| 1 |
Mapoly0007s0066
| [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PTHR19306:SF1] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5 SMC5; [KOG0979] Structural maintenance of chromosome protein SMC5/Spr18, SMC superfamily; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0000724] double-strand break repair via homologous recombination | 1.00 | 0.8568 |
| 2 |
Mapoly0005s0093
| [KOG1883] Cofactor required for Sp1 transcriptional activation, subunit 3; [PF11573] Mediator complex subunit 23; [PTHR12691] FAMILY NOT NAMED | 2.83 | 0.8315 |
| 3 |
Mapoly0125s0028
| [GO:0000166] nucleotide binding; [PF00702] haloacid dehalogenase-like hydrolase; [KOG0205] Plasma membrane H+-transporting ATPase; [PTHR24093] FAMILY NOT NAMED; [PF00690] Cation transporter/ATPase, N-terminus; [GO:0046872] metal ion binding; [PF00122] E1-E2 ATPase | 2.83 | 0.8553 |
| 4 |
Mapoly0005s0045
| [PF15628] RRM in Demeter; [PTHR10359] A/G-SPECIFIC ADENINE GLYCOSYLASE/ENDONUCLEASE III | 5.29 | 0.8281 |
| 5 |
Mapoly0053s0080
| [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PF12230] Pre-mRNA splicing factor PRP21 like protein; [GO:0005515] protein binding; [PTHR15316:SF1] SPLICEOSOME ASSOCIATED PROTEIN 114; [PF00240] Ubiquitin family; [K12825] splicing factor 3A subunit 1; [PTHR15316] SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED; [PF01805] Surp module; [KOG0007] Splicing factor 3a, subunit 1 | 6.63 | 0.8218 |
| 6 |
Mapoly0001s0378
| [PTHR32086] FAMILY NOT NAMED; [K10891] fanconi anemia group D2 protein; [GO:0006281] DNA repair; [KOG4712] Uncharacterized conserved protein; [PF14631] Fanconi anaemia protein FancD2 nuclease | 7.07 | 0.8301 |
| 7 |
Mapoly0004s0286
| [PTHR12663:SF0] SUBFAMILY NOT NAMED; [K11267] sister chromatid cohesion protein PDS5; [PTHR12663] ANDROGEN INDUCED INHIBITOR OF PROLIFERATION (AS3) / PDS5-RELATED; [KOG1525] Sister chromatid cohesion complex Cohesin, subunit PDS5 | 9.33 | 0.8405 |
| 8 |
Mapoly0135s0035
| [GO:0003676] nucleic acid binding; [PF02037] SAP domain | 9.49 | 0.8299 |
| 9 |
Mapoly0111s0003
| - | 9.75 | 0.8101 |
| 10 |
Mapoly0092s0032
| [PTHR22597] POLYCOMB GROUP PROTEIN; [PTHR22597:SF0] SUBFAMILY NOT NAMED; [PF09733] VEFS-Box of polycomb protein | 12.33 | 0.8274 |
| 11 |
Mapoly0013s0109
| [PF00514] Armadillo/beta-catenin-like repeat; [PF00651] BTB/POZ domain; [GO:0005515] protein binding; [KOG0166] Karyopherin (importin) alpha; [PTHR23315] BETA CATENIN-RELATED ARMADILLO REPEAT-CONTAINING | 15.20 | 0.8073 |
| 12 |
Mapoly0158s0032
| [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [K10728] topoisomerase (DNA) II binding protein 1; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain | 15.68 | 0.7899 |
| 13 |
Mapoly0070s0095
| [PTHR23215] ZINC FINGER PROTEIN 207; [KOG2893] Zn finger protein | 15.72 | 0.8208 |
| 14 |
Mapoly0010s0094
| [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [PF00454] Phosphatidylinositol 3- and 4-kinase; [KOG0889] Histone acetyltransferase SAGA, TRRAP/TRA1 component, PI-3 kinase superfamily; [PTHR11139:SF1] ATM-RELATED; [K08874] transformation/transcription domain-associated protein; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED | 16.43 | 0.8263 |
| 15 |
Mapoly0058s0108
