
| [K02541] minichromosome maintenance protein 3; [KOG0479] DNA replication licensing factor, MCM3 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11630:SF46] DNA REPLICATION LICENSING FACTOR MCM3; [PF00493] MCM2/3/5 family; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain | 10.25 | 0.9064 |
| 14 |
Mapoly0013s0016
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR31614] FAMILY NOT NAMED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08661] Replication factor A protein 3; [GO:0006310] DNA recombination | 10.49 | 0.8611 |
| 15 |
Mapoly0003s0086
| [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 | 11.83 | 0.8796 |
| 16 |
Mapoly0038s0098
| [K03351] anaphase-promoting complex subunit 4; [PF12896] Anaphase-promoting complex, cyclosome, subunit 4; [KOG4640] Anaphase-promoting complex (APC), subunit 4; [GO:0030071] regulation of mitotic metaphase/anaphase transition; [PF12894] Anaphase-promoting complex subunit 4 WD40 domain; [PTHR13260] ANAPHASE PROMOTING COMPLEX SUBUNIT 4 (APC4) (CYCLOSOME SUBUNIT 4); [GO:0005680] anaphase-promoting complex; [GO:0031145] anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 12.17 | 0.8071 |
| 17 |
Mapoly0061s0010
| [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10536] DNA PRIMASE SMALL SUBUNIT; [KOG2851] Eukaryotic-type DNA primase, catalytic (small) subunit; [K02684] DNA primase small subunit [EC:2.7.7.-]; [2.7.7.-] Nucleotidyltransferases.; [PF01896] Eukaryotic and archaeal DNA primase small subunit | 12.85 | 0.8893 |
| 18 |
Mapoly0007s0080
| [GO:0003677] DNA binding; [KOG1756] Histone 2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 | 13.78 | 0.8930 |
| 19 |
Mapoly0103s0079
| [GO:0003677] DNA binding; [PTHR13763:SF0] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0005634] nucleus; [GO:0006281] DNA repair; [GO:0004842] ubiquitin-protein ligase activity; [KOG4362] Transcriptional regulator BRCA1; [PTHR13763] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; [PF13771] PHD-like zinc-binding domain | 14.00 | 0.8992 |
| 20 |
Mapoly0011s0137
| [K03504] DNA polymerase delta subunit 3; [GO:0006260] DNA replication; [PTHR17598] FAMILY NOT NAMED; [PF09507] DNA polymerase subunit Cdc27; [GO:0005634] nucleus | 15.30 | 0.8457 |
| 21 |
Mapoly0177s0008
| [GO:0006260] DNA replication; [PF13191] AAA ATPase domain; [GO:0005634] nucleus; [KOG2543] Origin recognition complex, subunit 5; [PF14630] Origin recognition complex (ORC) subunit 5 C-terminus; [PTHR12705] ORIGIN RECOGNITION COMPLEX SUBUNIT 5; [GO:0000808] origin recognition complex; [K02607] origin recognition complex subunit 5 | 15.87 | 0.8806 |
| 22 |
Mapoly0051s0086
| [PF05859] Mis12 protein; [GO:0007067] mitosis; [GO:0005634] nucleus; [GO:0000775] chromosome, centromeric region; [GO:0007049] cell cycle | 16.09 | 0.8461 |
| 23 |
Mapoly0001s0330
| [PTHR11210] RING BOX; [PF12861] Anaphase-promoting complex subunit 11 RING-H2 finger; [K03358] anaphase-promoting complex subunit 11; [GO:0004842] ubiquitin-protein ligase activity; [GO:0005680] anaphase-promoting complex | 17.75 | 0.8236 |
| 24 |
Mapoly0166s0018
| [K10739] replication factor A2; [KOG3108] Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit; [PF08784] Replication protein A C terminal; [PTHR13989] REPLICATION PROTEIN A-RELATED; [GO:0003676] nucleic acid binding; [PF01336] OB-fold nucleic acid binding domain | 18.33 | 0.8746 |
