Guide Gene
- Gene ID
- Mapoly0043s0062
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [GO:0003677] DNA binding; [GO:0006284] base-excision repair; [PTHR10359] A/G-SPECIFIC ADENINE GLYCOSYLASE/ENDONUCLEASE III; [PF14815] NUDIX domain; [K03575] A/G-specific adenine glycosylase [EC:3.2.2.-]; [KOG1921] Endonuclease III; [PF00730] HhH-GPD superfamily base excision DNA repair protein; [PF00633] Helix-hairpin-helix motif; [3.2.2.-] Hydrolyzing N-glycosyl compounds.
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0043s0062 [GO:0003677] DNA binding; [GO:0006284] base-excision repair; [PTHR10359] A/G-SPECIFIC ADENINE GLYCOSYLASE/ENDONUCLEASE III; [PF14815] NUDIX domain; [K03575] A/G-specific adenine glycosylase [EC:3.2.2.-]; [KOG1921] Endonuclease III; [PF00730] HhH-GPD superfamily base excision DNA repair protein; [PF00633] Helix-hairpin-helix motif; [3.2.2.-] Hydrolyzing N-glycosyl compounds. 0.00 1.0000 1 Mapoly0004s0213 [PF03215] Rad17 cell cycle checkpoint protein; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PTHR12172] CELL CYCLE CHECKPOINT PROTEIN RAD17; [KOG1970] Checkpoint RAD17-RFC complex, RAD17/RAD24 component; [PTHR12172:SF0] SUBFAMILY NOT NAMED; [K06662] cell cycle checkpoint protein; [GO:0007049] cell cycle 1.00 0.8548 2 Mapoly0091s0017 [GO:0005515] protein binding; [PTHR22937] RING FINGER CONTAINING PROTEIN; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [KOG2177] Predicted E3 ubiquitin ligase; [K11985] TRAF-interacting protein 3.16 0.8042 3 Mapoly0002s0230 [GO:0003677] DNA binding; [GO:0000784] nuclear chromosome, telomeric region; [PF02765] Telomeric single stranded DNA binding POT1/CDC13; [GO:0043047] single-stranded telomeric DNA binding; [PTHR14513] PROTECTION OF TELOMERES 1; [KOG4757] Predicted telomere binding protein; [GO:0000723] telomere maintenance 4.12 0.7684 4 Mapoly0006s0078 [GO:0005515] protein binding; [PTHR10253] POLYCOMB PROTEIN; [KOG1034] Transcriptional repressor EED/ESC/FIE, required for transcriptional silencing, WD repeat superfamily; [K11462] polycomb protein EED; [PF00400] WD domain, G-beta repeat 7.48 0.7965 5 Mapoly0001s0348 [KOG1342] Histone deacetylase complex, catalytic component RPD3; [PF00850] Histone deacetylase domain; [PTHR10625] HISTONE DEACETYLASE 8.37 0.7738 6 Mapoly0100s0038 [GO:0007264] small GTPase mediated signal transduction; [PTHR24073] FAMILY NOT NAMED; [KOG0098] GTPase Rab2, small G protein superfamily; [PF15305] Intraflagellar transport protein 43; [PF00071] Ras family; [GO:0005525] GTP binding; [GO:0030991] intraflagellar transport particle A 8.49 0.7847 7 Mapoly0001s0022 [GO:0016020] membrane; [GO:0055085] transmembrane transport; [PTHR30566] YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; [PF00924] Mechanosensitive ion channel 9.95 0.7813 8 Mapoly0011s0143 [PTHR15481:SF0] SUBFAMILY NOT NAMED; [K14325] RNA-binding protein with serine-rich domain 1; [PTHR15481] RIBONUCLEIC ACID BINDING PROTEIN S1; [GO:0003676] nucleic acid binding; [KOG0130] RNA-binding protein RBM8/Tsunagi (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 11.49 0.8004 9 Mapoly0011s0137 [K03504] DNA polymerase delta subunit 3; [GO:0006260] DNA replication; [PTHR17598] FAMILY NOT NAMED; [PF09507] DNA polymerase subunit Cdc27; [GO:0005634] nucleus 14.70 0.7929 10 Mapoly0035s0108 [GO:0005524] ATP binding; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23074] AAA ATPASE; [KOG0740] AAA+-type ATPase; [PF09336] Vps4 C terminal oligomerisation domain; [PTHR23074:SF17] FIDGETIN LIKE-1 16.73 0.7836 11 Mapoly0091s0013 [GO:0003723] RNA binding; [KOG2202] U2 snRNP splicing factor, small subunit, and related proteins; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PTHR12620] U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT; [GO:0005634] nucleus; [K12836] splicing factor U2AF 35 kDa subunit; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [GO:0046872] metal ion binding 17.46 0.7957 12 Mapoly0015s0164 [GO:0003677] DNA binding; [PF02362] B3 DNA binding domain; [PTHR31391] FAMILY NOT NAMED 19.29 0.7810 13 Mapoly0009s0136 [PTHR24012] FAMILY NOT NAMED; [KOG0126] Predicted RNA-binding protein (RRM superfamily); [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 22.63 0.7713 14 Mapoly0004s0058 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PTHR13215:SF4] SUBFAMILY NOT NAMED; [PF08766] DEK C terminal domain; [PF02229] Transcriptional Coactivator p15 (PC4); [KOG2712] Transcriptional coactivator; [PTHR13215] RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; [GO:0003713] transcription coactivator activity 22.65 0.7518 15 Mapoly0036s0154 [KOG2606] OTU (ovarian tumor)-like cysteine protease; [PTHR12419] OTU DOMAIN CONTAINING PROTEIN; [PTHR12419:SF10] gb def: ENSANGP00000019868 (Fragment); [PF02338] OTU-like cysteine protease 22.65 0.7836 16 Mapoly0036s0012 [GO:0003723] RNA binding; [KOG3013] Exosomal 3'-5' exoribonuclease complex, subunit Rrp4; [PTHR21321] PNAS-3 RELATED; [PTHR21321:SF1] PNAS-3 RELATED; [K03679] exosome complex component RRP4; [GO:0000178] exosome (RNase complex) 22.72 0.6780 17 Mapoly0005s0205 [PF00226] DnaJ domain; [KOG0719] Molecular chaperone (DnaJ superfamily); [PTHR24078] DNAJ HOMOLOG SUBFAMILY C MEMBER 24.25 0.7848 18 Mapoly0109s0054 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PF02229] Transcriptional Coactivator p15 (PC4); [KOG2712] Transcriptional coactivator; [PTHR13215] RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; [GO:0003713] transcription coactivator activity 28.16 0.7764 19 Mapoly0016s0080 [K14399] polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]; [PF03205] Molybdopterin guanine dinucleotide synthesis protein B; [KOG2749] mRNA cleavage and polyadenylation factor IA/II complex, subunit CLP1; [2.7.1.78] Polynucleotide 5'-hydroxyl-kinase.; [PTHR12755] CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P; [PF06807] Pre-mRNA cleavage complex II protein Clp1 29.33 0.7605 20 Mapoly0004s0008 - 31.02 0.7374 21 Mapoly0023s0050 [PF11559] Afadin- and alpha -actinin-Binding; [PTHR21736] VERNALIZATION-INSENSITIVE PROTEIN 3 33.41 0.7684 22 Mapoly0073s0077 [PF07719] Tetratricopeptide repeat; [KOG1174] Anaphase-promoting complex (APC), subunit 7; [GO:0005515] protein binding; [PF13181] Tetratricopeptide repeat; [PTHR12558:SF8] ANAPHASE PROMOTING COMPLEX SUBUNIT 7; [PTHR12558] CELL DIVISION CYCLE 16,23,27 38.11 0.6802 23 Mapoly0167s0006 - 40.79 0.7455 24 Mapoly0024s0100 [GO:0005524] ATP binding; [PTHR11669] REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; [KOG0990] Replication factor C, subunit RFC5; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08542] Replication factor C C-terminal domain; [K10756] replication factor C subunit 3/5 42.07 0.7724 25 Mapoly0039s0001 - 42.21 0.7441 26 Mapoly0109s0009 [K03574] 7,8-dihydro-8-oxoguanine triphosphatase [EC:3.6.1.