Guide Gene
- Gene ID
- Mapoly0123s0001
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0123s0001 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 0.00 1.0000 1 Mapoly0006s0250 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 1.00 0.9745 2 Mapoly0003s0086 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 2.45 0.9290 3 Mapoly0102s0037 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 2.83 0.9677 4 Mapoly0214s0011 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 3.87 0.9562 5 Mapoly0172s0017 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 4.00 0.9542 6 Mapoly0003s0088 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 4.47 0.9416 7 Mapoly0133s0010 [PF00692] dUTPase; [GO:0046080] dUTP metabolic process; [3.6.1.23] dUTP diphosphatase.; [GO:0016787] hydrolase activity; [PTHR11241] DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE; [K01520] dUTP pyrophosphatase [EC:3.6.1.23]; [KOG3370] dUTPase 4.47 0.9012 8 Mapoly0172s0018 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 6.00 0.9245 9 Mapoly0010s0212 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 6.16 0.8784 10 Mapoly0007s0080 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 6.93 0.9248 11 Mapoly0214s0010 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 7.48 0.9263 12 Mapoly0007s0226 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 9.38 0.8985 13 Mapoly0038s0109 [PTHR11842] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2; [GO:0007094] mitotic spindle assembly checkpoint; [PF02301] HORMA domain; [K02537] mitotic spindle assembly checkpoint protein MAD2; [PTHR11842:SF11] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A; [KOG3285] Spindle assembly checkpoint protein 10.95 0.8906 14 Mapoly0053s0016 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 13.67 0.8877 15 Mapoly0075s0022 [KOG0482] DNA replication licensing factor, MCM7 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [K02210] minichromosome maintenance protein 7 (cell division control protein 47); [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [PTHR11630:SF26] DNA REPLICATION LICENSING FACTOR MCM7 14.70 0.8955 16 Mapoly0030s0056 [PF00134] Cyclin, N-terminal domain; [PTHR10177] CYCLINE; [PF02984] Cyclin, C-terminal domain; [GO:0005634] nucleus; [KOG0656] G1/S-specific cyclin D 15.30 0.8556 17 Mapoly0007s0227 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02212] minichromosome maintenance protein 4 (cell division control protein 54); [KOG0478] DNA replication licensing factor, MCM4 component; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 16.31 0.8908 18 Mapoly0035s0099 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02321] DNA polymerase alpha subunit B; [PTHR23061:SF12] SUBFAMILY NOT NAMED; [KOG1625] DNA polymerase alpha-primase complex, polymerase-associated subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [PTHR23061] DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; [GO:0003887] DNA-directed DNA polymerase activity; [PF08418] DNA polymerase alpha subunit B N-terminal 17.29 0.8916 19 Mapoly0014s0182 - 18.76 0.8897 20 Mapoly0037s0134 - 20.00 0.7932 21 Mapoly0029s0121 [K11550] kinetochore protein Spc25, animal type; [PF08234] Chromosome segregation protein Spc25; [PTHR14281] FAMILY NOT NAMED 21.35 0.8669 22 Mapoly0177s0008 [GO:0006260] DNA replication; [PF13191] AAA ATPase domain; [GO:0005634] nucleus; [KOG2543] Origin recognition complex, subunit 5; [PF14630] Origin recognition complex (ORC) subunit 5 C-terminus; [PTHR12705] ORIGIN RECOGNITION COMPLEX SUBUNIT 5; [GO:0000808] origin recognition complex; [K02607] origin recognition complex subunit 5 22.36 0.8754 23 Mapoly0006s0287 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02209] minichromosome maintenance protein 5 (cell division control protein 46); [PTHR11630:SF42] DNA REPLICATION LICENSING FACTOR MCM5; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain; [KOG0481] DNA replication licensing factor, MCM5 component 22.91 0.8743 24 Mapoly0089s0025 - 23.83 0.7668 25 Mapoly0001s0501 [PF12681] Glyoxalase-like domain 26.72 0.8124 26 Mapoly0099s0055 [GO:0016020] membrane; [PTHR11654] OLIGOPEPTIDE TRANSPORTER-RELATED; [PF00854] POT family; [KOG1237] H+/oligopeptide symporter; [GO:0006810] transport; [GO:0005215] transporter activity 26.74 0.7767 27 Mapoly0042s0088 [PF03801] HEC/Ndc80p family; [K11547] kinetochore protein NDC80; [PTHR10643] KINETOCHORE PROTEIN NDC80; [KOG0995] Centromere-associated protein HEC1 26.83 0.8793 28 Mapoly0029s0136 [PTHR21206:SF0] SUBFAMILY NOT NAMED; [PF05916] GINS complex protein; [KOG3176] Predicted alpha-helical protein, potentially involved in replication/repair; [PTHR21206] SLD5 PROTEIN; [K10735] GINS complex subunit 4 28.14 0.8274 29 Mapoly0026s0138 [KOG0381] HMG box-containing protein; [PF00505] HMG (high mobility group) box; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN 29.29 0.8725 30 Mapoly0119s0016 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [KOG0480] DNA replication licensing factor, MCM6 component; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630:SF43] DNA REPLICATION LICENSING FACTOR MCM6; [K02542] minichromosome maintenance protein 6; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain 29.56 0.8722 31 Mapoly0002s0043 [GO:0003676] nucleic acid binding; [PF02037] SAP domain 29.98 0.8411 32 Mapoly0109s0044 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PF04057] Replication factor-A protein 1, N-terminal