| [GO:0003677] DNA binding; [KOG0214] RNA polymerase II, second largest subunit; [PF04567] RNA polymerase Rpb2, domain 5; [PF04565] RNA polymerase Rpb2, domain 3; [PTHR20856] DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2; [PF00562] RNA polymerase Rpb2, domain 6; [PF04566] RNA polymerase Rpb2, domain 4; [GO:0032549] ribonucleoside binding; [PF04561] RNA polymerase Rpb2, domain 2; [GO:0006351] transcription, DNA-dependent; [GO:0003899] DNA-directed RNA polymerase activity; [PF04560] RNA polymerase Rpb2, domain 7; [PF04563] RNA polymerase beta subunit | 16.91 | 0.7992 |
| 16 |
Mapoly0107s0024
| [GO:0005524] ATP binding; [GO:0046982] protein heterodimerization activity; [KOG0018] Structural maintenance of chromosome protein 1 (sister chromatid cohesion complex Cohesin, subunit SMC1); [GO:0005515] protein binding; [GO:0003682] chromatin binding; [PTHR18937:SF12] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC1; [GO:0007064] mitotic sister chromatid cohesion; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0008278] cohesin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain; [K06636] structural maintenance of chromosome 1 | 17.00 | 0.8128 |
| 17 |
Mapoly0087s0021
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [KOG0969] DNA polymerase delta, catalytic subunit; [PTHR10322:SF11] DNA POLYMERASE DELTA CATALYTIC SUBUNIT; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [K02327] DNA polymerase delta subunit 1 [EC:2.7.7.7]; [PF14260] C4-type zinc-finger of DNA polymerase delta; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT | 18.65 | 0.7963 |
| 18 |
Mapoly0005s0067
| [PTHR15242:SF0] SUBFAMILY NOT NAMED; [PTHR15242] SPLICING FACTOR, ARGININE/SERINE-RICH 2,RNAP C-TERM INTERACTING PROTEIN; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding | 18.97 | 0.8249 |
| 19 |
Mapoly0063s0041
| [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR23340] ARGININE/SERINE RICH SPLICING FACTOR SF4/14; [PF01585] G-patch domain; [GO:0003676] nucleic acid binding; [PF01805] Surp module | 19.44 | 0.7983 |
| 20 |
Mapoly0029s0099
| [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PTHR23336:SF7] SUBFAMILY NOT NAMED; [KOG1845] MORC family ATPases; [PTHR23336] ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3. | 20.00 | 0.7997 |
| 21 |
Mapoly0041s0148
| [PF01426] BAH domain; [GO:0003682] chromatin binding; [PTHR12505] PHD FINGER TRANSCRIPTION FACTOR | 20.20 | 0.7935 |
| 22 |
Mapoly0045s0096
| [K08775] breast cancer 2 susceptibility protein; [PTHR11289] BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2; [GO:0003697] single-stranded DNA binding; [PF09169] BRCA2, helical; [PTHR11289:SF0] SUBFAMILY NOT NAMED; [GO:0006281] DNA repair; [PF09103] BRCA2, oligonucleotide/oligosaccharide-binding, domain 1; [GO:0000724] double-strand break repair via homologous recombination; [GO:0006310] DNA recombination | 20.49 | 0.7477 |
| 23 |
Mapoly0052s0086
| [PF05641] Agenet domain; [PTHR31917] FAMILY NOT NAMED | 20.49 | 0.8216 |
| 24 |
Mapoly0002s0093
| [PTHR24012] FAMILY NOT NAMED; [KOG4205] RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1; [K12741] heterogeneous nuclear ribonucleoprotein A1/A3; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 21.66 | 0.7635 |
| 25 |
Mapoly0113s0037
| [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [KOG2577] Transcription factor E2F/dimerization partner (TDP); [PTHR12081] TRANSCRIPTION FACTOR E2F | 22.52 | 0.7904 |
| 26 |
Mapoly0104s0042
| [PTHR22846:SF2] TRANSDUCIN BETA-LIKE 1; [GO:0005515] protein binding; [PTHR22846] WD40 REPEAT PROTEIN; [KOG0273] Beta-transducin family (WD-40 repeat) protein; [PF08513] LisH; [PF00400] WD domain, G-beta repeat | 22.63 | 0.8130 |
| 27 |
Mapoly0001s0472