| 25 |
Mapoly0006s0250
| [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 | 18.97 | 0.8700 |
| 26 |
Mapoly0109s0044
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PF04057] Replication factor-A protein 1, N-terminal domain; [GO:0005634] nucleus; [KOG0851] Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins; [PF08646] Replication factor-A C terminal domain; [GO:0003676] nucleic acid binding; [K07466] replication factor A1; [PTHR23273] REPLICATION FACTOR A 1, RFA1; [PF01336] OB-fold nucleic acid binding domain | 19.44 | 0.8322 |
| 27 |
Mapoly0029s0136
| [PTHR21206:SF0] SUBFAMILY NOT NAMED; [PF05916] GINS complex protein; [KOG3176] Predicted alpha-helical protein, potentially involved in replication/repair; [PTHR21206] SLD5 PROTEIN; [K10735] GINS complex subunit 4 | 19.49 | 0.8458 |
| 28 |
Mapoly0133s0010
| [PF00692] dUTPase; [GO:0046080] dUTP metabolic process; [3.6.1.23] dUTP diphosphatase.; [GO:0016787] hydrolase activity; [PTHR11241] DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE; [K01520] dUTP pyrophosphatase [EC:3.6.1.23]; [KOG3370] dUTPase | 21.21 | 0.8547 |
| 29 |
Mapoly0123s0001
| [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 | 21.35 | 0.8669 |
| 30 |
Mapoly0037s0034
| [K10744] ribonuclease H2 subunit B; [PTHR13383] FAMILY NOT NAMED; [PF09468] Ydr279p protein family (RNase H2 complex component); [GO:0005634] nucleus | 22.20 | 0.8553 |
| 31 |
Mapoly0095s0052
| [PF08839] DNA replication factor CDT1 like | 22.25 | 0.8389 |
| 32 |
Mapoly0009s0056
| [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PF08311] Mad3/BUB1 homology region 1; [K02178] checkpoint serine/threonine-protein kinase [EC:2.7.11.1]; [KOG1166] Mitotic checkpoint serine/threonine protein kinase; [PTHR14030] MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 | 23.49 | 0.8605 |
| 33 |
Mapoly0005s0217
| [KOG3428] Small nuclear ribonucleoprotein SMD1 and related snRNPs; [K11087] small nuclear ribonucleoprotein D1; [PTHR23338] SMALL NUCLEAR RIBONUCLEOPROTEIN SM; [PF01423] LSM domain | 23.66 | 0.8487 |
| 34 |
Mapoly0005s0203
| [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PF00313] 'Cold-shock' DNA-binding domain; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [PTHR11544] COLD SHOCK DOMAIN CONTAINING PROTEINS; [K09250] cellular nucleic acid-binding protein; [GO:0003676] nucleic acid binding; [KOG3070] Predicted RNA-binding protein containing PIN domain and invovled in translation or RNA processing | 24.08 | 0.8303 |
| 35 |
Mapoly0030s0056
| [PF00134] Cyclin, N-terminal domain; [PTHR10177] CYCLINE; [PF02984] Cyclin, C-terminal domain; [GO:0005634] nucleus; [KOG0656] G1/S-specific cyclin D | 24.49 | 0.8434 |
| 36 |
Mapoly0002s0271
| - | 24.70 | 0.7667 |
| 37 |
Mapoly0028s0066
| [GO:0005524] ATP binding; [KOG1112] Ribonucleotide reductase, alpha subunit; [GO:0006260] DNA replication; [GO:0055114] oxidation-reduction process; [GO:0004748] ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; [PF00317] Ribonucleotide reductase, all-alpha domain; [PTHR11573] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN; [PTHR11573:SF6] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN; [PF02867] Ribonucleotide reductase, barrel domain; [1.17.4.1] Ribonucleoside-diphosphate reductase.; [K10807] ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]; [PF03477] ATP cone domain | 24.80 | 0.8408 |
| 38 |
