| 1 |
Mapoly0185s0017
| [GO:0030915] Smc5-Smc6 complex; [PF08746] RING-like domain; [KOG4718] Non-SMC (structural maintenance of chromosomes) element 1 protein (NSE1); [PTHR20973] NON-SMC ELEMENT 1-RELATED; [PF07574] Nse1 non-SMC component of SMC5-6 complex; [GO:0006281] DNA repair; [PTHR20973:SF0] SUBFAMILY NOT NAMED | 1.41 | 0.8526 |
| 2 |
Mapoly0011s0137
| [K03504] DNA polymerase delta subunit 3; [GO:0006260] DNA replication; [PTHR17598] FAMILY NOT NAMED; [PF09507] DNA polymerase subunit Cdc27; [GO:0005634] nucleus | 1.73 | 0.8628 |
| 3 |
Mapoly0015s0164
| [GO:0003677] DNA binding; [PF02362] B3 DNA binding domain; [PTHR31391] FAMILY NOT NAMED | 5.92 | 0.8226 |
| 4 |
Mapoly0120s0004
| [PF00488] MutS domain V; [GO:0005524] ATP binding; [K08735] DNA mismatch repair protein MSH2; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PTHR11361:SF35] MUTS HOMOLOG 2, MSH2; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III; [KOG0219] Mismatch repair ATPase MSH2 (MutS family); [PF05190] MutS family domain IV | 8.00 | 0.8351 |
| 5 |
Mapoly0004s0213
| [PF03215] Rad17 cell cycle checkpoint protein; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PTHR12172] CELL CYCLE CHECKPOINT PROTEIN RAD17; [KOG1970] Checkpoint RAD17-RFC complex, RAD17/RAD24 component; [PTHR12172:SF0] SUBFAMILY NOT NAMED; [K06662] cell cycle checkpoint protein; [GO:0007049] cell cycle | 8.37 | 0.8035 |
| 6 |
Mapoly0046s0055
| [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [KOG1374] Gamma tubulin; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [GO:0031122] cytoplasmic microtubule organization; [PTHR11588:SF7] TUBULIN GAMMA CHAIN; [K10389] tubulin gamma; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0007020] microtubule nucleation; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0000930] gamma-tubulin complex; [GO:0043234] protein complex; [GO:0005525] GTP binding | 11.00 | 0.8034 |
| 7 |
Mapoly0039s0001
| - | 12.65 | 0.7956 |
| 8 |
Mapoly0006s0287
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02209] minichromosome maintenance protein 5 (cell division control protein 46); [PTHR11630:SF42] DNA REPLICATION LICENSING FACTOR MCM5; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain; [KOG0481] DNA replication licensing factor, MCM5 component | 13.30 | 0.8364 |
| 9 |
Mapoly0043s0062
| [GO:0003677] DNA binding; [GO:0006284] base-excision repair; [PTHR10359] A/G-SPECIFIC ADENINE GLYCOSYLASE/ENDONUCLEASE III; [PF14815] NUDIX domain; [K03575] A/G-specific adenine glycosylase [EC:3.2.2.-]; [KOG1921] Endonuclease III; [PF00730] HhH-GPD superfamily base excision DNA repair protein; [PF00633] Helix-hairpin-helix motif; [3.2.2.-] Hydrolyzing N-glycosyl compounds. | 16.73 | 0.7836 |
| 10 |
Mapoly0091s0017
| [GO:0005515] protein binding; [PTHR22937] RING FINGER CONTAINING PROTEIN; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [KOG2177] Predicted E3 ubiquitin ligase; [K11985] TRAF-interacting protein | 17.86 | 0.7833 |
| 11 |
Mapoly0133s0013
| [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10615] HISTONE ACETYLTRANSFERASE; [PF00856] SET domain | 21.17 | 0.8057 |
| 12 |
Mapoly0004s0250
| [GO:0005643] nuclear pore; [PF07817] GLE1-like protein; [GO:0016973] poly(A)+ mRNA export from nucleus; [KOG2412] Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor; [PTHR12960:SF0] SUBFAMILY NOT NAMED; [PTHR12960] GLE-1-RELATED | 21.35 | 0.7919 |
