Guide Gene
- Gene ID
- Mapoly0165s0024
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [GO:0006338] chromatin remodeling; [GO:0043968] histone H2A acetylation; [PF00249] Myb-like DNA-binding domain; [K11324] DNA methyltransferase 1-associated protein 1; [GO:0043967] histone H4 acetylation; [KOG2656] DNA methyltransferase 1-associated protein-1; [GO:0003682] chromatin binding; [PTHR12855] FAMILY NOT NAMED; [GO:0035267] NuA4 histone acetyltransferase complex; [GO:0006281] DNA repair; [PTHR12855:SF10] SUBFAMILY NOT NAMED
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0165s0024 [GO:0006338] chromatin remodeling; [GO:0043968] histone H2A acetylation; [PF00249] Myb-like DNA-binding domain; [K11324] DNA methyltransferase 1-associated protein 1; [GO:0043967] histone H4 acetylation; [KOG2656] DNA methyltransferase 1-associated protein-1; [GO:0003682] chromatin binding; [PTHR12855] FAMILY NOT NAMED; [GO:0035267] NuA4 histone acetyltransferase complex; [GO:0006281] DNA repair; [PTHR12855:SF10] SUBFAMILY NOT NAMED 0.00 1.0000 1 Mapoly0021s0077 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [KOG0796] Spliceosome subunit; [GO:0003729] mRNA binding 1.73 0.8486 2 Mapoly0113s0034 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PF01698] Floricaula / Leafy protein 4.58 0.8249 3 Mapoly0072s0079 [PF11717] RNA binding activity-knot of a chromodomain; [K11339] mortality factor 4-like protein 1; [GO:0005634] nucleus; [PTHR10880] MORTALITY FACTOR 4-LIKE PROTEIN; [PF05712] MRG 4.69 0.8367 4 Mapoly0029s0028 [PF00249] Myb-like DNA-binding domain; [GO:0005515] protein binding; [PF00569] Zinc finger, ZZ type; [GO:0003682] chromatin binding; [GO:0008270] zinc ion binding; [PF04433] SWIRM domain; [PTHR12374] TRANSCRIPTIONAL ADAPTOR 2 (ADA2)-RELATED; [KOG0457] Histone acetyltransferase complex SAGA/ADA, subunit ADA2; [K11314] transcriptional adapter 2-alpha 5.00 0.8309 5 Mapoly0042s0123 [K12875] apoptotic chromatin condensation inducer in the nucleus; [GO:0003676] nucleic acid binding; [PTHR14127] APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; [PF02037] SAP domain 6.93 0.8361 6 Mapoly0074s0043 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [GO:0003729] mRNA binding 8.49 0.8300 7 Mapoly0105s0060 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [K12898] heterogeneous nuclear ribonucleoprotein F/H; [KOG4211] Splicing factor hnRNP-F and related RNA-binding proteins; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED 9.17 0.8332 8 Mapoly0013s0006 [GO:0008270] zinc ion binding; [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PTHR23336] ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3.; [PF07496] CW-type Zinc Finger 9.49 0.8119 9 Mapoly0027s0185 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF39] CDC2-RELATED PROTEIN KINASE; [KOG0600] Cdc2-related protein kinase; [K08819] Cdc2-related kinase, arginine/serine-rich [EC:2.7.11.22]; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 9.95 0.8111 10 Mapoly0012s0200 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [KOG0796] Spliceosome subunit; [GO:0003729] mRNA binding 10.10 0.8021 11 Mapoly0098s0013 [KOG1634] Predicted transcription factor DATF1, contains PHD and TFS2M domains; [PF07500] Transcription factor S-II (TFIIS), central domain; [PTHR11477] TRANSCRIPTION ELONGATION FACTOR S-II; [GO:0006351] transcription, DNA-dependent; [PF07744] SPOC domain 10.58 0.8081 12 Mapoly0092s0032 [PTHR22597] POLYCOMB GROUP PROTEIN; [PTHR22597:SF0] SUBFAMILY NOT NAMED; [PF09733] VEFS-Box of polycomb protein 14.39 0.8173 13 Mapoly0060s0063 - 15.10 0.7794 14 Mapoly0117s0005 [K13109] IK cytokine; [PTHR12765] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [KOG2498] IK