Guide Gene
- Gene ID
- Mapoly0004s0213
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [PF03215] Rad17 cell cycle checkpoint protein; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PTHR12172] CELL CYCLE CHECKPOINT PROTEIN RAD17; [KOG1970] Checkpoint RAD17-RFC complex, RAD17/RAD24 component; [PTHR12172:SF0] SUBFAMILY NOT NAMED; [K06662] cell cycle checkpoint protein; [GO:0007049] cell cycle
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0004s0213 [PF03215] Rad17 cell cycle checkpoint protein; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PTHR12172] CELL CYCLE CHECKPOINT PROTEIN RAD17; [KOG1970] Checkpoint RAD17-RFC complex, RAD17/RAD24 component; [PTHR12172:SF0] SUBFAMILY NOT NAMED; [K06662] cell cycle checkpoint protein; [GO:0007049] cell cycle 0.00 1.0000 1 Mapoly0043s0062 [GO:0003677] DNA binding; [GO:0006284] base-excision repair; [PTHR10359] A/G-SPECIFIC ADENINE GLYCOSYLASE/ENDONUCLEASE III; [PF14815] NUDIX domain; [K03575] A/G-specific adenine glycosylase [EC:3.2.2.-]; [KOG1921] Endonuclease III; [PF00730] HhH-GPD superfamily base excision DNA repair protein; [PF00633] Helix-hairpin-helix motif; [3.2.2.-] Hydrolyzing N-glycosyl compounds. 1.00 0.8548 2 Mapoly0161s0023 [PTHR16119] FAMILY NOT NAMED; [PF07857] CEO family (DUF1632) 6.78 0.7422 3 Mapoly0015s0164 [GO:0003677] DNA binding; [PF02362] B3 DNA binding domain; [PTHR31391] FAMILY NOT NAMED 7.48 0.8088 4 Mapoly0100s0038 [GO:0007264] small GTPase mediated signal transduction; [PTHR24073] FAMILY NOT NAMED; [KOG0098] GTPase Rab2, small G protein superfamily; [PF15305] Intraflagellar transport protein 43; [PF00071] Ras family; [GO:0005525] GTP binding; [GO:0030991] intraflagellar transport particle A 8.06 0.7952 5 Mapoly0035s0108 [GO:0005524] ATP binding; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23074] AAA ATPASE; [KOG0740] AAA+-type ATPase; [PF09336] Vps4 C terminal oligomerisation domain; [PTHR23074:SF17] FIDGETIN LIKE-1 8.37 0.8035 6 Mapoly0005s0205 [PF00226] DnaJ domain; [KOG0719] Molecular chaperone (DnaJ superfamily); [PTHR24078] DNAJ HOMOLOG SUBFAMILY C MEMBER 8.49 0.8256 7 Mapoly0091s0017 [GO:0005515] protein binding; [PTHR22937] RING FINGER CONTAINING PROTEIN; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [KOG2177] Predicted E3 ubiquitin ligase; [K11985] TRAF-interacting protein 8.49 0.7953 8 Mapoly0135s0035 [GO:0003676] nucleic acid binding; [PF02037] SAP domain 9.00 0.8151 9 Mapoly0006s0078 [GO:0005515] protein binding; [PTHR10253] POLYCOMB PROTEIN; [KOG1034] Transcriptional repressor EED/ESC/FIE, required for transcriptional silencing, WD repeat superfamily; [K11462] polycomb protein EED; [PF00400] WD domain, G-beta repeat 9.49 0.8033 10 Mapoly0011s0137 [K03504] DNA polymerase delta subunit 3; [GO:0006260] DNA replication; [PTHR17598] FAMILY NOT NAMED; [PF09507] DNA polymerase subunit Cdc27; [GO:0005634] nucleus 12.04 0.8057 11 Mapoly0004s0008 - 12.96 0.7817 12 Mapoly0011s0143 [PTHR15481:SF0] SUBFAMILY NOT NAMED; [K14325] RNA-binding protein with serine-rich domain 1; [PTHR15481] RIBONUCLEIC ACID BINDING PROTEIN S1; [GO:0003676] nucleic acid binding; [KOG0130] RNA-binding protein RBM8/Tsunagi (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 14.90 0.8055 13 Mapoly0144s0027 [PTHR12872] ALPHA-N-ACETYLGLUCOSAMINIDASE; [KOG2233] Alpha-N-acetylglucosaminidase; [PF05089] Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain; [K01205] alpha-N-acetylglucosaminidase [EC:3.2.1.50]; [3.2.1.50] Alpha-N-acetylglucosaminidase.; [PF12972] Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain; [PF12971] Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain 16.43 0.7895 14 Mapoly0036s0012 [GO:0003723] RNA binding; [KOG3013] Exosomal 3'-5' exoribonuclease complex, subunit Rrp4; [PTHR21321] PNAS-3 RELATED; [PTHR21321:SF1] PNAS-3 RELATED; [K03679] exosome complex component RRP4; [GO:0000178] exosome (RNase complex) 17.75 0.7002 15 Mapoly0011s0139 - 19.36 0.6876 16 Mapoly0167s0006 - 20.45 0.7877 17 Mapoly0109s0054 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PF02229] Transcriptional Coactivator p15 (PC4); [KOG2712] Transcriptional coactivator; [PTHR13215] RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; [GO:0003713] transcription coactivator activity 20.49 0.7982 18 Mapoly0091s0013 [GO:0003723] RNA binding; [KOG2202] U2 snRNP splicing factor, small subunit, and related proteins; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PTHR12620] U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT; [GO:0005634] nucleus; [K12836] splicing factor U2AF 35 kDa subunit; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [GO:0046872] metal ion binding 20.59 0.8034 19 Mapoly0023s0050 [PF11559] Afadin- and alpha -actinin-Binding; [PTHR21736] VERNALIZATION-INSENSITIVE PROTEIN 3 24.00 0.7893 20 Mapoly0014s0097 [PF13414] TPR repeat; [KOG1308] Hsp70-interacting protein Hip/Transient component of progesterone receptor complexes and an Hsp70-binding protein; [PTHR22904:SF34] HSC70-INTERACTING PROTEIN; [PTHR22904] TPR REPEAT CONTAINING PROTEIN 27.04 0.7888 21 Mapoly0024s0100 [GO:0005524] ATP binding; [PTHR11669] REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; [KOG0990] Replication factor C, subunit RFC5; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08542] Replication factor C C-terminal domain; [K10756] replication factor C subunit 3/5 28.14 0.7957 22 Mapoly0039s0001 - 28.46 0.7611 23 Mapoly0021s0043 - 29.33 0.7819 24 Mapoly0087s0021 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [KOG0969] DNA polymerase delta, catalytic subunit; [PTHR10322:SF11] DNA POLYMERASE DELTA CATALYTIC SUBUNIT; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [K02327] DNA polymerase delta subunit 1 [EC:2.7.7.7]; [PF14260] C4-type zinc-finger of DNA polymerase delta; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT 30.59 0.7705 25 Mapoly0074s0069 - 31.18 0.7329 26 Mapoly0009s0136 [PTHR24012] FAMILY NOT NAMED; [KOG0126] Predicted RNA-binding protein (RRM superfamily); [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 31.43 0.7632 27 Mapoly0004s0058 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PTHR13215:SF4] SUBFAMILY NOT NAMED; [PF08766] DEK C