Guide Gene
- Gene ID
- Mapoly0005s0161
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [GO:0003677] DNA binding; [PTHR13451:SF0] SUBFAMILY NOT NAMED; [3.1.22.-] Endodeoxyribonucleases producing other than 5'-phosphomonoesters.; [K08991] crossover junction endonuclease MUS81 [EC:3.1.22.-]; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PF02732] ERCC4 domain
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0005s0161 [GO:0003677] DNA binding; [PTHR13451:SF0] SUBFAMILY NOT NAMED; [3.1.22.-] Endodeoxyribonucleases producing other than 5'-phosphomonoesters.; [K08991] crossover junction endonuclease MUS81 [EC:3.1.22.-]; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PF02732] ERCC4 domain 0.00 1.0000 1 Mapoly0138s0046 [KOG1803] DNA helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PF13086] AAA domain; [PF13087] AAA domain 6.78 0.8055 2 Mapoly0033s0057 [2.3.1.-] Transferring groups other than amino-acyl groups.; [PTHR11076:SF1] ESTABLISHMENT OF COHESION 1 (ECO1) HOMOLOG; [PF13880] ESCO1/2 acetyl-transferase; [PF13878] zinc-finger of acetyl-transferase ESCO; [KOG3014] Protein involved in establishing cohesion between sister chromatids during DNA replication; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [K11268] N-acetyltransferase [EC:2.3.1.-] 9.06 0.8177 3 Mapoly0158s0032 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [K10728] topoisomerase (DNA) II binding protein 1; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 12.41 0.7702 4 Mapoly0072s0079 [PF11717] RNA binding activity-knot of a chromodomain; [K11339] mortality factor 4-like protein 1; [GO:0005634] nucleus; [PTHR10880] MORTALITY FACTOR 4-LIKE PROTEIN; [PF05712] MRG 12.61 0.7924 5 Mapoly0032s0034 - 13.42 0.7873 6 Mapoly0060s0110 [PF15072] Domain of unknown function (DUF4539); [PTHR14523] FAMILY NOT NAMED; [PTHR14523:SF1] SUBFAMILY NOT NAMED 18.84 0.7845 7 Mapoly0116s0041 [PF13297] Telomere stability C-terminal; [PTHR12786:SF2] SPLICING FACTOR 3A; [PF12108] Splicing factor SF3a60 binding domain; [KOG2636] Splicing factor 3a, subunit 3; [PTHR12786] SPLICING FACTOR SF3A-RELATED; [K12827] splicing factor 3A subunit 3; [PF11931] Domain of unknown function (DUF3449) 22.61 0.7757 8 Mapoly0031s0090 [KOG0379] Kelch repeat-containing proteins; [PF13418] Galactose oxidase, central domain; [PTHR23244] KELCH REPEAT DOMAIN; [PF13415] Galactose oxidase, central domain 22.72 0.7799 9 Mapoly0010s0010 [GO:0005643] nuclear pore; [PF13874] Nucleoporin complex subunit 54; [PTHR13000] NUCLEOPORIN P54; [KOG3091] Nuclear pore complex, p54 component (sc Nup57) 26.25 0.7643 10 Mapoly0023s0072 [3.1.27.-] Endoribonucleases producing other than 5'-phosphomonoesters.; [K13148] integrator complex subunit 11 [EC:3.1.27.-]; [PF07521] RNA-metabolising metallo-beta-lactamase; [PTHR11203] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF00753] Metallo-beta-lactamase superfamily; [PTHR11203:SF11] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF10996] Beta-Casp domain; [KOG1136] Predicted cleavage and polyadenylation specificity factor (CPSF subunit) 26.98 0.7475 11 Mapoly0005s0051 [GO:0003723] RNA binding; [GO:0000339] RNA cap binding; [GO:0045292] mRNA cis splicing, via spliceosome; [GO:0051028] mRNA transport; [PF02854] MIF4G domain; [GO:0005515] protein binding; [KOG1104] Nuclear cap-binding complex, subunit NCBP1/CBP80; [K12882] nuclear cap-binding protein subunit 1; [GO:0016070] RNA metabolic process; [PTHR12412] CAP BINDING PROTEIN; [GO:0005846] nuclear cap binding complex; [PF09090] MIF4G like; [PF09088] MIF4G like 27.86 0.7752 12 Mapoly0051s0060 [PTHR31399:SF0] SUBFAMILY NOT NAMED; [PF03121] Herpesviridae UL52/UL70 DNA primase; [GO:0006260] DNA replication; [GO:0003896] DNA primase activity; [PTHR31399] FAMILY NOT NAMED 28.84 0.7585 13 Mapoly0045s0061 [KOG1081] Transcription factor NSD1 and related SET domain proteins; [GO:0005515] protein binding; [PF00856] SET domain; [PTHR22884] SET DOMAIN PROTEINS 29.80 0.7672 14 Mapoly0030s0009 [PF00505] HMG (high mobility group) box; [KOG0526] Nucleosome-binding factor SPN, POB3 subunit; [PF03531] Structure-specific recognition protein (SSRP1); [PTHR13711:SF39] SUBFAMILY NOT NAMED; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [PF08512] Histone chaperone Rttp106-like; [K09272] structure-specific recognition protein 1 30.40 0.7636 15 Mapoly0041s0060 [GO:0003677] DNA binding; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PTHR13451:SF3] gb def: Hypothetical protein F6I18.220 (Hypothetical protein AT4g30870); [PF02732] ERCC4 domain 31.32 0.7720 16 Mapoly0042s0049 - 31.94 0.7708 17 Mapoly0069s0072 [GO:0005524] ATP binding; [GO:0008026] ATP-dependent helicase activity; [3.6.4.13] RNA helicase.; [PF13307] Helicase C-terminal domain; [PTHR11472] DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; [GO:0006139] nucleobase-containing compound metabolic process; [GO:0003676] nucleic acid binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [K11273] chromosome transmission fidelity protein 1 [EC:3.6.4.13] 35.20 0.7552 18 Mapoly0113s0005 - 38.65 0.7564 19 Mapoly0004s0250 [GO:0005643] nuclear pore; [PF07817] GLE1-like protein; [GO:0016973] poly(A)+ mRNA export from nucleus; [KOG2412] Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor; [PTHR12960:SF0] SUBFAMILY NOT NAMED; [PTHR12960] GLE-1-RELATED 44.45 0.7509 20 Mapoly0133s0013 [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10615] HISTONE ACETYLTRANSFERASE; [PF00856] SET domain 45.17 0.7591 21 Mapoly0070s0053 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF09382] RQC domain; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [K10901] bloom syndrome protein [EC:3.6.4.12]; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 45.54 0.7573 22 Mapoly0001s0525 [K14408] cleavage stimulation factor subunit 3; [GO:0006397] mRNA processing; [GO:0005634] nucleus; [KOG1914] mRNA