| 1 |
Mapoly0070s0053
| [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF09382] RQC domain; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [K10901] bloom syndrome protein [EC:3.6.4.12]; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain | 1.41 | 0.8616 |
| 2 |
Mapoly0023s0143
| [GO:0005524] ATP binding; [PTHR23073] 26S PROTEASE REGULATORY SUBUNIT; [PTHR23073:SF18] SUBFAMILY NOT NAMED; [PF00004] ATPase family associated with various cellular activities (AAA) | 3.00 | 0.8544 |
| 3 |
Mapoly0016s0130
| [PF14817] HAUS augmin-like complex subunit 5; [GO:0051225] spindle assembly | 4.47 | 0.8479 |
| 4 |
Mapoly0102s0024
| [GO:0006355] regulation of transcription, DNA-dependent; [PF14443] DBC1; [KOG3227] Calcium-responsive transcription coactivator; [PTHR14304] P30 DBC PROTEIN | 4.69 | 0.8591 |
| 5 |
Mapoly0004s0202
| - | 6.32 | 0.8426 |
| 6 |
Mapoly0042s0049
| - | 6.32 | 0.8524 |
| 7 |
Mapoly0056s0030
| [KOG1040] Polyadenylation factor I complex, subunit, Yth1 (CPSF subunit); [PTHR12357] YTH (YT521-B HOMOLOGY) DOMAIN-CONTAINING; [PF04146] YT521-B-like domain; [PTHR12357:SF3] SPLICING FACTOR YT521-B | 7.21 | 0.7967 |
| 8 |
Mapoly0001s0406
| [GO:0000922] spindle pole; [KOG2000] Gamma-tubulin complex, DGRIP91/SPC98 component; [PF04130] Spc97 / Spc98 family; [GO:0005856] cytoskeleton; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [GO:0007020] microtubule nucleation; [PTHR19302:SF14] GAMMA-TUBULIN COMPLEX COMPONENT 3 (GCP-3) | 10.00 | 0.8190 |
| 9 |
Mapoly0052s0095
| [GO:0005643] nuclear pore; [PTHR31344:SF0] SUBFAMILY NOT NAMED; [K14310] nuclear pore complex protein Nup205; [PF11894] Protein of unknown function (DUF3414); [PTHR31344] FAMILY NOT NAMED; [KOG1835] Uncharacterized conserved protein | 10.00 | 0.8289 |
| 10 |
Mapoly0035s0137
| [GO:0005643] nuclear pore; [PTHR10350:SF6] NUCLEOPORIN 155; [PF03177] Non-repetitive/WGA-negative nucleoporin C-terminal; [K14312] nuclear pore complex protein Nup155; [KOG1900] Nuclear pore complex, Nup155 component (D Nup154, sc Nup157/Nup170); [GO:0006913] nucleocytoplasmic transport; [PF08801] Nup133 N terminal like; [GO:0017056] structural constituent of nuclear pore; [PTHR10350] NUCLEAR PORE COMPLEX PROTEIN NUP155 | 10.10 | 0.8442 |
| 11 |
Mapoly0034s0031
| [GO:0007094] mitotic spindle assembly checkpoint; [K06638] mitotic spindle assembly checkpoint protein MAD1; [KOG4593] Mitotic checkpoint protein MAD1; [PTHR23168] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 (MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1); [PF05557] Mitotic checkpoint protein; [PTHR23168:SF0] SUBFAMILY NOT NAMED | 10.25 | 0.8431 |
| 12 |
Mapoly0005s0051
| [GO:0003723] RNA binding; [GO:0000339] RNA cap binding; [GO:0045292] mRNA cis splicing, via spliceosome; [GO:0051028] mRNA transport; [PF02854] MIF4G domain; [GO:0005515] protein binding; [KOG1104] Nuclear cap-binding complex, subunit NCBP1/CBP80; [K12882] nuclear cap-binding protein subunit 1; [GO:0016070] RNA metabolic process; [PTHR12412] CAP BINDING PROTEIN; [GO:0005846] nuclear cap binding complex; [PF09090] MIF4G like; [PF09088] MIF4G like | 12.00 | 0.8413 |
| 13 |
Mapoly0043s0050
| [PTHR23019:SF0] SUBFAMILY NOT NAMED; [K14314] nuclear pore complex protein Nup210; [PF02368] Bacterial Ig-like domain (group 2); [PTHR23019] NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED; [KOG1833] Nuclear pore complex, gp210 component | 12.12 | 0.8258 |
| 14 |
Mapoly0026s0077
| [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [2.7.11.1] Non-specific serine/threonine protein kinase.; [PF08064] UME (NUC010) domain; [PF00454] Phosphatidylinositol 3- and 4-kinase; [K06640] ataxia telangiectasia and Rad3 related [EC:2.7.11.1]; [GO:0004674] protein serine/threonine kinase activity; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [KOG0890] Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination | 12.49 | 0.8184 |