terminal domain; [PF02229] Transcriptional Coactivator p15 (PC4); [KOG2712] Transcriptional coactivator; [PTHR13215] RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; [GO:0003713] transcription coactivator activity 32.12 0.7443 28 Mapoly0036s0142 [GO:0003677] DNA binding; [KOG1757] Histone 2A; [K11251] histone H2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 33.14 0.7883 29 Mapoly0033s0073 [PTHR10984:SF2] THIOREDOXIN-RELATED; [GO:0045454] cell redox homeostasis; [PTHR10984] ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN; [PF13850] Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC); [KOG2667] COPII vesicle protein; [PF00085] Thioredoxin; [PF07970] Endoplasmic reticulum vesicle transporter 33.17 0.7427 30 Mapoly0013s0048 [KOG0381] HMG box-containing protein; [PF00505] HMG (high mobility group) box; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN 33.88 0.7939 31 Mapoly0116s0028 [PTHR23074:SF19] KATANIN-RELATED; [GO:0005524] ATP binding; [3.6.4.3] Microtubule-severing ATPase.; [K07767] microtubule-severing ATPase [EC:3.6.4.3]; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0738] AAA+-type ATPase; [PTHR23074] AAA ATPASE; [PF09336] Vps4 C terminal oligomerisation domain 34.94 0.7477 32 Mapoly0159s0020 [K05544] tRNA-dihydrouridine synthase 3 [EC:1.-.-.-]; [GO:0050660] flavin adenine dinucleotide binding; [GO:0055114] oxidation-reduction process; [PTHR11082:SF8] TRNA-DIHYDROURIDINE SYNTHASE 3; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PF01207] Dihydrouridine synthase (Dus); [KOG2333] Uncharacterized conserved protein; [GO:0008033] tRNA processing; [PTHR11082] TRNA-DIHYDROURIDINE SYNTHASE; [GO:0046872] metal ion binding; [GO:0017150] tRNA dihydrouridine synthase activity; [1.-.-.-] Oxidoreductases. 35.72 0.7573 33 Mapoly0069s0082 [PTHR23002] ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding 36.52 0.7719 34 Mapoly0010s0062 [KOG2250] Glutamate/leucine/phenylalanine/valine dehydrogenases; [GO:0055114] oxidation-reduction process; [PTHR11606] GLUTAMATE DEHYDROGENASE; [GO:0016491] oxidoreductase activity; [PF00208] Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; [K00262] glutamate dehydrogenase (NADP+) [EC:1.4.1.4]; [GO:0006520] cellular amino acid metabolic process; [PTHR11606:SF4] SUBFAMILY NOT NAMED; [1.4.1.4] Glutamate dehydrogenase (NADP(+)).; [PF02812] Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 38.11 0.7757 35 Mapoly0103s0053 [GO:0008168] methyltransferase activity; [PTHR23068:SF3] gb def: Hypothetical protein T15N1_120; [PTHR23068] DNA (CYTOSINE-5-)-METHYLTRANSFERASE 3-RELATED; [PF00145] C-5 cytosine-specific DNA methylase 38.67 0.7263 36 Mapoly0001s0457 [PTHR14360:SF1] UNCHARACTERIZED; [PF07798] Protein of unknown function (DUF1640); [KOG3156] Uncharacterized membrane protein; [PTHR14360] UNCHARACTERIZED 40.30 0.7299 37 Mapoly0005s0130 [GO:0042393] histone binding; [PF02182] SAD/SRA domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF13923] Zinc finger, C3HC4 type (RING finger); [PTHR14140] E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED 40.53 0.7550 38 Mapoly0111s0035 [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PTHR12547] CCCH ZINC FINGER/TIS11-RELATED; [GO:0046872] metal ion binding; [KOG1677] CCCH-type Zn-finger protein 41.95 0.7463 39 Mapoly0073s0077 [PF07719] Tetratricopeptide repeat; [KOG1174] Anaphase-promoting complex (APC), subunit 7; [GO:0005515] protein binding; [PF13181] Tetratricopeptide repeat; [PTHR12558:SF8] ANAPHASE PROMOTING COMPLEX SUBUNIT 7; [PTHR12558] CELL DIVISION CYCLE 16,23,27 44.60 0.6781 40 Mapoly0024s0072 [KOG0005] Ubiquitin-like protein; [GO:0005515] protein binding; [PF00240] Ubiquitin family; [PTHR10666] UBIQUITIN; [K08770] ubiquitin C 45.46 0.7472 41 Mapoly0016s0080 [K14399] polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]; [PF03205] Molybdopterin guanine dinucleotide synthesis protein B; [KOG2749] mRNA cleavage and polyadenylation factor IA/II complex, subunit CLP1; [2.7.1.78] Polynucleotide 5'-hydroxyl-kinase.; [PTHR12755] CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P; [PF06807] Pre-mRNA cleavage complex II protein Clp1 46.86 0.7497 42 Mapoly0001s0022 [GO:0016020] membrane; [GO:0055085] transmembrane transport; [PTHR30566] YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; [PF00924] Mechanosensitive ion channel 47.75 0.7296 43 Mapoly0005s0256 [PF12220] U1 small nuclear ribonucleoprotein of 70kDa MW N terminal; [KOG0113] U1 small nuclear ribonucleoprotein (RRM superfamily); [PTHR13952:SF5] PREDICTED: HYPOTHETICAL PROTEIN, PARTIAL; [PTHR13952] U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD; [K11093] U1 small nuclear ribonucleoprotein 70kDa; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 48.54 0.7476 44 Mapoly0043s0127 [GO:0031625] ubiquitin protein ligase binding; [GO:0031461] cullin-RING ubiquitin ligase complex; [GO:0006511] ubiquitin-dependent protein catabolic process; [K10609] cullin 4; [PF10557] Cullin protein neddylation domain; [PTHR11932] CULLIN; [PF00888] Cullin family; [KOG2167] Cullins; [PTHR11932:SF27] SUBFAMILY NOT NAMED 49.99 0.7367 45 Mapoly0036s0154 [KOG2606] OTU (ovarian tumor)-like cysteine protease; [PTHR12419] OTU DOMAIN CONTAINING PROTEIN; [PTHR12419:SF10] gb def: ENSANGP00000019868 (Fragment); [PF02338] OTU-like cysteine protease 52.25 0.7564 46 Mapoly0014s0155 [PF08321] PPP5 TPR repeat region; [GO:0005737] cytoplasm; [PTHR11668] SERINE/THREONINE PROTEIN PHOSPHATASE; [PF00149] Calcineurin-like phosphoesterase; [GO:0005515] protein binding; [GO:0016787] hydrolase activity; [PF13414] TPR repeat; [GO:0004721] phosphoprotein phosphatase activity; [GO:0006470] protein dephosphorylation; [GO:0005634] nucleus; [PTHR11668:SF12] PROTEIN PHOSPHATASE-5; [PF00515] Tetratricopeptide repeat; [KOG0376] Serine-threonine phosphatase 2A, catalytic subunit; [3.1.3.16] Phosphoprotein phosphatase.; [K04460] protein phosphatase 5 [EC:3.1.3.16] 52.92 0.7311 47 Mapoly0005s0267 [PTHR23111] ZINC FINGER PROTEIN; [GO:0008270] zinc ion binding; [PF00641] Zn-finger in Ran binding protein and others 53.37 0.7550 48 Mapoly0002s0230 [GO:0003677] DNA binding; [GO:0000784] nuclear chromosome, telomeric