-]; [GO:0016787] hydrolase activity; [PTHR22769] MUTT/NUDIX HYDROLASE; [3.6.1.-] In phosphorous-containing anhydrides.; [PF00293] NUDIX domain 42.40 0.7147 27 Mapoly0010s0062 [KOG2250] Glutamate/leucine/phenylalanine/valine dehydrogenases; [GO:0055114] oxidation-reduction process; [PTHR11606] GLUTAMATE DEHYDROGENASE; [GO:0016491] oxidoreductase activity; [PF00208] Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; [K00262] glutamate dehydrogenase (NADP+) [EC:1.4.1.4]; [GO:0006520] cellular amino acid metabolic process; [PTHR11606:SF4] SUBFAMILY NOT NAMED; [1.4.1.4] Glutamate dehydrogenase (NADP(+)).; [PF02812] Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 42.74 0.7584 28 Mapoly0103s0063 [PTHR21419] FAMILY NOT NAMED; [PF13517] Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 42.78 0.6517 29 Mapoly0001s0266 [GO:0003677] DNA binding; [PF01192] RNA polymerase Rpb6; [KOG3405] RNA polymerase subunit K; [PTHR10773] DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2; [GO:0006351] transcription, DNA-dependent; [GO:0003899] DNA-directed RNA polymerase activity; [K03014] DNA-directed RNA polymerases I, II, and III subunit RPABC2 43.16 0.7553 30 Mapoly0059s0079 [KOG2014] SMT3/SUMO-activating complex, AOS1/RAD31 component; [PF00899] ThiF family; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [K10684] ubiquitin-like 1-activating enzyme E1 A [EC:6.3.2.19] 43.59 0.7670 31 Mapoly0006s0255 [GO:0003723] RNA binding; [PTHR10288] KH DOMAIN CONTAINING RNA BINDING PROTEIN; [PF00013] KH domain; [KOG2192] PolyC-binding hnRNP-K protein HRB57A/hnRNP, contains KH domain; [K13210] far upstream element-binding protein 44.00 0.7559 32 Mapoly0185s0017 [GO:0030915] Smc5-Smc6 complex; [PF08746] RING-like domain; [KOG4718] Non-SMC (structural maintenance of chromosomes) element 1 protein (NSE1); [PTHR20973] NON-SMC ELEMENT 1-RELATED; [PF07574] Nse1 non-SMC component of SMC5-6 complex; [GO:0006281] DNA repair; [PTHR20973:SF0] SUBFAMILY NOT NAMED 46.99 0.7544 33 Mapoly0144s0027 [PTHR12872] ALPHA-N-ACETYLGLUCOSAMINIDASE; [KOG2233] Alpha-N-acetylglucosaminidase; [PF05089] Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain; [K01205] alpha-N-acetylglucosaminidase [EC:3.2.1.50]; [3.2.1.50] Alpha-N-acetylglucosaminidase.; [PF12972] Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain; [PF12971] Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain 47.35 0.7364 34 Mapoly0014s0097 [PF13414] TPR repeat; [KOG1308] Hsp70-interacting protein Hip/Transient component of progesterone receptor complexes and an Hsp70-binding protein; [PTHR22904:SF34] HSC70-INTERACTING PROTEIN; [PTHR22904] TPR REPEAT CONTAINING PROTEIN 47.56 0.7521 35 Mapoly0086s0078 [GO:0003677] DNA binding; [GO:0006275] regulation of DNA replication; [GO:0030337] DNA polymerase processivity factor activity; [PTHR11352] PROLIFERATING CELL NUCLEAR ANTIGEN; [PF00705] Proliferating cell nuclear antigen, N-terminal domain; [KOG1636] DNA polymerase delta processivity factor (proliferating cell nuclear antigen); [PF02747] Proliferating cell nuclear antigen, C-terminal domain 47.57 0.7456 36 Mapoly0045s0049 - 50.42 0.7121 37 Mapoly0061s0107 [GO:0003677] DNA binding; [KOG0483] Transcription factor HEX, contains HOX and HALZ domains; [PF00046] Homeobox domain; [PF08670] MEKHLA domain; [PF01852] START domain; [PTHR24326] FAMILY NOT NAMED; [GO:0008289] lipid binding; [K09338] homeobox-leucine zipper protein 50.83 0.7070 38 Mapoly0049s0118 [PTHR32002] FAMILY NOT NAMED; [PF02042] RWP-RK domain 51.30 0.7162 39 Mapoly0135s0035 [GO:0003676] nucleic acid binding; [PF02037] SAP domain 52.65 0.7469 40 Mapoly0021s0043 - 52.80 0.7437 41 Mapoly0001s0064 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [GO:0008173] RNA methyltransferase activity; [PTHR12029] RNA METHYLTRANSFERASE; [KOG0838] RNA Methylase, SpoU family; [PF00588] SpoU rRNA Methylase family 54.92 0.7467 42 Mapoly0002s0237 [PTHR12864] RAN BINDING PROTEIN 9-RELATED; [PF10607] CTLH/CRA C-terminal to LisH motif domain; [GO:0005515] protein binding; [KOG1477] SPRY domain-containing proteins; [PTHR12864:SF1] RAN BINDING PROTEIN 9-RELATED; [PF00622] SPRY domain 56.57 0.6781 43 Mapoly0005s0130 [GO:0042393] histone binding; [PF02182] SAD/SRA domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF13923] Zinc finger, C3HC4 type (RING finger); [PTHR14140] E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED 63.95 0.7274 44 Mapoly0069s0082 [PTHR23002] ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding 63.99 0.7337 45 Mapoly0044s0136 [PF12171] Zinc-finger double-stranded RNA-binding; [K13104] zinc finger protein 830; [PTHR13278] UNCHARACTERIZED; [KOG3032] Uncharacterized conserved protein 65.13 0.6463 46 Mapoly0014s0064 [PTHR10552] U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A; [K11092] U2 small nuclear ribonucleoprotein A'; [KOG1644] U2-associated snRNP A' protein; [PF14580] Leucine-rich repeat 66.23 0.7303 47 Mapoly0005s0256 [PF12220] U1 small nuclear ribonucleoprotein of 70kDa MW N terminal; [KOG0113] U1 small nuclear ribonucleoprotein (RRM superfamily); [PTHR13952:SF5] PREDICTED: HYPOTHETICAL PROTEIN, PARTIAL; [PTHR13952] U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD; [K11093] U1 small nuclear ribonucleoprotein 70kDa; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 67.87 0.7251 48 Mapoly0090s0070 [PF00169] PH domain 68.01 0.6787 49 Mapoly0013s0048 [KOG0381] HMG box-containing protein; [PF00505] HMG (high mobility group) box; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN 68.56 0.7527 50 Mapoly0043s0127 [GO:0031625] ubiquitin protein ligase binding; [GO:0031461] cullin-RING ubiquitin ligase complex; [GO:0006511] ubiquitin-dependent protein catabolic process; [K10609] cullin 4; [PF10557] Cullin protein neddylation domain; [PTHR11932] CULLIN; [PF00888] Cullin