Guide Gene
- Gene ID
- Mapoly0042s0049
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- -
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0042s0049 - 0.00 1.0000 1 Mapoly0138s0046 [KOG1803] DNA helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PF13086] AAA domain; [PF13087] AAA domain 1.00 0.8778 2 Mapoly0043s0064 [PF10979] Protein of unknown function (DUF2786) 3.00 0.8737 3 Mapoly0061s0085 [PF14868] Domain of unknown function (DUF4487) 3.46 0.8652 4 Mapoly0133s0013 [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10615] HISTONE ACETYLTRANSFERASE; [PF00856] SET domain 3.46 0.8750 5 Mapoly0113s0005 - 4.24 0.8549 6 Mapoly0041s0060 [GO:0003677] DNA binding; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PTHR13451:SF3] gb def: Hypothetical protein F6I18.220 (Hypothetical protein AT4g30870); [PF02732] ERCC4 domain 6.00 0.8635 7 Mapoly0008s0081 [PTHR21286] NUCLEAR PORE COMPLEX PROTEIN NUP160; [K14303] nuclear pore complex protein Nup160; [KOG4521] Nuclear pore complex, Nup160 component; [PF11715] Nucleoporin Nup120/160 6.32 0.8524 8 Mapoly0043s0108 [GO:0006355] regulation of transcription, DNA-dependent; [PTHR13831] MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS; [GO:0005515] protein binding; [PF07569] TUP1-like enhancer of split; [PTHR13831:SF0] SUBFAMILY NOT NAMED; [GO:0005634] nucleus; [K11293] protein HIRA/HIR1; [KOG0973] Histone transcription regulator HIRA, WD repeat superfamily; [PF00400] WD domain, G-beta repeat 8.12 0.7916 9 Mapoly0023s0090 [PF00249] Myb-like DNA-binding domain; [GO:0003682] chromatin binding; [PTHR22929] RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR B; [PTHR22929:SF0] SUBFAMILY NOT NAMED 8.94 0.8354 10 Mapoly0039s0061 [PF12612] Tubulin folding cofactor D C terminal; [KOG1943] Beta-tubulin folding cofactor D; [PTHR12658] BETA-TUBULIN COFACTOR D 10.00 0.8282 11 Mapoly0060s0110 [PF15072] Domain of unknown function (DUF4539); [PTHR14523] FAMILY NOT NAMED; [PTHR14523:SF1] SUBFAMILY NOT NAMED 10.49 0.8517 12 Mapoly0033s0057 [2.3.1.-] Transferring groups other than amino-acyl groups.; [PTHR11076:SF1] ESTABLISHMENT OF COHESION 1 (ECO1) HOMOLOG; [PF13880] ESCO1/2 acetyl-transferase; [PF13878] zinc-finger of acetyl-transferase ESCO; [KOG3014] Protein involved in establishing cohesion between sister chromatids during DNA replication; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [K11268] N-acetyltransferase [EC:2.3.1.-] 11.40 0.8639 13 Mapoly0016s0079 [GO:0005524] ATP binding; [KOG2680] DNA helicase TIP49, TBP-interacting protein; [3.6.4.12] DNA helicase.; [PF06068] TIP49 C-terminus; [GO:0043141] ATP-dependent 5'-3' DNA helicase activity; [K11338] RuvB-like protein 2 [EC:3.6.4.12]; [GO:0003678] DNA helicase activity; [PTHR11093] RUVB-RELATED REPTIN AND PONTIN; [PTHR11093:SF2] RUVB-LIKE 2 (REPTIN) 12.17 0.8177 14 Mapoly0051s0023 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III 12.33 0.8570 15 Mapoly0034s0031 [GO:0007094] mitotic spindle assembly checkpoint; [K06638] mitotic spindle assembly checkpoint protein MAD1; [KOG4593] Mitotic checkpoint protein MAD1; [PTHR23168] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 (MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1); [PF05557] Mitotic checkpoint protein; [PTHR23168:SF0] SUBFAMILY NOT NAMED 12.85 0.8463 16 Mapoly0034s0011 [PF09133] SANTA (SANT Associated) 12.96 0.8513 17 Mapoly0009s0015 [PF00078] Reverse transcriptase (RNA-dependent DNA polymerase); [PTHR12066] TELOMERASE REVERSE TRANSCRIPTASE; [GO:0003964] RNA-directed DNA polymerase activity; [K11126] telomerase reverse transcriptase [EC:2.7.7.49]; [PTHR12066:SF0] SUBFAMILY NOT NAMED; [2.7.7.49] RNA-directed DNA polymerase.; [PF12009] Telomerase ribonucleoprotein complex - RNA binding domain; [KOG1005] Telomerase catalytic subunit/reverse transcriptase TERT 14.07 0.8371 18 Mapoly0005s0138 - 15.10 0.8172 19 Mapoly0061s0120 [PTHR13269] UNCHARACTERIZED; [PTHR13269:SF6] SUBFAMILY NOT NAMED; [PF09531] Nucleoporin protein Ndc1-Nup 15.23 0.8256 20 Mapoly0005s0051 [GO:0003723] RNA binding; [GO:0000339] RNA cap binding; [GO:0045292] mRNA cis splicing, via spliceosome; [GO:0051028] mRNA transport; [PF02854] MIF4G domain; [GO:0005515] protein binding; [KOG1104] Nuclear cap-binding complex, subunit NCBP1/CBP80; [K12882] nuclear cap-binding protein subunit 1; [GO:0016070] RNA metabolic process; [PTHR12412] CAP BINDING PROTEIN; [GO:0005846] nuclear cap binding complex; [PF09090] MIF4G like; [PF09088] MIF4G like 15.49 0.8420 21 Mapoly0042s0086 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K08737] DNA mismatch repair protein MSH6; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PTHR11361:SF31] MUTS HOMOLOG 6, MSH6; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 15.87 0.8268 22 Mapoly0070s0053 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF09382] RQC domain; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [K10901] bloom syndrome protein [EC:3.6.4.12]; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 16.31 0.8355 23 Mapoly0107s0034 [3.5.1.98] Histone deacetylase.; [KOG1342] Histone deacetylase complex, catalytic component RPD3; [K06067] histone deacetylase 1/2 [EC:3.5.1.98]; [PF00850] Histone deacetylase domain; [PTHR10625] HISTONE DEACETYLASE 16.61 0.8079 24 Mapoly0069s0072 [GO:0005524] ATP binding; [GO:0008026] ATP-dependent helicase activity; [3.6.4.13] RNA helicase.; [PF13307] Helicase C-terminal domain; [PTHR11472] DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; [GO:0006139] nucleobase-containing