Guide Gene
- Gene ID
- Mapoly0120s0004
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [PF00488] MutS domain V; [GO:0005524] ATP binding; [K08735] DNA mismatch repair protein MSH2; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PTHR11361:SF35] MUTS HOMOLOG 2, MSH2; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III; [KOG0219] Mismatch repair ATPase MSH2 (MutS family); [PF05190] MutS family domain IV
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0120s0004 [PF00488] MutS domain V; [GO:0005524] ATP binding; [K08735] DNA mismatch repair protein MSH2; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PTHR11361:SF35] MUTS HOMOLOG 2, MSH2; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III; [KOG0219] Mismatch repair ATPase MSH2 (MutS family); [PF05190] MutS family domain IV 0.00 1.0000 1 Mapoly0189s0010 [PTHR15272:SF0] SUBFAMILY NOT NAMED; [PF12253] Chromatin assembly factor 1 subunit A; [PTHR15272] CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A (CAF-1 SUBUNIT A) 1.00 0.8830 2 Mapoly0113s0037 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [KOG2577] Transcription factor E2F/dimerization partner (TDP); [PTHR12081] TRANSCRIPTION FACTOR E2F 1.41 0.8614 3 Mapoly0028s0066 [GO:0005524] ATP binding; [KOG1112] Ribonucleotide reductase, alpha subunit; [GO:0006260] DNA replication; [GO:0055114] oxidation-reduction process; [GO:0004748] ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; [PF00317] Ribonucleotide reductase, all-alpha domain; [PTHR11573] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN; [PTHR11573:SF6] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN; [PF02867] Ribonucleotide reductase, barrel domain; [1.17.4.1] Ribonucleoside-diphosphate reductase.; [K10807] ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]; [PF03477] ATP cone domain 7.35 0.8493 4 Mapoly0035s0108 [GO:0005524] ATP binding; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23074] AAA ATPASE; [KOG0740] AAA+-type ATPase; [PF09336] Vps4 C terminal oligomerisation domain; [PTHR23074:SF17] FIDGETIN LIKE-1 8.00 0.8351 5 Mapoly0045s0096 [K08775] breast cancer 2 susceptibility protein; [PTHR11289] BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2; [GO:0003697] single-stranded DNA binding; [PF09169] BRCA2, helical; [PTHR11289:SF0] SUBFAMILY NOT NAMED; [GO:0006281] DNA repair; [PF09103] BRCA2, oligonucleotide/oligosaccharide-binding, domain 1; [GO:0000724] double-strand break repair via homologous recombination; [GO:0006310] DNA recombination 8.06 0.7809 6 Mapoly0010s0152 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PTHR13561:SF5] DNA REPLICATION REGULATOR DPB11; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 9.49 0.8548 7 Mapoly0189s0011 [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain 12.12 0.8438 8 Mapoly0011s0137 [K03504] DNA polymerase delta subunit 3; [GO:0006260] DNA replication; [PTHR17598] FAMILY NOT NAMED; [PF09507] DNA polymerase subunit Cdc27; [GO:0005634] nucleus 13.42 0.8367 9 Mapoly0060s0056 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 14.14 0.8218 10 Mapoly0101s0048 [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat 14.70 0.8418 11 Mapoly0001s0105 [K02541] minichromosome maintenance protein 3; [KOG0479] DNA replication licensing factor, MCM3 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11630:SF46] DNA REPLICATION LICENSING FACTOR MCM3; [PF00493] MCM2/3/5 family; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 15.36 0.8544 12 Mapoly0007s0227 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02212] minichromosome maintenance protein 4 (cell division control protein 54); [KOG0478] DNA replication licensing factor, MCM4 component; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 15.49 0.8522 13 Mapoly0006s0290 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR10670:SF0] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A; [GO:0000166] nucleotide binding; [GO:0008270] zinc ion binding; [2.7.7.7] DNA-directed DNA polymerase.; [KOG1798] DNA polymerase epsilon, catalytic subunit A; [PF08490] Domain of unknown function (DUF1744); [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF00136] DNA polymerase family B; [GO:0008622] epsilon DNA polymerase complex; [K02324] DNA polymerase epsilon subunit 1 [EC:2.7.7.7]; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10670] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A 16.49 0.8433 14 Mapoly0108s0031 [GO:0005524] ATP binding; [K04499] RuvB-like protein 1 (pontin 52); [KOG1942] DNA helicase, TBP-interacting protein; [PF06068] TIP49 C-terminus; [GO:0043141] ATP-dependent 5'-3' DNA helicase activity; [GO:0003678] DNA helicase activity; [PTHR11093] RUVB-RELATED REPTIN AND PONTIN 17.29 0.8224 15 Mapoly0043s0112 [PTHR21780] UNCHARACTERIZED; [KOG4670] Uncharacterized conserved membrane protein; [PTHR21780:SF0] SUBFAMILY NOT NAMED; [PF09786] Cytochrome B561, N terminal 18.38 0.8377 16 Mapoly0039s0120 [KOG1805] DNA replication helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PTHR10887:SF14] DNA2-LIKE HELICASE; [3.6.4.12] DNA helicase.; [PF13086] AAA domain; [GO:0033567] DNA replication, Okazaki fragment processing; [PF01930] Domain of unknown function DUF83; [GO:0017108] 5'-flap endonuclease activity; [GO:0043142] single-stranded DNA-dependent ATPase activity; [PF13087] AAA domain; [PF08696] DNA replication factor Dna2; [K10742] DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12] 20.20 0.7916 17 Mapoly0064s0110 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR13394] ORIGIN RECOGNITION COMPLEX SUBUNIT 6; [PF05460] Origin recognition complex subunit 6 (ORC6); [GO:0005664] nuclear origin of replication recognition complex; [K02608] origin recognition complex subunit 6; [PTHR13394:SF0] SUBFAMILY NOT NAMED; [KOG4557] Origin recognition complex, subunit 6 20.71 0.8395 18 Mapoly0087s0021 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [KOG0969] DNA polymerase delta, catalytic subunit; [PTHR10322:SF11] DNA POLYMERASE DELTA CATALYTIC SUBUNIT; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [K02327] DNA polymerase delta subunit 1 [EC:2.7.7.7]; [PF14260] C4-type zinc-finger of DNA polymerase delta; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT 21.45 0.7970 19 Mapoly0005s0130 [GO:0042393] histone binding; [PF02182] SAD/SRA domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF13923] Zinc finger, C3HC4 type (RING