Guide Gene
- Gene ID
- Mapoly0039s0120
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [KOG1805] DNA replication helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PTHR10887:SF14] DNA2-LIKE HELICASE; [3.6.4.12] DNA helicase.; [PF13086] AAA domain; [GO:0033567] DNA replication, Okazaki fragment processing; [PF01930] Domain of unknown function DUF83; [GO:0017108] 5'-flap endonuclease activity; [GO:0043142] single-stranded DNA-dependent ATPase activity; [PF13087] AAA domain; [PF08696] DNA replication factor Dna2; [K10742] DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12]
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0039s0120 [KOG1805] DNA replication helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PTHR10887:SF14] DNA2-LIKE HELICASE; [3.6.4.12] DNA helicase.; [PF13086] AAA domain; [GO:0033567] DNA replication, Okazaki fragment processing; [PF01930] Domain of unknown function DUF83; [GO:0017108] 5'-flap endonuclease activity; [GO:0043142] single-stranded DNA-dependent ATPase activity; [PF13087] AAA domain; [PF08696] DNA replication factor Dna2; [K10742] DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12] 0.00 1.0000 1 Mapoly0189s0011 [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain 4.12 0.8492 2 Mapoly0001s0378 [PTHR32086] FAMILY NOT NAMED; [K10891] fanconi anemia group D2 protein; [GO:0006281] DNA repair; [KOG4712] Uncharacterized conserved protein; [PF14631] Fanconi anaemia protein FancD2 nuclease 4.24 0.8313 3 Mapoly0013s0201 [PTHR23269:SF0] SUBFAMILY NOT NAMED; [KOG0128] RNA-binding protein SART3 (RRM superfamily); [PF05391] Lsm interaction motif; [GO:0003676] nucleic acid binding; [PTHR23269] RIBONUCLEOPROTEIN-RELATED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 5.74 0.8221 4 Mapoly0052s0086 [PF05641] Agenet domain; [PTHR31917] FAMILY NOT NAMED 12.49 0.8170 5 Mapoly0039s0001 - 13.00 0.7869 6 Mapoly0001s0208 [PTHR31431] FAMILY NOT NAMED; [KOG4833] Uncharacterized conserved protein; [K14311] nuclear pore complex protein Nup188; [PF10487] Nucleoporin subcomplex protein binding to Pom34 14.00 0.8017 7 Mapoly0067s0049 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF00580] UvrD/REP helicase N-terminal domain; [PF13361] UvrD-like helicase C-terminal domain; [GO:0016787] hydrolase activity; [GO:0004003] ATP-dependent DNA helicase activity; [PTHR11070] UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER 16.12 0.7745 8 Mapoly0197s0017 [PTHR10751] GUANYLATE BINDING PROTEIN; [KOG1003] Actin filament-coating protein tropomyosin; [PTHR10751:SF2] GUANYLATE BINDING PROTEIN; [PF02263] Guanylate-binding protein, N-terminal domain; [GO:0003924] GTPase activity; [GO:0005525] GTP binding; [PF02841] Guanylate-binding protein, C-terminal domain 16.31 0.7576 9 Mapoly0029s0003 [KOG1824] TATA-binding protein-interacting protein; [PTHR12696] TIP120; [PF08623] TATA-binding protein interacting (TIP20); [PF13646] HEAT repeats 19.90 0.7903 10 Mapoly0120s0004 [PF00488] MutS domain V; [GO:0005524] ATP binding; [K08735] DNA mismatch repair protein MSH2; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PTHR11361:SF35] MUTS HOMOLOG 2, MSH2; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III; [KOG0219] Mismatch repair ATPase MSH2 (MutS family); [PF05190] MutS family domain IV 20.20 0.7916 11 Mapoly0091s0014 [PTHR12596:SF1] GB DEF: T27C4.14 PROTEIN; [PTHR12596] EXPORTIN 4,7-RELATED; [KOG4541] Nuclear transport receptor exportin 4 (importin beta superfamily) 20.35 0.7816 12 Mapoly0026s0077 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [2.7.11.1] Non-specific serine/threonine protein kinase.; [PF08064] UME (NUC010) domain; [PF00454] Phosphatidylinositol 3- and 4-kinase; [K06640] ataxia telangiectasia and Rad3 related [EC:2.7.11.1]; [GO:0004674] protein serine/threonine kinase activity; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [KOG0890] Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination 20.49 0.7834 13 Mapoly0006s0290 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR10670:SF0] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A; [GO:0000166] nucleotide binding; [GO:0008270] zinc ion binding; [2.7.7.7] DNA-directed DNA polymerase.; [KOG1798] DNA polymerase epsilon, catalytic subunit A; [PF08490] Domain of unknown function (DUF1744); [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF00136] DNA polymerase family B; [GO:0008622] epsilon DNA polymerase complex; [K02324] DNA polymerase epsilon subunit 1 [EC:2.7.7.7]; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10670] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A 20.93 0.8026 14 Mapoly0010s0094 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [PF00454] Phosphatidylinositol 3- and 4-kinase; [KOG0889] Histone acetyltransferase SAGA, TRRAP/TRA1 component, PI-3 kinase superfamily; [PTHR11139:SF1] ATM-RELATED; [K08874] transformation/transcription domain-associated protein; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED 22.58 0.7909 15 Mapoly0033s0057 [2.3.1.-] Transferring groups other than amino-acyl groups.; [PTHR11076:SF1] ESTABLISHMENT OF COHESION 1 (ECO1) HOMOLOG; [PF13880] ESCO1/2 acetyl-transferase; [PF13878] zinc-finger of acetyl-transferase ESCO; [KOG3014] Protein involved in establishing cohesion between sister chromatids during DNA replication; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [K11268] N-acetyltransferase [EC:2.3.1.-] 22.80 0.8052 16 Mapoly0114s0009 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [PF00514] Armadillo/beta-catenin-like repeat; [GO:0005515] protein binding; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [KOG0240] Kinesin (SMY1 subfamily); [GO:0008017] microtubule binding; [PTHR24115:SF221] SUBFAMILY NOT NAMED; [GO:0003777] microtubule motor activity 24.68 0.7690 17 Mapoly0045s0096 [K08775] breast cancer 2 susceptibility protein; [PTHR11289] BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2; [GO:0003697] single-stranded DNA binding; [PF09169] BRCA2, helical; [PTHR11289:SF0] SUBFAMILY NOT NAMED; [GO:0006281] DNA repair; [PF09103] BRCA2, oligonucleotide/oligosaccharide-binding, domain 1; [GO:0000724] double-strand break repair via homologous recombination; [GO:0006310] DNA recombination 29.66 0.7216 18 Mapoly0067s0068 [KOG2266] Chromatin-associated protein Dek and related proteins, contains SAP DNA binding domain; [PTHR13468:SF1] DEK ONCOGENE; [PF08766] DEK C terminal domain; [PTHR13468] DEK PROTEIN 32.25 0.7824 19 Mapoly0102s0001 [K06228] fused [EC:2.7.11.1]; [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR22983:SF6] MAPK KINASE 2-RELATED; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [KOG0598] Ribosomal protein S6 kinase and related proteins; [PF13646] HEAT repeats 34.64 0.7890 20 Mapoly0015s0164 [GO:0003677] DNA binding; [PF02362] B3 DNA binding domain; [PTHR31391] FAMILY