domain; [GO:0005634] nucleus; [KOG0851] Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins; [PF08646] Replication factor-A C terminal domain; [GO:0003676] nucleic acid binding; [K07466] replication factor A1; [PTHR23273] REPLICATION FACTOR A 1, RFA1; [PF01336] OB-fold nucleic acid binding domain 30.74 0.8014 33 Mapoly0041s0078 [GO:0045454] cell redox homeostasis; [5.3.4.1] Protein disulfide-isomerase.; [KOG0191] Thioredoxin/protein disulfide isomerase; [PTHR18929:SF38] PREDICTED: SIMILAR TO PROTEIN DISULFIDE ISOMERASE-ASSOCIATED 6; [K09584] protein disulfide-isomerase A6 [EC:5.3.4.1]; [PF00085] Thioredoxin; [PTHR18929] PROTEIN DISULFIDE ISOMERASE 32.25 0.7918 34 Mapoly0061s0010 [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10536] DNA PRIMASE SMALL SUBUNIT; [KOG2851] Eukaryotic-type DNA primase, catalytic (small) subunit; [K02684] DNA primase small subunit [EC:2.7.7.-]; [2.7.7.-] Nucleotidyltransferases.; [PF01896] Eukaryotic and archaeal DNA primase small subunit 32.76 0.8424 35 Mapoly0078s0017 - 37.75 0.8602 36 Mapoly0034s0111 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 38.95 0.8243 37 Mapoly0015s0092 [K00813] aspartate aminotransferase [EC:2.6.1.1]; [PTHR11879] ASPARTATE AMINOTRANSFERASE; [GO:0009058] biosynthetic process; [GO:0030170] pyridoxal phosphate binding; [KOG1411] Aspartate aminotransferase/Glutamic oxaloacetic transaminase AAT1/GOT2; [2.6.1.1] Aspartate transaminase.; [GO:0006520] cellular amino acid metabolic process; [PF00155] Aminotransferase class I and II; [GO:0008483] transaminase activity 39.19 0.7205 38 Mapoly0089s0046 [K06688] ubiquitin-conjugating enzyme E2 C [EC:6.3.2.19]; [PTHR24067:SF44] UBIQUITIN-CONJUGATING ENZYME E2 C; [PTHR24067] UBIQUITIN-CONJUGATING ENZYME E2; [GO:0016881] acid-amino acid ligase activity; [6.3.2.19] Ubiquitin--protein ligase.; [PF00179] Ubiquitin-conjugating enzyme; [KOG0421] Ubiquitin-protein ligase 39.24 0.7873 39 Mapoly0002s0035 - 39.38 0.8006 40 Mapoly0075s0032 [GO:0003677] DNA binding; [GO:0006275] regulation of DNA replication; [GO:0030337] DNA polymerase processivity factor activity; [PTHR11352] PROLIFERATING CELL NUCLEAR ANTIGEN; [PF00705] Proliferating cell nuclear antigen, N-terminal domain; [K04802] proliferating cell nuclear antigen; [KOG1636] DNA polymerase delta processivity factor (proliferating cell nuclear antigen); [PF02747] Proliferating cell nuclear antigen, C-terminal domain 40.12 0.8009 41 Mapoly0133s0052 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K08851] TP53 regulating kinase [EC:2.7.11.1]; [PTHR12209] O-SIALOGLYCOPROTEIN ENDOPEPTIDASE; [GO:0006468] protein phosphorylation; [KOG3087] Serine/threonine protein kinase; [GO:0004674] protein serine/threonine kinase activity 41.95 0.8029 42 Mapoly0001s0105 [K02541] minichromosome maintenance protein 3; [KOG0479] DNA replication licensing factor, MCM3 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11630:SF46] DNA REPLICATION LICENSING FACTOR MCM3; [PF00493] MCM2/3/5 family; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 42.21 0.8487 43 Mapoly0037s0034 [K10744] ribonuclease H2 subunit B; [PTHR13383] FAMILY NOT NAMED; [PF09468] Ydr279p protein family (RNase H2 complex component); [GO:0005634] nucleus 43.71 0.8195 44 Mapoly0005s0196 [PTHR24011] FAMILY NOT NAMED; [PF04059] RNA recognition motif 2; [GO:0003676] nucleic acid binding; [KOG4660] Protein Mei2, essential for commitment to meiosis, and related proteins; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 44.67 0.7863 45 Mapoly0005s0010 - 45.17 0.8371 46 Mapoly0071s0066 [PF04535] Domain of unknown function (DUF588); [PTHR11615] NITRATE, FROMATE, IRON DEHYDROGENASE 45.83 0.7434 47 Mapoly0103s0079 [GO:0003677] DNA binding; [PTHR13763:SF0] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0005634] nucleus; [GO:0006281] DNA repair; [GO:0004842] ubiquitin-protein ligase activity; [KOG4362] Transcriptional regulator BRCA1; [PTHR13763] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; [PF13771] PHD-like zinc-binding domain 46.73 0.8485 48 Mapoly0025s0128 [PF00134] Cyclin, N-terminal domain; [PTHR10177] CYCLINE; [PF02984] Cyclin, C-terminal domain; [GO:0005634] nucleus; [PTHR10177:SF49] CYCLIN-A; [KOG0654] G2/Mitotic-specific cyclin A; [K06627] cyclin A 46.99 0.8409 49 Mapoly0112s0022 [PTHR19932] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; [GO:0005515] protein binding; [KOG1274] WD40 repeat protein; [K11274] chromosome transmission fidelity protein 4; [PTHR19932:SF10] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN 1; [PF00400] WD domain, G-beta repeat; [PF12341] Protein of unknown function (DUF3639) 47.33 0.8347 50 Mapoly0166s0018 [K10739] replication factor A2; [KOG3108] Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit; [PF08784] Replication protein A C terminal; [PTHR13989] REPLICATION PROTEIN A-RELATED; [GO:0003676] nucleic acid binding; [PF01336] OB-fold nucleic acid binding domain 47.35 0.8243 51 Mapoly0001s0330 [PTHR11210] RING BOX; [PF12861] Anaphase-promoting complex subunit 11 RING-H2 finger; [K03358] anaphase-promoting complex subunit 11; [GO:0004842] ubiquitin-protein ligase activity; [GO:0005680] anaphase-promoting complex 47.37 0.7754 52 Mapoly0108s0043 - 47.37 0.8405 53 Mapoly0004s0096 [K11548] kinetochore protein Nuf2; [GO:0007067] mitosis; [PTHR21650] MEMBRALIN/KINETOCHORE PROTEIN NUF2; [PF03800] Nuf2 family; [KOG4438] Centromere-associated protein NUF2; [GO:0000775] chromosome, centromeric region; [PTHR21650:SF2] KINETOCHORE PROTEIN