compound metabolic process; [GO:0003676] nucleic acid binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [K11273] chromosome transmission fidelity protein 1 [EC:3.6.4.13] 17.23 0.8205 25 Mapoly0113s0048 [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [KOG1408] WD40 repeat protein; [PF00400] WD domain, G-beta repeat 17.55 0.8596 26 Mapoly0019s0119 - 19.42 0.8488 27 Mapoly0072s0079 [PF11717] RNA binding activity-knot of a chromodomain; [K11339] mortality factor 4-like protein 1; [GO:0005634] nucleus; [PTHR10880] MORTALITY FACTOR 4-LIKE PROTEIN; [PF05712] MRG 20.20 0.8318 28 Mapoly0078s0037 [KOG0987] DNA helicase PIF1/RRM3; [PF05970] PIF1-like helicase; [GO:0006281] DNA repair; [PTHR23274] DNA HELICASE-RELATED; [GO:0003678] DNA helicase activity; [GO:0000723] telomere maintenance 21.73 0.7952 29 Mapoly0122s0062 [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 22.58 0.8386 30 Mapoly0091s0056 [PF05918] Apoptosis inhibitory protein 5 (API5); [KOG2213] Apoptosis inhibitor 5/fibroblast growth factor 2-interacting factor 2, and related proteins; [PTHR12758] APOPTOSIS INHIBITOR 5-RELATED 23.66 0.8148 31 Mapoly0004s0250 [GO:0005643] nuclear pore; [PF07817] GLE1-like protein; [GO:0016973] poly(A)+ mRNA export from nucleus; [KOG2412] Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor; [PTHR12960:SF0] SUBFAMILY NOT NAMED; [PTHR12960] GLE-1-RELATED 24.49 0.8063 32 Mapoly0079s0005 [GO:0008080] N-acetyltransferase activity; [GO:0016568] chromatin modification; [PF00583] Acetyltransferase (GNAT) family; [GO:0005634] nucleus; [GO:0004402] histone acetyltransferase activity; [GO:0016573] histone acetylation; [KOG2696] Histone acetyltransferase type b catalytic subunit; [GO:0006348] chromatin silencing at telomere; [2.3.1.48] Histone acetyltransferase.; [PTHR12046] HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT; [K11303] histone acetyltransferase 1 [EC:2.3.1.48]; [PF10394] Histone acetyl transferase HAT1 N-terminus 25.30 0.8225 33 Mapoly0098s0023 [PTHR19378] GOLGIN- RELATED; [PF14932] HAUS augmin-like complex subunit 3; [GO:0051225] spindle assembly; [GO:0070652] HAUS complex; [PTHR19378:SF0] SUBFAMILY NOT NAMED 26.15 0.7988 34 Mapoly0004s0300 [GO:0005524] ATP binding; [PTHR11909:SF7] CELL DIVISION CONTROL PROTEIN 7; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K02214] cell division control protein 7 [EC:2.7.11.1]; [KOG1167] Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination; [GO:0006468] protein phosphorylation; [PTHR11909] CASEIN KINASE-RELATED 26.72 0.8465 35 Mapoly0103s0054 [PTHR24067:SF59] UBIQUITIN-CONJUGATING ENZYME E2 T; [K13960] ubiquitin-conjugating enzyme E2 T [EC:6.3.2.19]; [PTHR24067] UBIQUITIN-CONJUGATING ENZYME E2; [GO:0016881] acid-amino acid ligase activity; [6.3.2.19] Ubiquitin--protein ligase.; [KOG0417] Ubiquitin-protein ligase; [PF00179] Ubiquitin-conjugating enzyme 27.75 0.7826 36 Mapoly0221s0003 - 27.93 0.8238 37 Mapoly0011s0047 [PTHR12972] DOWNSTREAM NEIGHBOR OF SON 28.72 0.8012 38 Mapoly0097s0045 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11752] HELICASE SKI2W; [2.7.7.7] DNA-directed DNA polymerase.; [K02349] DNA polymerase theta subunit [EC:2.7.7.7]; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF00476] DNA polymerase family A; [GO:0003676] nucleic acid binding; [GO:0003887] DNA-directed DNA polymerase activity; [KOG0950] DNA polymerase theta/eta, DEAD-box superfamily 28.77 0.7897 39 Mapoly0080s0001 [GO:0005515] protein binding; [PTHR15271] CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; [KOG1009] Chromatin assembly complex 1 subunit B/CAC2 (contains WD40 repeats); [K10751] chromatin assembly factor 1 subunit B; [PF00400] WD domain, G-beta repeat 30.40 0.8345 40 Mapoly0005s0161 [GO:0003677] DNA binding; [PTHR13451:SF0] SUBFAMILY NOT NAMED; [3.1.22.-] Endodeoxyribonucleases producing other than 5'-phosphomonoesters.; [K08991] crossover junction endonuclease MUS81 [EC:3.1.22.-]; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PF02732] ERCC4 domain 31.94 0.7708 41 Mapoly0062s0031 - 32.98 0.7899 42 Mapoly0063s0093 [PF07714] Protein tyrosine kinase; [KOG0192] Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs; [PTHR23257] SERINE-THREONINE PROTEIN KINASE; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [GO:0005543] phospholipid binding; [PF07651] ANTH domain 33.47 0.7436 43 Mapoly0042s0023 [GO:0005524] ATP binding; [2.7.12.1] Dual-specificity kinase.; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [K08866] serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]; [PTHR22974] MIXED LINEAGE PROTEIN KINASE 35.41 0.8345 44 Mapoly0031s0090 [KOG0379] Kelch repeat-containing proteins; [PF13418] Galactose oxidase, central domain; [PTHR23244] KELCH REPEAT DOMAIN; [PF13415] Galactose oxidase, central domain 35.50 0.8185 45 Mapoly0066s0041 [GO:0030915] Smc5-Smc6 complex; [PTHR21330] UNCHARACTERIZED; [GO:0019789] SUMO ligase activity; [PF11789] Zinc-finger of the MIZ type in Nse subunit; [GO:0000724] double-strand break repair via homologous recombination 37.52 0.7775 46 Mapoly0006s0290 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR10670:SF0] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A; [GO:0000166] nucleotide binding; [GO:0008270] zinc ion binding; [2.7.7.7] DNA-directed DNA polymerase.; [KOG1798] DNA polymerase epsilon, catalytic subunit A; [PF08490] Domain of unknown function (DUF1744); [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF00136] DNA polymerase family B; [GO:0008622] epsilon DNA polymerase