Guide Gene
- Gene ID
- Mapoly0026s0077
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [2.7.11.1] Non-specific serine/threonine protein kinase.; [PF08064] UME (NUC010) domain; [PF00454] Phosphatidylinositol 3- and 4-kinase; [K06640] ataxia telangiectasia and Rad3 related [EC:2.7.11.1]; [GO:0004674] protein serine/threonine kinase activity; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [KOG0890] Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0026s0077 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [2.7.11.1] Non-specific serine/threonine protein kinase.; [PF08064] UME (NUC010) domain; [PF00454] Phosphatidylinositol 3- and 4-kinase; [K06640] ataxia telangiectasia and Rad3 related [EC:2.7.11.1]; [GO:0004674] protein serine/threonine kinase activity; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [KOG0890] Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination 0.00 1.0000 1 Mapoly0001s0406 [GO:0000922] spindle pole; [KOG2000] Gamma-tubulin complex, DGRIP91/SPC98 component; [PF04130] Spc97 / Spc98 family; [GO:0005856] cytoskeleton; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [GO:0007020] microtubule nucleation; [PTHR19302:SF14] GAMMA-TUBULIN COMPLEX COMPONENT 3 (GCP-3) 1.41 0.8309 2 Mapoly0006s0290 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR10670:SF0] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A; [GO:0000166] nucleotide binding; [GO:0008270] zinc ion binding; [2.7.7.7] DNA-directed DNA polymerase.; [KOG1798] DNA polymerase epsilon, catalytic subunit A; [PF08490] Domain of unknown function (DUF1744); [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF00136] DNA polymerase family B; [GO:0008622] epsilon DNA polymerase complex; [K02324] DNA polymerase epsilon subunit 1 [EC:2.7.7.7]; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10670] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A 5.92 0.8429 3 Mapoly0008s0250 [PTHR24007] BRCA1-ASSOCIATED PROTEIN; [PF00917] MATH domain; [GO:0005515] protein binding; [GO:0006281] DNA repair; [PF14631] Fanconi anaemia protein FancD2 nuclease; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 6.71 0.8207 4 Mapoly0061s0085 [PF14868] Domain of unknown function (DUF4487) 9.59 0.8249 5 Mapoly0008s0081 [PTHR21286] NUCLEAR PORE COMPLEX PROTEIN NUP160; [K14303] nuclear pore complex protein Nup160; [KOG4521] Nuclear pore complex, Nup160 component; [PF11715] Nucleoporin Nup120/160 12.49 0.8184 6 Mapoly0002s0004 [KOG1189] Global transcriptional regulator, cell division control protein; [PF00557] Metallopeptidase family M24; [PF08512] Histone chaperone Rttp106-like; [PTHR13980] CDC68 RELATED; [PF08644] FACT complex subunit (SPT16/CDC68) 13.19 0.7796 7 Mapoly0033s0057 [2.3.1.-] Transferring groups other than amino-acyl groups.; [PTHR11076:SF1] ESTABLISHMENT OF COHESION 1 (ECO1) HOMOLOG; [PF13880] ESCO1/2 acetyl-transferase; [PF13878] zinc-finger of acetyl-transferase ESCO; [KOG3014] Protein involved in establishing cohesion between sister chromatids during DNA replication; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [K11268] N-acetyltransferase [EC:2.3.1.-] 14.39 0.8295 8 Mapoly0029s0003 [KOG1824] TATA-binding protein-interacting protein; [PTHR12696] TIP120; [PF08623] TATA-binding protein interacting (TIP20); [PF13646] HEAT repeats 15.59 0.8043 9 Mapoly0043s0081 [GO:0005524] ATP binding; [PF02889] Sec63 Brl domain; [PTHR11752] HELICASE SKI2W; [3.6.4.13] RNA helicase.; [PF00270] DEAD/DEAH box helicase; [PTHR11752:SF7] U520; [PF00271] Helicase conserved C-terminal domain; [KOG0951] RNA helicase BRR2, DEAD-box superfamily; [GO:0003676] nucleic acid binding; [K12854] pre-mRNA-splicing helicase BRR2 [EC:3.6.4.13] 16.25 0.7998 10 Mapoly0125s0035 [PTHR23081] RNA POLYMERASE II CTD PHOSPHATASE; [PF00035] Double-stranded RNA binding motif; [PF03031] NLI interacting factor-like phosphatase; [GO:0005515] protein binding; [PTHR23081:SF1] RNA POLYMERASE II CTD PHOSPHATASE 18.89 0.7882 11 Mapoly0004s0169 [GO:0003677] DNA binding; [GO:0006338] chromatin remodeling; [GO:0005524] ATP binding; [PF09110] HAND; [K11654] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]; [GO:0043044] ATP-dependent chromatin remodeling; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [GO:0005634] nucleus; [PTHR10799:SF73] ISWI CHROMATIN-REMODELING COMPLEX ATPASE ISW1; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [KOG0385] Chromatin remodeling complex WSTF-ISWI, small subunit; [GO:0003676] nucleic acid binding; [GO:0031491] nucleosome binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [PF09111] SLIDE 18.97 0.8119 12 Mapoly0042s0082 [GO:0005643] nuclear pore; [PF07926] TPR/MLP1/MLP2-like protein; [PTHR18898] NUCLEOPROTEIN TPR-RELATED; [K09291] nucleoprotein TPR; [KOG4674] Uncharacterized conserved coiled-coil protein; [GO:0006606] protein import into nucleus 19.44 0.8140 13 Mapoly0007s0100 [PTHR15828] CYTOKINE RECEPTOR-LIKE FACTOR 3 19.80 0.7989 14 Mapoly0039s0120 [KOG1805] DNA replication helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PTHR10887:SF14] DNA2-LIKE HELICASE; [3.6.4.12] DNA helicase.; [PF13086] AAA domain; [GO:0033567] DNA replication, Okazaki fragment processing; [PF01930] Domain of unknown function DUF83; [GO:0017108] 5'-flap endonuclease activity; [GO:0043142] single-stranded DNA-dependent ATPase activity; [PF13087] AAA domain; [PF08696] DNA replication factor Dna2; [K10742] DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12] 20.49 0.7834 15 Mapoly0138s0046 [KOG1803] DNA helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PF13086] AAA domain; [PF13087] AAA domain 20.86 0.7980 16 Mapoly0162s0013 [PF00929] Exonuclease; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [PTHR11361:SF34] DNA MISMATCH REPAIR PROTEIN MUTS; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [KOG0218] Mismatch repair MSH3; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 20.98 0.8039 17 Mapoly0043s0050 [PTHR23019:SF0] SUBFAMILY NOT NAMED; [K14314] nuclear pore complex protein Nup210; [PF02368] Bacterial Ig-like domain (group 2); [PTHR23019] NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED; [KOG1833] Nuclear pore complex, gp210 component 22.49 0.7868 18 Mapoly0001s0208 [PTHR31431] FAMILY NOT NAMED; [KOG4833] Uncharacterized conserved protein; [K14311] nuclear pore complex protein Nup188; [PF10487] Nucleoporin subcomplex protein binding to Pom34 26.15 0.7916 19 Mapoly0097s0045 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11752] HELICASE SKI2W; [2.7.7.7] DNA-directed DNA polymerase.; [K02349] DNA