Guide Gene
- Gene ID
- Mapoly0013s0006
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [GO:0008270] zinc ion binding; [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PTHR23336] ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3.; [PF07496] CW-type Zinc Finger
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0013s0006 [GO:0008270] zinc ion binding; [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PTHR23336] ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3.; [PF07496] CW-type Zinc Finger 0.00 1.0000 1 Mapoly0092s0032 [PTHR22597] POLYCOMB GROUP PROTEIN; [PTHR22597:SF0] SUBFAMILY NOT NAMED; [PF09733] VEFS-Box of polycomb protein 3.00 0.8481 2 Mapoly0094s0033 [GO:0016567] protein ubiquitination; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [KOG0314] Predicted E3 ubiquitin ligase; [GO:0005634] nucleus; [PF08783] DWNN domain; [GO:0003676] nucleic acid binding; [GO:0004842] ubiquitin-protein ligase activity; [PTHR15439] RETINOBLASTOMA-BINDING PROTEIN 6; [PF04564] U-box domain 3.61 0.7981 3 Mapoly0001s0449 [GO:0006355] regulation of transcription, DNA-dependent; [PF04153] NOT2 / NOT3 / NOT5 family; [GO:0005634] nucleus; [K12605] CCR4-NOT transcription complex subunit 2; [PTHR23326] CCR4 NOT-RELATED 4.36 0.7903 4 Mapoly0031s0090 [KOG0379] Kelch repeat-containing proteins; [PF13418] Galactose oxidase, central domain; [PTHR23244] KELCH REPEAT DOMAIN; [PF13415] Galactose oxidase, central domain 5.29 0.8440 5 Mapoly0033s0098 [PTHR16047] RFWD3 PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PTHR16047:SF7] RFWD3 PROTEIN-RELATED; [KOG1645] RING-finger-containing E3 ubiquitin ligase 5.66 0.8257 6 Mapoly0113s0034 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PF01698] Floricaula / Leafy protein 6.93 0.8144 7 Mapoly0042s0123 [K12875] apoptotic chromatin condensation inducer in the nucleus; [GO:0003676] nucleic acid binding; [PTHR14127] APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; [PF02037] SAP domain 7.55 0.8342 8 Mapoly0015s0126 [GO:0008641] small protein activating enzyme activity; [GO:0005524] ATP binding; [K10685] ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19]; [KOG2013] SMT3/SUMO-activating complex, catalytic component UBA2; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [PF14732] Ubiquitin/SUMO-activating enzyme ubiquitin-like domain 7.75 0.8228 9 Mapoly0165s0024 [GO:0006338] chromatin remodeling; [GO:0043968] histone H2A acetylation; [PF00249] Myb-like DNA-binding domain; [K11324] DNA methyltransferase 1-associated protein 1; [GO:0043967] histone H4 acetylation; [KOG2656] DNA methyltransferase 1-associated protein-1; [GO:0003682] chromatin binding; [PTHR12855] FAMILY NOT NAMED; [GO:0035267] NuA4 histone acetyltransferase complex; [GO:0006281] DNA repair; [PTHR12855:SF10] SUBFAMILY NOT NAMED 9.49 0.8119 10 Mapoly0036s0107 [K09422] myb proto-oncogene protein, plant; [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding; [PF13921] Myb-like DNA-binding domain 16.52 0.8197 11 Mapoly0031s0131 - 17.55 0.6413 12 Mapoly0051s0023 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III 18.97 0.8197 13 Mapoly0070s0053 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF09382] RQC domain; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [K10901] bloom syndrome protein [EC:3.6.4.12]; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 20.45 0.8098 14 Mapoly0004s0056 [PTHR23424] SERUM AMYLOID A 21.93 0.7593 15 Mapoly0001s0472 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED 22.36 0.8100 16 Mapoly0105s0060 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [K12898] heterogeneous nuclear ribonucleoprotein F/H; [KOG4211] Splicing factor hnRNP-F and related RNA-binding proteins; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED 24.98 0.8070 17 Mapoly0001s0378 [PTHR32086] FAMILY NOT NAMED; [K10891] fanconi anemia group D2 protein; [GO:0006281] DNA repair; [KOG4712] Uncharacterized conserved protein; [PF14631] Fanconi anaemia protein FancD2 nuclease 26.08 0.7919 18 Mapoly0002s0093 [PTHR24012] FAMILY NOT NAMED; [KOG4205] RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1; [K12741] heterogeneous nuclear ribonucleoprotein A1/A3; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 26.74 0.7445 19 Mapoly0027s0147 [PTHR12585] SCC1 / RAD21 FAMILY MEMBER; [PF04824] Conserved region of Rad21 / Rec8 like protein; [GO:0005515] protein binding; [PF04825] N terminus of Rad21 / Rec8 like protein; [K06670] cohesin complex subunit SCC1; [GO:0000228] nuclear chromosome; [KOG1213] Sister chromatid cohesion complex Cohesin, subunit RAD21/SCC1 28.14 0.7919 20 Mapoly0030s0101 [GO:0042393] histone binding; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [K11647] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-]; [KOG0386] Chromatin remodeling complex SWI/SNF, component SWI2 and related ATPases (DNA/RNA helicase superfamily); [PTHR10799:SF209] GLOBAL TRANSCRIPTION ACTIVATOR SNF2L2 (ATP-DEPENDENT HELICASE SMARCA2); [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [PF14619] Snf2-ATP coupling, chromatin remodelling complex 30.20 0.7932 21 Mapoly0036s0123 [GO:0000922] spindle pole; [PTHR19302:SF13] GAMMA-TUBULIN COMPLEX COMPONENT 2 (GCP-2); [PF04130] Spc97 / Spc98 family; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [KOG2001] Gamma-tubulin complex, DGRIP84/SPC97 component 35.50 0.7974 22 Mapoly0131s0010 [PTHR15921:SF3] SUBFAMILY NOT NAMED; [KOG2071] mRNA cleavage and polyadenylation factor I/II complex, subunit Pcf11; [PF04818] RNA polymerase II-binding domain.; [PTHR15921] PRE-MRNA CLEAVAGE COMPLEX II 35.50 0.7949 23 Mapoly0004s0286 [PTHR12663:SF0] SUBFAMILY NOT NAMED; [K11267] sister chromatid cohesion protein PDS5; [PTHR12663] ANDROGEN INDUCED INHIBITOR OF PROLIFERATION (AS3) / PDS5-RELATED; [KOG1525] Sister chromatid cohesion complex Cohesin, subunit PDS5 41.50 0.7863 24 Mapoly0047s0105 [KOG4308] LRR-containing protein; [PTHR10098] RAPSYN-RELATED; [PF13516] Leucine Rich repeat; [PF13414] TPR repeat 42.21 0.7823 25 Mapoly0113s0037 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [KOG2577] Transcription factor E2F/dimerization partner (TDP); [PTHR12081] TRANSCRIPTION FACTOR E2F 43.71 0.7584 26 Mapoly0098s0013 [KOG1634] Predicted transcription factor DATF1, contains PHD and TFS2M domains; [PF07500] Transcription factor S-II (TFIIS), central domain; [PTHR11477] TRANSCRIPTION ELONGATION FACTOR S-II; [GO:0006351] transcription, DNA-dependent; [PF07744] SPOC domain 45.90 0.7559 27 Mapoly0051s0016 [PF13831] PHD-finger; [PF05964] F/Y-rich N-terminus; [GO:0005515] protein binding; [PF13832] PHD-zinc-finger like domain; [PF00856] SET domain; [PTHR13793] PHD FINGER PROTEINS; [PF00855] PWWP domain; [GO:0005634] nucleus; [PF05965] F/Y rich C-terminus 49.96 0.7766 28 Mapoly0028s0116 [PTHR22884] SET DOMAIN PROTEINS 50.38 0.7724 29 Mapoly0006s0290 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR10670:SF0] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A; [GO:0000166] nucleotide binding; [GO:0008270] zinc ion binding; [2.7.7.7] DNA-directed DNA polymerase.; [KOG1798] DNA polymerase epsilon, catalytic subunit A; [PF08490] Domain of unknown function (DUF1744); [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF00136] DNA polymerase family B; [GO:0008622] epsilon DNA polymerase complex; [K02324] DNA polymerase epsilon subunit 1 [EC:2.7.7.7]; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10670] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A 51.43 0.7785 30 Mapoly0019s0028 [PTHR24011] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [KOG0117] Heterogeneous nuclear ribonucleoprotein R (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 53.39 0.7493 31 Mapoly0209s0008 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF67] DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 53.67 0.7897 32 Mapoly0005s0161 [GO:0003677] DNA binding; [PTHR13451:SF0] SUBFAMILY NOT NAMED; [3.1.22.-] Endodeoxyribonucleases producing other than 5'-phosphomonoesters.; [K08991] crossover junction endonuclease MUS81 [EC:3.1.22.-]; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PF02732] ERCC4 domain 53.72 0.7292 33 Mapoly0009s0067 [PTHR31789] FAMILY NOT NAMED 54.00 0.7454 34 Mapoly0074s0020 - 54.48 0.6066 35 Mapoly0055s0120 - 55.08 0.7573 36 Mapoly0075s0051 [GO:0006355] regulation of transcription, DNA-dependent; [PF02309] AUX/IAA family; [GO:0005634] nucleus; [PTHR31384] FAMILY NOT NAMED 56.99 0.7661 37 Mapoly0007s0100 [PTHR15828] CYTOKINE RECEPTOR-LIKE FACTOR 3 57.97 0.7579 38 Mapoly0030s0009 [PF00505] HMG (high mobility group) box; [KOG0526] Nucleosome-binding factor SPN, POB3 subunit; [PF03531] Structure-specific recognition protein (SSRP1); [PTHR13711:SF39] SUBFAMILY NOT NAMED; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [PF08512] Histone chaperone Rttp106-like; [K09272] structure-specific recognition protein 1 57.97 0.7569 39 Mapoly0102s0001 [K06228] fused [EC:2.7.11.1]; [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR22983:SF6] MAPK KINASE 2-RELATED; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [KOG0598] Ribosomal protein S6 kinase and related proteins; [PF13646] HEAT repeats 58.45 0.7722 40 Mapoly0067s0068 [KOG2266] Chromatin-associated protein Dek and related proteins, contains SAP DNA binding domain; [PTHR13468:SF1] DEK ONCOGENE; [PF08766] DEK C terminal domain; [PTHR13468] DEK PROTEIN 59.46 0.7605 41 Mapoly0008s0081 [PTHR21286] NUCLEAR PORE COMPLEX PROTEIN NUP160; [K14303] nuclear pore complex protein Nup160; [KOG4521] Nuclear pore complex, Nup160 component; [PF11715] Nucleoporin Nup120/160 60.74 0.7626 42 Mapoly0061s0078 [KOG1361] Predicted hydrolase involved in interstrand cross-link repair; [PTHR23240] DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; [PF12706] Beta-lactamase superfamily domain; [PF07522] DNA repair metallo-beta-lactamase; [PF00536] SAM domain (Sterile alpha motif) 61.02 0.7480 43 Mapoly0005s0067 [PTHR15242:SF0] SUBFAMILY NOT NAMED; [PTHR15242] SPLICING FACTOR, ARGININE/SERINE-RICH 2,RNAP C-TERM INTERACTING PROTEIN; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 61.87 0.7617 44 Mapoly0003s0057 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination 64.09 0.7727 45 Mapoly0153s0011 [PF13871] Helicase_C-like; [GO:0006355] regulation of transcription, DNA-dependent; [KOG1513] Nuclear helicase MOP-3/SNO (DEAD-box superfamily); [PTHR12706] STRAWBERRY NOTCH-RELATED; [PF13872] P-loop containing NTP hydrolase pore-1 64.34 0.7596 46 Mapoly0011s0202 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain 64.61 0.7753 47 Mapoly0074s0043 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [GO:0003729] mRNA binding 67.14 0.7508 48 Mapoly0052s0086 [PF05641] Agenet domain; [PTHR31917] FAMILY NOT NAMED 68.37 0.7586 49 Mapoly0062s0114 [KOG1187] Serine/threonine protein kinase; [PF07714] Protein tyrosine kinase; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 68.55 0.7027 50 Mapoly0023s0143 [GO:0005524] ATP binding; [PTHR23073] 26S PROTEASE REGULATORY SUBUNIT; [PTHR23073:SF18] SUBFAMILY NOT NAMED; [PF00004] ATPase family associated with various cellular activities (AAA) 69.83 0.7543 51 Mapoly0005s0151 [KOG2688] Transcription-associated recombination protein - Thp1p; [PTHR12732] UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING; [GO:0005515] protein binding; [PTHR12732:SF0] SUBFAMILY NOT NAMED; [PF01399] PCI domain 70.42 0.6544 52 Mapoly0113s0048 [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [KOG1408] WD40 repeat protein; [PF00400] WD domain, G-beta repeat 70.78 0.7640 53 Mapoly0030s0102 [PF08317] Spc7 kinetochore protein 71.18 0.7610 54 Mapoly0038s0096 [PTHR12446] TESMIN/TSO1-RELATED; [PF03638] Tesmin/TSO1-like CXC domain, cysteine-rich domain 72.12 0.6420 55 Mapoly0033s0057 [2.3.1.