NOT NAMED 34.70 0.7731 21 Mapoly0209s0008 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF67] DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 35.50 0.7913 22 Mapoly0005s0067 [PTHR15242:SF0] SUBFAMILY NOT NAMED; [PTHR15242] SPLICING FACTOR, ARGININE/SERINE-RICH 2,RNAP C-TERM INTERACTING PROTEIN; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 37.11 0.7820 23 Mapoly0044s0071 [PTHR12827] MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; [PF12859] Anaphase-promoting complex subunit 1; [K03348] anaphase-promoting complex subunit 1; [KOG1858] Anaphase-promoting complex (APC), subunit 1 (meiotic check point regulator/Tsg24); [GO:0005680] anaphase-promoting complex 40.47 0.7548 24 Mapoly0004s0169 [GO:0003677] DNA binding; [GO:0006338] chromatin remodeling; [GO:0005524] ATP binding; [PF09110] HAND; [K11654] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]; [GO:0043044] ATP-dependent chromatin remodeling; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [GO:0005634] nucleus; [PTHR10799:SF73] ISWI CHROMATIN-REMODELING COMPLEX ATPASE ISW1; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [KOG0385] Chromatin remodeling complex WSTF-ISWI, small subunit; [GO:0003676] nucleic acid binding; [GO:0031491] nucleosome binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [PF09111] SLIDE 40.99 0.7797 25 Mapoly0033s0129 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0003910] DNA ligase (ATP) activity; [PF04679] ATP dependent DNA ligase C terminal region; [PTHR10459] DNA LIGASE; [K10747] DNA ligase 1 [EC:6.5.1.1]; [PF01068] ATP dependent DNA ligase domain; [6.5.1.1] DNA ligase (ATP).; [GO:0006281] DNA repair; [PF04675] DNA ligase N terminus; [PTHR10459:SF10] DNA LIGASE I; [GO:0006310] DNA recombination; [KOG0967] ATP-dependent DNA ligase I 42.45 0.7426 26 Mapoly0001s0472 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED 44.72 0.7810 27 Mapoly0027s0147 [PTHR12585] SCC1 / RAD21 FAMILY MEMBER; [PF04824] Conserved region of Rad21 / Rec8 like protein; [GO:0005515] protein binding; [PF04825] N terminus of Rad21 / Rec8 like protein; [K06670] cohesin complex subunit SCC1; [GO:0000228] nuclear chromosome; [KOG1213] Sister chromatid cohesion complex Cohesin, subunit RAD21/SCC1 46.30 0.7644 28 Mapoly0038s0027 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PTHR10629:SF11] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF12047] Cytosine specific DNA methyltransferase replication foci domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 46.62 0.7564 29 Mapoly0034s0119 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 47.03 0.7857 30 Mapoly0053s0080 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PF12230] Pre-mRNA splicing factor PRP21 like protein; [GO:0005515] protein binding; [PTHR15316:SF1] SPLICEOSOME ASSOCIATED PROTEIN 114; [PF00240] Ubiquitin family; [K12825] splicing factor 3A subunit 1; [PTHR15316] SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED; [PF01805] Surp module; [KOG0007] Splicing factor 3a, subunit 1 48.17 0.7567 31 Mapoly0036s0123 [GO:0000922] spindle pole; [PTHR19302:SF13] GAMMA-TUBULIN COMPLEX COMPONENT 2 (GCP-2); [PF04130] Spc97 / Spc98 family; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [KOG2001] Gamma-tubulin complex, DGRIP84/SPC97 component 50.73 0.7794 32 Mapoly0130s0046 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF14493] Helix-turn-helix domain; [PF09382] RQC domain; [K10900] werner syndrome ATP-dependent helicase [EC:3.6.4.12]; [KOG0353] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 52.96 0.7640 33 Mapoly0030s0102 [PF08317] Spc7 kinetochore protein 53.62 0.7772 34 Mapoly0011s0202 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain 54.27 0.7810 35 Mapoly0011s0137 [K03504] DNA polymerase delta subunit 3; [GO:0006260] DNA replication; [PTHR17598] FAMILY NOT NAMED; [PF09507] DNA polymerase subunit Cdc27; [GO:0005634] nucleus 54.70 0.7639 36 Mapoly0020s0107 [KOG4626] O-linked N-acetylglucosamine transferase OGT; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13432] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat; [PF13844] Glycosyl transferase family 41; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR 56.57 0.7449 37 Mapoly0043s0044 [PTHR13257:SF0] SUBFAMILY NOT NAMED; [K14318] nuclear pore complex protein Nup88; [PF10168] Nuclear pore component; [KOG4460] Nuclear pore complex, Nup88/rNup84 component; [PTHR13257] NUCLEOPORIN NUP84-RELATED 58.57 0.7452 38 Mapoly0113s0048 [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [KOG1408] WD40 repeat protein; [PF00400] WD domain, G-beta repeat 59.40 0.7767 39 Mapoly0162s0013 [PF00929] Exonuclease; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [PTHR11361:SF34] DNA MISMATCH REPAIR PROTEIN MUTS; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [KOG0218] Mismatch repair MSH3; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 60.52 0.7605 40 Mapoly0051s0023 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III 61.64 0.7753 41 Mapoly0004s0286 [PTHR12663:SF0] SUBFAMILY NOT NAMED; [K11267] sister chromatid cohesion protein PDS5; [PTHR12663] ANDROGEN INDUCED INHIBITOR OF PROLIFERATION (AS3) / PDS5-RELATED; [KOG1525] Sister chromatid cohesion complex Cohesin, subunit PDS5 62.00 0.7654 42 Mapoly0118s0005 [GO:0008233] peptidase activity; [3.4.22.49] Separase.; [K02365] separase [EC:3.4.22.49]; [GO:0005634] nucleus; [PF03568] Peptidase family C50; [GO:0006508] proteolysis; [PTHR12792] EXTRA SPINDLE POLES 1-RELATED 62.93 0.7666 43 Mapoly0028s0110 [GO:0005524] ATP binding; [PTHR23069] TAT-BINDING HOMOLOG 7; [PTHR23069:SF0] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [PF00439] Bromodomain; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0732] AAA+-type ATPase containing the bromodomain 63.99 0.7568 44 Mapoly0159s0020 [K05544] tRNA-dihydrouridine synthase 3 [EC:1.-.-.-]; [GO:0050660] flavin adenine dinucleotide binding; [GO:0055114] oxidation-reduction process; [PTHR11082:SF8] TRNA-DIHYDROURIDINE SYNTHASE 3; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PF01207] Dihydrouridine synthase (Dus); [KOG2333] Uncharacterized conserved protein; [GO:0008033] tRNA processing; [PTHR11082] TRNA-DIHYDROURIDINE SYNTHASE; [GO:0046872] metal ion binding; [GO:0017150] tRNA dihydrouridine synthase activity; [1.-.-.-] Oxidoreductases. 