Guide Gene
- Gene ID
- Mapoly0042s0023
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [GO:0005524] ATP binding; [2.7.12.1] Dual-specificity kinase.; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [K08866] serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]; [PTHR22974] MIXED LINEAGE PROTEIN KINASE
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0042s0023 [GO:0005524] ATP binding; [2.7.12.1] Dual-specificity kinase.; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [K08866] serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]; [PTHR22974] MIXED LINEAGE PROTEIN KINASE 0.00 1.0000 1 Mapoly0072s0051 [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [KOG0597] Serine-threonine protein kinase FUSED; [GO:0006468] protein phosphorylation 1.41 0.9258 2 Mapoly0001s0188 - 4.90 0.9233 3 Mapoly0061s0044 [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2) 6.00 0.9092 4 Mapoly0033s0057 [2.3.1.-] Transferring groups other than amino-acyl groups.; [PTHR11076:SF1] ESTABLISHMENT OF COHESION 1 (ECO1) HOMOLOG; [PF13880] ESCO1/2 acetyl-transferase; [PF13878] zinc-finger of acetyl-transferase ESCO; [KOG3014] Protein involved in establishing cohesion between sister chromatids during DNA replication; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [K11268] N-acetyltransferase [EC:2.3.1.-] 6.63 0.8996 5 Mapoly0118s0005 [GO:0008233] peptidase activity; [3.4.22.49] Separase.; [K02365] separase [EC:3.4.22.49]; [GO:0005634] nucleus; [PF03568] Peptidase family C50; [GO:0006508] proteolysis; [PTHR12792] EXTRA SPINDLE POLES 1-RELATED 6.71 0.9099 6 Mapoly0020s0135 [PF03941] Inner centromere protein, ARK binding region; [PTHR13142:SF1] INCENP; [KOG1295] Nonsense-mediated decay protein Upf3; [PTHR13142] INNER CENTROMERE PROTEIN 7.35 0.9156 7 Mapoly0101s0065 [PF12330] Domain of unknown function (DUF3635); [PTHR24419] INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE; [KOG2464] Serine/threonine kinase (haspin family) 7.62 0.8336 8 Mapoly0043s0047 [GO:0005515] protein binding; [PF00612] IQ calmodulin-binding motif; [PTHR25069] FAMILY NOT NAMED; [PF00307] Calponin homology (CH) domain 8.72 0.9137 9 Mapoly0047s0105 [KOG4308] LRR-containing protein; [PTHR10098] RAPSYN-RELATED; [PF13516] Leucine Rich repeat; [PF13414] TPR repeat 9.17 0.8942 10 Mapoly0102s0001 [K06228] fused [EC:2.7.11.1]; [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR22983:SF6] MAPK KINASE 2-RELATED; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [KOG0598] Ribosomal protein S6 kinase and related proteins; [PF13646] HEAT repeats 9.95 0.9037 11 Mapoly0070s0053 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF09382] RQC domain; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [K10901] bloom syndrome protein [EC:3.6.4.12]; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 10.39 0.8542 12 Mapoly0004s0300 [GO:0005524] ATP binding; [PTHR11909:SF7] CELL DIVISION CONTROL PROTEIN 7; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K02214] cell division control protein 7 [EC:2.7.11.1]; [KOG1167] Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination; [GO:0006468] protein phosphorylation; [PTHR11909] CASEIN KINASE-RELATED 11.96 0.8966 13 Mapoly0004s0250 [GO:0005643] nuclear pore; [PF07817] GLE1-like protein; [GO:0016973] poly(A)+ mRNA export from nucleus; [KOG2412] Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor; [PTHR12960:SF0] SUBFAMILY NOT NAMED; [PTHR12960] GLE-1-RELATED 12.49 0.8382 14 Mapoly0001s0076 [PF00225] Kinesin motor domain; [GO:0007018] microtubule-based movement; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0008017] microtubule binding; [KOG4280] Kinesin-like protein; [PF06548] Kinesin-related; [GO:0003777] microtubule motor activity; [GO:0005871] kinesin complex 12.69 0.9092 15 Mapoly0005s0174 [GO:0005524] ATP binding; [KOG0933] Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E); [GO:0007076] mitotic chromosome condensation; [GO:0005515] protein binding; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0000796] condensin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PTHR18937:SF9] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC2; [K06674] structural maintenance of chromosome 2; [PF06470] SMC proteins Flexible Hinge Domain 13.56 0.9073 16 Mapoly0033s0145 - 13.96 0.8940 17 Mapoly0010s0152 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PTHR13561:SF5] DNA REPLICATION REGULATOR DPB11; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 14.07 0.8882 18 Mapoly0080s0001 [GO:0005515] protein binding; [PTHR15271] CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; [KOG1009] Chromatin assembly complex 1 subunit B/CAC2 (contains WD40 repeats); [K10751] chromatin assembly factor 1 subunit B; [PF00400] WD domain, G-beta repeat 14.07 0.8794 19 Mapoly0098s0032 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [PF11721] Di-glucose binding within endoplasmic reticulum; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 14.49 0.9003 20 Mapoly0023s0143 [GO:0005524] ATP binding; [PTHR23073] 26S PROTEASE REGULATORY SUBUNIT; [PTHR23073:SF18] SUBFAMILY NOT NAMED; [PF00004] ATPase family associated with various cellular activities (AAA) 15.33 0.8412 21 Mapoly0039s0109 [KOG0553] TPR repeat-containing protein; [PF14559] Tetratricopeptide repeat; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR 17.61 0.8654 22 Mapoly0011s0202 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain 18.44 0.8890 23 Mapoly0209s0008 