family; [KOG2167] Cullins; [PTHR11932:SF27] SUBFAMILY NOT NAMED 70.20 0.7087 51 Mapoly0036s0142 [GO:0003677] DNA binding; [KOG1757] Histone 2A; [K11251] histone H2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 71.24 0.7394 52 Mapoly0087s0021 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [KOG0969] DNA polymerase delta, catalytic subunit; [PTHR10322:SF11] DNA POLYMERASE DELTA CATALYTIC SUBUNIT; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [K02327] DNA polymerase delta subunit 1 [EC:2.7.7.7]; [PF14260] C4-type zinc-finger of DNA polymerase delta; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT 71.41 0.7242 53 Mapoly0087s0074 [GO:0005685] U1 snRNP; [PF06220] U1 zinc finger; [GO:0008270] zinc ion binding; [GO:0000398] mRNA splicing, via spliceosome; [KOG3454] U1 snRNP-specific protein C; [GO:0000387] spliceosomal snRNP assembly; [PTHR31148] FAMILY NOT NAMED 74.95 0.7318 54 Mapoly0001s0197 [K10733] GINS complex subunit 2; [GO:0006260] DNA replication; [PF05916] GINS complex protein; [GO:0005634] nucleus; [KOG4071] Uncharacterized conserved protein; [PTHR12772] DNA REPLICATION COMPLEX GINS PROTEIN PSF2 76.75 0.6931 55 Mapoly0070s0095 [PTHR23215] ZINC FINGER PROTEIN 207; [KOG2893] Zn finger protein 77.07 0.7179 56 Mapoly0051s0073 [PF14675] FANCI solenoid 1; [PTHR21818:SF0] SUBFAMILY NOT NAMED; [PF14680] FANCI helical domain 2; [KOG4553] Uncharacterized conserved protein; [K10895] fanconi anemia group I protein; [PF14679] FANCI helical domain 1; [GO:0006281] DNA repair; [PF14678] FANCI solenoid 4; [PTHR21818] BC025462 PROTEIN; [PF14676] FANCI solenoid 2 79.37 0.7308 57 Mapoly0152s0004 [PTHR12460] CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN; [PTHR12460:SF4] SUBFAMILY NOT NAMED; [PF04818] RNA polymerase II-binding domain.; [KOG2669] Regulator of nuclear mRNA 81.39 0.7183 58 Mapoly0013s0011 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 81.98 0.7264 59 Mapoly0001s0457 [PTHR14360:SF1] UNCHARACTERIZED; [PF07798] Protein of unknown function (DUF1640); [KOG3156] Uncharacterized membrane protein; [PTHR14360] UNCHARACTERIZED 82.65 0.6919 60 Mapoly0090s0046 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [K11251] histone H2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 83.11 0.7296 61 Mapoly0051s0078 [GO:0006355] regulation of transcription, DNA-dependent; [KOG0266] WD40 repeat-containing protein; [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [PF00400] WD domain, G-beta repeat 83.25 0.7080 62 Mapoly0021s0138 [KOG1548] Transcription elongation factor TAT-SF1; [GO:0005515] protein binding; [K13093] HIV Tat-specific factor 1; [PF02213] GYF domain; [PTHR15608] SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2; [PF14237] Domain of unknown function (DUF4339); [GO:0003676] nucleic acid binding; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 83.40 0.7081 63 Mapoly0011s0077 [PTHR23419:SF0] SUBFAMILY NOT NAMED; [KOG3338] Divalent cation tolerance-related protein; [GO:0010038] response to metal ion; [PF03091] CutA1 divalent ion tolerance protein; [K03926] periplasmic divalent cation tolerance protein; [PTHR23419] DIVALENT CATION TOLERANCE CUTA-RELATED 84.14 0.7335 64 Mapoly0074s0069 - 84.14 0.6824 65 Mapoly0084s0054 [K03029] 26S proteasome regulatory subunit N10; [PF02809] Ubiquitin interaction motif; [PF13519] von Willebrand factor type A domain; [GO:0006511] ubiquitin-dependent protein catabolic process; [PTHR10223] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4; [GO:0008540] proteasome regulatory particle, base subcomplex; [KOG2884] 26S proteasome regulatory complex, subunit RPN10/PSMD4 85.21 0.7171 66 Mapoly0033s0129 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0003910] DNA ligase (ATP) activity; [PF04679] ATP dependent DNA ligase C terminal region; [PTHR10459] DNA LIGASE; [K10747] DNA ligase 1 [EC:6.5.1.1]; [PF01068] ATP dependent DNA ligase domain; [6.5.1.1] DNA ligase (ATP).; [GO:0006281] DNA repair; [PF04675] DNA ligase N terminus; [PTHR10459:SF10] DNA LIGASE I; [GO:0006310] DNA recombination; [KOG0967] ATP-dependent DNA ligase I 85.49 0.6971 67 Mapoly0005s0267 [PTHR23111] ZINC FINGER PROTEIN; [GO:0008270] zinc ion binding; [PF00641] Zn-finger in Ran binding protein and others 86.23 0.7184 68 Mapoly0011s0083 [PTHR10997] IMPORTIN-7, 8, 11 86.69 0.7294 69 Mapoly0159s0020 [K05544] tRNA-dihydrouridine synthase 3 [EC:1.-.-.-]; [GO:0050660] flavin adenine dinucleotide binding; [GO:0055114] oxidation-reduction process; [PTHR11082:SF8] TRNA-DIHYDROURIDINE SYNTHASE 3; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PF01207] Dihydrouridine synthase (Dus); [KOG2333] Uncharacterized conserved protein; [GO:0008033] tRNA processing; [PTHR11082] TRNA-DIHYDROURIDINE SYNTHASE; [GO:0046872] metal ion binding; [GO:0017150] tRNA dihydrouridine synthase activity; [1.-.-.-] Oxidoreductases. 87.97 0.7043 70 Mapoly0012s0100 [PF01564] Spermine/spermidine synthase; [PTHR11558] SPERMIDINE/SPERMINE SYNTHASE; [KOG1562] Spermidine synthase; [2.5.1.16] Spermidine synthase.; [GO:0003824] catalytic activity; [K00797] spermidine synthase [EC:2.5.1.16] 89.33 0.6497 71 Mapoly0116s0028 [PTHR23074:SF19] KATANIN-RELATED; [GO:0005524] ATP binding; [3.6.4.3] Microtubule-severing ATPase.; [K07767] microtubule-severing ATPase [EC:3.6.4.3]; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0738] AAA+-type ATPase; [PTHR23074] AAA ATPASE; [PF09336] Vps4 C terminal oligomerisation domain 91.19 0.6989 72 Mapoly0002s0217 [PF00183] Hsp90 protein; [GO:0005524] ATP binding; [GO:0006950] response to stress; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [GO:0006457] protein folding; [K04079] molecular chaperone HtpG; [PTHR11528] HEAT SHOCK PROTEIN 90; [KOG0019] Molecular chaperone (HSP90 family); [GO:0051082] unfolded protein binding 92.34 0.6564 73 Mapoly0146s0045 [GO:0003723] RNA binding; [PTHR11207:SF1] RIBONUCLEASE III; [PF00035] Double-stranded RNA binding motif; [GO:0004525] ribonuclease III activity; [GO:0016075] rRNA catabolic process; [PTHR11207] RIBONUCLEASE III 92.56 0.7219 74 Mapoly0101s0048 [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat 92.75 0.7288 75 Mapoly0014s0217 [GO:0005515] protein binding; [KOG0322] G-protein beta subunit-like protein GNB1L, contains WD repeats; [PTHR19854:SF1] GB DEF: GUANINE NUCLEOTIDE-BINDING PROTEIN BETA SUBUNIT-LIKE