polymerase theta subunit [EC:2.7.7.7]; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF00476] DNA polymerase family A; [GO:0003676] nucleic acid binding; [GO:0003887] DNA-directed DNA polymerase activity; [KOG0950] DNA polymerase theta/eta, DEAD-box superfamily 28.57 0.7704 20 Mapoly0001s0472 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED 29.51 0.7989 21 Mapoly0044s0125 [PTHR22880] FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF02791] DDT domain 29.66 0.8010 22 Mapoly0024s0107 [PF07719] Tetratricopeptide repeat; [GO:0005515] protein binding; [PF13414] TPR repeat; [K03350] anaphase-promoting complex subunit 3; [KOG1126] DNA-binding cell division cycle control protein; [PF13181] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat; [PTHR12558] CELL DIVISION CYCLE 16,23,27; [PTHR12558:SF11] CELL DIVISION CYCLE 27; [PF12895] Anaphase-promoting complex, cyclosome, subunit 3 29.88 0.7613 23 Mapoly0001s0044 [PTHR31110] FAMILY NOT NAMED 31.18 0.7922 24 Mapoly0125s0021 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR23273:SF0] SUBFAMILY NOT NAMED; [GO:0008270] zinc ion binding; [PF04057] Replication factor-A protein 1, N-terminal domain; [PF00098] Zinc knuckle; [GO:0005634] nucleus; [PF08646] Replication factor-A C terminal domain; [GO:0003676] nucleic acid binding; [K07466] replication factor A1; [PTHR23273] REPLICATION FACTOR A 1, RFA1; [PF01336] OB-fold nucleic acid binding domain 32.25 0.7412 25 Mapoly0044s0071 [PTHR12827] MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; [PF12859] Anaphase-promoting complex subunit 1; [K03348] anaphase-promoting complex subunit 1; [KOG1858] Anaphase-promoting complex (APC), subunit 1 (meiotic check point regulator/Tsg24); [GO:0005680] anaphase-promoting complex 33.20 0.7657 26 Mapoly0070s0053 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF09382] RQC domain; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [K10901] bloom syndrome protein [EC:3.6.4.12]; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 35.78 0.7883 27 Mapoly0119s0035 - 36.03 0.7542 28 Mapoly0045s0096 [K08775] breast cancer 2 susceptibility protein; [PTHR11289] BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2; [GO:0003697] single-stranded DNA binding; [PF09169] BRCA2, helical; [PTHR11289:SF0] SUBFAMILY NOT NAMED; [GO:0006281] DNA repair; [PF09103] BRCA2, oligonucleotide/oligosaccharide-binding, domain 1; [GO:0000724] double-strand break repair via homologous recombination; [GO:0006310] DNA recombination 37.15 0.7204 29 Mapoly0036s0123 [GO:0000922] spindle pole; [PTHR19302:SF13] GAMMA-TUBULIN COMPLEX COMPONENT 2 (GCP-2); [PF04130] Spc97 / Spc98 family; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [KOG2001] Gamma-tubulin complex, DGRIP84/SPC97 component 38.37 0.7969 30 Mapoly0056s0030 [KOG1040] Polyadenylation factor I complex, subunit, Yth1 (CPSF subunit); [PTHR12357] YTH (YT521-B HOMOLOGY) DOMAIN-CONTAINING; [PF04146] YT521-B-like domain; [PTHR12357:SF3] SPLICING FACTOR YT521-B 38.74 0.7417 31 Mapoly0042s0023 [GO:0005524] ATP binding; [2.7.12.1] Dual-specificity kinase.; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [K08866] serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]; [PTHR22974] MIXED LINEAGE PROTEIN KINASE 39.55 0.7965 32 Mapoly0037s0093 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG4280] Kinesin-like protein; [PTHR24115:SF87] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [PF12711] Kinesin motor; [GO:0003777] microtubule motor activity 41.82 0.7706 33 Mapoly0021s0007 [PTHR11851:SF85] AGR251CP; [3.4.24.56] Insulysin.; [KOG0959] N-arginine dibasic convertase NRD1 and related Zn2+-dependent endopeptidases, insulinase superfamily; [K01408] insulysin [EC:3.4.24.56]; [PTHR11851] METALLOPROTEASE; [PF05193] Peptidase M16 inactive domain; [PF00675] Insulinase (Peptidase family M16) 44.94 0.7241 34 Mapoly0042s0049 - 45.30 0.7836 35 Mapoly0026s0003 [GO:0003723] RNA binding; [GO:0005524] ATP binding; [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [K12818] ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13]; [3.6.4.13] RNA helicase.; [PF00575] S1 RNA binding domain; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [GO:0003676] nucleic acid binding; [KOG0922] DEAH-box RNA helicase; [PF07717] Oligonucleotide/oligosaccharide-binding (OB)-fold 45.83 0.7796 36 Mapoly0082s0057 [PTHR32282] FAMILY NOT NAMED; [PF00912] Transglycosylase; [PTHR32282:SF0] SUBFAMILY NOT NAMED; [PF00905] Penicillin binding protein transpeptidase domain; [GO:0008658] penicillin binding 45.92 0.7211 37 Mapoly0135s0025 [PF13513] HEAT-like repeat; [GO:0005515] protein binding; [PTHR23346] TRANSLATIONAL ACTIVATOR GCN1-RELATED; [PF02985] HEAT repeat; [PTHR23346:SF7] TRANSLATIONAL ACTIVATOR GCN1-RELATED; [PF12074] Domain of unknown function (DUF3554); [KOG1242] Protein containing adaptin N-terminal region; [PF13646] HEAT repeats 47.33 0.7507 38 Mapoly0013s0109 [PF00514] Armadillo/beta-catenin-like repeat; [PF00651] BTB/POZ domain; [GO:0005515] protein binding; [KOG0166] Karyopherin (importin) alpha; [PTHR23315] BETA CATENIN-RELATED ARMADILLO REPEAT-CONTAINING 47.37 0.7587 39 Mapoly0010s0026 [GO:0006357] regulation of transcription from RNA polymerase II promoter; [PTHR13114] TRANSCRIPTIONAL CO-ACTIVATOR CRSP77-RELATED; [PF10156] Subunit 17 of Mediator complex; [GO:0001104] RNA polymerase II transcription cofactor activity; [GO:0016592] mediator complex 47.62 0.6978 40 Mapoly0111s0052 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [KOG1015] Transcription regulator XNP/ATRX, DEAD-box superfamily; [K11681] helicase SWR1 [EC:3.6.4.12]; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [3.6.4.12] DNA helicase.; [PF00271] Helicase conserved C-terminal domain; [PF07529] HSA; [PF13921] Myb-like DNA-binding domain 49.48 0.7863 41 Mapoly0064s0056 [GO:0003677] DNA binding; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF01429] Methyl-CpG binding domain; [GO:0005634] nucleus; [PF15612] WSTF, HB1, Itc1p, MBD9 motif 1; [PTHR14140] E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED 51.48 0.7857 42 Mapoly0091s0014 [PTHR12596:SF1] GB DEF: T27C4.14 PROTEIN; [PTHR12596] EXPORTIN 4,7-RELATED; [KOG4541] Nuclear transport receptor exportin 4 (importin beta superfamily) 51.48 0.7593 43 Mapoly0054s0064 [PF03178] CPSF A subunit region; [PF10433] Mono-functional DNA-alkylating methyl methanesulfonate N-term; [PTHR10644:SF3] DNA DAMAGE-BINDING PROTEIN 1 (DAMAGE-SPECIFIC DNA-BINDING PROTEIN 1)(UV-DAMAGED DNA-BINDING FACTOR); [K10610] DNA damage-binding