NUF2 48.06 0.8416 54 Mapoly0095s0052 [PF08839] DNA replication factor CDT1 like 49.50 0.7941 55 Mapoly0019s0185 [GO:0005506] iron ion binding; [KOG0156] Cytochrome P450 CYP2 subfamily; [GO:0055114] oxidation-reduction process; [GO:0016705] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; [GO:0020037] heme binding; [PTHR24298] FAMILY NOT NAMED; [PF00067] Cytochrome P450 50.40 0.7228 56 Mapoly0033s0039 [PF14368] Probable lipid transfer 50.50 0.7611 57 Mapoly0068s0100 [GO:0003872] 6-phosphofructokinase activity; [2.7.1.90] Diphosphate--fructose-6-phosphate 1-phosphotransferase.; [K00895] pyrophosphate--fructose-6-phosphate 1-phosphotransferase [EC:2.7.1.90]; [GO:0006096] glycolysis; [PF00365] Phosphofructokinase; [KOG2440] Pyrophosphate-dependent phosphofructo-1-kinase; [PTHR13697] PHOSPHOFRUCTOKINASE 50.91 0.7132 58 Mapoly0035s0038 [PTHR10774] EXTENDED SYNAPTOTAGMIN-RELATED; [PF00168] C2 domain; [GO:0005515] protein binding 51.58 0.7142 59 Mapoly0036s0153 [PTHR10971:SF5] MITOTIC CHECKPOINT PROTEIN BUB3; [PTHR10971] MRNA EXPORT FACTOR AND BUB3; [GO:0005515] protein binding; [K02180] cell cycle arrest protein BUB3; [KOG1036] Mitotic spindle checkpoint protein BUB3, WD repeat superfamily; [PF00400] WD domain, G-beta repeat 52.02 0.8129 60 Mapoly0007s0014 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02540] minichromosome maintenance protein 2; [PF12619] Mini-chromosome maintenance protein 2; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PTHR11630:SF44] DNA REPLICATION LICENSING FACTOR MCM2; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [KOG0477] DNA replication licensing factor, MCM2 component 54.04 0.8171 61 Mapoly0024s0069 [PF14520] Helix-hairpin-helix domain; [PTHR22942] RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER; [K04482] DNA repair protein RAD51; [PF08423] Rad51; [KOG1433] DNA repair protein RAD51/RHP55 54.26 0.7800 62 Mapoly0043s0009 [GO:0005840] ribosome; [GO:0006414] translational elongation; [PTHR21141] 60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER; [GO:0042254] ribosome biogenesis; [GO:0003735] structural constituent of ribosome; [PTHR21141:SF3] 60S ACIDIC RIBOSOMAL PROTEIN P0; [KOG0815] 60S acidic ribosomal protein P0; [GO:0005622] intracellular; [K02941] large subunit ribosomal protein LP0; [PF00466] Ribosomal protein L10; [PF00428] 60s Acidic ribosomal protein 54.41 0.7634 63 Mapoly0092s0049 [PTHR10501] U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B; [K11094] U2 small nuclear ribonucleoprotein B''; [GO:0000398] mRNA splicing, via spliceosome; [KOG4206] Spliceosomal protein snRNP-U1A/U2B; [GO:0003676] nucleic acid binding; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [GO:0017069] snRNA binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 56.68 0.7803 64 Mapoly0145s0029 - 57.24 0.7616 65 Mapoly0168s0010 [KOG1603] Copper chaperone; [GO:0030001] metal ion transport; [PTHR22814:SF15] COPPER TRANSPORT PROTEIN ATOX1 (METAL TRANSPORT PROTEIN ATX1); [PTHR22814] COPPER TRANSPORT PROTEIN ATOX1-RELATED; [PF00403] Heavy-metal-associated domain; [GO:0046872] metal ion binding 57.98 0.7631 66 Mapoly0077s0034 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 61.61 0.7100 67 Mapoly0014s0106 [KOG3172] Small nuclear ribonucleoprotein Sm D3; [PTHR23338] SMALL NUCLEAR RIBONUCLEOPROTEIN SM; [PF01423] LSM domain 61.92 0.7874 68 Mapoly0013s0048 [KOG0381] HMG box-containing protein; [PF00505] HMG (high mobility group) box; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN 62.35 0.7951 69 Mapoly0435s0001 [GO:0055114] oxidation-reduction process; [K00430] peroxidase [EC:1.11.1.7]; [PF00141] Peroxidase; [GO:0020037] heme binding; [PTHR31235] FAMILY NOT NAMED; [1.11.1.7] Peroxidase.; [GO:0006979] response to oxidative stress; [GO:0004601] peroxidase activity 62.35 0.7375 70 Mapoly0030s0151 [PF14368] Probable lipid transfer 62.40 0.7305 71 Mapoly0001s0558 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 64.06 0.7347 72 Mapoly0045s0075 - 65.50 0.7193 73 Mapoly0154s0005 [PTHR22852] LETHAL(2)DENTICLELESS PROTEIN (RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN); [KOG0265] U5 snRNP-specific protein-like factor and related proteins; [K11790] denticleless; [GO:0005515] protein binding; [PF00400] WD domain, G-beta repeat 65.90 0.8124 74 Mapoly0001s0011 [K02219] cyclin-dependent kinase regulatory subunit CKS1; [KOG3484] Cyclin-dependent protein kinase CDC28, regulatory subunit CKS1, and related proteins; [PF01111] Cyclin-dependent kinase regulatory subunit; [GO:0016538] cyclin-dependent protein serine/threonine kinase regulator activity; [GO:0007049] cell cycle; [PTHR23415] CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 67.56 0.7626 75 Mapoly0039s0047 [KOG0157] Cytochrome P450 CYP4/CYP19/CYP26 subfamilies; [GO:0005506] iron ion binding; [GO:0055114] oxidation-reduction process; [GO:0016705] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; [PTHR24296] FAMILY NOT NAMED; [GO:0020037] heme binding; [PF00067] Cytochrome P450 68.23 0.7501 76 Mapoly0057s0096 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 69.80 0.7312 77 Mapoly0004s0127 - 69.99 0.7807 78 Mapoly0025s0104 - 71.64 0.7825 79 Mapoly0087s0074 [GO:0005685] U1 snRNP; [PF06220] U1 zinc finger; [GO:0008270] zinc ion binding; [GO:0000398] mRNA splicing, via spliceosome; [KOG3454] U1 snRNP-specific protein C; [GO:0000387] spliceosomal snRNP assembly; [PTHR31148] FAMILY NOT NAMED 71.97 0.7677 80 Mapoly0009s0115 [PF03018] Dirigent-like