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF67] DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 18.76 0.8907 24 Mapoly0003s0015 - 18.87 0.7368 25 Mapoly0097s0064 [PTHR13710:SF1] ROTHMUND-THOMSON SYNDROME DNA HELICASE RECQ4; [GO:0005524] ATP binding; [PF11719] DNA replication and checkpoint protein; [K10730] ATP-dependent DNA helicase Q4 [EC:3.6.4.12]; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [GO:0003676] nucleic acid binding; [PF02037] SAP domain 19.08 0.8717 26 Mapoly0034s0119 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 19.29 0.8995 27 Mapoly0010s0026 [GO:0006357] regulation of transcription from RNA polymerase II promoter; [PTHR13114] TRANSCRIPTIONAL CO-ACTIVATOR CRSP77-RELATED; [PF10156] Subunit 17 of Mediator complex; [GO:0001104] RNA polymerase II transcription cofactor activity; [GO:0016592] mediator complex 19.85 0.7257 28 Mapoly0211s0017 [PTHR32387] FAMILY NOT NAMED 20.35 0.7207 29 Mapoly0113s0048 [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [KOG1408] WD40 repeat protein; [PF00400] WD domain, G-beta repeat 23.81 0.8834 30 Mapoly0082s0057 [PTHR32282] FAMILY NOT NAMED; [PF00912] Transglycosylase; [PTHR32282:SF0] SUBFAMILY NOT NAMED; [PF00905] Penicillin binding protein transpeptidase domain; [GO:0008658] penicillin binding 24.82 0.7588 31 Mapoly0094s0016 [KOG4674] Uncharacterized conserved coiled-coil protein 25.30 0.8861 32 Mapoly0081s0073 - 25.38 0.8700 33 Mapoly0001s0044 [PTHR31110] FAMILY NOT NAMED 25.69 0.8370 34 Mapoly0022s0167 [PF12717] non-SMC mitotic condensation complex subunit 1; [PF12922] non-SMC mitotic condensation complex subunit 1, N-term; [GO:0007076] mitotic chromosome condensation; [PTHR14222] CONDENSIN; [KOG0414] Chromosome condensation complex Condensin, subunit D2; [K06677] condensin complex subunit 1 25.79 0.8871 35 Mapoly0060s0110 [PF15072] Domain of unknown function (DUF4539); [PTHR14523] FAMILY NOT NAMED; [PTHR14523:SF1] SUBFAMILY NOT NAMED 26.46 0.8403 36 Mapoly0061s0085 [PF14868] Domain of unknown function (DUF4487) 26.53 0.8447 37 Mapoly0043s0112 [PTHR21780] UNCHARACTERIZED; [KOG4670] Uncharacterized conserved membrane protein; [PTHR21780:SF0] SUBFAMILY NOT NAMED; [PF09786] Cytochrome B561, N terminal 27.50 0.8450 38 Mapoly0016s0083 [PF12214] Cell cycle regulated microtubule associated protein; [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [PTHR14326:SF9] TARGETING PROTEIN FOR XKLP2; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2) 28.28 0.8743 39 Mapoly0047s0034 [PTHR31636] FAMILY NOT NAMED; [PF03514] GRAS domain family 28.30 0.7982 40 Mapoly0105s0040 [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [GO:0005516] calmodulin binding; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2); [PF07839] Plant calmodulin-binding domain 28.93 0.8701 41 Mapoly0011s0047 [PTHR12972] DOWNSTREAM NEIGHBOR OF SON 29.48 0.8067 42 Mapoly0060s0012 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [K11498] centromeric protein E; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 30.20 0.8758 43 Mapoly0005s0208 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [KOG0244] Kinesin-like protein; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [K10395] kinesin family member 4/7/21/27; [GO:0003777] microtubule motor activity 30.85 0.8368 44 Mapoly0078s0037 [KOG0987] DNA helicase PIF1/RRM3; [PF05970] PIF1-like helicase; [GO:0006281] DNA repair; [PTHR23274] DNA HELICASE-RELATED; [GO:0003678] DNA helicase activity; [GO:0000723] telomere maintenance 31.62 0.7929 45 Mapoly0076s0085 [KOG0005] Ubiquitin-like protein; [GO:0005515] protein binding; [PF00240] Ubiquitin family; [PTHR10666:SF57] UBIQUITIN / RIBOSOMAL PROTEIN S27A.1 (PUTATIVE UNCHARACTERIZED PROTEIN) (OS01G03; [PTHR10666] UBIQUITIN 32.45 0.8478 46 Mapoly0051s0002 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 33.20 0.8676 47 Mapoly0043s0044 [PTHR13257:SF0] SUBFAMILY NOT NAMED; [K14318] nuclear pore complex protein Nup88; [PF10168] Nuclear pore component; [KOG4460] Nuclear pore complex, Nup88/rNup84 component; [PTHR13257] NUCLEOPORIN NUP84-RELATED 33.47 0.8047 48 Mapoly0042s0105 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 33.87 0.8535 49 Mapoly0091s0056 [PF05918] Apoptosis inhibitory protein 5 (API5); [KOG2213] Apoptosis inhibitor 5/fibroblast growth factor 2-interacting factor 2, and related proteins; [PTHR12758] APOPTOSIS INHIBITOR 5-RELATED 34.74 0.8107 50 Mapoly0003s0063 [GO:0005524] ATP binding; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24361:SF129] MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE; [GO:0006468] protein phosphorylation; [PTHR24361] MITOGEN-ACTIVATED KINASE KINASE KINASE 34.91 0.8782 51 Mapoly0015s0089 [GO:0005524] ATP binding; [KOG0335] ATP-dependent RNA helicase; [3.6.4.13] RNA helicase.; [K11594] ATP-dependent RNA helicase [EC:3.6.4.13]; [PF00270] DEAD/DEAH box helicase; [PTHR24031:SF9] HELICASE CONSERVED C-TERMINAL DOMAIN, PUTATIVE; [PF00271] Helicase conserved C-terminal domain; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding 34.94 0.7890 52 Mapoly0099s0038 [PF00564] PB1 domain; [GO:0005515] protein binding; [PTHR22904:SF22] GB DEF: HYPOTHETICAL PROTEIN; [PF13414] TPR repeat; [KOG4151] Myosin assembly protein/sexual cycle protein and related proteins; [PTHR22904] TPR REPEAT CONTAINING PROTEIN 35.28 0.8033 53 Mapoly0042s0049 - 35.41 0.8345 54 Mapoly0006s0290 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR10670:SF0] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A; [GO:0000166] nucleotide binding; [GO:0008270] zinc ion