PROTEIN 1 G PROTEIN BETA-S; [PTHR19854] TRANSDUCIN BETA-LIKE 3; [PF00400] WD domain, G-beta repeat 93.45 0.6800 76 Mapoly0013s0016 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR31614] FAMILY NOT NAMED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08661] Replication factor A protein 3; [GO:0006310] DNA recombination 95.50 0.7161 77 Mapoly0058s0098 - 97.02 0.6033 78 Mapoly0151s0042 [PTHR31500:SF0] SUBFAMILY NOT NAMED; [PF03479] Domain of unknown function (DUF296); [PTHR31500] FAMILY NOT NAMED 97.40 0.6936 79 Mapoly0115s0039 [KOG1780] Small Nuclear ribonucleoprotein G; [K11099] small nuclear ribonucleoprotein G; [PF01423] LSM domain; [PTHR10553] SMALL NUCLEAR RIBONUCLEOPROTEIN 97.52 0.7457 80 Mapoly0033s0073 [PTHR10984:SF2] THIOREDOXIN-RELATED; [GO:0045454] cell redox homeostasis; [PTHR10984] ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN; [PF13850] Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC); [KOG2667] COPII vesicle protein; [PF00085] Thioredoxin; [PF07970] Endoplasmic reticulum vesicle transporter 99.49 0.6897 81 Mapoly0063s0041 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR23340] ARGININE/SERINE RICH SPLICING FACTOR SF4/14; [PF01585] G-patch domain; [GO:0003676] nucleic acid binding; [PF01805] Surp module 100.95 0.7015 82 Mapoly0028s0110 [GO:0005524] ATP binding; [PTHR23069] TAT-BINDING HOMOLOG 7; [PTHR23069:SF0] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [PF00439] Bromodomain; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0732] AAA+-type ATPase containing the bromodomain 102.13 0.7128 83 Mapoly0028s0075 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [K11251] histone H2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 102.53 0.7382 84 Mapoly0113s0030 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [K14440] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:3.6.4.12]; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [3.6.4.12] DNA helicase.; [KOG1000] Chromatin remodeling protein HARP/SMARCAL1, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF43] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A-LIKE PROTEIN 1 103.56 0.6619 85 Mapoly0019s0051 [GO:0003723] RNA binding; [PTHR23270] PROGRAMMED CELL DEATH PROTEIN 11 (PRE-RRNA PROCESSING PROTEIN RRP5); [GO:0006397] mRNA processing; [GO:0005634] nucleus; [PF00575] S1 RNA binding domain; [KOG1070] rRNA processing protein Rrp5; [PF05843] Suppressor of forked protein (Suf) 104.18 0.6765 86 Mapoly0066s0106 [PTHR15588] LSM1; [KOG1784] Small Nuclear ribonucleoprotein splicing factor; [K12627] U6 snRNA-associated Sm-like protein LSm8; [PF01423] LSM domain 106.43 0.6926 87 Mapoly0033s0156 [KOG0266] WD40 repeat-containing protein; [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [PF00400] WD domain, G-beta repeat 107.08 0.6924 88 Mapoly0084s0045 [PF07719] Tetratricopeptide repeat; [KOG1211] Amidases; [PF13414] TPR repeat; [PTHR11895] AMIDASE; [GO:0016884] carbon-nitrogen ligase activity, with glutamine as amido-N-donor; [PTHR11895:SF6] AMIDASE; [PF01425] Amidase 108.80 0.6768 89 Mapoly0057s0080 [PTHR15140:SF6] SUBFAMILY NOT NAMED; [KOG3207] Beta-tubulin folding cofactor E; [PF01302] CAP-Gly domain; [PTHR15140] TUBULIN-SPECIFIC CHAPERONE E 108.89 0.6876 90 Mapoly0029s0049 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0016602] CCAAT-binding factor complex; [KOG1657] CCAAT-binding factor, subunit C (HAP5); [GO:0043565] sequence-specific DNA binding; [PF00808] Histone-like transcription factor (CBF/NF-Y) and archaeal histone; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PTHR10252:SF8] TRANSCRIPTIONAL ACTIVATOR HAP5; [GO:0005622] intracellular; [PTHR10252] HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED 109.09 0.7058 91 Mapoly0024s0072 [KOG0005] Ubiquitin-like protein; [GO:0005515] protein binding; [PF00240] Ubiquitin family; [PTHR10666] UBIQUITIN; [K08770] ubiquitin C 111.27 0.7001 92 Mapoly0174s0020 [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PF13086] AAA domain; [PF13087] AAA domain; [KOG1801] tRNA-splicing endonuclease positive effector (SEN1) 113.12 0.7074 93 Mapoly0125s0028 [GO:0000166] nucleotide binding; [PF00702] haloacid dehalogenase-like hydrolase; [KOG0205] Plasma membrane H+-transporting ATPase; [PTHR24093] FAMILY NOT NAMED; [PF00690] Cation transporter/ATPase, N-terminus; [GO:0046872] metal ion binding; [PF00122] E1-E2 ATPase 114.13 0.7017 94 Mapoly0051s0085 [KOG2267] Eukaryotic-type DNA primase, large subunit; [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10537] DNA PRIMASE LARGE SUBUNIT; [K02685] DNA primase large subunit [EC:2.7.7.-]; [PF04104] Eukaryotic and archaeal DNA primase, large subunit; [2.7.7.-] Nucleotidyltransferases. 114.20 0.7090 95 Mapoly0081s0083 [GO:0005524] ATP binding; [PTHR24054] CASEIN KINASE II SUBUNIT ALPHA; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K03097] casein kinase II subunit alpha [EC:2.7.11.1]; [GO:0006468] protein phosphorylation; [KOG0668] Casein kinase II, alpha subunit 114.68 0.6733 96 Mapoly0104s0042 [PTHR22846:SF2] TRANSDUCIN BETA-LIKE 1; [GO:0005515] protein binding; [PTHR22846] WD40 REPEAT PROTEIN; [KOG0273] Beta-transducin family (WD-40 repeat) protein; [PF08513] LisH; [PF00400] WD domain, G-beta repeat 115.24 0.7012 97 Mapoly0095s0052 [PF08839] DNA replication factor CDT1 like 115.72 0.7044 98 Mapoly0013s0062 [GO:0003677] DNA binding; [PTHR15348:SF0] SUBFAMILY NOT NAMED; [PF01388] ARID/BRIGHT DNA binding domain; [GO:0005622] intracellular; [PTHR15348] AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN (ARID DOMAIN- CONTAINING PROTEIN) (DEAD RINGER PROTEIN) (B-CELL REGULATOR OF IGH TRANSCRIPTION) (BRIGHT) 116.08 0.7030 99 Mapoly0161s0023 [PTHR16119] FAMILY NOT NAMED; [PF07857] CEO family (DUF1632) 117.05 0.6275 100 Mapoly0023s0062 [K11086] small nuclear ribonucleoprotein B and B'; [PTHR10701] SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N; [KOG3168] U1 snRNP component; [PF01423] LSM domain 117.49 0.6863 101 Mapoly0065s0033 [GO:0003723] RNA binding; [3.1.26.5] Ribonuclease P.; [K03538] ribonuclease P protein subunit POP4 [EC:3.1.26.5]; [GO:0000172] ribonuclease MRP complex; [PF01868] Domain of unknown function UPF0086; [PTHR13348] RIBONUCLEASE P; [GO:0006364] rRNA processing; [GO:0008033] tRNA processing; [GO:0030677] ribonuclease P complex; [GO:0006379] mRNA