| 1 |
Mapoly0005s0174
| [GO:0005524] ATP binding; [KOG0933] Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E); [GO:0007076] mitotic chromosome condensation; [GO:0005515] protein binding; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0000796] condensin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PTHR18937:SF9] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC2; [K06674] structural maintenance of chromosome 2; [PF06470] SMC proteins Flexible Hinge Domain | 3.00 | 0.9326 |
| 2 |
Mapoly0060s0012
| [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [K11498] centromeric protein E; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity | 3.87 | 0.9257 |
| 3 |
Mapoly0034s0119
| [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity | 4.00 | 0.9293 |
| 4 |
Mapoly0001s0188
| - | 6.63 | 0.9242 |
| 5 |
Mapoly0042s0023
| [GO:0005524] ATP binding; [2.7.12.1] Dual-specificity kinase.; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [K08866] serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]; [PTHR22974] MIXED LINEAGE PROTEIN KINASE | 6.71 | 0.9099 |
| 6 |
Mapoly0032s0119
| [GO:0007076] mitotic chromosome condensation; [K06678] condensin complex subunit 3; [GO:0000796] condensin complex; [PTHR14418] CONDENSIN COMPLEX SUBUNIT 3-RELATED; [PF12719] Nuclear condensing complex subunits, C-term domain | 8.83 | 0.9184 |
| 7 |
Mapoly0020s0135
| [PF03941] Inner centromere protein, ARK binding region; [PTHR13142:SF1] INCENP; [KOG1295] Nonsense-mediated decay protein Upf3; [PTHR13142] INNER CENTROMERE PROTEIN | 8.94 | 0.9216 |
| 8 |
Mapoly0043s0047
| [GO:0005515] protein binding; [PF00612] IQ calmodulin-binding motif; [PTHR25069] FAMILY NOT NAMED; [PF00307] Calponin homology (CH) domain | 10.91 | 0.9153 |
| 9 |
Mapoly0022s0167
| [PF12717] non-SMC mitotic condensation complex subunit 1; [PF12922] non-SMC mitotic condensation complex subunit 1, N-term; [GO:0007076] mitotic chromosome condensation; [PTHR14222] CONDENSIN; [KOG0414] Chromosome condensation complex Condensin, subunit D2; [K06677] condensin complex subunit 1 | 10.95 | 0.9115 |
| 10 |
Mapoly0033s0057
| [2.3.1.-] Transferring groups other than amino-acyl groups.; [PTHR11076:SF1] ESTABLISHMENT OF COHESION 1 (ECO1) HOMOLOG; [PF13880] ESCO1/2 acetyl-transferase; [PF13878] zinc-finger of acetyl-transferase ESCO; [KOG3014] Protein involved in establishing cohesion between sister chromatids during DNA replication; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [K11268] N-acetyltransferase [EC:2.3.1.-] | 11.66 | 0.8870 |
| 11 |
Mapoly0011s0202
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain | 12.00 | 0.9020 |
| 12 |
Mapoly0113s0048
| [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [KOG1408] WD40 repeat protein; [PF00400] WD domain, G-beta repeat | 12.85 | 0.9037 |
| 13 |
Mapoly0001s0472
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED | 13.23 | 0.8709 |
| 14 |
Mapoly0102s0001
| [K06228] fused [EC:2.7.11.1]; [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR22983:SF6] MAPK KINASE 2-RELATED; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [KOG0598] Ribosomal protein S6 kinase and related proteins; [PF13646] HEAT repeats | 13.49 | 0.8998 |
| 15 |
Mapoly0072s0051
| [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [KOG0597] Serine-threonine protein kinase FUSED; [GO:0006468] protein phosphorylation | 13.86 | 0.8909 |
| 16 |
Mapoly0052s0095
| [GO:0005643] nuclear pore; [PTHR31344:SF0] SUBFAMILY NOT NAMED; [K14310] nuclear pore complex protein Nup205; [PF11894] Protein of unknown function (DUF3414); [PTHR31344] FAMILY NOT NAMED; [KOG1835] Uncharacterized conserved protein | 14.70 | 0.8366 |
| 17 |
Mapoly0209s0008
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF67] DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE | 15.00 | 0.8964 |
| 18 |
Mapoly0001s0076