complex; [K02324] DNA polymerase epsilon subunit 1 [EC:2.7.7.7]; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10670] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A 38.97 0.8226 47 Mapoly0130s0046 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF14493] Helix-turn-helix domain; [PF09382] RQC domain; [K10900] werner syndrome ATP-dependent helicase [EC:3.6.4.12]; [KOG0353] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 39.12 0.8059 48 Mapoly0024s0112 [GO:0005643] nuclear pore; [KOG1964] Nuclear pore complex, rNup107 component (sc Nup84); [PTHR13003] NUP107-RELATED; [GO:0006810] transport; [PF04121] Nuclear pore protein 84 / 107; [K14301] nuclear pore complex protein Nup107 39.42 0.8106 49 Mapoly0105s0060 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [K12898] heterogeneous nuclear ribonucleoprotein F/H; [KOG4211] Splicing factor hnRNP-F and related RNA-binding proteins; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED 39.99 0.8155 50 Mapoly0001s0481 [KOG1190] Polypyrimidine tract-binding protein; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [PTHR11546] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 40.99 0.7948 51 Mapoly0180s0011 - 41.42 0.6902 52 Mapoly0001s0406 [GO:0000922] spindle pole; [KOG2000] Gamma-tubulin complex, DGRIP91/SPC98 component; [PF04130] Spc97 / Spc98 family; [GO:0005856] cytoskeleton; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [GO:0007020] microtubule nucleation; [PTHR19302:SF14] GAMMA-TUBULIN COMPLEX COMPONENT 3 (GCP-3) 42.14 0.7681 53 Mapoly0039s0094 [PTHR15856] PHD FINGER PROTEIN 20-RELATED; [KOG1844] PHD Zn-finger proteins 42.83 0.7607 54 Mapoly0080s0056 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K10738] minichromosome maintenance protein 9; [PTHR11630:SF48] DNA REPLICATION LICENSING FACTOR MCM1; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [KOG0477] DNA replication licensing factor, MCM2 component 45.06 0.7527 55 Mapoly0026s0077 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [2.7.11.1] Non-specific serine/threonine protein kinase.; [PF08064] UME (NUC010) domain; [PF00454] Phosphatidylinositol 3- and 4-kinase; [K06640] ataxia telangiectasia and Rad3 related [EC:2.7.11.1]; [GO:0004674] protein serine/threonine kinase activity; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [KOG0890] Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination 45.30 0.7836 56 Mapoly0020s0135 [PF03941] Inner centromere protein, ARK binding region; [PTHR13142:SF1] INCENP; [KOG1295] Nonsense-mediated decay protein Upf3; [PTHR13142] INNER CENTROMERE PROTEIN 46.45 0.8280 57 Mapoly0005s0174 [GO:0005524] ATP binding; [KOG0933] Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E); [GO:0007076] mitotic chromosome condensation; [GO:0005515] protein binding; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0000796] condensin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PTHR18937:SF9] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC2; [K06674] structural maintenance of chromosome 2; [PF06470] SMC proteins Flexible Hinge Domain 46.50 0.8333 58 Mapoly0045s0061 [KOG1081] Transcription factor NSD1 and related SET domain proteins; [GO:0005515] protein binding; [PF00856] SET domain; [PTHR22884] SET DOMAIN PROTEINS 48.43 0.7915 59 Mapoly0081s0073 - 48.63 0.8105 60 Mapoly0019s0059 [PTHR31398:SF0] SUBFAMILY NOT NAMED; [PTHR31398] FAMILY NOT NAMED; [PF03962] Mnd1 family; [KOG3433] Protein involved in meiotic recombination/predicted coiled-coil protein 48.84 0.8019 61 Mapoly0001s0472 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED 48.96 0.8076 62 Mapoly0011s0202 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain 49.02 0.8273 63 Mapoly0102s0024 [GO:0006355] regulation of transcription, DNA-dependent; [PF14443] DBC1; [KOG3227] Calcium-responsive transcription coactivator; [PTHR14304] P30 DBC PROTEIN 52.38 0.8068 64 Mapoly0043s0056 [K12831] splicing factor 3B subunit 4; [KOG0131] Splicing factor 3b, subunit 4; [PTHR24011] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 53.10 0.7546 65 Mapoly0005s0061 [PF00089] Trypsin; [PTHR22939] SERINE PROTEASE FAMILY S1C HTRA-RELATED; [GO:0005515] protein binding; [PF13180] PDZ domain; [KOG1320] Serine protease; [GO:0004252] serine-type endopeptidase activity; [GO:0006508] proteolysis 54.25 0.7686 66 Mapoly0030s0102 [PF08317] Spc7 kinetochore protein 54.33 0.8130 67 Mapoly0009s0039 [GO:0030915] Smc5-Smc6 complex; [KOG2866] Uncharacterized conserved protein; [PTHR16140:SF0] SUBFAMILY NOT NAMED; [PTHR16140] UNCHARACTERIZED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08743] Nse4 C-terminal 54.54 0.8200 68 Mapoly0047s0105 [KOG4308] LRR-containing protein; [PTHR10098] RAPSYN-RELATED; [PF13516] Leucine Rich repeat; [PF13414] TPR repeat 55.39 0.8024 69 Mapoly0209s0008 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF67] DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 55.62 0.8203 70 Mapoly0002s0133 [GO:0007076] mitotic chromosome condensation; [PTHR13108] FAMILY NOT NAMED; [PF05786] Condensin complex subunit 2; [KOG2328] Chromosome condensation complex Condensin, subunit H; [GO:0000796] condensin complex; [K06676] condensin complex subunit 2 56.92 0.8080 71 Mapoly0070s0034 [KOG0108] mRNA cleavage and polyadenylation factor I complex, subunit RNA15; [PF14327] Hinge domain of cleavage stimulation factor subunit 2; [PTHR23139:SF8] RNA RECOGNITION MOTIF CONTAINING PROTEIN; [PTHR23139] RNA-BINDING PROTEIN; [GO:0003676] nucleic acid binding; [K14407] cleavage