| 13 |
Mapoly0004s0008
| - | 21.82 | 0.7744 |
| 14 |
Mapoly0007s0227
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02212] minichromosome maintenance protein 4 (cell division control protein 54); [KOG0478] DNA replication licensing factor, MCM4 component; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain | 23.11 | 0.8181 |
| 15 |
Mapoly0007s0066
| [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PTHR19306:SF1] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5 SMC5; [KOG0979] Structural maintenance of chromosome protein SMC5/Spr18, SMC superfamily; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0000724] double-strand break repair via homologous recombination | 24.37 | 0.7942 |
| 16 |
Mapoly0002s0042
| [GO:0031011] Ino80 complex; [PTHR13052:SF0] SUBFAMILY NOT NAMED; [PTHR13052] NFRKB-RELATED | 25.81 | 0.7731 |
| 17 |
Mapoly0073s0079
| [GO:0046907] intracellular transport; [GO:0005643] nuclear pore; [PTHR23138] RAN BINDING PROTEIN; [PTHR23138:SF46] ABR034WP; [PF00638] RanBP1 domain; [PF08911] NUP50 (Nucleoporin 50 kDa) | 26.38 | 0.7846 |
| 18 |
Mapoly0112s0022
| [PTHR19932] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; [GO:0005515] protein binding; [KOG1274] WD40 repeat protein; [K11274] chromosome transmission fidelity protein 4; [PTHR19932:SF10] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN 1; [PF00400] WD domain, G-beta repeat; [PF12341] Protein of unknown function (DUF3639) | 26.46 | 0.8077 |
| 19 |
Mapoly0051s0023
| [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III | 27.17 | 0.8038 |
| 20 |
Mapoly0033s0129
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0003910] DNA ligase (ATP) activity; [PF04679] ATP dependent DNA ligase C terminal region; [PTHR10459] DNA LIGASE; [K10747] DNA ligase 1 [EC:6.5.1.1]; [PF01068] ATP dependent DNA ligase domain; [6.5.1.1] DNA ligase (ATP).; [GO:0006281] DNA repair; [PF04675] DNA ligase N terminus; [PTHR10459:SF10] DNA LIGASE I; [GO:0006310] DNA recombination; [KOG0967] ATP-dependent DNA ligase I | 29.70 | 0.7656 |
| 21 |
Mapoly0051s0073
| [PF14675] FANCI solenoid 1; [PTHR21818:SF0] SUBFAMILY NOT NAMED; [PF14680] FANCI helical domain 2; [KOG4553] Uncharacterized conserved protein; [K10895] fanconi anemia group I protein; [PF14679] FANCI helical domain 1; [GO:0006281] DNA repair; [PF14678] FANCI solenoid 4; [PTHR21818] BC025462 PROTEIN; [PF14676] FANCI solenoid 2 | 29.75 | 0.7973 |
| 22 |
Mapoly0113s0037
| [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [KOG2577] Transcription factor E2F/dimerization partner (TDP); [PTHR12081] TRANSCRIPTION FACTOR E2F | 29.93 | 0.7749 |
| 23 |
Mapoly0046s0087
| [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PTHR24420:SF145] SUBFAMILY NOT NAMED; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE | 30.28 | 0.7170 |
| 24 |
Mapoly0101s0048
| [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat | 30.38 | 0.7987 |
| 25 |
Mapoly0005s0130
| [GO:0042393] histone binding; [PF02182] SAD/SRA domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF13923] Zinc finger, C3HC4 type (RING finger); [PTHR14140] E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED | 30.50 | 0.7756 |