cytokine down-regulator of HLA class II; [PF07807] RED-like protein C-terminal region; [PTHR12765:SF5] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [GO:0005634] nucleus; [PF07808] RED-like protein N-terminal region 16.00 0.8034 15 Mapoly0042s0047 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF65] DNA REPAIR AND RECOMBINATION PROTEIN RAD26-RELATED 16.43 0.8017 16 Mapoly0213s0004 [PTHR24012] FAMILY NOT NAMED; [KOG0226] RNA-binding proteins; [GO:0003676] nucleic acid binding; [PTHR24012:SF41] SUBFAMILY NOT NAMED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 16.79 0.7685 17 Mapoly0006s0037 [PF03828] Cid1 family poly A polymerase; [KOG2277] S-M checkpoint control protein CID1 and related nucleotidyltransferases; [PTHR23092] TOPOISOMERASE-RELATED PROTEIN; [PF01909] Nucleotidyltransferase domain; [GO:0016779] nucleotidyltransferase activity; [PTHR23092:SF15] SUBFAMILY NOT NAMED 16.97 0.8222 18 Mapoly0004s0056 [PTHR23424] SERUM AMYLOID A 17.75 0.7707 19 Mapoly0081s0047 [PF00773] RNB domain; [PF13638] PIN domain; [3.1.13.-] Exoribonucleases producing 5'-phosphomonoesters.; [K12585] exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]; [PTHR23355] RIBONUCLEASE; [KOG2102] Exosomal 3'-5' exoribonuclease complex, subunit Rrp44/Dis3 18.17 0.7847 20 Mapoly0104s0010 [PTHR17204:SF5] PRE-MRNA PROCESSING PROTEIN PRP39-RELATED; [K13217] pre-mRNA-processing factor 39; [KOG1258] mRNA processing protein; [GO:0006397] mRNA processing; [GO:0005634] nucleus; [PF05843] Suppressor of forked protein (Suf); [PTHR17204] PRE-MRNA PROCESSING PROTEIN PRP39-RELATED 18.57 0.7953 21 Mapoly0099s0053 [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 20.49 0.8006 22 Mapoly0009s0067 [PTHR31789] FAMILY NOT NAMED 21.17 0.7848 23 Mapoly0005s0051 [GO:0003723] RNA binding; [GO:0000339] RNA cap binding; [GO:0045292] mRNA cis splicing, via spliceosome; [GO:0051028] mRNA transport; [PF02854] MIF4G domain; [GO:0005515] protein binding; [KOG1104] Nuclear cap-binding complex, subunit NCBP1/CBP80; [K12882] nuclear cap-binding protein subunit 1; [GO:0016070] RNA metabolic process; [PTHR12412] CAP BINDING PROTEIN; [GO:0005846] nuclear cap binding complex; [PF09090] MIF4G like; [PF09088] MIF4G like 22.72 0.8109 24 Mapoly0030s0101 [GO:0042393] histone binding; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [K11647] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-]; [KOG0386] Chromatin remodeling complex SWI/SNF, component SWI2 and related ATPases (DNA/RNA helicase superfamily); [PTHR10799:SF209] GLOBAL TRANSCRIPTION ACTIVATOR SNF2L2 (ATP-DEPENDENT HELICASE SMARCA2); [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [PF14619] Snf2-ATP coupling, chromatin remodelling complex 23.37 0.8095 25 Mapoly0005s0151 [KOG2688] Transcription-associated recombination protein - Thp1p; [PTHR12732] UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING; [GO:0005515] protein binding; [PTHR12732:SF0] SUBFAMILY NOT NAMED; [PF01399] PCI domain 23.92 0.7153 26 Mapoly0011s0057 [PF13837] Myb/SANT-like DNA-binding domain 24.74 0.7822 27 Mapoly0042s0086 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K08737] DNA mismatch repair protein MSH6; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PTHR11361:SF31] MUTS HOMOLOG 6, MSH6; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 24.98 0.7936 28 Mapoly0091s0060 - 26.98 0.7410 29 Mapoly0014s0220 [GO:0006355] regulation of transcription, DNA-dependent; [K11308] histone acetyltransferase MYST1 [EC:2.3.1.48]; [PF11717] RNA binding activity-knot of a chromodomain; [PTHR10615] HISTONE ACETYLTRANSFERASE; [GO:0016747] transferase activity, transferring acyl groups other