Mapoly0036s0154
| [KOG2606] OTU (ovarian tumor)-like cysteine protease; [PTHR12419] OTU DOMAIN CONTAINING PROTEIN; [PTHR12419:SF10] gb def: ENSANGP00000019868 (Fragment); [PF02338] OTU-like cysteine protease | 25.40 | 0.8395 |
| 39 |
Mapoly0003s0088
| [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 | 25.50 | 0.8602 |
| 40 |
Mapoly0059s0079
| [KOG2014] SMT3/SUMO-activating complex, AOS1/RAD31 component; [PF00899] ThiF family; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [K10684] ubiquitin-like 1-activating enzyme E1 A [EC:6.3.2.19] | 25.69 | 0.8394 |
| 41 |
Mapoly0004s0096
| [K11548] kinetochore protein Nuf2; [GO:0007067] mitosis; [PTHR21650] MEMBRALIN/KINETOCHORE PROTEIN NUF2; [PF03800] Nuf2 family; [KOG4438] Centromere-associated protein NUF2; [GO:0000775] chromosome, centromeric region; [PTHR21650:SF2] KINETOCHORE PROTEIN NUF2 | 25.75 | 0.8714 |
| 42 |
Mapoly0112s0022
| [PTHR19932] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; [GO:0005515] protein binding; [KOG1274] WD40 repeat protein; [K11274] chromosome transmission fidelity protein 4; [PTHR19932:SF10] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN 1; [PF00400] WD domain, G-beta repeat; [PF12341] Protein of unknown function (DUF3639) | 25.92 | 0.8621 |
| 43 |
Mapoly0004s0058
| [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PTHR13215:SF4] SUBFAMILY NOT NAMED; [PF08766] DEK C terminal domain; [PF02229] Transcriptional Coactivator p15 (PC4); [KOG2712] Transcriptional coactivator; [PTHR13215] RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; [GO:0003713] transcription coactivator activity | 26.06 | 0.7825 |
| 44 |
Mapoly0010s0212
| [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 | 26.15 | 0.8311 |
| 45 |
Mapoly0005s0205
| [PF00226] DnaJ domain; [KOG0719] Molecular chaperone (DnaJ superfamily); [PTHR24078] DNAJ HOMOLOG SUBFAMILY C MEMBER | 26.70 | 0.8511 |
| 46 |
Mapoly0007s0014
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02540] minichromosome maintenance protein 2; [PF12619] Mini-chromosome maintenance protein 2; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PTHR11630:SF44] DNA REPLICATION LICENSING FACTOR MCM2; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [KOG0477] DNA replication licensing factor, MCM2 component | 27.28 | 0.8603 |
| 47 |
Mapoly0146s0045
| [GO:0003723] RNA binding; [PTHR11207:SF1] RIBONUCLEASE III; [PF00035] Double-stranded RNA binding motif; [GO:0004525] ribonuclease III activity; [GO:0016075] rRNA catabolic process; [PTHR11207] RIBONUCLEASE III | 27.39 | 0.8347 |
| 48 |
Mapoly0092s0049
| [PTHR10501] U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B; [K11094] U2 small nuclear ribonucleoprotein B''; [GO:0000398] mRNA splicing, via spliceosome; [KOG4206] Spliceosomal protein snRNP-U1A/U2B; [GO:0003676] nucleic acid binding; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [GO:0017069] snRNA binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 29.22 | 0.8300 |
| 49 |
Mapoly0024s0061
| [KOG1508] DNA replication factor/protein phosphatase inhibitor SET/SPR-2; [PF00956] Nucleosome assembly protein (NAP); [GO:0005634] nucleus; [GO:0006334] nucleosome assembly; [K11290] template-activating factor I; [PTHR11875] TESTIS-SPECIFIC Y-ENCODED PROTEIN | 29.75 | 0.8303 |
| 50 |
Mapoly0053s0016
| [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B | 29.93 | 0.8501 |