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED | 25.10 | 0.8172 |
| 28 |
Mapoly0104s0019
| [KOG2242] Scaffold/matrix specific factor hnRNP-U/SAF-A, contains SPRY domain; [PTHR12381:SF13] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [PF13671] AAA domain; [PF00622] SPRY domain; [PTHR12381] RIBONUCLEOPROTEIN | 25.26 | 0.8034 |
| 29 |
Mapoly0103s0053
| [GO:0008168] methyltransferase activity; [PTHR23068:SF3] gb def: Hypothetical protein T15N1_120; [PTHR23068] DNA (CYTOSINE-5-)-METHYLTRANSFERASE 3-RELATED; [PF00145] C-5 cytosine-specific DNA methylase | 26.46 | 0.7603 |
| 30 |
Mapoly0006s0290
| [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR10670:SF0] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A; [GO:0000166] nucleotide binding; [GO:0008270] zinc ion binding; [2.7.7.7] DNA-directed DNA polymerase.; [KOG1798] DNA polymerase epsilon, catalytic subunit A; [PF08490] Domain of unknown function (DUF1744); [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF00136] DNA polymerase family B; [GO:0008622] epsilon DNA polymerase complex; [K02324] DNA polymerase epsilon subunit 1 [EC:2.7.7.7]; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10670] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A | 26.72 | 0.8204 |
| 31 |
Mapoly0080s0034
| [2.1.1.43] Histone-lysine N-methyltransferase.; [KOG1082] Histone H3 (Lys9) methyltransferase SUV39H1/Clr4, required for transcriptional silencing; [K11419] histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43]; [PF05033] Pre-SET motif; [GO:0005515] protein binding; [PF00856] SET domain; [GO:0008270] zinc ion binding; [GO:0018024] histone-lysine N-methyltransferase activity; [PTHR22884] SET DOMAIN PROTEINS; [GO:0005634] nucleus; [GO:0034968] histone lysine methylation; [PF13771] PHD-like zinc-binding domain | 27.75 | 0.7932 |
| 32 |
Mapoly0060s0055
| [PF07748] Glycosyl hydrolases family 38 C-terminal domain; [GO:0015923] mannosidase activity; [KOG1959] Glycosyl hydrolase, family 38 - alpha-mannosidase; [PTHR11607] ALPHA-MANNOSIDASE; [GO:0004559] alpha-mannosidase activity; [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [GO:0006013] mannose metabolic process; [PF09261] Alpha mannosidase, middle domain; [GO:0005975] carbohydrate metabolic process; [GO:0008270] zinc ion binding; [PF01074] Glycosyl hydrolases family 38 N-terminal domain | 28.46 | 0.7504 |
| 33 |
Mapoly0048s0100
| [PTHR18937:SF8] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC3; [GO:0005524] ATP binding; [KOG0964] Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3); [GO:0008280] cohesin core heterodimer; [GO:0005515] protein binding; [GO:0003682] chromatin binding; [GO:0007064] mitotic sister chromatid cohesion; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain; [K06669] structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) | 29.98 | 0.7953 |
| 34 |
Mapoly0027s0185
| [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF39] CDC2-RELATED PROTEIN KINASE; [KOG0600] Cdc2-related protein kinase; [K08819] Cdc2-related kinase, arginine/serine-rich [EC:2.7.11.22]; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE | 31.46 | 0.7864 |
| 35 |
Mapoly0001s0473
| - | 31.62 | 0.8077 |
| 36 |
Mapoly0034s0011
| [PF09133] SANTA (SANT Associated) | 31.81 | 0.8002 |
| 37 |
Mapoly0027s0186