protein; [PTHR21495] NUCLEOPORIN-RELATED 72.75 0.6852 81 Mapoly0055s0064 - 72.83 0.7919 82 Mapoly0042s0007 [GO:0003677] DNA binding; [K02213] cell division control protein 6; [KOG2227] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase; [PF13401] AAA domain; [PF01429] Methyl-CpG binding domain; [GO:0005634] nucleus; [PF09079] CDC6, C terminal; [PTHR10763] CELL DIVISION CONTROL PROTEIN 6-RELATED 74.88 0.7578 83 Mapoly0064s0110 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR13394] ORIGIN RECOGNITION COMPLEX SUBUNIT 6; [PF05460] Origin recognition complex subunit 6 (ORC6); [GO:0005664] nuclear origin of replication recognition complex; [K02608] origin recognition complex subunit 6; [PTHR13394:SF0] SUBFAMILY NOT NAMED; [KOG4557] Origin recognition complex, subunit 6 75.58 0.7869 84 Mapoly0098s0009 [K01104] protein-tyrosine phosphatase [EC:3.1.3.48]; [PF00581] Rhodanese-like domain; [PTHR10828:SF17] M-PHASE INDUCER PHOSPHATASE (DUAL SPECIFICITY PHOSPHATASE CDC25); [PTHR10828] M-PHASE INDUCER PHOSPHATASE (DUAL SPECIFICITY PHOSPHATASE CDC25); [3.1.3.48] Protein-tyrosine-phosphatase. 76.70 0.7880 85 Mapoly0051s0085 [KOG2267] Eukaryotic-type DNA primase, large subunit; [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10537] DNA PRIMASE LARGE SUBUNIT; [K02685] DNA primase large subunit [EC:2.7.7.-]; [PF04104] Eukaryotic and archaeal DNA primase, large subunit; [2.7.7.-] Nucleotidyltransferases. 77.03 0.7704 86 Mapoly0063s0098 [PF04770] ZF-HD protein dimerisation region; [PTHR31948] FAMILY NOT NAMED 77.92 0.7167 87 Mapoly0051s0086 [PF05859] Mis12 protein; [GO:0007067] mitosis; [GO:0005634] nucleus; [GO:0000775] chromosome, centromeric region; [GO:0007049] cell cycle 78.37 0.7656 88 Mapoly0009s0056 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PF08311] Mad3/BUB1 homology region 1; [K02178] checkpoint serine/threonine-protein kinase [EC:2.7.11.1]; [KOG1166] Mitotic checkpoint serine/threonine protein kinase; [PTHR14030] MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 78.99 0.7817 89 Mapoly0066s0004 [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [KOG0496] Beta-galactosidase; [GO:0005975] carbohydrate metabolic process; [PF02140] Galactose binding lectin domain; [GO:0030246] carbohydrate binding; [PTHR23421] BETA-GALACTOSIDASE RELATED; [PF01301] Glycosyl hydrolases family 35 81.41 0.7140 90 Mapoly0084s0025 [GO:0008565] protein transporter activity; [PTHR10527:SF1] IMPORTIN SUBUNIT BETA-1 (KARYOPHERIN SUBUNIT BETA-1); [GO:0006913] nucleocytoplasmic transport; [PTHR10527] IMPORTIN BETA 82.75 0.6756 91 Mapoly0130s0026 - 82.85 0.7641 92 Mapoly0050s0134 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PF01751] Toprim domain; [PTHR10169] DNA TOPOISOMERASE/GYRASE; [GO:0006265] DNA topological change; [GO:0003918] DNA topoisomerase type II (ATP-hydrolyzing) activity; [PF00521] DNA gyrase/topoisomerase IV, subunit A; [KOG0355] DNA topoisomerase type II; [5.99.1.3] DNA topoisomerase (ATP-hydrolyzing).; [PF00204] DNA gyrase B; [K03164] DNA topoisomerase II [EC:5.99.1.3] 83.43 0.7844 93 Mapoly0191s0002 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [K07374] tubulin alpha; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [KOG1376] Alpha tubulin; [GO:0005525] GTP binding 85.59 0.7444 94 Mapoly0060s0012 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [K11498] centromeric protein E; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 86.97 0.7814 95 Mapoly0152s0004 [PTHR12460] CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN; [PTHR12460:SF4] SUBFAMILY NOT NAMED; [PF04818] RNA polymerase II-binding domain.; [KOG2669] Regulator of nuclear mRNA 87.43 0.7467 96 Mapoly0189s0010 [PTHR15272:SF0] SUBFAMILY NOT NAMED; [PF12253] Chromatin assembly factor 1 subunit A; [PTHR15272] CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A (CAF-1 SUBUNIT A) 87.55 0.7400 97 Mapoly0040s0067 [GO:0016758] transferase activity, transferring hexosyl groups; [PF00201] UDP-glucoronosyl and UDP-glucosyl transferase; [PTHR11926] GLUCOSYL/GLUCURONOSYL TRANSFERASES; [GO:0008152] metabolic process; [KOG1192] UDP-glucuronosyl and UDP-glucosyl transferase 88.74 0.6920 98 Mapoly0059s0079 [KOG2014] SMT3/SUMO-activating complex, AOS1/RAD31 component; [PF00899] ThiF family; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [K10684] ubiquitin-like 1-activating enzyme E1 A [EC:6.3.2.19] 91.08 0.7639 99 Mapoly0125s0003 - 91.43 0.7579 100 Mapoly0062s0016 [PF04674] Phosphate-induced protein 1 conserved region; [PTHR31279] FAMILY NOT NAMED 91.78 0.6672 101 Mapoly0053s0030 [PTHR22768] UNCHARACTERIZED; [KOG1106] Uncharacterized conserved protein; [PF05916] GINS complex protein; [K10734] GINS complex subunit 3 92.47 0.7651 102 Mapoly0146s0045 [GO:0003723] RNA binding; [PTHR11207:SF1] RIBONUCLEASE III; [PF00035] Double-stranded RNA binding motif; [GO:0004525] ribonuclease III activity; [GO:0016075] rRNA catabolic process; [PTHR11207] RIBONUCLEASE III 94.47 0.7547 103 Mapoly0001s0495 [PF14368] Probable lipid transfer 95.62 0.6599 104 Mapoly0046s0055 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [KOG1374] Gamma tubulin; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [GO:0031122] cytoplasmic microtubule organization; [PTHR11588:SF7] TUBULIN GAMMA CHAIN; [K10389] tubulin gamma; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0007020] microtubule nucleation; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0000930] gamma-tubulin complex; [GO:0043234] protein complex; [GO:0005525] GTP