Guide Gene
- Gene ID
- Mapoly0035s0099
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02321] DNA polymerase alpha subunit B; [PTHR23061:SF12] SUBFAMILY NOT NAMED; [KOG1625] DNA polymerase alpha-primase complex, polymerase-associated subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [PTHR23061] DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; [GO:0003887] DNA-directed DNA polymerase activity; [PF08418] DNA polymerase alpha subunit B N-terminal
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0035s0099 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02321] DNA polymerase alpha subunit B; [PTHR23061:SF12] SUBFAMILY NOT NAMED; [KOG1625] DNA polymerase alpha-primase complex, polymerase-associated subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [PTHR23061] DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; [GO:0003887] DNA-directed DNA polymerase activity; [PF08418] DNA polymerase alpha subunit B N-terminal 0.00 1.0000 1 Mapoly0103s0079 [GO:0003677] DNA binding; [PTHR13763:SF0] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0005634] nucleus; [GO:0006281] DNA repair; [GO:0004842] ubiquitin-protein ligase activity; [KOG4362] Transcriptional regulator BRCA1; [PTHR13763] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; [PF13771] PHD-like zinc-binding domain 1.73 0.9588 2 Mapoly0001s0105 [K02541] minichromosome maintenance protein 3; [KOG0479] DNA replication licensing factor, MCM3 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11630:SF46] DNA REPLICATION LICENSING FACTOR MCM3; [PF00493] MCM2/3/5 family; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 2.45 0.9572 3 Mapoly0177s0008 [GO:0006260] DNA replication; [PF13191] AAA ATPase domain; [GO:0005634] nucleus; [KOG2543] Origin recognition complex, subunit 5; [PF14630] Origin recognition complex (ORC) subunit 5 C-terminus; [PTHR12705] ORIGIN RECOGNITION COMPLEX SUBUNIT 5; [GO:0000808] origin recognition complex; [K02607] origin recognition complex subunit 5 2.45 0.9400 4 Mapoly0154s0005 [PTHR22852] LETHAL(2)DENTICLELESS PROTEIN (RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN); [KOG0265] U5 snRNP-specific protein-like factor and related proteins; [K11790] denticleless; [GO:0005515] protein binding; [PF00400] WD domain, G-beta repeat 3.16 0.9400 5 Mapoly0078s0017 - 3.74 0.9376 6 Mapoly0119s0016 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [KOG0480] DNA replication licensing factor, MCM6 component; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630:SF43] DNA REPLICATION LICENSING FACTOR MCM6; [K02542] minichromosome maintenance protein 6; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain 3.87 0.9527 7 Mapoly0007s0227 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02212] minichromosome maintenance protein 4 (cell division control protein 54); [KOG0478] DNA replication licensing factor, MCM4 component; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 4.00 0.9512 8 Mapoly0004s0096 [K11548] kinetochore protein Nuf2; [GO:0007067] mitosis; [PTHR21650] MEMBRALIN/KINETOCHORE PROTEIN NUF2; [PF03800] Nuf2 family; [KOG4438] Centromere-associated protein NUF2; [GO:0000775] chromosome, centromeric region; [PTHR21650:SF2] KINETOCHORE PROTEIN NUF2 4.90 0.9367 9 Mapoly0064s0110 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR13394] ORIGIN RECOGNITION COMPLEX SUBUNIT 6; [PF05460] Origin recognition complex subunit 6 (ORC6); [GO:0005664] nuclear origin of replication recognition complex; [K02608] origin recognition complex subunit 6; [PTHR13394:SF0] SUBFAMILY NOT NAMED; [KOG4557] Origin recognition complex, subunit 6 5.74 0.9310 10 Mapoly0166s0018 [K10739] replication factor A2; [KOG3108] Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit; [PF08784] Replication protein A C terminal; [PTHR13989] REPLICATION PROTEIN A-RELATED; [GO:0003676] nucleic acid binding; [PF01336] OB-fold nucleic acid binding domain 6.00 0.9066 11 Mapoly0029s0121 [K11550] kinetochore protein Spc25, animal type; [PF08234] Chromosome segregation protein Spc25; [PTHR14281] FAMILY NOT NAMED 6.48 0.9154 12 Mapoly0075s0022 [KOG0482] DNA replication licensing factor, MCM7 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [K02210] minichromosome maintenance protein 7 (cell division control protein 47); [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [PTHR11630:SF26] DNA REPLICATION LICENSING FACTOR MCM7 6.71 0.9330 13 Mapoly0061s0010 [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10536] DNA PRIMASE SMALL SUBUNIT; [KOG2851] Eukaryotic-type DNA primase, catalytic (small) subunit; [K02684] DNA primase small subunit [EC:2.7.7.-]; [2.7.7.-] Nucleotidyltransferases.; [PF01896] Eukaryotic and archaeal DNA primase small subunit 7.14 0.9086 14 Mapoly0006s0287 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02209] minichromosome maintenance protein 5 (cell division control protein 46); [PTHR11630:SF42] DNA REPLICATION LICENSING FACTOR MCM5; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain; [KOG0481] DNA replication licensing factor, MCM5 component 7.75 0.9321 15 Mapoly0042s0088 [PF03801] HEC/Ndc80p family; [K11547] kinetochore protein NDC80; [PTHR10643] KINETOCHORE PROTEIN NDC80; [KOG0995] Centromere-associated protein HEC1 9.17 0.9253 16 Mapoly0112s0022 [PTHR19932] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; [GO:0005515] protein binding; [KOG1274] WD40 repeat protein; [K11274] chromosome transmission fidelity protein 