stimulation factor subunit 2; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 57.05 0.7744 72 Mapoly0147s0033 [PF07738] Sad1 / UNC-like C-terminal; [PTHR12911] SAD1/UNC-84-LIKE PROTEIN-RELATED; [KOG2687] Spindle pole body protein, contains UNC-84 domain 57.27 0.7797 73 Mapoly0001s0044 [PTHR31110] FAMILY NOT NAMED 57.69 0.7928 74 Mapoly0064s0053 [PTHR18950:SF0] SUBFAMILY NOT NAMED; [PTHR18950] PROGESTERONE-INDUCED BLOCKING FACTOR 1 59.60 0.7502 75 Mapoly0044s0021 [KOG0275] Conserved WD40 repeat-containing protein; [PTHR22848] WD40 REPEAT PROTEIN; [GO:0005515] protein binding; [K13111] WD40 repeat-containing protein SMU1; [PF00400] WD domain, G-beta repeat 60.30 0.7708 76 Mapoly0061s0078 [KOG1361] Predicted hydrolase involved in interstrand cross-link repair; [PTHR23240] DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; [PF12706] Beta-lactamase superfamily domain; [PF07522] DNA repair metallo-beta-lactamase; [PF00536] SAM domain (Sterile alpha motif) 60.45 0.7775 77 Mapoly0089s0012 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 61.19 0.7649 78 Mapoly0030s0101 [GO:0042393] histone binding; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [K11647] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-]; [KOG0386] Chromatin remodeling complex SWI/SNF, component SWI2 and related ATPases (DNA/RNA helicase superfamily); [PTHR10799:SF209] GLOBAL TRANSCRIPTION ACTIVATOR SNF2L2 (ATP-DEPENDENT HELICASE SMARCA2); [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [PF14619] Snf2-ATP coupling, chromatin remodelling complex 61.93 0.7922 79 Mapoly0102s0001 [K06228] fused [EC:2.7.11.1]; [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR22983:SF6] MAPK KINASE 2-RELATED; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [KOG0598] Ribosomal protein S6 kinase and related proteins; [PF13646] HEAT repeats 61.97 0.8069 80 Mapoly0087s0035 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [PTHR24115:SF105] SUBFAMILY NOT NAMED; [KOG0243] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 62.10 0.7600 81 Mapoly0117s0005 [K13109] IK cytokine; [PTHR12765] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [KOG2498] IK cytokine down-regulator of HLA class II; [PF07807] RED-like protein C-terminal region; [PTHR12765:SF5] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [GO:0005634] nucleus; [PF07808] RED-like protein N-terminal region 62.83 0.7742 82 Mapoly0001s0525 [K14408] cleavage stimulation factor subunit 3; [GO:0006397] mRNA processing; [GO:0005634] nucleus; [KOG1914] mRNA cleavage and polyadenylation factor I complex, subunit RNA14; [PTHR19980] RNA CLEAVAGE STIMULATION FACTOR; [PF05843] Suppressor of forked protein (Suf) 63.69 0.7818 83 Mapoly0125s0021 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR23273:SF0] SUBFAMILY NOT NAMED; [GO:0008270] zinc ion binding; [PF04057] Replication factor-A protein 1, N-terminal domain; [PF00098] Zinc knuckle; [GO:0005634] nucleus; [PF08646] Replication factor-A C terminal domain; [GO:0003676] nucleic acid binding; [K07466] replication factor A1; [PTHR23273] REPLICATION FACTOR A 1, RFA1; [PF01336] OB-fold nucleic acid binding domain 64.48 0.7291 84 Mapoly0116s0041 [PF13297] Telomere stability C-terminal; [PTHR12786:SF2] SPLICING FACTOR 3A; [PF12108] Splicing factor SF3a60 binding domain; [KOG2636] Splicing factor 3a, subunit 3; [PTHR12786] SPLICING FACTOR SF3A-RELATED; [K12827] splicing factor 3A subunit 3; [PF11931] Domain of unknown function (DUF3449) 64.81 0.7838 85 Mapoly0009s0225 [PTHR22942] RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER; [KOG1564] DNA repair protein RHP57; [PTHR22942:SF24] SUBFAMILY NOT NAMED; [K10880] DNA-repair protein XRCC3; [PF08423] Rad51 65.18 0.7647 86 Mapoly0043s0047 [GO:0005515] protein binding; [PF00612] IQ calmodulin-binding motif; [PTHR25069] FAMILY NOT NAMED; [PF00307] Calponin homology (CH) domain 66.33 0.8084 87 Mapoly0001s0362 - 66.87 0.7378 88 Mapoly0120s0004 [PF00488] MutS domain V; [GO:0005524] ATP binding; [K08735] DNA mismatch repair protein MSH2; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PTHR11361:SF35] MUTS HOMOLOG 2, MSH2; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III; [KOG0219] Mismatch repair ATPase MSH2 (MutS family); [PF05190] MutS family domain IV 67.19 0.7840 89 Mapoly0008s0208 [GO:0003755] peptidyl-prolyl cis-trans isomerase activity; [PTHR11071] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF00160] Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; [GO:0005515] protein binding; [GO:0000413] protein peptidyl-prolyl isomerization; [GO:0006457] protein folding; [K12736] peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8]; [5.2.1.8] Peptidylprolyl isomerase.; [KOG0882] Cyclophilin-related peptidyl-prolyl cis-trans isomerase; [PF00400] WD domain, G-beta repeat 67.45 0.7608 90 Mapoly0051s0060 [PTHR31399:SF0] SUBFAMILY NOT NAMED; [PF03121] Herpesviridae UL52/UL70 DNA primase; [GO:0006260] DNA replication; [GO:0003896] DNA primase activity; [PTHR31399] FAMILY NOT NAMED 69.20 0.7662 91 Mapoly0019s0032 - 69.42 0.7808 92 Mapoly0009s0067 [PTHR31789] FAMILY NOT NAMED 70.01 0.7610 93 Mapoly0030s0009 [PF00505] HMG (high mobility group) box; [KOG0526] Nucleosome-binding factor SPN, POB3 subunit; [PF03531] Structure-specific recognition protein (SSRP1); [PTHR13711:SF39] SUBFAMILY NOT NAMED; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [PF08512] Histone chaperone Rttp106-like; [K09272] structure-specific recognition protein 1 70.71 0.7709 94 Mapoly0137s0008 [PF06278] Protein of unknown function (DUF1032); [PTHR14324] FAMILY NOT NAMED; [PTHR14324:SF3] SUBFAMILY NOT NAMED; [K11490] condensin-2 complex subunit H2; [KOG2359] Uncharacterized conserved protein 71.73 0.7699 95 Mapoly0005s0208 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [KOG0244] Kinesin-like protein; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [K10395] kinesin family member 4/7/21/27; [GO:0003777] microtubule motor activity 72.44 0.7787 96 Mapoly0021s0143 - 72.73 0.7660 97 Mapoly0010s0152 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PTHR13561:SF5] DNA REPLICATION REGULATOR DPB11; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 72.85 0.7948 98 Mapoly0001s0557 [PTHR11142] PSEUDOURIDYLATE SYNTHASE; [GO:0003723] RNA binding; [K06173] tRNA pseudouridine synthase A [EC:5.4.99.12]; [GO:0001522] pseudouridine synthesis; [KOG2553] Pseudouridylate synthase; [GO:0009451] RNA modification; [PF01416] tRNA pseudouridine synthase; [GO:0009982] pseudouridine synthase activity; [5.4.99.12] tRNA pseudouridine(38-40) synthase. 72.89 0.7433 99 Mapoly0043s0112 [PTHR21780] UNCHARACTERIZED; [KOG4670] Uncharacterized conserved membrane protein; [PTHR21780:SF0] SUBFAMILY NOT NAMED; [PF09786] Cytochrome B561, N terminal 73.61 0.7943 100 Mapoly0108s0031 [GO:0005524] ATP binding; [K04499] RuvB-like protein 1 (pontin 52); [KOG1942] DNA helicase, TBP-interacting protein; [PF06068] TIP49 C-terminus; [GO:0043141] ATP-dependent 5'-3' DNA helicase activity; [GO:0003678] DNA helicase activity; [PTHR11093] RUVB-RELATED REPTIN AND PONTIN 74.22 0.7696 101 Mapoly0029s0028 [PF00249] Myb-like DNA-binding domain; [GO:0005515] protein binding; [PF00569] Zinc finger, ZZ type; [GO:0003682] chromatin binding; [GO:0008270] zinc ion binding; [PF04433] SWIRM domain; [PTHR12374] TRANSCRIPTIONAL ADAPTOR 2 (ADA2)-RELATED; [KOG0457] Histone acetyltransferase complex SAGA/ADA, subunit ADA2; [K11314] transcriptional adapter 2-alpha 75.37 0.7536 102 Mapoly0042s0047 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF65] DNA REPAIR AND RECOMBINATION PROTEIN RAD26-RELATED 77.00 0.7632 103 Mapoly0082s0082 - 77.14 0.7356 104 Mapoly0003s0057 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination 77.29 0.7975 105 Mapoly0050s0019 [PF08642] Histone deacetylation protein Rxt3; [KOG4843] Uncharacterized conserved protein 77.81 0.7368 106 Mapoly0045s0096 [K08775] breast cancer 2 susceptibility protein; [PTHR11289] BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2; [GO:0003697] single-stranded DNA binding; [PF09169] BRCA2, helical; [PTHR11289:SF0] SUBFAMILY NOT NAMED; [GO:0006281] DNA repair; [PF09103] BRCA2, oligonucleotide/oligosaccharide-binding, domain 1; [GO:0000724] double-strand break repair via homologous recombination; [GO:0006310] DNA recombination 77.92 0.6971 107 Mapoly0087s0011 [GO:0005634] nucleus; [PF07557] Shugoshin C terminus; [GO:0000775] chromosome, centromeric region; [GO:0045132] meiotic chromosome segregation 78.10 0.7696 108 Mapoly0015s0045 [KOG0533] RRM motif-containing protein; [PTHR19965] RNA AND EXPORT FACTOR BINDING PROTEIN; [K12881] THO complex subunit 4; [PF13865] C-terminal duplication domain of Friend of PRMT1; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 78.49 0.7547 109 Mapoly0023s0143 [GO:0005524] ATP binding; [PTHR23073] 26S PROTEASE REGULATORY SUBUNIT; [PTHR23073:SF18] SUBFAMILY NOT NAMED; [PF00004] ATPase family associated with various cellular activities (AAA) 78.51 0.7755 110 Mapoly0063s0076 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF0] CELL DIVISION PROTEIN KINASE 7; [K02202] cyclin-dependent kinase 7 [EC:2.7.11.22]; [KOG0659] Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 79.73 0.7423 111 Mapoly0062s0008 [PF02295] Adenosine deaminase z-alpha domain; [GO:0003723] RNA binding; [GO:0003726] double-stranded RNA adenosine deaminase activity 80.31 0.7171 112 Mapoly0032s0119 [GO:0007076] mitotic chromosome condensation; [K06678] condensin complex subunit 3; [GO:0000796] condensin complex; [PTHR14418] CONDENSIN COMPLEX SUBUNIT 3-RELATED; [PF12719] Nuclear condensing complex subunits, C-term domain 80.50 0.8016 113 Mapoly0042s0123 [K12875] apoptotic chromatin condensation inducer in the nucleus; [GO:0003676] nucleic acid binding; [PTHR14127] APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; [PF02037] SAP domain 81.26 0.7866 114 Mapoly0188s0017 [KOG4205] RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1; [PTHR24011] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 83.04 0.7241 115 Mapoly0004s0169 [GO:0003677] DNA binding; [GO:0006338] chromatin remodeling; [GO:0005524] ATP binding; [PF09110] HAND; [K11654] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]; [GO:0043044] ATP-dependent chromatin remodeling; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [GO:0005634] nucleus; [PTHR10799:SF73] ISWI CHROMATIN-REMODELING COMPLEX ATPASE ISW1; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [KOG0385] Chromatin remodeling complex WSTF-ISWI, small subunit; [GO:0003676] nucleic acid binding; [GO:0031491] nucleosome binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [PF09111] SLIDE 84.50 0.7778 116 Mapoly0140s0032 [PTHR12748] ORIGIN RECOGNITION COMPLEX SUBUNIT 3; [PTHR12748:SF0] SUBFAMILY NOT NAMED; [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02605] origin recognition complex subunit 3; [PF07034] Origin recognition complex (ORC) subunit 3 N-terminus; [KOG2538] Origin recognition complex, subunit 3; [GO:0005664] nuclear origin