binding; [2.7.7.7] DNA-directed DNA polymerase.; [KOG1798] DNA polymerase epsilon, catalytic subunit A; [PF08490] Domain of unknown function (DUF1744); [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF00136] DNA polymerase family B; [GO:0008622] epsilon DNA polymerase complex; [K02324] DNA polymerase epsilon subunit 1 [EC:2.7.7.7]; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10670] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A 35.65 0.8453 55 Mapoly0030s0095 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [K10405] kinesin family member C1; [GO:0003777] microtubule motor activity 35.94 0.8075 56 Mapoly0098s0023 [PTHR19378] GOLGIN- RELATED; [PF14932] HAUS augmin-like complex subunit 3; [GO:0051225] spindle assembly; [GO:0070652] HAUS complex; [PTHR19378:SF0] SUBFAMILY NOT NAMED 36.28 0.7941 57 Mapoly0045s0042 [KOG2475] CDC45 (cell division cycle 45)-like protein; [GO:0006270] DNA replication initiation; [PF02724] CDC45-like protein; [PTHR10507:SF0] CDC45-RELATED PROTEIN; [PTHR10507] CDC45-RELATED PROTEIN; [K06628] cell division control protein 45 37.23 0.8555 58 Mapoly0030s0102 [PF08317] Spc7 kinetochore protein 37.50 0.8498 59 Mapoly0031s0090 [KOG0379] Kelch repeat-containing proteins; [PF13418] Galactose oxidase, central domain; [PTHR23244] KELCH REPEAT DOMAIN; [PF13415] Galactose oxidase, central domain 38.26 0.8312 60 Mapoly0041s0060 [GO:0003677] DNA binding; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PTHR13451:SF3] gb def: Hypothetical protein F6I18.220 (Hypothetical protein AT4g30870); [PF02732] ERCC4 domain 38.37 0.8264 61 Mapoly0085s0026 [PF00533] BRCA1 C Terminus (BRCT) domain; [PTHR23196] PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN 39.12 0.8668 62 Mapoly0159s0029 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [PTHR12081:SF7] TRANSCRIPTION FACTOR E2F; [PTHR12081] TRANSCRIPTION FACTOR E2F 39.40 0.7932 63 Mapoly0026s0077 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [2.7.11.1] Non-specific serine/threonine protein kinase.; [PF08064] UME (NUC010) domain; [PF00454] Phosphatidylinositol 3- and 4-kinase; [K06640] ataxia telangiectasia and Rad3 related [EC:2.7.11.1]; [GO:0004674] protein serine/threonine kinase activity; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [KOG0890] Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination 39.55 0.7965 64 Mapoly0032s0119 [GO:0007076] mitotic chromosome condensation; [K06678] condensin complex subunit 3; [GO:0000796] condensin complex; [PTHR14418] CONDENSIN COMPLEX SUBUNIT 3-RELATED; [PF12719] Nuclear condensing complex subunits, C-term domain 40.40 0.8633 65 Mapoly0036s0107 [K09422] myb proto-oncogene protein, plant; [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding; [PF13921] Myb-like DNA-binding domain 40.91 0.8300 66 Mapoly0025s0127 - 40.99 0.8454 67 Mapoly0006s0242 - 41.64 0.8547 68 Mapoly0130s0046 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF14493] Helix-turn-helix domain; [PF09382] RQC domain; [K10900] werner syndrome ATP-dependent helicase [EC:3.6.4.12]; [KOG0353] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 42.14 0.8089 69 Mapoly0006s0254 [PTHR13026:SF0] SUBFAMILY NOT NAMED; [PTHR13026] NNP-1 PROTEIN (NOVEL NUCLEAR PROTEIN 1) (NOP52); [GO:0030688] preribosome, small subunit precursor; [PF05997] Nucleolar protein,Nop52; [GO:0006364] rRNA processing 42.71 0.7844 70 Mapoly0019s0119 - 42.85 0.8390 71 Mapoly0023s0118 [PTHR12446] TESMIN/TSO1-RELATED; [PF03638] Tesmin/TSO1-like CXC domain, cysteine-rich domain 42.90 0.8441 72 Mapoly0087s0035 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [PTHR24115:SF105] SUBFAMILY NOT NAMED; [KOG0243] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 43.27 0.7820 73 Mapoly0167s0015 [KOG1076] Translation initiation factor 3, subunit c (eIF-3c); [K03252] translation initiation factor eIF-3 subunit 8; [PF05470] Eukaryotic translation initiation factor 3 subunit 8 N-terminus; [PTHR13937:SF0] SUBFAMILY NOT NAMED; [GO:0003743] translation initiation factor activity; [GO:0005515] protein binding; [PTHR13937] EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 (EIF3S8)-RELATED; [GO:0031369] translation initiation factor binding; [PF01399] PCI domain; [GO:0006413] translational initiation; [GO:0005852] eukaryotic translation initiation factor 3 complex 43.71 0.7630 74 Mapoly0053s0106 - 46.37 0.8449 75 Mapoly0037s0043 [PTHR24003] MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN-RELATED; [KOG4332] Predicted sugar transporter; [PF05631] Protein of unknown function (DUF791); [PTHR24003:SF368] SUBFAMILY NOT NAMED 46.88 0.6803 76 Mapoly0078s0012 [GO:0006396] RNA processing; [PTHR11061] RNA M5U METHYLTRANSFERASE FAMILY; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0008173] RNA methyltransferase activity; [PF05958] tRNA (Uracil-5-)-methyltransferase; [GO:0046872] metal ion binding; [KOG2187] tRNA uracil-5-methyltransferase and related tRNA-modifying enzymes 47.18 0.7897 77 Mapoly0034s0112 - 47.43 0.7972 78 Mapoly0024s0107 [PF07719] Tetratricopeptide repeat; [GO:0005515] protein binding; [PF13414] TPR repeat; [K03350] anaphase-promoting complex subunit 3; [KOG1126] DNA-binding cell division cycle control protein; [PF13181] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat; [PTHR12558] CELL DIVISION CYCLE 16,23,27; [PTHR12558:SF11] CELL DIVISION CYCLE 27; [PF12895] Anaphase-promoting complex, cyclosome, subunit 3 47.50 0.7685 79 Mapoly0060s0031 - 47.67 0.7678 80 Mapoly0103s0079 [GO:0003677] DNA