cleavage; [KOG4046] RNase MRP and P, subunit POP4/p29; [GO:0004540] ribonuclease activity 119.76 0.6718 102 Mapoly0046s0091 [GO:0000278] mitotic cell cycle; [PTHR22870] REGULATOR OF CHROMOSOME CONDENSATION; [KOG1427] Uncharacterized conserved protein, contains RCC1 domain; [PF00415] Regulator of chromosome condensation (RCC1) repeat; [GO:0051301] cell division; [GO:0007032] endosome organization 119.84 0.6973 103 Mapoly0034s0111 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 120.23 0.7138 104 Mapoly0009s0203 - 120.42 0.6829 105 Mapoly0007s0227 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02212] minichromosome maintenance protein 4 (cell division control protein 54); [KOG0478] DNA replication licensing factor, MCM4 component; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 123.21 0.7138 106 Mapoly0154s0022 [GO:0003723] RNA binding; [GO:0016787] hydrolase activity; [PTHR23114] FAMILY NOT NAMED; [PF05026] Dcp2, box A domain; [GO:0030145] manganese ion binding; [PTHR23114:SF9] SUBFAMILY NOT NAMED; [3.-.-.-] Hydrolases.; [KOG2839] Diadenosine and diphosphoinositol polyphosphate phosphohydrolase; [PF00293] NUDIX domain; [K12613] mRNA-decapping enzyme subunit 2 [EC:3.-.-.-] 123.25 0.6674 107 Mapoly0086s0053 - 123.39 0.6461 108 Mapoly0054s0038 [3.4.11.9] Xaa-Pro aminopeptidase.; [GO:0016787] hydrolase activity; [K01262] Xaa-Pro aminopeptidase [EC:3.4.11.9]; [PF00557] Metallopeptidase family M24; [KOG2413] Xaa-Pro aminopeptidase; [PF01321] Creatinase/Prolidase N-terminal domain; [PTHR10804] PROTEASE FAMILY M24 (METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P) 124.06 0.6956 109 Mapoly0002s0007 [GO:0003723] RNA binding; [GO:0001522] pseudouridine synthesis; [GO:0009451] RNA modification; [GO:0009982] pseudouridine synthase activity; [PF00849] RNA pseudouridylate synthase; [PTHR21600] RIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE SYNTHASE B; [PF01479] S4 domain 124.06 0.6450 110 Mapoly0001s0208 [PTHR31431] FAMILY NOT NAMED; [KOG4833] Uncharacterized conserved protein; [K14311] nuclear pore complex protein Nup188; [PF10487] Nucleoporin subcomplex protein binding to Pom34 125.91 0.6990 111 Mapoly0071s0007 [GO:0005524] ATP binding; [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family; [K09494] T-complex protein 1 subunit beta; [KOG0363] Chaperonin complex component, TCP-1 beta subunit (CCT2) 127.61 0.6945 112 Mapoly0042s0032 [PF13259] Protein of unknown function (DUF4050) 128.45 0.7035 113 Mapoly0052s0086 [PF05641] Agenet domain; [PTHR31917] FAMILY NOT NAMED 129.32 0.7036 114 Mapoly0061s0032 [GO:0016020] membrane; [PF07933] Protein of unknown function (DUF1681); [PTHR12847:SF4] SUBFAMILY NOT NAMED; [KOG2500] Uncharacterized conserved protein; [GO:0006897] endocytosis; [PTHR12847] ATP-BINDING CASSETTE (ABC) TRANSPORTER-RELATED 129.34 0.6734 115 Mapoly0061s0010 [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10536] DNA PRIMASE SMALL SUBUNIT; [KOG2851] Eukaryotic-type DNA primase, catalytic (small) subunit; [K02684] DNA primase small subunit [EC:2.7.7.-]; [2.7.7.-] Nucleotidyltransferases.; [PF01896] Eukaryotic and archaeal DNA primase small subunit 129.72 0.7048 116 Mapoly0007s0156 [PTHR31745] FAMILY NOT NAMED; [PF08536] Whirly transcription factor 130.45 0.6815 117 Mapoly0083s0043 [GO:0008375] acetylglucosaminyltransferase activity; [GO:0016020] membrane; [PF02485] Core-2/I-Branching enzyme; [PTHR31042] FAMILY NOT NAMED 132.33 0.6968 118 Mapoly0083s0062 [K09553] stress-induced-phosphoprotein 1; [GO:0005515] protein binding; [PF13414] TPR repeat; [KOG0548] Molecular co-chaperone STI1; [PF00515] Tetratricopeptide repeat; [PTHR22904] TPR REPEAT CONTAINING PROTEIN 132.58 0.6499 119 Mapoly0007s0143 [KOG2235] Uncharacterized conserved protein; [PTHR31057] FAMILY NOT NAMED; [PF09743] Uncharacterized conserved protein (DUF2042); [PTHR31057:SF0] SUBFAMILY NOT NAMED 132.65 0.6688 120 Mapoly0078s0038 [GO:0031072] heat shock protein binding; [KOG0712] Molecular chaperone (DnaJ superfamily); [PTHR24076:SF1] SUBFAMILY NOT NAMED; [PF00226] DnaJ domain; [PF01556] DnaJ C terminal domain; [PTHR24076] FAMILY NOT NAMED; [PF00684] DnaJ central domain; [GO:0051082] unfolded protein binding 134.34 0.6492 121 Mapoly0030s0061 [GO:0005663] DNA replication factor C complex; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [GO:0003689] DNA clamp loader activity; [PF00533] BRCA1 C Terminus (BRCT) domain; [K10754] replication factor C subunit 1; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08519] Replication factor RFC1 C terminal domain; [KOG1968] Replication factor C, subunit RFC1 (large subunit) 135.10 0.6863 122 Mapoly0042s0007 [GO:0003677] DNA binding; [K02213] cell division control protein 6; [KOG2227] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase; [PF13401] AAA domain; [PF01429] Methyl-CpG binding domain; [GO:0005634] nucleus; [PF09079] CDC6, C terminal; [PTHR10763] CELL DIVISION CONTROL PROTEIN 6-RELATED 135.39 0.6934 123 Mapoly0010s0048 - 136.44 0.6977 124 Mapoly0006s0287 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02209] minichromosome maintenance protein 5 (cell division control protein 46); [PTHR11630:SF42] DNA REPLICATION LICENSING FACTOR MCM5; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain; [KOG0481] DNA replication licensing factor, MCM5 component 139.48 0.7032 125 Mapoly0218s0012 [PTHR15744:SF0] SUBFAMILY NOT NAMED; [PTHR15744] BLOM7 141.00 0.6726 126 Mapoly0032s0097 [PF13837] Myb/SANT-like DNA-binding domain 141.03 0.6479 127 Mapoly0027s0185 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF39] CDC2-RELATED PROTEIN KINASE; [KOG0600] Cdc2-related protein kinase; [K08819] Cdc2-related kinase, arginine/serine-rich [EC:2.7.11.22]; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 141.99 0.6870 128 Mapoly0001s0195 [GO:0070985] TFIIK complex; [GO:0006355] regulation of transcription, DNA-dependent; [GO:0016538] cyclin-dependent protein serine/threonine kinase regulator activity; [GO:0019901] protein kinase binding; [PTHR10026:SF8] CYCLIN H; [PF00134] Cyclin, N-terminal domain; [PTHR10026] CYCLIN; [KOG2496] Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, cyclin H subunit; [GO:0006351] transcription, DNA-dependent; [GO:0000079] regulation of cyclin-dependent protein serine/threonine kinase activity 142.39 