| 15 |
Mapoly0105s0035
| [PTHR12341] 5'-3' EXORIBONUCLEASE; [PF03159] XRN 5'-3' exonuclease N-terminus; [K12619] 5'-3' exoribonuclease 2 [EC:3.1.13.-]; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [3.1.13.-] Exoribonucleases producing 5'-phosphomonoesters.; [GO:0003676] nucleic acid binding; [GO:0004527] exonuclease activity | 12.49 | 0.8360 |
| 16 |
Mapoly0010s0191
| [PF04055] Radical SAM superfamily; [PTHR13930] RSAFD1-RELATED; [PF00258] Flavodoxin; [PF08608] Wyosine base formation; [GO:0016491] oxidoreductase activity; [PTHR13930:SF0] SUBFAMILY NOT NAMED; [GO:0003824] catalytic activity; [GO:0051536] iron-sulfur cluster binding; [KOG1160] Fe-S oxidoreductase; [GO:0010181] FMN binding | 13.27 | 0.8241 |
| 17 |
Mapoly0082s0057
| [PTHR32282] FAMILY NOT NAMED; [PF00912] Transglycosylase; [PTHR32282:SF0] SUBFAMILY NOT NAMED; [PF00905] Penicillin binding protein transpeptidase domain; [GO:0008658] penicillin binding | 14.56 | 0.7705 |
| 18 |
Mapoly0001s0044
| [PTHR31110] FAMILY NOT NAMED | 15.49 | 0.8328 |
| 19 |
Mapoly0030s0101
| [GO:0042393] histone binding; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [K11647] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-]; [KOG0386] Chromatin remodeling complex SWI/SNF, component SWI2 and related ATPases (DNA/RNA helicase superfamily); [PTHR10799:SF209] GLOBAL TRANSCRIPTION ACTIVATOR SNF2L2 (ATP-DEPENDENT HELICASE SMARCA2); [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [PF14619] Snf2-ATP coupling, chromatin remodelling complex | 17.15 | 0.8329 |
| 20 |
Mapoly0010s0036
| [KOG2002] TPR-containing nuclear phosphoprotein that regulates K(+) uptake; [PF07719] Tetratricopeptide repeat; [PTHR14027:SF2] TPR REPEAT NUCLEAR PHOSPHOPROTEIN; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13174] Tetratricopeptide repeat; [PF13181] Tetratricopeptide repeat; [PF13424] Tetratricopeptide repeat; [PTHR14027] TPR REPEAT NUCLEAR PHOSPHOPROTEIN/CTR9; [PF00515] Tetratricopeptide repeat | 17.44 | 0.8295 |
| 21 |
Mapoly0081s0047
| [PF00773] RNB domain; [PF13638] PIN domain; [3.1.13.-] Exoribonucleases producing 5'-phosphomonoesters.; [K12585] exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]; [PTHR23355] RIBONUCLEASE; [KOG2102] Exosomal 3'-5' exoribonuclease complex, subunit Rrp44/Dis3 | 17.49 | 0.7984 |
| 22 |
Mapoly0138s0046
| [KOG1803] DNA helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PF13086] AAA domain; [PF13087] AAA domain | 17.66 | 0.8221 |
| 23 |
Mapoly0042s0082
| [GO:0005643] nuclear pore; [PF07926] TPR/MLP1/MLP2-like protein; [PTHR18898] NUCLEOPROTEIN TPR-RELATED; [K09291] nucleoprotein TPR; [KOG4674] Uncharacterized conserved coiled-coil protein; [GO:0006606] protein import into nucleus | 18.71 | 0.8401 |
| 24 |
Mapoly0004s0169
| [GO:0003677] DNA binding; [GO:0006338] chromatin remodeling; [GO:0005524] ATP binding; [PF09110] HAND; [K11654] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]; [GO:0043044] ATP-dependent chromatin remodeling; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [GO:0005634] nucleus; [PTHR10799:SF73] ISWI CHROMATIN-REMODELING COMPLEX ATPASE ISW1; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [KOG0385] Chromatin remodeling complex WSTF-ISWI, small subunit; [GO:0003676] nucleic acid binding; [GO:0031491] nucleosome binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [PF09111] SLIDE | 18.76 | 0.8324 |
| 25 |
Mapoly0167s0015