| 26 |
Mapoly0042s0007
| [GO:0003677] DNA binding; [K02213] cell division control protein 6; [KOG2227] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase; [PF13401] AAA domain; [PF01429] Methyl-CpG binding domain; [GO:0005634] nucleus; [PF09079] CDC6, C terminal; [PTHR10763] CELL DIVISION CONTROL PROTEIN 6-RELATED | 31.45 | 0.7867 |
| 27 |
Mapoly0052s0086
| [PF05641] Agenet domain; [PTHR31917] FAMILY NOT NAMED | 33.24 | 0.7942 |
| 28 |
Mapoly0010s0062
| [KOG2250] Glutamate/leucine/phenylalanine/valine dehydrogenases; [GO:0055114] oxidation-reduction process; [PTHR11606] GLUTAMATE DEHYDROGENASE; [GO:0016491] oxidoreductase activity; [PF00208] Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; [K00262] glutamate dehydrogenase (NADP+) [EC:1.4.1.4]; [GO:0006520] cellular amino acid metabolic process; [PTHR11606:SF4] SUBFAMILY NOT NAMED; [1.4.1.4] Glutamate dehydrogenase (NADP(+)).; [PF02812] Glu/Leu/Phe/Val dehydrogenase, dimerisation domain | 33.67 | 0.7872 |
| 29 |
Mapoly0075s0022
| [KOG0482] DNA replication licensing factor, MCM7 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [K02210] minichromosome maintenance protein 7 (cell division control protein 47); [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [PTHR11630:SF26] DNA REPLICATION LICENSING FACTOR MCM7 | 33.94 | 0.8003 |
| 30 |
Mapoly0122s0062
| [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 | 35.50 | 0.7980 |
| 31 |
Mapoly0019s0059
| [PTHR31398:SF0] SUBFAMILY NOT NAMED; [PTHR31398] FAMILY NOT NAMED; [PF03962] Mnd1 family; [KOG3433] Protein involved in meiotic recombination/predicted coiled-coil protein | 37.15 | 0.7875 |
| 32 |
Mapoly0159s0020
| [K05544] tRNA-dihydrouridine synthase 3 [EC:1.-.-.-]; [GO:0050660] flavin adenine dinucleotide binding; [GO:0055114] oxidation-reduction process; [PTHR11082:SF8] TRNA-DIHYDROURIDINE SYNTHASE 3; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PF01207] Dihydrouridine synthase (Dus); [KOG2333] Uncharacterized conserved protein; [GO:0008033] tRNA processing; [PTHR11082] TRNA-DIHYDROURIDINE SYNTHASE; [GO:0046872] metal ion binding; [GO:0017150] tRNA dihydrouridine synthase activity; [1.-.-.-] Oxidoreductases. | 40.56 | 0.7667 |
| 33 |
Mapoly0021s0043
| - | 47.75 | 0.7706 |
| 34 |
Mapoly0060s0056
| [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. | 47.75 | 0.7724 |
| 35 |
Mapoly0112s0002
| [PF14750] Integrator complex subunit 2; [K13139] integrator complex subunit 2; [GO:0032039] integrator complex | 48.74 | 0.7425 |
| 36 |
Mapoly0004s0058
| [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PTHR13215:SF4] SUBFAMILY NOT NAMED; [PF08766] DEK C terminal domain; [PF02229] Transcriptional Coactivator p15 (PC4); [KOG2712] Transcriptional coactivator; [PTHR13215] RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; [GO:0003713] transcription coactivator activity | 49.07 | 0.7432 |
| 37 |
Mapoly0051s0086
| [PF05859] Mis12 protein; [GO:0007067] mitosis; [GO:0005634] nucleus; [GO:0000775] chromosome, centromeric region; [GO:0007049] cell cycle | 49.84 | 0.7737 |
| 38 |
Mapoly0119s0016
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [KOG0480] DNA replication licensing factor, MCM6 component; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630:SF43] DNA REPLICATION LICENSING FACTOR MCM6; [K02542] minichromosome maintenance protein 6; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain | 51.81 | 0.7869 |
