| 1 |
Mapoly0007s0227
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02212] minichromosome maintenance protein 4 (cell division control protein 54); [KOG0478] DNA replication licensing factor, MCM4 component; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain | 5.29 | 0.8818 |
| 2 |
Mapoly0001s0208
| [PTHR31431] FAMILY NOT NAMED; [KOG4833] Uncharacterized conserved protein; [K14311] nuclear pore complex protein Nup188; [PF10487] Nucleoporin subcomplex protein binding to Pom34 | 7.75 | 0.8592 |
| 3 |
Mapoly0119s0016
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [KOG0480] DNA replication licensing factor, MCM6 component; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630:SF43] DNA REPLICATION LICENSING FACTOR MCM6; [K02542] minichromosome maintenance protein 6; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain | 8.25 | 0.8786 |
| 4 |
Mapoly0011s0202
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain | 9.64 | 0.8780 |
| 5 |
Mapoly0061s0010
| [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10536] DNA PRIMASE SMALL SUBUNIT; [KOG2851] Eukaryotic-type DNA primase, catalytic (small) subunit; [K02684] DNA primase small subunit [EC:2.7.7.-]; [2.7.7.-] Nucleotidyltransferases.; [PF01896] Eukaryotic and archaeal DNA primase small subunit | 9.75 | 0.8734 |
| 6 |
Mapoly0122s0062
| [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 | 10.00 | 0.8679 |
| 7 |
Mapoly0112s0022
| [PTHR19932] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; [GO:0005515] protein binding; [KOG1274] WD40 repeat protein; [K11274] chromosome transmission fidelity protein 4; [PTHR19932:SF10] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN 1; [PF00400] WD domain, G-beta repeat; [PF12341] Protein of unknown function (DUF3639) | 10.20 | 0.8745 |
| 8 |
Mapoly0075s0022
| [KOG0482] DNA replication licensing factor, MCM7 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [K02210] minichromosome maintenance protein 7 (cell division control protein 47); [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [PTHR11630:SF26] DNA REPLICATION LICENSING FACTOR MCM7 | 14.49 | 0.8732 |
| 9 |
Mapoly0011s0137
| [K03504] DNA polymerase delta subunit 3; [GO:0006260] DNA replication; [PTHR17598] FAMILY NOT NAMED; [PF09507] DNA polymerase subunit Cdc27; [GO:0005634] nucleus | 15.17 | 0.8378 |
| 10 |
Mapoly0140s0032
| [PTHR12748] ORIGIN RECOGNITION COMPLEX SUBUNIT 3; [PTHR12748:SF0] SUBFAMILY NOT NAMED; [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02605] origin recognition complex subunit 3; [PF07034] Origin recognition complex (ORC) subunit 3 N-terminus; [KOG2538] Origin recognition complex, subunit 3; [GO:0005664] nuclear origin of replication recognition complex; [PF02178] AT hook motif | 16.25 | 0.8698 |
| 11 |
Mapoly0006s0287
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02209] minichromosome maintenance protein 5 (cell division control protein 46); [PTHR11630:SF42] DNA REPLICATION LICENSING FACTOR MCM5; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain; [KOG0481] DNA replication licensing factor, MCM5 component | 16.70 | 0.8689 |
| 12 |
Mapoly0006s0290
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR10670:SF0] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A; [GO:0000166] nucleotide binding; [GO:0008270] zinc ion binding; [2.7.7.7] DNA-directed DNA polymerase.; [KOG1798] DNA polymerase epsilon, catalytic subunit A; [PF08490] Domain of unknown function (DUF1744); [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF00136] DNA polymerase family B; [GO:0008622] epsilon DNA polymerase complex; [K02324] DNA polymerase epsilon subunit 1 [EC:2.7.7.7]; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10670] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A | 16.73 | 0.8598 |