4; [PTHR19932:SF10] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN 1; [PF00400] WD domain, G-beta repeat; [PF12341] Protein of unknown function (DUF3639) 9.49 0.9145 17 Mapoly0028s0066 [GO:0005524] ATP binding; [KOG1112] Ribonucleotide reductase, alpha subunit; [GO:0006260] DNA replication; [GO:0055114] oxidation-reduction process; [GO:0004748] ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; [PF00317] Ribonucleotide reductase, all-alpha domain; [PTHR11573] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN; [PTHR11573:SF6] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN; [PF02867] Ribonucleotide reductase, barrel domain; [1.17.4.1] Ribonucleoside-diphosphate reductase.; [K10807] ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]; [PF03477] ATP cone domain 9.64 0.8773 18 Mapoly0007s0080 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 10.20 0.9200 19 Mapoly0055s0064 - 10.68 0.9059 20 Mapoly0140s0032 [PTHR12748] ORIGIN RECOGNITION COMPLEX SUBUNIT 3; [PTHR12748:SF0] SUBFAMILY NOT NAMED; [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02605] origin recognition complex subunit 3; [PF07034] Origin recognition complex (ORC) subunit 3 N-terminus; [KOG2538] Origin recognition complex, subunit 3; [GO:0005664] nuclear origin of replication recognition complex; [PF02178] AT hook motif 11.83 0.9054 21 Mapoly0045s0042 [KOG2475] CDC45 (cell division cycle 45)-like protein; [GO:0006270] DNA replication initiation; [PF02724] CDC45-like protein; [PTHR10507:SF0] CDC45-RELATED PROTEIN; [PTHR10507] CDC45-RELATED PROTEIN; [K06628] cell division control protein 45 12.00 0.9104 22 Mapoly0109s0044 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PF04057] Replication factor-A protein 1, N-terminal domain; [GO:0005634] nucleus; [KOG0851] Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins; [PF08646] Replication factor-A C terminal domain; [GO:0003676] nucleic acid binding; [K07466] replication factor A1; [PTHR23273] REPLICATION FACTOR A 1, RFA1; [PF01336] OB-fold nucleic acid binding domain 15.49 0.8401 23 Mapoly0036s0151 [PF00268] Ribonucleotide reductase, small chain; [GO:0055114] oxidation-reduction process; [K10808] ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]; [PTHR23409] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN; [1.17.4.1] Ribonucleoside-diphosphate reductase.; [KOG1567] Ribonucleotide reductase, beta subunit; [GO:0009186] deoxyribonucleoside diphosphate metabolic process 15.87 0.8368 24 Mapoly0189s0010 [PTHR15272:SF0] SUBFAMILY NOT NAMED; [PF12253] Chromatin assembly factor 1 subunit A; [PTHR15272] CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A (CAF-1 SUBUNIT A) 16.58 0.8433 25 Mapoly0002s0035 - 16.61 0.8543 26 Mapoly0007s0014 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02540] minichromosome maintenance protein 2; [PF12619] Mini-chromosome maintenance protein 2; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PTHR11630:SF44] DNA REPLICATION LICENSING FACTOR MCM2; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [KOG0477] DNA replication licensing factor, MCM2 component 16.97 0.8911 27 Mapoly0123s0001 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 17.29 0.8916 28 Mapoly0006s0250 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 17.32 0.8898 29 Mapoly0214s0011 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 18.33 0.9022 30 Mapoly0053s0016 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 19.75 0.8774 31 Mapoly0010s0212 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 19.90 0.8339 32 Mapoly0172s0018 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 20.49 0.8710 33 Mapoly0003s0088 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 21.02 0.8873 34 Mapoly0023s0118 [PTHR12446] TESMIN/TSO1-RELATED; [PF03638] Tesmin/TSO1-like CXC domain, cysteine-rich domain 22.45 0.8791 35 Mapoly0030s0020 [KOG2545] Conserved membrane protein; [PTHR13489:SF0] SUBFAMILY NOT NAMED; [PF13615] Putative alanine racemase; [PF09739] Mini-chromosome maintenance replisome factor; [PTHR13489] UNCHARACTERIZED 22.65 0.8825 36 Mapoly0037s0034 [K10744] ribonuclease H2 subunit B; [PTHR13383] FAMILY NOT NAMED; [PF09468] Ydr279p protein family (RNase H2 complex component); [GO:0005634] nucleus 24.25 0.8656 37 Mapoly0102s0037 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 24.68 0.8788 38 Mapoly0097s0064 [PTHR13710:SF1] ROTHMUND-THOMSON SYNDROME DNA HELICASE RECQ4; [GO:0005524] ATP binding; [PF11719] DNA replication and checkpoint protein; [K10730] ATP-dependent DNA helicase Q4 [EC:3.6.4.12]; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [GO:0003676] nucleic acid binding; [PF02037] SAP domain 25.42 0.8696 39 Mapoly0030s0056 [PF00134] Cyclin, N-terminal domain; [PTHR10177] CYCLINE; [PF02984] Cyclin, C-terminal domain; [GO:0005634] nucleus; [KOG0656] G1/S-specific cyclin D 26.50 0.8458 40 Mapoly0098s0009 [K01104] protein-tyrosine phosphatase [EC:3.1.3.48]; [PF00581] Rhodanese-like domain; [PTHR10828:SF17] M-PHASE INDUCER PHOSPHATASE (DUAL SPECIFICITY PHOSPHATASE CDC25); [PTHR10828] M-PHASE INDUCER PHOSPHATASE (DUAL SPECIFICITY PHOSPHATASE CDC25); [3.1.3.48] Protein-tyrosine-phosphatase. 