0.6410 129 Mapoly0071s0008 [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [KOG0107] Alternative splicing factor SRp20/9G8 (RRM superfamily); [GO:0003676] nucleic acid binding; [PTHR10548] SPLICING FACTOR, ARGININE/SERINE-RICH; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 143.04 0.6858 130 Mapoly0038s0098 [K03351] anaphase-promoting complex subunit 4; [PF12896] Anaphase-promoting complex, cyclosome, subunit 4; [KOG4640] Anaphase-promoting complex (APC), subunit 4; [GO:0030071] regulation of mitotic metaphase/anaphase transition; [PF12894] Anaphase-promoting complex subunit 4 WD40 domain; [PTHR13260] ANAPHASE PROMOTING COMPLEX SUBUNIT 4 (APC4) (CYCLOSOME SUBUNIT 4); [GO:0005680] anaphase-promoting complex; [GO:0031145] anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 143.59 0.6606 131 Mapoly0101s0047 [KOG2084] Predicted histone tail methylase containing SET domain; [GO:0005515] protein binding; [PF00856] SET domain; [K11426] SET and MYND domain-containing protein; [PTHR12197] SET AND MYND DOMAIN CONTAINING; [PF01753] MYND finger 144.20 0.5600 132 Mapoly0001s0009 [PTHR10540:SF7] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7; [GO:0005515] protein binding; [PF13012] Maintenance of mitochondrial structure and function; [PTHR10540] EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED; [PF01398] JAB1/Mov34/MPN/PAD-1 ubiquitin protease; [KOG1556] 26S proteasome regulatory complex, subunit RPN8/PSMD7; [K03038] 26S proteasome regulatory subunit N8 145.78 0.7064 133 Mapoly0046s0087 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PTHR24420:SF145] SUBFAMILY NOT NAMED; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 147.75 0.6205 134 Mapoly0113s0037 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [KOG2577] Transcription factor E2F/dimerization partner (TDP); [PTHR12081] TRANSCRIPTION FACTOR E2F 148.31 0.6825 135 Mapoly0011s0132 - 148.79 0.6774 136 Mapoly0111s0035 [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PTHR12547] CCCH ZINC FINGER/TIS11-RELATED; [GO:0046872] metal ion binding; [KOG1677] CCCH-type Zn-finger protein 149.49 0.6701 137 Mapoly0029s0121 [K11550] kinetochore protein Spc25, animal type; [PF08234] Chromosome segregation protein Spc25; [PTHR14281] FAMILY NOT NAMED 150.23 0.6954 138 Mapoly0011s0080 [KOG2315] Predicted translation initiation factor related to eIF-3a; [PTHR13227] NUCLEASE-RELATED; [PF08662] Eukaryotic translation initiation factor eIF2A 155.07 0.6715 139 Mapoly0133s0052 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K08851] TP53 regulating kinase [EC:2.7.11.1]; [PTHR12209] O-SIALOGLYCOPROTEIN ENDOPEPTIDASE; [GO:0006468] protein phosphorylation; [KOG3087] Serine/threonine protein kinase; [GO:0004674] protein serine/threonine kinase activity 156.20 0.6905 140 Mapoly0014s0155 [PF08321] PPP5 TPR repeat region; [GO:0005737] cytoplasm; [PTHR11668] SERINE/THREONINE PROTEIN PHOSPHATASE; [PF00149] Calcineurin-like phosphoesterase; [GO:0005515] protein binding; [GO:0016787] hydrolase activity; [PF13414] TPR repeat; [GO:0004721] phosphoprotein phosphatase activity; [GO:0006470] protein dephosphorylation; [GO:0005634] nucleus; [PTHR11668:SF12] PROTEIN PHOSPHATASE-5; [PF00515] Tetratricopeptide repeat; [KOG0376] Serine-threonine phosphatase 2A, catalytic subunit; [3.1.3.16] Phosphoprotein phosphatase.; [K04460] protein phosphatase 5 [EC:3.1.3.16] 156.32 0.6701 141 Mapoly0054s0063 [PTHR24012] FAMILY NOT NAMED; [KOG0107] Alternative splicing factor SRp20/9G8 (RRM superfamily); [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 156.66 0.6313 142 Mapoly0062s0108 [GO:0005524] ATP binding; [2.7.11.26] [Tau protein] kinase.; [PF00069] Protein kinase domain; [KOG0658] Glycogen synthase kinase-3; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24057] GLYCOGEN SYNTHASE KINASE-3 ALPHA; [K03083] glycogen synthase kinase 3 beta [EC:2.7.11.26] 158.04 0.6733 143 Mapoly0077s0024 [PTHR21596] RIBONUCLEASE P PROTEIN SUBUNIT P38-RELATED 158.46 0.6510 144 Mapoly0001s0378 [PTHR32086] FAMILY NOT NAMED; [K10891] fanconi anemia group D2 protein; [GO:0006281] DNA repair; [KOG4712] Uncharacterized conserved protein; [PF14631] Fanconi anaemia protein FancD2 nuclease 158.83 0.6869 145 Mapoly0120s0004 [PF00488] MutS domain V; [GO:0005524] ATP binding; [K08735] DNA mismatch repair protein MSH2; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PTHR11361:SF35] MUTS HOMOLOG 2, MSH2; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III; [KOG0219] Mismatch repair ATPase MSH2 (MutS family); [PF05190] MutS family domain IV 161.74 0.6859 146 Mapoly0083s0001 [GO:0008168] methyltransferase activity; [PF05891] AdoMet dependent proline di-methyltransferase; [PTHR12753] AD-003 - RELATED 161.89 0.6523 147 Mapoly0028s0032 [GO:0003755] peptidyl-prolyl cis-trans isomerase activity; [PTHR11071] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [K12733] peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]; [PF00160] Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; [GO:0000413] protein peptidyl-prolyl isomerization; [GO:0006457] protein folding; [5.2.1.8] Peptidylprolyl isomerase.; [KOG0881] Cyclophilin type peptidyl-prolyl cis-trans isomerase 162.11 0.6533 148 Mapoly0059s0005 [GO:0016020] membrane; [PF00072] Response regulator receiver domain; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [GO:0000160] phosphorelay signal transduction system; [KOG0519] Sensory transduction histidine kinase; [GO:0007165] signal transduction; [PTHR24423] TWO-COMPONENT SENSOR HISTIDINE KINASE; [PF05231] MASE1; [PF00512] His Kinase A (phospho-acceptor) domain; [GO:0000155] phosphorelay sensor kinase activity 165.39 0.6486 149 Mapoly0005s0080 [GO:0006355] regulation of transcription, DNA-dependent; [KOG0794] CDK8 kinase-activating protein cyclin C; [GO:0019901] protein kinase binding; [PF00134] Cyclin, N-terminal domain; [PTHR10026] CYCLIN; [GO:0000079] regulation of cyclin-dependent protein serine/threonine kinase activity 165.63 0.6423 150 Mapoly0080s0073 [GO:0005524] ATP binding; [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [GO:0003676] nucleic acid binding; [KOG0922] DEAH-box RNA helicase; [GO:0046872] metal ion binding; [PF10354] Domain of unknown function (DUF2431) 166.11 0.6405 151 Mapoly0073s0081 [K11876] proteasome assembly chaperone 2; [KOG3112] Uncharacterized