region; [PF02765] Telomeric single stranded DNA binding POT1/CDC13; [GO:0043047] single-stranded telomeric DNA binding; [PTHR14513] PROTECTION OF TELOMERES 1; [KOG4757] Predicted telomere binding protein; [GO:0000723] telomere maintenance 54.19 0.7078 49 Mapoly0001s0266 [GO:0003677] DNA binding; [PF01192] RNA polymerase Rpb6; [KOG3405] RNA polymerase subunit K; [PTHR10773] DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2; [GO:0006351] transcription, DNA-dependent; [GO:0003899] DNA-directed RNA polymerase activity; [K03014] DNA-directed RNA polymerases I, II, and III subunit RPABC2 55.81 0.7498 50 Mapoly0002s0217 [PF00183] Hsp90 protein; [GO:0005524] ATP binding; [GO:0006950] response to stress; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [GO:0006457] protein folding; [K04079] molecular chaperone HtpG; [PTHR11528] HEAT SHOCK PROTEIN 90; [KOG0019] Molecular chaperone (HSP90 family); [GO:0051082] unfolded protein binding 57.46 0.6867 51 Mapoly0033s0129 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0003910] DNA ligase (ATP) activity; [PF04679] ATP dependent DNA ligase C terminal region; [PTHR10459] DNA LIGASE; [K10747] DNA ligase 1 [EC:6.5.1.1]; [PF01068] ATP dependent DNA ligase domain; [6.5.1.1] DNA ligase (ATP).; [GO:0006281] DNA repair; [PF04675] DNA ligase N terminus; [PTHR10459:SF10] DNA LIGASE I; [GO:0006310] DNA recombination; [KOG0967] ATP-dependent DNA ligase I 58.33 0.7275 52 Mapoly0087s0074 [GO:0005685] U1 snRNP; [PF06220] U1 zinc finger; [GO:0008270] zinc ion binding; [GO:0000398] mRNA splicing, via spliceosome; [KOG3454] U1 snRNP-specific protein C; [GO:0000387] spliceosomal snRNP assembly; [PTHR31148] FAMILY NOT NAMED 58.60 0.7501 53 Mapoly0191s0002 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [K07374] tubulin alpha; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [KOG1376] Alpha tubulin; [GO:0005525] GTP binding 63.87 0.7374 54 Mapoly0057s0080 [PTHR15140:SF6] SUBFAMILY NOT NAMED; [KOG3207] Beta-tubulin folding cofactor E; [PF01302] CAP-Gly domain; [PTHR15140] TUBULIN-SPECIFIC CHAPERONE E 64.97 0.7244 55 Mapoly0027s0010 [K12580] CCR4-NOT transcription complex subunit 3; [PTHR23326:SF1] CCR4 NOT-RELATED; [GO:0006355] regulation of transcription, DNA-dependent; [PF04153] NOT2 / NOT3 / NOT5 family; [GO:0005634] nucleus; [PTHR23326] CCR4 NOT-RELATED; [PF04065] Not1 N-terminal domain, CCR4-Not complex component 65.42 0.6981 56 Mapoly0132s0046 [PF00855] PWWP domain; [PTHR12550] HEPATOMA-DERIVED GROWTH FACTOR-RELATED; [PTHR12550:SF5] UNCHARACTERIZED 65.50 0.7257 57 Mapoly0014s0033 [KOG4285] Mitotic phosphoprotein; [PTHR21527] FAMILY NOT NAMED; [K14313] nuclear pore complex protein Nup53; [PF05172] Nup53/35/40-type RNA recognition motif 65.51 0.7178 58 Mapoly0083s0062 [K09553] stress-induced-phosphoprotein 1; [GO:0005515] protein binding; [PF13414] TPR repeat; [KOG0548] Molecular co-chaperone STI1; [PF00515] Tetratricopeptide repeat; [PTHR22904] TPR REPEAT CONTAINING PROTEIN 65.57 0.7032 59 Mapoly0059s0079 [KOG2014] SMT3/SUMO-activating complex, AOS1/RAD31 component; [PF00899] ThiF family; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [K10684] ubiquitin-like 1-activating enzyme E1 A [EC:6.3.2.19] 65.75 0.7513 60 Mapoly0001s0064 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [GO:0008173] RNA methyltransferase activity; [PTHR12029] RNA METHYLTRANSFERASE; [KOG0838] RNA Methylase, SpoU family; [PF00588] SpoU rRNA Methylase family 67.04 0.7445 61 Mapoly0044s0136 [PF12171] Zinc-finger double-stranded RNA-binding; [K13104] zinc finger protein 830; [PTHR13278] UNCHARACTERIZED; [KOG3032] Uncharacterized conserved protein 68.26 0.6466 62 Mapoly0042s0032 [PF13259] Protein of unknown function (DUF4050) 68.67 0.7460 63 Mapoly0002s0042 [GO:0031011] Ino80 complex; [PTHR13052:SF0] SUBFAMILY NOT NAMED; [PTHR13052] NFRKB-RELATED 68.93 0.7198 64 Mapoly0086s0078 [GO:0003677] DNA binding; [GO:0006275] regulation of DNA replication; [GO:0030337] DNA polymerase processivity factor activity; [PTHR11352] PROLIFERATING CELL NUCLEAR ANTIGEN; [PF00705] Proliferating cell nuclear antigen, N-terminal domain; [KOG1636] DNA polymerase delta processivity factor (proliferating cell nuclear antigen); [PF02747] Proliferating cell nuclear antigen, C-terminal domain 69.17 0.7335 65 Mapoly0070s0095 [PTHR23215] ZINC FINGER PROTEIN 207; [KOG2893] Zn finger protein 69.83 0.7334 66 Mapoly0014s0191 [GO:0006355] regulation of transcription, DNA-dependent; [PTHR15970] FAMILY NOT NAMED; [GO:0032783] ELL-EAF complex; [KOG4795] Protein associated with transcriptional elongation factor ELL; [PTHR15970:SF2] GB DEF: HYPOTHETICAL PROTEIN F23N20.7 (AT1G71080/F23N20_7); [PF09816] RNA polymerase II transcription elongation factor 73.03 0.6091 67 Mapoly0057s0091 [PF04577] Protein of unknown function (DUF563); [PTHR20961] GLYCOSYLTRANSFERASE; [GO:0016757] transferase activity, transferring glycosyl groups 73.10 0.6196 68 Mapoly0084s0084 [PF01221] Dynein light chain type 1; [GO:0005875] microtubule associated complex; [GO:0007017] microtubule-based process; [KOG3430] Dynein light chain type 1; [PTHR11886] DYNEIN LIGHT CHAIN; [K10418] dynein light chain LC8-type 73.76 0.7108 69 Mapoly0028s0075 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [K11251] histone H2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 75.00 0.7653 70 Mapoly0049s0118 [PTHR32002] FAMILY NOT NAMED; [PF02042] RWP-RK domain 75.11 0.7074 71 Mapoly0107s0039 [PF03819] MazG nucleotide pyrophosphohydrolase domain; [PTHR14552:SF2] SUBFAMILY NOT NAMED; [PTHR14552] FAMILY NOT NAMED; [PF13837] Myb/SANT-like DNA-binding domain 76.23 0.6793 72 Mapoly0002s0191 [GO:0008168] methyltransferase activity; [PTHR10108] METHYLTRANSFERASE; [PF08241] Methyltransferase domain; [GO:0008152] metabolic process; [KOG4300] Predicted methyltransferase 76.54 0.6529 73 Mapoly0081s0019 [PF00083] Sugar (and other) transporter; [GO:0016021] integral to membrane; [GO:0055085] transmembrane transport; [KOG0255] Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily); [PTHR24064] FAMILY NOT NAMED; [GO:0022857] transmembrane transporter activity 77.36 0.6237 74 Mapoly0013s0062 [GO:0003677] DNA binding; [PTHR15348:SF0] SUBFAMILY NOT