26.51 0.8698 41 Mapoly0075s0032 [GO:0003677] DNA binding; [GO:0006275] regulation of DNA replication; [GO:0030337] DNA polymerase processivity factor activity; [PTHR11352] PROLIFERATING CELL NUCLEAR ANTIGEN; [PF00705] Proliferating cell nuclear antigen, N-terminal domain; [K04802] proliferating cell nuclear antigen; [KOG1636] DNA polymerase delta processivity factor (proliferating cell nuclear antigen); [PF02747] Proliferating cell nuclear antigen, C-terminal domain 27.95 0.8296 42 Mapoly0214s0010 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 29.29 0.8740 43 Mapoly0034s0119 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 30.03 0.8918 44 Mapoly0013s0016 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR31614] FAMILY NOT NAMED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08661] Replication factor A protein 3; [GO:0006310] DNA recombination 30.17 0.8313 45 Mapoly0072s0051 [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [KOG0597] Serine-threonine protein kinase FUSED; [GO:0006468] protein phosphorylation 30.46 0.8746 46 Mapoly0051s0073 [PF14675] FANCI solenoid 1; [PTHR21818:SF0] SUBFAMILY NOT NAMED; [PF14680] FANCI helical domain 2; [KOG4553] Uncharacterized conserved protein; [K10895] fanconi anemia group I protein; [PF14679] FANCI helical domain 1; [GO:0006281] DNA repair; [PF14678] FANCI solenoid 4; [PTHR21818] BC025462 PROTEIN; [PF14676] FANCI solenoid 2 30.51 0.8497 47 Mapoly0007s0226 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 32.91 0.8429 48 Mapoly0027s0041 [GO:0005643] nuclear pore; [PTHR13437] NUCLEOPORIN P58/P45 (NUCLEOPORIN-LIKE PROTEIN 1); [GO:0006913] nucleocytoplasmic transport 33.09 0.8284 49 Mapoly0098s0043 [PF12717] non-SMC mitotic condensation complex subunit 1; [GO:0007076] mitotic chromosome condensation; [K11491] condensin-2 complex subunit D3; [PTHR14222:SF1] CONDENSIN; [PTHR14222] CONDENSIN 33.59 0.8522 50 Mapoly0048s0048 [PTHR31802] FAMILY NOT NAMED 33.94 0.8291 51 Mapoly0038s0109 [PTHR11842] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2; [GO:0007094] mitotic spindle assembly checkpoint; [PF02301] HORMA domain; [K02537] mitotic spindle assembly checkpoint protein MAD2; [PTHR11842:SF11] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A; [KOG3285] Spindle assembly checkpoint protein 34.99 0.8479 52 Mapoly0051s0086 [PF05859] Mis12 protein; [GO:0007067] mitosis; [GO:0005634] nucleus; [GO:0000775] chromosome, centromeric region; [GO:0007049] cell cycle 35.24 0.8326 53 Mapoly0048s0021 - 35.61 0.6678 54 Mapoly0038s0027 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PTHR10629:SF11] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF12047] Cytosine specific DNA methyltransferase replication foci domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 36.06 0.8063 55 Mapoly0172s0017 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 36.06 0.8470 56 Mapoly0003s0086 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 36.40 0.8469 57 Mapoly0006s0112 [K09613] COP9 signalosome complex subunit 5 [EC:3.4.-.-]; [GO:0005515] protein binding; [PTHR10410:SF6] COP9 SIGNALOSOME COMPLEX SUBUNIT 5; [PF01398] JAB1/Mov34/MPN/PAD-1 ubiquitin protease; [3.4.-.-] Acting on peptide bonds (peptide hydrolases).; [PTHR10410] EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED; [KOG1554] COP9 signalosome, subunit CSN5 36.85 0.8070 58 Mapoly0009s0056 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PF08311] Mad3/BUB1 homology region 1; [K02178] checkpoint serine/threonine-protein kinase [EC:2.7.11.1]; [KOG1166] Mitotic checkpoint serine/threonine protein kinase; [PTHR14030] MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 37.31 0.8499 59 Mapoly0014s0182 - 37.52 0.8636 60 Mapoly0001s0446 - 37.56 0.8198 61 Mapoly0046s0055 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [KOG1374] Gamma tubulin; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [GO:0031122] cytoplasmic microtubule organization; [PTHR11588:SF7] TUBULIN GAMMA CHAIN; [K10389] tubulin gamma; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0007020] microtubule nucleation; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0000930] gamma-tubulin complex; [GO:0043234] protein complex; [GO:0005525] GTP binding 38.33 0.7992 62 Mapoly0026s0138 [KOG0381] HMG box-containing protein; [PF00505] HMG (high mobility group) box; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN 38.42 0.8709 63 Mapoly0108s0043 - 38.50 0.8687 64 Mapoly0060s0012 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [K11498] centromeric protein E; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 38.68 0.8717 65 Mapoly0068s0001 [K10736] minichromosome maintenance protein 10; [GO:0006260] DNA replication; [PTHR13454] FAMILY NOT NAMED; [PF09329] Primase zinc finger; [GO:0005634] nucleus 40.00 0.8366 66 Mapoly0095s0052 [PF08839] DNA replication factor CDT1 like 40.73 0.8227 67 Mapoly0010s0152 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PTHR13561:SF5] DNA REPLICATION REGULATOR DPB11; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 41.23 0.8493 68 Mapoly0001s0011 [K02219] cyclin-dependent kinase regulatory subunit CKS1; [KOG3484] Cyclin-dependent protein kinase CDC28, regulatory subunit CKS1, and related proteins; [PF01111] Cyclin-dependent kinase regulatory subunit; [GO:0016538] cyclin-dependent protein serine/threonine kinase regulator activity; [GO:0007049] cell cycle; [PTHR23415] CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 41.57 0.8022 69 Mapoly0098s0032 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [PF11721] Di-glucose binding within endoplasmic reticulum; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 42.47 0.8659 70 Mapoly0027s0013 [KOG4487] Uncharacterized conserved