conserved protein; [PF09754] PAC2 family; [PTHR12970] TUMOR NECROSIS FACTOR SUPERFAMILY, MEMBER 5-INDUCED PROTEIN 1 (CLAST3) 166.39 0.6785 152 Mapoly0132s0046 [PF00855] PWWP domain; [PTHR12550] HEPATOMA-DERIVED GROWTH FACTOR-RELATED; [PTHR12550:SF5] UNCHARACTERIZED 167.23 0.6669 153 Mapoly0030s0111 - 167.96 0.5118 154 Mapoly0064s0055 [PF13656] RNA polymerase Rpb3/Rpb11 dimerisation domain; [K03008] DNA-directed RNA polymerase II subunit RPB11; [PTHR13946] DNA-DIRECTED RNA POLYMERASE I,II,III; [KOG4392] RNA polymerase, subunit L 169.02 0.6965 155 Mapoly0022s0041 [GO:0003723] RNA binding; [KOG2190] PolyC-binding proteins alphaCP-1 and related KH domain proteins; [PTHR10288] KH DOMAIN CONTAINING RNA BINDING PROTEIN; [PF00013] KH domain 169.60 0.6719 156 Mapoly0028s0103 [PF01713] Smr domain; [GO:0003677] DNA binding; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K07456] DNA mismatch repair protein MutS2; [GO:0016887] ATPase activity; [PTHR11361:SF14] DNA MISMATCH REPAIR PROTEIN MUTS2; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [GO:0045910] negative regulation of DNA recombination 169.78 0.5928 157 Mapoly0038s0101 [K12837] splicing factor U2AF 65 kDa subunit; [PTHR23139] RNA-BINDING PROTEIN; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG0120] Splicing factor U2AF, large subunit (RRM superfamily); [GO:0003676] nucleic acid binding; [PTHR23139:SF9] SPLICING FACTOR U2AF LARGE SUBUNIT; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 170.04 0.6801 158 Mapoly0054s0054 [KOG3276] Uncharacterized conserved protein, contains YggU domain; [PTHR13420:SF1] gb def: y66d12a.8.p [caenorhabditis elegans]; [K09131] hypothetical protein; [PTHR13420] UNCHARACTERIZED; [PF02594] Uncharacterised ACR, YggU family COG1872 170.15 0.5555 159 Mapoly0105s0015 [GO:0003677] DNA binding; [KOG2393] Transcription initiation factor IIF, large subunit (RAP74); [GO:0032968] positive regulation of transcription elongation from RNA polymerase II promoter; [K03138] transcription initiation factor TFIIF subunit alpha; [PF05793] Transcription initiation factor IIF, alpha subunit (TFIIF-alpha); [PTHR13011] TFIIF-ALPHA; [GO:0005634] nucleus; [GO:0006367] transcription initiation from RNA polymerase II promoter 170.29 0.6642 160 Mapoly0106s0044 [PF03980] Nnf1 172.12 0.6364 161 Mapoly0002s0271 - 172.43 0.6510 162 Mapoly0140s0033 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 172.62 0.6495 163 Mapoly0007s0066 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PTHR19306:SF1] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5 SMC5; [KOG0979] Structural maintenance of chromosome protein SMC5/Spr18, SMC superfamily; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0000724] double-strand break repair via homologous recombination 175.66 0.6857 164 Mapoly0099s0054 [GO:0035064] methylated histone residue binding; [PTHR10333] INHIBITOR OF GROWTH PROTEIN; [PF12998] Inhibitor of growth proteins N-terminal histone-binding; [PF00628] PHD-finger; [GO:0005515] protein binding; [KOG1973] Chromatin remodeling protein, contains PHD Zn-finger; [GO:0016568] chromatin modification; [GO:0005634] nucleus 176.48 0.6533 165 Mapoly0105s0026 - 177.66 0.6608 166 Mapoly0001s0330 [PTHR11210] RING BOX; [PF12861] Anaphase-promoting complex subunit 11 RING-H2 finger; [K03358] anaphase-promoting complex subunit 11; [GO:0004842] ubiquitin-protein ligase activity; [GO:0005680] anaphase-promoting complex 178.02 0.6731 167 Mapoly0011s0134 - 178.66 0.6812 168 Mapoly0075s0022 [KOG0482] DNA replication licensing factor, MCM7 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [K02210] minichromosome maintenance protein 7 (cell division control protein 47); [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [PTHR11630:SF26] DNA REPLICATION LICENSING FACTOR MCM7 182.45 0.6835 169 Mapoly0103s0053 [GO:0008168] methyltransferase activity; [PTHR23068:SF3] gb def: Hypothetical protein T15N1_120; [PTHR23068] DNA (CYTOSINE-5-)-METHYLTRANSFERASE 3-RELATED; [PF00145] C-5 cytosine-specific DNA methylase 182.61 0.6329 170 Mapoly0052s0043 [K11098] small nuclear ribonucleoprotein F; [PTHR11021] SMALL NUCLEAR RIBONUCLEOPROTEIN F (SNRNP-F); [KOG3482] Small nuclear ribonucleoprotein (snRNP) SMF; [PF01423] LSM domain 183.34 0.7010 171 Mapoly0030s0009 [PF00505] HMG (high mobility group) box; [KOG0526] Nucleosome-binding factor SPN, POB3 subunit; [PF03531] Structure-specific recognition protein (SSRP1); [PTHR13711:SF39] SUBFAMILY NOT NAMED; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [PF08512] Histone chaperone Rttp106-like; [K09272] structure-specific recognition protein 1 185.96 0.6775 172 Mapoly0191s0002 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [K07374] tubulin alpha; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [KOG1376] Alpha tubulin; [GO:0005525] GTP binding 186.26 0.6707 173 Mapoly0024s0064 [PF07962] Replication Fork Protection Component Swi3; [GO:0008270] zinc ion binding; [PTHR13220] TIMELESS INTERACTING-RELATED; [PF00098] Zinc knuckle; [GO:0006974] response to DNA damage stimulus; [GO:0005634] nucleus; [GO:0048478] replication fork protection; [GO:0003676] nucleic acid binding; [GO:0007049] cell cycle 186.71 0.5920 174 Mapoly0041s0007 [GO:0016272] prefoldin complex; [PF02996] Prefoldin subunit; [KOG3048] Molecular chaperone Prefoldin, subunit 5; [GO:0006457] protein folding; [PTHR12674] PREFOLDIN SUBUNIT 5; [GO:0051082] unfolded protein binding; [K04797] prefoldin alpha subunit 186.86 0.6850 175 Mapoly0058s0108 [GO:0003677] DNA binding; [KOG0214] RNA polymerase II, second largest subunit; [PF04567] RNA polymerase Rpb2, domain 5; [PF04565] RNA polymerase Rpb2, domain 3; [PTHR20856] DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2; [PF00562] RNA polymerase Rpb2, domain 6; [PF04566] RNA polymerase Rpb2, domain 4; [GO:0032549] ribonucleoside binding; [PF04561] RNA polymerase Rpb2, domain 2; [GO:0006351] transcription, DNA-dependent; [GO:0003899] DNA-directed RNA polymerase activity; [PF04560] RNA polymerase Rpb2, domain 7; [PF04563] RNA polymerase beta subunit 188.04 0.6599 176 Mapoly0123s0035 [PTHR14614] HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; [PF10294] Putative methyltransferase; [KOG3201] Uncharacterized conserved protein 188.21 0.5896 177 Mapoly0012s0102 [PTHR23365] POLY-A BINDING