Guide Gene
- Gene ID
- Mapoly0052s0095
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [GO:0005643] nuclear pore; [PTHR31344:SF0] SUBFAMILY NOT NAMED; [K14310] nuclear pore complex protein Nup205; [PF11894] Protein of unknown function (DUF3414); [PTHR31344] FAMILY NOT NAMED; [KOG1835] Uncharacterized conserved protein
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0052s0095 [GO:0005643] nuclear pore; [PTHR31344:SF0] SUBFAMILY NOT NAMED; [K14310] nuclear pore complex protein Nup205; [PF11894] Protein of unknown function (DUF3414); [PTHR31344] FAMILY NOT NAMED; [KOG1835] Uncharacterized conserved protein 0.00 1.0000 1 Mapoly0043s0050 [PTHR23019:SF0] SUBFAMILY NOT NAMED; [K14314] nuclear pore complex protein Nup210; [PF02368] Bacterial Ig-like domain (group 2); [PTHR23019] NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED; [KOG1833] Nuclear pore complex, gp210 component 1.00 0.8894 2 Mapoly0092s0013 [GO:0003723] RNA binding; [PTHR13326] TRNA PSEUDOURIDINE SYNTHASE D; [GO:0001522] pseudouridine synthesis; [GO:0009451] RNA modification; [PF01142] tRNA pseudouridine synthase D (TruD); [GO:0009982] pseudouridine synthase activity; [KOG2339] Uncharacterized conserved protein 1.73 0.8378 3 Mapoly0167s0015 [KOG1076] Translation initiation factor 3, subunit c (eIF-3c); [K03252] translation initiation factor eIF-3 subunit 8; [PF05470] Eukaryotic translation initiation factor 3 subunit 8 N-terminus; [PTHR13937:SF0] SUBFAMILY NOT NAMED; [GO:0003743] translation initiation factor activity; [GO:0005515] protein binding; [PTHR13937] EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 (EIF3S8)-RELATED; [GO:0031369] translation initiation factor binding; [PF01399] PCI domain; [GO:0006413] translational initiation; [GO:0005852] eukaryotic translation initiation factor 3 complex 2.65 0.8220 4 Mapoly0001s0472 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED 6.32 0.8389 5 Mapoly0108s0041 [PTHR14978:SF0] SUBFAMILY NOT NAMED; [PTHR14978] BETA-CATENIN-LIKE PROTEIN 1 (NUCLEAR ASSOCIATED PROTEIN); [K12864] beta-catenin-like protein 1; [KOG2734] Uncharacterized conserved protein; [PF08216] Catenin-beta-like, Arm-motif containing nuclear 8.37 0.8089 6 Mapoly0023s0072 [3.1.27.-] Endoribonucleases producing other than 5'-phosphomonoesters.; [K13148] integrator complex subunit 11 [EC:3.1.27.-]; [PF07521] RNA-metabolising metallo-beta-lactamase; [PTHR11203] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF00753] Metallo-beta-lactamase superfamily; [PTHR11203:SF11] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF10996] Beta-Casp domain; [KOG1136] Predicted cleavage and polyadenylation specificity factor (CPSF subunit) 8.66 0.7949 7 Mapoly0008s0081 [PTHR21286] NUCLEAR PORE COMPLEX PROTEIN NUP160; [K14303] nuclear pore complex protein Nup160; [KOG4521] Nuclear pore complex, Nup160 component; [PF11715] Nucleoporin Nup120/160 10.00 0.8289 8 Mapoly0101s0062 [GO:0003677] DNA binding; [PTHR20856:SF7] DNA-DIRECTED RNA POLYMERASE II SUBUNIT 2; [KOG0214] RNA polymerase II, second largest subunit; [PF04567] RNA polymerase Rpb2, domain 5; [K03010] DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]; [PF04565] RNA polymerase Rpb2, domain 3; [PTHR20856] DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2; [PF00562] RNA polymerase Rpb2, domain 6; [PF04566] RNA polymerase Rpb2, domain 4; [GO:0032549] ribonucleoside binding; [PF04561] RNA polymerase Rpb2, domain 2; [GO:0006351] transcription, DNA-dependent; [GO:0003899] DNA-directed RNA polymerase activity; [2.7.7.6] DNA-directed RNA polymerase.; [PF04560] RNA polymerase Rpb2, domain 7; [PF04563] RNA polymerase beta subunit 13.86 0.7766 9 Mapoly0118s0005 [GO:0008233] peptidase activity; [3.4.22.49] Separase.; [K02365] separase [EC:3.4.22.49]; [GO:0005634] nucleus; [PF03568] Peptidase family C50; [GO:0006508] proteolysis; [PTHR12792] EXTRA SPINDLE POLES 1-RELATED 14.70 0.8366 10 Mapoly0024s0112 [GO:0005643] nuclear pore; [KOG1964] Nuclear pore complex, rNup107 component (sc Nup84); [PTHR13003] NUP107-RELATED; [GO:0006810] transport; [PF04121] Nuclear pore protein 84 / 107; [K14301] nuclear pore complex protein Nup107 15.23 0.8153 11 Mapoly0042s0082 [GO:0005643] nuclear pore; [PF07926] TPR/MLP1/MLP2-like protein; [PTHR18898] NUCLEOPROTEIN TPR-RELATED; [K09291] nucleoprotein TPR; [KOG4674] Uncharacterized conserved coiled-coil protein; [GO:0006606] protein import into nucleus 15.87 0.8282 12 Mapoly0054s0064 [PF03178] CPSF A subunit region; [PF10433] Mono-functional DNA-alkylating methyl methanesulfonate N-term; [PTHR10644:SF3] DNA DAMAGE-BINDING PROTEIN 1 (DAMAGE-SPECIFIC DNA-BINDING PROTEIN 1)(UV-DAMAGED DNA-BINDING FACTOR); [K10610] DNA damage-binding protein 1; [GO:0005634] nucleus; [PTHR10644] DNA REPAIR/RNA PROCESSING CPSF FAMILY; [KOG1897] Damage-specific DNA binding complex, subunit DDB1; [GO:0003676] nucleic acid binding 16.61 0.7424 13 Mapoly0069s0028 [3.1.27.-] Endoribonucleases producing other than 5'-phosphomonoesters.; [PF07521] RNA-metabolising metallo-beta-lactamase; [PTHR11203] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF11718] Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term; [KOG1137] mRNA cleavage and polyadenylation factor II complex, BRR5 (CPSF subunit); [PF00753] Metallo-beta-lactamase superfamily; [K14403] cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]; [PF10996] Beta-Casp domain; [PTHR11203:SF32] UNCHARACTERIZED 16.88 0.7519 14 Mapoly0008s0107 [K12852] 116 kDa U5 small nuclear ribonucleoprotein component; [PF00009] Elongation factor Tu GTP binding domain; [PF00679] Elongation factor G C-terminus; [GO:0003924] GTPase activity; [PTHR23115] TRANSLATION FACTOR; [PTHR23115:SF5] 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT; [PF03764] Elongation factor G, domain IV; [KOG0468] U5 snRNP-specific protein; [GO:0005525] GTP binding; [PF03144] Elongation factor Tu domain 2 18.73 0.8134 15 Mapoly0078s0012 [GO:0006396] RNA processing; [PTHR11061] RNA M5U METHYLTRANSFERASE FAMILY; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0008173] RNA methyltransferase activity; [PF05958] tRNA (Uracil-5-)-methyltransferase; [GO:0046872] metal ion binding; [KOG2187] tRNA uracil-5-methyltransferase and related tRNA-modifying enzymes 20.90 0.7838 16 Mapoly0005s0051 [GO:0003723] RNA binding; [GO:0000339] RNA cap binding; [GO:0045292] mRNA cis splicing, via spliceosome; [GO:0051028] mRNA transport; [PF02854] MIF4G domain; [GO:0005515] protein binding; [KOG1104] Nuclear cap-binding complex, subunit NCBP1/CBP80; [K12882] nuclear cap-binding protein subunit 1; [GO:0016070] RNA metabolic process; [PTHR12412] CAP BINDING PROTEIN; [GO:0005846] nuclear cap binding complex; [PF09090] MIF4G like; [PF09088] MIF4G like 23.69 0.8066 17 Mapoly0011s0213 [PF13855] Leucine rich repeat; [KOG1187] Serine/threonine protein kinase; [PF13516] Leucine Rich repeat; [PF07714] Protein tyrosine kinase; [PF08263] Leucine rich repeat N-terminal domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PF12799] Leucine Rich repeats (2 copies); [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 24.49 0.7069 18 Mapoly0155s0010 [KOG0319] WD40-repeat-containing subunit of the 18S rRNA processing complex; [PF08625] Utp13 specific WD40 associated