finger); [PTHR14140] E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED 21.91 0.8036 20 Mapoly0185s0017 [GO:0030915] Smc5-Smc6 complex; [PF08746] RING-like domain; [KOG4718] Non-SMC (structural maintenance of chromosomes) element 1 protein (NSE1); [PTHR20973] NON-SMC ELEMENT 1-RELATED; [PF07574] Nse1 non-SMC component of SMC5-6 complex; [GO:0006281] DNA repair; [PTHR20973:SF0] SUBFAMILY NOT NAMED 22.45 0.8201 21 Mapoly0002s0042 [GO:0031011] Ino80 complex; [PTHR13052:SF0] SUBFAMILY NOT NAMED; [PTHR13052] NFRKB-RELATED 23.64 0.8007 22 Mapoly0029s0012 [GO:0005524] ATP binding; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [KOG0329] ATP-dependent RNA helicase; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding 23.92 0.8227 23 Mapoly0039s0001 - 23.92 0.7911 24 Mapoly0073s0079 [GO:0046907] intracellular transport; [GO:0005643] nuclear pore; [PTHR23138] RAN BINDING PROTEIN; [PTHR23138:SF46] ABR034WP; [PF00638] RanBP1 domain; [PF08911] NUP50 (Nucleoporin 50 kDa) 24.19 0.8053 25 Mapoly0039s0099 [PF00169] PH domain; [PTHR12092] PLECKSTRIN 26.00 0.7182 26 Mapoly0051s0073 [PF14675] FANCI solenoid 1; [PTHR21818:SF0] SUBFAMILY NOT NAMED; [PF14680] FANCI helical domain 2; [KOG4553] Uncharacterized conserved protein; [K10895] fanconi anemia group I protein; [PF14679] FANCI helical domain 1; [GO:0006281] DNA repair; [PF14678] FANCI solenoid 4; [PTHR21818] BC025462 PROTEIN; [PF14676] FANCI solenoid 2 26.83 0.8258 27 Mapoly0119s0016 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [KOG0480] DNA replication licensing factor, MCM6 component; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630:SF43] DNA REPLICATION LICENSING FACTOR MCM6; [K02542] minichromosome maintenance protein 6; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain 27.06 0.8394 28 Mapoly0080s0001 [GO:0005515] protein binding; [PTHR15271] CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; [KOG1009] Chromatin assembly complex 1 subunit B/CAC2 (contains WD40 repeats); [K10751] chromatin assembly factor 1 subunit B; [PF00400] WD domain, G-beta repeat 28.27 0.8331 29 Mapoly0075s0022 [KOG0482] DNA replication licensing factor, MCM7 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [K02210] minichromosome maintenance protein 7 (cell division control protein 47); [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [PTHR11630:SF26] DNA REPLICATION LICENSING FACTOR MCM7 28.50 0.8375 30 Mapoly0034s0119 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 28.81 0.8414 31 Mapoly0146s0045 [GO:0003723] RNA binding; [PTHR11207:SF1] RIBONUCLEASE III; [PF00035] Double-stranded RNA binding motif; [GO:0004525] ribonuclease III activity; [GO:0016075] rRNA catabolic process; [PTHR11207] RIBONUCLEASE III 28.84 0.8135 32 Mapoly0089s0012 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 29.66 0.7894 33 Mapoly0023s0118 [PTHR12446] TESMIN/TSO1-RELATED; [PF03638] Tesmin/TSO1-like CXC domain, cysteine-rich domain 30.30 0.8325 34 Mapoly0015s0164 [GO:0003677] DNA binding; [PF02362] B3 DNA binding domain; [PTHR31391] FAMILY NOT NAMED 33.17 0.7937 35 Mapoly0191s0002 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [K07374] tubulin alpha; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [KOG1376] Alpha tubulin; [GO:0005525] GTP binding 34.29 0.7942 36 Mapoly0006s0287 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02209] minichromosome maintenance protein 5 (cell division control protein 46); [PTHR11630:SF42] DNA REPLICATION LICENSING FACTOR MCM5; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain; [KOG0481] DNA replication licensing factor, MCM5 component 36.21 0.8260 37 Mapoly0133s0013 [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10615] HISTONE ACETYLTRANSFERASE; [PF00856] SET domain 37.15 0.8151 38 Mapoly0053s0080 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PF12230] Pre-mRNA splicing factor PRP21 like protein; [GO:0005515] protein binding; [PTHR15316:SF1] SPLICEOSOME ASSOCIATED PROTEIN 114; [PF00240] Ubiquitin family; [K12825] splicing factor 3A subunit 1; [PTHR15316] SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED; [PF01805] Surp module; [KOG0007] Splicing factor 3a, subunit 1 38.08 0.7857 39 Mapoly0013s0201 [PTHR23269:SF0] SUBFAMILY NOT NAMED; [KOG0128] RNA-binding protein SART3 (RRM superfamily); [PF05391] Lsm interaction motif; [GO:0003676] nucleic acid binding; [PTHR23269] RIBONUCLEOPROTEIN-RELATED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 39.87 0.7902 40 Mapoly0052s0054 [KOG0362] Chaperonin complex component, TCP-1 theta subunit (CCT8); [GO:0005524] ATP binding; [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family 41.35 0.7576 41 Mapoly0122s0062 [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 42.06 0.8180 42 Mapoly0016s0108 [GO:0005524] ATP binding; [K10755] replication factor C subunit 2/4; [KOG0991] Replication factor C, subunit RFC2; [PTHR11669] REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08542] Replication factor C C-terminal domain 43.16 0.7765 43 Mapoly0030s0009 [PF00505] HMG (high mobility group) box; [KOG0526] Nucleosome-binding factor SPN, POB3 subunit; [PF03531] Structure-specific recognition protein (SSRP1); [PTHR13711:SF39] SUBFAMILY NOT NAMED; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [PF08512] Histone chaperone Rttp106-like; [K09272] structure-specific recognition protein 1 45.44 0.7848 44 Mapoly0140s0032 [PTHR12748] ORIGIN RECOGNITION COMPLEX SUBUNIT 3; [PTHR12748:SF0] SUBFAMILY NOT NAMED; [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02605] origin recognition complex subunit 3; [PF07034] Origin recognition complex (ORC) subunit 3 N-terminus; [KOG2538] Origin recognition complex, subunit 3; [GO:0005664] nuclear origin of replication recognition complex; [PF02178] AT hook motif 46.48 0.8223 45 Mapoly0035s0099 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02321] DNA polymerase alpha subunit B; [PTHR23061:SF12] SUBFAMILY NOT NAMED; [KOG1625] DNA polymerase alpha-primase complex, polymerase-associated subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [PTHR23061] DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; [GO:0003887] DNA-directed DNA polymerase activity; [PF08418] DNA polymerase alpha subunit B N-terminal 46.77 0.8208 46 Mapoly0103s0079 [GO:0003677] DNA binding; [PTHR13763:SF0] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0005634] nucleus; [GO:0006281] DNA repair; [GO:0004842] ubiquitin-protein