of replication recognition complex; [PF02178] AT hook motif 85.90 0.7946 117 Mapoly0034s0119 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 85.98 0.8007 118 Mapoly0002s0125 [PTHR25040] FAMILY NOT NAMED; [PF11926] Domain of unknown function (DUF3444); [PTHR25040:SF79] SUBFAMILY NOT NAMED; [PF00226] DnaJ domain 86.14 0.7885 119 Mapoly0004s0202 - 86.30 0.7718 120 Mapoly0074s0003 [GO:0003677] DNA binding; [PF12254] DNA polymerase alpha subunit p180 N terminal; [GO:0006260] DNA replication; [GO:0001882] nucleoside binding; [K02320] DNA polymerase alpha subunit A [EC:2.7.7.7]; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0006270] DNA replication initiation; [PF08996] DNA Polymerase alpha zinc finger; [KOG0970] DNA polymerase alpha, catalytic subunit; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT 87.29 0.7617 121 Mapoly0092s0032 [PTHR22597] POLYCOMB GROUP PROTEIN; [PTHR22597:SF0] SUBFAMILY NOT NAMED; [PF09733] VEFS-Box of polycomb protein 87.54 0.7722 122 Mapoly0015s0126 [GO:0008641] small protein activating enzyme activity; [GO:0005524] ATP binding; [K10685] ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19]; [KOG2013] SMT3/SUMO-activating complex, catalytic component UBA2; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [PF14732] Ubiquitin/SUMO-activating enzyme ubiquitin-like domain 87.67 0.7630 123 Mapoly0069s0001 [GO:0016020] membrane; [KOG2301] Voltage-gated Ca2+ channels, alpha1 subunits; [PTHR10037] VOLTAGE-GATED CATION CHANNEL (CALCIUM AND SODIUM); [PF00520] Ion transport protein; [GO:0055085] transmembrane transport; [K04857] voltage-dependent calcium channel L type alpha-1S; [GO:0006811] ion transport; [GO:0005216] ion channel activity 87.80 0.7405 124 Mapoly0032s0034 - 88.94 0.7662 125 Mapoly0097s0064 [PTHR13710:SF1] ROTHMUND-THOMSON SYNDROME DNA HELICASE RECQ4; [GO:0005524] ATP binding; [PF11719] DNA replication and checkpoint protein; [K10730] ATP-dependent DNA helicase Q4 [EC:3.6.4.12]; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [GO:0003676] nucleic acid binding; [PF02037] SAP domain 89.80 0.7853 126 Mapoly0013s0077 [PTHR24413] FAMILY NOT NAMED; [PF00651] BTB/POZ domain; [GO:0005515] protein binding 90.66 0.6150 127 Mapoly0045s0033 [PTHR16199] FAMILY NOT NAMED; [K11492] condensin-2 complex subunit G2; [GO:0005634] nucleus; [PF12422] Condensin II non structural maintenance of chromosomes subunit 91.49 0.6949 128 Mapoly0029s0120 [PF05178] KRI1-like family; [KOG2409] KRR1-interacting protein involved in 40S ribosome biogenesis; [PTHR14490] ZINC FINGER, ZZ TYPE; [PF12936] KRI1-like family C-terminal 91.80 0.7246 129 Mapoly0001s0446 - 93.58 0.7569 130 Mapoly0007s0100 [PTHR15828] CYTOKINE RECEPTOR-LIKE FACTOR 3 94.23 0.7634 131 Mapoly0033s0098 [PTHR16047] RFWD3 PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PTHR16047:SF7] RFWD3 PROTEIN-RELATED; [KOG1645] RING-finger-containing E3 ubiquitin ligase 94.66 0.7613 132 Mapoly0043s0081 [GO:0005524] ATP binding; [PF02889] Sec63 Brl domain; [PTHR11752] HELICASE SKI2W; [3.6.4.13] RNA helicase.; [PF00270] DEAD/DEAH box helicase; [PTHR11752:SF7] U520; [PF00271] Helicase conserved C-terminal domain; [KOG0951] RNA helicase BRR2, DEAD-box superfamily; [GO:0003676] nucleic acid binding; [K12854] pre-mRNA-splicing helicase BRR2 [EC:3.6.4.13] 95.34 0.7501 133 Mapoly0045s0042 [KOG2475] CDC45 (cell division cycle 45)-like protein; [GO:0006270] DNA replication initiation; [PF02724] CDC45-like protein; [PTHR10507:SF0] CDC45-RELATED PROTEIN; [PTHR10507] CDC45-RELATED PROTEIN; [K06628] cell division control protein 45 95.91 0.7850 134 Mapoly0001s0188 - 96.09 0.7796 135 Mapoly0002s0324 [GO:0005524] ATP binding; [GO:0016021] integral to membrane; [PTHR24223] FAMILY NOT NAMED; [PF00664] ABC transporter transmembrane region; [GO:0016887] ATPase activity; [GO:0006810] transport; [GO:0055085] transmembrane transport; [KOG0054] Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily; [GO:0042626] ATPase activity, coupled to transmembrane movement of substances; [PF00005] ABC transporter 98.12 0.6770 136 Mapoly0118s0005 [GO:0008233] peptidase activity; [3.4.22.49] Separase.; [K02365] separase [EC:3.4.22.49]; [GO:0005634] nucleus; [PF03568] Peptidase family C50; [GO:0006508] proteolysis; [PTHR12792] EXTRA SPINDLE POLES 1-RELATED 98.29 0.7786 137 Mapoly0036s0107 [K09422] myb proto-oncogene protein, plant; [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding; [PF13921] Myb-like DNA-binding domain 98.87 0.7705 138 Mapoly0001s0432 [PF08553] VID27 cytoplasmic protein; [PTHR31913] FAMILY NOT NAMED; [KOG2395] Protein involved in vacuole import and degradation 99.02 0.6237 139 Mapoly0076s0033 [PF10444] Nbl1 / Borealin N terminal 99.38 0.7786 140 Mapoly0016s0130 [PF14817] HAUS augmin-like complex subunit 5; [GO:0051225] spindle assembly 99.84 0.7668 141 Mapoly0051s0002 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 99.84 0.7774 142 Mapoly0072s0051 [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [KOG0597] Serine-threonine protein kinase FUSED; [GO:0006468] protein phosphorylation 102.30 0.7757 143 Mapoly0082s0057 [PTHR32282] FAMILY NOT NAMED; [PF00912] Transglycosylase; [PTHR32282:SF0] SUBFAMILY NOT NAMED; [PF00905] Penicillin binding protein transpeptidase domain; [GO:0008658] penicillin binding 102.85 0.6978 144 Mapoly0130s0037 [GO:0016020] membrane; [GO:0006486] protein glycosylation; [KOG2292] Oligosaccharyltransferase, STT3 subunit; [2.4.1.119] Transferred entry: 2.4.99.18.; [PTHR13872] 60S RIBOSOMAL PROTEIN