protein 1; [GO:0005634] nucleus; [PTHR10644] DNA REPAIR/RNA PROCESSING CPSF FAMILY; [KOG1897] Damage-specific DNA binding complex, subunit DDB1; [GO:0003676] nucleic acid binding 51.79 0.7024 44 Mapoly0005s0127 - 52.68 0.7658 45 Mapoly0122s0062 [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 53.72 0.7846 46 Mapoly0119s0054 [GO:0008641] small protein activating enzyme activity; [GO:0005524] ATP binding; [PF09358] Ubiquitin-activating enzyme e1 C-terminal domain; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [PTHR10953:SF4] UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 1 (UBIQUITIN-ACTIVATING ENZYME E1) 54.99 0.7644 47 Mapoly0011s0202 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain 56.48 0.7871 48 Mapoly0001s0391 [GO:0005634] nucleus; [PF05965] F/Y rich C-terminus 57.27 0.7654 49 Mapoly0058s0047 [PF00091] Tubulin/FtsZ family, GTPase domain; [PTHR23084] PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED; [PF02493] MORN repeat 58.02 0.6467 50 Mapoly0023s0143 [GO:0005524] ATP binding; [PTHR23073] 26S PROTEASE REGULATORY SUBUNIT; [PTHR23073:SF18] SUBFAMILY NOT NAMED; [PF00004] ATPase family associated with various cellular activities (AAA) 60.41 0.7649 51 Mapoly0063s0006 [KOG2217] U4/U6.U5 snRNP associated protein; [K11984] U4/U6.U5 tri-snRNP-associated protein 1; [PTHR14152:SF5] SUBFAMILY NOT NAMED; [PTHR14152] SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES; [PF03343] SART-1 family 60.43 0.7622 52 Mapoly0006s0069 - 60.60 0.7465 53 Mapoly0030s0101 [GO:0042393] histone binding; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [K11647] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-]; [KOG0386] Chromatin remodeling complex SWI/SNF, component SWI2 and related ATPases (DNA/RNA helicase superfamily); [PTHR10799:SF209] GLOBAL TRANSCRIPTION ACTIVATOR SNF2L2 (ATP-DEPENDENT HELICASE SMARCA2); [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [PF14619] Snf2-ATP coupling, chromatin remodelling complex 61.51 0.7656 54 Mapoly0029s0052 [GO:0006357] regulation of transcription from RNA polymerase II promoter; [PTHR12950] FAMILY NOT NAMED; [GO:0001104] RNA polymerase II transcription cofactor activity; [GO:0016592] mediator complex; [PF06333] Mediator complex subunit 13 C-terminal 63.98 0.7615 55 Mapoly0118s0005 [GO:0008233] peptidase activity; [3.4.22.49] Separase.; [K02365] separase [EC:3.4.22.49]; [GO:0005634] nucleus; [PF03568] Peptidase family C50; [GO:0006508] proteolysis; [PTHR12792] EXTRA SPINDLE POLES 1-RELATED 64.00 0.7713 56 Mapoly0131s0010 [PTHR15921:SF3] SUBFAMILY NOT NAMED; [KOG2071] mRNA cleavage and polyadenylation factor I/II complex, subunit Pcf11; [PF04818] RNA polymerase II-binding domain.; [PTHR15921] PRE-MRNA CLEAVAGE COMPLEX II 64.81 0.7678 57 Mapoly0015s0089 [GO:0005524] ATP binding; [KOG0335] ATP-dependent RNA helicase; [3.6.4.13] RNA helicase.; [K11594] ATP-dependent RNA helicase [EC:3.6.4.13]; [PF00270] DEAD/DEAH box helicase; [PTHR24031:SF9] HELICASE CONSERVED C-TERMINAL DOMAIN, PUTATIVE; [PF00271] Helicase conserved C-terminal domain; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding 66.11 0.7273 58 Mapoly0033s0098 [PTHR16047] RFWD3 PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PTHR16047:SF7] RFWD3 PROTEIN-RELATED; [KOG1645] RING-finger-containing E3 ubiquitin ligase 68.18 0.7556 59 Mapoly0102s0001 [K06228] fused [EC:2.7.11.1]; [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR22983:SF6] MAPK KINASE 2-RELATED; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [KOG0598] Ribosomal protein S6 kinase and related proteins; [PF13646] HEAT repeats 68.67 0.7678 60 Mapoly0045s0076 - 70.31 0.6797 61 Mapoly0076s0066 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0008026] ATP-dependent helicase activity; [K11136] regulator of telomere elongation helicase 1; [PF13307] Helicase C-terminal domain; [PF06733] DEAD_2; [PTHR11472] DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; [GO:0006139] nucleobase-containing compound metabolic process; [GO:0004003] ATP-dependent DNA helicase activity; [GO:0003676] nucleic acid binding; [PTHR11472:SF4] REGULATOR OF TELOMERE ELONGATION HELICASE 1 RTEL1; [KOG1132] Helicase of the DEAD superfamily; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 70.38 0.7140 62 Mapoly0209s0008 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF67] DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 70.43 0.7775 63 Mapoly0117s0005 [K13109] IK cytokine; [PTHR12765] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [KOG2498] IK cytokine down-regulator of HLA class II; [PF07807] RED-like protein C-terminal region; [PTHR12765:SF5] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [GO:0005634] nucleus; [PF07808] RED-like protein N-terminal region 70.94 0.7458 64 Mapoly0047s0119 [KOG0891] DNA-dependent protein kinase; [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [PF08771] Rapamycin binding domain; [K07203] FKBP12-rapamycin complex-associated protein; [GO:0005515] protein binding; [GO:0008144] drug binding; [PF11865] Domain of unknown function (DUF3385); [PF00454] Phosphatidylinositol 3- and 4-kinase; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED 72.07 0.7574 65 Mapoly0030s0009 [PF00505] HMG (high mobility group) box; [KOG0526] Nucleosome-binding factor SPN, POB3 subunit; [PF03531] Structure-specific recognition protein (SSRP1); [PTHR13711:SF39] SUBFAMILY NOT NAMED; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [PF08512] Histone chaperone Rttp106-like; [K09272] structure-specific recognition protein 1 72.25 0.7521 66 Mapoly0004s0250 [GO:0005643] nuclear pore; [PF07817] GLE1-like protein; [GO:0016973] poly(A)+ mRNA export from nucleus; [KOG2412] Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor; [PTHR12960:SF0] SUBFAMILY NOT NAMED; [PTHR12960] GLE-1-RELATED 75.76 0.7486 67 Mapoly0031s0090 [KOG0379] Kelch repeat-containing proteins; [PF13418] Galactose oxidase, central domain; [PTHR23244] KELCH REPEAT DOMAIN; [PF13415] Galactose oxidase, central domain 76.66 0.7586 68 Mapoly0022s0121 - 77.65 0.7618 69 Mapoly0047s0105 [KOG4308] LRR-containing protein; [PTHR10098] RAPSYN-RELATED; [PF13516] Leucine Rich repeat; [PF13414] TPR repeat 78.84 0.7563 70 Mapoly0004s0202 - 79.18 0.7549 71 Mapoly0005s0051 [GO:0003723] RNA binding; [GO:0000339] RNA cap binding; [GO:0045292] mRNA cis splicing, via spliceosome; [GO:0051028] mRNA transport; [PF02854] MIF4G domain; [GO:0005515] protein binding; [KOG1104] Nuclear cap-binding complex, subunit NCBP1/CBP80; [K12882] nuclear cap-binding