binding 96.12 0.7276 105 Mapoly0170s0033 [PTHR11669] REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; [KOG2035] Replication factor C, subunit RFC3; [PF13177] DNA polymerase III, delta subunit; [PTHR11669:SF1] DNA POLYMERASE III SUBUNIT GAMMA/TAU; [PF08542] Replication factor C C-terminal domain; [K10756] replication factor C subunit 3/5 96.75 0.6823 106 Mapoly0036s0142 [GO:0003677] DNA binding; [KOG1757] Histone 2A; [K11251] histone H2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 97.28 0.7552 107 Mapoly0149s0014 [GO:0005737] cytoplasm; [GO:0003743] translation initiation factor activity; [GO:0005515] protein binding; [PTHR10410:SF3] EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT H; [PF01398] JAB1/Mov34/MPN/PAD-1 ubiquitin protease; [K03247] translation initiation factor eIF-3 subunit 3; [KOG1560] Translation initiation factor 3, subunit h (eIF-3h); [PTHR10410] EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED; [GO:0005852] eukaryotic translation initiation factor 3 complex 99.37 0.7242 108 Mapoly0005s0016 - 99.72 0.7308 109 Mapoly0022s0167 [PF12717] non-SMC mitotic condensation complex subunit 1; [PF12922] non-SMC mitotic condensation complex subunit 1, N-term; [GO:0007076] mitotic chromosome condensation; [PTHR14222] CONDENSIN; [KOG0414] Chromosome condensation complex Condensin, subunit D2; [K06677] condensin complex subunit 1 100.32 0.7713 110 Mapoly0012s0165 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 100.76 0.6753 111 Mapoly0179s0001 [PTHR10994] RETICULON; [PF02453] Reticulon; [KOG1792] Reticulon 102.88 0.7660 112 Mapoly0053s0099 [PF02225] PA domain; [GO:0004252] serine-type endopeptidase activity; [PF00082] Subtilase family; [PF05922] Peptidase inhibitor I9; [GO:0006508] proteolysis; [PTHR10795] PROPROTEIN CONVERTASE SUBTILISIN/KEXIN 103.20 0.6757 113 Mapoly0098s0043 [PF12717] non-SMC mitotic condensation complex subunit 1; [GO:0007076] mitotic chromosome condensation; [K11491] condensin-2 complex subunit D3; [PTHR14222:SF1] CONDENSIN; [PTHR14222] CONDENSIN 103.52 0.7646 114 Mapoly0028s0066 [GO:0005524] ATP binding; [KOG1112] Ribonucleotide reductase, alpha subunit; [GO:0006260] DNA replication; [GO:0055114] oxidation-reduction process; [GO:0004748] ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; [PF00317] Ribonucleotide reductase, all-alpha domain; [PTHR11573] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN; [PTHR11573:SF6] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN; [PF02867] Ribonucleotide reductase, barrel domain; [1.17.4.1] Ribonucleoside-diphosphate reductase.; [K10807] ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]; [PF03477] ATP cone domain 103.69 0.7488 115 Mapoly0023s0118 [PTHR12446] TESMIN/TSO1-RELATED; [PF03638] Tesmin/TSO1-like CXC domain, cysteine-rich domain 105.53 0.7585 116 Mapoly0013s0016 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR31614] FAMILY NOT NAMED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08661] Replication factor A protein 3; [GO:0006310] DNA recombination 105.92 0.7430 117 Mapoly0144s0003 - 106.44 0.7410 118 Mapoly0048s0068 [KOG0653] Cyclin B and related kinase-activating proteins; [PF00134] Cyclin, N-terminal domain; [PTHR10177] CYCLINE; [PF02984] Cyclin, C-terminal domain; [GO:0005634] nucleus; [K05868] cyclin B 106.47 0.7409 119 Mapoly0034s0119 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 108.28 0.7746 120 Mapoly0140s0032 [PTHR12748] ORIGIN RECOGNITION COMPLEX SUBUNIT 3; [PTHR12748:SF0] SUBFAMILY NOT NAMED; [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02605] origin recognition complex subunit 3; [PF07034] Origin recognition complex (ORC) subunit 3 N-terminus; [KOG2538] Origin recognition complex, subunit 3; [GO:0005664] nuclear origin of replication recognition complex; [PF02178] AT hook motif 108.66 0.7663 121 Mapoly0006s0009 [KOG4172] Predicted E3 ubiquitin ligase; [PF00097] Zinc finger, C3HC4 type (RING finger); [GO:0046872] metal ion binding; [PTHR23328] UNCHARACTERIZED 109.44 0.7385 122 Mapoly0038s0027 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PTHR10629:SF11] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF12047] Cytosine specific DNA methyltransferase replication foci domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 112.41 0.7190 123 Mapoly0069s0039 [GO:0016758] transferase activity, transferring hexosyl groups; [PF00201] UDP-glucoronosyl and UDP-glucosyl transferase; [PTHR11926] GLUCOSYL/GLUCURONOSYL TRANSFERASES; [GO:0008152] metabolic process; [KOG1192] UDP-glucuronosyl and UDP-glucosyl transferase 112.41 0.6342 124 Mapoly0045s0042 [KOG2475] CDC45 (cell division cycle 45)-like protein; [GO:0006270] DNA replication initiation; [PF02724] CDC45-like protein; [PTHR10507:SF0] CDC45-RELATED PROTEIN; [PTHR10507] CDC45-RELATED PROTEIN; [K06628] cell division control protein 45 112.77 0.7632 125 Mapoly0029s0119 - 114.03 0.6806 126 Mapoly0073s0027 [GO:0005524] ATP binding; [K07760] cyclin-dependent kinase [EC:2.7.11.22]; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [KOG0594] Protein kinase PCTAIRE and related kinases; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 114.86 0.7470 127 Mapoly0046s0032 [PTHR15486] ANCIENT UBIQUITOUS PROTEIN; [PF12710] haloacid dehalogenase-like hydrolase; [K13508] glycerol-3-phosphate acyltransferase [EC:2.3.1.15]; [PF01553] Acyltransferase; [GO:0016746] transferase activity, transferring acyl groups; [GO:0008152] metabolic process; [2.3.1.15] Glycerol-3-phosphate 1-O-acyltransferase. 