-] Transferring groups other than amino-acyl groups.; [PTHR11076:SF1] ESTABLISHMENT OF COHESION 1 (ECO1) HOMOLOG; [PF13880] ESCO1/2 acetyl-transferase; [PF13878] zinc-finger of acetyl-transferase ESCO; [KOG3014] Protein involved in establishing cohesion between sister chromatids during DNA replication; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [K11268] N-acetyltransferase [EC:2.3.1.-] 72.44 0.7619 56 Mapoly0014s0195 [PTHR10641:SF17] CELL DIVISION CYCLE 5-LIKE PROTEIN; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [PF13921] Myb-like DNA-binding domain; [PF11831] pre-mRNA splicing factor component; [K12860] pre-mRNA-splicing factor CDC5/CEF1 73.27 0.7389 57 Mapoly0063s0006 [KOG2217] U4/U6.U5 snRNP associated protein; [K11984] U4/U6.U5 tri-snRNP-associated protein 1; [PTHR14152:SF5] SUBFAMILY NOT NAMED; [PTHR14152] SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES; [PF03343] SART-1 family 73.89 0.7471 58 Mapoly0068s0038 [PTHR13413] YLP MOTIF CONTAINING PROTEIN (NUCLEAR PROTEIN ZAP); [PTHR13413:SF0] SUBFAMILY NOT NAMED; [GO:0005634] nucleus 75.26 0.7511 59 Mapoly0027s0185 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF39] CDC2-RELATED PROTEIN KINASE; [KOG0600] Cdc2-related protein kinase; [K08819] Cdc2-related kinase, arginine/serine-rich [EC:2.7.11.22]; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 76.49 0.7289 60 Mapoly0005s0208 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [KOG0244] Kinesin-like protein; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [K10395] kinesin family member 4/7/21/27; [GO:0003777] microtubule motor activity 76.62 0.7416 61 Mapoly0084s0051 [2.1.1.43] Histone-lysine N-methyltransferase.; [GO:0005515] protein binding; [PF00856] SET domain; [KOG1079] Transcriptional repressor EZH1; [PTHR22884] SET DOMAIN PROTEINS; [K11430] enhancer of zeste [EC:2.1.1.43] 76.92 0.7174 62 Mapoly0072s0079 [PF11717] RNA binding activity-knot of a chromodomain; [K11339] mortality factor 4-like protein 1; [GO:0005634] nucleus; [PTHR10880] MORTALITY FACTOR 4-LIKE PROTEIN; [PF05712] MRG 78.17 0.7523 63 Mapoly0005s0051 [GO:0003723] RNA binding; [GO:0000339] RNA cap binding; [GO:0045292] mRNA cis splicing, via spliceosome; [GO:0051028] mRNA transport; [PF02854] MIF4G domain; [GO:0005515] protein binding; [KOG1104] Nuclear cap-binding complex, subunit NCBP1/CBP80; [K12882] nuclear cap-binding protein subunit 1; [GO:0016070] RNA metabolic process; [PTHR12412] CAP BINDING PROTEIN; [GO:0005846] nuclear cap binding complex; [PF09090] MIF4G like; [PF09088] MIF4G like 78.77 0.7546 64 Mapoly0044s0021 [KOG0275] Conserved WD40 repeat-containing protein; [PTHR22848] WD40 REPEAT PROTEIN; [GO:0005515] protein binding; [K13111] WD40 repeat-containing protein SMU1; [PF00400] WD domain, G-beta repeat 78.93 0.7319 65 Mapoly0044s0071 [PTHR12827] MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; [PF12859] Anaphase-promoting complex subunit 1; [K03348] anaphase-promoting complex subunit 1; [KOG1858] Anaphase-promoting complex (APC), subunit 1 (meiotic check point regulator/Tsg24); [GO:0005680] anaphase-promoting complex 79.00 0.7265 66 Mapoly0049s0040 [GO:0005524] ATP binding; [PTHR24058:SF23] DUAL-SPECIFICITY TYROSINE REGULATED PROTEIN KINASE 2; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24058] DUAL SPECIFICITY PROTEIN KINASE; [KOG0667] Dual-specificity tyrosine-phosphorylation regulated kinase; [GO:0006468] protein phosphorylation 80.19 0.7397 67 Mapoly0118s0038 - 80.80 0.7342 68 Mapoly0014s0197 [KOG4822] Predicted nuclear membrane protein involved in mRNA transport and sex determination via splicing modulation; [PTHR23185:SF0] SUBFAMILY NOT NAMED; [PTHR23185] UNCHARACTERIZED 84.00 0.7434 69 Mapoly0162s0013 [PF00929] Exonuclease; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [PTHR11361:SF34] DNA MISMATCH REPAIR PROTEIN MUTS; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [KOG0218] Mismatch repair MSH3; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 85.15 0.7411 70 Mapoly0081s0047 [PF00773] RNB domain; [PF13638] PIN domain; [3.1.13.-] Exoribonucleases producing 5'-phosphomonoesters.; [K12585] exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]; [PTHR23355] RIBONUCLEASE; [KOG2102] Exosomal 3'-5' exoribonuclease complex, subunit Rrp44/Dis3 85.16 0.7173 71 Mapoly0043s0044 [PTHR13257:SF0] SUBFAMILY NOT NAMED; [K14318] nuclear pore complex protein Nup88; [PF10168] Nuclear pore component; [KOG4460] Nuclear pore complex, Nup88/rNup84 component; [PTHR13257] NUCLEOPORIN NUP84-RELATED 86.08 0.7269 72 Mapoly0091s0014 [PTHR12596:SF1] GB DEF: T27C4.14 PROTEIN; [PTHR12596] EXPORTIN 4,7-RELATED; [KOG4541] Nuclear transport receptor exportin 4 (importin beta superfamily) 87.31 0.7269 73 Mapoly0029s0028 [PF00249] Myb-like DNA-binding domain; [GO:0005515] protein binding; [PF00569] Zinc finger, ZZ type; [GO:0003682] chromatin binding; [GO:0008270] zinc ion binding; [PF04433] SWIRM domain; [PTHR12374] TRANSCRIPTIONAL ADAPTOR 2 (ADA2)-RELATED; [KOG0457] Histone acetyltransferase complex SAGA/ADA, subunit ADA2; [K11314] transcriptional adapter 2-alpha 88.49 0.7224 74 Mapoly0054s0103 [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [3.6.4.13] RNA helicase.; [KOG0923] mRNA splicing factor ATP-dependent RNA helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [PF07717] Oligonucleotide/oligosaccharide-binding (OB)-fold; [K12813] pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:3.6.4.13] 88.68 0.7359 75 Mapoly0039s0120 [KOG1805] DNA replication helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PTHR10887:SF14] DNA2-LIKE