protein; [PF09696] Ctf8; [K11270] chromosome transmission fidelity protein 8 44.12 0.8414 71 Mapoly0005s0010 - 45.50 0.8550 72 Mapoly0043s0112 [PTHR21780] UNCHARACTERIZED; [KOG4670] Uncharacterized conserved membrane protein; [PTHR21780:SF0] SUBFAMILY NOT NAMED; [PF09786] Cytochrome B561, N terminal 46.30 0.8335 73 Mapoly0120s0004 [PF00488] MutS domain V; [GO:0005524] ATP binding; [K08735] DNA mismatch repair protein MSH2; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PTHR11361:SF35] MUTS HOMOLOG 2, MSH2; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III; [KOG0219] Mismatch repair ATPase MSH2 (MutS family); [PF05190] MutS family domain IV 46.77 0.8208 74 Mapoly0025s0128 [PF00134] Cyclin, N-terminal domain; [PTHR10177] CYCLINE; [PF02984] Cyclin, C-terminal domain; [GO:0005634] nucleus; [PTHR10177:SF49] CYCLIN-A; [KOG0654] G2/Mitotic-specific cyclin A; [K06627] cyclin A 46.83 0.8643 75 Mapoly0022s0167 [PF12717] non-SMC mitotic condensation complex subunit 1; [PF12922] non-SMC mitotic condensation complex subunit 1, N-term; [GO:0007076] mitotic chromosome condensation; [PTHR14222] CONDENSIN; [KOG0414] Chromosome condensation complex Condensin, subunit D2; [K06677] condensin complex subunit 1 47.33 0.8682 76 Mapoly0084s0025 [GO:0008565] protein transporter activity; [PTHR10527:SF1] IMPORTIN SUBUNIT BETA-1 (KARYOPHERIN SUBUNIT BETA-1); [GO:0006913] nucleocytoplasmic transport; [PTHR10527] IMPORTIN BETA 49.23 0.7237 77 Mapoly0024s0061 [KOG1508] DNA replication factor/protein phosphatase inhibitor SET/SPR-2; [PF00956] Nucleosome assembly protein (NAP); [GO:0005634] nucleus; [GO:0006334] nucleosome assembly; [K11290] template-activating factor I; [PTHR11875] TESTIS-SPECIFIC Y-ENCODED PROTEIN 49.92 0.8136 78 Mapoly0010s0124 [K14320] aladin; [KOG2139] WD40 repeat protein; [GO:0005515] protein binding; [PTHR14494] ALADIN/ADRACALIN/AAAS; [PTHR14494:SF0] SUBFAMILY NOT NAMED; [PF00400] WD domain, G-beta repeat 50.02 0.7782 79 Mapoly0190s0010 [GO:0008762] UDP-N-acetylmuramate dehydrogenase activity; [PTHR10801:SF0] 24-DEHYDROCHOLESTEROL REDUCTASE; [GO:0050660] flavin adenine dinucleotide binding; [KOG1262] FAD-binding protein DIMINUTO; [K09828] delta24-sterol reductase [EC:1.3.1.72]; [GO:0055114] oxidation-reduction process; [1.3.1.72] Delta(24)-sterol reductase.; [GO:0016491] oxidoreductase activity; [PTHR10801] 24-DEHYDROCHOLESTEROL REDUCTASE; [PF01565] FAD binding domain 50.28 0.7597 80 Mapoly0089s0046 [K06688] ubiquitin-conjugating enzyme E2 C [EC:6.3.2.19]; [PTHR24067:SF44] UBIQUITIN-CONJUGATING ENZYME E2 C; [PTHR24067] UBIQUITIN-CONJUGATING ENZYME E2; [GO:0016881] acid-amino acid ligase activity; [6.3.2.19] Ubiquitin--protein ligase.; [PF00179] Ubiquitin-conjugating enzyme; [KOG0421] Ubiquitin-protein ligase 50.73 0.7930 81 Mapoly0003s0120 [GO:0003677] DNA binding; [PTHR12708:SF0] SUBFAMILY NOT NAMED; [GO:0006260] DNA replication; [PF12213] DNA polymerases epsilon N terminal; [2.7.7.7] DNA-directed DNA polymerase.; [PTHR12708] DNA POLYMERASE EPSILON SUBUNIT B; [KOG3818] DNA polymerase epsilon, subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [GO:0003887] DNA-directed DNA polymerase activity; [K02325] DNA polymerase epsilon subunit 2 [EC:2.7.7.7] 51.93 0.8112 82 Mapoly0053s0106 - 53.44 0.8431 83 Mapoly0133s0052 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K08851] TP53 regulating kinase [EC:2.7.11.1]; [PTHR12209] O-SIALOGLYCOPROTEIN ENDOPEPTIDASE; [GO:0006468] protein phosphorylation; [KOG3087] Serine/threonine protein kinase; [GO:0004674] protein serine/threonine kinase activity 54.80 0.8121 84 Mapoly0145s0029 - 55.10 0.7836 85 Mapoly0080s0001 [GO:0005515] protein binding; [PTHR15271] CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; [KOG1009] Chromatin assembly complex 1 subunit B/CAC2 (contains WD40 repeats); [K10751] chromatin assembly factor 1 subunit B; [PF00400] WD domain, G-beta repeat 55.93 0.8332 86 Mapoly0002s0169 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [K06632] wee1-like protein kinase [EC:2.7.11.1]; [PTHR11042] EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE (EIF2-ALPHA KINASE)-RELATED; [KOG0601] Cyclin-dependent kinase WEE1 56.12 0.8135 87 Mapoly0035s0038 [PTHR10774] EXTENDED SYNAPTOTAGMIN-RELATED; [PF00168] C2 domain; [GO:0005515] protein binding 60.32 0.7175 88 Mapoly0065s0034 [GO:0000287] magnesium ion binding; [GO:0004743] pyruvate kinase activity; [GO:0006096] glycolysis; [GO:0030955] potassium ion binding; [PF02887] Pyruvate kinase, alpha/beta domain; [PF00224] Pyruvate kinase, barrel domain; [KOG2323] Pyruvate kinase; [PTHR11817] PYRUVATE KINASE 60.40 0.7988 89 Mapoly0146s0045 [GO:0003723] RNA binding; [PTHR11207:SF1] RIBONUCLEASE III; [PF00035] Double-stranded RNA binding motif; [GO:0004525] ribonuclease III activity; [GO:0016075] rRNA catabolic process; [PTHR11207] RIBONUCLEASE III 60.52 0.8003 90 Mapoly0027s0105 - 61.79 0.7494 91 Mapoly0189s0011 [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain 61.87 0.8150 92 Mapoly0029s0012 [GO:0005524] ATP binding; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [KOG0329] ATP-dependent RNA helicase; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding 62.08 0.8112 93 Mapoly0011s0202 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain 62.34 0.8415 94 Mapoly0101s0048 [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat 63.21 0.8161 95 Mapoly0081s0071 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [PF00628] PHD-finger; [GO:0005515] protein