64.00 0.7345 45 Mapoly0003s0057 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination 64.48 0.7741 46 Mapoly0069s0084 [3.6.5.5] Dynamin GTPase.; [KOG0446] Vacuolar sorting protein VPS1, dynamin, and related proteins; [K01528] dynamin GTPase [EC:3.6.5.5]; [PF02212] Dynamin GTPase effector domain; [PF00350] Dynamin family; [PTHR11566] DYNAMIN; [GO:0003924] GTPase activity; [PTHR11566:SF21] SUBFAMILY NOT NAMED; [GO:0005525] GTP binding; [PF01031] Dynamin central region 65.18 0.7302 47 Mapoly0074s0001 [PF03810] Importin-beta N-terminal domain; [PF08767] CRM1 C terminal; [KOG2020] Nuclear transport receptor CRM1/MSN5 (importin beta superfamily); [PTHR11223] EXPORTIN 1/5; [GO:0006886] intracellular protein transport; [PTHR11223:SF2] EXPORTIN 1 (CHROMOSOME REGION MAINTENANCE PROTEIN 1); [K14290] exportin-1; [GO:0008536] Ran GTPase binding; [PF08389] Exportin 1-like protein 66.81 0.6906 48 Mapoly0091s0056 [PF05918] Apoptosis inhibitory protein 5 (API5); [KOG2213] Apoptosis inhibitor 5/fibroblast growth factor 2-interacting factor 2, and related proteins; [PTHR12758] APOPTOSIS INHIBITOR 5-RELATED 67.75 0.7443 49 Mapoly0189s0010 [PTHR15272:SF0] SUBFAMILY NOT NAMED; [PF12253] Chromatin assembly factor 1 subunit A; [PTHR15272] CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A (CAF-1 SUBUNIT A) 67.84 0.7372 50 Mapoly0074s0043 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [GO:0003729] mRNA binding 68.59 0.7478 51 Mapoly0008s0250 [PTHR24007] BRCA1-ASSOCIATED PROTEIN; [PF00917] MATH domain; [GO:0005515] protein binding; [GO:0006281] DNA repair; [PF14631] Fanconi anaemia protein FancD2 nuclease; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 68.98 0.7357 52 Mapoly0051s0073 [PF14675] FANCI solenoid 1; [PTHR21818:SF0] SUBFAMILY NOT NAMED; [PF14680] FANCI helical domain 2; [KOG4553] Uncharacterized conserved protein; [K10895] fanconi anemia group I protein; [PF14679] FANCI helical domain 1; [GO:0006281] DNA repair; [PF14678] FANCI solenoid 4; [PTHR21818] BC025462 PROTEIN; [PF14676] FANCI solenoid 2 70.04 0.7510 53 Mapoly0037s0093 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG4280] Kinesin-like protein; [PTHR24115:SF87] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [PF12711] Kinesin motor; [GO:0003777] microtubule motor activity 70.10 0.7425 54 Mapoly0061s0085 [PF14868] Domain of unknown function (DUF4487) 70.63 0.7525 55 Mapoly0122s0062 [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 71.97 0.7631 56 Mapoly0113s0037 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [KOG2577] Transcription factor E2F/dimerization partner (TDP); [PTHR12081] TRANSCRIPTION FACTOR E2F 73.08 0.7359 57 Mapoly0104s0019 [KOG2242] Scaffold/matrix specific factor hnRNP-U/SAF-A, contains SPRY domain; [PTHR12381:SF13] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [PF13671] AAA domain; [PF00622] SPRY domain; [PTHR12381] RIBONUCLEOPROTEIN 76.95 0.7347 58 Mapoly0070s0053 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF09382] RQC domain; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [K10901] bloom syndrome protein [EC:3.6.4.12]; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 77.07 0.7519 59 Mapoly0054s0064 [PF03178] CPSF A subunit region; [PF10433] Mono-functional DNA-alkylating methyl methanesulfonate N-term; [PTHR10644:SF3] DNA DAMAGE-BINDING PROTEIN 1 (DAMAGE-SPECIFIC DNA-BINDING PROTEIN 1)(UV-DAMAGED DNA-BINDING FACTOR); [K10610] DNA damage-binding protein 1; [GO:0005634] nucleus; [PTHR10644] DNA REPAIR/RNA PROCESSING CPSF FAMILY; [KOG1897] Damage-specific DNA binding complex, subunit DDB1; [GO:0003676] nucleic acid binding 77.36 0.6706 60 Mapoly0098s0032 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [PF11721] Di-glucose binding within endoplasmic reticulum; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 78.23 0.7624 61 Mapoly0105s0028 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 79.95 0.7316 62 Mapoly0007s0100 [PTHR15828] CYTOKINE RECEPTOR-LIKE FACTOR 3 80.60 0.7403 63 Mapoly0009s0056 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PF08311] Mad3/BUB1 homology region 1; [K02178] checkpoint serine/threonine-protein kinase [EC:2.7.11.1]; [KOG1166] Mitotic checkpoint serine/threonine protein kinase; [PTHR14030] MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 81.41 0.7487 64 Mapoly0061s0078 [KOG1361] Predicted hydrolase involved in interstrand cross-link repair; [PTHR23240] DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; [PF12706] Beta-lactamase superfamily domain; [PF07522] DNA repair metallo-beta-lactamase; [PF00536] SAM domain (Sterile alpha motif) 82.67 0.7317 65 Mapoly0004s0006 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [KOG0600] Cdc2-related protein kinase; [PTHR24056] CELL DIVISION PROTEIN KINASE 82.70 0.7117 66 Mapoly0029s0012 [GO:0005524] ATP binding; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [KOG0329] ATP-dependent RNA helicase; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding 83.07 0.7491 67 Mapoly0045s0049 - 84.33 0.6983 68 Mapoly0111s0003 - 86.32 0.7129 69 Mapoly0073s0063 [GO:0016020] membrane; [GO:0005524] ATP binding; [GO:0017038] protein import; [PF07516] SecA Wing and Scaffold domain; [PTHR30612] SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM; [PF07517] SecA DEAD-like domain; [PF01043] SecA preprotein cross-linking domain; [K03070] preprotein translocase subunit SecA 87.11 0.6328 70 Mapoly0060s0056 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 87.87 0.7319 71 Mapoly0013s0006 [GO:0008270] zinc ion binding; [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PTHR23336] ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3.; [PF07496] CW-type Zinc Finger 89.33 0.7179 72 Mapoly0044s0074 - 90.86 0.6718 73 Mapoly0042s0123 [K12875] apoptotic chromatin condensation inducer in the nucleus; [GO:0003676] nucleic acid binding; [PTHR14127] APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; [PF02037] SAP domain 93.47 0.7441 74 Mapoly0004s0250 [GO:0005643] nuclear pore; [PF07817] GLE1-like protein; [GO:0016973] poly(A)+ mRNA export from nucleus; [KOG2412] Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor; [PTHR12960:SF0] SUBFAMILY NOT NAMED; [PTHR12960] GLE-1-RELATED 93.84 0.7283 75 Mapoly0002s0007 [GO:0003723] RNA binding; [GO:0001522] pseudouridine synthesis; [GO:0009451] RNA modification; [GO:0009982] pseudouridine synthase activity; [PF00849] RNA pseudouridylate synthase; [PTHR21600] RIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE SYNTHASE B; [PF01479] S4 domain 94.99 0.6643 76 Mapoly0013s0109 [PF00514] Armadillo/beta-catenin-like repeat; [PF00651] BTB/POZ domain; [GO:0005515] protein binding; [KOG0166] Karyopherin (importin) alpha; [PTHR23315] BETA CATENIN-RELATED ARMADILLO REPEAT-CONTAINING 94.99 0.7126 77 Mapoly0091s0060 - 98.41 0.6871 78 Mapoly0010s0152 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PTHR13561:SF5] DNA REPLICATION REGULATOR DPB11; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 98.44 0.7393 79 Mapoly0001s0391 [GO:0005634] nucleus; [PF05965] F/Y rich C-terminus 98.63 0.7304 80 Mapoly0185s0017 [GO:0030915] Smc5-Smc6 complex; [PF08746] RING-like domain; [KOG4718] Non-SMC (structural maintenance of chromosomes) element 1 protein (NSE1); [PTHR20973] NON-SMC ELEMENT 1-RELATED; [PF07574] Nse1 non-SMC component of