NAMED; [PF01388] ARID/BRIGHT DNA binding domain; [GO:0005622] intracellular; [PTHR15348] AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN (ARID DOMAIN- CONTAINING PROTEIN) (DEAD RINGER PROTEIN) (B-CELL REGULATOR OF IGH TRANSCRIPTION) (BRIGHT) 77.58 0.7350 75 Mapoly0177s0009 [KOG2641] Predicted seven transmembrane receptor - rhodopsin family; [PTHR23423] ORGANIC SOLUTE TRANSPORTER-RELATED; [PF03619] Organic solute transporter Ostalpha 77.77 0.6096 76 Mapoly0001s0197 [K10733] GINS complex subunit 2; [GO:0006260] DNA replication; [PF05916] GINS complex protein; [GO:0005634] nucleus; [KOG4071] Uncharacterized conserved protein; [PTHR12772] DNA REPLICATION COMPLEX GINS PROTEIN PSF2 79.51 0.6954 77 Mapoly0006s0255 [GO:0003723] RNA binding; [PTHR10288] KH DOMAIN CONTAINING RNA BINDING PROTEIN; [PF00013] KH domain; [KOG2192] PolyC-binding hnRNP-K protein HRB57A/hnRNP, contains KH domain; [K13210] far upstream element-binding protein 80.00 0.7361 78 Mapoly0104s0042 [PTHR22846:SF2] TRANSDUCIN BETA-LIKE 1; [GO:0005515] protein binding; [PTHR22846] WD40 REPEAT PROTEIN; [KOG0273] Beta-transducin family (WD-40 repeat) protein; [PF08513] LisH; [PF00400] WD domain, G-beta repeat 82.70 0.7304 79 Mapoly0167s0026 [PTHR19134] PROTEIN-TYROSINE PHOSPHATASE; [PF00102] Protein-tyrosine phosphatase; [GO:0006470] protein dephosphorylation; [KOG0789] Protein tyrosine phosphatase; [GO:0004725] protein tyrosine phosphatase activity 85.42 0.6642 80 Mapoly0051s0078 [GO:0006355] regulation of transcription, DNA-dependent; [KOG0266] WD40 repeat-containing protein; [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [PF00400] WD domain, G-beta repeat 86.08 0.7127 81 Mapoly0084s0054 [K03029] 26S proteasome regulatory subunit N10; [PF02809] Ubiquitin interaction motif; [PF13519] von Willebrand factor type A domain; [GO:0006511] ubiquitin-dependent protein catabolic process; [PTHR10223] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4; [GO:0008540] proteasome regulatory particle, base subcomplex; [KOG2884] 26S proteasome regulatory complex, subunit RPN10/PSMD4 86.90 0.7264 82 Mapoly0115s0039 [KOG1780] Small Nuclear ribonucleoprotein G; [K11099] small nuclear ribonucleoprotein G; [PF01423] LSM domain; [PTHR10553] SMALL NUCLEAR RIBONUCLEOPROTEIN 88.39 0.7594 83 Mapoly0001s0238 [PF02978] Signal peptide binding domain; [GO:0048500] signal recognition particle; [PF00448] SRP54-type protein, GTPase domain; [GO:0008312] 7S RNA binding; [K03106] signal recognition particle subunit SRP54; [KOG0780] Signal recognition particle, subunit Srp54; [GO:0006614] SRP-dependent cotranslational protein targeting to membrane; [PF02881] SRP54-type protein, helical bundle domain; [GO:0005525] GTP binding; [PTHR11564:SF5] SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN; [PTHR11564] GTPASE CONTAINING FAMILY OF SIGNAL RECOGNITION PARTICLE PROTEINS 88.99 0.6752 84 Mapoly0101s0048 [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat 89.12 0.7413 85 Mapoly0146s0045 [GO:0003723] RNA binding; [PTHR11207:SF1] RIBONUCLEASE III; [PF00035] Double-stranded RNA binding motif; [GO:0004525] ribonuclease III activity; [GO:0016075] rRNA catabolic process; [PTHR11207] RIBONUCLEASE III 89.92 0.7326 86 Mapoly0028s0110 [GO:0005524] ATP binding; [PTHR23069] TAT-BINDING HOMOLOG 7; [PTHR23069:SF0] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [PF00439] Bromodomain; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0732] AAA+-type ATPase containing the bromodomain 90.56 0.7298 87 Mapoly0002s0237 [PTHR12864] RAN BINDING PROTEIN 9-RELATED; [PF10607] CTLH/CRA C-terminal to LisH motif domain; [GO:0005515] protein binding; [KOG1477] SPRY domain-containing proteins; [PTHR12864:SF1] RAN BINDING PROTEIN 9-RELATED; [PF00622] SPRY domain 92.79 0.6570 88 Mapoly0019s0083 [PTHR20854] INOSITOL MONOPHOSPHATASE; [GO:0046854] phosphatidylinositol phosphorylation; [PF00459] Inositol monophosphatase family; [PTHR20854:SF4] MYO INOSITOL MONOPHOSPHATASE; [KOG2951] Inositol monophosphatase 93.33 0.6309 89 Mapoly0101s0017 [KOG1294] Apurinic/apyrimidinic endonuclease and related enzymes; [PTHR22748:SF1] AP ENDONUCLEASE; [GO:0006281] DNA repair; [PF03372] Endonuclease/Exonuclease/phosphatase family; [GO:0004518] nuclease activity; [PTHR22748] AP ENDONUCLEASE 94.95 0.7073 90 Mapoly0078s0038 [GO:0031072] heat shock protein binding; [KOG0712] Molecular chaperone (DnaJ superfamily); [PTHR24076:SF1] SUBFAMILY NOT NAMED; [PF00226] DnaJ domain; [PF01556] DnaJ C terminal domain; [PTHR24076] FAMILY NOT NAMED; [PF00684] DnaJ central domain; [GO:0051082] unfolded protein binding 95.25 0.6735 91 Mapoly0001s0009 [PTHR10540:SF7] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7; [GO:0005515] protein binding; [PF13012] Maintenance of mitochondrial structure and function; [PTHR10540] EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED; [PF01398] JAB1/Mov34/MPN/PAD-1 ubiquitin protease; [KOG1556] 26S proteasome regulatory complex, subunit RPN8/PSMD7; [K03038] 26S proteasome regulatory subunit N8 96.05 0.7422 92 Mapoly0151s0042 [PTHR31500:SF0] SUBFAMILY NOT NAMED; [PF03479] Domain of unknown function (DUF296); [PTHR31500] FAMILY NOT NAMED 96.28 0.7013 93 Mapoly0060s0056 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 97.58 0.7237 94 Mapoly0030s0061 [GO:0005663] DNA replication factor C complex; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [GO:0003689] DNA clamp loader activity; [PF00533] BRCA1 C Terminus (BRCT) domain; [K10754] replication factor C subunit 1; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08519] Replication factor RFC1 C terminal domain; [KOG1968] Replication factor C, subunit RFC1 (large subunit) 97.98 0.7120 95 Mapoly0001s0348 [KOG1342] Histone deacetylase complex, catalytic component RPD3; [PF00850] Histone deacetylase domain; [PTHR10625] HISTONE DEACETYLASE 100.69 0.6829 96 Mapoly0058s0108 [GO:0003677] DNA binding; [KOG0214] RNA polymerase II, second largest subunit; [PF04567] RNA polymerase Rpb2, domain 5; [PF04565] RNA polymerase Rpb2, domain 3; [PTHR20856] DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2; [PF00562] RNA polymerase Rpb2, domain 6; [PF04566] RNA polymerase Rpb2, domain 4; [GO:0032549] ribonucleoside