HELICASE; [3.6.4.12] DNA helicase.; [PF13086] AAA domain; [GO:0033567] DNA replication, Okazaki fragment processing; [PF01930] Domain of unknown function DUF83; [GO:0017108] 5'-flap endonuclease activity; [GO:0043142] single-stranded DNA-dependent ATPase activity; [PF13087] AAA domain; [PF08696] DNA replication factor Dna2; [K10742] DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12] 89.33 0.7179 76 Mapoly0037s0093 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG4280] Kinesin-like protein; [PTHR24115:SF87] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [PF12711] Kinesin motor; [GO:0003777] microtubule motor activity 90.20 0.7303 77 Mapoly0007s0003 [GO:0005515] protein binding; [PTHR19918:SF8] gb def: Meiosis-specific APC/C activator protein AMA1 (Activator of meiotic APC/C protei; [KOG0305] Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits; [K03363] cell division cycle 20, cofactor of APC complex; [PTHR19918] CELL DIVISION CYCLE 20 (CDC20) (FIZZY)-RELATED; [PF00400] WD domain, G-beta repeat 91.75 0.7337 78 Mapoly0032s0010 - 91.98 0.7545 79 Mapoly0042s0086 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K08737] DNA mismatch repair protein MSH6; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PTHR11361:SF31] MUTS HOMOLOG 6, MSH6; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 92.42 0.7297 80 Mapoly0104s0010 [PTHR17204:SF5] PRE-MRNA PROCESSING PROTEIN PRP39-RELATED; [K13217] pre-mRNA-processing factor 39; [KOG1258] mRNA processing protein; [GO:0006397] mRNA processing; [GO:0005634] nucleus; [PF05843] Suppressor of forked protein (Suf); [PTHR17204] PRE-MRNA PROCESSING PROTEIN PRP39-RELATED 92.49 0.7192 81 Mapoly0001s0015 [PTHR13555] C2H2 ZINC FINGER CGI-62-RELATED 93.89 0.6934 82 Mapoly0045s0076 - 94.50 0.6670 83 Mapoly0015s0206 [PF05236] Transcription initiation factor TFIID component TAF4 family; [GO:0006352] DNA-dependent transcription, initiation; [PTHR15138] FAMILY NOT NAMED; [PF12174] RCD1-SRO-TAF4 (RST) plant domain; [GO:0005669] transcription factor TFIID complex 95.40 0.7247 84 Mapoly0060s0012 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [K11498] centromeric protein E; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 95.75 0.7469 85 Mapoly0213s0004 [PTHR24012] FAMILY NOT NAMED; [KOG0226] RNA-binding proteins; [GO:0003676] nucleic acid binding; [PTHR24012:SF41] SUBFAMILY NOT NAMED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 96.41 0.6874 86 Mapoly0013s0201 [PTHR23269:SF0] SUBFAMILY NOT NAMED; [KOG0128] RNA-binding protein SART3 (RRM superfamily); [PF05391] Lsm interaction motif; [GO:0003676] nucleic acid binding; [PTHR23269] RIBONUCLEOPROTEIN-RELATED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 96.44 0.7309 87 Mapoly0111s0003 - 99.72 0.7089 88 Mapoly0075s0058 [KOG4416] Uncharacterized conserved protein; [PF07986] Tubulin binding cofactor C; [PTHR16052] UNCHARACTERIZED 100.46 0.6841 89 Mapoly0025s0108 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity; [PF11995] Domain of unknown function (DUF3490) 100.57 0.7071 90 Mapoly0132s0002 [GO:0008270] zinc ion binding; [PF01529] DHHC palmitoyltransferase; [PTHR22883] ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN 102.24 0.6143 91 Mapoly0050s0010 [KOG2829] E2F-like protein; [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [PTHR12548] TRANSCRIPTION FACTOR DP; [PF08781] Transcription factor DP; [GO:0007049] cell cycle 104.88 0.6504 92 Mapoly0021s0077 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [KOG0796] Spliceosome subunit; [GO:0003729] mRNA binding 107.15 0.7205 93 Mapoly0135s0035 [GO:0003676] nucleic acid binding; [PF02037] SAP domain 107.24 0.7192 94 Mapoly0039s0001 - 107.47 0.7103 95 Mapoly0011s0104 [GO:0003755] peptidyl-prolyl cis-trans isomerase activity; [PTHR11071] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF00160] Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; [GO:0000413] protein peptidyl-prolyl isomerization; [KOG0546] HSP90 co-chaperone CPR7/Cyclophilin; [GO:0006457] protein folding 107.83 0.6934 96 Mapoly0034s0011 [PF09133] SANTA (SANT Associated) 108.59 0.7347 97 Mapoly0074s0001 [PF03810] Importin-beta N-terminal domain; [PF08767] CRM1 C terminal; [KOG2020] Nuclear transport receptor CRM1/MSN5 (importin beta superfamily); [PTHR11223] EXPORTIN 1/5; [GO:0006886] intracellular protein transport; [PTHR11223:SF2] EXPORTIN 1 (CHROMOSOME REGION MAINTENANCE PROTEIN 1); [K14290] exportin-1; [GO:0008536] Ran GTPase binding; [PF08389] Exportin 1-like protein 109.22 0.6725 98 Mapoly0020s0107 [KOG4626] O-linked N-acetylglucosamine transferase OGT; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13432] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat; [PF13844] Glycosyl transferase family 41; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR 109.36 0.7151 99 Mapoly0004s0300 [GO:0005524] ATP binding; [PTHR11909:SF7] CELL DIVISION CONTROL PROTEIN 7; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K02214] cell division control protein 7 [EC:2.7.11.1]; [KOG1167] Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination; [GO:0006468] protein phosphorylation; [PTHR11909] CASEIN KINASE-RELATED 109.82 0.7397 100 Mapoly0034s0031 [GO:0007094] mitotic spindle assembly checkpoint; [K06638] mitotic spindle assembly checkpoint protein MAD1; [KOG4593] Mitotic checkpoint protein MAD1; [PTHR23168] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 (MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1); [PF05557] Mitotic checkpoint protein; [PTHR23168:SF0] SUBFAMILY NOT NAMED 109.98 0.7371 101 Mapoly0045s0049 - 109.98 0.6877 102 Mapoly0019s0176 [KOG0320] Predicted E3 ubiquitin ligase; [PF13920] Zinc finger, C3HC4 type (RING finger); [PTHR12183] UNCHARACTERIZED RING ZINC FINGER-CONTAINING