protein subunit 1; [GO:0016070] RNA metabolic process; [PTHR12412] CAP BINDING PROTEIN; [GO:0005846] nuclear cap binding complex; [PF09090] MIF4G like; [PF09088] MIF4G like 79.20 0.7606 72 Mapoly0035s0057 [PF03109] ABC1 family; [PTHR10566] CHAPERONE-ACTIVITY OF BC1 COMPLEX (CABC1)-RELATED; [KOG1235] Predicted unusual protein kinase; [K08869] aarF domain-containing kinase 79.30 0.6226 73 Mapoly0039s0001 - 79.37 0.7313 74 Mapoly0080s0001 [GO:0005515] protein binding; [PTHR15271] CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; [KOG1009] Chromatin assembly complex 1 subunit B/CAC2 (contains WD40 repeats); [K10751] chromatin assembly factor 1 subunit B; [PF00400] WD domain, G-beta repeat 80.31 0.7630 75 Mapoly0013s0201 [PTHR23269:SF0] SUBFAMILY NOT NAMED; [KOG0128] RNA-binding protein SART3 (RRM superfamily); [PF05391] Lsm interaction motif; [GO:0003676] nucleic acid binding; [PTHR23269] RIBONUCLEOPROTEIN-RELATED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 80.42 0.7494 76 Mapoly0073s0063 [GO:0016020] membrane; [GO:0005524] ATP binding; [GO:0017038] protein import; [PF07516] SecA Wing and Scaffold domain; [PTHR30612] SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM; [PF07517] SecA DEAD-like domain; [PF01043] SecA preprotein cross-linking domain; [K03070] preprotein translocase subunit SecA 80.99 0.6398 77 Mapoly0130s0046 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF14493] Helix-turn-helix domain; [PF09382] RQC domain; [K10900] werner syndrome ATP-dependent helicase [EC:3.6.4.12]; [KOG0353] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 84.17 0.7507 78 Mapoly0101s0062 [GO:0003677] DNA binding; [PTHR20856:SF7] DNA-DIRECTED RNA POLYMERASE II SUBUNIT 2; [KOG0214] RNA polymerase II, second largest subunit; [PF04567] RNA polymerase Rpb2, domain 5; [K03010] DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]; [PF04565] RNA polymerase Rpb2, domain 3; [PTHR20856] DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2; [PF00562] RNA polymerase Rpb2, domain 6; [PF04566] RNA polymerase Rpb2, domain 4; [GO:0032549] ribonucleoside binding; [PF04561] RNA polymerase Rpb2, domain 2; [GO:0006351] transcription, DNA-dependent; [GO:0003899] DNA-directed RNA polymerase activity; [2.7.7.6] DNA-directed RNA polymerase.; [PF04560] RNA polymerase Rpb2, domain 7; [PF04563] RNA polymerase beta subunit 84.80 0.7064 79 Mapoly0043s0044 [PTHR13257:SF0] SUBFAMILY NOT NAMED; [K14318] nuclear pore complex protein Nup88; [PF10168] Nuclear pore component; [KOG4460] Nuclear pore complex, Nup88/rNup84 component; [PTHR13257] NUCLEOPORIN NUP84-RELATED 84.99 0.7352 80 Mapoly0132s0002 [GO:0008270] zinc ion binding; [PF01529] DHHC palmitoyltransferase; [PTHR22883] ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN 85.08 0.6251 81 Mapoly0016s0130 [PF14817] HAUS augmin-like complex subunit 5; [GO:0051225] spindle assembly 86.26 0.7512 82 Mapoly0051s0073 [PF14675] FANCI solenoid 1; [PTHR21818:SF0] SUBFAMILY NOT NAMED; [PF14680] FANCI helical domain 2; [KOG4553] Uncharacterized conserved protein; [K10895] fanconi anemia group I protein; [PF14679] FANCI helical domain 1; [GO:0006281] DNA repair; [PF14678] FANCI solenoid 4; [PTHR21818] BC025462 PROTEIN; [PF14676] FANCI solenoid 2 86.88 0.7491 83 Mapoly0005s0056 [GO:0005524] ATP binding; [PTHR11752] HELICASE SKI2W; [KOG0947] Cytoplasmic exosomal RNA helicase SKI2, DEAD-box superfamily; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF08148] DSHCT (NUC185) domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [PF13234] rRNA-processing arch domain; [GO:0003676] nucleic acid binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [K12599] antiviral helicase SKI2 [EC:3.6.4.-] 87.86 0.7285 84 Mapoly0010s0012 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF06461] Domain of Unknown Function (DUF1086); [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00176] SNF2 family N-terminal domain; [PF06465] Domain of Unknown Function (DUF1087); [3.6.4.12] DNA helicase.; [PF00271] Helicase conserved C-terminal domain; [K11643] chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12]; [KOG0384] Chromodomain-helicase DNA-binding protein 87.91 0.7610 85 Mapoly0010s0094 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [PF00454] Phosphatidylinositol 3- and 4-kinase; [KOG0889] Histone acetyltransferase SAGA, TRRAP/TRA1 component, PI-3 kinase superfamily; [PTHR11139:SF1] ATM-RELATED; [K08874] transformation/transcription domain-associated protein; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED 88.74 0.7448 86 Mapoly0015s0043 [3.1.2.15] Ubiquitin thiolesterase.; [PF00443] Ubiquitin carboxyl-terminal hydrolase; [K11858] ubiquitin carboxyl-terminal hydrolase 48 [EC:3.1.2.15]; [GO:0005515] protein binding; [GO:0006511] ubiquitin-dependent protein catabolic process; [PTHR24006:SF100] SUBFAMILY NOT NAMED; [KOG1863] Ubiquitin carboxyl-terminal hydrolase; [PF00240] Ubiquitin family; [PTHR24006] FAMILY NOT NAMED 88.95 0.7308 87 Mapoly0014s0195 [PTHR10641:SF17] CELL DIVISION CYCLE 5-LIKE PROTEIN; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [PF13921] Myb-like DNA-binding domain; [PF11831] pre-mRNA splicing factor component; [K12860] pre-mRNA-splicing factor CDC5/CEF1 91.39 0.7344 88 Mapoly0021s0012 [PF00443] Ubiquitin carboxyl-terminal hydrolase; [GO:0006511] ubiquitin-dependent protein catabolic process; [PF02810] SEC-C motif; [KOG1865] Ubiquitin carboxyl-terminal hydrolase; [PTHR24006] FAMILY NOT NAMED; [PF01753] MYND finger 92.41 0.7156 89 Mapoly0010s0191 [PF04055] Radical SAM superfamily; [PTHR13930] RSAFD1-RELATED; [PF00258] Flavodoxin; [PF08608] Wyosine base formation; [GO:0016491] oxidoreductase activity; [PTHR13930:SF0] SUBFAMILY NOT NAMED; [GO:0003824] catalytic activity; [GO:0051536] iron-sulfur cluster binding; [KOG1160] Fe-S oxidoreductase; [GO:0010181] FMN binding 92.66 0.7352 90 Mapoly0197s0017 [PTHR10751] GUANYLATE BINDING PROTEIN; [KOG1003] Actin filament-coating protein tropomyosin; [PTHR10751:SF2] GUANYLATE BINDING PROTEIN; [PF02263] Guanylate-binding protein, N-terminal domain; [GO:0003924] GTPase activity; [GO:0005525] GTP binding; [PF02841] Guanylate-binding protein, C-terminal domain 92.66 0.6991 91 Mapoly0035s0137 [GO:0005643] nuclear pore; [PTHR10350:SF6] NUCLEOPORIN 155; [PF03177] Non-repetitive/WGA-negative nucleoporin C-terminal; [K14312] nuclear pore complex protein Nup155; [KOG1900] Nuclear pore complex, Nup155 component (D Nup154, sc Nup157/Nup170); [GO:0006913] nucleocytoplasmic transport; [PF08801] Nup133 N terminal