binding; [PF04561] RNA polymerase Rpb2, domain 2; [GO:0006351] transcription, DNA-dependent; [GO:0003899] DNA-directed RNA polymerase activity; [PF04560] RNA polymerase Rpb2, domain 7; [PF04563] RNA polymerase beta subunit 101.44 0.7033 97 Mapoly0041s0007 [GO:0016272] prefoldin complex; [PF02996] Prefoldin subunit; [KOG3048] Molecular chaperone Prefoldin, subunit 5; [GO:0006457] protein folding; [PTHR12674] PREFOLDIN SUBUNIT 5; [GO:0051082] unfolded protein binding; [K04797] prefoldin alpha subunit 103.61 0.7286 98 Mapoly0185s0017 [GO:0030915] Smc5-Smc6 complex; [PF08746] RING-like domain; [KOG4718] Non-SMC (structural maintenance of chromosomes) element 1 protein (NSE1); [PTHR20973] NON-SMC ELEMENT 1-RELATED; [PF07574] Nse1 non-SMC component of SMC5-6 complex; [GO:0006281] DNA repair; [PTHR20973:SF0] SUBFAMILY NOT NAMED 104.63 0.7240 99 Mapoly0059s0005 [GO:0016020] membrane; [PF00072] Response regulator receiver domain; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [GO:0000160] phosphorelay signal transduction system; [KOG0519] Sensory transduction histidine kinase; [GO:0007165] signal transduction; [PTHR24423] TWO-COMPONENT SENSOR HISTIDINE KINASE; [PF05231] MASE1; [PF00512] His Kinase A (phospho-acceptor) domain; [GO:0000155] phosphorelay sensor kinase activity 104.93 0.6805 100 Mapoly0043s0082 [PF07899] Frigida-like protein; [PTHR31791] FAMILY NOT NAMED 104.96 0.7013 101 Mapoly0052s0111 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG4206] Spliceosomal protein snRNP-U1A/U2B; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED 105.21 0.7078 102 Mapoly0152s0004 [PTHR12460] CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN; [PTHR12460:SF4] SUBFAMILY NOT NAMED; [PF04818] RNA polymerase II-binding domain.; [KOG2669] Regulator of nuclear mRNA 107.14 0.7114 103 Mapoly0011s0134 - 107.74 0.7193 104 Mapoly0056s0016 [PTHR11359] AMP DEAMINASE; [PF00962] Adenosine/AMP deaminase; [GO:0032264] IMP salvage; [K01490] AMP deaminase [EC:3.5.4.6]; [GO:0019239] deaminase activity; [GO:0003876] AMP deaminase activity; [3.5.4.6] AMP deaminase.; [KOG1096] Adenosine monophosphate deaminase 107.96 0.6880 105 Mapoly0071s0007 [GO:0005524] ATP binding; [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family; [K09494] T-complex protein 1 subunit beta; [KOG0363] Chaperonin complex component, TCP-1 beta subunit (CCT2) 109.17 0.7097 106 Mapoly0218s0012 [PTHR15744:SF0] SUBFAMILY NOT NAMED; [PTHR15744] BLOM7 109.50 0.6952 107 Mapoly0001s0015 [PTHR13555] C2H2 ZINC FINGER CGI-62-RELATED 110.31 0.6774 108 Mapoly0081s0083 [GO:0005524] ATP binding; [PTHR24054] CASEIN KINASE II SUBUNIT ALPHA; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K03097] casein kinase II subunit alpha [EC:2.7.11.1]; [GO:0006468] protein phosphorylation; [KOG0668] Casein kinase II, alpha subunit 111.02 0.6802 109 Mapoly0103s0063 [PTHR21419] FAMILY NOT NAMED; [PF13517] Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 111.62 0.6135 110 Mapoly0023s0062 [K11086] small nuclear ribonucleoprotein B and B'; [PTHR10701] SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N; [KOG3168] U1 snRNP component; [PF01423] LSM domain 112.50 0.6940 111 Mapoly0029s0136 [PTHR21206:SF0] SUBFAMILY NOT NAMED; [PF05916] GINS complex protein; [KOG3176] Predicted alpha-helical protein, potentially involved in replication/repair; [PTHR21206] SLD5 PROTEIN; [K10735] GINS complex subunit 4 112.66 0.7158 112 Mapoly0108s0026 [GO:0016020] membrane; [GO:0006486] protein glycosylation; [KOG2292] Oligosaccharyltransferase, STT3 subunit; [2.4.1.119] Transferred entry: 2.4.99.18.; [PTHR13872] 60S RIBOSOMAL PROTEIN L35; [K07151] dolichyl-diphosphooligosaccharide--protein glycosyltransferase [EC:2.4.1.119]; [PF02516] Oligosaccharyl transferase STT3 subunit; [GO:0004576] oligosaccharyl transferase activity 113.48 0.6753 113 Mapoly0007s0143 [KOG2235] Uncharacterized conserved protein; [PTHR31057] FAMILY NOT NAMED; [PF09743] Uncharacterized conserved protein (DUF2042); [PTHR31057:SF0] SUBFAMILY NOT NAMED 114.11 0.6820 114 Mapoly0027s0185 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF39] CDC2-RELATED PROTEIN KINASE; [KOG0600] Cdc2-related protein kinase; [K08819] Cdc2-related kinase, arginine/serine-rich [EC:2.7.11.22]; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 114.26 0.7065 115 Mapoly0115s0071 [GO:0005515] protein binding; [PF13414] TPR repeat; [PF00226] DnaJ domain; [PF00515] Tetratricopeptide repeat; [PTHR24078] DNAJ HOMOLOG SUBFAMILY C MEMBER; [KOG0550] Molecular chaperone (DnaJ superfamily) 116.39 0.5667 116 Mapoly0066s0106 [PTHR15588] LSM1; [KOG1784] Small Nuclear ribonucleoprotein splicing factor; [K12627] U6 snRNA-associated Sm-like protein LSm8; [PF01423] LSM domain 116.47 0.6924 117 Mapoly0084s0045 [PF07719] Tetratricopeptide repeat; [KOG1211] Amidases; [PF13414] TPR repeat; [PTHR11895] AMIDASE; [GO:0016884] carbon-nitrogen ligase activity, with glutamine as amido-N-donor; [PTHR11895:SF6] AMIDASE; [PF01425] Amidase 117.54 0.6773 118 Mapoly0174s0020 [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PF13086] AAA domain; [PF13087] AAA domain; [KOG1801] tRNA-splicing endonuclease positive effector (SEN1) 117.58 0.7127 119 Mapoly0019s0051 [GO:0003723] RNA binding; [PTHR23270] PROGRAMMED CELL DEATH PROTEIN 11 (PRE-RRNA PROCESSING PROTEIN RRP5); [GO:0006397] mRNA processing; [GO:0005634] nucleus; [PF00575] S1 RNA binding domain; [KOG1070] rRNA processing protein Rrp5; [PF05843] Suppressor of forked protein (Suf) 118.07 0.6753 120 Mapoly0113s0037 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [KOG2577] Transcription factor E2F/dimerization partner (TDP); [PTHR12081] TRANSCRIPTION FACTOR E2F 118.60 0.7046 121 Mapoly0064s0055 [PF13656] RNA polymerase Rpb3/Rpb11 dimerisation domain; [K03008] DNA-directed RNA polymerase II subunit RPB11; [PTHR13946] DNA-DIRECTED RNA POLYMERASE I,II,III; [KOG4392] RNA polymerase, subunit L 121.47 0.7276 122 Mapoly0034s0111 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 122.11 0.7234 123 Mapoly0011s0083 [PTHR10997] IMPORTIN-7, 8, 11 125.02 0.7147 124 Mapoly0029s0049 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0016602] CCAAT-binding factor