binding; [PTHR13763:SF0] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0005634] nucleus; [GO:0006281] DNA repair; [GO:0004842] ubiquitin-protein ligase activity; [KOG4362] Transcriptional regulator BRCA1; [PTHR13763] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; [PF13771] PHD-like zinc-binding domain 49.14 0.8545 81 Mapoly0039s0061 [PF12612] Tubulin folding cofactor D C terminal; [KOG1943] Beta-tubulin folding cofactor D; [PTHR12658] BETA-TUBULIN COFACTOR D 52.10 0.7781 82 Mapoly0030s0020 [KOG2545] Conserved membrane protein; [PTHR13489:SF0] SUBFAMILY NOT NAMED; [PF13615] Putative alanine racemase; [PF09739] Mini-chromosome maintenance replisome factor; [PTHR13489] UNCHARACTERIZED 52.39 0.8445 83 Mapoly0035s0137 [GO:0005643] nuclear pore; [PTHR10350:SF6] NUCLEOPORIN 155; [PF03177] Non-repetitive/WGA-negative nucleoporin C-terminal; [K14312] nuclear pore complex protein Nup155; [KOG1900] Nuclear pore complex, Nup155 component (D Nup154, sc Nup157/Nup170); [GO:0006913] nucleocytoplasmic transport; [PF08801] Nup133 N terminal like; [GO:0017056] structural constituent of nuclear pore; [PTHR10350] NUCLEAR PORE COMPLEX PROTEIN NUP155 53.27 0.8235 84 Mapoly0009s0056 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PF08311] Mad3/BUB1 homology region 1; [K02178] checkpoint serine/threonine-protein kinase [EC:2.7.11.1]; [KOG1166] Mitotic checkpoint serine/threonine protein kinase; [PTHR14030] MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 55.56 0.8271 85 Mapoly0057s0017 - 55.86 0.8332 86 Mapoly0140s0032 [PTHR12748] ORIGIN RECOGNITION COMPLEX SUBUNIT 3; [PTHR12748:SF0] SUBFAMILY NOT NAMED; [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02605] origin recognition complex subunit 3; [PF07034] Origin recognition complex (ORC) subunit 3 N-terminus; [KOG2538] Origin recognition complex, subunit 3; [GO:0005664] nuclear origin of replication recognition complex; [PF02178] AT hook motif 55.86 0.8409 87 Mapoly0015s0126 [GO:0008641] small protein activating enzyme activity; [GO:0005524] ATP binding; [K10685] ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19]; [KOG2013] SMT3/SUMO-activating complex, catalytic component UBA2; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [PF14732] Ubiquitin/SUMO-activating enzyme ubiquitin-like domain 56.00 0.7930 88 Mapoly0081s0054 [PF13855] Leucine rich repeat; [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF13516] Leucine Rich repeat; [PF00069] Protein kinase domain; [PF08263] Leucine rich repeat N-terminal domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PF12799] Leucine Rich repeats (2 copies); [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 56.71 0.7246 89 Mapoly0013s0172 [K09228] KRAB domain-containing zinc finger protein; [PTHR11389:SF394] KRAB-RELATED C2H2-TYPE ZINC-FINGER PROTEIN; [PTHR11389] ZINC FINGER PROTEIN; [PF13894] C2H2-type zinc finger 57.71 0.6710 90 Mapoly0065s0078 [PTHR24115:SF171] SUBFAMILY NOT NAMED; [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [K10403] kinesin family member 22; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 57.72 0.8408 91 Mapoly0153s0002 [GO:0005524] ATP binding; [GO:0000166] nucleotide binding; [PF08264] Anticodon-binding domain of tRNA; [6.1.1.4] Leucine--tRNA ligase.; [PTHR11946] ISOLEUCYL, LEUCYL, TYROSYL, VALYL AND METHIONYL-TRNA SYNTHETASES; [K01869] leucyl-tRNA synthetase [EC:6.1.1.4]; [PF00133] tRNA synthetases class I (I, L, M and V); [KOG0437] Leucyl-tRNA synthetase; [GO:0006418] tRNA aminoacylation for protein translation; [GO:0004812] aminoacyl-tRNA ligase activity 57.83 0.7985 92 Mapoly0045s0076 - 58.92 0.6974 93 Mapoly0008s0081 [PTHR21286] NUCLEAR PORE COMPLEX PROTEIN NUP160; [K14303] nuclear pore complex protein Nup160; [KOG4521] Nuclear pore complex, Nup160 component; [PF11715] Nucleoporin Nup120/160 59.70 0.8045 94 Mapoly0021s0145 [PF02493] MORN repeat 60.45 0.7756 95 Mapoly0113s0005 - 61.19 0.7937 96 Mapoly0045s0061 [KOG1081] Transcription factor NSD1 and related SET domain proteins; [GO:0005515] protein binding; [PF00856] SET domain; [PTHR22884] SET DOMAIN PROTEINS 64.37 0.7881 97 Mapoly0032s0034 - 64.50 0.7911 98 Mapoly0154s0005 [PTHR22852] LETHAL(2)DENTICLELESS PROTEIN (RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN); [KOG0265] U5 snRNP-specific protein-like factor and related proteins; [K11790] denticleless; [GO:0005515] protein binding; [PF00400] WD domain, G-beta repeat 64.72 0.8336 99 Mapoly0009s0225 [PTHR22942] RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER; [KOG1564] DNA repair protein RHP57; [PTHR22942:SF24] SUBFAMILY NOT NAMED; [K10880] DNA-repair protein XRCC3; [PF08423] Rad51 65.48 0.7716 100 Mapoly0001s0105 [K02541] minichromosome maintenance protein 3; [KOG0479] DNA replication licensing factor, MCM3 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11630:SF46] DNA REPLICATION LICENSING FACTOR MCM3; [PF00493] MCM2/3/5 family; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 65.92 0.8382 101 Mapoly0001s0472 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED 66.09 0.8067 102 Mapoly0001s0481 [KOG1190] Polypyrimidine tract-binding protein; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [PTHR11546] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 66.11 0.7836 103 Mapoly0090s0047 [PF07719] Tetratricopeptide repeat; [PF13371] Tetratricopeptide repeat; [PF13414] TPR repeat; [KOG4162] Predicted calmodulin-binding protein; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR 66.33 0.7254 104 Mapoly0004s0096 [K11548] kinetochore protein