| 13 |
Mapoly0001s0105
| [K02541] minichromosome maintenance protein 3; [KOG0479] DNA replication licensing factor, MCM3 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11630:SF46] DNA REPLICATION LICENSING FACTOR MCM3; [PF00493] MCM2/3/5 family; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain | 16.94 | 0.8720 |
| 14 |
Mapoly0039s0001
| - | 17.15 | 0.8110 |
| 15 |
Mapoly0095s0052
| [PF08839] DNA replication factor CDT1 like | 18.71 | 0.8362 |
| 16 |
Mapoly0038s0027
| [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PTHR10629:SF11] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF12047] Cytosine specific DNA methyltransferase replication foci domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. | 18.73 | 0.8185 |
| 17 |
Mapoly0023s0118
| [PTHR12446] TESMIN/TSO1-RELATED; [PF03638] Tesmin/TSO1-like CXC domain, cysteine-rich domain | 18.97 | 0.8652 |
| 18 |
Mapoly0038s0098
| [K03351] anaphase-promoting complex subunit 4; [PF12896] Anaphase-promoting complex, cyclosome, subunit 4; [KOG4640] Anaphase-promoting complex (APC), subunit 4; [GO:0030071] regulation of mitotic metaphase/anaphase transition; [PF12894] Anaphase-promoting complex subunit 4 WD40 domain; [PTHR13260] ANAPHASE PROMOTING COMPLEX SUBUNIT 4 (APC4) (CYCLOSOME SUBUNIT 4); [GO:0005680] anaphase-promoting complex; [GO:0031145] anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 20.74 | 0.7657 |
| 19 |
Mapoly0112s0002
| [PF14750] Integrator complex subunit 2; [K13139] integrator complex subunit 2; [GO:0032039] integrator complex | 21.91 | 0.7709 |
| 20 |
Mapoly0009s0056
| [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PF08311] Mad3/BUB1 homology region 1; [K02178] checkpoint serine/threonine-protein kinase [EC:2.7.11.1]; [KOG1166] Mitotic checkpoint serine/threonine protein kinase; [PTHR14030] MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 | 22.45 | 0.8521 |
| 21 |
Mapoly0013s0011
| [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) | 23.64 | 0.8170 |
| 22 |
Mapoly0034s0119
| [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity | 25.48 | 0.8676 |
| 23 |
Mapoly0154s0005
| [PTHR22852] LETHAL(2)DENTICLELESS PROTEIN (RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN); [KOG0265] U5 snRNP-specific protein-like factor and related proteins; [K11790] denticleless; [GO:0005515] protein binding; [PF00400] WD domain, G-beta repeat | 25.92 | 0.8585 |
| 24 |
Mapoly0084s0025
| [GO:0008565] protein transporter activity; [PTHR10527:SF1] IMPORTIN SUBUNIT BETA-1 (KARYOPHERIN SUBUNIT BETA-1); [GO:0006913] nucleocytoplasmic transport; [PTHR10527] IMPORTIN BETA | 26.72 | 0.7438 |
| 25 |
Mapoly0120s0004
| [PF00488] MutS domain V; [GO:0005524] ATP binding; [K08735] DNA mismatch repair protein MSH2; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PTHR11361:SF35] MUTS HOMOLOG 2, MSH2; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III; [KOG0219] Mismatch repair ATPase MSH2 (MutS family); [PF05190] MutS family domain IV | 26.83 | 0.8258 |
| 26 |
Mapoly0051s0085
| [KOG2267] Eukaryotic-type DNA primase, large subunit; [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10537] DNA PRIMASE LARGE SUBUNIT; [K02685] DNA primase large subunit [EC:2.7.7.-]; [PF04104] Eukaryotic and archaeal DNA primase, large subunit; [2.7.7.-] Nucleotidyltransferases. | 27.28 | 0.8283 |
| 27 |
Mapoly0098s0043