116.34 0.6510 128 Mapoly0214s0009 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 118.43 0.6984 129 Mapoly0005s0205 [PF00226] DnaJ domain; [KOG0719] Molecular chaperone (DnaJ superfamily); [PTHR24078] DNAJ HOMOLOG SUBFAMILY C MEMBER 119.29 0.7532 130 Mapoly0056s0099 [GO:0016758] transferase activity, transferring hexosyl groups; [2.4.1.218] Hydroquinone glucosyltransferase.; [K08237] hydroquinone glucosyltransferase [EC:2.4.1.218]; [PF00201] UDP-glucoronosyl and UDP-glucosyl transferase; [PTHR11926] GLUCOSYL/GLUCURONOSYL TRANSFERASES; [GO:0008152] metabolic process; [KOG1192] UDP-glucuronosyl and UDP-glucosyl transferase 119.58 0.6537 131 Mapoly0190s0010 [GO:0008762] UDP-N-acetylmuramate dehydrogenase activity; [PTHR10801:SF0] 24-DEHYDROCHOLESTEROL REDUCTASE; [GO:0050660] flavin adenine dinucleotide binding; [KOG1262] FAD-binding protein DIMINUTO; [K09828] delta24-sterol reductase [EC:1.3.1.72]; [GO:0055114] oxidation-reduction process; [1.3.1.72] Delta(24)-sterol reductase.; [GO:0016491] oxidoreductase activity; [PTHR10801] 24-DEHYDROCHOLESTEROL REDUCTASE; [PF01565] FAD binding domain 119.74 0.6909 132 Mapoly0029s0041 [PF04515] Plasma-membrane choline transporter; [PTHR12385] CTL TRANSPORTER; [PTHR12385:SF4] CTL2-RELATED 120.40 0.6706 133 Mapoly0109s0054 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PF02229] Transcriptional Coactivator p15 (PC4); [KOG2712] Transcriptional coactivator; [PTHR13215] RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; [GO:0003713] transcription coactivator activity 121.75 0.7374 134 Mapoly0020s0099 [GO:0005840] ribosome; [K02949] small subunit ribosomal protein S11e; [KOG1728] 40S ribosomal protein S11; [GO:0003735] structural constituent of ribosome; [GO:0005622] intracellular; [PF00366] Ribosomal protein S17; [GO:0006412] translation; [PTHR10744] 40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER 125.45 0.7598 135 Mapoly0030s0020 [KOG2545] Conserved membrane protein; [PTHR13489:SF0] SUBFAMILY NOT NAMED; [PF13615] Putative alanine racemase; [PF09739] Mini-chromosome maintenance replisome factor; [PTHR13489] UNCHARACTERIZED 125.86 0.7577 136 Mapoly0003s0240 - 126.25 0.6601 137 Mapoly0002s0066 [GO:0006260] DNA replication; [GO:0005634] nucleus; [PF04081] DNA polymerase delta, subunit 4; [PTHR14303] DNA POLYMERASE DELTA SUBUNIT 4; [K03505] DNA polymerase delta subunit 4 126.60 0.6266 138 Mapoly0053s0008 - 127.00 0.7349 139 Mapoly0036s0151 [PF00268] Ribonucleotide reductase, small chain; [GO:0055114] oxidation-reduction process; [K10808] ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]; [PTHR23409] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN; [1.17.4.1] Ribonucleoside-diphosphate reductase.; [KOG1567] Ribonucleotide reductase, beta subunit; [GO:0009186] deoxyribonucleoside diphosphate metabolic process 128.81 0.7177 140 Mapoly0006s0093 [GO:0009058] biosynthetic process; [K00654] serine palmitoyltransferase [EC:2.3.1.50]; [GO:0030170] pyridoxal phosphate binding; [PTHR13693] CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE; [KOG1357] Serine palmitoyltransferase; [2.3.1.50] Serine C-palmitoyltransferase.; [PTHR13693:SF3] SERINE PALMITOYLTRANSFERASE 2; [PF00155] Aminotransferase class I and II 129.02 0.6481 141 Mapoly0005s0203 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PF00313] 'Cold-shock' DNA-binding domain; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [PTHR11544] COLD SHOCK DOMAIN CONTAINING PROTEINS; [K09250] cellular nucleic acid-binding protein; [GO:0003676] nucleic acid binding; [KOG3070] Predicted RNA-binding protein containing PIN domain and invovled in translation or RNA processing 131.54 0.7273 142 Mapoly0015s0086 [GO:0016020] membrane; [GO:0005524] ATP binding; [KOG0061] Transporter, ABC superfamily (Breast cancer resistance protein); [GO:0016887] ATPase activity; [PTHR19241] ATP-BINDING CASSETTE TRANSPORTER; [PF01061] ABC-2 type transporter; [PF00005] ABC transporter 132.05 0.6324 143 Mapoly0028s0075 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [K11251] histone H2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 132.21 0.7644 144 Mapoly0081s0071 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [PF00628] PHD-finger; [GO:0005515] protein binding; [PF12738] twin BRCT domain; [GO:0046872] metal ion binding 133.27 0.7378 145 Mapoly0010s0124 [K14320] aladin; [KOG2139] WD40 repeat protein; [GO:0005515] protein binding; [PTHR14494] ALADIN/ADRACALIN/AAAS; [PTHR14494:SF0] SUBFAMILY NOT NAMED; [PF00400] WD domain, G-beta repeat 135.53 0.6987 146 Mapoly0086s0078 [GO:0003677] DNA binding; [GO:0006275] regulation of DNA replication; [GO:0030337] DNA polymerase processivity factor activity; [PTHR11352] PROLIFERATING CELL NUCLEAR ANTIGEN; [PF00705] Proliferating cell nuclear antigen, N-terminal domain; [KOG1636] DNA polymerase delta processivity factor (proliferating cell nuclear antigen); [PF02747] Proliferating cell nuclear antigen, C-terminal domain 136.48 0.7155 147 Mapoly0001s0462 [PF13855] Leucine rich repeat; [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PTHR24420:SF474] SUBFAMILY NOT NAMED; [PF00069] Protein kinase domain; [PF08263] Leucine rich repeat N-terminal domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 138.91 0.6702 148 Mapoly0027s0041 [GO:0005643] nuclear pore; [PTHR13437] NUCLEOPORIN P58/P45 (NUCLEOPORIN-LIKE PROTEIN 1); [GO:0006913] nucleocytoplasmic transport 139.24 0.7191 149 Mapoly0006s0242 - 