PROTEIN 111.28 0.6855 103 Mapoly0035s0108 [GO:0005524] ATP binding; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23074] AAA ATPASE; [KOG0740] AAA+-type ATPase; [PF09336] Vps4 C terminal oligomerisation domain; [PTHR23074:SF17] FIDGETIN LIKE-1 111.28 0.7176 104 Mapoly0048s0100 [PTHR18937:SF8] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC3; [GO:0005524] ATP binding; [KOG0964] Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3); [GO:0008280] cohesin core heterodimer; [GO:0005515] protein binding; [GO:0003682] chromatin binding; [GO:0007064] mitotic sister chromatid cohesion; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain; [K06669] structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) 111.87 0.7236 105 Mapoly0091s0060 - 112.25 0.6829 106 Mapoly0098s0032 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [PF11721] Di-glucose binding within endoplasmic reticulum; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 113.29 0.7384 107 Mapoly0052s0095 [GO:0005643] nuclear pore; [PTHR31344:SF0] SUBFAMILY NOT NAMED; [K14310] nuclear pore complex protein Nup205; [PF11894] Protein of unknown function (DUF3414); [PTHR31344] FAMILY NOT NAMED; [KOG1835] Uncharacterized conserved protein 113.49 0.7099 108 Mapoly0143s0029 - 114.45 0.6702 109 Mapoly0148s0003 [KOG1493] Anaphase-promoting complex (APC), subunit 11; [PTHR14155] RING FINGER DOMAIN-CONTAINING; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding 114.46 0.6535 110 Mapoly0026s0020 [KOG2253] U1 snRNP complex, subunit SNU71 and related PWI-motif proteins 114.63 0.7198 111 Mapoly0091s0056 [PF05918] Apoptosis inhibitory protein 5 (API5); [KOG2213] Apoptosis inhibitor 5/fibroblast growth factor 2-interacting factor 2, and related proteins; [PTHR12758] APOPTOSIS INHIBITOR 5-RELATED 115.18 0.7173 112 Mapoly0118s0005 [GO:0008233] peptidase activity; [3.4.22.49] Separase.; [K02365] separase [EC:3.4.22.49]; [GO:0005634] nucleus; [PF03568] Peptidase family C50; [GO:0006508] proteolysis; [PTHR12792] EXTRA SPINDLE POLES 1-RELATED 115.33 0.7289 113 Mapoly0068s0104 [PF04802] Component of IIS longevity pathway SMK-1; [KOG2175] Protein predicted to be involved in carbohydrate metabolism; [PTHR23318] ATP SYNTHASE GAMMA-RELATED 115.46 0.7353 114 Mapoly0045s0061 [KOG1081] Transcription factor NSD1 and related SET domain proteins; [GO:0005515] protein binding; [PF00856] SET domain; [PTHR22884] SET DOMAIN PROTEINS 115.65 0.7220 115 Mapoly0001s0044 [PTHR31110] FAMILY NOT NAMED 115.96 0.7261 116 Mapoly0029s0052 [GO:0006357] regulation of transcription from RNA polymerase II promoter; [PTHR12950] FAMILY NOT NAMED; [GO:0001104] RNA polymerase II transcription cofactor activity; [GO:0016592] mediator complex; [PF06333] Mediator complex subunit 13 C-terminal 116.20 0.7226 117 Mapoly0117s0005 [K13109] IK cytokine; [PTHR12765] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [KOG2498] IK cytokine down-regulator of HLA class II; [PF07807] RED-like protein C-terminal region; [PTHR12765:SF5] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [GO:0005634] nucleus; [PF07808] RED-like protein N-terminal region 116.83 0.7135 118 Mapoly0148s0032 [PF01480] PWI domain; [PTHR18806:SF4] SUBFAMILY NOT NAMED; [GO:0006397] mRNA processing; [PTHR18806] RBM25 PROTEIN; [GO:0003676] nucleic acid binding; [K12822] RNA-binding protein 25; [KOG2253] U1 snRNP complex, subunit SNU71 and related PWI-motif proteins; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 117.03 0.7241 119 Mapoly0005s0174 [GO:0005524] ATP binding; [KOG0933] Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E); [GO:0007076] mitotic chromosome condensation; [GO:0005515] protein binding; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0000796] condensin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PTHR18937:SF9] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC2; [K06674] structural maintenance of chromosome 2; [PF06470] SMC proteins Flexible Hinge Domain 117.46 0.7377 120 Mapoly0013s0183 [KOG2739] Leucine-rich acidic nuclear protein; [PF14580] Leucine-rich repeat; [PTHR11375] ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 118.49 0.6979 121 Mapoly0014s0073 [KOG1663] O-methyltransferase; [GO:0008171] O-methyltransferase activity; [PTHR10509] O-METHYLTRANSFERASE-RELATED; [PF01596] O-methyltransferase 120.08 0.6749 122 Mapoly0004s0202 - 120.66 0.7263 123 Mapoly0009s0110 [PF03468] XS domain; [GO:0031047] gene silencing by RNA; [PF13920] Zinc finger, C3HC4 type (RING finger) 123.21 0.6369 124 Mapoly0002s0028 [PF00630] Filamin/ABP280 repeat; [GO:0003676] nucleic acid binding; [KOG0146] RNA-binding protein ETR-3 (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 124.30 0.7153 125 Mapoly0063s0093 [PF07714] Protein tyrosine kinase; [KOG0192] Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs; [PTHR23257] SERINE-THREONINE PROTEIN KINASE; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [GO:0005543] phospholipid binding; [PF07651] ANTH domain 124.71 0.6720 126 Mapoly0105s0028 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 126.42 0.7045 127 Mapoly0130s0046 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF14493] Helix-turn-helix domain; [PF09382] RQC domain; [K10900] werner syndrome ATP-dependent helicase [EC:3.6.4.12]; [KOG0353] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 127.94 0.7189 128 Mapoly0038s0101 [K12837] splicing factor U2AF 65 kDa subunit; [PTHR23139] RNA-BINDING PROTEIN; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG0120] Splicing factor U2AF, large subunit (RRM superfamily); [GO:0003676] nucleic acid binding; [PTHR23139:SF9] SPLICING FACTOR U2AF LARGE SUBUNIT; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 128.15 0.7157 129 Mapoly0056s0030 [KOG1040] Polyadenylation factor I