cleavage and polyadenylation factor I complex, subunit RNA14; [PTHR19980] RNA CLEAVAGE STIMULATION FACTOR; [PF05843] Suppressor of forked protein (Suf) 45.92 0.7560 23 Mapoly0221s0003 - 46.90 0.7554 24 Mapoly0001s0170 - 50.55 0.7363 25 Mapoly0004s0202 - 52.99 0.7512 26 Mapoly0013s0006 [GO:0008270] zinc ion binding; [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PTHR23336] ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3.; [PF07496] CW-type Zinc Finger 53.72 0.7292 27 Mapoly0034s0031 [GO:0007094] mitotic spindle assembly checkpoint; [K06638] mitotic spindle assembly checkpoint protein MAD1; [KOG4593] Mitotic checkpoint protein MAD1; [PTHR23168] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 (MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1); [PF05557] Mitotic checkpoint protein; [PTHR23168:SF0] SUBFAMILY NOT NAMED 56.54 0.7528 28 Mapoly0047s0105 [KOG4308] LRR-containing protein; [PTHR10098] RAPSYN-RELATED; [PF13516] Leucine Rich repeat; [PF13414] TPR repeat 60.93 0.7448 29 Mapoly0105s0060 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [K12898] heterogeneous nuclear ribonucleoprotein F/H; [KOG4211] Splicing factor hnRNP-F and related RNA-binding proteins; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED 64.03 0.7512 30 Mapoly0165s0024 [GO:0006338] chromatin remodeling; [GO:0043968] histone H2A acetylation; [PF00249] Myb-like DNA-binding domain; [K11324] DNA methyltransferase 1-associated protein 1; [GO:0043967] histone H4 acetylation; [KOG2656] DNA methyltransferase 1-associated protein-1; [GO:0003682] chromatin binding; [PTHR12855] FAMILY NOT NAMED; [GO:0035267] NuA4 histone acetyltransferase complex; [GO:0006281] DNA repair; [PTHR12855:SF10] SUBFAMILY NOT NAMED 64.36 0.7303 31 Mapoly0001s0472 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED 65.52 0.7480 32 Mapoly0011s0202 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain 66.17 0.7548 33 Mapoly0019s0059 [PTHR31398:SF0] SUBFAMILY NOT NAMED; [PTHR31398] FAMILY NOT NAMED; [PF03962] Mnd1 family; [KOG3433] Protein involved in meiotic recombination/predicted coiled-coil protein 66.86 0.7413 34 Mapoly0117s0005 [K13109] IK cytokine; [PTHR12765] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [KOG2498] IK cytokine down-regulator of HLA class II; [PF07807] RED-like protein C-terminal region; [PTHR12765:SF5] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [GO:0005634] nucleus; [PF07808] RED-like protein N-terminal region 67.19 0.7250 35 Mapoly0024s0131 - 69.65 0.7384 36 Mapoly0019s0119 - 71.30 0.7410 37 Mapoly0011s0047 [PTHR12972] DOWNSTREAM NEIGHBOR OF SON 73.79 0.7162 38 Mapoly0122s0062 [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 77.77 0.7392 39 Mapoly0097s0064 [PTHR13710:SF1] ROTHMUND-THOMSON SYNDROME DNA HELICASE RECQ4; [GO:0005524] ATP binding; [PF11719] DNA replication and checkpoint protein; [K10730] ATP-dependent DNA helicase Q4 [EC:3.6.4.12]; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [GO:0003676] nucleic acid binding; [PF02037] SAP domain 78.23 0.7362 40 Mapoly0078s0012 [GO:0006396] RNA processing; [PTHR11061] RNA M5U METHYLTRANSFERASE FAMILY; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0008173] RNA methyltransferase activity; [PF05958] tRNA (Uracil-5-)-methyltransferase; [GO:0046872] metal ion binding; [KOG2187] tRNA uracil-5-methyltransferase and related tRNA-modifying enzymes 80.60 0.7132 41 Mapoly0061s0085 [PF14868] Domain of unknown function (DUF4487) 82.22 0.7274 42 Mapoly0023s0090 [PF00249] Myb-like DNA-binding domain; [GO:0003682] chromatin binding; [PTHR22929] RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR B; [PTHR22929:SF0] SUBFAMILY NOT NAMED 83.39 0.7133 43 Mapoly0029s0028 [PF00249] Myb-like DNA-binding domain; [GO:0005515] protein binding; [PF00569] Zinc finger, ZZ type; [GO:0003682] chromatin binding; [GO:0008270] zinc ion binding; [PF04433] SWIRM domain; [PTHR12374] TRANSCRIPTIONAL ADAPTOR 2 (ADA2)-RELATED; [KOG0457] Histone acetyltransferase complex SAGA/ADA, subunit ADA2; [K11314] transcriptional adapter 2-alpha 84.85 0.7085 44 Mapoly0005s0044 [K14321] nucleoporin-like protein 2; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 85.64 0.6605 45 Mapoly0226s0007 [PF00817] impB/mucB/samB family; [2.7.7.7] DNA-directed DNA polymerase.; [GO:0006281] DNA repair; [PF11799] impB/mucB/samB family C-terminal domain; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [PTHR11076:SF11] DNA POLYMERASE ETA; [GO:0003887] DNA-directed DNA polymerase activity; [GO:0003684] damaged DNA binding; [K03509] DNA polymerase eta subunit [EC:2.7.7.7] 85.70 0.6669 46 Mapoly0068s0001 [K10736] minichromosome maintenance protein 10; [GO:0006260] DNA replication; [PTHR13454] FAMILY NOT NAMED; [PF09329] Primase zinc finger; [GO:0005634] nucleus 85.91 0.7224 47 Mapoly0097s0045 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11752] HELICASE SKI2W; [2.7.7.7] DNA-directed DNA polymerase.; [K02349] DNA polymerase theta subunit [EC:2.7.7.7]; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF00476] DNA polymerase family A; [GO:0003676] nucleic acid binding; [GO:0003887] DNA-directed DNA polymerase activity; [KOG0950] DNA polymerase theta/eta, DEAD-box superfamily 86.36 0.7052 48 Mapoly0005s0174 [GO:0005524] ATP binding; [KOG0933] Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E); [GO:0007076] mitotic chromosome condensation; [GO:0005515] protein binding; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0000796] condensin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PTHR18937:SF9] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC2; [K06674] structural maintenance of chromosome 2; [PF06470] SMC proteins Flexible Hinge Domain 86.49 0.7369 49 Mapoly0098s0012 [PTHR23147] SERINE/ARGININE RICH SPLICING FACTOR; [KOG0126] Predicted RNA-binding protein (RRM superfamily); [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 