SMC5-6 complex; [GO:0006281] DNA repair; [PTHR20973:SF0] SUBFAMILY NOT NAMED 98.98 0.7316 81 Mapoly0060s0012 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [K11498] centromeric protein E; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 99.22 0.7411 82 Mapoly0094s0033 [GO:0016567] protein ubiquitination; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [KOG0314] Predicted E3 ubiquitin ligase; [GO:0005634] nucleus; [PF08783] DWNN domain; [GO:0003676] nucleic acid binding; [GO:0004842] ubiquitin-protein ligase activity; [PTHR15439] RETINOBLASTOMA-BINDING PROTEIN 6; [PF04564] U-box domain 100.32 0.6749 83 Mapoly0001s0449 [GO:0006355] regulation of transcription, DNA-dependent; [PF04153] NOT2 / NOT3 / NOT5 family; [GO:0005634] nucleus; [K12605] CCR4-NOT transcription complex subunit 2; [PTHR23326] CCR4 NOT-RELATED 100.73 0.6701 84 Mapoly0001s0044 [PTHR31110] FAMILY NOT NAMED 101.02 0.7326 85 Mapoly0132s0046 [PF00855] PWWP domain; [PTHR12550] HEPATOMA-DERIVED GROWTH FACTOR-RELATED; [PTHR12550:SF5] UNCHARACTERIZED 101.29 0.7065 86 Mapoly0108s0036 [GO:0030001] metal ion transport; [3.6.3.4] Cu(2+)-exporting ATPase.; [GO:0000166] nucleotide binding; [K01533] Cu2+-exporting ATPase [EC:3.6.3.4]; [PF00702] haloacid dehalogenase-like hydrolase; [PTHR24093] FAMILY NOT NAMED; [PF00403] Heavy-metal-associated domain; [GO:0046872] metal ion binding; [KOG0207] Cation transport ATPase; [PF00122] E1-E2 ATPase 101.85 0.4919 87 Mapoly0033s0105 [PF03470] XS zinc finger domain; [PTHR21596] RIBONUCLEASE P PROTEIN SUBUNIT P38-RELATED; [PF03468] XS domain; [GO:0031047] gene silencing by RNA 104.44 0.6590 88 Mapoly0036s0107 [K09422] myb proto-oncogene protein, plant; [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding; [PF13921] Myb-like DNA-binding domain 104.50 0.7309 89 Mapoly0069s0029 [PTHR10795:SF157] UNCHARACTERIZED; [KOG1114] Tripeptidyl peptidase II; [K01280] tripeptidyl-peptidase II [EC:3.4.14.10]; [GO:0004252] serine-type endopeptidase activity; [3.4.14.10] Tripeptidyl-peptidase II.; [PF00082] Subtilase family; [PF12580] Tripeptidyl peptidase II; [GO:0006508] proteolysis; [PTHR10795] PROPROTEIN CONVERTASE SUBTILISIN/KEXIN 107.37 0.6957 90 Mapoly0015s0206 [PF05236] Transcription initiation factor TFIID component TAF4 family; [GO:0006352] DNA-dependent transcription, initiation; [PTHR15138] FAMILY NOT NAMED; [PF12174] RCD1-SRO-TAF4 (RST) plant domain; [GO:0005669] transcription factor TFIID complex 107.97 0.7162 91 Mapoly0033s0098 [PTHR16047] RFWD3 PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PTHR16047:SF7] RFWD3 PROTEIN-RELATED; [KOG1645] RING-finger-containing E3 ubiquitin ligase 108.13 0.7218 92 Mapoly0086s0067 [GO:0005524] ATP binding; [GO:0032300] mismatch repair complex; [KOG1979] DNA mismatch repair protein - MLH1 family; [PTHR10073] DNA MISMATCH REPAIR PROTEIN (MLH, PMS, MUTL); [PTHR10073:SF12] DNA MISMATCH REPAIR PROTEIN MUTL; [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [K08734] DNA mismatch repair protein MLH1; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01119] DNA mismatch repair protein, C-terminal domain 108.49 0.6550 93 Mapoly0042s0007 [GO:0003677] DNA binding; [K02213] cell division control protein 6; [KOG2227] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase; [PF13401] AAA domain; [PF01429] Methyl-CpG binding domain; [GO:0005634] nucleus; [PF09079] CDC6, C terminal; [PTHR10763] CELL DIVISION CONTROL PROTEIN 6-RELATED 108.66 0.7211 94 Mapoly0001s0355 [GO:0016020] membrane; [GO:0004222] metalloendopeptidase activity; [PF01457] Leishmanolysin; [PF07974] EGF-like domain; [KOG2556] Leishmanolysin-like peptidase (Peptidase M8 family); [3.4.24.36] Leishmanolysin.; [GO:0007155] cell adhesion; [GO:0006508] proteolysis; [K01404] leishmanolysin [EC:3.4.24.36]; [PTHR10942] LEISHMANOLYSIN-LIKE PEPTIDASE 108.93 0.7079 95 Mapoly0001s0369 [K12879] THO complex subunit 2; [PF11262] Transcription factor/nuclear export subunit protein 2; [PTHR21597] THO2 PROTEIN; [PF11732] Transcription- and export-related complex subunit; [PTHR21597:SF0] SUBFAMILY NOT NAMED; [KOG1874] KEKE-like motif-containing transcription regulator (Rlr1)/suppressor of sin4 109.11 0.7356 96 Mapoly0038s0098 [K03351] anaphase-promoting complex subunit 4; [PF12896] Anaphase-promoting complex, cyclosome, subunit 4; [KOG4640] Anaphase-promoting complex (APC), subunit 4; [GO:0030071] regulation of mitotic metaphase/anaphase transition; [PF12894] Anaphase-promoting complex subunit 4 WD40 domain; [PTHR13260] ANAPHASE PROMOTING COMPLEX SUBUNIT 4 (APC4) (CYCLOSOME SUBUNIT 4); [GO:0005680] anaphase-promoting complex; [GO:0031145] anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 110.27 0.6858 97 Mapoly0083s0034 - 110.50 0.7055 98 Mapoly0051s0092 [GO:0007264] small GTPase mediated signal transduction; [K07975] Rho family, other; [PTHR24072] RHO FAMILY GTPASE; [KOG0393] Ras-related small GTPase, Rho type; [PF00071] Ras family; [GO:0005525] GTP binding 110.63 0.6844 99 Mapoly0005s0174 [GO:0005524] ATP binding; [KOG0933] Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E); [GO:0007076] mitotic chromosome condensation; [GO:0005515] protein binding; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0000796] condensin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PTHR18937:SF9] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC2; [K06674] structural maintenance of chromosome 2; [PF06470] SMC proteins Flexible Hinge Domain 112.19 0.7382 100 Mapoly0010s0062 [KOG2250] Glutamate/leucine/phenylalanine/valine dehydrogenases; [GO:0055114] oxidation-reduction process; [PTHR11606] GLUTAMATE DEHYDROGENASE; [GO:0016491] oxidoreductase activity; [PF00208] Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; [K00262] glutamate dehydrogenase (NADP+) [EC:1.4.1.4]; [GO:0006520] cellular amino acid metabolic process; [PTHR11606:SF4] SUBFAMILY NOT NAMED; [1.4.1.4] Glutamate dehydrogenase (NADP(+)).; [PF02812] Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 112.44 0.7170 101 Mapoly0039s0099 [PF00169] PH domain; [PTHR12092] PLECKSTRIN 112.45 0.6535 102 Mapoly0108s0031 [GO:0005524] ATP binding; [K04499] RuvB-like protein 1 (pontin 52); [KOG1942] DNA helicase, TBP-interacting protein; [PF06068] TIP49 C-terminus; [GO:0043141] ATP-dependent 5'-3' DNA helicase activity; [GO:0003678] DNA helicase activity; [PTHR11093] RUVB-RELATED REPTIN AND PONTIN 112.65 0.7137 103 Mapoly0024s0107 [PF07719] Tetratricopeptide repeat; [GO:0005515] protein binding; [PF13414] TPR repeat; [K03350] anaphase-promoting complex subunit 3; [KOG1126] DNA-binding cell division cycle control protein; [PF13181] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat; [PTHR12558] CELL DIVISION CYCLE 16,23,27; [PTHR12558:SF11] CELL DIVISION CYCLE 27; [PF12895] Anaphase-promoting complex, cyclosome, subunit 3 113.47 0.6989 104 