complex, subunit, Yth1 (CPSF subunit); [PTHR12357] YTH (YT521-B HOMOLOGY) DOMAIN-CONTAINING; [PF04146] YT521-B-like domain; [PTHR12357:SF3] SPLICING FACTOR YT521-B 130.32 0.6798 130 Mapoly0125s0020 [PF06972] Protein of unknown function (DUF1296); [PTHR12758] APOPTOSIS INHIBITOR 5-RELATED; [PTHR12758:SF13] APOPTOSIS INHIBITOR 5-RELATED 132.21 0.6670 131 Mapoly0009s0028 [PTHR22812] CHROMOBOX PROTEIN; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain 132.35 0.7080 132 Mapoly0078s0012 [GO:0006396] RNA processing; [PTHR11061] RNA M5U METHYLTRANSFERASE FAMILY; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0008173] RNA methyltransferase activity; [PF05958] tRNA (Uracil-5-)-methyltransferase; [GO:0046872] metal ion binding; [KOG2187] tRNA uracil-5-methyltransferase and related tRNA-modifying enzymes 132.45 0.7019 133 Mapoly0064s0049 [PTHR19321:SF5] PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED; [GO:0000226] microtubule cytoskeleton organization; [GO:0000910] cytokinesis; [GO:0008017] microtubule binding; [PF03999] Microtubule associated protein (MAP65/ASE1 family); [KOG4302] Microtubule-associated protein essential for anaphase spindle elongation; [PTHR19321] PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED 133.70 0.6835 134 Mapoly0001s0208 [PTHR31431] FAMILY NOT NAMED; [KOG4833] Uncharacterized conserved protein; [K14311] nuclear pore complex protein Nup188; [PF10487] Nucleoporin subcomplex protein binding to Pom34 134.11 0.7117 135 Mapoly0074s0062 [PF00011] Hsp20/alpha crystallin family 138.14 0.5409 136 Mapoly0081s0071 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [PF00628] PHD-finger; [GO:0005515] protein binding; [PF12738] twin BRCT domain; [GO:0046872] metal ion binding 138.92 0.7167 137 Mapoly0053s0080 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PF12230] Pre-mRNA splicing factor PRP21 like protein; [GO:0005515] protein binding; [PTHR15316:SF1] SPLICEOSOME ASSOCIATED PROTEIN 114; [PF00240] Ubiquitin family; [K12825] splicing factor 3A subunit 1; [PTHR15316] SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED; [PF01805] Surp module; [KOG0007] Splicing factor 3a, subunit 1 140.72 0.7042 138 Mapoly0034s0119 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 140.73 0.7230 139 Mapoly0099s0053 [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 141.54 0.7029 140 Mapoly0074s0003 [GO:0003677] DNA binding; [PF12254] DNA polymerase alpha subunit p180 N terminal; [GO:0006260] DNA replication; [GO:0001882] nucleoside binding; [K02320] DNA polymerase alpha subunit A [EC:2.7.7.7]; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0006270] DNA replication initiation; [PF08996] DNA Polymerase alpha zinc finger; [KOG0970] DNA polymerase alpha, catalytic subunit; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT 144.35 0.6986 141 Mapoly0050s0019 [PF08642] Histone deacetylation protein Rxt3; [KOG4843] Uncharacterized conserved protein 146.12 0.6838 142 Mapoly0005s0048 [K14328] regulator of nonsense transcripts 3; [PTHR13112:SF0] SUBFAMILY NOT NAMED; [PTHR13112] UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN; [PF03467] Smg-4/UPF3 family 147.52 0.6494 143 Mapoly0051s0078 [GO:0006355] regulation of transcription, DNA-dependent; [KOG0266] WD40 repeat-containing protein; [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [PF00400] WD domain, G-beta repeat 149.44 0.6895 144 Mapoly0015s0183 [GO:0000922] spindle pole; [PF04130] Spc97 / Spc98 family; [GO:0000226] microtubule cytoskeleton organization; [GO:0005815] microtubule organizing center; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN 149.99 0.6422 145 Mapoly0122s0062 [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 150.08 0.7161 146 Mapoly0051s0067 [PF00651] BTB/POZ domain; [PTHR24411] FAMILY NOT NAMED; [PF00917] MATH domain; [GO:0005515] protein binding; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 151.30 0.6648 147 Mapoly0032s0119 [GO:0007076] mitotic chromosome condensation; [K06678] condensin complex subunit 3; [GO:0000796] condensin complex; [PTHR14418] CONDENSIN COMPLEX SUBUNIT 3-RELATED; [PF12719] Nuclear condensing complex subunits, C-term domain 152.71 0.7132 148 Mapoly0009s0056 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PF08311] Mad3/BUB1 homology region 1; [K02178] checkpoint serine/threonine-protein kinase [EC:2.7.11.1]; [KOG1166] Mitotic checkpoint serine/threonine protein kinase; [PTHR14030] MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 153.36 0.7064 149 Mapoly0107s0024 [GO:0005524] ATP binding; [GO:0046982] protein heterodimerization activity; [KOG0018] Structural maintenance of chromosome protein 1 (sister chromatid cohesion complex Cohesin, subunit SMC1); [GO:0005515] protein binding; [GO:0003682] chromatin binding; [PTHR18937:SF12] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC1; [GO:0007064] mitotic sister chromatid cohesion; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0008278] cohesin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain; [K06636] structural maintenance of chromosome 1 154.21 0.6965 150 Mapoly0005s0005 [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00856] SET domain; [PTHR22884] SET DOMAIN PROTEINS 154.82 0.6721 151 Mapoly0004s0250 [GO:0005643] nuclear pore; [PF07817] GLE1-like protein; [GO:0016973] poly(A)+ mRNA export from nucleus; [KOG2412] Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor; [PTHR12960:SF0] SUBFAMILY NOT NAMED; [PTHR12960] GLE-1-RELATED 155.00 0.7005 152 Mapoly0005s0045 [PF15628] RRM in Demeter; [PTHR10359] A/G-SPECIFIC ADENINE GLYCOSYLASE/ENDONUCLEASE III 157.35 0.7009 153 Mapoly0015s0045 [KOG0533] RRM motif-containing protein; [PTHR19965] RNA AND EXPORT FACTOR BINDING PROTEIN; [K12881] THO complex subunit 4; [PF13865] C-terminal duplication domain of Friend of PRMT1; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 157.84 0.6880 154 Mapoly0105s0035 [PTHR12341] 5'-3' EXORIBONUCLEASE; [PF03159] XRN 5'-3' exonuclease N-terminus; [K12619] 5'-3' exoribonuclease 2 [EC:3.1.13.