than amino-acyl groups; [GO:0005634] nucleus; [PF01853] MOZ/SAS family; [2.3.1.48] Histone acetyltransferase.; [KOG2747] Histone acetyltransferase (MYST family) 28.14 0.7498 30 Mapoly0048s0100 [PTHR18937:SF8] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC3; [GO:0005524] ATP binding; [KOG0964] Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3); [GO:0008280] cohesin core heterodimer; [GO:0005515] protein binding; [GO:0003682] chromatin binding; [GO:0007064] mitotic sister chromatid cohesion; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain; [K06669] structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) 28.93 0.7926 31 Mapoly0001s0028 [KOG1659] Class 2 transcription repressor NC2, alpha subunit (DRAP1); [GO:0005622] intracellular; [GO:0043565] sequence-specific DNA binding; [PTHR10252:SF5] DR1-ASSOCIATED COREPRESSOR; [PF00808] Histone-like transcription factor (CBF/NF-Y) and archaeal histone; [PTHR10252] HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED 29.93 0.7539 32 Mapoly0036s0123 [GO:0000922] spindle pole; [PTHR19302:SF13] GAMMA-TUBULIN COMPLEX COMPONENT 2 (GCP-2); [PF04130] Spc97 / Spc98 family; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [KOG2001] Gamma-tubulin complex, DGRIP84/SPC97 component 32.17 0.8077 33 Mapoly0011s0104 [GO:0003755] peptidyl-prolyl cis-trans isomerase activity; [PTHR11071] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF00160] Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; [GO:0000413] protein peptidyl-prolyl isomerization; [KOG0546] HSP90 co-chaperone CPR7/Cyclophilin; [GO:0006457] protein folding 34.64 0.7563 34 Mapoly0034s0031 [GO:0007094] mitotic spindle assembly checkpoint; [K06638] mitotic spindle assembly checkpoint protein MAD1; [KOG4593] Mitotic checkpoint protein MAD1; [PTHR23168] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 (MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1); [PF05557] Mitotic checkpoint protein; [PTHR23168:SF0] SUBFAMILY NOT NAMED 35.14 0.8016 35 Mapoly0079s0030 [KOG0543] FKBP-type peptidyl-prolyl cis-trans isomerase; [PTHR10516] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [PF13414] TPR repeat; [GO:0006457] protein folding; [PF00254] FKBP-type peptidyl-prolyl cis-trans isomerase 36.99 0.6812 36 Mapoly0102s0024 [GO:0006355] regulation of transcription, DNA-dependent; [PF14443] DBC1; [KOG3227] Calcium-responsive transcription coactivator; [PTHR14304] P30 DBC PROTEIN 37.79 0.7999 37 Mapoly0028s0116 [PTHR22884] SET DOMAIN PROTEINS 37.82 0.7954 38 Mapoly0051s0067 [PF00651] BTB/POZ domain; [PTHR24411] FAMILY NOT NAMED; [PF00917] MATH domain; [GO:0005515] protein binding; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 38.16 0.7315 39 Mapoly0027s0148 [PTHR22536] LUNG CANCER METASTASIS-RELATED (LCMR1) PROTEIN 39.12 0.7432 40 Mapoly0042s0059 [PTHR16426] UBINUCLEIN/YEMANUCLEIN; [PF08729] HPC2 and ubinuclein domain 39.24 0.7826 41 Mapoly0031s0090 [KOG0379] Kelch repeat-containing proteins; [PF13418] Galactose oxidase, central domain; [PTHR23244] KELCH REPEAT DOMAIN; [PF13415] Galactose oxidase, central domain 41.28 0.7937 42 Mapoly0001s0472 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED 42.43 0.7937 43 Mapoly0068s0092 [GO:0003723] RNA binding; [PF00013] KH domain 43.71 0.7667 44 Mapoly0153s0011 [PF13871] Helicase_C-like; [GO:0006355] regulation of transcription, DNA-dependent; [KOG1513] Nuclear helicase MOP-3/SNO (DEAD-box superfamily); [PTHR12706] STRAWBERRY NOTCH-RELATED; [PF13872] P-loop containing NTP hydrolase pore-1 45.21 0.7913 45 Mapoly0034s0011 [PF09133] SANTA (SANT Associated) 45.83 0.7876 46 Mapoly0039s0014 [PTHR23125] F-BOX/LEUCINE RICH REPEAT PROTEIN 46.10 0.7229 