| [KOG1076] Translation initiation factor 3, subunit c (eIF-3c); [K03252] translation initiation factor eIF-3 subunit 8; [PF05470] Eukaryotic translation initiation factor 3 subunit 8 N-terminus; [PTHR13937:SF0] SUBFAMILY NOT NAMED; [GO:0003743] translation initiation factor activity; [GO:0005515] protein binding; [PTHR13937] EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 (EIF3S8)-RELATED; [GO:0031369] translation initiation factor binding; [PF01399] PCI domain; [GO:0006413] translational initiation; [GO:0005852] eukaryotic translation initiation factor 3 complex | 19.62 | 0.7815 |
| 26 |
Mapoly0108s0041
| [PTHR14978:SF0] SUBFAMILY NOT NAMED; [PTHR14978] BETA-CATENIN-LIKE PROTEIN 1 (NUCLEAR ASSOCIATED PROTEIN); [K12864] beta-catenin-like protein 1; [KOG2734] Uncharacterized conserved protein; [PF08216] Catenin-beta-like, Arm-motif containing nuclear | 20.00 | 0.7998 |
| 27 |
Mapoly0117s0005
| [K13109] IK cytokine; [PTHR12765] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [KOG2498] IK cytokine down-regulator of HLA class II; [PF07807] RED-like protein C-terminal region; [PTHR12765:SF5] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [GO:0005634] nucleus; [PF07808] RED-like protein N-terminal region | 21.63 | 0.8073 |
| 28 |
Mapoly0024s0107
| [PF07719] Tetratricopeptide repeat; [GO:0005515] protein binding; [PF13414] TPR repeat; [K03350] anaphase-promoting complex subunit 3; [KOG1126] DNA-binding cell division cycle control protein; [PF13181] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat; [PTHR12558] CELL DIVISION CYCLE 16,23,27; [PTHR12558:SF11] CELL DIVISION CYCLE 27; [PF12895] Anaphase-promoting complex, cyclosome, subunit 3 | 22.45 | 0.7940 |
| 29 |
Mapoly0131s0010
| [PTHR15921:SF3] SUBFAMILY NOT NAMED; [KOG2071] mRNA cleavage and polyadenylation factor I/II complex, subunit Pcf11; [PF04818] RNA polymerase II-binding domain.; [PTHR15921] PRE-MRNA CLEAVAGE COMPLEX II | 23.37 | 0.8359 |
| 30 |
Mapoly0036s0123
| [GO:0000922] spindle pole; [PTHR19302:SF13] GAMMA-TUBULIN COMPLEX COMPONENT 2 (GCP-2); [PF04130] Spc97 / Spc98 family; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [KOG2001] Gamma-tubulin complex, DGRIP84/SPC97 component | 24.04 | 0.8317 |
| 31 |
Mapoly0043s0081
| [GO:0005524] ATP binding; [PF02889] Sec63 Brl domain; [PTHR11752] HELICASE SKI2W; [3.6.4.13] RNA helicase.; [PF00270] DEAD/DEAH box helicase; [PTHR11752:SF7] U520; [PF00271] Helicase conserved C-terminal domain; [KOG0951] RNA helicase BRR2, DEAD-box superfamily; [GO:0003676] nucleic acid binding; [K12854] pre-mRNA-splicing helicase BRR2 [EC:3.6.4.13] | 24.33 | 0.8072 |
| 32 |
Mapoly0030s0009
| [PF00505] HMG (high mobility group) box; [KOG0526] Nucleosome-binding factor SPN, POB3 subunit; [PF03531] Structure-specific recognition protein (SSRP1); [PTHR13711:SF39] SUBFAMILY NOT NAMED; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [PF08512] Histone chaperone Rttp106-like; [K09272] structure-specific recognition protein 1 | 24.66 | 0.8124 |
| 33 |
Mapoly0002s0004
| [KOG1189] Global transcriptional regulator, cell division control protein; [PF00557] Metallopeptidase family M24; [PF08512] Histone chaperone Rttp106-like; [PTHR13980] CDC68 RELATED; [PF08644] FACT complex subunit (SPT16/CDC68) | 24.68 | 0.7790 |
| 34 |
Mapoly0033s0057
| [2.3.1.-] Transferring groups other than amino-acyl groups.; [PTHR11076:SF1] ESTABLISHMENT OF COHESION 1 (ECO1) HOMOLOG; [PF13880] ESCO1/2 acetyl-transferase; [PF13878] zinc-finger of acetyl-transferase ESCO; [KOG3014] Protein involved in establishing cohesion between sister chromatids during DNA replication; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [K11268] N-acetyltransferase [EC:2.3.1.-] | 25.04 | 0.8365 |
| 35 |
Mapoly0091s0014
| [PTHR12596:SF1] GB DEF: T27C4.14 PROTEIN; [PTHR12596] EXPORTIN 4,7-RELATED; [KOG4541] Nuclear transport receptor exportin 4 (importin beta superfamily) | 25.24 | 0.8009 |
| 36 |
Mapoly0042s0123