-]; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [3.1.13.-] Exoribonucleases producing 5'-phosphomonoesters.; [GO:0003676] nucleic acid binding; [GO:0004527] exonuclease activity 157.87 0.7037 155 Mapoly0010s0010 [GO:0005643] nuclear pore; [PF13874] Nucleoporin complex subunit 54; [PTHR13000] NUCLEOPORIN P54; [KOG3091] Nuclear pore complex, p54 component (sc Nup57) 158.13 0.7001 156 Mapoly0006s0231 [KOG0123] Polyadenylate-binding protein (RRM superfamily); [PTHR24011] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF07744] SPOC domain; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 158.42 0.7183 157 Mapoly0068s0092 [GO:0003723] RNA binding; [PF00013] KH domain 159.08 0.6859 158 Mapoly0010s0094 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [PF00454] Phosphatidylinositol 3- and 4-kinase; [KOG0889] Histone acetyltransferase SAGA, TRRAP/TRA1 component, PI-3 kinase superfamily; [PTHR11139:SF1] ATM-RELATED; [K08874] transformation/transcription domain-associated protein; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED 160.06 0.6993 159 Mapoly0002s0070 [GO:0008270] zinc ion binding; [PTHR23336:SF2] SUBFAMILY NOT NAMED; [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PTHR23336] ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3.; [PF07496] CW-type Zinc Finger 160.60 0.6743 160 Mapoly0004s0169 [GO:0003677] DNA binding; [GO:0006338] chromatin remodeling; [GO:0005524] ATP binding; [PF09110] HAND; [K11654] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]; [GO:0043044] ATP-dependent chromatin remodeling; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [GO:0005634] nucleus; [PTHR10799:SF73] ISWI CHROMATIN-REMODELING COMPLEX ATPASE ISW1; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [KOG0385] Chromatin remodeling complex WSTF-ISWI, small subunit; [GO:0003676] nucleic acid binding; [GO:0031491] nucleosome binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [PF09111] SLIDE 160.92 0.7130 161 Mapoly0098s0043 [PF12717] non-SMC mitotic condensation complex subunit 1; [GO:0007076] mitotic chromosome condensation; [K11491] condensin-2 complex subunit D3; [PTHR14222:SF1] CONDENSIN; [PTHR14222] CONDENSIN 161.21 0.7081 162 Mapoly0042s0023 [GO:0005524] ATP binding; [2.7.12.1] Dual-specificity kinase.; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [K08866] serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]; [PTHR22974] MIXED LINEAGE PROTEIN KINASE 161.85 0.7102 163 Mapoly0099s0003 [GO:0000922] spindle pole; [PF04130] Spc97 / Spc98 family; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN 162.46 0.6879 164 Mapoly0158s0032 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [K10728] topoisomerase (DNA) II binding protein 1; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 162.81 0.6816 165 Mapoly0042s0049 - 164.37 0.7086 166 Mapoly0042s0047 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF65] DNA REPAIR AND RECOMBINATION PROTEIN RAD26-RELATED 166.95 0.6997 167 Mapoly0028s0110 [GO:0005524] ATP binding; [PTHR23069] TAT-BINDING HOMOLOG 7; [PTHR23069:SF0] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [PF00439] Bromodomain; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0732] AAA+-type ATPase containing the bromodomain 167.42 0.6972 168 Mapoly0001s0525 [K14408] cleavage stimulation factor subunit 3; [GO:0006397] mRNA processing; [GO:0005634] nucleus; [KOG1914] mRNA cleavage and polyadenylation factor I complex, subunit RNA14; [PTHR19980] RNA CLEAVAGE STIMULATION FACTOR; [PF05843] Suppressor of forked protein (Suf) 167.58 0.7074 169 Mapoly0041s0101 [GO:0005524] ATP binding; [K02603] origin recognition complex subunit 1; [PF01426] BAH domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [GO:0003682] chromatin binding; [PTHR10763:SF6] ORIGIN RECOGNITION COMPLEX SUBUNIT 1; [KOG1514] Origin recognition complex, subunit 1, and related proteins; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR10763] CELL DIVISION CONTROL PROTEIN 6-RELATED 167.77 0.6682 170 Mapoly0010s0152 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PTHR13561:SF5] DNA REPLICATION REGULATOR DPB11; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 167.81 0.7021 171 Mapoly0147s0014 [PTHR14790] FAMILY NOT NAMED; [PF08585] Domain of unknown function (DUF1767) 168.04 0.6922 172 Mapoly0024s0107 [PF07719] Tetratricopeptide repeat; [GO:0005515] protein binding; [PF13414] TPR repeat; [K03350] anaphase-promoting complex subunit 3; [KOG1126] DNA-binding cell division cycle control protein; [PF13181] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat; [PTHR12558] CELL DIVISION CYCLE 16,23,27; [PTHR12558:SF11] CELL DIVISION CYCLE 27; [PF12895] Anaphase-promoting complex, cyclosome, subunit 3 169.83 0.6804 173 Mapoly0021s0043 - 170.46 0.6877 174 Mapoly0060s0055 [PF07748] Glycosyl hydrolases family 38 C-terminal domain; [GO:0015923] mannosidase activity; [KOG1959] Glycosyl hydrolase, family 38 - alpha-mannosidase; [PTHR11607] ALPHA-MANNOSIDASE; [GO:0004559] alpha-mannosidase activity; [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [GO:0006013] mannose metabolic process; [PF09261] Alpha mannosidase, middle domain; [GO:0005975] carbohydrate metabolic process; [GO:0008270] zinc ion binding; [PF01074] Glycosyl hydrolases family 38 N-terminal domain 170.92 0.6523 175 Mapoly0001s0369 [K12879] THO complex subunit 2; [PF11262] Transcription factor/nuclear export subunit protein 2; [PTHR21597] THO2 PROTEIN; [PF11732] Transcription- and export-related complex subunit; [PTHR21597:SF0] SUBFAMILY