ligase activity; [KOG4362] Transcriptional regulator BRCA1; [PTHR13763] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; [PF13771] PHD-like zinc-binding domain 48.06 0.8233 47 Mapoly0098s0032 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [PF11721] Di-glucose binding within endoplasmic reticulum; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 48.10 0.8208 48 Mapoly0023s0062 [K11086] small nuclear ribonucleoprotein B and B'; [PTHR10701] SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N; [KOG3168] U1 snRNP component; [PF01423] LSM domain 48.66 0.7694 49 Mapoly0043s0064 [PF10979] Protein of unknown function (DUF2786) 48.93 0.8060 50 Mapoly0033s0129 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0003910] DNA ligase (ATP) activity; [PF04679] ATP dependent DNA ligase C terminal region; [PTHR10459] DNA LIGASE; [K10747] DNA ligase 1 [EC:6.5.1.1]; [PF01068] ATP dependent DNA ligase domain; [6.5.1.1] DNA ligase (ATP).; [GO:0006281] DNA repair; [PF04675] DNA ligase N terminus; [PTHR10459:SF10] DNA LIGASE I; [GO:0006310] DNA recombination; [KOG0967] ATP-dependent DNA ligase I 49.72 0.7542 51 Mapoly0030s0102 [PF08317] Spc7 kinetochore protein 50.50 0.8118 52 Mapoly0055s0064 - 52.25 0.8117 53 Mapoly0096s0020 [GO:0005524] ATP binding; [PF02359] Cell division protein 48 (CDC48), N-terminal domain; [PF02933] Cell division protein 48 (CDC48), domain 2; [PF00004] ATPase family associated with various cellular activities (AAA); [K13525] transitional endoplasmic reticulum ATPase; [PTHR23077] AAA-FAMILY ATPASE; [KOG0730] AAA+-type ATPase 54.99 0.7720 54 Mapoly0016s0080 [K14399] polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]; [PF03205] Molybdopterin guanine dinucleotide synthesis protein B; [KOG2749] mRNA cleavage and polyadenylation factor IA/II complex, subunit CLP1; [2.7.1.78] Polynucleotide 5'-hydroxyl-kinase.; [PTHR12755] CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P; [PF06807] Pre-mRNA cleavage complex II protein Clp1 55.51 0.7663 55 Mapoly0003s0057 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination 56.08 0.8099 56 Mapoly0001s0208 [PTHR31431] FAMILY NOT NAMED; [KOG4833] Uncharacterized conserved protein; [K14311] nuclear pore complex protein Nup188; [PF10487] Nucleoporin subcomplex protein binding to Pom34 56.28 0.7799 57 Mapoly0209s0008 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF67] DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 56.51 0.8138 58 Mapoly0014s0033 [KOG4285] Mitotic phosphoprotein; [PTHR21527] FAMILY NOT NAMED; [K14313] nuclear pore complex protein Nup53; [PF05172] Nup53/35/40-type RNA recognition motif 57.16 0.7430 59 Mapoly0061s0085 [PF14868] Domain of unknown function (DUF4487) 57.39 0.7894 60 Mapoly0027s0105 - 58.99 0.7449 61 Mapoly0007s0066 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PTHR19306:SF1] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5 SMC5; [KOG0979] Structural maintenance of chromosome protein SMC5/Spr18, SMC superfamily; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0000724] double-strand break repair via homologous recombination 59.40 0.7830 62 Mapoly0011s0202 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain 59.97 0.8118 63 Mapoly0051s0075 [GO:0003723] RNA binding; [KOG2190] PolyC-binding proteins alphaCP-1 and related KH domain proteins; [PTHR10288] KH DOMAIN CONTAINING RNA BINDING PROTEIN; [PTHR10288:SF102] ANKYRIN REPEAT-CONTAINING PROTEIN; [PF00013] KH domain 61.03 0.7290 64 Mapoly0154s0005 [PTHR22852] LETHAL(2)DENTICLELESS PROTEIN (RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN); [KOG0265] U5 snRNP-specific protein-like factor and related proteins; [K11790] denticleless; [GO:0005515] protein binding; [PF00400] WD domain, G-beta repeat 61.19 0.8105 65 Mapoly0098s0043 [PF12717] non-SMC mitotic condensation complex subunit 1; [GO:0007076] mitotic chromosome condensation; [K11491] condensin-2 complex subunit D3; [PTHR14222:SF1] CONDENSIN; [PTHR14222] CONDENSIN 61.87 0.8003 66 Mapoly0166s0018 [K10739] replication factor A2; [KOG3108] Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit; [PF08784] Replication protein A C terminal; [PTHR13989] REPLICATION PROTEIN A-RELATED; [GO:0003676] nucleic acid binding; [PF01336] OB-fold nucleic acid binding domain 62.57 0.7988 67 Mapoly0071s0007 [GO:0005524] ATP binding; [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family; [K09494] T-complex protein 1 subunit beta; [KOG0363] Chaperonin complex component, TCP-1 beta subunit (CCT2) 63.06 0.7730 68 Mapoly0029s0121 [K11550] kinetochore protein Spc25, animal type; [PF08234] Chromosome segregation protein Spc25; [PTHR14281] FAMILY NOT NAMED 63.21 0.7967 69 Mapoly0038s0027 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PTHR10629:SF11] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF12047] Cytosine specific DNA methyltransferase replication foci domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 65.73 0.7625 70 Mapoly0052s0086 [PF05641] Agenet domain; [PTHR31917] FAMILY NOT NAMED 65.82 0.7858 71 Mapoly0046s0055 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [KOG1374] Gamma tubulin; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [GO:0031122] cytoplasmic microtubule organization; [PTHR11588:SF7] TUBULIN GAMMA CHAIN; [K10389] tubulin gamma; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0007020] microtubule nucleation; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0000930] gamma-tubulin complex; [GO:0043234] protein complex; [GO:0005525] GTP binding 67.04 0.7523 72 Mapoly0042s0049 - 67.19 0.7840 73 Mapoly0112s0002 [PF14750] Integrator complex subunit 2; [K13139] integrator complex subunit 2; [GO:0032039] integrator complex 67.48 0.7352 74 Mapoly0005s0267 [PTHR23111] ZINC FINGER PROTEIN; [GO:0008270] zinc ion binding; [PF00641] Zn-finger in Ran binding protein and others 67.50 0.7769 75 Mapoly0113s0048 [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [KOG1408] WD40 repeat protein; [PF00400] WD domain, G-beta repeat 67.76 0.8033 76 Mapoly0033s0057 [2.3.1.-] Transferring groups other than amino-acyl groups.; [PTHR11076:SF1] ESTABLISHMENT OF COHESION 1 (ECO1) HOMOLOG; [PF13880] ESCO1/2 acetyl-transferase; [PF13878] zinc-finger of acetyl-transferase ESCO; [KOG3014] Protein involved in establishing cohesion between sister chromatids during DNA replication; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [K11268] N-acetyltransferase [EC:2.3.1.