Nuf2; [GO:0007067] mitosis; [PTHR21650] MEMBRALIN/KINETOCHORE PROTEIN NUF2; [PF03800] Nuf2 family; [KOG4438] Centromere-associated protein NUF2; [GO:0000775] chromosome, centromeric region; [PTHR21650:SF2] KINETOCHORE PROTEIN NUF2 66.54 0.8375 105 Mapoly0125s0003 - 69.20 0.8021 106 Mapoly0059s0004 - 69.80 0.7120 107 Mapoly0043s0050 [PTHR23019:SF0] SUBFAMILY NOT NAMED; [K14314] nuclear pore complex protein Nup210; [PF02368] Bacterial Ig-like domain (group 2); [PTHR23019] NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED; [KOG1833] Nuclear pore complex, gp210 component 70.21 0.7647 108 Mapoly0053s0008 - 70.94 0.8199 109 Mapoly0005s0051 [GO:0003723] RNA binding; [GO:0000339] RNA cap binding; [GO:0045292] mRNA cis splicing, via spliceosome; [GO:0051028] mRNA transport; [PF02854] MIF4G domain; [GO:0005515] protein binding; [KOG1104] Nuclear cap-binding complex, subunit NCBP1/CBP80; [K12882] nuclear cap-binding protein subunit 1; [GO:0016070] RNA metabolic process; [PTHR12412] CAP BINDING PROTEIN; [GO:0005846] nuclear cap binding complex; [PF09090] MIF4G like; [PF09088] MIF4G like 71.04 0.8000 110 Mapoly0069s0029 [PTHR10795:SF157] UNCHARACTERIZED; [KOG1114] Tripeptidyl peptidase II; [K01280] tripeptidyl-peptidase II [EC:3.4.14.10]; [GO:0004252] serine-type endopeptidase activity; [3.4.14.10] Tripeptidyl-peptidase II.; [PF00082] Subtilase family; [PF12580] Tripeptidyl peptidase II; [GO:0006508] proteolysis; [PTHR10795] PROPROTEIN CONVERTASE SUBTILISIN/KEXIN 72.17 0.7484 111 Mapoly0001s0406 [GO:0000922] spindle pole; [KOG2000] Gamma-tubulin complex, DGRIP91/SPC98 component; [PF04130] Spc97 / Spc98 family; [GO:0005856] cytoskeleton; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [GO:0007020] microtubule nucleation; [PTHR19302:SF14] GAMMA-TUBULIN COMPLEX COMPONENT 3 (GCP-3) 72.66 0.7500 112 Mapoly0064s0110 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR13394] ORIGIN RECOGNITION COMPLEX SUBUNIT 6; [PF05460] Origin recognition complex subunit 6 (ORC6); [GO:0005664] nuclear origin of replication recognition complex; [K02608] origin recognition complex subunit 6; [PTHR13394:SF0] SUBFAMILY NOT NAMED; [KOG4557] Origin recognition complex, subunit 6 73.00 0.8105 113 Mapoly0073s0027 [GO:0005524] ATP binding; [K07760] cyclin-dependent kinase [EC:2.7.11.22]; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [KOG0594] Protein kinase PCTAIRE and related kinases; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 74.46 0.8106 114 Mapoly0050s0134 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PF01751] Toprim domain; [PTHR10169] DNA TOPOISOMERASE/GYRASE; [GO:0006265] DNA topological change; [GO:0003918] DNA topoisomerase type II (ATP-hydrolyzing) activity; [PF00521] DNA gyrase/topoisomerase IV, subunit A; [KOG0355] DNA topoisomerase type II; [5.99.1.3] DNA topoisomerase (ATP-hydrolyzing).; [PF00204] DNA gyrase B; [K03164] DNA topoisomerase II [EC:5.99.1.3] 74.77 0.8263 115 Mapoly0013s0201 [PTHR23269:SF0] SUBFAMILY NOT NAMED; [KOG0128] RNA-binding protein SART3 (RRM superfamily); [PF05391] Lsm interaction motif; [GO:0003676] nucleic acid binding; [PTHR23269] RIBONUCLEOPROTEIN-RELATED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 75.58 0.7778 116 Mapoly0133s0013 [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10615] HISTONE ACETYLTRANSFERASE; [PF00856] SET domain 76.03 0.8010 117 Mapoly0006s0267 - 76.25 0.6749 118 Mapoly0114s0009 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [PF00514] Armadillo/beta-catenin-like repeat; [GO:0005515] protein binding; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [KOG0240] Kinesin (SMY1 subfamily); [GO:0008017] microtubule binding; [PTHR24115:SF221] SUBFAMILY NOT NAMED; [GO:0003777] microtubule motor activity 76.91 0.7480 119 Mapoly0103s0008 - 77.43 0.7893 120 Mapoly0013s0040 [GO:0005524] ATP binding; [KOG0359] Chaperonin complex component, TCP-1 zeta subunit (CCT6); [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family 77.59 0.7687 121 Mapoly0042s0088 [PF03801] HEC/Ndc80p family; [K11547] kinetochore protein NDC80; [PTHR10643] KINETOCHORE PROTEIN NDC80; [KOG0995] Centromere-associated protein HEC1 77.65 0.8204 122 Mapoly0044s0021 [KOG0275] Conserved WD40 repeat-containing protein; [PTHR22848] WD40 REPEAT PROTEIN; [GO:0005515] protein binding; [K13111] WD40 repeat-containing protein SMU1; [PF00400] WD domain, G-beta repeat 77.77 0.7647 123 Mapoly0010s0191 [PF04055] Radical SAM superfamily; [PTHR13930] RSAFD1-RELATED; [PF00258] Flavodoxin; [PF08608] Wyosine base formation; [GO:0016491] oxidoreductase activity; [PTHR13930:SF0] SUBFAMILY NOT NAMED; [GO:0003824] catalytic activity; [GO:0051536] iron-sulfur cluster binding; [KOG1160] Fe-S oxidoreductase; [GO:0010181] FMN binding 79.20 0.7744 124 Mapoly0067s0089 [GO:0005515] protein binding; [PF00498] FHA domain; [PTHR23308] NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 80.31 0.8086 125 Mapoly0138s0046 [KOG1803] DNA helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PF13086] AAA domain; [PF13087] AAA domain 80.62 0.7740 126 Mapoly0122s0062 [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 80.99 0.8044 127 Mapoly0119s0016 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [KOG0480] DNA replication licensing factor, MCM6 component; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630:SF43] DNA REPLICATION LICENSING FACTOR MCM6; [K02542] minichromosome maintenance protein 6; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain 81.98 0.8118 128 Mapoly0074s0003 [GO:0003677] DNA