like; [GO:0017056] structural constituent of nuclear pore; [PTHR10350] NUCLEAR PORE COMPLEX PROTEIN NUP155 93.27 0.7544 92 Mapoly0002s0125 [PTHR25040] FAMILY NOT NAMED; [PF11926] Domain of unknown function (DUF3444); [PTHR25040:SF79] SUBFAMILY NOT NAMED; [PF00226] DnaJ domain 93.53 0.7569 93 Mapoly0006s0254 [PTHR13026:SF0] SUBFAMILY NOT NAMED; [PTHR13026] NNP-1 PROTEIN (NOVEL NUCLEAR PROTEIN 1) (NOP52); [GO:0030688] preribosome, small subunit precursor; [PF05997] Nucleolar protein,Nop52; [GO:0006364] rRNA processing 93.98 0.7167 94 Mapoly0004s0306 [KOG1871] Ubiquitin-specific protease; [3.1.2.15] Ubiquitin thiolesterase.; [PF00443] Ubiquitin carboxyl-terminal hydrolase; [GO:0006511] ubiquitin-dependent protein catabolic process; [K11841] ubiquitin carboxyl-terminal hydrolase 10 [EC:3.1.2.15]; [PTHR24006] FAMILY NOT NAMED 94.02 0.6375 95 Mapoly0022s0165 [GO:0003714] transcription corepressor activity; [PF12070] Protein of unknown function (DUF3550/UPF0682); [PTHR21243] FAMILY NOT NAMED; [GO:0006351] transcription, DNA-dependent 94.87 0.6281 96 Mapoly0034s0031 [GO:0007094] mitotic spindle assembly checkpoint; [K06638] mitotic spindle assembly checkpoint protein MAD1; [KOG4593] Mitotic checkpoint protein MAD1; [PTHR23168] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 (MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1); [PF05557] Mitotic checkpoint protein; [PTHR23168:SF0] SUBFAMILY NOT NAMED 99.24 0.7492 97 Mapoly0167s0015 [KOG1076] Translation initiation factor 3, subunit c (eIF-3c); [K03252] translation initiation factor eIF-3 subunit 8; [PF05470] Eukaryotic translation initiation factor 3 subunit 8 N-terminus; [PTHR13937:SF0] SUBFAMILY NOT NAMED; [GO:0003743] translation initiation factor activity; [GO:0005515] protein binding; [PTHR13937] EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 (EIF3S8)-RELATED; [GO:0031369] translation initiation factor binding; [PF01399] PCI domain; [GO:0006413] translational initiation; [GO:0005852] eukaryotic translation initiation factor 3 complex 99.40 0.7018 98 Mapoly0037s0026 [PTHR15598] AUTOANTIGEN RCD8; [GO:0005515] protein binding; [KOG1916] Nuclear protein, contains WD40 repeats; [K12616] enhancer of mRNA-decapping protein 4; [PF00400] WD domain, G-beta repeat 100.12 0.6900 99 Mapoly0100s0047 [KOG3263] Nucleic acid binding protein; [PTHR22849] WDSAM1 PROTEIN; [GO:0016567] protein ubiquitination; [GO:0004842] ubiquitin-protein ligase activity; [PF04564] U-box domain 101.33 0.6480 100 Mapoly0010s0152 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PTHR13561:SF5] DNA REPLICATION REGULATOR DPB11; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 102.75 0.7486 101 Mapoly0072s0051 [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [KOG0597] Serine-threonine protein kinase FUSED; [GO:0006468] protein phosphorylation 103.54 0.7472 102 Mapoly0042s0035 [PF01433] Peptidase family M1; [GO:0008237] metallopeptidase activity; [3.4.11.2] Membrane alanyl aminopeptidase.; [GO:0008270] zinc ion binding; [PTHR11533] PROTEASE M1 ZINC METALLOPROTEASE; [KOG1046] Puromycin-sensitive aminopeptidase and related aminopeptidases; [K01256] aminopeptidase N [EC:3.4.11.2]; [GO:0006508] proteolysis; [PF11940] Domain of unknown function (DUF3458) 105.74 0.6768 103 Mapoly0060s0110 [PF15072] Domain of unknown function (DUF4539); [PTHR14523] FAMILY NOT NAMED; [PTHR14523:SF1] SUBFAMILY NOT NAMED 106.11 0.7379 104 Mapoly0109s0022 [GO:0016020] membrane; [PTHR13302] CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3; [GO:0005801] cis-Golgi network; [GO:0006886] intracellular protein transport; [KOG2604] Subunit of cis-Golgi transport vesicle tethering complex - Sec34p; [PF04136] Sec34-like family 106.78 0.6898 105 Mapoly0020s0107 [KOG4626] O-linked N-acetylglucosamine transferase OGT; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13432] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat; [PF13844] Glycosyl transferase family 41; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR 108.44 0.7210 106 Mapoly0042s0086 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K08737] DNA mismatch repair protein MSH6; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PTHR11361:SF31] MUTS HOMOLOG 6, MSH6; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 108.78 0.7255 107 Mapoly0032s0010 - 110.55 0.7509 108 Mapoly0045s0061 [KOG1081] Transcription factor NSD1 and related SET domain proteins; [GO:0005515] protein binding; [PF00856] SET domain; [PTHR22884] SET DOMAIN PROTEINS 110.84 0.7312 109 Mapoly0005s0161 [GO:0003677] DNA binding; [PTHR13451:SF0] SUBFAMILY NOT NAMED; [3.1.22.-] Endodeoxyribonucleases producing other than 5'-phosphomonoesters.; [K08991] crossover junction endonuclease MUS81 [EC:3.1.22.-]; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PF02732] ERCC4 domain 111.00 0.6990 110 Mapoly0069s0084 [3.6.5.5] Dynamin GTPase.; [KOG0446] Vacuolar sorting protein VPS1, dynamin, and related proteins; [K01528] dynamin GTPase [EC:3.6.5.5]; [PF02212] Dynamin GTPase effector domain; [PF00350] Dynamin family; [PTHR11566] DYNAMIN; [GO:0003924] GTPase activity; [PTHR11566:SF21] SUBFAMILY NOT NAMED; [GO:0005525] GTP binding; [PF01031] Dynamin central region 111.28 0.7052 111 Mapoly0061s0069 [K09422] myb proto-oncogene protein, plant; [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding; [PF13921] Myb-like DNA-binding domain 111.86 0.7124 112 Mapoly0066s0020 [PF13812] Pentatricopeptide repeat domain; [PF12854] PPR repeat; [PF01535] PPR repeat; [PTHR24015] FAMILY NOT NAMED; [PF13041] PPR repeat family 113.31 0.7219 113 Mapoly0025s0106 [PF14635] Helix-hairpin-helix motif; [GO:0003677] DNA binding; [PTHR10145:SF6] TRANSCRIPTION ELONGATION FACTOR SPT6-RELATED; [PF14641] Helix-turn-helix DNA-binding domain of SPT6; [GO:0006357] regulation of transcription from RNA polymerase II promoter; [GO:0005515] protein binding; [PF14633] SH2 domain; [PF14639] Holliday-junction resolvase-like of SPT6; [PF14878] Death-like domain of SPT6; [GO:0032784] regulation of DNA-dependent transcription, elongation; [PF14632] Acidic N-terminal SPT6; [K11292] transcription elongation factor SPT6; [KOG1856] Transcription elongation factor SPT6; [PTHR10145] TRANSCRIPTION ELONGATION FACTOR SPT6 114.95 0.7460 114 Mapoly0015s0081 [PF11707] Ribosome 60S biogenesis N-terminal; [PTHR13500] NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1 115.08 0.7421 115 Mapoly0065s0001 - 116.23 0.5457 116 Mapoly0078s0037 [KOG0987] DNA helicase PIF1/RRM3; [PF05970] PIF1-like helicase; [GO:0006281] DNA