binding; [PF12738] twin BRCT domain; [GO:0046872] metal ion binding 63.47 0.8262 96 Mapoly0043s0009 [GO:0005840] ribosome; [GO:0006414] translational elongation; [PTHR21141] 60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER; [GO:0042254] ribosome biogenesis; [GO:0003735] structural constituent of ribosome; [PTHR21141:SF3] 60S ACIDIC RIBOSOMAL PROTEIN P0; [KOG0815] 60S acidic ribosomal protein P0; [GO:0005622] intracellular; [K02941] large subunit ribosomal protein LP0; [PF00466] Ribosomal protein L10; [PF00428] 60s Acidic ribosomal protein 65.02 0.7699 97 Mapoly0006s0242 - 65.99 0.8345 98 Mapoly0085s0026 [PF00533] BRCA1 C Terminus (BRCT) domain; [PTHR23196] PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN 66.27 0.8389 99 Mapoly0051s0085 [KOG2267] Eukaryotic-type DNA primase, large subunit; [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10537] DNA PRIMASE LARGE SUBUNIT; [K02685] DNA primase large subunit [EC:2.7.7.-]; [PF04104] Eukaryotic and archaeal DNA primase, large subunit; [2.7.7.-] Nucleotidyltransferases. 66.87 0.8035 100 Mapoly0024s0069 [PF14520] Helix-hairpin-helix domain; [PTHR22942] RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER; [K04482] DNA repair protein RAD51; [PF08423] Rad51; [KOG1433] DNA repair protein RAD51/RHP55 67.35 0.7890 101 Mapoly0185s0017 [GO:0030915] Smc5-Smc6 complex; [PF08746] RING-like domain; [KOG4718] Non-SMC (structural maintenance of chromosomes) element 1 protein (NSE1); [PTHR20973] NON-SMC ELEMENT 1-RELATED; [PF07574] Nse1 non-SMC component of SMC5-6 complex; [GO:0006281] DNA repair; [PTHR20973:SF0] SUBFAMILY NOT NAMED 68.67 0.7954 102 Mapoly0092s0049 [PTHR10501] U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B; [K11094] U2 small nuclear ribonucleoprotein B''; [GO:0000398] mRNA splicing, via spliceosome; [KOG4206] Spliceosomal protein snRNP-U1A/U2B; [GO:0003676] nucleic acid binding; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [GO:0017069] snRNA binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 69.28 0.7910 103 Mapoly0191s0002 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [K07374] tubulin alpha; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [KOG1376] Alpha tubulin; [GO:0005525] GTP binding 69.50 0.7785 104 Mapoly0125s0003 - 69.97 0.8070 105 Mapoly0149s0014 [GO:0005737] cytoplasm; [GO:0003743] translation initiation factor activity; [GO:0005515] protein binding; [PTHR10410:SF3] EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT H; [PF01398] JAB1/Mov34/MPN/PAD-1 ubiquitin protease; [K03247] translation initiation factor eIF-3 subunit 3; [KOG1560] Translation initiation factor 3, subunit h (eIF-3h); [PTHR10410] EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED; [GO:0005852] eukaryotic translation initiation factor 3 complex 70.20 0.7646 106 Mapoly0003s0042 [GO:0016597] amino acid binding; [PF02729] Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; [2.1.3.3] Ornithine carbamoyltransferase.; [GO:0016743] carboxyl- or carbamoyltransferase activity; [K00611] ornithine carbamoyltransferase [EC:2.1.3.3]; [GO:0006520] cellular amino acid metabolic process; [PTHR11405] CARBAMOYLTRANSFERASE RELATED; [KOG1504] Ornithine carbamoyltransferase OTC/ARG3; [PF00185] Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 70.40 0.6466 107 Mapoly0050s0134 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PF01751] Toprim domain; [PTHR10169] DNA TOPOISOMERASE/GYRASE; [GO:0006265] DNA topological change; [GO:0003918] DNA topoisomerase type II (ATP-hydrolyzing) activity; [PF00521] DNA gyrase/topoisomerase IV, subunit A; [KOG0355] DNA topoisomerase type II; [5.99.1.3] DNA topoisomerase (ATP-hydrolyzing).; [PF00204] DNA gyrase B; [K03164] DNA topoisomerase II [EC:5.99.1.3] 70.87 0.8381 108 Mapoly0053s0030 [PTHR22768] UNCHARACTERIZED; [KOG1106] Uncharacterized conserved protein; [PF05916] GINS complex protein; [K10734] GINS complex subunit 3 70.99 0.8214 109 Mapoly0133s0010 [PF00692] dUTPase; [GO:0046080] dUTP metabolic process; [3.6.1.23] dUTP diphosphatase.; [GO:0016787] hydrolase activity; [PTHR11241] DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE; [K01520] dUTP pyrophosphatase [EC:3.6.1.23]; [KOG3370] dUTPase 71.77 0.8061 110 Mapoly0007s0280 [GO:0005737] cytoplasm; [KOG3677] RNA polymerase I-associated factor - PAF67; [GO:0003743] translation initiation factor activity; [GO:0005852] eukaryotic translation initiation factor 3 complex; [PF10255] RNA polymerase I-associated factor PAF67; [PTHR13242] EUKARYOTIC TRANSLATION INITIATION FACTOR 3 72.11 0.6925 111 Mapoly0067s0089 [GO:0005515] protein binding; [PF00498] FHA domain; [PTHR23308] NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 72.46 0.8271 112 Mapoly0179s0001 [PTHR10994] RETICULON; [PF02453] Reticulon; [KOG1792] Reticulon 73.36 0.8230 113 Mapoly0029s0136 [PTHR21206:SF0] SUBFAMILY NOT NAMED; [PF05916] GINS complex protein; [KOG3176] Predicted alpha-helical protein, potentially involved in replication/repair; [PTHR21206] SLD5 PROTEIN; [K10735] GINS complex subunit 4 73.79 0.7903 114 Mapoly0087s0074 [GO:0005685] U1 snRNP; [PF06220] U1 zinc finger; [GO:0008270] zinc ion binding; [GO:0000398] mRNA splicing, via spliceosome; [KOG3454] U1 snRNP-specific protein C; [GO:0000387] spliceosomal snRNP assembly; [PTHR31148] FAMILY NOT NAMED 74.16 0.7891 115 Mapoly0029s0022 [PTHR23002] ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN; [PF06273] Plant specific eukaryotic initiation