| [PF12717] non-SMC mitotic condensation complex subunit 1; [GO:0007076] mitotic chromosome condensation; [K11491] condensin-2 complex subunit D3; [PTHR14222:SF1] CONDENSIN; [PTHR14222] CONDENSIN | 27.57 | 0.8419 |
| 28 |
Mapoly0103s0079
| [GO:0003677] DNA binding; [PTHR13763:SF0] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0005634] nucleus; [GO:0006281] DNA repair; [GO:0004842] ubiquitin-protein ligase activity; [KOG4362] Transcriptional regulator BRCA1; [PTHR13763] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; [PF13771] PHD-like zinc-binding domain | 27.69 | 0.8632 |
| 29 |
Mapoly0045s0096
| [K08775] breast cancer 2 susceptibility protein; [PTHR11289] BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2; [GO:0003697] single-stranded DNA binding; [PF09169] BRCA2, helical; [PTHR11289:SF0] SUBFAMILY NOT NAMED; [GO:0006281] DNA repair; [PF09103] BRCA2, oligonucleotide/oligosaccharide-binding, domain 1; [GO:0000724] double-strand break repair via homologous recombination; [GO:0006310] DNA recombination | 29.10 | 0.7426 |
| 30 |
Mapoly0007s0066
| [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PTHR19306:SF1] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5 SMC5; [KOG0979] Structural maintenance of chromosome protein SMC5/Spr18, SMC superfamily; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0000724] double-strand break repair via homologous recombination | 29.39 | 0.8150 |
| 31 |
Mapoly0035s0108
| [GO:0005524] ATP binding; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23074] AAA ATPASE; [KOG0740] AAA+-type ATPase; [PF09336] Vps4 C terminal oligomerisation domain; [PTHR23074:SF17] FIDGETIN LIKE-1 | 29.75 | 0.7973 |
| 32 |
Mapoly0028s0066
| [GO:0005524] ATP binding; [KOG1112] Ribonucleotide reductase, alpha subunit; [GO:0006260] DNA replication; [GO:0055114] oxidation-reduction process; [GO:0004748] ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; [PF00317] Ribonucleotide reductase, all-alpha domain; [PTHR11573] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN; [PTHR11573:SF6] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN; [PF02867] Ribonucleotide reductase, barrel domain; [1.17.4.1] Ribonucleoside-diphosphate reductase.; [K10807] ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]; [PF03477] ATP cone domain | 29.85 | 0.8267 |
| 33 |
Mapoly0003s0057
| [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination | 30.40 | 0.8381 |
| 34 |
Mapoly0035s0099
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02321] DNA polymerase alpha subunit B; [PTHR23061:SF12] SUBFAMILY NOT NAMED; [KOG1625] DNA polymerase alpha-primase complex, polymerase-associated subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [PTHR23061] DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; [GO:0003887] DNA-directed DNA polymerase activity; [PF08418] DNA polymerase alpha subunit B N-terminal | 30.51 | 0.8497 |
| 35 |
Mapoly0023s0072
| [3.1.27.-] Endoribonucleases producing other than 5'-phosphomonoesters.; [K13148] integrator complex subunit 11 [EC:3.1.27.-]; [PF07521] RNA-metabolising metallo-beta-lactamase; [PTHR11203] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF00753] Metallo-beta-lactamase superfamily; [PTHR11203:SF11] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF10996] Beta-Casp domain; [KOG1136] Predicted cleavage and polyadenylation specificity factor (CPSF subunit) | 30.59 | 0.7791 |
| 36 |
Mapoly0029s0121
| [K11550] kinetochore protein Spc25, animal type; [PF08234] Chromosome segregation protein Spc25; [PTHR14281] FAMILY NOT NAMED | 31.08 | 0.8382 |
| 37 |
Mapoly0189s0011