139.28 0.7260 150 Mapoly0037s0122 [PTHR12777] SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2; [KOG3459] Small nuclear ribonucleoprotein (snRNP) Sm core protein; [GO:0030532] small nuclear ribonucleoprotein complex; [K11096] small nuclear ribonucleoprotein D2; [PF01423] LSM domain; [GO:0008380] RNA splicing 139.53 0.7244 151 Mapoly0071s0013 [GO:0005840] ribosome; [GO:0003723] RNA binding; [PTHR13718] RIBOSOMAL S SUBUNIT; [PF00333] Ribosomal protein S5, N-terminal domain; [GO:0003735] structural constituent of ribosome; [KOG0877] 40S ribosomal protein S2/30S ribosomal protein S5; [GO:0006412] translation; [K02981] small subunit ribosomal protein S2e; [PF03719] Ribosomal protein S5, C-terminal domain 139.93 0.7372 152 Mapoly0098s0032 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [PF11721] Di-glucose binding within endoplasmic reticulum; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 141.06 0.7432 153 Mapoly0011s0083 [PTHR10997] IMPORTIN-7, 8, 11 141.81 0.7291 154 Mapoly0048s0048 [PTHR31802] FAMILY NOT NAMED 144.31 0.7168 155 Mapoly0053s0106 - 144.46 0.7351 156 Mapoly0071s0033 [GO:0016020] membrane; [GO:0005524] ATP binding; [KOG0061] Transporter, ABC superfamily (Breast cancer resistance protein); [GO:0016887] ATPase activity; [PTHR19241] ATP-BINDING CASSETTE TRANSPORTER; [PF01061] ABC-2 type transporter; [PF00005] ABC transporter 147.30 0.5995 157 Mapoly0158s0006 - 147.50 0.7096 158 Mapoly0073s0076 [KOG0409] Predicted dehydrogenase; [GO:0055114] oxidation-reduction process; [PF03446] NAD binding domain of 6-phosphogluconate dehydrogenase; [PTHR22981] 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED; [GO:0004616] phosphogluconate dehydrogenase (decarboxylating) activity; [GO:0051287] NAD binding; [GO:0006098] pentose-phosphate shunt; [PF14833] NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 147.70 0.6410 159 Mapoly0005s0217 [KOG3428] Small nuclear ribonucleoprotein SMD1 and related snRNPs; [K11087] small nuclear ribonucleoprotein D1; [PTHR23338] SMALL NUCLEAR RIBONUCLEOPROTEIN SM; [PF01423] LSM domain 148.21 0.7331 160 Mapoly0067s0089 [GO:0005515] protein binding; [PF00498] FHA domain; [PTHR23308] NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 150.18 0.7235 161 Mapoly0118s0024 [PTHR22840] FAMILY NOT NAMED; [GO:0005515] protein binding; [K14406] cleavage stimulation factor subunit 1; [KOG0640] mRNA cleavage stimulating factor complex; subunit 1; [PF00400] WD domain, G-beta repeat 151.22 0.6442 162 Mapoly0038s0098 [K03351] anaphase-promoting complex subunit 4; [PF12896] Anaphase-promoting complex, cyclosome, subunit 4; [KOG4640] Anaphase-promoting complex (APC), subunit 4; [GO:0030071] regulation of mitotic metaphase/anaphase transition; [PF12894] Anaphase-promoting complex subunit 4 WD40 domain; [PTHR13260] ANAPHASE PROMOTING COMPLEX SUBUNIT 4 (APC4) (CYCLOSOME SUBUNIT 4); [GO:0005680] anaphase-promoting complex; [GO:0031145] anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 151.49 0.6706 163 Mapoly0083s0082 [PTHR15840] CGI-121 FAMILY MEMBER; [KOG4066] Cell growth regulatory protein CGR11; [PF08617] Kinase binding protein CGI-121 152.94 0.6928 164 Mapoly0189s0011 [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain 155.02 0.7183 165 Mapoly0027s0013 [KOG4487] Uncharacterized conserved protein; [PF09696] Ctf8; [K11270] chromosome transmission fidelity protein 8 155.27 0.7249 166 Mapoly0002s0271 - 156.26 0.6706 167 Mapoly0051s0073 [PF14675] FANCI solenoid 1; [PTHR21818:SF0] SUBFAMILY NOT NAMED; [PF14680] FANCI helical domain 2; [KOG4553] Uncharacterized conserved protein; [K10895] fanconi anemia group I protein; [PF14679] FANCI helical domain 1; [GO:0006281] DNA repair; [PF14678] FANCI solenoid 4; [PTHR21818] BC025462 PROTEIN; [PF14676] FANCI solenoid 2 159.99 0.7134 168 Mapoly0120s0025 [PF01501] Glycosyl transferase family 8; [KOG1950] Glycosyl transferase, family 8 - glycogenin; [PTHR11183] GLYCOGENIN; [GO:0016757] transferase activity, transferring glycosyl groups 160.36 0.6439 169 Mapoly0052s0043 [K11098] small nuclear ribonucleoprotein F; [PTHR11021] SMALL NUCLEAR RIBONUCLEOPROTEIN F (SNRNP-F); [KOG3482] Small nuclear ribonucleoprotein (snRNP) SMF; [PF01423] LSM domain 161.94 0.7528 170 Mapoly0053s0014 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR15316] SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED; [PF01805] Surp module 162.31 0.6448 171 Mapoly0001s0419 [PTHR13789:SF4] MONOXYGENASE; [PF01494] FAD binding domain; [KOG2614] Kynurenine 3-monooxygenase and related flavoprotein monooxygenases; [PTHR13789] MONOOXYGENASE 162.79 0.6610 172 Mapoly0058s0078 [2.8.1.2] 3-mercaptopyruvate sulfurtransferase.; [PTHR11364:SF0] THIOSULFATE SULFURTRANSFERASE; [KOG1529] Mercaptopyruvate sulfurtransferase/thiosulfate sulfurtransferase; [PF00581] Rhodanese-like domain; [K01011] thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]; [PTHR11364] THIOSULFATE SULFERTANSFERASE; [2.8.1.1] Thiosulfate sulfurtransferase. 163.22 0.7092 173 Mapoly0065s0034 [GO:0000287] magnesium ion binding; [GO:0004743] pyruvate kinase activity; [GO:0006096] glycolysis; [GO:0030955] potassium ion binding; [PF02887] Pyruvate kinase, alpha/beta domain; [PF00224] Pyruvate kinase, barrel domain; [KOG2323] Pyruvate kinase; [PTHR11817] PYRUVATE KINASE 164.95 0.6954 174 Mapoly0006s0112 [K09613] COP9 signalosome complex subunit 5 [EC:3.4.-.-]; [GO:0005515] protein binding; [PTHR10410:SF6] COP9 SIGNALOSOME COMPLEX SUBUNIT 5; [PF01398] JAB1/Mov34/MPN/PAD-1 ubiquitin protease; [3.4.