87.64 0.6873 50 Mapoly0063s0071 [GO:0005515] protein binding; [K12176] COP9 signalosome complex subunit 2; [KOG1464] COP9 signalosome, subunit CSN2; [PF01399] PCI domain; [PTHR10678] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 87.98 0.6915 51 Mapoly0034s0011 [PF09133] SANTA (SANT Associated) 89.41 0.7271 52 Mapoly0113s0048 [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [KOG1408] WD40 repeat protein; [PF00400] WD domain, G-beta repeat 90.02 0.7307 53 Mapoly0108s0041 [PTHR14978:SF0] SUBFAMILY NOT NAMED; [PTHR14978] BETA-CATENIN-LIKE PROTEIN 1 (NUCLEAR ASSOCIATED PROTEIN); [K12864] beta-catenin-like protein 1; [KOG2734] Uncharacterized conserved protein; [PF08216] Catenin-beta-like, Arm-motif containing nuclear 90.23 0.7042 54 Mapoly0019s0115 [PTHR23002] ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN; [PF14392] Zinc knuckle; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding 90.47 0.6921 55 Mapoly0045s0049 - 91.65 0.6836 56 Mapoly0042s0123 [K12875] apoptotic chromatin condensation inducer in the nucleus; [GO:0003676] nucleic acid binding; [PTHR14127] APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; [PF02037] SAP domain 93.24 0.7266 57 Mapoly0002s0133 [GO:0007076] mitotic chromosome condensation; [PTHR13108] FAMILY NOT NAMED; [PF05786] Condensin complex subunit 2; [KOG2328] Chromosome condensation complex Condensin, subunit H; [GO:0000796] condensin complex; [K06676] condensin complex subunit 2 93.34 0.7227 58 Mapoly0010s0026 [GO:0006357] regulation of transcription from RNA polymerase II promoter; [PTHR13114] TRANSCRIPTIONAL CO-ACTIVATOR CRSP77-RELATED; [PF10156] Subunit 17 of Mediator complex; [GO:0001104] RNA polymerase II transcription cofactor activity; [GO:0016592] mediator complex 93.51 0.6614 59 Mapoly0092s0013 [GO:0003723] RNA binding; [PTHR13326] TRNA PSEUDOURIDINE SYNTHASE D; [GO:0001522] pseudouridine synthesis; [GO:0009451] RNA modification; [PF01142] tRNA pseudouridine synthase D (TruD); [GO:0009982] pseudouridine synthase activity; [KOG2339] Uncharacterized conserved protein 94.39 0.6971 60 Mapoly0030s0101 [GO:0042393] histone binding; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [K11647] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-]; [KOG0386] Chromatin remodeling complex SWI/SNF, component SWI2 and related ATPases (DNA/RNA helicase superfamily); [PTHR10799:SF209] GLOBAL TRANSCRIPTION ACTIVATOR SNF2L2 (ATP-DEPENDENT HELICASE SMARCA2); [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [PF14619] Snf2-ATP coupling, chromatin remodelling complex 94.74 0.7217 61 Mapoly0107s0034 [3.5.1.98] Histone deacetylase.; [KOG1342] Histone deacetylase complex, catalytic component RPD3; [K06067] histone deacetylase 1/2 [EC:3.5.1.98]; [PF00850] Histone deacetylase domain; [PTHR10625] HISTONE DEACETYLASE 97.57 0.7040 62 Mapoly0047s0092 [PF00899] ThiF family; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [KOG2018] Predicted dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis; [GO:0003824] catalytic activity 97.87 0.6853 63 Mapoly0099s0044 [PTHR13389] UNCHARACTERIZED 99.50 0.7202 64 Mapoly0042s0023 [GO:0005524] ATP binding; [2.7.12.1] Dual-specificity kinase.; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [K08866] serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]; [PTHR22974] MIXED LINEAGE PROTEIN KINASE 100.22 0.7212 65 Mapoly0069s0083 [K11662] actin-related protein 6; [PF00022] Actin; [PTHR11937:SF21] ACTIN-LIKE PROTEIN; [PTHR11937] ACTIN; [KOG0680] Actin-related protein - Arp6p 100.40 0.6592 66 Mapoly0024s0112 [GO:0005643] nuclear pore; [KOG1964] Nuclear pore complex, rNup107 component (sc Nup84); [PTHR13003] NUP107-RELATED; [GO:0006810] transport; [PF04121] Nuclear pore protein 84 / 107; [K14301] nuclear pore complex protein Nup107 102.62 0.7170 67 Mapoly0167s0009 [GO:0005524] ATP binding; [KOG0348] ATP-dependent RNA helicase; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR24031:SF89] ATP-INDEPENDENT RNA HELICASE; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF13959] Domain of unknown function (DUF4217) 103.44 0.6862 68 Mapoly0015s0126 [GO:0008641] small protein activating enzyme activity; [GO:0005524] ATP binding; [K10685] ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19]; [KOG2013] SMT3/SUMO-activating complex, catalytic component UBA2; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [PF14732] Ubiquitin/SUMO-activating enzyme ubiquitin-like domain 104.40 0.7062 69 Mapoly0032s0119 [GO:0007076] mitotic chromosome condensation; [K06678] condensin complex subunit 3; [GO:0000796] condensin complex; [PTHR14418] CONDENSIN COMPLEX SUBUNIT 3-RELATED; [PF12719] Nuclear condensing complex subunits, C-term domain 105.24 0.7182 70 Mapoly0082s0082 - 105.77 0.6867 71 Mapoly0180s0011 - 107.54 0.6288 72 Mapoly0043s0064 [PF10979] Protein of unknown function (DUF2786) 108.23 0.7177 73 Mapoly0013s0140 [K13107] RNA-binding motif protein, X-linked 2; [KOG0126] Predicted RNA-binding protein (RRM superfamily); [PTHR23139] RNA-BINDING PROTEIN; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 108.67 0.6345 74 Mapoly0044s0021 [KOG0275] Conserved WD40 repeat-containing protein; [PTHR22848] WD40 REPEAT PROTEIN; [GO:0005515] protein binding; [K13111] WD40 repeat-containing protein SMU1; [PF00400] WD domain, G-beta repeat 109.23 0.6991 75 Mapoly0003s0057 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination 110.86 0.7192 76 Mapoly0026s0077 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [2.7.11.1] Non-specific serine/threonine protein kinase.; [PF08064] UME (NUC010) domain; [PF00454] Phosphatidylinositol 3- and 4-kinase; [K06640] ataxia telangiectasia and Rad3 related [EC:2.7.11.1]; [GO:0004674] protein serine/threonine kinase activity; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [KOG0890] Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination 111.00 0.6990 77 Mapoly0051s0023 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III 111.24 0.7220 78 Mapoly0209s0008 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF67] DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 111.39 0.7219 79 Mapoly0079s0030 [KOG0543] FKBP-type peptidyl-prolyl cis-trans isomerase; [PTHR10516] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF13414] TPR repeat; [GO:0006457] protein folding; [PF00254] FKBP-type peptidyl-prolyl cis-trans isomerase 112.27 0.6238 80 Mapoly0092s0032 [PTHR22597] POLYCOMB GROUP PROTEIN; [PTHR22597:SF0] SUBFAMILY NOT NAMED; [PF09733] VEFS-Box of polycomb protein 113.01 0.7067 81 Mapoly0004s0300 [GO:0005524] ATP binding; [PTHR11909:SF7] CELL DIVISION CONTROL PROTEIN 7; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K02214] cell division control protein 7 [EC:2.7.11.1]; [KOG1167] Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination; [GO:0006468] protein phosphorylation; [PTHR11909] CASEIN KINASE-RELATED 113.49 0.7158 82 Mapoly0079s0005 [GO:0008080] N-acetyltransferase activity; [GO:0016568] chromatin modification; [PF00583] Acetyltransferase (GNAT) family; [GO:0005634] nucleus; [GO:0004402] histone acetyltransferase activity; [GO:0016573] histone acetylation; [KOG2696] Histone acetyltransferase type b catalytic subunit; [GO:0006348] chromatin silencing at telomere; [2.3.1.48] Histone acetyltransferase.; [PTHR12046] HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT; [K11303] histone acetyltransferase 1 [EC:2.3.1.48]; [PF10394] Histone acetyl transferase HAT1 N-terminus 114.82 0.7059 83 Mapoly0080s0056 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K10738] minichromosome maintenance protein 9; [PTHR11630:SF48] DNA REPLICATION LICENSING FACTOR MCM1; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [KOG0477] DNA replication licensing factor, MCM2 component 115.41 0.6656 84 Mapoly0118s0005 [GO:0008233] peptidase activity; [3.4.22.49] Separase.; [K02365] separase [EC:3.4.22.49]; [GO:0005634] nucleus; [PF03568] Peptidase family C50; [GO:0006508] proteolysis; [PTHR12792] EXTRA SPINDLE POLES 1-RELATED 120.58 0.7048 85 Mapoly0130s0046 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF14493] Helix-turn-helix domain; [PF09382] RQC domain; [K10900] werner syndrome ATP-dependent helicase [EC:3.6.4.12]; [KOG0353] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 120.94 0.7036 86 Mapoly0108s0031 [GO:0005524] ATP binding; [K04499] RuvB-like protein 1 (pontin 52); [KOG1942] DNA helicase, TBP-interacting protein; [PF06068] TIP49 C-terminus; [GO:0043141] ATP-dependent 5'-3' DNA helicase activity; [GO:0003678] DNA helicase activity; [PTHR11093] RUVB-RELATED REPTIN AND PONTIN 121.33 0.6975 87 Mapoly0014s0207 [PTHR14212] U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED; [GO:0046540] U4/U6 x U5 tri-snRNP complex; [K12843] U4/U6 small nuclear ribonucleoprotein PRP3; [GO:0000398] mRNA splicing, via spliceosome; [KOG2769] Putative u4/u6 small nuclear ribonucleoprotein; [PF06544] Protein of unknown function (DUF1115); [PF08572] pre-mRNA processing factor 3 (PRP3) 121.69 0.7118 88 Mapoly0103s0054 [PTHR24067:SF59] UBIQUITIN-CONJUGATING ENZYME E2 T; [K13960] ubiquitin-conjugating enzyme E2 T [EC:6.3.2.19]; [PTHR24067] UBIQUITIN-CONJUGATING ENZYME E2; [GO:0016881] acid-amino acid ligase activity; [6.3.2.19] Ubiquitin--protein ligase.; [KOG0417] Ubiquitin-protein ligase; [PF00179] Ubiquitin-conjugating enzyme 121.74 0.6721 89 Mapoly0001s0263 [PF08766] DEK C terminal domain; [GO:0005515] protein binding; [KOG1946] RNA polymerase I transcription factor UAF; [PF02201] SWIB/MDM2 domain; [PTHR13844] BRG-1 ASSOCIATED FACTOR 60 (BAF60) 123.16 0.6101 90 Mapoly0019s0032 - 124.13 0.7010 91 Mapoly0080s0001 [GO:0005515] protein binding; [PTHR15271] CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; [KOG1009] Chromatin assembly complex 1 subunit B/CAC2 (contains WD40 repeats); [K10751] chromatin assembly factor 1 subunit B; [PF00400] WD domain, G-beta repeat 124.79 0.7046 92 Mapoly0143s0027 [PTHR22851] U3 SMALL NUCLEOLAR RNA (U3 SNORNA) ASSOCIATED PROTEIN; [PTHR22851:SF0] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [KOG0268] Sof1-like rRNA processing protein (contains WD40 repeats); [K11806] WD repeat and SOF domain-containing protein 1; [PF04158] Sof1-like domain; [PF00400] WD domain, G-beta repeat 126.57 0.6957 93 Mapoly0009s0116 [PTHR12072] CWF19, CELL CYCLE CONTROL PROTEIN; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PTHR12072:SF4] SUBFAMILY NOT NAMED; [PF04677] Protein similar to CwfJ C-terminus 1; [GO:0046872] metal ion binding; [PF04676] Protein similar to CwfJ C-terminus 2 127.07 0.6985 94 Mapoly0008s0081 [PTHR21286] NUCLEAR PORE COMPLEX PROTEIN NUP160; [K14303] nuclear pore complex protein Nup160; [KOG4521] Nuclear pore complex, Nup160 component; [PF11715] Nucleoporin Nup120/160 129.75 0.7055 95 Mapoly0001s0362 - 130.00 0.6718 96 Mapoly0019s0003 [PTHR11079] CYTOSINE DEAMINASE; [GO:0016787] hydrolase activity; [PF00383] Cytidine and deoxycytidylate deaminase zinc-binding region; [GO:0008270] zinc ion binding; [PTHR11079:SF3] CYTIDINE AND DEOXYCYTIDYLATE DEAMINASE ZINC-BINDING REGION 131.15 0.6427 97 Mapoly0001s0481 [KOG1190] Polypyrimidine tract-binding protein; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [PTHR11546] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 131.53 0.6979 98 Mapoly0016s0006 [PTHR19923] WD40 REPEAT PROTEINPRL1/PRL2-RELATED; [PTHR19923:SF0] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [K12862] pleiotropic regulator 1; [KOG0285] Pleiotropic regulator 1; [PF00400] WD domain, G-beta repeat 131.77 0.6872 99 Mapoly0043s0112 [PTHR21780] UNCHARACTERIZED; [KOG4670] Uncharacterized conserved membrane protein; [PTHR21780:SF0] SUBFAMILY NOT NAMED; [PF09786] Cytochrome B561, N terminal 131.87 0.7005 100 