complex; [KOG1657] CCAAT-binding factor, subunit C (HAP5); [GO:0043565] sequence-specific DNA binding; [PF00808] Histone-like transcription factor (CBF/NF-Y) and archaeal histone; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PTHR10252:SF8] TRANSCRIPTIONAL ACTIVATOR HAP5; [GO:0005622] intracellular; [PTHR10252] HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED 125.58 0.7069 125 Mapoly0002s0249 [GO:0006289] nucleotide-excision repair; [GO:0005515] protein binding; [KOG0011] Nucleotide excision repair factor NEF2, RAD23 component; [PTHR10621] UV EXCISION REPAIR PROTEIN RAD23; [PF09280] XPC-binding domain; [PF00627] UBA/TS-N domain; [PF00240] Ubiquitin family; [GO:0003684] damaged DNA binding; [GO:0043161] proteasomal ubiquitin-dependent protein catabolic process; [K10839] UV excision repair protein RAD23 126.90 0.6845 126 Mapoly0021s0138 [KOG1548] Transcription elongation factor TAT-SF1; [GO:0005515] protein binding; [K13093] HIV Tat-specific factor 1; [PF02213] GYF domain; [PTHR15608] SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2; [PF14237] Domain of unknown function (DUF4339); [GO:0003676] nucleic acid binding; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 127.79 0.6923 127 Mapoly0125s0028 [GO:0000166] nucleotide binding; [PF00702] haloacid dehalogenase-like hydrolase; [KOG0205] Plasma membrane H+-transporting ATPase; [PTHR24093] FAMILY NOT NAMED; [PF00690] Cation transporter/ATPase, N-terminus; [GO:0046872] metal ion binding; [PF00122] E1-E2 ATPase 129.48 0.7025 128 Mapoly0005s0217 [KOG3428] Small nuclear ribonucleoprotein SMD1 and related snRNPs; [K11087] small nuclear ribonucleoprotein D1; [PTHR23338] SMALL NUCLEAR RIBONUCLEOPROTEIN SM; [PF01423] LSM domain 132.19 0.7160 129 Mapoly0057s0039 [PTHR12409] PREFOLDIN SUBUNIT 3; [GO:0016272] prefoldin complex; [PF02996] Prefoldin subunit; [KOG3313] Molecular chaperone Prefoldin, subunit 3; [GO:0006457] protein folding; [GO:0051082] unfolded protein binding 132.85 0.6769 130 Mapoly0001s0273 [PTHR10501] U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B; [PTHR10501:SF0] SMALL NUCLEAR RIBONUCLEOPROTEIN; [GO:0000398] mRNA splicing, via spliceosome; [GO:0003676] nucleic acid binding; [GO:0017069] snRNA binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 133.90 0.6972 131 Mapoly0090s0070 [PF00169] PH domain 134.77 0.6437 132 Mapoly0005s0021 [PF13266] Protein of unknown function (DUF4057); [PTHR31132] FAMILY NOT NAMED 134.82 0.7198 133 Mapoly0063s0041 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR23340] ARGININE/SERINE RICH SPLICING FACTOR SF4/14; [PF01585] G-patch domain; [GO:0003676] nucleic acid binding; [PF01805] Surp module 134.83 0.6896 134 Mapoly0106s0044 [PF03980] Nnf1 134.97 0.6563 135 Mapoly0120s0004 [PF00488] MutS domain V; [GO:0005524] ATP binding; [K08735] DNA mismatch repair protein MSH2; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PTHR11361:SF35] MUTS HOMOLOG 2, MSH2; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III; [KOG0219] Mismatch repair ATPase MSH2 (MutS family); [PF05190] MutS family domain IV 135.04 0.7071 136 Mapoly0002s0271 - 135.27 0.6728 137 Mapoly0062s0108 [GO:0005524] ATP binding; [2.7.11.26] [Tau protein] kinase.; [PF00069] Protein kinase domain; [KOG0658] Glycogen synthase kinase-3; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24057] GLYCOGEN SYNTHASE KINASE-3 ALPHA; [K03083] glycogen synthase kinase 3 beta [EC:2.7.11.26] 139.57 0.6853 138 Mapoly0013s0016 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR31614] FAMILY NOT NAMED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08661] Replication factor A protein 3; [GO:0006310] DNA recombination 140.57 0.7009 139 Mapoly0005s0067 [PTHR15242:SF0] SUBFAMILY NOT NAMED; [PTHR15242] SPLICING FACTOR, ARGININE/SERINE-RICH 2,RNAP C-TERM INTERACTING PROTEIN; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 141.07 0.7072 140 Mapoly0105s0015 [GO:0003677] DNA binding; [KOG2393] Transcription initiation factor IIF, large subunit (RAP74); [GO:0032968] positive regulation of transcription elongation from RNA polymerase II promoter; [K03138] transcription initiation factor TFIIF subunit alpha; [PF05793] Transcription initiation factor IIF, alpha subunit (TFIIF-alpha); [PTHR13011] TFIIF-ALPHA; [GO:0005634] nucleus; [GO:0006367] transcription initiation from RNA polymerase II promoter 141.43 0.6801 141 Mapoly0011s0077 [PTHR23419:SF0] SUBFAMILY NOT NAMED; [KOG3338] Divalent cation tolerance-related protein; [GO:0010038] response to metal ion; [PF03091] CutA1 divalent ion tolerance protein; [K03926] periplasmic divalent cation tolerance protein; [PTHR23419] DIVALENT CATION TOLERANCE CUTA-RELATED 142.60 0.7111 142 Mapoly0109s0009 [K03574] 7,8-dihydro-8-oxoguanine triphosphatase [EC:3.6.1.-]; [GO:0016787] hydrolase activity; [PTHR22769] MUTT/NUDIX HYDROLASE; [3.6.1.-] In phosphorous-containing anhydrides.; [PF00293] NUDIX domain 143.09 0.6638 143 Mapoly0101s0047 [KOG2084] Predicted histone tail methylase containing SET domain; [GO:0005515] protein binding; [PF00856] SET domain; [K11426] SET and MYND domain-containing protein; [PTHR12197] SET AND MYND DOMAIN CONTAINING; [PF01753] MYND finger 143.54 0.5623 144 Mapoly0007s0227 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02212] minichromosome maintenance protein 4 (cell division control protein 54); [KOG0478] DNA replication licensing factor, MCM4 component; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 144.56 0.7115 145 Mapoly0046s0055 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [KOG1374] Gamma tubulin; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [GO:0031122] cytoplasmic microtubule organization; [PTHR11588:SF7] TUBULIN GAMMA CHAIN; [K10389] tubulin gamma; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0007020] microtubule nucleation; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0000930] gamma-tubulin complex; [GO:0043234] protein complex; [GO:0005525] GTP binding 144.88 0.6826 146 Mapoly0014s0204 [PTHR24012] FAMILY NOT NAMED; [PTHR24012:SF31] SUBFAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 145.72 0.6775 147 Mapoly0105s0026 - 145.99 0.6803 148 Mapoly0042s0007 [GO:0003677] DNA