| [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain | 31.75 | 0.8293 |
| 38 |
Mapoly0003s0120
| [GO:0003677] DNA binding; [PTHR12708:SF0] SUBFAMILY NOT NAMED; [GO:0006260] DNA replication; [PF12213] DNA polymerases epsilon N terminal; [2.7.7.7] DNA-directed DNA polymerase.; [PTHR12708] DNA POLYMERASE EPSILON SUBUNIT B; [KOG3818] DNA polymerase epsilon, subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [GO:0003887] DNA-directed DNA polymerase activity; [K02325] DNA polymerase epsilon subunit 2 [EC:2.7.7.7] | 31.81 | 0.8162 |
| 39 |
Mapoly0015s0164
| [GO:0003677] DNA binding; [PF02362] B3 DNA binding domain; [PTHR31391] FAMILY NOT NAMED | 32.31 | 0.7992 |
| 40 |
Mapoly0059s0004
| - | 32.94 | 0.7264 |
| 41 |
Mapoly0004s0096
| [K11548] kinetochore protein Nuf2; [GO:0007067] mitosis; [PTHR21650] MEMBRALIN/KINETOCHORE PROTEIN NUF2; [PF03800] Nuf2 family; [KOG4438] Centromere-associated protein NUF2; [GO:0000775] chromosome, centromeric region; [PTHR21650:SF2] KINETOCHORE PROTEIN NUF2 | 32.98 | 0.8540 |
| 42 |
Mapoly0001s0472
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED | 34.50 | 0.8265 |
| 43 |
Mapoly0064s0110
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR13394] ORIGIN RECOGNITION COMPLEX SUBUNIT 6; [PF05460] Origin recognition complex subunit 6 (ORC6); [GO:0005664] nuclear origin of replication recognition complex; [K02608] origin recognition complex subunit 6; [PTHR13394:SF0] SUBFAMILY NOT NAMED; [KOG4557] Origin recognition complex, subunit 6 | 35.24 | 0.8330 |
| 44 |
Mapoly0092s0013
| [GO:0003723] RNA binding; [PTHR13326] TRNA PSEUDOURIDINE SYNTHASE D; [GO:0001522] pseudouridine synthesis; [GO:0009451] RNA modification; [PF01142] tRNA pseudouridine synthase D (TruD); [GO:0009982] pseudouridine synthase activity; [KOG2339] Uncharacterized conserved protein | 36.33 | 0.7646 |
| 45 |
Mapoly0101s0048
| [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat | 36.47 | 0.8265 |
| 46 |
Mapoly0007s0014
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02540] minichromosome maintenance protein 2; [PF12619] Mini-chromosome maintenance protein 2; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PTHR11630:SF44] DNA REPLICATION LICENSING FACTOR MCM2; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [KOG0477] DNA replication licensing factor, MCM2 component | 37.82 | 0.8357 |
| 47 |
Mapoly0002s0169
| [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [K06632] wee1-like protein kinase [EC:2.7.11.1]; [PTHR11042] EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE (EIF2-ALPHA KINASE)-RELATED; [KOG0601] Cyclin-dependent kinase WEE1 | 39.12 | 0.8162 |
| 48 |
Mapoly0029s0012
| [GO:0005524] ATP binding; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [KOG0329] ATP-dependent RNA helicase; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding | 39.38 | 0.8162 |
| 49 |
Mapoly0030s0009
| [PF00505] HMG (high mobility group) box; [KOG0526] Nucleosome-binding factor SPN, POB3 subunit; [PF03531] Structure-specific recognition protein (SSRP1); [PTHR13711:SF39] SUBFAMILY NOT NAMED; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [PF08512] Histone chaperone Rttp106-like; [K09272] structure-specific recognition protein 1 | 39.50 | 0.7969 |
| 50 |
Mapoly0177s0008
| [GO:0006260] DNA replication; [PF13191] AAA ATPase domain; [GO:0005634] nucleus; [KOG2543] Origin recognition complex, subunit 5; [PF14630] Origin recognition complex (ORC) subunit 5 C-terminus; [PTHR12705] ORIGIN RECOGNITION COMPLEX SUBUNIT 5; [GO:0000808] origin recognition complex; [K02607] origin recognition complex subunit 5 | 40.00 | 0.8274 |