NOT NAMED; [KOG1874] KEKE-like motif-containing transcription regulator (Rlr1)/suppressor of sin4 171.71 0.7075 176 Mapoly0033s0111 [PTHR13587] FAMILY NOT NAMED; [K13140] integrator complex subunit 3; [PF10189] Conserved protein (DUF2356); [KOG4262] Uncharacterized conserved protein 172.18 0.7053 177 Mapoly0010s0062 [KOG2250] Glutamate/leucine/phenylalanine/valine dehydrogenases; [GO:0055114] oxidation-reduction process; [PTHR11606] GLUTAMATE DEHYDROGENASE; [GO:0016491] oxidoreductase activity; [PF00208] Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; [K00262] glutamate dehydrogenase (NADP+) [EC:1.4.1.4]; [GO:0006520] cellular amino acid metabolic process; [PTHR11606:SF4] SUBFAMILY NOT NAMED; [1.4.1.4] Glutamate dehydrogenase (NADP(+)).; [PF02812] Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 172.90 0.6955 178 Mapoly0053s0106 - 173.67 0.7018 179 Mapoly0001s0355 [GO:0016020] membrane; [GO:0004222] metalloendopeptidase activity; [PF01457] Leishmanolysin; [PF07974] EGF-like domain; [KOG2556] Leishmanolysin-like peptidase (Peptidase M8 family); [3.4.24.36] Leishmanolysin.; [GO:0007155] cell adhesion; [GO:0006508] proteolysis; [K01404] leishmanolysin [EC:3.4.24.36]; [PTHR10942] LEISHMANOLYSIN-LIKE PEPTIDASE 174.12 0.6820 180 Mapoly0010s0132 [KOG4825] Component of synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine-binding glycoprotein (43kDa); [PF02151] UvrB/uvrC motif; [GO:0005515] protein binding; [PTHR13371] GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN; [PTHR13371:SF0] SUBFAMILY NOT NAMED 175.00 0.6377 181 Mapoly0096s0011 [PTHR12436] 80 KDA MCM3-ASSOCIATED PROTEIN; [PF03399] SAC3/GANP/Nin1/mts3/eIF-3 p25 family 175.08 0.6936 182 Mapoly0020s0135 [PF03941] Inner centromere protein, ARK binding region; [PTHR13142:SF1] INCENP; [KOG1295] Nonsense-mediated decay protein Upf3; [PTHR13142] INNER CENTROMERE PROTEIN 175.44 0.6997 183 Mapoly0029s0108 [PTHR10161] TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5; [K14379] tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]; [PF00149] Calcineurin-like phosphoesterase; [GO:0016787] hydrolase activity; [KOG2679] Purple (tartrate-resistant) acid phosphatase; [3.1.3.2] Acid phosphatase. 175.54 0.6973 184 Mapoly0016s0083 [PF12214] Cell cycle regulated microtubule associated protein; [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [PTHR14326:SF9] TARGETING PROTEIN FOR XKLP2; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2) 175.93 0.6963 185 Mapoly0151s0018 [PF00917] MATH domain; [GO:0005515] protein binding; [PTHR24006] FAMILY NOT NAMED 176.36 0.7126 186 Mapoly0132s0046 [PF00855] PWWP domain; [PTHR12550] HEPATOMA-DERIVED GROWTH FACTOR-RELATED; [PTHR12550:SF5] UNCHARACTERIZED 176.95 0.6763 187 Mapoly0179s0020 [KOG1293] Proteins containing armadillo/beta-catenin-like repeat; [PTHR15651:SF7] SUBFAMILY NOT NAMED; [PF00514] Armadillo/beta-catenin-like repeat; [GO:0005515] protein binding; [PTHR15651] FAMILY NOT NAMED 179.83 0.6194 188 Mapoly0014s0220 [GO:0006355] regulation of transcription, DNA-dependent; [K11308] histone acetyltransferase MYST1 [EC:2.3.1.48]; [PF11717] RNA binding activity-knot of a chromodomain; [PTHR10615] HISTONE ACETYLTRANSFERASE; [GO:0016747] transferase activity, transferring acyl groups other than amino-acyl groups; [GO:0005634] nucleus; [PF01853] MOZ/SAS family; [2.3.1.48] Histone acetyltransferase.; [KOG2747] Histone acetyltransferase (MYST family) 180.65 0.6562 189 Mapoly0031s0066 [PTHR12087:SF0] SUBFAMILY NOT NAMED; [KOG2228] Origin recognition complex, subunit 4; [PF13191] AAA ATPase domain; [PF14629] Origin recognition complex (ORC) subunit 4 C-terminus; [PTHR12087] ORIGIN RECOGNITION COMPLEX SUBUNIT 4; [K02606] origin recognition complex subunit 4 180.70 0.5690 190 Mapoly0137s0008 [PF06278] Protein of unknown function (DUF1032); [PTHR14324] FAMILY NOT NAMED; [PTHR14324:SF3] SUBFAMILY NOT NAMED; [K11490] condensin-2 complex subunit H2; [KOG2359] Uncharacterized conserved protein 183.00 0.6867 191 Mapoly0021s0012 [PF00443] Ubiquitin carboxyl-terminal hydrolase; [GO:0006511] ubiquitin-dependent protein catabolic process; [PF02810] SEC-C motif; [KOG1865] Ubiquitin carboxyl-terminal hydrolase; [PTHR24006] FAMILY NOT NAMED; [PF01753] MYND finger 183.07 0.6671 192 Mapoly0012s0166 [PF09405] CASC3/Barentsz eIF4AIII binding; [PTHR22814:SF47] HEAVY-METAL-ASSOCIATED DOMAIN-CONTAINING PROTEIN; [PTHR22814] COPPER TRANSPORT PROTEIN ATOX1-RELATED 184.47 0.6770 193 Mapoly0029s0003 [KOG1824] TATA-binding protein-interacting protein; [PTHR12696] TIP120; [PF08623] TATA-binding protein interacting (TIP20); [PF13646] HEAT repeats 185.32 0.6931 194 Mapoly0189s0011 [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain 185.50 0.6930 195 Mapoly0024s0112 [GO:0005643] nuclear pore; [KOG1964] Nuclear pore complex, rNup107 component (sc Nup84); [PTHR13003] NUP107-RELATED; [GO:0006810] transport; [PF04121] Nuclear pore protein 84 / 107; [K14301] nuclear pore complex protein Nup107 187.08 0.6977 196 Mapoly0022s0167 [PF12717] non-SMC mitotic condensation complex subunit 1; [PF12922] non-SMC mitotic condensation complex subunit 1, N-term; [GO:0007076] mitotic chromosome condensation; [PTHR14222] CONDENSIN; [KOG0414] Chromosome condensation complex Condensin, subunit D2; [K06677] condensin complex subunit 1 187.44 0.6958 197 Mapoly0063s0094 - 187.73 0.6535 198 Mapoly0061s0132 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity; [KOG0246] Kinesin-like protein; [K10393] kinesin family member 2/24 187.83 0.6464 199 Mapoly0042s0059 [PTHR16426] UBINUCLEIN/YEMANUCLEIN; [PF08729] HPC2 and ubinuclein domain 187.88 0.6913 200 Mapoly0084s0055 [GO:0005524] ATP binding; [KOG0744] AAA+-type ATPase; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23077] AAA-FAMILY ATPASE 190.31 0.6826