Mapoly0023s0143 [GO:0005524] ATP binding; [PTHR23073] 26S PROTEASE REGULATORY SUBUNIT; [PTHR23073:SF18] SUBFAMILY NOT NAMED; [PF00004] ATPase family associated with various cellular activities (AAA) 134.01 0.7007 101 Mapoly0033s0098 [PTHR16047] RFWD3 PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PTHR16047:SF7] RFWD3 PROTEIN-RELATED; [KOG1645] RING-finger-containing E3 ubiquitin ligase 134.07 0.6924 102 Mapoly0101s0048 [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat 135.55 0.7000 103 Mapoly0081s0073 - 135.99 0.6907 104 Mapoly0023s0117 [PTHR10139] DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11A; [PF04152] Mre11 DNA-binding presumed domain; [KOG2310] DNA repair exonuclease MRE11; [GO:0006259] DNA metabolic process; [PF00149] Calcineurin-like phosphoesterase; [GO:0006302] double-strand break repair; [GO:0016787] hydrolase activity; [GO:0030145] manganese ion binding; [GO:0005634] nucleus; [GO:0004527] exonuclease activity; [K10865] double-strand break repair protein MRE11; [GO:0004519] endonuclease activity 136.46 0.6879 105 Mapoly0066s0041 [GO:0030915] Smc5-Smc6 complex; [PTHR21330] UNCHARACTERIZED; [GO:0019789] SUMO ligase activity; [PF11789] Zinc-finger of the MIZ type in Nse subunit; [GO:0000724] double-strand break repair via homologous recombination 136.82 0.6748 106 Mapoly0074s0043 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [GO:0003729] mRNA binding 136.86 0.6954 107 Mapoly0009s0225 [PTHR22942] RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER; [KOG1564] DNA repair protein RHP57; [PTHR22942:SF24] SUBFAMILY NOT NAMED; [K10880] DNA-repair protein XRCC3; [PF08423] Rad51 137.48 0.6734 108 Mapoly0137s0008 [PF06278] Protein of unknown function (DUF1032); [PTHR14324] FAMILY NOT NAMED; [PTHR14324:SF3] SUBFAMILY NOT NAMED; [K11490] condensin-2 complex subunit H2; [KOG2359] Uncharacterized conserved protein 138.24 0.6871 109 Mapoly0060s0046 [GO:0006396] RNA processing; [PTHR11246] PRE-MRNA SPLICING FACTOR; [KOG1915] Cell cycle control protein (crooked neck); [GO:0005515] protein binding; [PF13181] Tetratricopeptide repeat; [K12869] crooked neck; [GO:0005622] intracellular; [PF02184] HAT (Half-A-TPR) repeat; [PTHR11246:SF3] CROOKED NECK PROTEIN 139.26 0.6859 110 Mapoly0102s0024 [GO:0006355] regulation of transcription, DNA-dependent; [PF14443] DBC1; [KOG3227] Calcium-responsive transcription coactivator; [PTHR14304] P30 DBC PROTEIN 140.37 0.7084 111 Mapoly0006s0154 - 143.25 0.6700 112 Mapoly0060s0063 - 143.50 0.6707 113 Mapoly0091s0056 [PF05918] Apoptosis inhibitory protein 5 (API5); [KOG2213] Apoptosis inhibitor 5/fibroblast growth factor 2-interacting factor 2, and related proteins; [PTHR12758] APOPTOSIS INHIBITOR 5-RELATED 145.31 0.6855 114 Mapoly0009s0039 [GO:0030915] Smc5-Smc6 complex; [KOG2866] Uncharacterized conserved protein; [PTHR16140:SF0] SUBFAMILY NOT NAMED; [PTHR16140] UNCHARACTERIZED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08743] Nse4 C-terminal 146.94 0.6937 115 Mapoly0027s0013 [KOG4487] Uncharacterized conserved protein; [PF09696] Ctf8; [K11270] chromosome transmission fidelity protein 8 148.27 0.6915 116 Mapoly0030s0102 [PF08317] Spc7 kinetochore protein 148.80 0.6966 117 Mapoly0020s0135 [PF03941] Inner centromere protein, ARK binding region; [PTHR13142:SF1] INCENP; [KOG1295] Nonsense-mediated decay protein Upf3; [PTHR13142] INNER CENTROMERE PROTEIN 149.01 0.6913 118 Mapoly0081s0047 [PF00773] RNB domain; [PF13638] PIN domain; [3.1.13.-] Exoribonucleases producing 5'-phosphomonoesters.; [K12585] exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]; [PTHR23355] RIBONUCLEASE; [KOG2102] Exosomal 3'-5' exoribonuclease complex, subunit Rrp44/Dis3 149.57 0.6749 119 Mapoly0052s0095 [GO:0005643] nuclear pore; [PTHR31344:SF0] SUBFAMILY NOT NAMED; [K14310] nuclear pore complex protein Nup205; [PF11894] Protein of unknown function (DUF3414); [PTHR31344] FAMILY NOT NAMED; [KOG1835] Uncharacterized conserved protein 149.88 0.6775 120 Mapoly0022s0008 [PTHR22808] NCL1(YEAST)-RELATED NOL1/NOP2/FMU(SUN) DOMAIN-CONTAINING; [PF01189] NOL1/NOP2/sun family; [KOG2198] tRNA cytosine-5-methylases and related enzymes of the NOL1/NOP2/sun superfamily; [PTHR22808:SF1] PUTATIVE METHYLTRANSFERASE NCL1(YEAST)-RELATED 150.60 0.6816 121 Mapoly0050s0019 [PF08642] Histone deacetylation protein Rxt3; [KOG4843] Uncharacterized conserved protein 152.91 0.6681 122 Mapoly0045s0076 - 153.80 0.6324 123 Mapoly0029s0012 [GO:0005524] ATP binding; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [KOG0329] ATP-dependent RNA helicase; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding 154.96 0.6922 124 Mapoly0087s0011 [GO:0005634] nucleus; [PF07557] Shugoshin C terminus; [GO:0000775] chromosome, centromeric region; [GO:0045132] meiotic chromosome segregation 157.97 0.6787 125 Mapoly0004s0056 [PTHR23424] SERUM AMYLOID A 158.47 0.6582 126 Mapoly0014s0073 [KOG1663] O-methyltransferase; [GO:0008171] O-methyltransferase activity; [PTHR10509] O-METHYLTRANSFERASE-RELATED; [PF01596] O-methyltransferase 159.30 0.6451 127 Mapoly0131s0021 [PTHR13119] FAMILY NOT NAMED; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 159.83 0.5835 128 Mapoly0031s0131 - 161.83 0.5540 129 Mapoly0143s0029 - 161.93 0.6386 130 Mapoly0147s0014 [PTHR14790] FAMILY NOT NAMED; [PF08585] Domain of unknown function (DUF1767) 162.27 0.6780 131 Mapoly0140s0032 [PTHR12748] ORIGIN RECOGNITION COMPLEX SUBUNIT 3; [PTHR12748:SF0] SUBFAMILY NOT NAMED; [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02605] origin recognition complex subunit 3; [PF07034] Origin recognition complex (ORC) subunit 3 N-terminus; [KOG2538] Origin recognition complex, subunit 3; [GO:0005664] nuclear origin of replication recognition complex; [PF02178] AT hook motif 163.37 0.6907 132 Mapoly0061s0120 [PTHR13269] UNCHARACTERIZED; [PTHR13269:SF6] SUBFAMILY NOT NAMED; [PF09531] Nucleoporin