| [GO:0005524] ATP binding; [K10866] DNA repair protein RAD50 [EC:3.6.-.-]; [PF13476] AAA domain; [GO:0008270] zinc ion binding; [PF04423] Rad50 zinc hook motif; [3.6.-.-] Acting on acid anhydrides.; [GO:0006281] DNA repair; [KOG0962] DNA repair protein RAD50, ABC-type ATPase/SMC superfamily; [PTHR18867:SF12] SUBFAMILY NOT NAMED; [PTHR18867] RAD50; [GO:0004518] nuclease activity; [GO:0030870] Mre11 complex; [PF13558] Putative exonuclease SbcCD, C subunit | 33.94 | 0.7999 |
| 38 |
Mapoly0099s0053
| [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding | 34.06 | 0.7903 |
| 39 |
Mapoly0067s0005
| [PTHR24012] FAMILY NOT NAMED; [PTHR24012:SF39] SUBFAMILY NOT NAMED; [KOG0147] Transcriptional coactivator CAPER (RRM superfamily); [GO:0003676] nucleic acid binding; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [K13091] RNA-binding protein 39; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 35.10 | 0.7975 |
| 40 |
Mapoly0042s0086
| [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K08737] DNA mismatch repair protein MSH6; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PTHR11361:SF31] MUTS HOMOLOG 6, MSH6; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV | 36.66 | 0.7893 |
| 41 |
Mapoly0027s0147
| [PTHR12585] SCC1 / RAD21 FAMILY MEMBER; [PF04824] Conserved region of Rad21 / Rec8 like protein; [GO:0005515] protein binding; [PF04825] N terminus of Rad21 / Rec8 like protein; [K06670] cohesin complex subunit SCC1; [GO:0000228] nuclear chromosome; [KOG1213] Sister chromatid cohesion complex Cohesin, subunit RAD21/SCC1 | 37.95 | 0.7930 |
| 42 |
Mapoly0003s0057
| [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination | 38.42 | 0.8110 |
| 43 |
Mapoly0005s0267
| [PTHR23111] ZINC FINGER PROTEIN; [GO:0008270] zinc ion binding; [PF00641] Zn-finger in Ran binding protein and others | 38.96 | 0.7951 |
| 44 |
Mapoly0162s0013
| [PF00929] Exonuclease; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [PTHR11361:SF34] DNA MISMATCH REPAIR PROTEIN MUTS; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [KOG0218] Mismatch repair MSH3; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV | 40.25 | 0.7957 |
| 45 |
Mapoly0218s0012
| [PTHR15744:SF0] SUBFAMILY NOT NAMED; [PTHR15744] BLOM7 | 40.56 | 0.7827 |
| 46 |
Mapoly0097s0045
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11752] HELICASE SKI2W; [2.7.7.7] DNA-directed DNA polymerase.; [K02349] DNA polymerase theta subunit [EC:2.7.7.7]; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF00476] DNA polymerase family A; [GO:0003676] nucleic acid binding; [GO:0003887] DNA-directed DNA polymerase activity; [KOG0950] DNA polymerase theta/eta, DEAD-box superfamily | 41.89 | 0.7664 |
| 47 |
Mapoly0015s0206
| [PF05236] Transcription initiation factor TFIID component TAF4 family; [GO:0006352] DNA-dependent transcription, initiation; [PTHR15138] FAMILY NOT NAMED; [PF12174] RCD1-SRO-TAF4 (RST) plant domain; [GO:0005669] transcription factor TFIID complex | 41.99 | 0.7890 |
| 48 |
Mapoly0004s0128
| [GO:0005524] ATP binding; [K08864] tousled-like kinase [EC:2.7.11.1]; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PTHR22974] MIXED LINEAGE PROTEIN KINASE; [KOG1151] Tousled-like protein kinase | 43.07 | 0.7770 |
| 49 |
Mapoly0026s0020
| [KOG2253] U1 snRNP complex, subunit SNU71 and related PWI-motif proteins | 44.28 | 0.7910 |
| 50 |
Mapoly0067s0049
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF00580] UvrD/REP helicase N-terminal domain; [PF13361] UvrD-like helicase C-terminal domain; [GO:0016787] hydrolase activity; [GO:0004003] ATP-dependent DNA helicase activity; [PTHR11070] UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER | 45.28 | 0.7490 |