-] 67.97 0.8028 77 Mapoly0069s0084 [3.6.5.5] Dynamin GTPase.; [KOG0446] Vacuolar sorting protein VPS1, dynamin, and related proteins; [K01528] dynamin GTPase [EC:3.6.5.5]; [PF02212] Dynamin GTPase effector domain; [PF00350] Dynamin family; [PTHR11566] DYNAMIN; [GO:0003924] GTPase activity; [PTHR11566:SF21] SUBFAMILY NOT NAMED; [GO:0005525] GTP binding; [PF01031] Dynamin central region 68.41 0.7447 78 Mapoly0037s0093 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG4280] Kinesin-like protein; [PTHR24115:SF87] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [PF12711] Kinesin motor; [GO:0003777] microtubule motor activity 69.86 0.7641 79 Mapoly0079s0005 [GO:0008080] N-acetyltransferase activity; [GO:0016568] chromatin modification; [PF00583] Acetyltransferase (GNAT) family; [GO:0005634] nucleus; [GO:0004402] histone acetyltransferase activity; [GO:0016573] histone acetylation; [KOG2696] Histone acetyltransferase type b catalytic subunit; [GO:0006348] chromatin silencing at telomere; [2.3.1.48] Histone acetyltransferase.; [PTHR12046] HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT; [K11303] histone acetyltransferase 1 [EC:2.3.1.48]; [PF10394] Histone acetyl transferase HAT1 N-terminus 69.99 0.7831 80 Mapoly0051s0023 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III 70.99 0.7947 81 Mapoly0159s0020 [K05544] tRNA-dihydrouridine synthase 3 [EC:1.-.-.-]; [GO:0050660] flavin adenine dinucleotide binding; [GO:0055114] oxidation-reduction process; [PTHR11082:SF8] TRNA-DIHYDROURIDINE SYNTHASE 3; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PF01207] Dihydrouridine synthase (Dus); [KOG2333] Uncharacterized conserved protein; [GO:0008033] tRNA processing; [PTHR11082] TRNA-DIHYDROURIDINE SYNTHASE; [GO:0046872] metal ion binding; [GO:0017150] tRNA dihydrouridine synthase activity; [1.-.-.-] Oxidoreductases. 71.73 0.7537 82 Mapoly0031s0066 [PTHR12087:SF0] SUBFAMILY NOT NAMED; [KOG2228] Origin recognition complex, subunit 4; [PF13191] AAA ATPase domain; [PF14629] Origin recognition complex (ORC) subunit 4 C-terminus; [PTHR12087] ORIGIN RECOGNITION COMPLEX SUBUNIT 4; [K02606] origin recognition complex subunit 4 74.68 0.6105 83 Mapoly0029s0003 [KOG1824] TATA-binding protein-interacting protein; [PTHR12696] TIP120; [PF08623] TATA-binding protein interacting (TIP20); [PF13646] HEAT repeats 75.47 0.7625 84 Mapoly0051s0086 [PF05859] Mis12 protein; [GO:0007067] mitosis; [GO:0005634] nucleus; [GO:0000775] chromosome, centromeric region; [GO:0007049] cell cycle 77.50 0.7676 85 Mapoly0019s0059 [PTHR31398:SF0] SUBFAMILY NOT NAMED; [PTHR31398] FAMILY NOT NAMED; [PF03962] Mnd1 family; [KOG3433] Protein involved in meiotic recombination/predicted coiled-coil protein 78.93 0.7757 86 Mapoly0102s0001 [K06228] fused [EC:2.7.11.1]; [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR22983:SF6] MAPK KINASE 2-RELATED; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [KOG0598] Ribosomal protein S6 kinase and related proteins; [PF13646] HEAT repeats 79.37 0.7843 87 Mapoly0120s0055 [GO:0003677] DNA binding; [PTHR12486] APRATAXIN-RELATED; [PF13671] AAA domain; [PF01661] Macro domain; [GO:0006281] DNA repair; [KOG0562] Predicted hydrolase (HIT family); [PF11969] Scavenger mRNA decapping enzyme C-term binding; [GO:0033699] DNA 5'-adenosine monophosphate hydrolase activity; [PF10283] Zinc-finger (CX5CX6HX5H) motif; [3.-.-.-] Hydrolases.; [K10863] aprataxin [EC:3.-.-.-]; [PTHR12486:SF4] APRATAXIN (FORKHEAD-ASSOCIATED DOMAIN HISTIDINE-TRIAD LIKE PROTEIN) 79.97 0.5917 88 Mapoly0013s0011 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 81.95 0.7633 89 Mapoly0112s0022 [PTHR19932] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; [GO:0005515] protein binding; [KOG1274] WD40 repeat protein; [K11274] chromosome transmission fidelity protein 4; [PTHR19932:SF10] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN 1; [PF00400] WD domain, G-beta repeat; [PF12341] Protein of unknown function (DUF3639) 81.98 0.7893 90 Mapoly0048s0048 [PTHR31802] FAMILY NOT NAMED 82.27 0.7604 91 Mapoly0147s0033 [PF07738] Sad1 / UNC-like C-terminal; [PTHR12911] SAD1/UNC-84-LIKE PROTEIN-RELATED; [KOG2687] Spindle pole body protein, contains UNC-84 domain 83.14 0.7569 92 Mapoly0072s0051 [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [KOG0597] Serine-threonine protein kinase FUSED; [GO:0006468] protein phosphorylation 83.52 0.7829 93 Mapoly0132s0046 [PF00855] PWWP domain; [PTHR12550] HEPATOMA-DERIVED GROWTH FACTOR-RELATED; [PTHR12550:SF5] UNCHARACTERIZED 84.59 0.7366 94 Mapoly0004s0250 [GO:0005643] nuclear pore; [PF07817] GLE1-like protein; [GO:0016973] poly(A)+ mRNA export from nucleus; [KOG2412] Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor; [PTHR12960:SF0] SUBFAMILY NOT NAMED; [PTHR12960] GLE-1-RELATED 85.93 0.7541 95 Mapoly0197s0017 [PTHR10751] GUANYLATE BINDING PROTEIN; [KOG1003] Actin filament-coating protein tropomyosin; [PTHR10751:SF2] GUANYLATE BINDING PROTEIN; [PF02263] Guanylate-binding protein, N-terminal domain; [GO:0003924] GTPase activity; [GO:0005525] GTP binding; [PF02841] Guanylate-binding protein, C-terminal domain 86.08 0.7081 96 Mapoly0067s0068 [KOG2266] Chromatin-associated protein Dek and related proteins, contains SAP DNA binding domain; [PTHR13468:SF1] DEK ONCOGENE; [PF08766] DEK C terminal domain; [PTHR13468] DEK PROTEIN 89.19 0.7638 97 Mapoly0004s0169 [GO:0003677] DNA binding; [GO:0006338] chromatin remodeling; [GO:0005524] ATP binding; [PF09110] HAND; [K11654] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]; [GO:0043044] ATP-dependent chromatin remodeling; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [GO:0005634] nucleus; [PTHR10799:SF73] ISWI CHROMATIN-REMODELING COMPLEX ATPASE ISW1; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [KOG0385] Chromatin remodeling complex WSTF-ISWI, small subunit; [GO:0003676] nucleic acid binding; [GO:0031491] nucleosome binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [PF09111] SLIDE 89.63 0.7673 98 Mapoly0011s0143 [PTHR15481:SF0] SUBFAMILY NOT NAMED; [K14325] RNA-binding protein with serine-rich domain 1; [PTHR15481] RIBONUCLEIC ACID BINDING PROTEIN S1; [GO:0003676] nucleic acid binding; [KOG0130] RNA-binding protein RBM8/Tsunagi (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 90.50 0.7622 99 Mapoly0010s0124 [K14320] aladin; [KOG2139] WD40 repeat protein; [GO:0005515] protein