PROTEIN 2; [K14396] polyadenylate-binding protein 2; [KOG4209] Splicing factor RNPS1, SR protein superfamily; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 190.26 0.6531 178 Mapoly0054s0064 [PF03178] CPSF A subunit region; [PF10433] Mono-functional DNA-alkylating methyl methanesulfonate N-term; [PTHR10644:SF3] DNA DAMAGE-BINDING PROTEIN 1 (DAMAGE-SPECIFIC DNA-BINDING PROTEIN 1)(UV-DAMAGED DNA-BINDING FACTOR); [K10610] DNA damage-binding protein 1; [GO:0005634] nucleus; [PTHR10644] DNA REPAIR/RNA PROCESSING CPSF FAMILY; [KOG1897] Damage-specific DNA binding complex, subunit DDB1; [GO:0003676] nucleic acid binding 190.52 0.6106 179 Mapoly0001s0149 [K11596] argonaute; [PF02170] PAZ domain; [PF08699] Domain of unknown function (DUF1785); [PTHR22891] EUKARYOTIC TRANSLATION INITIATION FACTOR 2C; [PF02171] Piwi domain; [GO:0005515] protein binding; [KOG1041] Translation initiation factor 2C (eIF-2C) and related proteins 194.22 0.6459 180 Mapoly0125s0043 [PTHR22601] ISP4 LIKE PROTEIN; [GO:0055085] transmembrane transport; [KOG2262] Sexual differentiation process protein ISP4; [PF03169] OPT oligopeptide transporter protein 194.32 0.6147 181 Mapoly0001s0273 [PTHR10501] U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B; [PTHR10501:SF0] SMALL NUCLEAR RIBONUCLEOPROTEIN; [GO:0000398] mRNA splicing, via spliceosome; [GO:0003676] nucleic acid binding; [GO:0017069] snRNA binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 194.52 0.6670 182 Mapoly0063s0059 [GO:0000812] Swr1 complex; [GO:0006338] chromatin remodeling; [GO:0006355] regulation of transcription, DNA-dependent; [GO:0031011] Ino80 complex; [PTHR11937:SF47] SUBFAMILY NOT NAMED; [GO:0035267] NuA4 histone acetyltransferase complex; [PF00022] Actin; [GO:0006281] DNA repair; [PTHR11937] ACTIN; [KOG0679] Actin-related protein - Arp4p/Act3p 195.08 0.6553 183 Mapoly0027s0144 [GO:0016272] prefoldin complex; [KOG3501] Molecular chaperone Prefoldin, subunit 1; [PTHR20903] PREFOLDIN SUBUNIT 1-RELATED; [GO:0006457] protein folding; [GO:0051082] unfolded protein binding; [PF01920] Prefoldin subunit 195.40 0.6617 184 Mapoly0005s0067 [PTHR15242:SF0] SUBFAMILY NOT NAMED; [PTHR15242] SPLICING FACTOR, ARGININE/SERINE-RICH 2,RNAP C-TERM INTERACTING PROTEIN; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 195.46 0.6735 185 Mapoly0056s0069 [PF00645] Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region; [GO:0003677] DNA binding; [PTHR12083] POLYNUCLEOTIDE KINASE- 3'-PHOSPHATASE; [PF08645] Polynucleotide kinase 3 phosphatase; [K08073] bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]; [3.1.3.32] Polynucleotide 3'-phosphatase.; [GO:0008270] zinc ion binding; [2.7.1.78] Polynucleotide 5'-hydroxyl-kinase. 195.96 0.6360 186 Mapoly0005s0021 [PF13266] Protein of unknown function (DUF4057); [PTHR31132] FAMILY NOT NAMED 197.99 0.6855 187 Mapoly0003s0247 [K12845] U4/U6 small nuclear ribonucleoprotein SNU13; [KOG3387] 60S ribosomal protein 15.5kD/SNU13, NHP2/L7A family (includes ribonuclease P subunit p38), involved in splicing; [PTHR23105] RIBOSOMAL PROTEIN L7AE FAMILY MEMBER; [PF01248] Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 200.28 0.6513 188 Mapoly0014s0106 [KOG3172] Small nuclear ribonucleoprotein Sm D3; [PTHR23338] SMALL NUCLEAR RIBONUCLEOPROTEIN SM; [PF01423] LSM domain 201.11 0.6787 189 Mapoly0019s0083 [PTHR20854] INOSITOL MONOPHOSPHATASE; [GO:0046854] phosphatidylinositol phosphorylation; [PF00459] Inositol monophosphatase family; [PTHR20854:SF4] MYO INOSITOL MONOPHOSPHATASE; [KOG2951] Inositol monophosphatase 201.26 0.5779 190 Mapoly0013s0185 [PF03109] ABC1 family; [PTHR10566] CHAPERONE-ACTIVITY OF BC1 COMPLEX (CABC1)-RELATED; [KOG1235] Predicted unusual protein kinase; [PF01636] Phosphotransferase enzyme family 201.40 0.4738 191 Mapoly0043s0120 [K01527] nascent polypeptide-associated complex subunit beta; [PTHR10351] TRANSCRIPTION FACTOR BTF3; [KOG2240] RNA polymerase II general transcription factor BTF3 and related proteins; [PF01849] NAC domain 201.74 0.6891 192 Mapoly0005s0217 [KOG3428] Small nuclear ribonucleoprotein SMD1 and related snRNPs; [K11087] small nuclear ribonucleoprotein D1; [PTHR23338] SMALL NUCLEAR RIBONUCLEOPROTEIN SM; [PF01423] LSM domain 201.98 0.6799 193 Mapoly0003s0236 [PTHR11746] O-METHYLTRANSFERASE; [GO:0005737] cytoplasm; [PF02545] Maf-like protein; [KOG1509] Predicted nucleic acid-binding protein ASMTL; [K06287] septum formation protein 202.22 0.6884 194 Mapoly0066s0049 [PTHR12056] DNA-DIRECTED RNA POLYMERASES I, II, AND III; [GO:0003677] DNA binding; [KOG3507] DNA-directed RNA polymerase, subunit RPB7.0; [K03009] DNA-directed RNA polymerases I, II, and III subunit RPABC4; [GO:0006351] transcription, DNA-dependent; [GO:0003899] DNA-directed RNA polymerase activity; [PF03604] DNA directed RNA polymerase, 7 kDa subunit 203.75 0.6830 195 Mapoly0056s0016 [PTHR11359] AMP DEAMINASE; [PF00962] Adenosine/AMP deaminase; [GO:0032264] IMP salvage; [K01490] AMP deaminase [EC:3.5.4.6]; [GO:0019239] deaminase activity; [GO:0003876] AMP deaminase activity; [3.5.4.6] AMP deaminase.; [KOG1096] Adenosine monophosphate deaminase 205.49 0.6460 196 Mapoly0129s0047 [K10862] tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]; [KOG2031] Tyrosyl-DNA phosphodiesterase; [PTHR12415:SF0] SUBFAMILY NOT NAMED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF06087] Tyrosyl-DNA phosphodiesterase; [GO:0008081] phosphoric diester hydrolase activity; [PTHR12415] TYROSYL-DNA PHOSPHODIESTERASE 1; [3.1.4.-] Phosphoric diester hydrolases. 207.12 0.5645 197 Mapoly0047s0069 [GO:0005524] ATP binding; [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family; [KOG0358] Chaperonin complex component, TCP-1 delta subunit (CCT4) 207.13 0.6566 198 Mapoly0028s0141 [GO:0003723] RNA binding; [KOG2523] Predicted RNA-binding protein with PUA domain; [PF01472] PUA domain; [PTHR22798] MCT-1 PROTEIN; [K07575] PUA domain protein 207.29 0.6924 199 Mapoly0006s0058 [K06950] uncharacterized protein; [PF01966] HD domain 209.77 0.6385 200 Mapoly0097s0033 [PTHR10870] CELL CYCLE CHECKPOINT PROTEIN RAD1; [KOG3194] Checkpoint 9-1-1 complex, RAD1 component; [PF02144] Repair protein Rad1/Rec1/Rad17; [GO:0005634] nucleus; [K02830] cell cycle checkpoint protein [EC:3.1.11.2]; [GO:0006281] DNA repair; [3.1.11.2] Exodeoxyribonuclease III. 209.91 0.6227