domain; [PTHR19854:SF15] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [GO:0006364] rRNA processing; [K14555] U3 small nucleolar RNA-associated protein 13; [GO:0032040] small-subunit processome; [PTHR19854] TRANSDUCIN BETA-LIKE 3; [PF00400] WD domain, G-beta repeat 28.64 0.7828 19 Mapoly0023s0084 [PTHR16056:SF2] TESTIS EXPRESSED GENE 10-RELATED; [PTHR16056] UNCHARACTERIZED; [PF12333] Rix1 complex component involved in 60S ribosome maturation 28.93 0.7742 20 Mapoly0025s0095 [GO:0003677] DNA binding; [GO:0003917] DNA topoisomerase type I activity; [PTHR11390:SF22] DNA TOPOISOMERASE I; [PF01751] Toprim domain; [PF13368] Topoisomerase C-terminal repeat; [GO:0006265] DNA topological change; [KOG1956] DNA topoisomerase III alpha; [PF01396] Topoisomerase DNA binding C4 zinc finger; [GO:0005694] chromosome; [GO:0003916] DNA topoisomerase activity; [PTHR11390] PROKARYOTIC DNA TOPOISOMERASE; [PF01131] DNA topoisomerase 30.03 0.7616 21 Mapoly0034s0031 [GO:0007094] mitotic spindle assembly checkpoint; [K06638] mitotic spindle assembly checkpoint protein MAD1; [KOG4593] Mitotic checkpoint protein MAD1; [PTHR23168] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 (MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1); [PF05557] Mitotic checkpoint protein; [PTHR23168:SF0] SUBFAMILY NOT NAMED 31.30 0.7956 22 Mapoly0001s0044 [PTHR31110] FAMILY NOT NAMED 32.86 0.7895 23 Mapoly0060s0046 [GO:0006396] RNA processing; [PTHR11246] PRE-MRNA SPLICING FACTOR; [KOG1915] Cell cycle control protein (crooked neck); [GO:0005515] protein binding; [PF13181] Tetratricopeptide repeat; [K12869] crooked neck; [GO:0005622] intracellular; [PF02184] HAT (Half-A-TPR) repeat; [PTHR11246:SF3] CROOKED NECK PROTEIN 33.94 0.7644 24 Mapoly0102s0024 [GO:0006355] regulation of transcription, DNA-dependent; [PF14443] DBC1; [KOG3227] Calcium-responsive transcription coactivator; [PTHR14304] P30 DBC PROTEIN 35.78 0.7929 25 Mapoly0131s0025 [PF08324] PUL domain; [KOG0301] Phospholipase A2-activating protein (contains WD40 repeats); [PTHR19849] PHOSPHOLIPASE A-2-ACTIVATING PROTEIN; [PTHR19849:SF0] SUBFAMILY NOT NAMED; [K14018] phospholipase A-2-activating protein; [GO:0005515] protein binding; [PF09070] PFU (PLAA family ubiquitin binding); [PF00400] WD domain, G-beta repeat 38.46 0.7239 26 Mapoly0033s0057 [2.3.1.-] Transferring groups other than amino-acyl groups.; [PTHR11076:SF1] ESTABLISHMENT OF COHESION 1 (ECO1) HOMOLOG; [PF13880] ESCO1/2 acetyl-transferase; [PF13878] zinc-finger of acetyl-transferase ESCO; [KOG3014] Protein involved in establishing cohesion between sister chromatids during DNA replication; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [K11268] N-acetyltransferase [EC:2.3.1.-] 38.83 0.7972 27 Mapoly0006s0290 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR10670:SF0] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A; [GO:0000166] nucleotide binding; [GO:0008270] zinc ion binding; [2.7.7.7] DNA-directed DNA polymerase.; [KOG1798] DNA polymerase epsilon, catalytic subunit A; [PF08490] Domain of unknown function (DUF1744); [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF00136] DNA polymerase family B; [GO:0008622] epsilon DNA polymerase complex; [K02324] DNA polymerase epsilon subunit 1 [EC:2.7.7.7]; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10670] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A 38.90 0.7902 28 Mapoly0001s0474 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [K11294] nucleolin; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 39.40 0.7185 29 Mapoly0005s0174 [GO:0005524] ATP binding; [KOG0933] Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E); [GO:0007076] mitotic chromosome condensation; [GO:0005515] protein binding; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0000796] condensin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PTHR18937:SF9] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC2; [K06674] structural maintenance of chromosome 2; [PF06470] SMC proteins Flexible Hinge Domain 40.40 0.7991 30 Mapoly0033s0024 [GO:0005524] ATP binding; [K14572] midasin; [PF07728] AAA domain (dynein-related subfamily); [GO:0016887] ATPase activity; [KOG1808] AAA ATPase containing von Willebrand factor type A (vWA) domain; [PTHR22908] MIDASIN-RELATED 41.41 0.7572 31 Mapoly0005s0056 [GO:0005524] ATP binding; [PTHR11752] HELICASE SKI2W; [KOG0947] Cytoplasmic exosomal RNA helicase SKI2, DEAD-box superfamily; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF08148] DSHCT (NUC185) domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [PF13234] rRNA-processing arch domain; [GO:0003676] nucleic acid binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [K12599] antiviral helicase SKI2 [EC:3.6.4.-] 41.95 0.7602 32 Mapoly0020s0107 [KOG4626] O-linked N-acetylglucosamine transferase OGT; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13432] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat; [PF13844] Glycosyl transferase family 41; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR 45.43 0.7579 33 Mapoly0002s0133 [GO:0007076] mitotic chromosome condensation; [PTHR13108] FAMILY NOT NAMED; [PF05786] Condensin complex subunit 2; [KOG2328] Chromosome condensation complex Condensin, subunit H; [GO:0000796] condensin complex; [K06676] condensin complex subunit 2 48.28 0.7794 34 Mapoly0010s0036 [KOG2002] TPR-containing nuclear phosphoprotein that regulates K(+) uptake; [PF07719] Tetratricopeptide repeat; [PTHR14027:SF2] TPR REPEAT NUCLEAR PHOSPHOPROTEIN; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13174] Tetratricopeptide repeat; [PF13181] Tetratricopeptide repeat; [PF13424] Tetratricopeptide repeat; [PTHR14027] TPR REPEAT NUCLEAR PHOSPHOPROTEIN/CTR9; [PF00515] Tetratricopeptide repeat 48.48 0.7755 35 Mapoly0079s0030 [KOG0543] FKBP-type peptidyl-prolyl cis-trans isomerase; [PTHR10516] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF13414] TPR repeat; [GO:0006457] protein folding; [PF00254] FKBP-type peptidyl-prolyl cis-trans isomerase 49.31 0.6691 36 Mapoly0007s0003 [GO:0005515] protein binding; [PTHR19918:SF8] gb def: Meiosis-specific APC/C activator protein AMA1 (Activator of meiotic APC/C protei; [KOG0305] Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits; [K03363] cell division cycle 20, cofactor of APC complex; [PTHR19918] CELL DIVISION CYCLE 20 (CDC20) (FIZZY)-RELATED; [PF00400] WD domain, G-beta repeat 50.16 0.7654 37 Mapoly0081s0047 [PF00773] RNB domain; [PF13638] PIN domain; [3.1.13.