binding; [PTHR14494] ALADIN/ADRACALIN/AAAS; [PTHR14494:SF0] SUBFAMILY NOT NAMED; [PF00400] WD domain, G-beta repeat 90.81 0.7377 100 Mapoly0060s0012 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [K11498] centromeric protein E; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 92.97 0.7783 101 Mapoly0002s0004 [KOG1189] Global transcriptional regulator, cell division control protein; [PF00557] Metallopeptidase family M24; [PF08512] Histone chaperone Rttp106-like; [PTHR13980] CDC68 RELATED; [PF08644] FACT complex subunit (SPT16/CDC68) 93.01 0.7163 102 Mapoly0105s0060 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [K12898] heterogeneous nuclear ribonucleoprotein F/H; [KOG4211] Splicing factor hnRNP-F and related RNA-binding proteins; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED 93.20 0.7702 103 Mapoly0051s0092 [GO:0007264] small GTPase mediated signal transduction; [K07975] Rho family, other; [PTHR24072] RHO FAMILY GTPASE; [KOG0393] Ras-related small GTPase, Rho type; [PF00071] Ras family; [GO:0005525] GTP binding 96.99 0.7074 104 Mapoly0001s0378 [PTHR32086] FAMILY NOT NAMED; [K10891] fanconi anemia group D2 protein; [GO:0006281] DNA repair; [KOG4712] Uncharacterized conserved protein; [PF14631] Fanconi anaemia protein FancD2 nuclease 99.29 0.7536 105 Mapoly0013s0109 [PF00514] Armadillo/beta-catenin-like repeat; [PF00651] BTB/POZ domain; [GO:0005515] protein binding; [KOG0166] Karyopherin (importin) alpha; [PTHR23315] BETA CATENIN-RELATED ARMADILLO REPEAT-CONTAINING 100.76 0.7345 106 Mapoly0051s0085 [KOG2267] Eukaryotic-type DNA primase, large subunit; [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10537] DNA PRIMASE LARGE SUBUNIT; [K02685] DNA primase large subunit [EC:2.7.7.-]; [PF04104] Eukaryotic and archaeal DNA primase, large subunit; [2.7.7.-] Nucleotidyltransferases. 102.40 0.7567 107 Mapoly0055s0120 - 102.91 0.7440 108 Mapoly0177s0008 [GO:0006260] DNA replication; [PF13191] AAA ATPase domain; [GO:0005634] nucleus; [KOG2543] Origin recognition complex, subunit 5; [PF14630] Origin recognition complex (ORC) subunit 5 C-terminus; [PTHR12705] ORIGIN RECOGNITION COMPLEX SUBUNIT 5; [GO:0000808] origin recognition complex; [K02607] origin recognition complex subunit 5 105.51 0.7621 109 Mapoly0080s0039 [PTHR15081] NUCLEAR AUTOANTIGENIC SPERM PROTEIN (NASP)-RELATED; [PF13414] TPR repeat; [PF10516] SHNi-TPR 106.21 0.7436 110 Mapoly0045s0042 [KOG2475] CDC45 (cell division cycle 45)-like protein; [GO:0006270] DNA replication initiation; [PF02724] CDC45-like protein; [PTHR10507:SF0] CDC45-RELATED PROTEIN; [PTHR10507] CDC45-RELATED PROTEIN; [K06628] cell division control protein 45 107.48 0.7682 111 Mapoly0004s0300 [GO:0005524] ATP binding; [PTHR11909:SF7] CELL DIVISION CONTROL PROTEIN 7; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K02214] cell division control protein 7 [EC:2.7.11.1]; [KOG1167] Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination; [GO:0006468] protein phosphorylation; [PTHR11909] CASEIN KINASE-RELATED 107.82 0.7684 112 Mapoly0011s0047 [PTHR12972] DOWNSTREAM NEIGHBOR OF SON 108.81 0.7307 113 Mapoly0009s0121 [GO:0005524] ATP binding; [GO:0044267] cellular protein metabolic process; [KOG0364] Chaperonin complex component, TCP-1 gamma subunit (CCT3); [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family; [GO:0006457] protein folding; [GO:0051082] unfolded protein binding 108.89 0.7207 114 Mapoly0095s0052 [PF08839] DNA replication factor CDT1 like 108.98 0.7494 115 Mapoly0029s0136 [PTHR21206:SF0] SUBFAMILY NOT NAMED; [PF05916] GINS complex protein; [KOG3176] Predicted alpha-helical protein, potentially involved in replication/repair; [PTHR21206] SLD5 PROTEIN; [K10735] GINS complex subunit 4 109.17 0.7445 116 Mapoly0061s0120 [PTHR13269] UNCHARACTERIZED; [PTHR13269:SF6] SUBFAMILY NOT NAMED; [PF09531] Nucleoporin protein Ndc1-Nup 109.50 0.7497 117 Mapoly0081s0071 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [PF00628] PHD-finger; [GO:0005515] protein binding; [PF12738] twin BRCT domain; [GO:0046872] metal ion binding 109.80 0.7627 118 Mapoly0091s0017 [GO:0005515] protein binding; [PTHR22937] RING FINGER CONTAINING PROTEIN; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [KOG2177] Predicted E3 ubiquitin ligase; [K11985] TRAF-interacting protein 110.68 0.7156 119 Mapoly0167s0015 [KOG1076] Translation initiation factor 3, subunit c (eIF-3c); [K03252] translation initiation factor eIF-3 subunit 8; [PF05470] Eukaryotic translation initiation factor 3 subunit 8 N-terminus; [PTHR13937:SF0] SUBFAMILY NOT NAMED; [GO:0003743] translation initiation factor activity; [GO:0005515] protein binding; [PTHR13937] EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 (EIF3S8)-RELATED; [GO:0031369] translation initiation factor binding; [PF01399] PCI domain; [GO:0006413] translational initiation; [GO:0005852] eukaryotic translation initiation factor 3 complex 111.00 0.7030 120 Mapoly0004s0096 [K11548] kinetochore protein Nuf2; [GO:0007067] mitosis; [PTHR21650] MEMBRALIN/KINETOCHORE PROTEIN NUF2; [PF03800] Nuf2 family; [KOG4438] Centromere-associated protein NUF2; [GO:0000775] chromosome, centromeric region; [PTHR21650:SF2] KINETOCHORE PROTEIN NUF2 111.21 0.7636 121 Mapoly0097s0064 [PTHR13710:SF1] ROTHMUND-THOMSON SYNDROME DNA HELICASE RECQ4; [GO:0005524] ATP binding; [PF11719] DNA replication and checkpoint protein; [K10730] ATP-dependent DNA helicase Q4 [EC:3.6.4.12]; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [GO:0003676] nucleic acid binding; [PF02037] SAP domain 111.22 0.7616 122 Mapoly0013s0062 [GO:0003677] DNA binding; [PTHR15348:SF0] SUBFAMILY NOT NAMED; [PF01388] ARID/BRIGHT DNA binding domain; [GO:0005622] intracellular; [PTHR15348] AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN (ARID DOMAIN- CONTAINING PROTEIN) (DEAD RINGER PROTEIN) (B-CELL REGULATOR OF IGH TRANSCRIPTION) (BRIGHT) 111.55 0.7429 123 Mapoly0053s0106 - 114.11 0.7634 124 Mapoly0009s0056 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PF08311] Mad3/BUB1 homology region 1; [K02178] checkpoint serine/threonine-protein kinase [EC:2.7.11.1]; [KOG1166] Mitotic checkpoint serine/threonine protein kinase; [PTHR14030] MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 115.03 0.7545 125 Mapoly0010s0062 [KOG2250] Glutamate/leucine/phenylalanine/valine dehydrogenases; [GO:0055114] oxidation-reduction process; [PTHR11606] GLUTAMATE DEHYDROGENASE; [GO:0016491] oxidoreductase