repair; [PTHR23274] DNA HELICASE-RELATED; [GO:0003678] DNA helicase activity; [GO:0000723] telomere maintenance 117.37 0.7049 117 Mapoly0057s0099 [KOG4817] Unnamed protein 117.67 0.7520 118 Mapoly0049s0040 [GO:0005524] ATP binding; [PTHR24058:SF23] DUAL-SPECIFICITY TYROSINE REGULATED PROTEIN KINASE 2; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24058] DUAL SPECIFICITY PROTEIN KINASE; [KOG0667] Dual-specificity tyrosine-phosphorylation regulated kinase; [GO:0006468] protein phosphorylation 118.05 0.7238 119 Mapoly0019s0008 [GO:0003723] RNA binding; [PF10596] U6-snRNA interacting domain of PrP8; [PF08083] PROCN (NUC071) domain; [GO:0005515] protein binding; [GO:0005681] spliceosomal complex; [PTHR11140] PRE-MRNA SPLICING FACTOR PRP8; [PTHR11140:SF0] SUBFAMILY NOT NAMED; [PF01398] JAB1/Mov34/MPN/PAD-1 ubiquitin protease; [GO:0030623] U5 snRNA binding; [PF10597] U5-snRNA binding site 2 of PrP8; [KOG1795] U5 snRNP spliceosome subunit; [GO:0000398] mRNA splicing, via spliceosome; [PF12134] PRP8 domain IV core; [PF10598] RNA recognition motif of the spliceosomal PrP8; [K12856] pre-mRNA-processing factor 8; [GO:0017070] U6 snRNA binding; [PF08082] PRO8NT (NUC069), PrP8 N-terminal domain; [PF08084] PROCT (NUC072) domain 118.37 0.7209 120 Mapoly0010s0036 [KOG2002] TPR-containing nuclear phosphoprotein that regulates K(+) uptake; [PF07719] Tetratricopeptide repeat; [PTHR14027:SF2] TPR REPEAT NUCLEAR PHOSPHOPROTEIN; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13174] Tetratricopeptide repeat; [PF13181] Tetratricopeptide repeat; [PF13424] Tetratricopeptide repeat; [PTHR14027] TPR REPEAT NUCLEAR PHOSPHOPROTEIN/CTR9; [PF00515] Tetratricopeptide repeat 119.10 0.7372 121 Mapoly0091s0056 [PF05918] Apoptosis inhibitory protein 5 (API5); [KOG2213] Apoptosis inhibitor 5/fibroblast growth factor 2-interacting factor 2, and related proteins; [PTHR12758] APOPTOSIS INHIBITOR 5-RELATED 120.04 0.7212 122 Mapoly0030s0102 [PF08317] Spc7 kinetochore protein 120.12 0.7420 123 Mapoly0023s0118 [PTHR12446] TESMIN/TSO1-RELATED; [PF03638] Tesmin/TSO1-like CXC domain, cysteine-rich domain 120.45 0.7338 124 Mapoly0014s0197 [KOG4822] Predicted nuclear membrane protein involved in mRNA transport and sex determination via splicing modulation; [PTHR23185:SF0] SUBFAMILY NOT NAMED; [PTHR23185] UNCHARACTERIZED 125.33 0.7241 125 Mapoly0102s0024 [GO:0006355] regulation of transcription, DNA-dependent; [PF14443] DBC1; [KOG3227] Calcium-responsive transcription coactivator; [PTHR14304] P30 DBC PROTEIN 125.73 0.7427 126 Mapoly0112s0026 [PF11987] Translation-initiation factor 2; [KOG1144] Translation initiation factor 5B (eIF-5B); [PF00009] Elongation factor Tu GTP binding domain; [GO:0003924] GTPase activity; [PF14578] Elongation factor Tu domain 4; [PTHR23115] TRANSLATION FACTOR; [K03243] translation initiation factor eIF-5B; [GO:0005525] GTP binding; [PF03144] Elongation factor Tu domain 2 127.22 0.7369 127 Mapoly0059s0047 [PTHR23092] TOPOISOMERASE-RELATED PROTEIN; [PF01909] Nucleotidyltransferase domain; [GO:0016779] nucleotidyltransferase activity; [PTHR23092:SF15] SUBFAMILY NOT NAMED; [PF10539] Development and cell death domain 128.28 0.6866 128 Mapoly0033s0024 [GO:0005524] ATP binding; [K14572] midasin; [PF07728] AAA domain (dynein-related subfamily); [GO:0016887] ATPase activity; [KOG1808] AAA ATPase containing von Willebrand factor type A (vWA) domain; [PTHR22908] MIDASIN-RELATED 129.23 0.6966 129 Mapoly0015s0206 [PF05236] Transcription initiation factor TFIID component TAF4 family; [GO:0006352] DNA-dependent transcription, initiation; [PTHR15138] FAMILY NOT NAMED; [PF12174] RCD1-SRO-TAF4 (RST) plant domain; [GO:0005669] transcription factor TFIID complex 129.38 0.7149 130 Mapoly0004s0300 [GO:0005524] ATP binding; [PTHR11909:SF7] CELL DIVISION CONTROL PROTEIN 7; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K02214] cell division control protein 7 [EC:2.7.11.1]; [KOG1167] Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination; [GO:0006468] protein phosphorylation; [PTHR11909] CASEIN KINASE-RELATED 130.26 0.7361 131 Mapoly0002s0238 [GO:0003847] 1-alkyl-2-acetylglycerophosphocholine esterase activity; [GO:0016042] lipid catabolic process; [3.1.1.47] 1-alkyl-2-acetylglycerophosphocholine esterase.; [K01062] 1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47]; [PTHR10272] PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE; [PF03403] Platelet-activating factor acetylhydrolase, isoform II; [KOG3847] Phospholipase A2 (platelet-activating factor acetylhydrolase in humans) 130.54 0.5460 132 Mapoly0069s0061 [GO:0004677] DNA-dependent protein kinase activity; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [K06642] DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]; [PF08163] NUC194 domain; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0005634] nucleus; [PF00454] Phosphatidylinositol 3- and 4-kinase; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [GO:0006303] double-strand break repair via nonhomologous end joining 130.81 0.6875 133 Mapoly0146s0008 [GO:0008641] small protein activating enzyme activity; [GO:0005524] ATP binding; [PF09358] Ubiquitin-activating enzyme e1 C-terminal domain; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [KOG2012] Ubiquitin activating enzyme UBA1; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [K03178] ubiquitin-activating enzyme E1 [EC:6.3.2.19]; [PTHR10953:SF4] UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 1 (UBIQUITIN-ACTIVATING ENZYME E1) 132.25 0.6434 134 Mapoly0092s0032 [PTHR22597] POLYCOMB GROUP PROTEIN; [PTHR22597:SF0] SUBFAMILY NOT NAMED; [PF09733] VEFS-Box of polycomb protein 132.33 0.7238 135 Mapoly0081s0047 [PF00773] RNB domain; [PF13638] PIN domain; [3.1.13.