-] Exoribonucleases producing 5'-phosphomonoesters.; [K12585] exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]; [PTHR23355] RIBONUCLEASE; [KOG2102] Exosomal 3'-5' exoribonuclease complex, subunit Rrp44/Dis3 52.80 0.7430 38 Mapoly0016s0130 [PF14817] HAUS augmin-like complex subunit 5; [GO:0051225] spindle assembly 53.58 0.7672 39 Mapoly0042s0123 [K12875] apoptotic chromatin condensation inducer in the nucleus; [GO:0003676] nucleic acid binding; [PTHR14127] APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; [PF02037] SAP domain 54.44 0.7743 40 Mapoly0001s0449 [GO:0006355] regulation of transcription, DNA-dependent; [PF04153] NOT2 / NOT3 / NOT5 family; [GO:0005634] nucleus; [K12605] CCR4-NOT transcription complex subunit 2; [PTHR23326] CCR4 NOT-RELATED 55.10 0.7001 41 Mapoly0032s0119 [GO:0007076] mitotic chromosome condensation; [K06678] condensin complex subunit 3; [GO:0000796] condensin complex; [PTHR14418] CONDENSIN COMPLEX SUBUNIT 3-RELATED; [PF12719] Nuclear condensing complex subunits, C-term domain 55.10 0.7791 42 Mapoly0033s0098 [PTHR16047] RFWD3 PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PTHR16047:SF7] RFWD3 PROTEIN-RELATED; [KOG1645] RING-finger-containing E3 ubiquitin ligase 55.64 0.7606 43 Mapoly0023s0143 [GO:0005524] ATP binding; [PTHR23073] 26S PROTEASE REGULATORY SUBUNIT; [PTHR23073:SF18] SUBFAMILY NOT NAMED; [PF00004] ATPase family associated with various cellular activities (AAA) 56.12 0.7647 44 Mapoly0069s0022 [PF04097] Nup93/Nic96; [GO:0005643] nuclear pore; [KOG2168] Cullins; [PTHR11225] NUCLEAR PORE COMPLEX PROTEIN NUP93 (NUCLEOPORIN NUP93) (DEAD EYE PROTEIN); [K14309] nuclear pore complex protein Nup93; [GO:0006810] transport 58.03 0.7641 45 Mapoly0030s0009 [PF00505] HMG (high mobility group) box; [KOG0526] Nucleosome-binding factor SPN, POB3 subunit; [PF03531] Structure-specific recognition protein (SSRP1); [PTHR13711:SF39] SUBFAMILY NOT NAMED; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [PF08512] Histone chaperone Rttp106-like; [K09272] structure-specific recognition protein 1 59.37 0.7595 46 Mapoly0209s0008 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF67] DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 60.09 0.7783 47 Mapoly0001s0188 - 61.48 0.7697 48 Mapoly0094s0016 [KOG4674] Uncharacterized conserved coiled-coil protein 62.23 0.7674 49 Mapoly0060s0012 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [K11498] centromeric protein E; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 63.49 0.7721 50 Mapoly0162s0013 [PF00929] Exonuclease; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [PTHR11361:SF34] DNA MISMATCH REPAIR PROTEIN MUTS; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [KOG0218] Mismatch repair MSH3; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 64.16 0.7610 51 Mapoly0003s0057 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination 66.30 0.7728 52 Mapoly0020s0135 [PF03941] Inner centromere protein, ARK binding region; [PTHR13142:SF1] INCENP; [KOG1295] Nonsense-mediated decay protein Upf3; [PTHR13142] INNER CENTROMERE PROTEIN 66.58 0.7688 53 Mapoly0105s0035 [PTHR12341] 5'-3' EXORIBONUCLEASE; [PF03159] XRN 5'-3' exonuclease N-terminus; [K12619] 5'-3' exoribonuclease 2 [EC:3.1.13.-]; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [3.1.13.-] Exoribonucleases producing 5'-phosphomonoesters.; [GO:0003676] nucleic acid binding; [GO:0004527] exonuclease activity 67.08 0.7600 54 Mapoly0072s0051 [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [KOG0597] Serine-threonine protein kinase FUSED; [GO:0006468] protein phosphorylation 69.74 0.7640 55 Mapoly0029s0111 [PTHR22836] WD40 REPEAT PROTEIN; [GO:0005515] protein binding; [KOG0284] Polyadenylation factor I complex, subunit PFS2; [PF00400] WD domain, G-beta repeat 70.15 0.6997 56 Mapoly0089s0007 [PF04821] Timeless protein; [PTHR22940:SF4] GB DEF: ARABIDOPSIS THALIANA GENOMIC DNA, CHROMOSOME 5, P1 CLONE:MXC20; [PF05029] Timeless protein C terminal region; [K03155] timeless; [KOG1974] DNA topoisomerase I-interacting protein; [PTHR22940] TIMEOUT/TIMELESS-2 72.07 0.7146 57 Mapoly0013s0191 [K13526] cation-transporting ATPase 13A2 [EC:3.6.3.-]; [GO:0000166] nucleotide binding; [PF00702] haloacid dehalogenase-like hydrolase; [3.6.3.-] Acting on acid anhydrides; catalyzing transmembrane movement of substances.; [PTHR24093] FAMILY NOT NAMED; [PF00690] Cation transporter/ATPase, N-terminus; [GO:0046872] metal ion binding; [KOG0208] Cation transport ATPase; [PF00122] E1-E2 ATPase; [PTHR24093:SF84] CATION-TRANSPORTING P-TYPE ATPASE 72.55 0.7106 58 Mapoly0014s0197 [KOG4822] Predicted nuclear membrane protein involved in mRNA transport and sex determination via splicing modulation; [PTHR23185:SF0] SUBFAMILY NOT NAMED; [PTHR23185] UNCHARACTERIZED 75.30 0.7543 59 Mapoly0032s0034 - 75.72 0.7474 60 Mapoly0098s0043 [PF12717] non-SMC mitotic condensation complex subunit 1; [GO:0007076] mitotic chromosome condensation; [K11491] condensin-2 complex subunit D3; [PTHR14222:SF1] CONDENSIN; [PTHR14222] CONDENSIN 77.20 0.7621 61 Mapoly0097s0045 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11752] HELICASE SKI2W; [2.7.7.7] DNA-directed DNA polymerase.; [K02349] DNA polymerase theta subunit [EC:2.7.7.7]; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF00476] DNA polymerase family A; [GO:0003676] nucleic acid binding; [GO:0003887] DNA-directed DNA polymerase activity; [KOG0950] DNA polymerase theta/eta, DEAD-box superfamily 78.49 0.7307 62 Mapoly0022s0121 - 79.39 0.7599 63 Mapoly0001s0391 [GO:0005634] nucleus; [PF05965] F/Y rich C-terminus 79.45 0.7484 64 Mapoly0001s0208 [PTHR31431] FAMILY NOT NAMED; [KOG4833] Uncharacterized conserved protein; [K14311] nuclear pore complex protein Nup188; [PF10487] Nucleoporin subcomplex protein binding to Pom34 80.16 0.7468 65 Mapoly0073s0063 [GO:0016020] membrane; [GO:0005524] ATP binding; [GO:0017038] protein import; [PF07516] SecA Wing and Scaffold domain; [PTHR30612] SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM; [PF07517] SecA DEAD-like domain; [PF01043] SecA preprotein cross-linking domain; [K03070] preprotein translocase subunit SecA 83.11 0.6397 66 Mapoly0011s0202 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain 84.71 0.7639 67 Mapoly0005s0093 [KOG1883] Cofactor required for Sp1 transcriptional activation, subunit 3; [PF11573] Mediator complex subunit 23; [PTHR12691] FAMILY NOT NAMED 85.17 0.7203 68 Mapoly0023s0118 [PTHR12446] TESMIN/TSO1-RELATED; [PF03638] Tesmin/TSO1-like CXC domain, cysteine-rich domain 87.91 0.7522 69 Mapoly0042s0023 [GO:0005524] ATP binding; [2.7.12.1] Dual-specificity kinase.; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [K08866] serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]; [PTHR22974] MIXED LINEAGE PROTEIN KINASE 88.60 0.7568 70 Mapoly0025s0127 - 88.72 0.7451 71 Mapoly0013s0059 [GO:0005515] protein binding; [PF02213] GYF domain; [PTHR14445] GRB10 INTERACTING GYF PROTEIN 89.36 0.7444 72 Mapoly0039s0062 [GO:0005524] ATP binding; [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [GO:0003676] nucleic acid binding; [KOG0922] DEAH-box RNA helicase; [PF07717] Oligonucleotide/oligosaccharide-binding (OB)-fold 89.80 0.7028 73 Mapoly0102s0001 [K06228] fused [EC:2.7.11.1]; [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR22983:SF6] MAPK KINASE 2-RELATED; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [KOG0598] Ribosomal protein S6 kinase and related proteins; [PF13646] HEAT repeats 90.34 0.7544 74 Mapoly0122s0062 [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 90.61 0.7558 75 Mapoly0135s0025 [PF13513] HEAT-like repeat; [GO:0005515] protein binding; [PTHR23346] TRANSLATIONAL ACTIVATOR GCN1-RELATED; [PF02985] HEAT repeat; [PTHR23346:SF7] TRANSLATIONAL ACTIVATOR GCN1-RELATED; [PF12074] Domain of unknown function (DUF3554); [KOG1242] Protein containing adaptin N-terminal region; [PF13646] HEAT repeats 93.05 0.7125 76 Mapoly0153s0002 [GO:0005524] ATP