L35; [K07151] dolichyl-diphosphooligosaccharide--protein glycosyltransferase [EC:2.4.1.119]; [PTHR13872:SF1] OLIGOSACCHARYL TRANSFERASE; [PF02516] Oligosaccharyl transferase STT3 subunit; [GO:0004576] oligosaccharyl transferase activity 104.12 0.6921 145 Mapoly0226s0007 [PF00817] impB/mucB/samB family; [2.7.7.7] DNA-directed DNA polymerase.; [GO:0006281] DNA repair; [PF11799] impB/mucB/samB family C-terminal domain; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [PTHR11076:SF11] DNA POLYMERASE ETA; [GO:0003887] DNA-directed DNA polymerase activity; [GO:0003684] damaged DNA binding; [K03509] DNA polymerase eta subunit [EC:2.7.7.7] 104.16 0.6834 146 Mapoly0033s0145 - 107.67 0.7617 147 Mapoly0035s0137 [GO:0005643] nuclear pore; [PTHR10350:SF6] NUCLEOPORIN 155; [PF03177] Non-repetitive/WGA-negative nucleoporin C-terminal; [K14312] nuclear pore complex protein Nup155; [KOG1900] Nuclear pore complex, Nup155 component (D Nup154, sc Nup157/Nup170); [GO:0006913] nucleocytoplasmic transport; [PF08801] Nup133 N terminal like; [GO:0017056] structural constituent of nuclear pore; [PTHR10350] NUCLEAR PORE COMPLEX PROTEIN NUP155 109.00 0.7714 148 Mapoly0099s0028 [GO:0005524] ATP binding; [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family; [KOG0360] Chaperonin complex component, TCP-1 alpha subunit (CCT1) 109.11 0.7294 149 Mapoly0060s0056 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 109.60 0.7531 150 Mapoly0118s0038 - 110.66 0.7451 151 Mapoly0085s0026 [PF00533] BRCA1 C Terminus (BRCT) domain; [PTHR23196] PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN 110.70 0.7735 152 Mapoly0108s0041 [PTHR14978:SF0] SUBFAMILY NOT NAMED; [PTHR14978] BETA-CATENIN-LIKE PROTEIN 1 (NUCLEAR ASSOCIATED PROTEIN); [K12864] beta-catenin-like protein 1; [KOG2734] Uncharacterized conserved protein; [PF08216] Catenin-beta-like, Arm-motif containing nuclear 110.85 0.7273 153 Mapoly0003s0084 - 111.62 0.6705 154 Mapoly0030s0020 [KOG2545] Conserved membrane protein; [PTHR13489:SF0] SUBFAMILY NOT NAMED; [PF13615] Putative alanine racemase; [PF09739] Mini-chromosome maintenance replisome factor; [PTHR13489] UNCHARACTERIZED 112.05 0.7776 155 Mapoly0030s0095 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [K10405] kinesin family member C1; [GO:0003777] microtubule motor activity 112.41 0.7430 156 Mapoly0165s0024 [GO:0006338] chromatin remodeling; [GO:0043968] histone H2A acetylation; [PF00249] Myb-like DNA-binding domain; [K11324] DNA methyltransferase 1-associated protein 1; [GO:0043967] histone H4 acetylation; [KOG2656] DNA methyltransferase 1-associated protein-1; [GO:0003682] chromatin binding; [PTHR12855] FAMILY NOT NAMED; [GO:0035267] NuA4 histone acetyltransferase complex; [GO:0006281] DNA repair; [PTHR12855:SF10] SUBFAMILY NOT NAMED 113.13 0.7443 157 Mapoly0055s0064 - 114.26 0.7734 158 Mapoly0013s0040 [GO:0005524] ATP binding; [KOG0359] Chaperonin complex component, TCP-1 zeta subunit (CCT6); [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family 114.89 0.7402 159 Mapoly0005s0221 [GO:0005643] nuclear pore; [PTHR12084] NUCLEAR PORE GLYCOPROTEIN P62-RELATED; [KOG2196] Nuclear porin; [PTHR12084:SF0] SUBFAMILY NOT NAMED; [K14306] nuclear pore complex protein Nup62; [PF05064] Nsp1-like C-terminal region; [GO:0017056] structural constituent of nuclear pore 115.08 0.7468 160 Mapoly0027s0148 [PTHR22536] LUNG CANCER METASTASIS-RELATED (LCMR1) PROTEIN 115.59 0.6974 161 Mapoly0108s0040 [PF08167] rRNA processing/ribosome biogenesis 115.84 0.7685 162 Mapoly0069s0083 [K11662] actin-related protein 6; [PF00022] Actin; [PTHR11937:SF21] ACTIN-LIKE PROTEIN; [PTHR11937] ACTIN; [KOG0680] Actin-related protein - Arp6p 117.81 0.6725 163 Mapoly0098s0032 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [PF11721] Di-glucose binding within endoplasmic reticulum; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 118.11 0.7769 164 Mapoly0001s0170 - 118.49 0.7336 165 Mapoly0009s0019 [KOG1898] Splicing factor 3b, subunit 3; [PTHR10644:SF1] SPLICING FACTOR 3B SUBUNIT 3 (SPLICEOSOME-ASSOCIATED PROTEIN 130)(SAP 130); [PF10433] Mono-functional DNA-alkylating methyl methanesulfonate N-term; [PF03178] CPSF A subunit region; [GO:0005634] nucleus; [PTHR10644] DNA REPAIR/RNA PROCESSING CPSF FAMILY; [GO:0003676] nucleic acid binding; [K12830] splicing factor 3B subunit 3 118.93 0.7630 166 Mapoly0062s0038 - 119.70 0.6039 167 Mapoly0113s0034 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PF01698] Floricaula / Leafy protein 120.09 0.7194 168 Mapoly0005s0044 [K14321] nucleoporin-like protein 2; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 120.33 0.6690 169 Mapoly0053s0106 - 121.36 0.7705 170 Mapoly0037s0121 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) 121.52 0.7195 171 Mapoly0068s0001 [K10736] minichromosome maintenance protein 10; [GO:0006260] DNA replication; [PTHR13454] FAMILY NOT NAMED; [PF09329] Primase zinc finger; [GO:0005634] nucleus 121.96 0.7596 172 Mapoly0147s0014 [PTHR14790] FAMILY NOT NAMED; [PF08585] Domain of unknown function (DUF1767) 122.28 0.7349 173 Mapoly0035s0035 [PTHR11132] SOLUTE CARRIER FAMILY 35; [KOG1443] Predicted integral membrane protein 122.52 0.6502 174 Mapoly0001s0076 [PF00225] Kinesin motor domain; [GO:0007018] microtubule-based movement; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0008017] microtubule binding; [KOG4280] Kinesin-like protein; [PF06548] Kinesin-related; [GO:0003777] microtubule motor activity; [GO:0005871] kinesin complex 123.74 0.7657 175 Mapoly0002s0134 [GO:0005524] ATP