binding; [PF12254] DNA polymerase alpha subunit p180 N terminal; [GO:0006260] DNA replication; [GO:0001882] nucleoside binding; [K02320] DNA polymerase alpha subunit A [EC:2.7.7.7]; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0006270] DNA replication initiation; [PF08996] DNA Polymerase alpha zinc finger; [KOG0970] DNA polymerase alpha, catalytic subunit; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT 82.46 0.7697 129 Mapoly0043s0064 [PF10979] Protein of unknown function (DUF2786) 83.71 0.7969 130 Mapoly0078s0017 - 83.89 0.8192 131 Mapoly0002s0133 [GO:0007076] mitotic chromosome condensation; [PTHR13108] FAMILY NOT NAMED; [PF05786] Condensin complex subunit 2; [KOG2328] Chromosome condensation complex Condensin, subunit H; [GO:0000796] condensin complex; [K06676] condensin complex subunit 2 83.98 0.8004 132 Mapoly0068s0001 [K10736] minichromosome maintenance protein 10; [GO:0006260] DNA replication; [PTHR13454] FAMILY NOT NAMED; [PF09329] Primase zinc finger; [GO:0005634] nucleus 85.85 0.7892 133 Mapoly0027s0041 [GO:0005643] nuclear pore; [PTHR13437] NUCLEOPORIN P58/P45 (NUCLEOPORIN-LIKE PROTEIN 1); [GO:0006913] nucleocytoplasmic transport 86.16 0.7821 134 Mapoly0009s0039 [GO:0030915] Smc5-Smc6 complex; [KOG2866] Uncharacterized conserved protein; [PTHR16140:SF0] SUBFAMILY NOT NAMED; [PTHR16140] UNCHARACTERIZED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08743] Nse4 C-terminal 86.87 0.8075 135 Mapoly0099s0028 [GO:0005524] ATP binding; [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family; [KOG0360] Chaperonin complex component, TCP-1 alpha subunit (CCT1) 87.46 0.7480 136 Mapoly0052s0095 [GO:0005643] nuclear pore; [PTHR31344:SF0] SUBFAMILY NOT NAMED; [K14310] nuclear pore complex protein Nup205; [PF11894] Protein of unknown function (DUF3414); [PTHR31344] FAMILY NOT NAMED; [KOG1835] Uncharacterized conserved protein 88.60 0.7568 137 Mapoly0144s0003 - 88.74 0.7757 138 Mapoly0025s0108 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity; [PF11995] Domain of unknown function (DUF3490) 88.75 0.7366 139 Mapoly0063s0076 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF0] CELL DIVISION PROTEIN KINASE 7; [K02202] cyclin-dependent kinase 7 [EC:2.7.11.22]; [KOG0659] Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 90.25 0.7361 140 Mapoly0042s0035 [PF01433] Peptidase family M1; [GO:0008237] metallopeptidase activity; [3.4.11.2] Membrane alanyl aminopeptidase.; [GO:0008270] zinc ion binding; [PTHR11533] PROTEASE M1 ZINC METALLOPROTEASE; [KOG1046] Puromycin-sensitive aminopeptidase and related aminopeptidases; [K01256] aminopeptidase N [EC:3.4.11.2]; [GO:0006508] proteolysis; [PF11940] Domain of unknown function (DUF3458) 90.50 0.6956 141 Mapoly0022s0008 [PTHR22808] NCL1(YEAST)-RELATED NOL1/NOP2/FMU(SUN) DOMAIN-CONTAINING; [PF01189] NOL1/NOP2/sun family; [KOG2198] tRNA cytosine-5-methylases and related enzymes of the NOL1/NOP2/sun superfamily; [PTHR22808:SF1] PUTATIVE METHYLTRANSFERASE NCL1(YEAST)-RELATED 91.49 0.7708 142 Mapoly0028s0139 [PTHR11200] INOSITOL 5-PHOSPHATASE; [PF03372] Endonuclease/Exonuclease/phosphatase family; [KOG0565] Inositol polyphosphate 5-phosphatase and related proteins 92.52 0.6323 143 Mapoly0033s0098 [PTHR16047] RFWD3 PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PTHR16047:SF7] RFWD3 PROTEIN-RELATED; [KOG1645] RING-finger-containing E3 ubiquitin ligase 92.63 0.7651 144 Mapoly0084s0004 [KOG0446] Vacuolar sorting protein VPS1, dynamin, and related proteins; [PF00350] Dynamin family; [PTHR11566] DYNAMIN; [GO:0003924] GTPase activity; [GO:0005525] GTP binding 92.79 0.7766 145 Mapoly0051s0060 [PTHR31399:SF0] SUBFAMILY NOT NAMED; [PF03121] Herpesviridae UL52/UL70 DNA primase; [GO:0006260] DNA replication; [GO:0003896] DNA primase activity; [PTHR31399] FAMILY NOT NAMED 95.25 0.7515 146 Mapoly0221s0003 - 95.90 0.7770 147 Mapoly0063s0085 [KOG3655] Drebrins and related actin binding proteins; [PF04548] AIG1 family; [PTHR10903] GTPASE, IMAP FAMILY MEMBER-RELATED; [PF11886] Domain of unknown function (DUF3406); [GO:0005525] GTP binding 96.75 0.7010 148 Mapoly0008s0208 [GO:0003755] peptidyl-prolyl cis-trans isomerase activity; [PTHR11071] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF00160] Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; [GO:0005515] protein binding; [GO:0000413] protein peptidyl-prolyl isomerization; [GO:0006457] protein folding; [K12736] peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8]; [5.2.1.8] Peptidylprolyl isomerase.; [KOG0882] Cyclophilin-related peptidyl-prolyl cis-trans isomerase; [PF00400] WD domain, G-beta repeat 96.98 0.7460 149 Mapoly0051s0023 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III 97.40 0.7960 150 Mapoly0083s0034 - 97.57 0.7485 151 Mapoly0116s0041 [PF13297] Telomere stability C-terminal; [PTHR12786:SF2] SPLICING FACTOR 3A; [PF12108] Splicing factor SF3a60 binding domain; [KOG2636] Splicing factor 3a, subunit 3; [PTHR12786] SPLICING FACTOR SF3A-RELATED; [K12827] splicing factor 3A subunit 3; [PF11931] Domain of unknown function (DUF3449) 97.70 0.7744 152 Mapoly0087s0011 [GO:0005634] nucleus; [PF07557] Shugoshin C terminus; [GO:0000775] chromosome, centromeric region; [GO:0045132] meiotic chromosome segregation 98.95 0.7589 153 Mapoly0021s0007 [PTHR11851:SF85] AGR251CP; [3.4.24.56] Insulysin.; [KOG0959] N-arginine dibasic convertase NRD1 and related Zn2+-dependent endopeptidases, insulinase superfamily; [K01408] insulysin [EC:3.4.24.56]; [PTHR11851] METALLOPROTEASE; [PF05193] Peptidase