binding; [GO:0000166] nucleotide binding; [PF08264] Anticodon-binding domain of tRNA; [6.1.1.4] Leucine--tRNA ligase.; [PTHR11946] ISOLEUCYL, LEUCYL, TYROSYL, VALYL AND METHIONYL-TRNA SYNTHETASES; [K01869] leucyl-tRNA synthetase [EC:6.1.1.4]; [PF00133] tRNA synthetases class I (I, L, M and V); [KOG0437] Leucyl-tRNA synthetase; [GO:0006418] tRNA aminoacylation for protein translation; [GO:0004812] aminoacyl-tRNA ligase activity 93.22 0.7311 77 Mapoly0045s0061 [KOG1081] Transcription factor NSD1 and related SET domain proteins; [GO:0005515] protein binding; [PF00856] SET domain; [PTHR22884] SET DOMAIN PROTEINS 93.83 0.7400 78 Mapoly0032s0121 [PTHR22976] BIOTIN SYNTHASE; [PTHR22976:SF4] SUBFAMILY NOT NAMED; [PF04055] Radical SAM superfamily; [GO:0003824] catalytic activity; [GO:0051536] iron-sulfur cluster binding 94.51 0.6752 79 Mapoly0004s0169 [GO:0003677] DNA binding; [GO:0006338] chromatin remodeling; [GO:0005524] ATP binding; [PF09110] HAND; [K11654] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]; [GO:0043044] ATP-dependent chromatin remodeling; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [GO:0005634] nucleus; [PTHR10799:SF73] ISWI CHROMATIN-REMODELING COMPLEX ATPASE ISW1; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [KOG0385] Chromatin remodeling complex WSTF-ISWI, small subunit; [GO:0003676] nucleic acid binding; [GO:0031491] nucleosome binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [PF09111] SLIDE 96.75 0.7445 80 Mapoly0043s0047 [GO:0005515] protein binding; [PF00612] IQ calmodulin-binding motif; [PTHR25069] FAMILY NOT NAMED; [PF00307] Calponin homology (CH) domain 98.12 0.7500 81 Mapoly0107s0034 [3.5.1.98] Histone deacetylase.; [KOG1342] Histone deacetylase complex, catalytic component RPD3; [K06067] histone deacetylase 1/2 [EC:3.5.1.98]; [PF00850] Histone deacetylase domain; [PTHR10625] HISTONE DEACETYLASE 98.95 0.7186 82 Mapoly0051s0073 [PF14675] FANCI solenoid 1; [PTHR21818:SF0] SUBFAMILY NOT NAMED; [PF14680] FANCI helical domain 2; [KOG4553] Uncharacterized conserved protein; [K10895] fanconi anemia group I protein; [PF14679] FANCI helical domain 1; [GO:0006281] DNA repair; [PF14678] FANCI solenoid 4; [PTHR21818] BC025462 PROTEIN; [PF14676] FANCI solenoid 2 99.50 0.7368 83 Mapoly0085s0026 [PF00533] BRCA1 C Terminus (BRCT) domain; [PTHR23196] PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN 99.60 0.7469 84 Mapoly0035s0137 [GO:0005643] nuclear pore; [PTHR10350:SF6] NUCLEOPORIN 155; [PF03177] Non-repetitive/WGA-negative nucleoporin C-terminal; [K14312] nuclear pore complex protein Nup155; [KOG1900] Nuclear pore complex, Nup155 component (D Nup154, sc Nup157/Nup170); [GO:0006913] nucleocytoplasmic transport; [PF08801] Nup133 N terminal like; [GO:0017056] structural constituent of nuclear pore; [PTHR10350] NUCLEAR PORE COMPLEX PROTEIN NUP155 100.40 0.7475 85 Mapoly0140s0032 [PTHR12748] ORIGIN RECOGNITION COMPLEX SUBUNIT 3; [PTHR12748:SF0] SUBFAMILY NOT NAMED; [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02605] origin recognition complex subunit 3; [PF07034] Origin recognition complex (ORC) subunit 3 N-terminus; [KOG2538] Origin recognition complex, subunit 3; [GO:0005664] nuclear origin of replication recognition complex; [PF02178] AT hook motif 100.87 0.7530 86 Mapoly0057s0017 - 101.11 0.7387 87 Mapoly0034s0119 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 102.74 0.7547 88 Mapoly0009s0141 [PF05022] SRP40, C-terminal domain; [PTHR23216] NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 103.29 0.7281 89 Mapoly0130s0046 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF14493] Helix-turn-helix domain; [PF09382] RQC domain; [K10900] werner syndrome ATP-dependent helicase [EC:3.6.4.12]; [KOG0353] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 105.24 0.7338 90 Mapoly0038s0027 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PTHR10629:SF11] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF12047] Cytosine specific DNA methyltransferase replication foci domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 107.00 0.7142 91 Mapoly0021s0013 [PTHR19853] WD REPEAT CONTAINING PROTEIN 3 (WDR3); [GO:0005515] protein binding; [PF04003] Dip2/Utp12 Family; [KOG0306] WD40-repeat-containing subunit of the 18S rRNA processing complex; [PTHR19853:SF0] SUBFAMILY NOT NAMED; [K14556] U3 small nucleolar RNA-associated protein 12; [PF00400] WD domain, G-beta repeat 109.70 0.7282 92 Mapoly0097s0064 [PTHR13710:SF1] ROTHMUND-THOMSON SYNDROME DNA HELICASE RECQ4; [GO:0005524] ATP binding; [PF11719] DNA replication and checkpoint protein; [K10730] ATP-dependent DNA helicase Q4 [EC:3.6.4.12]; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [GO:0003676] nucleic acid binding; [PF02037] SAP domain 111.07 0.7375 93 Mapoly0047s0105 [KOG4308] LRR-containing protein; [PTHR10098] RAPSYN-RELATED; [PF13516] Leucine Rich repeat; [PF13414] TPR repeat 112.05 0.7298 94 Mapoly0070s0053 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF09382] RQC domain; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [K10901] bloom syndrome protein [EC:3.6.4.12]; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 112.72 0.7349 95 Mapoly0019s0008 [GO:0003723] RNA binding; [PF10596] U6-snRNA interacting domain of PrP8; [PF08083] PROCN (NUC071) domain; [GO:0005515] protein binding; [GO:0005681] spliceosomal complex; [PTHR11140] PRE-MRNA SPLICING FACTOR PRP8; [PTHR11140:SF0] SUBFAMILY NOT NAMED; [PF01398] JAB1/Mov34/MPN/PAD-1 ubiquitin protease; [GO:0030623] U5 snRNA binding; [PF10597] U5-snRNA binding site 2 of PrP8; [KOG1795] U5 snRNP spliceosome subunit; [GO:0000398] mRNA splicing, via spliceosome; [PF12134] PRP8 domain IV core; [PF10598] RNA recognition motif of the spliceosomal PrP8; [K12856] pre-mRNA-processing factor 8; [GO:0017070] U6 snRNA binding; [PF08082] PRO8NT (NUC069), PrP8 N-terminal domain; [PF08084] PROCT (NUC072) domain 113.01 0.7180 96 Mapoly0010s0026 [GO:0006357] regulation of transcription from RNA polymerase II promoter; [PTHR13114] TRANSCRIPTIONAL CO-ACTIVATOR CRSP77-RELATED; [PF10156] Subunit 17 of Mediator complex; [GO:0001104] RNA polymerase II transcription cofactor activity; [GO:0016592] mediator complex 113.13 0.6631 97 Mapoly0013s0006 [GO:0008270] zinc ion binding; [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PTHR23336] ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3.; [PF07496] CW-type Zinc Finger 113.49 0.7099 98 Mapoly0044s0071 [PTHR12827] MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; [PF12859] Anaphase-promoting complex subunit 1; [K03348] anaphase-promoting complex subunit 1; [KOG1858] Anaphase-promoting complex (APC), subunit 1 (meiotic check point regulator/Tsg24); [GO:0005680] anaphase-promoting complex 113.89 0.7070 99 Mapoly0113s0048 [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [KOG1408] WD40 repeat protein; [PF00400] WD domain, G-beta repeat 114.59 0.7443 100 Mapoly0015s0081 [PF11707] Ribosome 60S biogenesis N-terminal; [PTHR13500] NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1 116.69 0.7368 101 Mapoly0005s0138 - 117.12 0.7142 102 Mapoly0027s0041 [GO:0005643] nuclear pore; [PTHR13437] NUCLEOPORIN P58/P45 (NUCLEOPORIN-LIKE PROTEIN 1); [GO:0006913] nucleocytoplasmic transport 117.15 0.7199 