factor 4B; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding 74.28 0.7399 116 Mapoly0060s0031 - 74.67 0.7508 117 Mapoly0056s0099 [GO:0016758] transferase activity, transferring hexosyl groups; [2.4.1.218] Hydroquinone glucosyltransferase.; [K08237] hydroquinone glucosyltransferase [EC:2.4.1.218]; [PF00201] UDP-glucoronosyl and UDP-glucosyl transferase; [PTHR11926] GLUCOSYL/GLUCURONOSYL TRANSFERASES; [GO:0008152] metabolic process; [KOG1192] UDP-glucuronosyl and UDP-glucosyl transferase 75.23 0.6813 118 Mapoly0005s0016 - 75.37 0.7754 119 Mapoly0144s0003 - 77.95 0.7891 120 Mapoly0061s0044 [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2) 78.31 0.8163 121 Mapoly0034s0101 - 79.31 0.7453 122 Mapoly0001s0474 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [K11294] nucleolin; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 80.30 0.6982 123 Mapoly0019s0059 [PTHR31398:SF0] SUBFAMILY NOT NAMED; [PTHR31398] FAMILY NOT NAMED; [PF03962] Mnd1 family; [KOG3433] Protein involved in meiotic recombination/predicted coiled-coil protein 80.60 0.7946 124 Mapoly0005s0203 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PF00313] 'Cold-shock' DNA-binding domain; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [PTHR11544] COLD SHOCK DOMAIN CONTAINING PROTEINS; [K09250] cellular nucleic acid-binding protein; [GO:0003676] nucleic acid binding; [KOG3070] Predicted RNA-binding protein containing PIN domain and invovled in translation or RNA processing 80.73 0.7830 125 Mapoly0005s0130 [GO:0042393] histone binding; [PF02182] SAD/SRA domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF13923] Zinc finger, C3HC4 type (RING finger); [PTHR14140] E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED 80.94 0.7633 126 Mapoly0102s0001 [K06228] fused [EC:2.7.11.1]; [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR22983:SF6] MAPK KINASE 2-RELATED; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [KOG0598] Ribosomal protein S6 kinase and related proteins; [PF13646] HEAT repeats 81.24 0.8142 127 Mapoly0004s0127 - 81.33 0.8032 128 Mapoly0076s0033 [PF10444] Nbl1 / Borealin N terminal 81.90 0.8157 129 Mapoly0003s0063 [GO:0005524] ATP binding; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24361:SF129] MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE; [GO:0006468] protein phosphorylation; [PTHR24361] MITOGEN-ACTIVATED KINASE KINASE KINASE 82.51 0.8276 130 Mapoly0053s0099 [PF02225] PA domain; [GO:0004252] serine-type endopeptidase activity; [PF00082] Subtilase family; [PF05922] Peptidase inhibitor I9; [GO:0006508] proteolysis; [PTHR10795] PROPROTEIN CONVERTASE SUBTILISIN/KEXIN 82.81 0.6947 131 Mapoly0133s0013 [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10615] HISTONE ACETYLTRANSFERASE; [PF00856] SET domain 84.82 0.8020 132 Mapoly0043s0047 [GO:0005515] protein binding; [PF00612] IQ calmodulin-binding motif; [PTHR25069] FAMILY NOT NAMED; [PF00307] Calponin homology (CH) domain 84.95 0.8201 133 Mapoly0042s0105 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 87.38 0.8116 134 Mapoly0038s0098 [K03351] anaphase-promoting complex subunit 4; [PF12896] Anaphase-promoting complex, cyclosome, subunit 4; [KOG4640] Anaphase-promoting complex (APC), subunit 4; [GO:0030071] regulation of mitotic metaphase/anaphase transition; [PF12894] Anaphase-promoting complex subunit 4 WD40 domain; [PTHR13260] ANAPHASE PROMOTING COMPLEX SUBUNIT 4 (APC4) (CYCLOSOME SUBUNIT 4); [GO:0005680] anaphase-promoting complex; [GO:0031145] anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 88.05 0.7213 135 Mapoly0004s0203 [GO:0005507] copper ion binding; [GO:0009055] electron carrier activity; [PF02298] Plastocyanin-like domain 88.33 0.6790 136 Mapoly0026s0057 [PTHR23417] 3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE; [PF02390] Putative methyltransferase; [GO:0008176] tRNA (guanine-N7-)-methyltransferase activity; [K03439] tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]; [2.1.1.33] tRNA (guanine(46)-N(7))-methyltransferase.; [KOG3115] Methyltransferase-like protein; [GO:0006400] tRNA modification 88.77 0.7176 137 Mapoly0014s0028 [PTHR22942:SF8] DNA REPAIR PROTEIN RAD51 HOMOLOG 4 (R51H4); [KOG1434] Meiotic recombination protein Dmc1; [PTHR22942] RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER; [PF08423] Rad51 89.58 0.6645 138 Mapoly0005s0174 [GO:0005524] ATP binding; [KOG0933] Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E); [GO:0007076] mitotic chromosome condensation; [GO:0005515] protein binding; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0000796] condensin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PTHR18937:SF9] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC2; [K06674] structural maintenance of chromosome 2; [PF06470] SMC proteins Flexible Hinge Domain 89.92 0.8255 139 Mapoly0079s0005 [GO:0008080] N-acetyltransferase activity; [GO:0016568] chromatin modification; [PF00583] Acetyltransferase (GNAT) family; [GO:0005634] nucleus; [GO:0004402] histone acetyltransferase activity; [GO:0016573] histone acetylation; [KOG2696] Histone acetyltransferase type b catalytic subunit; [GO:0006348] chromatin silencing at telomere; [2.3.1.48] Histone acetyltransferase.; [PTHR12046] HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT; [K11303] histone acetyltransferase 1 [EC:2.3.1.48]; [PF10394] Histone acetyl transferase HAT1 N-terminus 91.45 0.7894 140 Mapoly0073s0027 [GO:0005524] ATP