M16 inactive domain; [PF00675] Insulinase (Peptidase family M16) 99.02 0.7015 154 Mapoly0190s0010 [GO:0008762] UDP-N-acetylmuramate dehydrogenase activity; [PTHR10801:SF0] 24-DEHYDROCHOLESTEROL REDUCTASE; [GO:0050660] flavin adenine dinucleotide binding; [KOG1262] FAD-binding protein DIMINUTO; [K09828] delta24-sterol reductase [EC:1.3.1.72]; [GO:0055114] oxidation-reduction process; [1.3.1.72] Delta(24)-sterol reductase.; [GO:0016491] oxidoreductase activity; [PTHR10801] 24-DEHYDROCHOLESTEROL REDUCTASE; [PF01565] FAD binding domain 99.02 0.7149 155 Mapoly0091s0001 [PTHR14190:SF7] SUBFAMILY NOT NAMED; [PF04129] Vps52 / Sac2 family; [KOG1961] Vacuolar sorting protein VPS52/suppressor of actin Sac2; [PTHR14190] SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52 99.12 0.6826 156 Mapoly0076s0033 [PF10444] Nbl1 / Borealin N terminal 99.87 0.7937 157 Mapoly0005s0161 [GO:0003677] DNA binding; [PTHR13451:SF0] SUBFAMILY NOT NAMED; [3.1.22.-] Endodeoxyribonucleases producing other than 5'-phosphomonoesters.; [K08991] crossover junction endonuclease MUS81 [EC:3.1.22.-]; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PF02732] ERCC4 domain 100.22 0.7212 158 Mapoly0027s0013 [KOG4487] Uncharacterized conserved protein; [PF09696] Ctf8; [K11270] chromosome transmission fidelity protein 8 101.44 0.7905 159 Mapoly0001s0257 - 101.78 0.6929 160 Mapoly0109s0019 [KOG1375] Beta tubulin; [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [K07375] tubulin beta; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [GO:0005525] GTP binding 102.70 0.7254 161 Mapoly0004s0202 - 103.37 0.7697 162 Mapoly0034s0031 [GO:0007094] mitotic spindle assembly checkpoint; [K06638] mitotic spindle assembly checkpoint protein MAD1; [KOG4593] Mitotic checkpoint protein MAD1; [PTHR23168] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 (MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1); [PF05557] Mitotic checkpoint protein; [PTHR23168:SF0] SUBFAMILY NOT NAMED 103.92 0.7776 163 Mapoly0008s0107 [K12852] 116 kDa U5 small nuclear ribonucleoprotein component; [PF00009] Elongation factor Tu GTP binding domain; [PF00679] Elongation factor G C-terminus; [GO:0003924] GTPase activity; [PTHR23115] TRANSLATION FACTOR; [PTHR23115:SF5] 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT; [PF03764] Elongation factor G, domain IV; [KOG0468] U5 snRNP-specific protein; [GO:0005525] GTP binding; [PF03144] Elongation factor Tu domain 2 105.05 0.7759 164 Mapoly0007s0014 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02540] minichromosome maintenance protein 2; [PF12619] Mini-chromosome maintenance protein 2; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PTHR11630:SF44] DNA REPLICATION LICENSING FACTOR MCM2; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [KOG0477] DNA replication licensing factor, MCM2 component 106.40 0.7918 165 Mapoly0112s0022 [PTHR19932] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; [GO:0005515] protein binding; [KOG1274] WD40 repeat protein; [K11274] chromosome transmission fidelity protein 4; [PTHR19932:SF10] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN 1; [PF00400] WD domain, G-beta repeat; [PF12341] Protein of unknown function (DUF3639) 106.70 0.7929 166 Mapoly0004s0127 - 106.95 0.7721 167 Mapoly0179s0001 [PTHR10994] RETICULON; [PF02453] Reticulon; [KOG1792] Reticulon 107.30 0.7921 168 Mapoly0011s0194 [PF02897] Prolyl oligopeptidase, N-terminal beta-propeller domain; [GO:0008236] serine-type peptidase activity; [PTHR11757:SF3] OLIGOPEPTIDASE B (LYSYL AND ARGININYL OLIGOPEPTIDASE); [3.4.21.83] Oligopeptidase B.; [GO:0070008] serine-type exopeptidase activity; [K01354] oligopeptidase B [EC:3.4.21.83]; [GO:0004252] serine-type endopeptidase activity; [GO:0006508] proteolysis; [PTHR11757] PROTEASE FAMILY S9A OLIGOPEPTIDASE; [PF00326] Prolyl oligopeptidase family; [KOG2237] Predicted serine protease 107.34 0.6929 169 Mapoly0055s0064 - 107.50 0.7896 170 Mapoly0013s0136 [PF13855] Leucine rich repeat; [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF00069] Protein kinase domain; [PF08263] Leucine rich repeat N-terminal domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PF12799] Leucine Rich repeats (2 copies); [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 108.66 0.6543 171 Mapoly0003s0057 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination 108.83 0.7913 172 Mapoly0081s0071 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [PF00628] PHD-finger; [GO:0005515] protein binding; [PF12738] twin BRCT domain; [GO:0046872] metal ion binding 109.44 0.7875 173 Mapoly0029s0120 [PF05178] KRI1-like family; [KOG2409] KRR1-interacting protein involved in 40S ribosome biogenesis; [PTHR14490] ZINC FINGER, ZZ TYPE; [PF12936] KRI1-like family C-terminal 111.49 0.7154 174 Mapoly0103s0054 [PTHR24067:SF59] UBIQUITIN-CONJUGATING ENZYME E2 T; [K13960] ubiquitin-conjugating enzyme E2 T [EC:6.3.2.19]; [PTHR24067] UBIQUITIN-CONJUGATING ENZYME E2; [GO:0016881] acid-amino acid ligase activity; [6.3.2.19] Ubiquitin--protein ligase.; [KOG0417] Ubiquitin-protein ligase; [PF00179] Ubiquitin-conjugating enzyme 111.73 0.7173 175 Mapoly0177s0008 [GO:0006260] DNA replication; [PF13191] AAA ATPase domain; [GO:0005634] nucleus; [KOG2543] Origin recognition complex, subunit 5; [PF14630] Origin recognition complex (ORC) subunit 5 C-terminus; [PTHR12705] ORIGIN RECOGNITION COMPLEX SUBUNIT 5; [GO:0000808] origin recognition complex; [K02607] origin recognition complex subunit 5 112.64 0.7768 