activity; [PF00208] Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; [K00262] glutamate dehydrogenase (NADP+) [EC:1.4.1.4]; [GO:0006520] cellular amino acid metabolic process; [PTHR11606:SF4] SUBFAMILY NOT NAMED; [1.4.1.4] Glutamate dehydrogenase (NADP(+)).; [PF02812] Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 115.11 0.7402 126 Mapoly0042s0007 [GO:0003677] DNA binding; [K02213] cell division control protein 6; [KOG2227] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase; [PF13401] AAA domain; [PF01429] Methyl-CpG binding domain; [GO:0005634] nucleus; [PF09079] CDC6, C terminal; [PTHR10763] CELL DIVISION CONTROL PROTEIN 6-RELATED 116.16 0.7391 127 Mapoly0030s0020 [KOG2545] Conserved membrane protein; [PTHR13489:SF0] SUBFAMILY NOT NAMED; [PF13615] Putative alanine racemase; [PF09739] Mini-chromosome maintenance replisome factor; [PTHR13489] UNCHARACTERIZED 116.65 0.7638 128 Mapoly0053s0016 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 116.91 0.7543 129 Mapoly0007s0014 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02540] minichromosome maintenance protein 2; [PF12619] Mini-chromosome maintenance protein 2; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PTHR11630:SF44] DNA REPLICATION LICENSING FACTOR MCM2; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [KOG0477] DNA replication licensing factor, MCM2 component 117.24 0.7628 130 Mapoly0013s0048 [KOG0381] HMG box-containing protein; [PF00505] HMG (high mobility group) box; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN 117.30 0.7633 131 Mapoly0001s0472 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED 117.36 0.7569 132 Mapoly0021s0043 - 117.78 0.7328 133 Mapoly0013s0016 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR31614] FAMILY NOT NAMED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08661] Replication factor A protein 3; [GO:0006310] DNA recombination 117.85 0.7422 134 Mapoly0005s0061 [PF00089] Trypsin; [PTHR22939] SERINE PROTEASE FAMILY S1C HTRA-RELATED; [GO:0005515] protein binding; [PF13180] PDZ domain; [KOG1320] Serine protease; [GO:0004252] serine-type endopeptidase activity; [GO:0006508] proteolysis 118.66 0.7231 135 Mapoly0001s0044 [PTHR31110] FAMILY NOT NAMED 119.80 0.7472 136 Mapoly0116s0028 [PTHR23074:SF19] KATANIN-RELATED; [GO:0005524] ATP binding; [3.6.4.3] Microtubule-severing ATPase.; [K07767] microtubule-severing ATPase [EC:3.6.4.3]; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0738] AAA+-type ATPase; [PTHR23074] AAA ATPASE; [PF09336] Vps4 C terminal oligomerisation domain 122.41 0.7120 137 Mapoly0061s0010 [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10536] DNA PRIMASE SMALL SUBUNIT; [KOG2851] Eukaryotic-type DNA primase, catalytic (small) subunit; [K02684] DNA primase small subunit [EC:2.7.7.-]; [2.7.7.-] Nucleotidyltransferases.; [PF01896] Eukaryotic and archaeal DNA primase small subunit 122.47 0.7558 138 Mapoly0002s0035 - 123.26 0.7344 139 Mapoly0001s0474 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [K11294] nucleolin; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 123.49 0.6578 140 Mapoly0001s0457 [PTHR14360:SF1] UNCHARACTERIZED; [PF07798] Protein of unknown function (DUF1640); [KOG3156] Uncharacterized membrane protein; [PTHR14360] UNCHARACTERIZED 123.60 0.6933 141 Mapoly0070s0034 [KOG0108] mRNA cleavage and polyadenylation factor I complex, subunit RNA15; [PF14327] Hinge domain of cleavage stimulation factor subunit 2; [PTHR23139:SF8] RNA RECOGNITION MOTIF CONTAINING PROTEIN; [PTHR23139] RNA-BINDING PROTEIN; [GO:0003676] nucleic acid binding; [K14407] cleavage stimulation factor subunit 2; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 123.87 0.7215 142 Mapoly0068s0001 [K10736] minichromosome maintenance protein 10; [GO:0006260] DNA replication; [PTHR13454] FAMILY NOT NAMED; [PF09329] Primase zinc finger; [GO:0005634] nucleus 124.14 0.7455 143 Mapoly0062s0008 [PF02295] Adenosine deaminase z-alpha domain; [GO:0003723] RNA binding; [GO:0003726] double-stranded RNA adenosine deaminase activity 124.94 0.6898 144 Mapoly0078s0017 - 125.07 0.7560 145 Mapoly0107s0034 [3.5.1.98] Histone deacetylase.; [KOG1342] Histone deacetylase complex, catalytic component RPD3; [K06067] histone deacetylase 1/2 [EC:3.5.1.98]; [PF00850] Histone deacetylase domain; [PTHR10625] HISTONE DEACETYLASE 125.48 0.7216 146 Mapoly0001s0263 [PF08766] DEK C terminal domain; [GO:0005515] protein binding; [KOG1946] RNA polymerase I transcription factor UAF; [PF02201] SWIB/MDM2 domain; [PTHR13844] BRG-1 ASSOCIATED FACTOR 60 (BAF60) 125.88 0.6161 147 Mapoly0029s0022 [PTHR23002] ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN; [PF06273] Plant specific eukaryotic initiation factor 4B; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding 126.03 0.6999 148 Mapoly0111s0057 [PF13865] C-terminal duplication domain of Friend of PRMT1 126.64 0.7025 149 Mapoly0003s0120 [GO:0003677] DNA binding; [PTHR12708:SF0] SUBFAMILY NOT NAMED; [GO:0006260] DNA replication; [PF12213] DNA polymerases epsilon N terminal; [2.7.7.7] DNA-directed DNA polymerase.; [PTHR12708] DNA POLYMERASE EPSILON SUBUNIT B; [KOG3818] DNA polymerase epsilon, subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [GO:0003887] DNA-directed DNA polymerase activity; [K02325] DNA polymerase epsilon subunit 2 [EC:2.7.7.7] 127.56 0.7325 150 Mapoly0007s0143 [KOG2235] Uncharacterized conserved protein; [PTHR31057] FAMILY NOT NAMED; [PF09743] Uncharacterized conserved protein (DUF2042); [PTHR31057:SF0] SUBFAMILY NOT NAMED 127.84 0.6935 151 Mapoly0001s0011 [K02219] cyclin-dependent kinase regulatory subunit CKS1; [KOG3484] Cyclin-dependent protein kinase CDC28, regulatory subunit CKS1, and related proteins; [PF01111] Cyclin-dependent kinase regulatory subunit; [GO:0016538] cyclin-dependent protein serine/threonine kinase regulator activity; [GO:0007049] cell cycle; [PTHR23415] CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 127.98 0.7239 152 Mapoly0113s0005 - 127.98 0.7351 153 Mapoly0033s0098 [PTHR16047] RFWD3 PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PTHR16047:SF7] RFWD3 PROTEIN-RELATED; [KOG1645] RING-finger-containing E3 ubiquitin ligase 129.15 0.7352 154 Mapoly0067s0081 [GO:0003723] RNA binding; [K13126] polyadenylate-binding protein; [PF00658] Poly-adenylate binding protein, unique domain; [KOG0123] Polyadenylate-binding protein (RRM superfamily); [PTHR24011] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 