-.-] Acting on peptide bonds (peptide hydrolases).; [PTHR10410] EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED; [KOG1554] COP9 signalosome, subunit CSN5 166.00 0.6983 175 Mapoly0013s0165 [PTHR10804:SF13] METHIONINE AMINOPEPTIDASE 1; [K01265] methionyl aminopeptidase [EC:3.4.11.18]; [3.4.11.18] Methionyl aminopeptidase.; [KOG2738] Putative methionine aminopeptidase; [PF00557] Metallopeptidase family M24; [PTHR10804] PROTEASE FAMILY M24 (METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P) 167.31 0.7196 176 Mapoly0109s0002 [GO:0016758] transferase activity, transferring hexosyl groups; [K13496] UDP-glucosyl transferase 73C [EC:2.4.1.-]; [PF00201] UDP-glucoronosyl and UDP-glucosyl transferase; [PTHR11926] GLUCOSYL/GLUCURONOSYL TRANSFERASES; [GO:0008152] metabolic process; [2.4.1.-] Hexosyltransferases.; [KOG1192] UDP-glucuronosyl and UDP-glucosyl transferase 167.79 0.6090 177 Mapoly0118s0022 [PTHR31029] FAMILY NOT NAMED 168.48 0.6614 178 Mapoly0033s0031 [GO:0005524] ATP binding; [GO:0050515] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity; [PTHR20861] HOMOSERINE/4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE; [PF00288] GHMP kinases N terminal domain; [PTHR20861:SF2] 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE; [2.7.1.148] 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase.; [GO:0016114] terpenoid biosynthetic process; [K00919] 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148] 170.76 0.6642 179 Mapoly0030s0116 [GO:0055114] oxidation-reduction process; [GO:0005507] copper ion binding; [GO:0016491] oxidoreductase activity; [PF00394] Multicopper oxidase; [PTHR11709] MULTI-COPPER OXIDASE; [PTHR11709:SF2] SPORE COAT PROTEIN; [PF07731] Multicopper oxidase 172.92 0.5604 180 Mapoly0016s0148 - 172.93 0.5316 181 Mapoly0016s0083 [PF12214] Cell cycle regulated microtubule associated protein; [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [PTHR14326:SF9] TARGETING PROTEIN FOR XKLP2; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2) 173.61 0.7055 182 Mapoly0121s0031 [K00517] beta-carotene 15,15'-monooxygenase [EC:1.14.99.36]; [GO:0005506] iron ion binding; [1.14.-.-] Acting on paired donors, with incorporation or reduction of molecular oxygen.; [KOG0156] Cytochrome P450 CYP2 subfamily; [GO:0055114] oxidation-reduction process; [GO:0016705] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; [GO:0020037] heme binding; [PTHR24298] FAMILY NOT NAMED; [PF00067] Cytochrome P450 174.20 0.4960 183 Mapoly0003s0063 [GO:0005524] ATP binding; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24361:SF129] MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE; [GO:0006468] protein phosphorylation; [PTHR24361] MITOGEN-ACTIVATED KINASE KINASE KINASE 174.34 0.7089 184 Mapoly0022s0141 - 174.36 0.6798 185 Mapoly0003s0228 - 176.32 0.5972 186 Mapoly0107s0041 [KOG1303] Amino acid transporters; [PF01490] Transmembrane amino acid transporter protein; [PTHR22950] AMINO ACID TRANSPORTER 176.63 0.5064 187 Mapoly0010s0048 - 178.97 0.7037 188 Mapoly0085s0026 [PF00533] BRCA1 C Terminus (BRCT) domain; [PTHR23196] PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN 179.09 0.7059 189 Mapoly0078s0003 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR12029] RNA METHYLTRANSFERASE; [PF00588] SpoU rRNA Methylase family; [GO:0008173] RNA methyltransferase activity 180.18 0.7070 190 Mapoly0097s0065 [PTHR15350:SF2] COP9 SIGNALOSOME COMPLEX SUBUNIT 7; [GO:0005515] protein binding; [PF01399] PCI domain; [PTHR15350] COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17; [KOG2753] Uncharacterized conserved protein, contains PCI domain 180.96 0.6868 191 Mapoly0056s0086 - 182.25 0.5992 192 Mapoly0036s0154 [KOG2606] OTU (ovarian tumor)-like cysteine protease; [PTHR12419] OTU DOMAIN CONTAINING PROTEIN; [PTHR12419:SF10] gb def: ENSANGP00000019868 (Fragment); [PF02338] OTU-like cysteine protease 182.44 0.7022 193 Mapoly0159s0014 - 182.89 0.7348 194 Mapoly0011s0143 [PTHR15481:SF0] SUBFAMILY NOT NAMED; [K14325] RNA-binding protein with serine-rich domain 1; [PTHR15481] RIBONUCLEIC ACID BINDING PROTEIN S1; [GO:0003676] nucleic acid binding; [KOG0130] RNA-binding protein RBM8/Tsunagi (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 183.16 0.7019 195 Mapoly0002s0169 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [K06632] wee1-like protein kinase [EC:2.7.11.1]; [PTHR11042] EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE (EIF2-ALPHA KINASE)-RELATED; [KOG0601] Cyclin-dependent kinase WEE1 183.24 0.6990 196 Mapoly0105s0043 [GO:0003872] 6-phosphofructokinase activity; [2.7.1.90] Diphosphate--fructose-6-phosphate 1-phosphotransferase.; [K00895] pyrophosphate--fructose-6-phosphate 1-phosphotransferase [EC:2.7.1.90]; [GO:0006096] glycolysis; [PF00365] Phosphofructokinase; [KOG2440] Pyrophosphate-dependent phosphofructo-1-kinase; [PTHR13697] PHOSPHOFRUCTOKINASE; [PTHR13697:SF1] 6-PHOSPHOFRUCTOKINASE 183.30 0.5416 197 Mapoly0024s0061 [KOG1508] DNA replication factor/protein phosphatase inhibitor SET/SPR-2; [PF00956] Nucleosome assembly protein (NAP); [GO:0005634] nucleus; [GO:0006334] nucleosome assembly; [K11290] template-activating factor I; [PTHR11875] TESTIS-SPECIFIC Y-ENCODED PROTEIN 183.44 0.7004 198 Mapoly0005s0021 [PF13266] Protein of unknown function (DUF4057); [PTHR31132] FAMILY NOT NAMED 184.90 0.7190 199 Mapoly0027s0053 [PF14368] Probable lipid transfer 185.47 0.6755 200 Mapoly0039s0081 - 186.68 0.6805