protein Ndc1-Nup 164.23 0.6810 133 Mapoly0074s0003 [GO:0003677] DNA binding; [PF12254] DNA polymerase alpha subunit p180 N terminal; [GO:0006260] DNA replication; [GO:0001882] nucleoside binding; [K02320] DNA polymerase alpha subunit A [EC:2.7.7.7]; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0006270] DNA replication initiation; [PF08996] DNA Polymerase alpha zinc finger; [KOG0970] DNA polymerase alpha, catalytic subunit; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT 165.90 0.6683 134 Mapoly0010s0152 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PTHR13561:SF5] DNA REPLICATION REGULATOR DPB11; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 167.04 0.6816 135 Mapoly0001s0406 [GO:0000922] spindle pole; [KOG2000] Gamma-tubulin complex, DGRIP91/SPC98 component; [PF04130] Spc97 / Spc98 family; [GO:0005856] cytoskeleton; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [GO:0007020] microtubule nucleation; [PTHR19302:SF14] GAMMA-TUBULIN COMPLEX COMPONENT 3 (GCP-3) 168.00 0.6656 136 Mapoly0007s0100 [PTHR15828] CYTOKINE RECEPTOR-LIKE FACTOR 3 168.41 0.6797 137 Mapoly0051s0067 [PF00651] BTB/POZ domain; [PTHR24411] FAMILY NOT NAMED; [PF00917] MATH domain; [GO:0005515] protein binding; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 168.71 0.6430 138 Mapoly0014s0195 [PTHR10641:SF17] CELL DIVISION CYCLE 5-LIKE PROTEIN; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [PF13921] Myb-like DNA-binding domain; [PF11831] pre-mRNA splicing factor component; [K12860] pre-mRNA-splicing factor CDC5/CEF1 168.88 0.6739 139 Mapoly0139s0008 [PF14929] TAF RNA Polymerase I subunit A 169.01 0.6500 140 Mapoly0039s0120 [KOG1805] DNA replication helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PTHR10887:SF14] DNA2-LIKE HELICASE; [3.6.4.12] DNA helicase.; [PF13086] AAA domain; [GO:0033567] DNA replication, Okazaki fragment processing; [PF01930] Domain of unknown function DUF83; [GO:0017108] 5'-flap endonuclease activity; [GO:0043142] single-stranded DNA-dependent ATPase activity; [PF13087] AAA domain; [PF08696] DNA replication factor Dna2; [K10742] DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12] 170.71 0.6640 141 Mapoly0078s0037 [KOG0987] DNA helicase PIF1/RRM3; [PF05970] PIF1-like helicase; [GO:0006281] DNA repair; [PTHR23274] DNA HELICASE-RELATED; [GO:0003678] DNA helicase activity; [GO:0000723] telomere maintenance 172.96 0.6621 142 Mapoly0008s0107 [K12852] 116 kDa U5 small nuclear ribonucleoprotein component; [PF00009] Elongation factor Tu GTP binding domain; [PF00679] Elongation factor G C-terminus; [GO:0003924] GTPase activity; [PTHR23115] TRANSLATION FACTOR; [PTHR23115:SF5] 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT; [PF03764] Elongation factor G, domain IV; [KOG0468] U5 snRNP-specific protein; [GO:0005525] GTP binding; [PF03144] Elongation factor Tu domain 2 173.07 0.6851 143 Mapoly0029s0111 [PTHR22836] WD40 REPEAT PROTEIN; [GO:0005515] protein binding; [KOG0284] Polyadenylation factor I complex, subunit PFS2; [PF00400] WD domain, G-beta repeat 173.20 0.6387 144 Mapoly0061s0078 [KOG1361] Predicted hydrolase involved in interstrand cross-link repair; [PTHR23240] DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; [PF12706] Beta-lactamase superfamily domain; [PF07522] DNA repair metallo-beta-lactamase; [PF00536] SAM domain (Sterile alpha motif) 173.93 0.6738 145 Mapoly0003s0175 [KOG1105] Transcription elongation factor TFIIS/Cofactor of enhancer-binding protein Sp1; [PF07500] Transcription factor S-II (TFIIS), central domain; [GO:0008270] zinc ion binding; [PTHR11477] TRANSCRIPTION ELONGATION FACTOR S-II; [GO:0006351] transcription, DNA-dependent; [GO:0003676] nucleic acid binding; [K03145] transcription elongation factor S-II; [PF01096] Transcription factor S-II (TFIIS) 174.24 0.6531 146 Mapoly0056s0030 [KOG1040] Polyadenylation factor I complex, subunit, Yth1 (CPSF subunit); [PTHR12357] YTH (YT521-B HOMOLOGY) DOMAIN-CONTAINING; [PF04146] YT521-B-like domain; [PTHR12357:SF3] SPLICING FACTOR YT521-B 174.30 0.6495 147 Mapoly0120s0004 [PF00488] MutS domain V; [GO:0005524] ATP binding; [K08735] DNA mismatch repair protein MSH2; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PTHR11361:SF35] MUTS HOMOLOG 2, MSH2; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III; [KOG0219] Mismatch repair ATPase MSH2 (MutS family); [PF05190] MutS family domain IV 174.48 0.6763 148 Mapoly0052s0032 [GO:0006333] chromatin assembly or disassembly; [PF04729] ASF1 like histone chaperone; [K10753] histone chaperone ASF1; [PTHR12040] ANTI-SILENCING PROTEIN 1; [GO:0005634] nucleus 175.63 0.6493 149 Mapoly0010s0036 [KOG2002] TPR-containing nuclear phosphoprotein that regulates K(+) uptake; [PF07719] Tetratricopeptide repeat; [PTHR14027:SF2] TPR REPEAT NUCLEAR PHOSPHOPROTEIN; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13174] Tetratricopeptide repeat; [PF13181] Tetratricopeptide repeat; [PF13424] Tetratricopeptide repeat; [PTHR14027] TPR REPEAT NUCLEAR PHOSPHOPROTEIN/CTR9; [PF00515] Tetratricopeptide repeat 175.86 0.6898 150 Mapoly0016s0079 [GO:0005524] ATP binding; [KOG2680] DNA helicase TIP49, TBP-interacting protein; [3.6.4.12] DNA helicase.; [PF06068] TIP49 C-terminus; [GO:0043141] ATP-dependent 5'-3' DNA helicase activity; [K11338] RuvB-like protein 2 [EC:3.6.4.12]; [GO:0003678] DNA helicase activity; [PTHR11093] RUVB-RELATED REPTIN AND PONTIN; [PTHR11093:SF2] RUVB-LIKE 2 (REPTIN) 177.76 0.6741 151 Mapoly0102s0001 [K06228] fused [EC:2.7.11.1]; [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR22983:SF6] MAPK KINASE 2-RELATED; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [KOG0598] Ribosomal protein S6 kinase and related proteins; [PF13646] HEAT repeats 181.51 0.6793 152 Mapoly0013s0040 [GO:0005524] ATP binding; [KOG0359] Chaperonin complex component, TCP-1 zeta subunit (CCT6); [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family 181.71 0.6690 153 Mapoly0001s0557 [PTHR11142] PSEUDOURIDYLATE SYNTHASE; [GO:0003723] RNA binding; [K06173] tRNA pseudouridine synthase A [EC:5.4.99.12]; [GO:0001522] pseudouridine synthesis; [KOG2553] Pseudouridylate synthase; [GO:0009451] RNA modification; [PF01416] tRNA pseudouridine synthase; [GO:0009982] pseudouridine synthase activity; [5.4.99.12] tRNA pseudouridine(38-40) synthase. 