binding; [K02213] cell division control protein 6; [KOG2227] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase; [PF13401] AAA domain; [PF01429] Methyl-CpG binding domain; [GO:0005634] nucleus; [PF09079] CDC6, C terminal; [PTHR10763] CELL DIVISION CONTROL PROTEIN 6-RELATED 146.74 0.6940 149 Mapoly0045s0075 - 147.43 0.6648 150 Mapoly0083s0001 [GO:0008168] methyltransferase activity; [PF05891] AdoMet dependent proline di-methyltransferase; [PTHR12753] AD-003 - RELATED 147.97 0.6663 151 Mapoly0005s0080 [GO:0006355] regulation of transcription, DNA-dependent; [KOG0794] CDK8 kinase-activating protein cyclin C; [GO:0019901] protein kinase binding; [PF00134] Cyclin, N-terminal domain; [PTHR10026] CYCLIN; [GO:0000079] regulation of cyclin-dependent protein serine/threonine kinase activity 148.14 0.6559 152 Mapoly0045s0049 - 150.13 0.6644 153 Mapoly0014s0064 [PTHR10552] U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A; [K11092] U2 small nuclear ribonucleoprotein A'; [KOG1644] U2-associated snRNP A' protein; [PF14580] Leucine-rich repeat 150.44 0.6887 154 Mapoly0007s0163 [PTHR22055] 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN (PDGF-ASSOCIATED PROTEIN); [PF10252] Casein kinase substrate phosphoprotein PP28; [KOG3375] Phosphoprotein/predicted coiled-coil protein 150.97 0.7082 155 Mapoly0029s0121 [K11550] kinetochore protein Spc25, animal type; [PF08234] Chromosome segregation protein Spc25; [PTHR14281] FAMILY NOT NAMED 152.53 0.7033 156 Mapoly0031s0122 [PF10151] Uncharacterised conserved protein (DUF2359); [PTHR13448] UNCHARACTERIZED; [KOG4467] Uncharacterized conserved protein 154.73 0.6875 157 Mapoly0027s0144 [GO:0016272] prefoldin complex; [KOG3501] Molecular chaperone Prefoldin, subunit 1; [PTHR20903] PREFOLDIN SUBUNIT 1-RELATED; [GO:0006457] protein folding; [GO:0051082] unfolded protein binding; [PF01920] Prefoldin subunit 155.25 0.6846 158 Mapoly0005s0052 [GO:0005515] protein binding; [KOG1463] 26S proteasome regulatory complex, subunit RPN6/PSMD11; [PF01399] PCI domain; [PTHR10678] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2; [PTHR10678:SF2] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11 (26S PROTEASOME REGULATORY SUBUNIT S9); [K03036] 26S proteasome regulatory subunit N6 158.62 0.6728 159 Mapoly0032s0081 [GO:0008641] small protein activating enzyme activity; [GO:0045116] protein neddylation; [GO:0005524] ATP binding; [PTHR10953:SF6] UBIQUITIN-ACTIVATING ENZYME E1C (NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT); [KOG2015] NEDD8-activating complex, catalytic component UBA3; [PF08825] E2 binding domain; [GO:0016881] acid-amino acid ligase activity; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [K10686] ubiquitin-activating enzyme E1 C [EC:6.3.2.19] 158.89 0.6650 160 Mapoly0071s0008 [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [KOG0107] Alternative splicing factor SRp20/9G8 (RRM superfamily); [GO:0003676] nucleic acid binding; [PTHR10548] SPLICING FACTOR, ARGININE/SERINE-RICH; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 160.22 0.6843 161 Mapoly0001s0011 [K02219] cyclin-dependent kinase regulatory subunit CKS1; [KOG3484] Cyclin-dependent protein kinase CDC28, regulatory subunit CKS1, and related proteins; [PF01111] Cyclin-dependent kinase regulatory subunit; [GO:0016538] cyclin-dependent protein serine/threonine kinase regulator activity; [GO:0007049] cell cycle; [PTHR23415] CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 162.94 0.6790 162 Mapoly0143s0033 - 162.94 0.5781 163 Mapoly0014s0217 [GO:0005515] protein binding; [KOG0322] G-protein beta subunit-like protein GNB1L, contains WD repeats; [PTHR19854:SF1] GB DEF: GUANINE NUCLEOTIDE-BINDING PROTEIN BETA SUBUNIT-LIKE PROTEIN 1 G PROTEIN BETA-S; [PTHR19854] TRANSDUCIN BETA-LIKE 3; [PF00400] WD domain, G-beta repeat 163.53 0.6514 164 Mapoly0065s0055 [KOG3077] Uncharacterized conserved protein; [PF03556] Cullin binding; [PF14555] UBA-like domain; [PTHR12281] RP42 RELATED 164.33 0.6238 165 Mapoly0066s0078 [GO:0034453] microtubule anchoring; [PTHR15431:SF3] FGFR1 ONCOGENE PARTNER; [PTHR15431] FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN; [GO:0005815] microtubule organizing center; [PF09398] FOP N terminal dimerisation domain 164.52 0.6578 166 Mapoly0003s0236 [PTHR11746] O-METHYLTRANSFERASE; [GO:0005737] cytoplasm; [PF02545] Maf-like protein; [KOG1509] Predicted nucleic acid-binding protein ASMTL; [K06287] septum formation protein 165.89 0.7102 167 Mapoly0113s0030 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [K14440] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:3.6.4.12]; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [3.6.4.12] DNA helicase.; [KOG1000] Chromatin remodeling protein HARP/SMARCAL1, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF43] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A-LIKE PROTEIN 1 166.28 0.6384 168 Mapoly0029s0079 [GO:0042393] histone binding; [PF12165] Domain of unknown function (DUF3594); [GO:0006355] regulation of transcription, DNA-dependent; [KOG1632] Uncharacterized PHD Zn-finger protein; [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR12321] CPG BINDING PROTEIN 166.85 0.6768 169 Mapoly0061s0107 [GO:0003677] DNA binding; [KOG0483] Transcription factor HEX, contains HOX and HALZ domains; [PF00046] Homeobox domain; [PF08670] MEKHLA domain; [PF01852] START domain; [PTHR24326] FAMILY NOT NAMED; [GO:0008289] lipid binding; [K09338] homeobox-leucine zipper protein 167.51 0.6487 170 Mapoly0077s0024 [PTHR21596] RIBONUCLEASE P PROTEIN SUBUNIT P38-RELATED 168.73 0.6522 171 Mapoly0073s0081 [K11876] proteasome assembly chaperone 2; [KOG3112] Uncharacterized conserved protein; [PF09754] PAC2 family; [PTHR12970] TUMOR NECROSIS FACTOR SUPERFAMILY, MEMBER 5-INDUCED PROTEIN 1 (CLAST3) 170.01 0.6810 172 Mapoly0013s0069 [PF08263] Leucine rich repeat N-terminal domain; [PF12819] Carbohydrate-binding protein of the ER; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 170.24 0.5442 173 Mapoly0090s0046 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [K11251] histone H2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 170.68 0.6913 174 Mapoly0044s0074 - 171.04 0.6322 