Mapoly0028s0103 [PF01713] Smr domain; [GO:0003677] DNA binding; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K07456] DNA mismatch repair protein MutS2; [GO:0016887] ATPase activity; [PTHR11361:SF14] DNA MISMATCH REPAIR PROTEIN MUTS2; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [GO:0045910] negative regulation of DNA recombination 114.00 0.6134 105 Mapoly0153s0011 [PF13871] Helicase_C-like; [GO:0006355] regulation of transcription, DNA-dependent; [KOG1513] Nuclear helicase MOP-3/SNO (DEAD-box superfamily); [PTHR12706] STRAWBERRY NOTCH-RELATED; [PF13872] P-loop containing NTP hydrolase pore-1 115.00 0.7263 106 Mapoly0049s0040 [GO:0005524] ATP binding; [PTHR24058:SF23] DUAL-SPECIFICITY TYROSINE REGULATED PROTEIN KINASE 2; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24058] DUAL SPECIFICITY PROTEIN KINASE; [KOG0667] Dual-specificity tyrosine-phosphorylation regulated kinase; [GO:0006468] protein phosphorylation 115.16 0.7138 107 Mapoly0023s0118 [PTHR12446] TESMIN/TSO1-RELATED; [PF03638] Tesmin/TSO1-like CXC domain, cysteine-rich domain 116.19 0.7264 108 Mapoly0035s0108 [GO:0005524] ATP binding; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23074] AAA ATPASE; [KOG0740] AAA+-type ATPase; [PF09336] Vps4 C terminal oligomerisation domain; [PTHR23074:SF17] FIDGETIN LIKE-1 116.76 0.7110 109 Mapoly0051s0078 [GO:0006355] regulation of transcription, DNA-dependent; [KOG0266] WD40 repeat-containing protein; [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [PF00400] WD domain, G-beta repeat 117.98 0.7012 110 Mapoly0120s0055 [GO:0003677] DNA binding; [PTHR12486] APRATAXIN-RELATED; [PF13671] AAA domain; [PF01661] Macro domain; [GO:0006281] DNA repair; [KOG0562] Predicted hydrolase (HIT family); [PF11969] Scavenger mRNA decapping enzyme C-term binding; [GO:0033699] DNA 5'-adenosine monophosphate hydrolase activity; [PF10283] Zinc-finger (CX5CX6HX5H) motif; [3.-.-.-] Hydrolases.; [K10863] aprataxin [EC:3.-.-.-]; [PTHR12486:SF4] APRATAXIN (FORKHEAD-ASSOCIATED DOMAIN HISTIDINE-TRIAD LIKE PROTEIN) 119.51 0.5541 111 Mapoly0092s0032 [PTHR22597] POLYCOMB GROUP PROTEIN; [PTHR22597:SF0] SUBFAMILY NOT NAMED; [PF09733] VEFS-Box of polycomb protein 121.55 0.7206 112 Mapoly0031s0090 [KOG0379] Kelch repeat-containing proteins; [PF13418] Galactose oxidase, central domain; [PTHR23244] KELCH REPEAT DOMAIN; [PF13415] Galactose oxidase, central domain 121.59 0.7252 113 Mapoly0131s0010 [PTHR15921:SF3] SUBFAMILY NOT NAMED; [KOG2071] mRNA cleavage and polyadenylation factor I/II complex, subunit Pcf11; [PF04818] RNA polymerase II-binding domain.; [PTHR15921] PRE-MRNA CLEAVAGE COMPLEX II 122.63 0.7285 114 Mapoly0001s0565 [PTHR31949] FAMILY NOT NAMED 127.28 0.6740 115 Mapoly0072s0051 [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [KOG0597] Serine-threonine protein kinase FUSED; [GO:0006468] protein phosphorylation 128.08 0.7175 116 Mapoly0001s0238 [PF02978] Signal peptide binding domain; [GO:0048500] signal recognition particle; [PF00448] SRP54-type protein, GTPase domain; [GO:0008312] 7S RNA binding; [K03106] signal recognition particle subunit SRP54; [KOG0780] Signal recognition particle, subunit Srp54; [GO:0006614] SRP-dependent cotranslational protein targeting to membrane; [PF02881] SRP54-type protein, helical bundle domain; [GO:0005525] GTP binding; [PTHR11564:SF5] SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN; [PTHR11564] GTPASE CONTAINING FAMILY OF SIGNAL RECOGNITION PARTICLE PROTEINS 130.10 0.6542 117 Mapoly0005s0267 [PTHR23111] ZINC FINGER PROTEIN; [GO:0008270] zinc ion binding; [PF00641] Zn-finger in Ran binding protein and others 130.20 0.7080 118 Mapoly0015s0126 [GO:0008641] small protein activating enzyme activity; [GO:0005524] ATP binding; [K10685] ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19]; [KOG2013] SMT3/SUMO-activating complex, catalytic component UBA2; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [PF14732] Ubiquitin/SUMO-activating enzyme ubiquitin-like domain 130.90 0.7093 119 Mapoly0027s0186 [GO:0005524] ATP binding; [K10866] DNA repair protein RAD50 [EC:3.6.-.-]; [PF13476] AAA domain; [GO:0008270] zinc ion binding; [PF04423] Rad50 zinc hook motif; [3.6.-.-] Acting on acid anhydrides.; [GO:0006281] DNA repair; [KOG0962] DNA repair protein RAD50, ABC-type ATPase/SMC superfamily; [PTHR18867:SF12] SUBFAMILY NOT NAMED; [PTHR18867] RAD50; [GO:0004518] nuclease activity; [GO:0030870] Mre11 complex; [PF13558] Putative exonuclease SbcCD, C subunit 132.06 0.7068 120 Mapoly0119s0016 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [KOG0480] DNA replication licensing factor, MCM6 component; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630:SF43] DNA REPLICATION LICENSING FACTOR MCM6; [K02542] minichromosome maintenance protein 6; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain 133.94 0.7222 121 Mapoly0030s0009 [PF00505] HMG (high mobility group) box; [KOG0526] Nucleosome-binding factor SPN, POB3 subunit; [PF03531] Structure-specific recognition protein (SSRP1); [PTHR13711:SF39] SUBFAMILY NOT NAMED; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [PF08512] Histone chaperone Rttp106-like; [K09272] structure-specific recognition protein 1 136.43 0.7098 122 Mapoly0047s0105 [KOG4308] LRR-containing protein; [PTHR10098] RAPSYN-RELATED; [PF13516] Leucine Rich repeat; [PF13414] TPR repeat 137.53 0.7098 123 Mapoly0063s0006 [KOG2217] U4/U6.U5 snRNP associated protein; [K11984] U4/U6.U5 tri-snRNP-associated protein 1; [PTHR14152:SF5] SUBFAMILY NOT NAMED; [PTHR14152] SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES; [PF03343] SART-1 family 138.13 0.7079 124 Mapoly0031s0066 [PTHR12087:SF0] SUBFAMILY NOT NAMED; [KOG2228] Origin recognition complex, subunit 4; [PF13191] AAA ATPase domain; [PF14629] Origin recognition complex (ORC) subunit 4 C-terminus; [PTHR12087] ORIGIN RECOGNITION COMPLEX SUBUNIT 4; [K02606] origin recognition complex subunit 4 138.33 0.5767 125 Mapoly0051s0067 [PF00651] BTB/POZ domain; [PTHR24411] FAMILY NOT NAMED; [PF00917] MATH domain; [GO:0005515] protein binding; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 140.34 0.6634 126 Mapoly0042s0035 [PF01433] Peptidase family M1; [GO:0008237] metallopeptidase activity; [3.4.11.2] Membrane alanyl aminopeptidase.; [GO:0008270] zinc ion binding; [PTHR11533] PROTEASE M1 ZINC METALLOPROTEASE; [KOG1046] Puromycin-sensitive aminopeptidase and related aminopeptidases; [K01256] aminopeptidase N [EC:3.4.11.2]; [GO:0006508] proteolysis; [PF11940] Domain of unknown function (DUF3458) 141.34 0.6497 127 Mapoly0099s0053 [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 141.59 0.7003 128 Mapoly0054s0103 [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [3.6.4.13] RNA helicase.; [KOG0923] mRNA splicing factor ATP-dependent RNA helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [PF07717] Oligonucleotide/oligosaccharide-binding (OB)-fold; [K12813] pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:3.6.4.13] 141.65 0.7039 129 Mapoly0105s0060 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [K12898] heterogeneous nuclear ribonucleoprotein F/H; [KOG4211] Splicing factor hnRNP-F and related RNA-binding proteins; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED 142.02 0.7214 130 Mapoly0008s0081 [PTHR21286] NUCLEAR PORE COMPLEX PROTEIN NUP160; [K14303] nuclear pore complex protein Nup160; [KOG4521] Nuclear pore complex, Nup160 component; [PF11715] Nucleoporin Nup120/160 144.72 0.7142 131 Mapoly0042s0023 [GO:0005524] ATP binding; [2.7.12.1] Dual-specificity kinase.; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [K08866] serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]; [PTHR22974] MIXED LINEAGE PROTEIN KINASE 146.25 0.7129 132 Mapoly0074s0003 [GO:0003677] DNA binding; [PF12254] DNA polymerase alpha subunit p180 N terminal; [GO:0006260] DNA replication; [GO:0001882] nucleoside binding; [K02320] DNA polymerase alpha subunit A [EC:2.7.7.7]; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0006270] DNA replication initiation; [PF08996] DNA Polymerase alpha zinc finger; [KOG0970] DNA polymerase alpha, catalytic subunit; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT 146.33 0.6947 133 Mapoly0055s0120 - 146.36 0.6987 134 Mapoly0112s0002 [PF14750] Integrator complex subunit 2; [K13139] integrator complex subunit 2; [GO:0032039] integrator complex 146.66 0.6797 135 Mapoly0005s0208 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [KOG0244] Kinesin-like protein; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [K10395] kinesin family member 4/7/21/27; [GO:0003777] microtubule motor activity 146.76 0.7013 136 Mapoly0042s0086 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K08737] DNA mismatch repair protein MSH6; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PTHR11361:SF31] MUTS HOMOLOG 6, MSH6; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 146.89 0.7025 137 Mapoly0003s0120 [GO:0003677] DNA binding; [PTHR12708:SF0] SUBFAMILY NOT NAMED; [GO:0006260] DNA replication; [PF12213] DNA polymerases epsilon N terminal; [2.7.7.7] DNA-directed DNA polymerase.; [PTHR12708] DNA POLYMERASE EPSILON SUBUNIT B; [KOG3818] DNA polymerase epsilon, subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [GO:0003887] DNA-directed DNA polymerase activity; [K02325] DNA polymerase epsilon subunit 2 [EC:2.7.7.7] 147.34 0.6969 138 Mapoly0133s0013 [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10615] HISTONE ACETYLTRANSFERASE; [PF00856] SET domain 148.09 0.7133 139 Mapoly0001s0263 [PF08766] DEK C terminal domain; [GO:0005515] protein binding; [KOG1946] RNA polymerase I transcription factor UAF; [PF02201] SWIB/MDM2 domain; [PTHR13844] BRG-1 ASSOCIATED FACTOR 60 (BAF60) 149.19 0.6001 140 Mapoly0015s0183 [GO:0000922] spindle pole; [PF04130] Spc97 / Spc98 family; [GO:0000226] microtubule cytoskeleton organization; [GO:0005815] microtubule organizing center; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN 149.23 0.6358 141 Mapoly0023s0143 [GO:0005524] ATP binding; [PTHR23073] 26S PROTEASE REGULATORY SUBUNIT; [PTHR23073:SF18] SUBFAMILY NOT NAMED; [PF00004] ATPase family associated with various cellular activities (AAA) 150.53 0.7092 142 Mapoly0013s0062 [GO:0003677] DNA binding; [PTHR15348:SF0] SUBFAMILY NOT NAMED; [PF01388] ARID/BRIGHT DNA binding domain; [GO:0005622] intracellular; [PTHR15348] AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN (ARID DOMAIN- CONTAINING PROTEIN) (DEAD RINGER PROTEIN) (B-CELL REGULATOR OF IGH TRANSCRIPTION) (BRIGHT) 151.46 0.6997 143 Mapoly0063s0041 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR23340] ARGININE/SERINE RICH SPLICING FACTOR SF4/14; [PF01585] G-patch domain; [GO:0003676] nucleic acid binding; [PF01805] Surp module 151.49 0.6870 144 Mapoly0003s0184 [GO:0006396] RNA processing; [GO:0003677] DNA binding; [GO:0003723] RNA binding; [GO:0005524] ATP binding; [K11592] endoribonuclease Dicer [EC:3.1.26.-]; [PF02170] PAZ domain; [3.1.26.-] Endoribonucleases producing 5'-phosphomonoesters.; [PTHR14950] HELICASE-RELATED; [GO:0005515] protein binding; [GO:0016891] endoribonuclease activity, producing 5'-phosphomonoesters; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [PF03368] Dicer dimerisation domain; [PF00636] Ribonuclease III domain; [GO:0004525] ribonuclease III activity; [PF00271] Helicase conserved C-terminal domain; [PF14709] double strand RNA binding domain from DEAD END PROTEIN 1; [KOG0701] dsRNA-specific nuclease Dicer and related ribonucleases 152.26 0.6933 145 Mapoly0021s0043 - 152.81 0.6922 146 Mapoly0029s0045 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0243] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [PF12711] Kinesin motor; [GO:0003777] microtubule motor activity; [K10400] kinesin family member 15 152.87 0.6682 147 Mapoly0014s0204 [PTHR24012] FAMILY NOT NAMED; [PTHR24012:SF31] SUBFAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 153.67 0.6755 148 Mapoly0007s0066 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PTHR19306:SF1] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5 SMC5; [KOG0979] Structural maintenance of chromosome protein SMC5/Spr18, SMC superfamily; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0000724] double-strand break repair via homologous recombination 154.50 0.7055 149 Mapoly0002s0042 [GO:0031011] Ino80 complex; [PTHR13052:SF0] SUBFAMILY NOT NAMED; [PTHR13052] NFRKB-RELATED 155.43 0.6774 150 Mapoly0045s0061 [KOG1081] Transcription factor NSD1 and related SET domain proteins; [GO:0005515] protein binding; [PF00856] SET domain; [PTHR22884] SET DOMAIN PROTEINS 155.56 0.7006 151 Mapoly0005s0056 [GO:0005524] ATP binding; [PTHR11752] HELICASE SKI2W; [KOG0947] Cytoplasmic exosomal RNA helicase SKI2, DEAD-box superfamily; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF08148] DSHCT (NUC185) domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [PF13234] rRNA-processing arch domain; [GO:0003676] nucleic acid binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [K12599] antiviral helicase SKI2 [EC:3.6.4.