103 Mapoly0036s0123 [GO:0000922] spindle pole; [PTHR19302:SF13] GAMMA-TUBULIN COMPLEX COMPONENT 2 (GCP-2); [PF04130] Spc97 / Spc98 family; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [KOG2001] Gamma-tubulin complex, DGRIP84/SPC97 component 118.03 0.7408 104 Mapoly0063s0085 [KOG3655] Drebrins and related actin binding proteins; [PF04548] AIG1 family; [PTHR10903] GTPASE, IMAP FAMILY MEMBER-RELATED; [PF11886] Domain of unknown function (DUF3406); [GO:0005525] GTP binding 118.26 0.6684 105 Mapoly0005s0127 - 119.21 0.7181 106 Mapoly0005s0221 [GO:0005643] nuclear pore; [PTHR12084] NUCLEAR PORE GLYCOPROTEIN P62-RELATED; [KOG2196] Nuclear porin; [PTHR12084:SF0] SUBFAMILY NOT NAMED; [K14306] nuclear pore complex protein Nup62; [PF05064] Nsp1-like C-terminal region; [GO:0017056] structural constituent of nuclear pore 120.51 0.7155 107 Mapoly0043s0081 [GO:0005524] ATP binding; [PF02889] Sec63 Brl domain; [PTHR11752] HELICASE SKI2W; [3.6.4.13] RNA helicase.; [PF00270] DEAD/DEAH box helicase; [PTHR11752:SF7] U520; [PF00271] Helicase conserved C-terminal domain; [KOG0951] RNA helicase BRR2, DEAD-box superfamily; [GO:0003676] nucleic acid binding; [K12854] pre-mRNA-splicing helicase BRR2 [EC:3.6.4.13] 120.96 0.7085 108 Mapoly0063s0058 [PF02170] PAZ domain; [PF08699] Domain of unknown function (DUF1785); [PTHR22891] EUKARYOTIC TRANSLATION INITIATION FACTOR 2C; [PF02171] Piwi domain; [GO:0005515] protein binding; [KOG1041] Translation initiation factor 2C (eIF-2C) and related proteins 121.47 0.4707 109 Mapoly0002s0169 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [K06632] wee1-like protein kinase [EC:2.7.11.1]; [PTHR11042] EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE (EIF2-ALPHA KINASE)-RELATED; [KOG0601] Cyclin-dependent kinase WEE1 122.28 0.7222 110 Mapoly0003s0120 [GO:0003677] DNA binding; [PTHR12708:SF0] SUBFAMILY NOT NAMED; [GO:0006260] DNA replication; [PF12213] DNA polymerases epsilon N terminal; [2.7.7.7] DNA-directed DNA polymerase.; [PTHR12708] DNA POLYMERASE EPSILON SUBUNIT B; [KOG3818] DNA polymerase epsilon, subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [GO:0003887] DNA-directed DNA polymerase activity; [K02325] DNA polymerase epsilon subunit 2 [EC:2.7.7.7] 123.65 0.7128 111 Mapoly0004s0202 - 124.04 0.7264 112 Mapoly0001s0076 [PF00225] Kinesin motor domain; [GO:0007018] microtubule-based movement; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0008017] microtubule binding; [KOG4280] Kinesin-like protein; [PF06548] Kinesin-related; [GO:0003777] microtubule motor activity; [GO:0005871] kinesin complex 126.21 0.7229 113 Mapoly0116s0041 [PF13297] Telomere stability C-terminal; [PTHR12786:SF2] SPLICING FACTOR 3A; [PF12108] Splicing factor SF3a60 binding domain; [KOG2636] Splicing factor 3a, subunit 3; [PTHR12786] SPLICING FACTOR SF3A-RELATED; [K12827] splicing factor 3A subunit 3; [PF11931] Domain of unknown function (DUF3449) 129.75 0.7214 114 Mapoly0151s0038 [GO:0016020] membrane; [GO:0055085] transmembrane transport; [KOG4629] Predicted mechanosensitive ion channel; [PTHR31618] FAMILY NOT NAMED; [PF00924] Mechanosensitive ion channel 131.34 0.6659 115 Mapoly0025s0106 [PF14635] Helix-hairpin-helix motif; [GO:0003677] DNA binding; [PTHR10145:SF6] TRANSCRIPTION ELONGATION FACTOR SPT6-RELATED; [PF14641] Helix-turn-helix DNA-binding domain of SPT6; [GO:0006357] regulation of transcription from RNA polymerase II promoter; [GO:0005515] protein binding; [PF14633] SH2 domain; [PF14639] Holliday-junction resolvase-like of SPT6; [PF14878] Death-like domain of SPT6; [GO:0032784] regulation of DNA-dependent transcription, elongation; [PF14632] Acidic N-terminal SPT6; [K11292] transcription elongation factor SPT6; [KOG1856] Transcription elongation factor SPT6; [PTHR10145] TRANSCRIPTION ELONGATION FACTOR SPT6 132.78 0.7296 116 Mapoly0075s0033 - 132.79 0.7350 117 Mapoly0074s0043 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [GO:0003729] mRNA binding 132.82 0.7151 118 Mapoly0033s0145 - 134.04 0.7105 119 Mapoly0125s0021 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR23273:SF0] SUBFAMILY NOT NAMED; [GO:0008270] zinc ion binding; [PF04057] Replication factor-A protein 1, N-terminal domain; [PF00098] Zinc knuckle; [GO:0005634] nucleus; [PF08646] Replication factor-A C terminal domain; [GO:0003676] nucleic acid binding; [K07466] replication factor A1; [PTHR23273] REPLICATION FACTOR A 1, RFA1; [PF01336] OB-fold nucleic acid binding domain 134.39 0.6712 120 Mapoly0014s0207 [PTHR14212] U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED; [GO:0046540] U4/U6 x U5 tri-snRNP complex; [K12843] U4/U6 small nuclear ribonucleoprotein PRP3; [GO:0000398] mRNA splicing, via spliceosome; [KOG2769] Putative u4/u6 small nuclear ribonucleoprotein; [PF06544] Protein of unknown function (DUF1115); [PF08572] pre-mRNA processing factor 3 (PRP3) 134.71 0.7259 121 Mapoly0026s0077 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [2.7.11.1] Non-specific serine/threonine protein kinase.; [PF08064] UME (NUC010) domain; [PF00454] Phosphatidylinositol 3- and 4-kinase; [K06640] ataxia telangiectasia and Rad3 related [EC:2.7.11.1]; [GO:0004674] protein serine/threonine kinase activity; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [KOG0890] Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination 135.09 0.7037 122 Mapoly0013s0201 [PTHR23269:SF0] SUBFAMILY NOT NAMED; [KOG0128] RNA-binding protein SART3 (RRM superfamily); [PF05391] Lsm interaction motif; [GO:0003676] nucleic acid binding; [PTHR23269] RIBONUCLEOPROTEIN-RELATED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 137.98 0.7102 123 Mapoly0001s0525 [K14408] cleavage stimulation factor subunit 3; [GO:0006397] mRNA processing; [GO:0005634] nucleus; [KOG1914] mRNA cleavage and polyadenylation factor I complex, subunit RNA14; [PTHR19980] RNA CLEAVAGE STIMULATION FACTOR; [PF05843] Suppressor of forked protein (Suf) 139.21 0.7192 124 Mapoly0074s0025 [PTHR12933] ORF PROTEIN-RELATED; [PF06862] Protein of unknown function (DUF1253); [KOG2340] Uncharacterized conserved protein; [GO:0005634] nucleus 144.29 0.5998 125 Mapoly0059s0004 - 145.54 0.6627 126 Mapoly0080s0038 [PTHR14005:SF0] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [KOG2072] Translation initiation factor 3, subunit a (eIF-3a); [PF01399] PCI domain; [PTHR14005] EUKARYOTIC TRANSLATION INITIATION FACTOR 3, THETA SUBUNIT; [K03254] translation initiation factor eIF-3 subunit 10; [GO:0005852] eukaryotic translation initiation factor 3 complex 146.91 0.7134 127 Mapoly0031s0153 [2.3.1.-] Transferring groups other than amino-acyl groups.; [PTHR10925] N-ACETYLTRANSFERASE 10; [GO:0008080] N-acetyltransferase activity; [K14521] N-acetyltransferase 10 [EC:2.3.1.