binding; [K07760] cyclin-dependent kinase [EC:2.7.11.22]; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [KOG0594] Protein kinase PCTAIRE and related kinases; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 91.90 0.8049 141 Mapoly0003s0057 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination 92.47 0.8075 142 Mapoly0011s0137 [K03504] DNA polymerase delta subunit 3; [GO:0006260] DNA replication; [PTHR17598] FAMILY NOT NAMED; [PF09507] DNA polymerase subunit Cdc27; [GO:0005634] nucleus 92.95 0.7741 143 Mapoly0006s0009 [KOG4172] Predicted E3 ubiquitin ligase; [PF00097] Zinc finger, C3HC4 type (RING finger); [GO:0046872] metal ion binding; [PTHR23328] UNCHARACTERIZED 93.30 0.7807 144 Mapoly0005s0125 [PF05383] La domain; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [PF08777] RNA binding motif; [K11090] lupus La protein; [KOG4213] RNA-binding protein La; [PTHR22792] LUPUS LA PROTEIN-RELATED 93.74 0.7458 145 Mapoly0122s0062 [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 94.24 0.8025 146 Mapoly0221s0003 - 95.46 0.7827 147 Mapoly0118s0005 [GO:0008233] peptidase activity; [3.4.22.49] Separase.; [K02365] separase [EC:3.4.22.49]; [GO:0005634] nucleus; [PF03568] Peptidase family C50; [GO:0006508] proteolysis; [PTHR12792] EXTRA SPINDLE POLES 1-RELATED 95.48 0.8027 148 Mapoly0016s0083 [PF12214] Cell cycle regulated microtubule associated protein; [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [PTHR14326:SF9] TARGETING PROTEIN FOR XKLP2; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2) 96.47 0.8064 149 Mapoly0053s0008 - 96.99 0.8000 150 Mapoly0001s0076 [PF00225] Kinesin motor domain; [GO:0007018] microtubule-based movement; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0008017] microtubule binding; [KOG4280] Kinesin-like protein; [PF06548] Kinesin-related; [GO:0003777] microtubule motor activity; [GO:0005871] kinesin complex 97.40 0.8049 151 Mapoly0002s0043 [GO:0003676] nucleic acid binding; [PF02037] SAP domain 99.95 0.7817 152 Mapoly0045s0075 - 102.41 0.7084 153 Mapoly0005s0196 [PTHR24011] FAMILY NOT NAMED; [PF04059] RNA recognition motif 2; [GO:0003676] nucleic acid binding; [KOG4660] Protein Mei2, essential for commitment to meiosis, and related proteins; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 103.42 0.7636 154 Mapoly0039s0099 [PF00169] PH domain; [PTHR12092] PLECKSTRIN 103.49 0.6733 155 Mapoly0025s0104 - 103.87 0.7876 156 Mapoly0043s0064 [PF10979] Protein of unknown function (DUF2786) 104.10 0.7882 157 Mapoly0109s0019 [KOG1375] Beta tubulin; [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [K07375] tubulin beta; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [GO:0005525] GTP binding 105.03 0.7250 158 Mapoly0209s0008 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF67] DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 106.16 0.8065 159 Mapoly0042s0007 [GO:0003677] DNA binding; [K02213] cell division control protein 6; [KOG2227] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase; [PF13401] AAA domain; [PF01429] Methyl-CpG binding domain; [GO:0005634] nucleus; [PF09079] CDC6, C terminal; [PTHR10763] CELL DIVISION CONTROL PROTEIN 6-RELATED 106.92 0.7548 160 Mapoly0001s0330 [PTHR11210] RING BOX; [PF12861] Anaphase-promoting complex subunit 11 RING-H2 finger; [K03358] anaphase-promoting complex subunit 11; [GO:0004842] ubiquitin-protein ligase activity; [GO:0005680] anaphase-promoting complex 107.04 0.7449 161 Mapoly0094s0016 [KOG4674] Uncharacterized conserved coiled-coil protein 108.63 0.7924 162 Mapoly0035s0108 [GO:0005524] ATP binding; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23074] AAA ATPASE; [KOG0740] AAA+-type ATPase; [PF09336] Vps4 C terminal oligomerisation domain; [PTHR23074:SF17] FIDGETIN LIKE-1 109.65 0.7490 163 Mapoly0109s0054 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PF02229] Transcriptional Coactivator p15 (PC4); [KOG2712] Transcriptional coactivator; [PTHR13215] RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; [GO:0003713] transcription coactivator activity 109.94 0.7652 164 Mapoly0047s0069 [GO:0005524] ATP binding; [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family; [KOG0358] Chaperonin complex component, TCP-1 delta subunit (CCT4) 110.51 0.7443 165 Mapoly0001s0257 - 111.24 0.6868 166 Mapoly0006s0290 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR10670:SF0] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A; [GO:0000166] nucleotide binding; [GO:0008270] zinc ion binding; [2.7.7.7] DNA-directed DNA polymerase.; [KOG1798] DNA polymerase epsilon, catalytic subunit A; [PF08490] Domain of unknown function (DUF1744); [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF00136] DNA polymerase family B; [GO:0008622] epsilon DNA polymerase complex; [K02324] DNA polymerase epsilon subunit 1 [EC:2.7.7.7]; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10670] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A 112.14 0.7875 167 Mapoly0065s0078 [PTHR24115:SF171] SUBFAMILY NOT NAMED; [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [K10403] kinesin family member 22; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 112.31 0.7915 168 Mapoly0113s0048 [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [KOG1408] WD40 repeat protein; [PF00400] WD domain, G-beta repeat 112.96 0.8004 169 Mapoly0025s0127 - 114.68 0.7805 170 Mapoly0042s0023 [GO:0005524] ATP binding; [2.7.12.1] Dual-specificity