-] 156.89 0.6867 152 Mapoly0047s0119 [KOG0891] DNA-dependent protein kinase; [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [PF08771] Rapamycin binding domain; [K07203] FKBP12-rapamycin complex-associated protein; [GO:0005515] protein binding; [GO:0008144] drug binding; [PF11865] Domain of unknown function (DUF3385); [PF00454] Phosphatidylinositol 3- and 4-kinase; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED 158.78 0.6952 153 Mapoly0001s0105 [K02541] minichromosome maintenance protein 3; [KOG0479] DNA replication licensing factor, MCM3 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11630:SF46] DNA REPLICATION LICENSING FACTOR MCM3; [PF00493] MCM2/3/5 family; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 159.72 0.7101 154 Mapoly0022s0167 [PF12717] non-SMC mitotic condensation complex subunit 1; [PF12922] non-SMC mitotic condensation complex subunit 1, N-term; [GO:0007076] mitotic chromosome condensation; [PTHR14222] CONDENSIN; [KOG0414] Chromosome condensation complex Condensin, subunit D2; [K06677] condensin complex subunit 1 160.15 0.7040 155 Mapoly0061s0132 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity; [KOG0246] Kinesin-like protein; [K10393] kinesin family member 2/24 161.21 0.6498 156 Mapoly0111s0052 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [KOG1015] Transcription regulator XNP/ATRX, DEAD-box superfamily; [K11681] helicase SWR1 [EC:3.6.4.12]; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [3.6.4.12] DNA helicase.; [PF00271] Helicase conserved C-terminal domain; [PF07529] HSA; [PF13921] Myb-like DNA-binding domain 163.90 0.7048 157 Mapoly0043s0112 [PTHR21780] UNCHARACTERIZED; [KOG4670] Uncharacterized conserved membrane protein; [PTHR21780:SF0] SUBFAMILY NOT NAMED; [PF09786] Cytochrome B561, N terminal 164.04 0.7027 158 Mapoly0005s0005 [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00856] SET domain; [PTHR22884] SET DOMAIN PROTEINS 164.10 0.6577 159 Mapoly0046s0091 [GO:0000278] mitotic cell cycle; [PTHR22870] REGULATOR OF CHROMOSOME CONDENSATION; [KOG1427] Uncharacterized conserved protein, contains RCC1 domain; [PF00415] Regulator of chromosome condensation (RCC1) repeat; [GO:0051301] cell division; [GO:0007032] endosome organization 165.11 0.6903 160 Mapoly0052s0095 [GO:0005643] nuclear pore; [PTHR31344:SF0] SUBFAMILY NOT NAMED; [K14310] nuclear pore complex protein Nup205; [PF11894] Protein of unknown function (DUF3414); [PTHR31344] FAMILY NOT NAMED; [KOG1835] Uncharacterized conserved protein 166.49 0.6816 161 Mapoly0010s0012 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF06461] Domain of Unknown Function (DUF1086); [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00176] SNF2 family N-terminal domain; [PF06465] Domain of Unknown Function (DUF1087); [3.6.4.12] DNA helicase.; [PF00271] Helicase conserved C-terminal domain; [K11643] chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12]; [KOG0384] Chromodomain-helicase DNA-binding protein 166.73 0.7094 162 Mapoly0005s0051 [GO:0003723] RNA binding; [GO:0000339] RNA cap binding; [GO:0045292] mRNA cis splicing, via spliceosome; [GO:0051028] mRNA transport; [PF02854] MIF4G domain; [GO:0005515] protein binding; [KOG1104] Nuclear cap-binding complex, subunit NCBP1/CBP80; [K12882] nuclear cap-binding protein subunit 1; [GO:0016070] RNA metabolic process; [PTHR12412] CAP BINDING PROTEIN; [GO:0005846] nuclear cap binding complex; [PF09090] MIF4G like; [PF09088] MIF4G like 166.96 0.7093 163 Mapoly0084s0045 [PF07719] Tetratricopeptide repeat; [KOG1211] Amidases; [PF13414] TPR repeat; [PTHR11895] AMIDASE; [GO:0016884] carbon-nitrogen ligase activity, with glutamine as amido-N-donor; [PTHR11895:SF6] AMIDASE; [PF01425] Amidase 167.43 0.6533 164 Mapoly0098s0043 [PF12717] non-SMC mitotic condensation complex subunit 1; [GO:0007076] mitotic chromosome condensation; [K11491] condensin-2 complex subunit D3; [PTHR14222:SF1] CONDENSIN; [PTHR14222] CONDENSIN 167.57 0.7024 165 Mapoly0002s0004 [KOG1189] Global transcriptional regulator, cell division control protein; [PF00557] Metallopeptidase family M24; [PF08512] Histone chaperone Rttp106-like; [PTHR13980] CDC68 RELATED; [PF08644] FACT complex subunit (SPT16/CDC68) 167.84 0.6614 166 Mapoly0084s0051 [2.1.1.43] Histone-lysine N-methyltransferase.; [GO:0005515] protein binding; [PF00856] SET domain; [KOG1079] Transcriptional repressor EZH1; [PTHR22884] SET DOMAIN PROTEINS; [K11430] enhancer of zeste [EC:2.1.1.43] 168.58 0.6583 167 Mapoly0006s0287 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02209] minichromosome maintenance protein 5 (cell division control protein 46); [PTHR11630:SF42] DNA REPLICATION LICENSING FACTOR MCM5; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain; [KOG0481] DNA replication licensing factor, MCM5 component 169.08 0.7040 168 Mapoly0081s0071 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [PF00628] PHD-finger; [GO:0005515] protein binding; [PF12738] twin BRCT domain; [GO:0046872] metal ion binding 169.61 0.6969 169 Mapoly0087s0021 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [KOG0969] DNA polymerase delta, catalytic subunit; [PTHR10322:SF11] DNA POLYMERASE DELTA CATALYTIC SUBUNIT; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [K02327] DNA polymerase delta subunit 1 [EC:2.7.7.7]; [PF14260] C4-type zinc-finger of DNA polymerase delta; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT 170.58 0.6777 170 Mapoly0005s0161 [GO:0003677] DNA binding; [PTHR13451:SF0] SUBFAMILY NOT NAMED; [3.1.22.-] Endodeoxyribonucleases producing other than 5'-phosphomonoesters.; [K08991] crossover junction endonuclease MUS81 [EC:3.1.22.-]; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PF02732] ERCC4 domain 170.71 0.6640 171 Mapoly0014s0115 [PTHR15137] TRANSCRIPTION INITIATION FACTOR TFIID; [PF01433] Peptidase family M1; [GO:0008237] metallopeptidase activity; [GO:0008270] zinc ion binding; [K03128] transcription initiation factor TFIID subunit 2; [KOG1932] TATA binding protein associated factor 171.46 0.6552 172 Mapoly0042s0049 - 171.76 0.7024 173 Mapoly0074s0025 [PTHR12933] ORF PROTEIN-RELATED; [PF06862] Protein of unknown function (DUF1253); [KOG2340] Uncharacterized conserved protein; [GO:0005634] nucleus 173.49 0.5819 174 Mapoly0043s0047 [GO:0005515] protein binding; [PF00612] IQ calmodulin-binding motif; [PTHR25069] FAMILY NOT NAMED; [PF00307] Calponin homology (CH) domain 174.93 0.6936 175 Mapoly0016s0083 [PF12214] Cell cycle regulated microtubule associated protein; [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [PTHR14326:SF9] TARGETING PROTEIN FOR XKLP2; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2) 176.35 0.6914 176 Mapoly0119s0035 - 177.32 0.6605 177 Mapoly0135s0035 [GO:0003676] nucleic acid binding; [PF02037] SAP domain 179.53 0.6793 178 Mapoly0116s0028 [PTHR23074:SF19] KATANIN-RELATED; [GO:0005524] ATP binding; [3.6.4.3] Microtubule-severing ATPase.; [K07767] microtubule-severing ATPase [EC:3.6.4.3]; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0738] AAA+-type ATPase; [PTHR23074] AAA ATPASE; [PF09336] Vps4 C terminal oligomerisation domain 179.72 0.6651 179 Mapoly0004s0300 [GO:0005524] ATP binding; [PTHR11909:SF7] CELL DIVISION CONTROL PROTEIN 7; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K02214] cell division control protein 7 [EC:2.7.11.1]; [KOG1167] Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination; [GO:0006468] protein