| [PF00225] Kinesin motor domain; [GO:0007018] microtubule-based movement; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0008017] microtubule binding; [KOG4280] Kinesin-like protein; [PF06548] Kinesin-related; [GO:0003777] microtubule motor activity; [GO:0005871] kinesin complex | 15.81 | 0.9055 |
| 19 |
Mapoly0094s0016
| [KOG4674] Uncharacterized conserved coiled-coil protein | 16.12 | 0.9007 |
| 20 |
Mapoly0006s0290
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR10670:SF0] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A; [GO:0000166] nucleotide binding; [GO:0008270] zinc ion binding; [2.7.7.7] DNA-directed DNA polymerase.; [KOG1798] DNA polymerase epsilon, catalytic subunit A; [PF08490] Domain of unknown function (DUF1744); [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF00136] DNA polymerase family B; [GO:0008622] epsilon DNA polymerase complex; [K02324] DNA polymerase epsilon subunit 1 [EC:2.7.7.7]; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10670] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A | 18.38 | 0.8698 |
| 21 |
Mapoly0003s0057
| [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination | 19.77 | 0.8744 |
| 22 |
Mapoly0009s0056
| [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PF08311] Mad3/BUB1 homology region 1; [K02178] checkpoint serine/threonine-protein kinase [EC:2.7.11.1]; [KOG1166] Mitotic checkpoint serine/threonine protein kinase; [PTHR14030] MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 | 20.78 | 0.8720 |
| 23 |
Mapoly0081s0071
| [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [PF00628] PHD-finger; [GO:0005515] protein binding; [PF12738] twin BRCT domain; [GO:0046872] metal ion binding | 23.24 | 0.8639 |
| 24 |
Mapoly0016s0083
| [PF12214] Cell cycle regulated microtubule associated protein; [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [PTHR14326:SF9] TARGETING PROTEIN FOR XKLP2; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2) | 25.26 | 0.8752 |
| 25 |
Mapoly0085s0026
| [PF00533] BRCA1 C Terminus (BRCT) domain; [PTHR23196] PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN | 25.69 | 0.8801 |
| 26 |
Mapoly0007s0003
| [GO:0005515] protein binding; [PTHR19918:SF8] gb def: Meiosis-specific APC/C activator protein AMA1 (Activator of meiotic APC/C protei; [KOG0305] Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits; [K03363] cell division cycle 20, cofactor of APC complex; [PTHR19918] CELL DIVISION CYCLE 20 (CDC20) (FIZZY)-RELATED; [PF00400] WD domain, G-beta repeat | 27.69 | 0.8279 |
| 27 |
Mapoly0003s0063
| [GO:0005524] ATP binding; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24361:SF129] MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE; [GO:0006468] protein phosphorylation; [PTHR24361] MITOGEN-ACTIVATED KINASE KINASE KINASE | 27.82 | 0.8859 |
| 28 |
Mapoly0098s0032
| [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [PF11721] Di-glucose binding within endoplasmic reticulum; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity | 27.87 | 0.8759 |
| 29 |
Mapoly0045s0061
| [KOG1081] Transcription factor NSD1 and related SET domain proteins; [GO:0005515] protein binding; [PF00856] SET domain; [PTHR22884] SET DOMAIN PROTEINS | 27.93 | 0.8230 |
| 30 |
Mapoly0023s0118
| [PTHR12446] TESMIN/TSO1-RELATED; [PF03638] Tesmin/TSO1-like CXC domain, cysteine-rich domain | 28.00 | 0.8666 |
| 31 |
Mapoly0097s0064
| [PTHR13710:SF1] ROTHMUND-THOMSON SYNDROME DNA HELICASE RECQ4; [GO:0005524] ATP binding; [PF11719] DNA replication and checkpoint protein; [K10730] ATP-dependent DNA helicase Q4 [EC:3.6.4.12]; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [GO:0003676] nucleic acid binding; [PF02037] SAP domain | 28.28 | 0.8604 |
| 32 |
Mapoly0050s0134
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PF01751] Toprim domain; [PTHR10169] DNA TOPOISOMERASE/GYRASE; [GO:0006265] DNA topological change; [GO:0003918] DNA topoisomerase type II (ATP-hydrolyzing) activity; [PF00521] DNA gyrase/topoisomerase IV, subunit A; [KOG0355] DNA topoisomerase type II; [5.99.1.3] DNA topoisomerase (ATP-hydrolyzing).; [PF00204] DNA gyrase B; [K03164] DNA topoisomerase II [EC:5.99.1.3] | 29.24 | 0.8844 |