| 39 |
Mapoly0166s0018
| [K10739] replication factor A2; [KOG3108] Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit; [PF08784] Replication protein A C terminal; [PTHR13989] REPLICATION PROTEIN A-RELATED; [GO:0003676] nucleic acid binding; [PF01336] OB-fold nucleic acid binding domain | 52.44 | 0.7844 |
| 40 |
Mapoly0087s0021
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [KOG0969] DNA polymerase delta, catalytic subunit; [PTHR10322:SF11] DNA POLYMERASE DELTA CATALYTIC SUBUNIT; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [K02327] DNA polymerase delta subunit 1 [EC:2.7.7.7]; [PF14260] C4-type zinc-finger of DNA polymerase delta; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT | 52.48 | 0.7615 |
| 41 |
Mapoly0013s0048
| [KOG0381] HMG box-containing protein; [PF00505] HMG (high mobility group) box; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN | 52.74 | 0.7838 |
| 42 |
Mapoly0045s0096
| [K08775] breast cancer 2 susceptibility protein; [PTHR11289] BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2; [GO:0003697] single-stranded DNA binding; [PF09169] BRCA2, helical; [PTHR11289:SF0] SUBFAMILY NOT NAMED; [GO:0006281] DNA repair; [PF09103] BRCA2, oligonucleotide/oligosaccharide-binding, domain 1; [GO:0000724] double-strand break repair via homologous recombination; [GO:0006310] DNA recombination | 57.79 | 0.6997 |
| 43 |
Mapoly0005s0267
| [PTHR23111] ZINC FINGER PROTEIN; [GO:0008270] zinc ion binding; [PF00641] Zn-finger in Ran binding protein and others | 57.83 | 0.7699 |
| 44 |
Mapoly0189s0011
| [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain | 57.91 | 0.7723 |
| 45 |
Mapoly0014s0033
| [KOG4285] Mitotic phosphoprotein; [PTHR21527] FAMILY NOT NAMED; [K14313] nuclear pore complex protein Nup53; [PF05172] Nup53/35/40-type RNA recognition motif | 58.97 | 0.7386 |
| 46 |
Mapoly0009s0067
| [PTHR31789] FAMILY NOT NAMED | 59.75 | 0.7492 |
| 47 |
Mapoly0140s0032
| [PTHR12748] ORIGIN RECOGNITION COMPLEX SUBUNIT 3; [PTHR12748:SF0] SUBFAMILY NOT NAMED; [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02605] origin recognition complex subunit 3; [PF07034] Origin recognition complex (ORC) subunit 3 N-terminus; [KOG2538] Origin recognition complex, subunit 3; [GO:0005664] nuclear origin of replication recognition complex; [PF02178] AT hook motif | 59.90 | 0.7840 |
| 48 |
Mapoly0033s0098
| [PTHR16047] RFWD3 PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PTHR16047:SF7] RFWD3 PROTEIN-RELATED; [KOG1645] RING-finger-containing E3 ubiquitin ligase | 60.03 | 0.7616 |
| 49 |
Mapoly0001s0378
| [PTHR32086] FAMILY NOT NAMED; [K10891] fanconi anemia group D2 protein; [GO:0006281] DNA repair; [KOG4712] Uncharacterized conserved protein; [PF14631] Fanconi anaemia protein FancD2 nuclease | 60.83 | 0.7644 |
| 50 |
Mapoly0061s0010
| [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10536] DNA PRIMASE SMALL SUBUNIT; [KOG2851] Eukaryotic-type DNA primase, catalytic (small) subunit; [K02684] DNA primase small subunit [EC:2.7.7.-]; [2.7.7.-] Nucleotidyltransferases.; [PF01896] Eukaryotic and archaeal DNA primase small subunit | 62.67 | 0.7747 |