176 Mapoly0005s0138 - 113.15 0.7458 177 Mapoly0083s0072 [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [PF00570] HRDC domain 113.49 0.7544 178 Mapoly0035s0099 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02321] DNA polymerase alpha subunit B; [PTHR23061:SF12] SUBFAMILY NOT NAMED; [KOG1625] DNA polymerase alpha-primase complex, polymerase-associated subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [PTHR23061] DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; [GO:0003887] DNA-directed DNA polymerase activity; [PF08418] DNA polymerase alpha subunit B N-terminal 114.79 0.7895 179 Mapoly0030s0009 [PF00505] HMG (high mobility group) box; [KOG0526] Nucleosome-binding factor SPN, POB3 subunit; [PF03531] Structure-specific recognition protein (SSRP1); [PTHR13711:SF39] SUBFAMILY NOT NAMED; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [PF08512] Histone chaperone Rttp106-like; [K09272] structure-specific recognition protein 1 115.89 0.7546 180 Mapoly0019s0059 [PTHR31398:SF0] SUBFAMILY NOT NAMED; [PTHR31398] FAMILY NOT NAMED; [PF03962] Mnd1 family; [KOG3433] Protein involved in meiotic recombination/predicted coiled-coil protein 116.29 0.7692 181 Mapoly0065s0034 [GO:0000287] magnesium ion binding; [GO:0004743] pyruvate kinase activity; [GO:0006096] glycolysis; [GO:0030955] potassium ion binding; [PF02887] Pyruvate kinase, alpha/beta domain; [PF00224] Pyruvate kinase, barrel domain; [KOG2323] Pyruvate kinase; [PTHR11817] PYRUVATE KINASE 116.29 0.7524 182 Mapoly0005s0010 - 116.57 0.7746 183 Mapoly0051s0088 [GO:0005524] ATP binding; [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family; [KOG0357] Chaperonin complex component, TCP-1 epsilon subunit (CCT5) 117.48 0.7212 184 Mapoly0039s0099 [PF00169] PH domain; [PTHR12092] PLECKSTRIN 118.97 0.6689 185 Mapoly0048s0068 [KOG0653] Cyclin B and related kinase-activating proteins; [PF00134] Cyclin, N-terminal domain; [PTHR10177] CYCLINE; [PF02984] Cyclin, C-terminal domain; [GO:0005634] nucleus; [K05868] cyclin B 120.40 0.7609 186 Mapoly0117s0005 [K13109] IK cytokine; [PTHR12765] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [KOG2498] IK cytokine down-regulator of HLA class II; [PF07807] RED-like protein C-terminal region; [PTHR12765:SF5] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [GO:0005634] nucleus; [PF07808] RED-like protein N-terminal region 121.00 0.7357 187 Mapoly0051s0073 [PF14675] FANCI solenoid 1; [PTHR21818:SF0] SUBFAMILY NOT NAMED; [PF14680] FANCI helical domain 2; [KOG4553] Uncharacterized conserved protein; [K10895] fanconi anemia group I protein; [PF14679] FANCI helical domain 1; [GO:0006281] DNA repair; [PF14678] FANCI solenoid 4; [PTHR21818] BC025462 PROTEIN; [PF14676] FANCI solenoid 2 121.98 0.7584 188 Mapoly0189s0011 [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain 122.67 0.7622 189 Mapoly0039s0112 [PF03330] Rare lipoprotein A (RlpA)-like double-psi beta-barrel 122.74 0.7332 190 Mapoly0019s0115 [PTHR23002] ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN; [PF14392] Zinc knuckle; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding 123.87 0.7134 191 Mapoly0060s0041 [PF05303] Protein of unknown function (DUF727); [PF12807] Translation initiation factor eIF3 subunit 135; [PF13236] Clustered mitochondria; [PF13424] Tetratricopeptide repeat; [PTHR12601] EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT (EIF-3); [PF15044] Mitochondrial function, CLU-N-term 125.84 0.7183 192 Mapoly0003s0259 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PTHR24420:SF474] SUBFAMILY NOT NAMED; [PF00069] Protein kinase domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 127.01 0.7623 193 Mapoly0098s0009 [K01104] protein-tyrosine phosphatase [EC:3.1.3.48]; [PF00581] Rhodanese-like domain; [PTHR10828:SF17] M-PHASE INDUCER PHOSPHATASE (DUAL SPECIFICITY PHOSPHATASE CDC25); [PTHR10828] M-PHASE INDUCER PHOSPHATASE (DUAL SPECIFICITY PHOSPHATASE CDC25); [3.1.3.48] Protein-tyrosine-phosphatase. 127.94 0.7726 194 Mapoly0025s0128 [PF00134] Cyclin, N-terminal domain; [PTHR10177] CYCLINE; [PF02984] Cyclin, C-terminal domain; [GO:0005634] nucleus; [PTHR10177:SF49] CYCLIN-A; [KOG0654] G2/Mitotic-specific cyclin A; [K06627] cyclin A 128.48 0.7732 195 Mapoly0092s0013 [GO:0003723] RNA binding; [PTHR13326] TRNA PSEUDOURIDINE SYNTHASE D; [GO:0001522] pseudouridine synthesis; [GO:0009451] RNA modification; [PF01142] tRNA pseudouridine synthase D (TruD); [GO:0009982] pseudouridine synthase activity; [KOG2339] Uncharacterized conserved protein 128.72 0.7177 196 Mapoly0067s0015 [PTHR13271] UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE; [GO:0005515] protein binding; [PF00856] SET domain; [PF09273] Rubisco LSMT substrate-binding 130.23 0.6757 197 Mapoly0037s0093 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG4280] Kinesin-like protein; [PTHR24115:SF87] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [PF12711] Kinesin motor; [GO:0003777] microtubule motor activity 130.66 0.7404 198 Mapoly0019s0032 - 132.02 0.7499 199 Mapoly0002s0297 [PTHR11731] PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; [KOG2100] Dipeptidyl aminopeptidase; [GO:0008236] serine-type peptidase activity; [PF07676] WD40-like Beta Propeller Repeat; [GO:0006508] proteolysis; [PF00326] Prolyl oligopeptidase family 132.48 0.7155 200 Mapoly0149s0034 [PTHR32227] FAMILY NOT NAMED; [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [GO:0005975] carbohydrate metabolic process; [PF00332] Glycosyl hydrolases family 17 132.63 0.6587