-] Exoribonucleases producing 5'-phosphomonoesters.; [K12585] exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]; [PTHR23355] RIBONUCLEASE; [KOG2102] Exosomal 3'-5' exoribonuclease complex, subunit Rrp44/Dis3 133.36 0.7007 136 Mapoly0052s0095 [GO:0005643] nuclear pore; [PTHR31344:SF0] SUBFAMILY NOT NAMED; [K14310] nuclear pore complex protein Nup205; [PF11894] Protein of unknown function (DUF3414); [PTHR31344] FAMILY NOT NAMED; [KOG1835] Uncharacterized conserved protein 135.09 0.7037 137 Mapoly0011s0047 [PTHR12972] DOWNSTREAM NEIGHBOR OF SON 136.28 0.7020 138 Mapoly0120s0004 [PF00488] MutS domain V; [GO:0005524] ATP binding; [K08735] DNA mismatch repair protein MSH2; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PTHR11361:SF35] MUTS HOMOLOG 2, MSH2; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III; [KOG0219] Mismatch repair ATPase MSH2 (MutS family); [PF05190] MutS family domain IV 137.56 0.7208 139 Mapoly0024s0108 [PF13371] Tetratricopeptide repeat; [PTHR23082] TRANSCRIPTION INITIATION FACTOR IIIC (TFIIIC), POLYPEPTIDE 3-RELATED; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13174] Tetratricopeptide repeat; [KOG2076] RNA polymerase III transcription factor TFIIIC 138.14 0.6803 140 Mapoly0042s0123 [K12875] apoptotic chromatin condensation inducer in the nucleus; [GO:0003676] nucleic acid binding; [PTHR14127] APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; [PF02037] SAP domain 138.82 0.7275 141 Mapoly0063s0038 [PTHR22050] RW1 PROTEIN HOMOLOG; [PF12371] Protein of unknown function (DUF3651) 139.10 0.6234 142 Mapoly0114s0009 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [PF00514] Armadillo/beta-catenin-like repeat; [GO:0005515] protein binding; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [KOG0240] Kinesin (SMY1 subfamily); [GO:0008017] microtubule binding; [PTHR24115:SF221] SUBFAMILY NOT NAMED; [GO:0003777] microtubule motor activity 139.60 0.6921 143 Mapoly0034s0119 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 139.77 0.7340 144 Mapoly0051s0016 [PF13831] PHD-finger; [PF05964] F/Y-rich N-terminus; [GO:0005515] protein binding; [PF13832] PHD-zinc-finger like domain; [PF00856] SET domain; [PTHR13793] PHD FINGER PROTEINS; [PF00855] PWWP domain; [GO:0005634] nucleus; [PF05965] F/Y rich C-terminus 141.74 0.7249 145 Mapoly0015s0126 [GO:0008641] small protein activating enzyme activity; [GO:0005524] ATP binding; [K10685] ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19]; [KOG2013] SMT3/SUMO-activating complex, catalytic component UBA2; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [PF14732] Ubiquitin/SUMO-activating enzyme ubiquitin-like domain 142.21 0.7130 146 Mapoly0032s0018 [KOG0796] Spliceosome subunit 142.68 0.7181 147 Mapoly0002s0308 [GO:0005524] ATP binding; [PF02359] Cell division protein 48 (CDC48), N-terminal domain; [PF02933] Cell division protein 48 (CDC48), domain 2; [PF00004] ATPase family associated with various cellular activities (AAA); [K13525] transitional endoplasmic reticulum ATPase; [PTHR23077] AAA-FAMILY ATPASE; [KOG0730] AAA+-type ATPase 143.87 0.6169 148 Mapoly0105s0035 [PTHR12341] 5'-3' EXORIBONUCLEASE; [PF03159] XRN 5'-3' exonuclease N-terminus; [K12619] 5'-3' exoribonuclease 2 [EC:3.1.13.-]; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [3.1.13.-] Exoribonucleases producing 5'-phosphomonoesters.; [GO:0003676] nucleic acid binding; [GO:0004527] exonuclease activity 144.11 0.7175 149 Mapoly0083s0034 - 144.44 0.6975 150 Mapoly0015s0183 [GO:0000922] spindle pole; [PF04130] Spc97 / Spc98 family; [GO:0000226] microtubule cytoskeleton organization; [GO:0005815] microtubule organizing center; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN 145.42 0.6456 151 Mapoly0013s0059 [GO:0005515] protein binding; [PF02213] GYF domain; [PTHR14445] GRB10 INTERACTING GYF PROTEIN 145.87 0.7153 152 Mapoly0045s0049 - 148.58 0.6727 153 Mapoly0113s0005 - 149.52 0.7072 154 Mapoly0114s0035 [PTHR31169] FAMILY NOT NAMED; [PF10497] Zinc-finger domain of monoamine-oxidase A repressor R1 149.97 0.7036 155 Mapoly0006s0149 [KOG4732] Uncharacterized conserved protein; [PTHR21483] FAMILY NOT NAMED; [PF08620] RPAP1-like, C-terminal; [PF08621] RPAP1-like, N-terminal 152.26 0.5965 156 Mapoly0019s0115 [PTHR23002] ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN; [PF14392] Zinc knuckle; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding 152.32 0.6813 157 Mapoly0105s0004 [PTHR31267] FAMILY NOT NAMED 152.73 0.7217 158 Mapoly0001s0369 [K12879] THO complex subunit 2; [PF11262] Transcription factor/nuclear export subunit protein 2; [PTHR21597] THO2 PROTEIN; [PF11732] Transcription- and export-related complex subunit; [PTHR21597:SF0] SUBFAMILY NOT NAMED; [KOG1874] KEKE-like motif-containing transcription regulator (Rlr1)/suppressor of sin4 153.44 0.7217 159 Mapoly0005s0138 - 154.97 0.7002 160 Mapoly0011s0137 [K03504] DNA polymerase delta subunit 3; [GO:0006260] DNA replication; [PTHR17598] FAMILY NOT NAMED; [PF09507] DNA polymerase subunit Cdc27; [GO:0005634] nucleus 155.02 0.7088 161 Mapoly0101s0048 [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat 155.70 0.7186 162 Mapoly0009s0229 [PF01987] Mitochondrial biogenesis AIM24 155.72 0.7147 163 Mapoly0098s0023 [PTHR19378] GOLGIN- RELATED; [PF14932] HAUS augmin-like complex subunit 3; [GO:0051225] spindle assembly; [GO:0070652] HAUS complex; [PTHR19378:SF0] SUBFAMILY NOT NAMED 156.27 0.6971 164 Mapoly0094s0004 [GO:0003677] DNA binding; [PTHR22970:SF1] SUBFAMILY NOT NAMED; [PTHR22970] FAMILY NOT NAMED; [PF01388] ARID/BRIGHT DNA binding domain; [GO:0005622] intracellular 157.28 0.7091 165 Mapoly0098s0032 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [PF11721] Di-glucose binding within endoplasmic reticulum; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 157.42 0.7226 166 Mapoly0113s0048 [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [KOG1408] WD40 repeat protein; [PF00400] WD domain, G-beta repeat 158.16 0.7221 167 Mapoly0125s0020 [PF06972] Protein of unknown function (DUF1296); [PTHR12758] APOPTOSIS INHIBITOR 5-RELATED; [PTHR12758:SF13] APOPTOSIS INHIBITOR 5-RELATED 158.19 0.6561 168 Mapoly0151s0018 [PF00917] MATH domain; [GO:0005515] protein binding; [PTHR24006] FAMILY NOT NAMED 159.37 0.7241 169 Mapoly0051s0023 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III 159.50 0.7257 170 Mapoly0121s0051 [KOG1003] Actin filament-coating protein tropomyosin 159.51 0.7242 171 Mapoly0074s0043 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [GO:0003729] mRNA binding 159.90 0.7080 172 Mapoly0020s0130 [PF06839] GRF zinc finger; [GO:0008270] zinc ion binding 159.92 0.7067 173 Mapoly0053s0080 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PF12230] Pre-mRNA splicing factor PRP21 like protein; [GO:0005515] protein binding; [PTHR15316:SF1] SPLICEOSOME ASSOCIATED PROTEIN 114; [PF00240] Ubiquitin family; [K12825] splicing factor 3A subunit 1; [PTHR15316] SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED; [PF01805] Surp module; [KOG0007] Splicing factor 3a, subunit 1 160.89 0.7014 174 Mapoly0043s0034 [PTHR13233] MICROSPHERULE PROTEIN 1; [GO:0005515] protein binding; [PTHR13233:SF0] SUBFAMILY NOT NAMED; [PF13325] N-terminal region of micro-spherule protein; [PF00498] FHA domain 162.17 0.7173 175 Mapoly0134s0010 [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PF12726] SEN1 N terminal; [PF13086] AAA domain; [KOG2812] Uncharacterized conserved protein; [PF13087] AAA domain 162.90 0.6778 176 Mapoly0074s0003 [GO:0003677] DNA binding; [PF12254] DNA polymerase alpha subunit p180 N terminal; [GO:0006260] DNA replication; [GO:0001882] nucleoside binding; [K02320] DNA polymerase alpha subunit A [EC:2.7.7.7]; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0006270] DNA replication initiation; [PF08996] DNA Polymerase alpha zinc finger; [KOG0970] DNA polymerase alpha, catalytic subunit; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT 162.92 0.6957 177 Mapoly0133s0013 [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10615] HISTONE ACETYLTRANSFERASE; [PF00856] SET domain 163.95 0.7170 178 Mapoly0043s0132 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00176] SNF2 family N-terminal domain; [PF06465] Domain of Unknown Function (DUF1087); [KOG0383] Predicted helicase 164.16 0.6656 179 Mapoly0078s0012 [GO:0006396] RNA processing; [PTHR11061] RNA M5U METHYLTRANSFERASE FAMILY; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0008173] RNA methyltransferase activity; [PF05958] tRNA (Uracil-5-)-methyltransferase; [GO:0046872] metal ion binding; [KOG2187] tRNA uracil-5-methyltransferase and related tRNA-modifying enzymes 164.33 0.6923 180 Mapoly0001s0481 [KOG1190] Polypyrimidine tract-binding protein; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [PTHR11546] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 165.23 0.7067 181 Mapoly0075s0058 [KOG4416] Uncharacterized conserved protein; [PF07986] Tubulin binding cofactor C; [PTHR16052] UNCHARACTERIZED 165.52 0.6600 182 Mapoly0001s0490 [PTHR21512:SF5] GB DEF: HYPOTHETICAL PROTEIN T5K6_30; [PTHR21512] FAMILY NOT NAMED; [KOG1953] Targeting complex (TRAPP) subunit; [PF08626] Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit 166.01 0.6766 183 Mapoly0074s0001 [PF03810] Importin-beta N-terminal domain; [PF08767] CRM1 C terminal; [KOG2020] Nuclear transport receptor CRM1/MSN5 (importin beta superfamily); [PTHR11223] EXPORTIN 1/5; [GO:0006886] intracellular protein transport; [PTHR11223:SF2] EXPORTIN 1 (CHROMOSOME REGION MAINTENANCE PROTEIN 1); [K14290] exportin-1; [GO:0008536] Ran GTPase binding; [PF08389] Exportin 1-like protein 166.22 0.6462 184 Mapoly0097s0064 [PTHR13710:SF1] ROTHMUND-THOMSON SYNDROME DNA HELICASE RECQ4; [GO:0005524] ATP binding; [PF11719] DNA replication and checkpoint protein; [K10730] ATP-dependent DNA helicase Q4 [EC:3.6.4.12]; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [GO:0003676] nucleic acid binding; [PF02037] SAP domain 168.07 0.7098 185 Mapoly0112s0032 [KOG2652] RNA polymerase II transcription initiation factor TFIIA, large chain; [PTHR12694] TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; [PTHR12694:SF8] TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; [PF03153] Transcription factor IIA, alpha/beta subunit; [GO:0005672] transcription factor TFIIA complex; [K03122] transcription initiation factor TFIIA large subunit; [GO:0006367] transcription initiation from RNA polymerase II promoter 168.53 0.6604 186 Mapoly0061s0018 [KOG2318] Uncharacterized conserved protein; [GO:0005634] nucleus; [PF08159] NUC153 domain; [PTHR12202] UNCHARACTERIZED 169.23 0.6610 187 Mapoly0158s0032 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [K10728] topoisomerase (DNA) II binding protein 1; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 170.80 0.6803 188 Mapoly0005s0067 [PTHR15242:SF0] SUBFAMILY NOT NAMED; [PTHR15242] SPLICING FACTOR, ARGININE/SERINE-RICH 2,RNAP C-TERM INTERACTING PROTEIN; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 170.82 0.7073 189 Mapoly0039s0061 [PF12612] Tubulin folding cofactor D C terminal; [KOG1943] Beta-tubulin folding cofactor D; [PTHR12658] BETA-TUBULIN COFACTOR D 172.51 0.6866 190 Mapoly0054s0075 [PTHR17695] UNCHARACTERIZED; [PTHR17695:SF11] SUBFAMILY NOT NAMED; [PF07539] Down-regulated in metastasis; [KOG1823] DRIM (Down-regulated in metastasis)-like proteins 173.64 0.7089 191 Mapoly0008s0009 - 174.26 0.6168 192 Mapoly0092s0013 [GO:0003723] RNA binding; [PTHR13326] TRNA PSEUDOURIDINE SYNTHASE D; [GO:0001522] pseudouridine synthesis; [GO:0009451] RNA modification; [PF01142] tRNA pseudouridine synthase D (TruD); [GO:0009982] pseudouridine synthase activity; [KOG2339] Uncharacterized conserved protein 174.53 0.6778 193 Mapoly0098s0013 [KOG1634] Predicted transcription factor DATF1, contains PHD and TFS2M domains; [PF07500] Transcription factor S-II (TFIIS), central domain; [PTHR11477] TRANSCRIPTION ELONGATION FACTOR S-II; [GO:0006351] transcription, DNA-dependent; [PF07744] SPOC domain 175.48 0.6901 194 Mapoly0051s0060 [PTHR31399:SF0] SUBFAMILY NOT NAMED; [PF03121] Herpesviridae UL52/UL70 DNA primase; [GO:0006260] DNA replication; [GO:0003896] DNA primase activity; [PTHR31399] FAMILY NOT NAMED 175.77 0.6869 195 Mapoly0081s0051 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [2.7.11.1] Non-specific serine/threonine protein kinase.; [PF11640] Telomere-length maintenance and DNA damage repair; [PF00454] Phosphatidylinositol 3- and 4-kinase; [GO:0004674] protein serine/threonine kinase activity; [PF02260] FATC domain; [K04728] ataxia telangectasia mutated family protein [EC:2.7.11.1]; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED 175.81 0.6540 196 Mapoly0043s0108 [GO:0006355] regulation of transcription, DNA-dependent; [PTHR13831] MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS; [GO:0005515] protein binding; [PF07569] TUP1-like enhancer of split; [PTHR13831:SF0] SUBFAMILY NOT NAMED; [GO:0005634] nucleus; [K11293] protein HIRA/HIR1; [KOG0973] Histone transcription regulator HIRA, WD repeat superfamily; [PF00400] WD domain, G-beta repeat 178.73 0.6667 197 Mapoly0189s0011 [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain 178.97 0.7014 198 Mapoly0096s0011 [PTHR12436] 80 KDA MCM3-ASSOCIATED PROTEIN; [PF03399] SAC3/GANP/Nin1/mts3/eIF-3 p25 family 179.45 0.6969 199 Mapoly0005s0174 [GO:0005524] ATP binding; [KOG0933] Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E); [GO:0007076] mitotic chromosome condensation; [GO:0005515] protein binding; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0000796] condensin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PTHR18937:SF9] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC2; [K06674] structural maintenance of chromosome 2; [PF06470] SMC proteins Flexible Hinge Domain 179.60 0.7144 200 Mapoly0239s0007 - 180.30 0.5310