kinase.; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [K08866] serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]; [PTHR22974] MIXED LINEAGE PROTEIN KINASE 114.79 0.7895 171 Mapoly0158s0006 - 116.96 0.7697 172 Mapoly0001s0501 [PF12681] Glyoxalase-like domain 117.15 0.7338 173 Mapoly0014s0106 [KOG3172] Small nuclear ribonucleoprotein Sm D3; [PTHR23338] SMALL NUCLEAR RIBONUCLEOPROTEIN SM; [PF01423] LSM domain 118.11 0.7720 174 Mapoly0083s0034 - 119.15 0.7340 175 Mapoly0127s0019 - 120.64 0.7730 176 Mapoly0036s0111 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR12029] RNA METHYLTRANSFERASE; [PF00588] SpoU rRNA Methylase family; [GO:0008173] RNA methyltransferase activity; [KOG2506] SpoU rRNA Methylase family protein 121.05 0.6586 177 Mapoly0007s0003 [GO:0005515] protein binding; [PTHR19918:SF8] gb def: Meiosis-specific APC/C activator protein AMA1 (Activator of meiotic APC/C protei; [KOG0305] Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits; [K03363] cell division cycle 20, cofactor of APC complex; [PTHR19918] CELL DIVISION CYCLE 20 (CDC20) (FIZZY)-RELATED; [PF00400] WD domain, G-beta repeat 121.12 0.7510 178 Mapoly0034s0111 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 122.07 0.7724 179 Mapoly0037s0134 - 122.90 0.6904 180 Mapoly0056s0020 [PF04548] AIG1 family; [PTHR10903] GTPASE, IMAP FAMILY MEMBER-RELATED; [GO:0005525] GTP binding 124.82 0.7212 181 Mapoly0048s0068 [KOG0653] Cyclin B and related kinase-activating proteins; [PF00134] Cyclin, N-terminal domain; [PTHR10177] CYCLINE; [PF02984] Cyclin, C-terminal domain; [GO:0005634] nucleus; [K05868] cyclin B 124.83 0.7595 182 Mapoly0130s0026 - 125.36 0.7543 183 Mapoly0004s0300 [GO:0005524] ATP binding; [PTHR11909:SF7] CELL DIVISION CONTROL PROTEIN 7; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K02214] cell division control protein 7 [EC:2.7.11.1]; [KOG1167] Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination; [GO:0006468] protein phosphorylation; [PTHR11909] CASEIN KINASE-RELATED 125.48 0.7884 184 Mapoly0151s0030 [PF00557] Metallopeptidase family M24; [PTHR10804:SF11] PROLIFERATION-ASSOCIATED PROTEIN 2G4; [PTHR10804] PROTEASE FAMILY M24 (METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P); [KOG2776] Metallopeptidase 126.13 0.7335 185 Mapoly0089s0025 - 126.78 0.6797 186 Mapoly0116s0033 [GO:0005840] ribosome; [PTHR19431] 60S RIBOSOMAL PROTEIN L4; [K02930] large subunit ribosomal protein L4e; [KOG1475] Ribosomal protein RPL1/RPL2/RL4L4; [GO:0003735] structural constituent of ribosome; [PF00573] Ribosomal protein L4/L1 family; [GO:0006412] translation; [PF14374] 60S ribosomal protein L4 C-terminal domain 127.68 0.6189 187 Mapoly0032s0119 [GO:0007076] mitotic chromosome condensation; [K06678] condensin complex subunit 3; [GO:0000796] condensin complex; [PTHR14418] CONDENSIN COMPLEX SUBUNIT 3-RELATED; [PF12719] Nuclear condensing complex subunits, C-term domain 128.00 0.7889 188 Mapoly0013s0048 [KOG0381] HMG box-containing protein; [PF00505] HMG (high mobility group) box; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN 129.53 0.7756 189 Mapoly0084s0055 [GO:0005524] ATP binding; [KOG0744] AAA+-type ATPase; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23077] AAA-FAMILY ATPASE 129.73 0.7331 190 Mapoly0023s0062 [K11086] small nuclear ribonucleoprotein B and B'; [PTHR10701] SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N; [KOG3168] U1 snRNP component; [PF01423] LSM domain 129.92 0.7177 191 Mapoly0003s0259 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PTHR24420:SF474] SUBFAMILY NOT NAMED; [PF00069] Protein kinase domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 131.42 0.7614 192 Mapoly0007s0134 [KOG3000] Microtubule-binding protein involved in cell cycle control; [GO:0005515] protein binding; [PTHR10623:SF6] MICROTUBULE-ASSOCIATED PROTEIN EB1 (MICROTUBULE PLUS-END BINDING PROTEIN); [PF03271] EB1-like C-terminal motif; [GO:0008017] microtubule binding; [PTHR10623] MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER; [PF00307] Calponin homology (CH) domain 131.51 0.7326 193 Mapoly0080s0039 [PTHR15081] NUCLEAR AUTOANTIGENIC SPERM PROTEIN (NASP)-RELATED; [PF13414] TPR repeat; [PF10516] SHNi-TPR 132.00 0.7420 194 Mapoly0179s0014 [PTHR11586:SF1] SUBFAMILY NOT NAMED; [KOG2241] tRNA-binding protein; [PF01588] Putative tRNA binding domain; [GO:0000049] tRNA binding; [PTHR11586] FAMILY NOT NAMED 132.43 0.7115 195 Mapoly0016s0108 [GO:0005524] ATP binding; [K10755] replication factor C subunit 2/4; [KOG0991] Replication factor C, subunit RFC2; [PTHR11669] REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08542] Replication factor C C-terminal domain 133.99 0.7296 196 Mapoly0001s0188 - 134.92 0.7728 197 Mapoly0013s0011 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 136.06 0.7441 198 Mapoly0043s0090 [GO:0005524] ATP binding; [GO:0000166] nucleotide binding; [PTHR22594] ASPARTYL/LYSYL-TRNA SYNTHETASE; [6.1.1.22] Asparagine--tRNA ligase.; [KOG0554] Asparaginyl-tRNA synthetase (mitochondrial); [K01893] asparaginyl-tRNA synthetase [EC:6.1.1.22]; [GO:0003676] nucleic acid binding; [PF01336] OB-fold nucleic acid binding domain; [GO:0006418] tRNA aminoacylation for protein translation; [GO:0004812] aminoacyl-tRNA ligase activity; [PF00152] tRNA synthetases class II (D, K and N) 138.26 0.7050 199 Mapoly0060s0056 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 138.78 0.7379 200 Mapoly0030s0102 [PF08317] Spc7 kinetochore protein 139.39 0.7731