phosphorylation; [PTHR11909] CASEIN KINASE-RELATED 179.81 0.7005 180 Mapoly0112s0032 [KOG2652] RNA polymerase II transcription initiation factor TFIIA, large chain; [PTHR12694] TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; [PTHR12694:SF8] TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; [PF03153] Transcription factor IIA, alpha/beta subunit; [GO:0005672] transcription factor TFIIA complex; [K03122] transcription initiation factor TFIIA large subunit; [GO:0006367] transcription initiation from RNA polymerase II promoter 181.50 0.6444 181 Mapoly0014s0195 [PTHR10641:SF17] CELL DIVISION CYCLE 5-LIKE PROTEIN; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [PF13921] Myb-like DNA-binding domain; [PF11831] pre-mRNA splicing factor component; [K12860] pre-mRNA-splicing factor CDC5/CEF1 183.99 0.6802 182 Mapoly0013s0011 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 184.67 0.6885 183 Mapoly0031s0115 [PF00569] Zinc finger, ZZ type; [GO:0008270] zinc ion binding; [KOG1776] Zn-binding protein Push; [PF13764] E3 ubiquitin-protein ligase UBR4; [PF02207] Putative zinc finger in N-recognin (UBR box); [6.3.2.19] Ubiquitin--protein ligase.; [K10691] E3 ubiquitin-protein ligase UBR4 [EC:6.3.2.19]; [GO:0004842] ubiquitin-protein ligase activity; [PTHR21725:SF1] gb def: Hypothetical protein C44E4.7; [PTHR21725] PUSHOVER/RETINOBLASTOMA-ASSOCIATED FACTOR 600 184.76 0.6053 184 Mapoly0005s0256 [PF12220] U1 small nuclear ribonucleoprotein of 70kDa MW N terminal; [KOG0113] U1 small nuclear ribonucleoprotein (RRM superfamily); [PTHR13952:SF5] PREDICTED: HYPOTHETICAL PROTEIN, PARTIAL; [PTHR13952] U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD; [K11093] U1 small nuclear ribonucleoprotein 70kDa; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 184.90 0.6698 185 Mapoly0183s0015 [GO:0016020] membrane; [PTHR12741] LYST-INTERACTING PROTEIN LIP5 (DOPAMINE RESPONSIVE PROTEIN DRG-1); [PF02364] 1,3-beta-glucan synthase component; [PF04652] Vta1 like; [GO:0006075] (1-3)-beta-D-glucan biosynthetic process; [KOG0916] 1,3-beta-glucan synthase/callose synthase catalytic subunit; [GO:0000148] 1,3-beta-D-glucan synthase complex; [PF14288] 1,3-beta-glucan synthase subunit FKS1, domain-1; [K11000] callose synthase [EC:2.4.1.-]; [PTHR12741:SF6] SUBFAMILY NOT NAMED; [GO:0003843] 1,3-beta-D-glucan synthase activity; [2.4.1.-] Hexosyltransferases. 185.47 0.6323 186 Mapoly0001s0065 [GO:0019867] outer membrane; [PF07244] Surface antigen variable number repeat; [PF01103] Surface antigen; [PTHR12815] SORTING AND ASSEMBLY MACHINERY (SAM50) PROTEIN 187.58 0.6434 187 Mapoly0005s0130 [GO:0042393] histone binding; [PF02182] SAD/SRA domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF13923] Zinc finger, C3HC4 type (RING finger); [PTHR14140] E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED 188.02 0.6707 188 Mapoly0154s0005 [PTHR22852] LETHAL(2)DENTICLELESS PROTEIN (RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN); [KOG0265] U5 snRNP-specific protein-like factor and related proteins; [K11790] denticleless; [GO:0005515] protein binding; [PF00400] WD domain, G-beta repeat 188.79 0.6937 189 Mapoly0095s0046 [PF13919] Asx homology domain; [GO:0006355] regulation of transcription, DNA-dependent; [PTHR10071] TRANSCRIPTION FACTOR GATA (GATA BINDING FACTOR); [GO:0043565] sequence-specific DNA binding; [GO:0008270] zinc ion binding; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF00320] GATA zinc finger 190.90 0.6322 190 Mapoly0112s0022 [PTHR19932] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; [GO:0005515] protein binding; [KOG1274] WD40 repeat protein; [K11274] chromosome transmission fidelity protein 4; [PTHR19932:SF10] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN 1; [PF00400] WD domain, G-beta repeat; [PF12341] Protein of unknown function (DUF3639) 191.61 0.6935 191 Mapoly0029s0152 [PTHR15239] UNCHARACTERIZED; [PF05833] Fibronectin-binding protein A N-terminus (FbpA); [PTHR15239:SF1] COLON CANCER ANTIGEN 1; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding; [PF11923] Domain of unknown function (DUF3441); [KOG2030] Predicted RNA-binding protein; [PF05670] Domain of unknown function (DUF814) 193.10 0.6574 192 Mapoly0101s0048 [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat 195.03 0.6907 193 Mapoly0103s0079 [GO:0003677] DNA binding; [PTHR13763:SF0] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0005634] nucleus; [GO:0006281] DNA repair; [GO:0004842] ubiquitin-protein ligase activity; [KOG4362] Transcriptional regulator BRCA1; [PTHR13763] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; [PF13771] PHD-like zinc-binding domain 195.08 0.6945 194 Mapoly0080s0001 [GO:0005515] protein binding; [PTHR15271] CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; [KOG1009] Chromatin assembly complex 1 subunit B/CAC2 (contains WD40 repeats); [K10751] chromatin assembly factor 1 subunit B; [PF00400] WD domain, G-beta repeat 195.41 0.6876 195 Mapoly0004s0058 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PTHR13215:SF4] SUBFAMILY NOT NAMED; [PF08766] DEK C terminal domain; [PF02229] Transcriptional Coactivator p15 (PC4); [KOG2712] Transcriptional coactivator; [PTHR13215] RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; [GO:0003713] transcription coactivator activity 196.10 0.6555 196 Mapoly0064s0110 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR13394] ORIGIN RECOGNITION COMPLEX SUBUNIT 6; [PF05460] Origin recognition complex subunit 6 (ORC6); [GO:0005664] nuclear origin of replication recognition complex; [K02608] origin recognition complex subunit 6; [PTHR13394:SF0] SUBFAMILY NOT NAMED; [KOG4557] Origin recognition complex, subunit 6 196.21 0.6918 197 Mapoly0043s0064 [PF10979] Protein of unknown function (DUF2786) 197.63 0.6917 198 Mapoly0117s0005 [K13109] IK cytokine; [PTHR12765] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [KOG2498] IK cytokine down-regulator of HLA class II; [PF07807] RED-like protein C-terminal region; [PTHR12765:SF5] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [GO:0005634] nucleus; [PF07808] RED-like protein N-terminal region 197.80 0.6774 199 Mapoly0078s0012 [GO:0006396] RNA processing; [PTHR11061] RNA M5U METHYLTRANSFERASE FAMILY; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0008173] RNA methyltransferase activity; [PF05958] tRNA (Uracil-5-)-methyltransferase; [GO:0046872] metal ion binding; [KOG2187] tRNA uracil-5-methyltransferase and related tRNA-modifying enzymes 198.04 0.6679 200 Mapoly0081s0047 [PF00773] RNB domain; [PF13638] PIN domain; [3.1.13.-] Exoribonucleases producing 5'-phosphomonoesters.; [K12585] exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]; [PTHR23355] RIBONUCLEASE; [KOG2102] Exosomal 3'-5' exoribonuclease complex, subunit Rrp44/Dis3 198.70 0.6666