175 Mapoly0094s0008 [PTHR21100:SF9] SUBFAMILY NOT NAMED; [PTHR21100] FAMILY NOT NAMED; [GO:0016272] prefoldin complex; [KOG1760] Molecular chaperone Prefoldin, subunit 4; [GO:0006457] protein folding; [K09550] prefoldin subunit 4; [GO:0051082] unfolded protein binding; [PF01920] Prefoldin subunit 172.75 0.6577 176 Mapoly0011s0101 - 174.72 0.6990 177 Mapoly0052s0086 [PF05641] Agenet domain; [PTHR31917] FAMILY NOT NAMED 176.83 0.6911 178 Mapoly0001s0037 [PTHR12864] RAN BINDING PROTEIN 9-RELATED; [KOG2659] LisH motif-containing protein; [PF10607] CTLH/CRA C-terminal to LisH motif domain 179.60 0.6290 179 Mapoly0060s0008 [PF07748] Glycosyl hydrolases family 38 C-terminal domain; [GO:0015923] mannosidase activity; [PTHR11607] ALPHA-MANNOSIDASE; [GO:0004559] alpha-mannosidase activity; [GO:0006013] mannose metabolic process; [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [PF09261] Alpha mannosidase, middle domain; [GO:0005975] carbohydrate metabolic process; [GO:0008270] zinc ion binding; [K01231] alpha-mannosidase II [EC:3.2.1.114]; [PF01074] Glycosyl hydrolases family 38 N-terminal domain; [PTHR11607:SF4] MANNOSIDASE ALPHA CLASS 2A; [3.2.1.114] Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase.; [KOG1958] Glycosyl hydrolase, family 38 - alpha-mannosidase 179.61 0.6387 180 Mapoly0051s0073 [PF14675] FANCI solenoid 1; [PTHR21818:SF0] SUBFAMILY NOT NAMED; [PF14680] FANCI helical domain 2; [KOG4553] Uncharacterized conserved protein; [K10895] fanconi anemia group I protein; [PF14679] FANCI helical domain 1; [GO:0006281] DNA repair; [PF14678] FANCI solenoid 4; [PTHR21818] BC025462 PROTEIN; [PF14676] FANCI solenoid 2 179.96 0.6859 181 Mapoly0083s0043 [GO:0008375] acetylglucosaminyltransferase activity; [GO:0016020] membrane; [PF02485] Core-2/I-Branching enzyme; [PTHR31042] FAMILY NOT NAMED 180.47 0.6827 182 Mapoly0009s0203 - 181.46 0.6623 183 Mapoly0061s0115 [PTHR23079] RNA-DEPENDENT RNA POLYMERASE; [GO:0003968] RNA-directed RNA polymerase activity; [PTHR23079:SF1] RNA-DEPENDENT RNA POLYMERASE; [KOG0988] RNA-directed RNA polymerase QDE-1 required for posttranscriptional gene silencing and RNA interference; [PF05183] RNA dependent RNA polymerase 181.71 0.5830 184 Mapoly0011s0129 [KOG0131] Splicing factor 3b, subunit 4; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [PTHR24011] FAMILY NOT NAMED; [PF07145] Ataxin-2 C-terminal region; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 182.27 0.6496 185 Mapoly0102s0018 [PF06825] Heat shock factor binding protein 1; [KOG4117] Heat shock factor binding protein; [PTHR19424] HEAT SHOCK FACTOR BINDING PROTEIN 1 183.53 0.7109 186 Mapoly0001s0378 [PTHR32086] FAMILY NOT NAMED; [K10891] fanconi anemia group D2 protein; [GO:0006281] DNA repair; [KOG4712] Uncharacterized conserved protein; [PF14631] Fanconi anaemia protein FancD2 nuclease 183.65 0.6838 187 Mapoly0006s0287 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02209] minichromosome maintenance protein 5 (cell division control protein 46); [PTHR11630:SF42] DNA REPLICATION LICENSING FACTOR MCM5; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain; [KOG0481] DNA replication licensing factor, MCM5 component 183.74 0.6898 188 Mapoly0011s0132 - 184.00 0.6665 189 Mapoly0171s0023 [GO:0016787] hydrolase activity; [KOG2839] Diadenosine and diphosphoinositol polyphosphate phosphohydrolase; [PTHR12629] DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE; [PF00293] NUDIX domain 185.31 0.6143 190 Mapoly0054s0054 [KOG3276] Uncharacterized conserved protein, contains YggU domain; [PTHR13420:SF1] gb def: y66d12a.8.p [caenorhabditis elegans]; [K09131] hypothetical protein; [PTHR13420] UNCHARACTERIZED; [PF02594] Uncharacterised ACR, YggU family COG1872 185.46 0.5516 191 Mapoly0044s0032 [PTHR12299] HYALURONIC ACID-BINDING PROTEIN 4; [PF09598] Stm1; [KOG2945] Predicted RNA-binding protein; [PF04774] Hyaluronan / mRNA binding family; [K13199] plasminogen activator inhibitor 1 RNA-binding protein 185.62 0.6762 192 Mapoly0099s0054 [GO:0035064] methylated histone residue binding; [PTHR10333] INHIBITOR OF GROWTH PROTEIN; [PF12998] Inhibitor of growth proteins N-terminal histone-binding; [PF00628] PHD-finger; [GO:0005515] protein binding; [KOG1973] Chromatin remodeling protein, contains PHD Zn-finger; [GO:0016568] chromatin modification; [GO:0005634] nucleus 186.93 0.6562 193 Mapoly0001s0126 [PF05216] UNC-50 family; [PTHR12841] FAMILY NOT NAMED; [KOG3012] Uncharacterized conserved protein 192.35 0.6402 194 Mapoly0023s0045 [KOG3264] Uncharacterized conserved protein; [GO:0006357] regulation of transcription from RNA polymerase II promoter; [PTHR13321] MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 18; [GO:0016592] mediator complex; [GO:0001104] RNA polymerase II transcription cofactor activity; [PTHR13321:SF2] SUBFAMILY NOT NAMED; [PF09637] Med18 protein 193.49 0.5677 195 Mapoly0004s0128 [GO:0005524] ATP binding; [K08864] tousled-like kinase [EC:2.7.11.1]; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PTHR22974] MIXED LINEAGE PROTEIN KINASE; [KOG1151] Tousled-like protein kinase 194.55 0.6744 196 Mapoly0031s0144 [PTHR19375] HEAT SHOCK PROTEIN 70KDA; [K09490] heat shock 70kDa protein 5; [KOG0100] Molecular chaperones GRP78/BiP/KAR2, HSP70 superfamily; [PF00012] Hsp70 protein 195.32 0.6115 197 Mapoly0010s0124 [K14320] aladin; [KOG2139] WD40 repeat protein; [GO:0005515] protein binding; [PTHR14494] ALADIN/ADRACALIN/AAAS; [PTHR14494:SF0] SUBFAMILY NOT NAMED; [PF00400] WD domain, G-beta repeat 198.99 0.6588 198 Mapoly0002s0311 [K01669] deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]; [GO:0003913] DNA photolyase activity; [KOG0133] Deoxyribodipyrimidine photolyase/cryptochrome; [PTHR11455] CRYPTOCHROME; [PF00875] DNA photolyase; [PF03441] FAD binding domain of DNA photolyase; [GO:0006281] DNA repair; [4.1.99.3] Deoxyribodipyrimidine photo-lyase. 199.45 0.6386 199 Mapoly0073s0079 [GO:0046907] intracellular transport; [GO:0005643] nuclear pore; [PTHR23138] RAN BINDING PROTEIN; [PTHR23138:SF46] ABR034WP; [PF00638] RanBP1 domain; [PF08911] NUP50 (Nucleoporin 50 kDa) 199.71 0.6735 200 Mapoly0032s0097 [PF13837] Myb/SANT-like DNA-binding domain 200.11 0.6303