-]; [PF13725] Possible tRNA binding domain; [PF13718] GNAT acetyltransferase 2; [PF05127] Helicase; [PF08351] Domain of unknown function (DUF1726); [KOG2036] Predicted P-loop ATPase fused to an acetyltransferase 148.19 0.7219 128 Mapoly0022s0167 [PF12717] non-SMC mitotic condensation complex subunit 1; [PF12922] non-SMC mitotic condensation complex subunit 1, N-term; [GO:0007076] mitotic chromosome condensation; [PTHR14222] CONDENSIN; [KOG0414] Chromosome condensation complex Condensin, subunit D2; [K06677] condensin complex subunit 1 148.84 0.7154 129 Mapoly0074s0003 [GO:0003677] DNA binding; [PF12254] DNA polymerase alpha subunit p180 N terminal; [GO:0006260] DNA replication; [GO:0001882] nucleoside binding; [K02320] DNA polymerase alpha subunit A [EC:2.7.7.7]; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0006270] DNA replication initiation; [PF08996] DNA Polymerase alpha zinc finger; [KOG0970] DNA polymerase alpha, catalytic subunit; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT 149.36 0.6966 130 Mapoly0005s0161 [GO:0003677] DNA binding; [PTHR13451:SF0] SUBFAMILY NOT NAMED; [3.1.22.-] Endodeoxyribonucleases producing other than 5'-phosphomonoesters.; [K08991] crossover junction endonuclease MUS81 [EC:3.1.22.-]; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PF02732] ERCC4 domain 149.88 0.6775 131 Mapoly0080s0034 [2.1.1.43] Histone-lysine N-methyltransferase.; [KOG1082] Histone H3 (Lys9) methyltransferase SUV39H1/Clr4, required for transcriptional silencing; [K11419] histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43]; [PF05033] Pre-SET motif; [GO:0005515] protein binding; [PF00856] SET domain; [GO:0008270] zinc ion binding; [GO:0018024] histone-lysine N-methyltransferase activity; [PTHR22884] SET DOMAIN PROTEINS; [GO:0005634] nucleus; [GO:0034968] histone lysine methylation; [PF13771] PHD-like zinc-binding domain 150.40 0.6959 132 Mapoly0042s0049 - 150.48 0.7158 133 Mapoly0048s0100 [PTHR18937:SF8] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC3; [GO:0005524] ATP binding; [KOG0964] Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3); [GO:0008280] cohesin core heterodimer; [GO:0005515] protein binding; [GO:0003682] chromatin binding; [GO:0007064] mitotic sister chromatid cohesion; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain; [K06669] structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) 151.25 0.7057 134 Mapoly0004s0300 [GO:0005524] ATP binding; [PTHR11909:SF7] CELL DIVISION CONTROL PROTEIN 7; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K02214] cell division control protein 7 [EC:2.7.11.1]; [KOG1167] Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination; [GO:0006468] protein phosphorylation; [PTHR11909] CASEIN KINASE-RELATED 151.75 0.7172 135 Mapoly0064s0049 [PTHR19321:SF5] PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED; [GO:0000226] microtubule cytoskeleton organization; [GO:0000910] cytokinesis; [GO:0008017] microtubule binding; [PF03999] Microtubule associated protein (MAP65/ASE1 family); [KOG4302] Microtubule-associated protein essential for anaphase spindle elongation; [PTHR19321] PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED 151.82 0.6764 136 Mapoly0010s0012 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF06461] Domain of Unknown Function (DUF1086); [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00176] SNF2 family N-terminal domain; [PF06465] Domain of Unknown Function (DUF1087); [3.6.4.12] DNA helicase.; [PF00271] Helicase conserved C-terminal domain; [K11643] chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12]; [KOG0384] Chromodomain-helicase DNA-binding protein 151.96 0.7214 137 Mapoly0011s0104 [GO:0003755] peptidyl-prolyl cis-trans isomerase activity; [PTHR11071] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF00160] Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; [GO:0000413] protein peptidyl-prolyl isomerization; [KOG0546] HSP90 co-chaperone CPR7/Cyclophilin; [GO:0006457] protein folding 153.08 0.6697 138 Mapoly0002s0297 [PTHR11731] PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; [KOG2100] Dipeptidyl aminopeptidase; [GO:0008236] serine-type peptidase activity; [PF07676] WD40-like Beta Propeller Repeat; [GO:0006508] proteolysis; [PF00326] Prolyl oligopeptidase family 154.48 0.6798 139 Mapoly0081s0071 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [PF00628] PHD-finger; [GO:0005515] protein binding; [PF12738] twin BRCT domain; [GO:0046872] metal ion binding 154.87 0.7094 140 Mapoly0158s0032 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [K10728] topoisomerase (DNA) II binding protein 1; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 157.42 0.6818 141 Mapoly0001s0406 [GO:0000922] spindle pole; [KOG2000] Gamma-tubulin complex, DGRIP91/SPC98 component; [PF04130] Spc97 / Spc98 family; [GO:0005856] cytoskeleton; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [GO:0007020] microtubule nucleation; [PTHR19302:SF14] GAMMA-TUBULIN COMPLEX COMPONENT 3 (GCP-3) 157.53 0.6825 142 Mapoly0069s0034 [K14564] nucleolar protein 56; [PF01798] Putative snoRNA binding domain; [PTHR10894:SF0] NUCLEOLAR PROTEIN 5 (NUCLEOLAR PROTEIN NOP5)(NOP58); [PF08060] NOSIC (NUC001) domain; [PF08156] NOP5NT (NUC127) domain; [KOG2573] Ribosome biogenesis protein - Nop56p/Sik1p; [PTHR10894] NUCLEOLAR PROTEIN 5 (NUCLEOLAR PROTEIN NOP5)(NOP58) 158.48 0.6991 143 Mapoly0137s0008 [PF06278] Protein of unknown function (DUF1032); [PTHR14324] FAMILY NOT NAMED; [PTHR14324:SF3] SUBFAMILY NOT NAMED; [K11490] condensin-2 complex subunit H2; [KOG2359] Uncharacterized conserved protein 160.30 0.6953 144 Mapoly0127s0019 - 160.80 0.7013 145 Mapoly0042s0086 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K08737] DNA mismatch repair protein MSH6; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PTHR11361:SF31] MUTS HOMOLOG 6, MSH6; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 161.34 0.6991 146 Mapoly0148s0007 [GO:0016020] membrane; [PTHR12741] LYST-INTERACTING PROTEIN LIP5 (DOPAMINE RESPONSIVE PROTEIN DRG-1); [PF02364] 1,3-beta-glucan synthase component; [GO:0006075] (1-3)-beta-D-glucan biosynthetic process; [KOG0916] 1,3-beta-glucan synthase/callose synthase catalytic subunit; [GO:0000148] 1,3-beta-D-glucan synthase complex; [PF14288] 1,3-beta-glucan synthase subunit FKS1, domain-1; [K11000] callose synthase [EC:2.4.1.-]; [GO:0003843] 1,3-beta-D-glucan synthase activity; [PTHR12741:SF8] gb def: CG7967-PA (GH19706p) (RH70193p); [2.4.1.-] Hexosyltransferases. 163.50 0.6869 147 Mapoly0117s0005 [K13109] IK cytokine; [PTHR12765] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [KOG2498] IK cytokine down-regulator of HLA class II; [PF07807] RED-like protein C-terminal region; [PTHR12765:SF5] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [GO:0005634] nucleus; [PF07808] RED-like protein N-terminal region 163.77 0.6946 148 Mapoly0051s0016 [PF13831] PHD-finger; [PF05964] F/Y-rich N-terminus; [GO:0005515] protein binding; [PF13832] PHD-zinc-finger like domain; [PF00856] SET domain; [PTHR13793] PHD FINGER PROTEINS; [PF00855] PWWP domain; [GO:0005634] nucleus; [PF05965] F/Y rich C-terminus 164.05 0.7096 149 Mapoly0067s0095 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF13516] Leucine Rich repeat; [PF08263] Leucine rich repeat N-terminal domain; [PF00069] Protein kinase domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PF12799] Leucine Rich repeats (2 copies); [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 165.34 0.6136 150 Mapoly0148s0008 [K01754] threonine dehydratase [EC:4.3.1.19]; [PF00585] C-terminal regulatory domain of Threonine dehydratase; [4.3.1.19] Threonine ammonia-lyase.; [PF00291] Pyridoxal-phosphate dependent enzyme; [KOG1250] Threonine/serine