| [K12875] apoptotic chromatin condensation inducer in the nucleus; [GO:0003676] nucleic acid binding; [PTHR14127] APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; [PF02037] SAP domain | 25.38 | 0.8241 |
| 37 |
Mapoly0015s0126
| [GO:0008641] small protein activating enzyme activity; [GO:0005524] ATP binding; [K10685] ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19]; [KOG2013] SMT3/SUMO-activating complex, catalytic component UBA2; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [PF14732] Ubiquitin/SUMO-activating enzyme ubiquitin-like domain | 25.69 | 0.8110 |
| 38 |
Mapoly0002s0125
| [PTHR25040] FAMILY NOT NAMED; [PF11926] Domain of unknown function (DUF3444); [PTHR25040:SF79] SUBFAMILY NOT NAMED; [PF00226] DnaJ domain | 28.46 | 0.8299 |
| 39 |
Mapoly0125s0021
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR23273:SF0] SUBFAMILY NOT NAMED; [GO:0008270] zinc ion binding; [PF04057] Replication factor-A protein 1, N-terminal domain; [PF00098] Zinc knuckle; [GO:0005634] nucleus; [PF08646] Replication factor-A C terminal domain; [GO:0003676] nucleic acid binding; [K07466] replication factor A1; [PTHR23273] REPLICATION FACTOR A 1, RFA1; [PF01336] OB-fold nucleic acid binding domain | 29.58 | 0.7577 |
| 40 |
Mapoly0031s0090
| [KOG0379] Kelch repeat-containing proteins; [PF13418] Galactose oxidase, central domain; [PTHR23244] KELCH REPEAT DOMAIN; [PF13415] Galactose oxidase, central domain | 32.03 | 0.8179 |
| 41 |
Mapoly0098s0023
| [PTHR19378] GOLGIN- RELATED; [PF14932] HAUS augmin-like complex subunit 3; [GO:0051225] spindle assembly; [GO:0070652] HAUS complex; [PTHR19378:SF0] SUBFAMILY NOT NAMED | 33.23 | 0.7883 |
| 42 |
Mapoly0034s0011
| [PF09133] SANTA (SANT Associated) | 33.47 | 0.8104 |
| 43 |
Mapoly0074s0043
| [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [GO:0003729] mRNA binding | 33.63 | 0.8058 |
| 44 |
Mapoly0013s0059
| [GO:0005515] protein binding; [PF02213] GYF domain; [PTHR14445] GRB10 INTERACTING GYF PROTEIN | 34.00 | 0.8108 |
| 45 |
Mapoly0008s0250
| [PTHR24007] BRCA1-ASSOCIATED PROTEIN; [PF00917] MATH domain; [GO:0005515] protein binding; [GO:0006281] DNA repair; [PF14631] Fanconi anaemia protein FancD2 nuclease; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains | 34.06 | 0.7931 |
| 46 |
Mapoly0042s0086
| [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K08737] DNA mismatch repair protein MSH6; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PTHR11361:SF31] MUTS HOMOLOG 6, MSH6; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV | 35.24 | 0.7959 |
| 47 |
Mapoly0001s0472
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED | 35.50 | 0.8157 |
| 48 |
Mapoly0047s0024
| [KOG1142] Transcription initiation factor TFIID, subunit TAF12 (also component of histone acetyltransferase SAGA); [GO:0006352] DNA-dependent transcription, initiation; [PF03847] Transcription initiation factor TFIID subunit A; [PTHR12264] FAMILY NOT NAMED; [K03126] transcription initiation factor TFIID subunit 12; [GO:0005669] transcription factor TFIID complex | 37.75 | 0.7824 |
| 49 |
Mapoly0130s0046
| [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF14493] Helix-turn-helix domain; [PF09382] RQC domain; [K10900] werner syndrome ATP-dependent helicase [EC:3.6.4.12]; [KOG0353] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain | 38.37 | 0.8037 |
| 50 |
Mapoly0009s0015
| [PF00078] Reverse transcriptase (RNA-dependent DNA polymerase); [PTHR12066] TELOMERASE REVERSE TRANSCRIPTASE; [GO:0003964] RNA-directed DNA polymerase activity; [K11126] telomerase reverse transcriptase [EC:2.7.7.49]; [PTHR12066:SF0] SUBFAMILY NOT NAMED; [2.7.7.49] RNA-directed DNA polymerase.; [PF12009] Telomerase ribonucleoprotein complex - RNA binding domain; [KOG1005] Telomerase catalytic subunit/reverse transcriptase TERT | 38.79 | 0.8048 |