binding; [GO:0006165] nucleoside diphosphate phosphorylation; [GO:0004550] nucleoside diphosphate kinase activity; [PF00334] Nucleoside diphosphate kinase; [K00940] nucleoside-diphosphate kinase [EC:2.7.4.6]; [PTHR11349] NUCLEOSIDE DIPHOSPHATE KINASE; [GO:0006241] CTP biosynthetic process; [GO:0006228] UTP biosynthetic process; [KOG0888] Nucleoside diphosphate kinase; [2.7.4.6] Nucleoside-diphosphate kinase.; [GO:0006183] GTP biosynthetic process 125.52 0.7219 176 Mapoly0003s0063 [GO:0005524] ATP binding; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24361:SF129] MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE; [GO:0006468] protein phosphorylation; [PTHR24361] MITOGEN-ACTIVATED KINASE KINASE KINASE 125.67 0.7697 177 Mapoly0073s0079 [GO:0046907] intracellular transport; [GO:0005643] nuclear pore; [PTHR23138] RAN BINDING PROTEIN; [PTHR23138:SF46] ABR034WP; [PF00638] RanBP1 domain; [PF08911] NUP50 (Nucleoporin 50 kDa) 125.74 0.7382 178 Mapoly0158s0032 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [K10728] topoisomerase (DNA) II binding protein 1; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 126.67 0.7131 179 Mapoly0057s0017 - 126.75 0.7594 180 Mapoly0012s0180 [PTHR15572] GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1; [PF15249] Glioma tumor suppressor candidate region 127.07 0.7198 181 Mapoly0027s0013 [KOG4487] Uncharacterized conserved protein; [PF09696] Ctf8; [K11270] chromosome transmission fidelity protein 8 129.07 0.7643 182 Mapoly0002s0004 [KOG1189] Global transcriptional regulator, cell division control protein; [PF00557] Metallopeptidase family M24; [PF08512] Histone chaperone Rttp106-like; [PTHR13980] CDC68 RELATED; [PF08644] FACT complex subunit (SPT16/CDC68) 129.16 0.7027 183 Mapoly0002s0297 [PTHR11731] PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; [KOG2100] Dipeptidyl aminopeptidase; [GO:0008236] serine-type peptidase activity; [PF07676] WD40-like Beta Propeller Repeat; [GO:0006508] proteolysis; [PF00326] Prolyl oligopeptidase family 129.31 0.7160 184 Mapoly0051s0075 [GO:0003723] RNA binding; [KOG2190] PolyC-binding proteins alphaCP-1 and related KH domain proteins; [PTHR10288] KH DOMAIN CONTAINING RNA BINDING PROTEIN; [PTHR10288:SF102] ANKYRIN REPEAT-CONTAINING PROTEIN; [PF00013] KH domain 129.61 0.6864 185 Mapoly0039s0109 [KOG0553] TPR repeat-containing protein; [PF14559] Tetratricopeptide repeat; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR 130.45 0.7294 186 Mapoly0008s0250 [PTHR24007] BRCA1-ASSOCIATED PROTEIN; [PF00917] MATH domain; [GO:0005515] protein binding; [GO:0006281] DNA repair; [PF14631] Fanconi anaemia protein FancD2 nuclease; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 130.80 0.7292 187 Mapoly0023s0117 [PTHR10139] DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11A; [PF04152] Mre11 DNA-binding presumed domain; [KOG2310] DNA repair exonuclease MRE11; [GO:0006259] DNA metabolic process; [PF00149] Calcineurin-like phosphoesterase; [GO:0006302] double-strand break repair; [GO:0016787] hydrolase activity; [GO:0030145] manganese ion binding; [GO:0005634] nucleus; [GO:0004527] exonuclease activity; [K10865] double-strand break repair protein MRE11; [GO:0004519] endonuclease activity 131.77 0.7347 188 Mapoly0064s0110 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR13394] ORIGIN RECOGNITION COMPLEX SUBUNIT 6; [PF05460] Origin recognition complex subunit 6 (ORC6); [GO:0005664] nuclear origin of replication recognition complex; [K02608] origin recognition complex subunit 6; [PTHR13394:SF0] SUBFAMILY NOT NAMED; [KOG4557] Origin recognition complex, subunit 6 133.63 0.7628 189 Mapoly0025s0127 - 133.79 0.7477 190 Mapoly0098s0012 [PTHR23147] SERINE/ARGININE RICH SPLICING FACTOR; [KOG0126] Predicted RNA-binding protein (RRM superfamily); [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 134.24 0.6967 191 Mapoly0006s0154 - 134.44 0.7054 192 Mapoly0101s0048 [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat 136.00 0.7588 193 Mapoly0173s0011 [PF00183] Hsp90 protein; [GO:0005524] ATP binding; [GO:0006950] response to stress; [KOG0020] Endoplasmic reticulum glucose-regulated protein (GRP94/endoplasmin), HSP90 family; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [GO:0006457] protein folding; [K04079] molecular chaperone HtpG; [PTHR11528] HEAT SHOCK PROTEIN 90; [GO:0051082] unfolded protein binding 136.76 0.7397 194 Mapoly0052s0054 [KOG0362] Chaperonin complex component, TCP-1 theta subunit (CCT8); [GO:0005524] ATP binding; [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family 137.00 0.6927 195 Mapoly0041s0127 [KOG0286] G-protein beta subunit; [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [PF00400] WD domain, G-beta repeat 137.94 0.6959 196 Mapoly0159s0029 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [PTHR12081:SF7] TRANSCRIPTION FACTOR E2F; [PTHR12081] TRANSCRIPTION FACTOR E2F 137.99 0.7142 197 Mapoly0074s0043 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [GO:0003729] mRNA binding 138.77 0.7398 198 Mapoly0019s0115 [PTHR23002] ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN; [PF14392] Zinc knuckle; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding 139.08 0.7029 199 Mapoly0094s0016 [KOG4674] Uncharacterized conserved coiled-coil protein 139.35 0.7524 200 Mapoly0065s0078 [PTHR24115:SF171] SUBFAMILY NOT NAMED; [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [K10403] kinesin family member 22; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 139.49 0.7572