dehydratases; [PTHR10314:SF30] THREONINE DEHYDRATASE; [PTHR10314] SER/THR DEHYDRATASE, TRP SYNTHASE 165.65 0.6768 151 Mapoly0024s0061 [KOG1508] DNA replication factor/protein phosphatase inhibitor SET/SPR-2; [PF00956] Nucleosome assembly protein (NAP); [GO:0005634] nucleus; [GO:0006334] nucleosome assembly; [K11290] template-activating factor I; [PTHR11875] TESTIS-SPECIFIC Y-ENCODED PROTEIN 165.86 0.7003 152 Mapoly0054s0075 [PTHR17695] UNCHARACTERIZED; [PTHR17695:SF11] SUBFAMILY NOT NAMED; [PF07539] Down-regulated in metastasis; [KOG1823] DRIM (Down-regulated in metastasis)-like proteins 166.10 0.7067 153 Mapoly0029s0003 [KOG1824] TATA-binding protein-interacting protein; [PTHR12696] TIP120; [PF08623] TATA-binding protein interacting (TIP20); [PF13646] HEAT repeats 166.16 0.6992 154 Mapoly0039s0120 [KOG1805] DNA replication helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PTHR10887:SF14] DNA2-LIKE HELICASE; [3.6.4.12] DNA helicase.; [PF13086] AAA domain; [GO:0033567] DNA replication, Okazaki fragment processing; [PF01930] Domain of unknown function DUF83; [GO:0017108] 5'-flap endonuclease activity; [GO:0043142] single-stranded DNA-dependent ATPase activity; [PF13087] AAA domain; [PF08696] DNA replication factor Dna2; [K10742] DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12] 166.49 0.6816 155 Mapoly0015s0055 [GO:0016020] membrane; [K10999] cellulose synthase A [EC:2.4.1.12]; [PF14569] Zinc-binding RING-finger; [2.4.1.12] Cellulose synthase (UDP-forming).; [PTHR13301] X-BOX TRANSCRIPTION FACTOR-RELATED; [GO:0016760] cellulose synthase (UDP-forming) activity; [GO:0030244] cellulose biosynthetic process; [PF03552] Cellulose synthase 168.37 0.6724 156 Mapoly0056s0030 [KOG1040] Polyadenylation factor I complex, subunit, Yth1 (CPSF subunit); [PTHR12357] YTH (YT521-B HOMOLOGY) DOMAIN-CONTAINING; [PF04146] YT521-B-like domain; [PTHR12357:SF3] SPLICING FACTOR YT521-B 169.71 0.6623 157 Mapoly0013s0183 [KOG2739] Leucine-rich acidic nuclear protein; [PF14580] Leucine-rich repeat; [PTHR11375] ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 171.18 0.6763 158 Mapoly0005s0151 [KOG2688] Transcription-associated recombination protein - Thp1p; [PTHR12732] UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING; [GO:0005515] protein binding; [PTHR12732:SF0] SUBFAMILY NOT NAMED; [PF01399] PCI domain 171.39 0.6046 159 Mapoly0010s0010 [GO:0005643] nuclear pore; [PF13874] Nucleoporin complex subunit 54; [PTHR13000] NUCLEOPORIN P54; [KOG3091] Nuclear pore complex, p54 component (sc Nup57) 172.32 0.6950 160 Mapoly0092s0039 [GO:0005524] ATP binding; [KOG0737] AAA+-type ATPase; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23074] AAA ATPASE 173.23 0.7039 161 Mapoly0065s0067 [PTHR13165] ARSENITE-RESISTANCE PROTEIN 2; [PF12066] Domain of unknown function (DUF3546); [PF04959] Arsenite-resistance protein 2; [KOG2295] C2H2 Zn-finger protein; [PTHR13165:SF0] SUBFAMILY NOT NAMED 173.90 0.6960 162 Mapoly0057s0099 [KOG4817] Unnamed protein 174.93 0.7173 163 Mapoly0118s0038 - 175.63 0.6889 164 Mapoly0031s0090 [KOG0379] Kelch repeat-containing proteins; [PF13418] Galactose oxidase, central domain; [PTHR23244] KELCH REPEAT DOMAIN; [PF13415] Galactose oxidase, central domain 176.75 0.7013 165 Mapoly0081s0051 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [2.7.11.1] Non-specific serine/threonine protein kinase.; [PF11640] Telomere-length maintenance and DNA damage repair; [PF00454] Phosphatidylinositol 3- and 4-kinase; [GO:0004674] protein serine/threonine kinase activity; [PF02260] FATC domain; [K04728] ataxia telangectasia mutated family protein [EC:2.7.11.1]; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED 178.16 0.6515 166 Mapoly0010s0094 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [PF00454] Phosphatidylinositol 3- and 4-kinase; [KOG0889] Histone acetyltransferase SAGA, TRRAP/TRA1 component, PI-3 kinase superfamily; [PTHR11139:SF1] ATM-RELATED; [K08874] transformation/transcription domain-associated protein; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED 178.39 0.6908 167 Mapoly0061s0044 [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2) 179.58 0.6943 168 Mapoly0009s0039 [GO:0030915] Smc5-Smc6 complex; [KOG2866] Uncharacterized conserved protein; [PTHR16140:SF0] SUBFAMILY NOT NAMED; [PTHR16140] UNCHARACTERIZED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08743] Nse4 C-terminal 180.45 0.6994 169 Mapoly0057s0025 [PTHR11142] PSEUDOURIDYLATE SYNTHASE; [GO:0003723] RNA binding; [K06173] tRNA pseudouridine synthase A [EC:5.4.99.12]; [GO:0001522] pseudouridine synthesis; [KOG2553] Pseudouridylate synthase; [GO:0009451] RNA modification; [PF01416] tRNA pseudouridine synthase; [GO:0009982] pseudouridine synthase activity; [5.4.99.12] tRNA pseudouridine(38-40) synthase. 180.86 0.6977 170 Mapoly0002s0004 [KOG1189] Global transcriptional regulator, cell division control protein; [PF00557] Metallopeptidase family M24; [PF08512] Histone chaperone Rttp106-like; [PTHR13980] CDC68 RELATED; [PF08644] FACT complex subunit (SPT16/CDC68) 181.61 0.6625 171 Mapoly0154s0005 [PTHR22852] LETHAL(2)DENTICLELESS PROTEIN (RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN); [KOG0265] U5 snRNP-specific protein-like factor and related proteins; [K11790] denticleless; [GO:0005515] protein binding; [PF00400] WD domain, G-beta repeat 181.87 0.6994 172 Mapoly0082s0057 [PTHR32282] FAMILY NOT NAMED; [PF00912] Transglycosylase; [PTHR32282:SF0] SUBFAMILY NOT NAMED; [PF00905] Penicillin binding protein transpeptidase domain; [GO:0008658] penicillin binding 184.16 0.6491 173 Mapoly0021s0007 [PTHR11851:SF85] AGR251CP; [3.4.24.56] Insulysin.; [KOG0959] N-arginine dibasic convertase NRD1 and related Zn2+-dependent endopeptidases, insulinase superfamily; [K01408] insulysin [EC:3.4.24.56]; [PTHR11851] METALLOPROTEASE; [PF05193] Peptidase M16 inactive domain; [PF00675] Insulinase (Peptidase family M16) 184.66 0.6519 174 Mapoly0009s0116 [PTHR12072] CWF19, CELL CYCLE CONTROL PROTEIN; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PTHR12072:SF4] SUBFAMILY NOT NAMED; [PF04677] Protein similar to CwfJ C-terminus 1; [GO:0046872] metal ion binding; [PF04676] Protein similar to CwfJ C-terminus 2 185.13 0.6935 175 Mapoly0075s0087 [PTHR31576] FAMILY NOT NAMED 186.47 0.7065 176 Mapoly0051s0060 [PTHR31399:SF0] SUBFAMILY NOT NAMED; [PF03121] Herpesviridae UL52/UL70 DNA primase; [GO:0006260] DNA replication; [GO:0003896] DNA primase activity; [PTHR31399] FAMILY NOT NAMED 186.98 0.6776 177 Mapoly0063s0006 [KOG2217] U4/U6.U5 snRNP associated protein; [K11984] U4/U6.U5 tri-snRNP-associated protein 1; [PTHR14152:SF5] SUBFAMILY NOT NAMED; [PTHR14152] SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES; [PF03343] SART-1 family 187.71 0.6897 178 Mapoly0003s0259 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PTHR24420:SF474] SUBFAMILY NOT NAMED; [PF00069] Protein kinase domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 188.04 0.6863 179 Mapoly0131s0010 [PTHR15921:SF3] SUBFAMILY NOT NAMED; [KOG2071] mRNA cleavage and polyadenylation factor I/II complex, subunit Pcf11; [PF04818] RNA polymerase II-binding domain.; [PTHR15921] PRE-MRNA CLEAVAGE COMPLEX II 188.04 0.7008 180 Mapoly0119s0057 [KOG2047] mRNA splicing factor; [PTHR11246] PRE-MRNA SPLICING FACTOR; [PTHR11246:SF5] XPA-BINDING PROTEIN 2 (HCNP PROTEIN); [K12867] pre-mRNA-splicing factor SYF1 192.27 0.6804 181 Mapoly0065s0078 [PTHR24115:SF171] SUBFAMILY NOT NAMED; [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [K10403] kinesin family member 22; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 192.82 0.6854 182 Mapoly0013s0109 [PF00514] Armadillo/beta-catenin-like repeat; [PF00651] BTB/POZ domain; [GO:0005515] protein binding; [KOG0166] Karyopherin (importin) alpha; [PTHR23315] BETA CATENIN-RELATED ARMADILLO REPEAT-CONTAINING 192.88 0.6733 183 Mapoly0030s0020 [KOG2545] Conserved membrane protein; [PTHR13489:SF0] SUBFAMILY NOT NAMED; [PF13615] Putative alanine racemase; [PF09739] Mini-chromosome maintenance replisome factor; [PTHR13489] UNCHARACTERIZED 193.12 0.6947 184 Mapoly0165s0024 [GO:0006338] chromatin remodeling; [GO:0043968] histone H2A acetylation; [PF00249] Myb-like DNA-binding domain; [K11324] DNA methyltransferase 1-associated protein 1; [GO:0043967] histone H4 acetylation; [KOG2656] DNA methyltransferase 1-associated protein-1; [GO:0003682] chromatin binding; [PTHR12855] FAMILY NOT NAMED; [GO:0035267] NuA4 histone acetyltransferase complex; [GO:0006281] DNA repair; [PTHR12855:SF10] SUBFAMILY NOT NAMED 194.84 0.6848 185 Mapoly0005s0196 [PTHR24011] FAMILY NOT NAMED; [PF04059] RNA recognition motif 2; [GO:0003676] nucleic acid binding; [KOG4660] Protein Mei2, essential for commitment to meiosis, and related proteins; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 198.91 0.6774 186 Mapoly0189s0011 [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain 200.24 0.6863 187 Mapoly0010s0152 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PTHR13561:SF5] DNA REPLICATION REGULATOR DPB11; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 200.45 0.6866 188 Mapoly0050s0134 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PF01751] Toprim domain; [PTHR10169] DNA TOPOISOMERASE/GYRASE; [GO:0006265] DNA topological change; [GO:0003918] DNA topoisomerase type II (ATP-hydrolyzing) activity; [PF00521] DNA gyrase/topoisomerase IV, subunit A; [KOG0355] DNA topoisomerase type II; [5.99.1.3] DNA topoisomerase (ATP-hydrolyzing).; [PF00204] DNA gyrase B; [K03164] DNA topoisomerase II [EC:5.99.1.3] 200.45 0.6812 189 Mapoly0069s0045 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0003910] DNA ligase (ATP) activity; [PF04679] ATP dependent DNA ligase C terminal region; [PTHR10459] DNA LIGASE; [PF01068] ATP dependent DNA ligase domain; [GO:0006281] DNA repair; [PF12706] Beta-lactamase superfamily domain; [PF04675] DNA ligase N terminus; [PF07522] DNA repair metallo-beta-lactamase; [GO:0006310] DNA recombination; [KOG0967] ATP-dependent DNA ligase I 200.98 0.6790 190 Mapoly0003s0063 [GO:0005524] ATP binding; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24361:SF129] MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE; [GO:0006468] protein phosphorylation; [PTHR24361] MITOGEN-ACTIVATED KINASE KINASE KINASE 201.15 0.6850 191 Mapoly0082s0056 [PTHR13211] UNCHARACTERIZED; [GO:0005515] protein binding; [KOG2919] Guanine nucleotide-binding protein; [PF00400] WD domain, G-beta repeat 201.65 0.6437 192 Mapoly0039s0055 [GO:0016876] ligase activity, forming aminoacyl-tRNA and related compounds; [PF00749] tRNA synthetases class I (E and Q), catalytic domain; [GO:0005524] ATP binding; [GO:0004819] glutamine-tRNA ligase activity; [GO:0005737] cytoplasm; [GO:0006425] glutaminyl-tRNA aminoacylation; [K01886] glutaminyl-tRNA synthetase [EC:6.1.1.18]; [PF04558] Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1; [GO:0000166] nucleotide binding; [GO:0043039] tRNA aminoacylation; [PF03950] tRNA synthetases class I (E and Q), anti-codon binding domain; [PF04557] Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2; [PTHR10119] GLUTAMYL/GLUTAMINYL-TRNA SYNTHETASE; [KOG1148] Glutaminyl-tRNA synthetase; [GO:0006418] tRNA aminoacylation for protein translation; [6.1.1.18] Glutamine--tRNA ligase.; [GO:0004812] aminoacyl-tRNA ligase activity 202.01 0.6684 193 Mapoly0008s0161 [GO:0051382] kinetochore assembly; [GO:0019237] centromeric DNA binding; [PTHR16684] CENTROMERE PROTEIN C; [GO:0000776] kinetochore 202.23 0.6496 194 Mapoly0099s0044 [PTHR13389] UNCHARACTERIZED 202.45 0.6875 195 Mapoly0004s0038 [PF10440] Ubiquitin-binding WIYLD domain; [KOG1082] Histone H3 (Lys9) methyltransferase SUV39H1/Clr4, required for transcriptional silencing; [PF05033] Pre-SET motif; [GO:0005515] protein binding; [PF00856] SET domain; [GO:0008270] zinc ion binding; [PTHR22884:SF23] SET DOMAIN PROTEIN; [GO:0018024] histone-lysine N-methyltransferase activity; [PTHR22884] SET DOMAIN PROTEINS; [GO:0005634] nucleus; [GO:0034968] histone lysine methylation 202.46 0.6266 196 Mapoly0151s0007 [GO:0008168] methyltransferase activity; [PTHR10920:SF13] RRNA METHYLTRANSFERASE 3; [PF11861] Domain of unknown function (DUF3381); [GO:0031167] rRNA methylation; [PTHR10920] RIBOSOMAL RNA METHYLTRANSFERASE; [GO:0032259] methylation; [PF01728] FtsJ-like methyltransferase; [KOG1098] Putative SAM-dependent rRNA methyltransferase SPB1; [GO:0005634] nucleus; [GO:0006364] rRNA processing; [PF07780] Spb1 C-terminal domain; [GO:0001510] RNA methylation; [GO:0008649] rRNA methyltransferase activity 203.48 0.6758 197 Mapoly0015s0126 [GO:0008641] small protein activating enzyme activity; [GO:0005524] ATP binding; [K10685] ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19]; [KOG2013] SMT3/SUMO-activating complex, catalytic component UBA2; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [PF14732] Ubiquitin/SUMO-activating enzyme ubiquitin-like domain 203.65 0.6817 198 Mapoly0014s0219 [K03165] DNA topoisomerase III [EC:5.99.1.2]; [GO:0003677] DNA binding; [GO:0003917] DNA topoisomerase type I activity; [PF01751] Toprim domain; [PTHR11390:SF20] DNA TOPOISOMERASE I,III; [GO:0006265] DNA topological change; [GO:0003916] DNA topoisomerase activity; [KOG1957] DNA topoisomerase III beta; [PTHR11390] PROKARYOTIC DNA TOPOISOMERASE; [5.99.1.2] DNA topoisomerase.; [PF01131] DNA topoisomerase 205.12 0.6066 199 Mapoly0070s0048 [GO:0005665] DNA-directed RNA polymerase II, core complex; [PF04998] RNA polymerase Rpb1, domain 5; [GO:0003677] DNA binding; [PF00623] RNA polymerase Rpb1, domain 2; [PTHR19376] DNA-DIRECTED RNA POLYMERASE; [PF05000] RNA polymerase Rpb1, domain 4; [PF04990] RNA polymerase Rpb1, domain 7; [PF05001] RNA polymerase Rpb1 C-terminal repeat; [PF04997] RNA polymerase Rpb1, domain 1; [GO:0006351] transcription, DNA-dependent; [KOG0260] RNA polymerase II, large subunit; [GO:0006366] transcription from RNA polymerase II promoter; [GO:0003899] DNA-directed RNA polymerase activity; [K03006] DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]; [PF04983] RNA polymerase Rpb1, domain 3; [2.7.7.6] DNA-directed RNA polymerase.; [PF04992] RNA polymerase Rpb1, domain 6; [PTHR19376:SF33] DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'' 205.88 0.6609 200 Mapoly0029s0012 [GO:0005524] ATP binding; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [KOG0329] ATP-dependent RNA helicase; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding 206.46 0.6926