181.93 0.6554 154 Mapoly0006s0290 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR10670:SF0] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A; [GO:0000166] nucleotide binding; [GO:0008270] zinc ion binding; [2.7.7.7] DNA-directed DNA polymerase.; [KOG1798] DNA polymerase epsilon, catalytic subunit A; [PF08490] Domain of unknown function (DUF1744); [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF00136] DNA polymerase family B; [GO:0008622] epsilon DNA polymerase complex; [K02324] DNA polymerase epsilon subunit 1 [EC:2.7.7.7]; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10670] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A 182.26 0.6815 155 Mapoly0084s0055 [GO:0005524] ATP binding; [KOG0744] AAA+-type ATPase; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23077] AAA-FAMILY ATPASE 182.29 0.6674 156 Mapoly0080s0039 [PTHR15081] NUCLEAR AUTOANTIGENIC SPERM PROTEIN (NASP)-RELATED; [PF13414] TPR repeat; [PF10516] SHNi-TPR 184.17 0.6734 157 Mapoly0001s0188 - 184.52 0.6704 158 Mapoly0052s0123 [PTHR12616] VACUOLAR PROTEIN SORTING VPS41 184.73 0.6496 159 Mapoly0073s0063 [GO:0016020] membrane; [GO:0005524] ATP binding; [GO:0017038] protein import; [PF07516] SecA Wing and Scaffold domain; [PTHR30612] SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM; [PF07517] SecA DEAD-like domain; [PF01043] SecA preprotein cross-linking domain; [K03070] preprotein translocase subunit SecA 184.90 0.5889 160 Mapoly0158s0003 [PF13921] Myb-like DNA-binding domain 186.10 0.6159 161 Mapoly0005s0264 [PF03725] 3' exoribonuclease family, domain 2; [PTHR11097] EXOSOME COMPLEX EXONUCLEASE (RIBOSOMAL RNA PROCESSING PROTEIN); [KOG1614] Exosomal 3'-5' exoribonuclease complex, subunit Rrp45; [PF01138] 3' exoribonuclease family, domain 1 187.31 0.6833 162 Mapoly0027s0185 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF39] CDC2-RELATED PROTEIN KINASE; [KOG0600] Cdc2-related protein kinase; [K08819] Cdc2-related kinase, arginine/serine-rich [EC:2.7.11.22]; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 188.10 0.6664 163 Mapoly0001s0449 [GO:0006355] regulation of transcription, DNA-dependent; [PF04153] NOT2 / NOT3 / NOT5 family; [GO:0005634] nucleus; [K12605] CCR4-NOT transcription complex subunit 2; [PTHR23326] CCR4 NOT-RELATED 190.73 0.6285 164 Mapoly0043s0047 [GO:0005515] protein binding; [PF00612] IQ calmodulin-binding motif; [PTHR25069] FAMILY NOT NAMED; [PF00307] Calponin homology (CH) domain 191.26 0.6701 165 Mapoly0050s0010 [KOG2829] E2F-like protein; [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [PTHR12548] TRANSCRIPTION FACTOR DP; [PF08781] Transcription factor DP; [GO:0007049] cell cycle 192.25 0.6072 166 Mapoly0036s0123 [GO:0000922] spindle pole; [PTHR19302:SF13] GAMMA-TUBULIN COMPLEX COMPONENT 2 (GCP-2); [PF04130] Spc97 / Spc98 family; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [KOG2001] Gamma-tubulin complex, DGRIP84/SPC97 component 192.69 0.6833 167 Mapoly0135s0033 [PF07093] SGT1 protein; [KOG2406] MADS box transcription factor; [PTHR13060] SGT1 PROTEIN (HSGT1) (SUPPRESSOR OF GCR2) 193.21 0.6628 168 Mapoly0213s0004 [PTHR24012] FAMILY NOT NAMED; [KOG0226] RNA-binding proteins; [GO:0003676] nucleic acid binding; [PTHR24012:SF41] SUBFAMILY NOT NAMED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 194.30 0.6341 169 Mapoly0003s0120 [GO:0003677] DNA binding; [PTHR12708:SF0] SUBFAMILY NOT NAMED; [GO:0006260] DNA replication; [PF12213] DNA polymerases epsilon N terminal; [2.7.7.7] DNA-directed DNA polymerase.; [PTHR12708] DNA POLYMERASE EPSILON SUBUNIT B; [KOG3818] DNA polymerase epsilon, subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [GO:0003887] DNA-directed DNA polymerase activity; [K02325] DNA polymerase epsilon subunit 2 [EC:2.7.7.7] 195.13 0.6594 170 Mapoly0081s0071 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [PF00628] PHD-finger; [GO:0005515] protein binding; [PF12738] twin BRCT domain; [GO:0046872] metal ion binding 197.20 0.6656 171 Mapoly0034s0119 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 197.69 0.6742 172 Mapoly0063s0076 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF0] CELL DIVISION PROTEIN KINASE 7; [K02202] cyclin-dependent kinase 7 [EC:2.7.11.22]; [KOG0659] Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 203.17 0.6500 173 Mapoly0050s0101 [3.4.21.48] Cerevisin.; [K01336] cerevisin [EC:3.4.21.48]; [GO:0004252] serine-type endopeptidase activity; [PF00082] Subtilase family; [PF00090] Thrombospondin type 1 domain; [PF00053] Laminin EGF-like (Domains III and V); [GO:0006508] proteolysis; [PTHR10795] PROPROTEIN CONVERTASE SUBTILISIN/KEXIN 203.50 0.6569 174 Mapoly0009s0067 [PTHR31789] FAMILY NOT NAMED 203.53 0.6622 175 Mapoly0033s0145 - 203.65 0.6606 176 Mapoly0119s0054 [GO:0008641] small protein activating enzyme activity; [GO:0005524] ATP binding; [PF09358] Ubiquitin-activating enzyme e1 C-terminal domain; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [PTHR10953:SF4] UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 1 (UBIQUITIN-ACTIVATING ENZYME E1) 204.80 0.6740 177 Mapoly0147s0033 [PF07738] Sad1 / UNC-like C-terminal; [PTHR12911] SAD1/UNC-84-LIKE PROTEIN-RELATED; [KOG2687] Spindle pole body protein, contains UNC-84 domain 205.19 0.6633 178 Mapoly0005s0138 - 206.30 0.6581 179 Mapoly0002s0169 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [K06632] wee1-like protein kinase [EC:2.7.11.1]; [PTHR11042] EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE (EIF2-ALPHA KINASE)-RELATED; [KOG0601] Cyclin-dependent kinase WEE1 206.56 0.6608 180 Mapoly0042s0047 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF65] DNA REPAIR AND RECOMBINATION PROTEIN RAD26-RELATED 206.98 0.6699 181 Mapoly0043s0050 [PTHR23019:SF0] SUBFAMILY NOT NAMED; [K14314] nuclear pore complex protein Nup210; [PF02368] Bacterial Ig-like domain (group 2); [PTHR23019] NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED; [KOG1833] Nuclear pore complex, gp210 component 207.80 0.6583 182 Mapoly0009s0015 [PF00078] Reverse transcriptase (RNA-dependent DNA polymerase); [PTHR12066] TELOMERASE REVERSE TRANSCRIPTASE; [GO:0003964] RNA-directed DNA polymerase activity; [K11126] telomerase reverse transcriptase [EC:2.7.7.49]; [PTHR12066:SF0] SUBFAMILY NOT NAMED; [2.7.7.49] RNA-directed DNA polymerase.; [PF12009] Telomerase ribonucleoprotein complex - RNA binding domain; [KOG1005] Telomerase catalytic subunit/reverse transcriptase TERT 207.92 0.6808 183 Mapoly0045s0042 [KOG2475] CDC45 (cell division cycle 45)-like protein; [GO:0006270] DNA replication initiation; [PF02724] CDC45-like protein; [PTHR10507:SF0] CDC45-RELATED PROTEIN; [PTHR10507] CDC45-RELATED PROTEIN; [K06628] cell division control protein 45 208.50 0.6672 184 Mapoly0070s0034 [KOG0108] mRNA cleavage and polyadenylation factor I complex, subunit RNA15; [PF14327] Hinge domain of cleavage stimulation factor subunit 2; [PTHR23139:SF8] RNA RECOGNITION MOTIF CONTAINING PROTEIN; [PTHR23139] RNA-BINDING PROTEIN; [GO:0003676] nucleic acid binding; [K14407] cleavage stimulation factor subunit 2; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 210.04 0.6600 185 Mapoly0051s0073 [PF14675] FANCI solenoid 1; [PTHR21818:SF0] SUBFAMILY NOT NAMED; [PF14680] FANCI helical domain 2; [KOG4553] Uncharacterized conserved protein; [K10895] fanconi anemia group I protein; [PF14679] FANCI helical domain 1; [GO:0006281] DNA repair; [PF14678] FANCI solenoid 4; [PTHR21818] BC025462 PROTEIN; [PF14676] FANCI solenoid 2 211.07 0.6643 186 Mapoly0066s0020 [PF13812] Pentatricopeptide repeat domain; [PF12854] PPR repeat; [PF01535] PPR repeat; [PTHR24015] FAMILY NOT NAMED; [PF13041] PPR repeat family 211.83 0.6618 187 Mapoly0006s0052 [GO:0003723] RNA binding; [GO:0004523] ribonuclease H activity; [PF01351] Ribonuclease HII; [PTHR10954] RIBONUCLEASE H2 SUBUNIT A; [K10743] ribonuclease H2 subunit A [EC:3.1.26.4]; [3.1.26.4] Ribonuclease H.; [PTHR10954:SF7] RIBONUCLEASE H2 SUBUNIT A; [KOG2299] Ribonuclease HI 212.72 0.6402 188 Mapoly0085s0026 [PF00533] BRCA1 C Terminus (BRCT) domain; [PTHR23196] PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN 215.33 0.6599 189 Mapoly0024s0107 [PF07719] Tetratricopeptide repeat; [GO:0005515] protein binding; [PF13414] TPR repeat; [K03350] anaphase-promoting complex subunit 3; [KOG1126] DNA-binding cell division cycle control protein; [PF13181] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat; [PTHR12558] CELL DIVISION CYCLE 16,23,27; [PTHR12558:SF11] CELL DIVISION CYCLE 27; [PF12895] Anaphase-promoting complex, cyclosome, subunit 3 216.17 0.6494 190 Mapoly0003s0063 [GO:0005524] ATP binding; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24361:SF129] MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE; [GO:0006468] protein phosphorylation; [PTHR24361] MITOGEN-ACTIVATED KINASE KINASE KINASE 216.36 0.6587 191 Mapoly0002s0233 [GO:0008168] methyltransferase activity; [KOG2899] Predicted methyltransferase; [PF06859] Bicoid-interacting protein 3 (Bin3); [PTHR12315:SF0] SUBFAMILY NOT NAMED; [PTHR12315] BICOID-INTERACTING PROTEIN RELATED 216.43 0.6353 192 Mapoly0004s0169 [GO:0003677] DNA binding; [GO:0006338] chromatin remodeling; [GO:0005524] ATP binding; [PF09110] HAND; [K11654] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]; [GO:0043044] ATP-dependent chromatin remodeling; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [GO:0005634] nucleus; [PTHR10799:SF73] ISWI CHROMATIN-REMODELING COMPLEX ATPASE ISW1; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [KOG0385] Chromatin remodeling complex WSTF-ISWI, small subunit; [GO:0003676] nucleic acid binding; [GO:0031491] nucleosome binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [PF09111] SLIDE 216.48 0.6734 193 Mapoly0035s0035 [PTHR11132] SOLUTE CARRIER FAMILY 35; [KOG1443] Predicted integral membrane protein 218.69 0.5929 194 Mapoly0015s0045 [KOG0533] RRM motif-containing protein; [PTHR19965] RNA AND EXPORT FACTOR BINDING PROTEIN; [K12881] THO complex subunit 4; [PF13865] C-terminal duplication domain of Friend of PRMT1; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 221.00 0.6522 195 Mapoly0076s0033 [PF10444] Nbl1 / Borealin N terminal 221.46 0.6546 196 Mapoly0095s0037 [PTHR14003:SF1] YY1-RELATED; [PF13465] Zinc-finger double domain; [PTHR14003] TRANSCRIPTIONAL REPRESSOR PROTEIN YY; [PF13894] C2H2-type zinc finger 221.92 0.6388 197 Mapoly0099s0028 [GO:0005524] ATP binding; [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family; [KOG0360] Chaperonin complex component, TCP-1 alpha subunit (CCT1) 223.19 0.6463 198 Mapoly0042s0086 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K08737] DNA mismatch repair protein MSH6; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PTHR11361:SF31] MUTS HOMOLOG 6, MSH6; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 223.43 0.6611 199 Mapoly0155s0010 [KOG0319] WD40-repeat-containing subunit of the 18S rRNA processing complex; [PF08625] Utp13 specific WD40 associated domain; [PTHR19854:SF15] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [GO:0006364] rRNA processing; [K14555] U3 small nucleolar RNA-associated protein 13; [GO:0032040] small-subunit processome; [PTHR19854] TRANSDUCIN BETA-LIKE 3; [PF00400] WD domain, G-beta repeat 223.45 0.6515 200 Mapoly0001s0044 [PTHR31110] FAMILY NOT NAMED 223.78 0.6660