| 33 |
Mapoly0038s0027
| [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PTHR10629:SF11] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF12047] Cytosine specific DNA methyltransferase replication foci domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. | 30.40 | 0.8104 |
| 34 |
Mapoly0003s0120
| [GO:0003677] DNA binding; [PTHR12708:SF0] SUBFAMILY NOT NAMED; [GO:0006260] DNA replication; [PF12213] DNA polymerases epsilon N terminal; [2.7.7.7] DNA-directed DNA polymerase.; [PTHR12708] DNA POLYMERASE EPSILON SUBUNIT B; [KOG3818] DNA polymerase epsilon, subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [GO:0003887] DNA-directed DNA polymerase activity; [K02325] DNA polymerase epsilon subunit 2 [EC:2.7.7.7] | 30.50 | 0.8256 |
| 35 |
Mapoly0033s0145
| - | 30.94 | 0.8603 |
| 36 |
Mapoly0061s0044
| [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2) | 31.18 | 0.8671 |
| 37 |
Mapoly0167s0015
| [KOG1076] Translation initiation factor 3, subunit c (eIF-3c); [K03252] translation initiation factor eIF-3 subunit 8; [PF05470] Eukaryotic translation initiation factor 3 subunit 8 N-terminus; [PTHR13937:SF0] SUBFAMILY NOT NAMED; [GO:0003743] translation initiation factor activity; [GO:0005515] protein binding; [PTHR13937] EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 (EIF3S8)-RELATED; [GO:0031369] translation initiation factor binding; [PF01399] PCI domain; [GO:0006413] translational initiation; [GO:0005852] eukaryotic translation initiation factor 3 complex | 31.75 | 0.7721 |
| 38 |
Mapoly0047s0105
| [KOG4308] LRR-containing protein; [PTHR10098] RAPSYN-RELATED; [PF13516] Leucine Rich repeat; [PF13414] TPR repeat | 32.03 | 0.8511 |
| 39 |
Mapoly0006s0242
| - | 34.48 | 0.8644 |
| 40 |
Mapoly0001s0044
| [PTHR31110] FAMILY NOT NAMED | 34.64 | 0.8273 |
| 41 |
Mapoly0057s0017
| - | 35.50 | 0.8573 |
| 42 |
Mapoly0189s0011
| [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain | 35.71 | 0.8400 |
| 43 |
Mapoly0002s0133
| [GO:0007076] mitotic chromosome condensation; [PTHR13108] FAMILY NOT NAMED; [PF05786] Condensin complex subunit 2; [KOG2328] Chromosome condensation complex Condensin, subunit H; [GO:0000796] condensin complex; [K06676] condensin complex subunit 2 | 35.72 | 0.8447 |
| 44 |
Mapoly0013s0201
| [PTHR23269:SF0] SUBFAMILY NOT NAMED; [KOG0128] RNA-binding protein SART3 (RRM superfamily); [PF05391] Lsm interaction motif; [GO:0003676] nucleic acid binding; [PTHR23269] RIBONUCLEOPROTEIN-RELATED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 37.71 | 0.8096 |
| 45 |
Mapoly0059s0004
| - | 38.16 | 0.7240 |
| 46 |
Mapoly0070s0053
| [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF09382] RQC domain; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [K10901] bloom syndrome protein [EC:3.6.4.12]; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain | 38.96 | 0.8230 |
| 47 |
Mapoly0004s0096
| [K11548] kinetochore protein Nuf2; [GO:0007067] mitosis; [PTHR21650] MEMBRALIN/KINETOCHORE PROTEIN NUF2; [PF03800] Nuf2 family; [KOG4438] Centromere-associated protein NUF2; [GO:0000775] chromosome, centromeric region; [PTHR21650:SF2] KINETOCHORE PROTEIN NUF2 | 39.76 | 0.8609 |
| 48 |
Mapoly0043s0050
| [PTHR23019:SF0] SUBFAMILY NOT NAMED; [K14314] nuclear pore complex protein Nup210; [PF02368] Bacterial Ig-like domain (group 2); [PTHR23019] NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED; [KOG1833] Nuclear pore complex, gp210 component | 39.80 | 0.8011 |
| 49 |
Mapoly0025s0127
| - | 39.95 | 0.8475 |
| 50 |
Mapoly0010s0152
| [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PTHR13561:SF5] DNA REPLICATION REGULATOR DPB11; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain | 40.42 | 0.8474 |