129.16 0.6815 155 Mapoly0083s0034 - 129.17 0.7176 156 Mapoly0114s0009 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [PF00514] Armadillo/beta-catenin-like repeat; [GO:0005515] protein binding; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [KOG0240] Kinesin (SMY1 subfamily); [GO:0008017] microtubule binding; [PTHR24115:SF221] SUBFAMILY NOT NAMED; [GO:0003777] microtubule motor activity 129.58 0.7072 157 Mapoly0007s0080 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 129.61 0.7479 158 Mapoly0043s0128 [KOG0381] HMG box-containing protein; [GO:0003677] DNA binding; [PF00505] HMG (high mobility group) box; [PF01388] ARID/BRIGHT DNA binding domain; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [GO:0005622] intracellular 129.98 0.7148 159 Mapoly0043s0082 [PF07899] Frigida-like protein; [PTHR31791] FAMILY NOT NAMED 131.13 0.7130 160 Mapoly0004s0286 [PTHR12663:SF0] SUBFAMILY NOT NAMED; [K11267] sister chromatid cohesion protein PDS5; [PTHR12663] ANDROGEN INDUCED INHIBITOR OF PROLIFERATION (AS3) / PDS5-RELATED; [KOG1525] Sister chromatid cohesion complex Cohesin, subunit PDS5 131.20 0.7464 161 Mapoly0030s0146 - 131.42 0.6569 162 Mapoly0008s0250 [PTHR24007] BRCA1-ASSOCIATED PROTEIN; [PF00917] MATH domain; [GO:0005515] protein binding; [GO:0006281] DNA repair; [PF14631] Fanconi anaemia protein FancD2 nuclease; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 131.45 0.7225 163 Mapoly0002s0324 [GO:0005524] ATP binding; [GO:0016021] integral to membrane; [PTHR24223] FAMILY NOT NAMED; [PF00664] ABC transporter transmembrane region; [GO:0016887] ATPase activity; [GO:0006810] transport; [GO:0055085] transmembrane transport; [KOG0054] Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily; [GO:0042626] ATPase activity, coupled to transmembrane movement of substances; [PF00005] ABC transporter 131.48 0.6599 164 Mapoly0004s0058 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PTHR13215:SF4] SUBFAMILY NOT NAMED; [PF08766] DEK C terminal domain; [PF02229] Transcriptional Coactivator p15 (PC4); [KOG2712] Transcriptional coactivator; [PTHR13215] RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; [GO:0003713] transcription coactivator activity 132.34 0.6975 165 Mapoly0047s0069 [GO:0005524] ATP binding; [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family; [KOG0358] Chaperonin complex component, TCP-1 delta subunit (CCT4) 133.03 0.7237 166 Mapoly0037s0034 [K10744] ribonuclease H2 subunit B; [PTHR13383] FAMILY NOT NAMED; [PF09468] Ydr279p protein family (RNase H2 complex component); [GO:0005634] nucleus 133.29 0.7499 167 Mapoly0036s0142 [GO:0003677] DNA binding; [KOG1757] Histone 2A; [K11251] histone H2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 134.23 0.7400 168 Mapoly0004s0213 [PF03215] Rad17 cell cycle checkpoint protein; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PTHR12172] CELL CYCLE CHECKPOINT PROTEIN RAD17; [KOG1970] Checkpoint RAD17-RFC complex, RAD17/RAD24 component; [PTHR12172:SF0] SUBFAMILY NOT NAMED; [K06662] cell cycle checkpoint protein; [GO:0007049] cell cycle 135.04 0.7071 169 Mapoly0001s0446 - 135.22 0.7236 170 Mapoly0026s0077 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [2.7.11.1] Non-specific serine/threonine protein kinase.; [PF08064] UME (NUC010) domain; [PF00454] Phosphatidylinositol 3- and 4-kinase; [K06640] ataxia telangiectasia and Rad3 related [EC:2.7.11.1]; [GO:0004674] protein serine/threonine kinase activity; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [KOG0890] Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination 137.56 0.7208 171 Mapoly0221s0003 - 138.43 0.7376 172 Mapoly0091s0013 [GO:0003723] RNA binding; [KOG2202] U2 snRNP splicing factor, small subunit, and related proteins; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PTHR12620] U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT; [GO:0005634] nucleus; [K12836] splicing factor U2AF 35 kDa subunit; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [GO:0046872] metal ion binding 138.82 0.7385 173 Mapoly0087s0074 [GO:0005685] U1 snRNP; [PF06220] U1 zinc finger; [GO:0008270] zinc ion binding; [GO:0000398] mRNA splicing, via spliceosome; [KOG3454] U1 snRNP-specific protein C; [GO:0000387] spliceosomal snRNP assembly; [PTHR31148] FAMILY NOT NAMED 139.91 0.7323 174 Mapoly0155s0001 [GO:0016597] amino acid binding; [PF01842] ACT domain; [GO:0008152] metabolic process; [PTHR31096] FAMILY NOT NAMED 140.79 0.7109 175 Mapoly0118s0005 [GO:0008233] peptidase activity; [3.4.22.49] Separase.; [K02365] separase [EC:3.4.22.49]; [GO:0005634] nucleus; [PF03568] Peptidase family C50; [GO:0006508] proteolysis; [PTHR12792] EXTRA SPINDLE POLES 1-RELATED 141.03 0.7391 176 Mapoly0005s0208 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [KOG0244] Kinesin-like protein; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [K10395] kinesin family member 4/7/21/27; [GO:0003777] microtubule motor activity 141.11 0.7274 177 Mapoly0034s0111 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 142.89 0.7423 178 Mapoly0042s0086 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K08737] DNA mismatch repair protein MSH6; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PTHR11361:SF31] MUTS HOMOLOG 6, MSH6; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 144.11 0.7230 179 Mapoly0063s0041 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR23340] ARGININE/SERINE RICH SPLICING FACTOR SF4/14; [PF01585] G-patch domain; [GO:0003676] nucleic acid binding; [PF01805] Surp module 145.75 0.7108 180 Mapoly0005s0174 [GO:0005524] ATP binding; [KOG0933] Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E); [GO:0007076] mitotic chromosome condensation; [GO:0005515] protein binding; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0000796] condensin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PTHR18937:SF9] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC2; [K06674] structural maintenance of chromosome 2; [PF06470] SMC proteins Flexible Hinge Domain 145.86 0.7503 181 Mapoly0108s0028 [GO:0003723] RNA binding; [GO:0003743] translation initiation factor activity; [GO:0031369] translation initiation factor binding; [GO:0003676] nucleic acid binding; [GO:0006413] translational initiation; [K03253] translation initiation factor eIF-3 subunit 9; [PTHR14068:SF0] SUBFAMILY NOT NAMED; [KOG2314] Translation initiation factor 3, subunit b (eIF-3b); [PTHR14068] EUKARYOTIC TRANSLATION INITIATION FACTOR 3 (EIF3)-RELATED; [PF08662] Eukaryotic translation initiation factor eIF2A; [GO:0005852] eukaryotic translation initiation factor 3 complex; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 146.79 0.6729 182 Mapoly0043s0044 [PTHR13257:SF0] SUBFAMILY NOT NAMED; [K14318] nuclear pore complex protein Nup88; [PF10168] Nuclear pore component; [KOG4460] Nuclear pore complex, Nup88/rNup84 component; [PTHR13257] NUCLEOPORIN NUP84-RELATED 147.36 0.7140 183 Mapoly0005s0067 [PTHR15242:SF0] SUBFAMILY NOT NAMED; [PTHR15242] SPLICING FACTOR, ARGININE/SERINE-RICH 2,RNAP C-TERM INTERACTING PROTEIN; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 148.98 0.7358 184 Mapoly0067s0049 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF00580] UvrD/REP helicase N-terminal domain; [PF13361] UvrD-like helicase C-terminal domain; [GO:0016787] hydrolase activity; [GO:0004003] ATP-dependent DNA helicase activity; [PTHR11070] UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER 149.71 0.6852 185 Mapoly0109s0044 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PF04057] Replication factor-A protein 1, N-terminal domain; [GO:0005634] nucleus; [KOG0851] Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins; [PF08646] Replication factor-A C terminal domain; [GO:0003676] nucleic acid binding; [K07466] replication factor A1; [PTHR23273] REPLICATION FACTOR A 1, RFA1; [PF01336] OB-fold nucleic acid binding domain 150.40 0.7063 186 Mapoly0109s0019 [KOG1375] Beta tubulin; [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [K07375] tubulin beta; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [GO:0005525] GTP binding 150.41 0.6940 187 Mapoly0042s0023 [GO:0005524] ATP binding; [2.7.12.1] Dual-specificity kinase.; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [K08866] serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]; [PTHR22974] MIXED LINEAGE PROTEIN KINASE 150.52 0.7397 188 Mapoly0028s0115 [PTHR12640:SF0] SUBFAMILY NOT NAMED; [GO:0008250] oligosaccharyltransferase complex; [GO:0016021] integral to membrane; [PTHR12640] RIBOPHORIN II; [KOG2447] Oligosaccharyltransferase, delta subunit (ribophorin II); [PF05817] Oligosaccharyltransferase subunit Ribophorin II; [GO:0006487] protein N-linked glycosylation 151.12 0.6400 189 Mapoly0179s0001 [PTHR10994] RETICULON; [PF02453] Reticulon; [KOG1792] Reticulon 151.20 0.7399 190 Mapoly0023s0072 [3.1.27.-] Endoribonucleases producing other than 5'-phosphomonoesters.; [K13148] integrator complex subunit 11 [EC:3.1.27.-]; [PF07521] RNA-metabolising metallo-beta-lactamase; [PTHR11203] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF00753] Metallo-beta-lactamase superfamily; [PTHR11203:SF11] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF10996] Beta-Casp domain; [KOG1136] Predicted cleavage and polyadenylation specificity factor (CPSF subunit) 151.31 0.6972 191 Mapoly0109s0054 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PF02229] Transcriptional Coactivator p15 (PC4); [KOG2712] Transcriptional coactivator; [PTHR13215] RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; [GO:0003713] transcription coactivator activity 152.00 0.7288 192 Mapoly0010s0094 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [PF00454] Phosphatidylinositol 3- and 4-kinase; [KOG0889] Histone acetyltransferase SAGA, TRRAP/TRA1 component, PI-3 kinase superfamily; [PTHR11139:SF1] ATM-RELATED; [K08874] transformation/transcription domain-associated protein; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED 152.20 0.7226 193 Mapoly0098s0009 [K01104] protein-tyrosine phosphatase [EC:3.1.3.48]; [PF00581] Rhodanese-like domain; [PTHR10828:SF17] M-PHASE INDUCER PHOSPHATASE (DUAL SPECIFICITY PHOSPHATASE CDC25); [PTHR10828] M-PHASE INDUCER PHOSPHATASE (DUAL SPECIFICITY PHOSPHATASE CDC25); [3.1.3.48] Protein-tyrosine-phosphatase. 152.40 0.7321 194 Mapoly0075s0032 [GO:0003677] DNA binding; [GO:0006275] regulation of DNA replication; [GO:0030337] DNA polymerase processivity factor activity; [PTHR11352] PROLIFERATING CELL NUCLEAR ANTIGEN; [PF00705] Proliferating cell nuclear antigen, N-terminal domain; [K04802] proliferating cell nuclear antigen; [KOG1636] DNA polymerase delta processivity factor (proliferating cell nuclear antigen); [PF02747] Proliferating cell nuclear antigen, C-terminal domain 155.45 0.7140 195 Mapoly0070s0095 [PTHR23215] ZINC FINGER PROTEIN 207; [KOG2893] Zn finger protein 155.75 0.7079 196 Mapoly0005s0256 [PF12220] U1 small nuclear ribonucleoprotein of 70kDa MW N terminal; [KOG0113] U1 small nuclear ribonucleoprotein (RRM superfamily); [PTHR13952:SF5] PREDICTED: HYPOTHETICAL PROTEIN, PARTIAL; [PTHR13952] U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD; [K11093] U1 small nuclear ribonucleoprotein 70kDa; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 158.51 0.7033 197 Mapoly0078s0012 [GO:0006396] RNA processing; [PTHR11061] RNA M5U METHYLTRANSFERASE FAMILY; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0008173] RNA methyltransferase activity; [PF05958] tRNA (Uracil-5-)-methyltransferase; [GO:0046872] metal ion binding; [KOG2187] tRNA uracil-5-methyltransferase and related tRNA-modifying enzymes 159.37 0.7045 198 Mapoly0002s0237 [PTHR12864] RAN BINDING PROTEIN 9-RELATED; [PF10607] CTLH/CRA C-terminal to LisH motif domain; [GO:0005515] protein binding; [KOG1477] SPRY domain-containing proteins; [PTHR12864:SF1] RAN BINDING PROTEIN 9-RELATED; [PF00622] SPRY domain 159.42 0.6373 199 Mapoly0005s0051 [GO:0003723] RNA binding; [GO:0000339] RNA cap binding; [GO:0045292] mRNA cis splicing, via spliceosome; [GO:0051028] mRNA transport; [PF02854] MIF4G domain; [GO:0005515] protein binding; [KOG1104] Nuclear cap-binding complex, subunit NCBP1/CBP80; [K12882] nuclear cap-binding protein subunit 1; [GO:0016070] RNA metabolic process; [PTHR12412] CAP BINDING PROTEIN; [GO:0005846] nuclear cap binding complex; [PF09090] MIF4G like; [PF09088] MIF4G like 159.47 0.7364 200 Mapoly0086s0078 [GO:0003677] DNA binding; [GO:0006275] regulation of DNA replication; [GO:0030337] DNA polymerase processivity factor activity; [PTHR11352] PROLIFERATING CELL NUCLEAR ANTIGEN; [PF00705] Proliferating cell nuclear antigen, N-terminal domain; [KOG1636] DNA polymerase delta processivity factor (proliferating cell nuclear antigen); [PF02747] Proliferating cell nuclear antigen, C-terminal domain 160.21 0.7117