47 Mapoly0008s0081 [PTHR21286] NUCLEAR PORE COMPLEX PROTEIN NUP160; [K14303] nuclear pore complex protein Nup160; [KOG4521] Nuclear pore complex, Nup160 component; [PF11715] Nucleoporin Nup120/160 46.58 0.7875 48 Mapoly0045s0049 - 46.74 0.7293 49 Mapoly0094s0033 [GO:0016567] protein ubiquitination; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [KOG0314] Predicted E3 ubiquitin ligase; [GO:0005634] nucleus; [PF08783] DWNN domain; [GO:0003676] nucleic acid binding; [GO:0004842] ubiquitin-protein ligase activity; [PTHR15439] RETINOBLASTOMA-BINDING PROTEIN 6; [PF04564] U-box domain 46.83 0.7213 50 Mapoly0011s0219 - 47.17 0.7413 51 Mapoly0010s0132 [KOG4825] Component of synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine-binding glycoprotein (43kDa); [PF02151] UvrB/uvrC motif; [GO:0005515] protein binding; [PTHR13371] GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN; [PTHR13371:SF0] SUBFAMILY NOT NAMED 47.28 0.7123 52 Mapoly0158s0032 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [K10728] topoisomerase (DNA) II binding protein 1; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 47.56 0.7473 53 Mapoly0019s0028 [PTHR24011] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [KOG0117] Heterogeneous nuclear ribonucleoprotein R (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 48.44 0.7659 54 Mapoly0070s0053 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF09382] RQC domain; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [K10901] bloom syndrome protein [EC:3.6.4.12]; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 49.48 0.7833 55 Mapoly0023s0143 [GO:0005524] ATP binding; [PTHR23073] 26S PROTEASE REGULATORY SUBUNIT; [PTHR23073:SF18] SUBFAMILY NOT NAMED; [PF00004] ATPase family associated with various cellular activities (AAA) 49.57 0.7793 56 Mapoly0024s0108 [PF13371] Tetratricopeptide repeat; [PTHR23082] TRANSCRIPTION INITIATION FACTOR IIIC (TFIIIC), POLYPEPTIDE 3-RELATED; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13174] Tetratricopeptide repeat; [KOG2076] RNA polymerase III transcription factor TFIIIC 49.61 0.7307 57 Mapoly0009s0028 [PTHR22812] CHROMOBOX PROTEIN; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain 50.99 0.7657 58 Mapoly0063s0071 [GO:0005515] protein binding; [K12176] COP9 signalosome complex subunit 2; [KOG1464] COP9 signalosome, subunit CSN2; [PF01399] PCI domain; [PTHR10678] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 52.54 0.7395 59 Mapoly0048s0088 [PF00397] WW domain; [GO:0005515] protein binding; [K12824] transcription elongation regulator 1; [PTHR15377:SF3] SUBFAMILY NOT NAMED; [PTHR15377] TRANSCRIPTION FACTOR CA150B RELATEDTCERG1; [PF01846] FF domain; [KOG0155] Transcription factor CA150 53.95 0.7747 60 Mapoly0130s0046 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF14493] Helix-turn-helix domain; [PF09382] RQC domain; [K10900] werner syndrome ATP-dependent helicase [EC:3.6.4.12]; [KOG0353] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 54.86 0.7730 61 Mapoly0010s0036 [KOG2002] TPR-containing nuclear phosphoprotein that regulates K(+) uptake; [PF07719] Tetratricopeptide repeat; [PTHR14027:SF2] TPR REPEAT NUCLEAR PHOSPHOPROTEIN; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13174] Tetratricopeptide repeat; [PF13181] Tetratricopeptide repeat; [PF13424] Tetratricopeptide repeat; [PTHR14027] TPR REPEAT NUCLEAR PHOSPHOPROTEIN/CTR9; [PF00515] Tetratricopeptide repeat 55.42 0.7821 62 Mapoly0009s0015 [PF00078] Reverse transcriptase (RNA-dependent DNA polymerase); [PTHR12066] TELOMERASE REVERSE TRANSCRIPTASE; [GO:0003964] RNA-directed DNA polymerase activity; [K11126] telomerase reverse transcriptase [EC:2.7.7.49]; [PTHR12066:SF0] SUBFAMILY NOT NAMED; [2.7.7.49] RNA-directed DNA polymerase.; [PF12009] Telomerase ribonucleoprotein complex - RNA binding domain; [KOG1005] Telomerase catalytic subunit/reverse transcriptase TERT 55.75 0.7730 63 Mapoly0051s0023 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III 58.50 0.7878 64 Mapoly0038s0101 [K12837] splicing factor U2AF 65 kDa subunit; [PTHR23139] RNA-BINDING PROTEIN; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG0120] Splicing factor U2AF, large subunit (RRM superfamily); [GO:0003676] nucleic acid binding; [PTHR23139:SF9] SPLICING FACTOR U2AF LARGE SUBUNIT; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 60.40 0.7679 65 Mapoly0001s0493 [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [K12858] ATP-dependent RNA helicase DDX23/PRP28 [EC:3.6.4.13]; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [KOG0333] U5 snRNP-like RNA helicase subunit; [PTHR24031:SF23] SUBFAMILY NOT NAMED 60.97 0.7540 66 Mapoly0004s0286 [PTHR12663:SF0] SUBFAMILY NOT NAMED; [K11267] sister chromatid cohesion protein PDS5; [PTHR12663] ANDROGEN INDUCED INHIBITOR OF PROLIFERATION (AS3) / PDS5-RELATED; [KOG1525] Sister chromatid cohesion complex Cohesin, subunit PDS5 61.64 0.7751 67 Mapoly0016s0079 [GO:0005524] ATP binding; [KOG2680] DNA helicase TIP49, TBP-interacting protein; [3.6.4.12] DNA helicase.; [PF06068] TIP49 C-terminus; [GO:0043141] ATP-dependent 5'-3' DNA helicase activity; [K11338] RuvB-like protein 2 [EC:3.6.4.12]; [GO:0003678] DNA helicase activity; [PTHR11093] RUVB-RELATED REPTIN AND PONTIN; [PTHR11093:SF2] RUVB-LIKE 2 (REPTIN) 63.06 0.7508 68 Mapoly0004s0202 - 63.25 0.7659 69 Mapoly0005s0161 [GO:0003677] DNA binding; [PTHR13451:SF0] SUBFAMILY NOT NAMED; [3.1.22.-] Endodeoxyribonucleases producing other than 5'-phosphomonoesters.; [K08991] crossover junction endonuclease MUS81 [EC:3.1.22.-]; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PF02732] ERCC4 domain 64.36 0.7303 70 Mapoly0005s0045 [PF15628] RRM in Demeter; [PTHR10359] A/G-SPECIFIC ADENINE GLYCOSYLASE/ENDONUCLEASE III 64.62 0.7596 71 Mapoly0029s0111 [PTHR22836] WD40 REPEAT PROTEIN; [GO:0005515] protein binding; [KOG0284] Polyadenylation factor I complex, subunit PFS2; [PF00400] WD domain, G-beta repeat 64.90 0.7082 72 Mapoly0226s0007 [PF00817] impB/mucB/samB family; [2.7.7.7] DNA-directed DNA polymerase.; [GO:0006281] DNA repair; [PF11799] impB/mucB/samB family C-terminal domain; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [PTHR11076:SF11] DNA POLYMERASE ETA; [GO:0003887] DNA-directed DNA polymerase activity; [GO:0003684] damaged DNA binding; [K03509] DNA polymerase eta subunit [EC:2.7.7.7] 65.16 0.6958 73 Mapoly0032s0156 [PF14652] Domain of unknown function (DUF4457); [PTHR21534] UNCHARACTERIZED; [PTHR21534:SF0] SUBFAMILY NOT NAMED 65.67 0.7620 74 Mapoly0140s0030 [PF00773] RNB domain; [PTHR23355] RIBONUCLEASE; [KOG2102] Exosomal 3'-5' exoribonuclease complex, subunit Rrp44/Dis3 65.67 0.7473 75 Mapoly0070s0015 [PF12774] Hydrolytic ATP binding site of dynein motor region D1; [PF12780] P-loop containing dynein motor region D4; [PTHR10676:SF137] DYNEIN HEAVY CHAIN 1, AXONEMAL-RELATED; [PF12775] P-loop containing dynein motor region D3; [GO:0005858] axonemal dynein complex; [GO:0030286] dynein complex; [PTHR10676] DYNEIN HEAVY CHAIN FAMILY PROTEIN; [PF03028] Dynein heavy chain and region D6 of dynein motor; [GO:0016887] ATPase activity; [KOG3595] Dyneins, heavy chain; [PF12777] Microtubule-binding stalk of dynein motor; [GO:0007018] microtubule-based movement; [PF12781] ATP-binding dynein motor region D5; [PF08393] Dynein heavy chain, N-terminal region 2; [GO:0003341] cilium movement; [GO:0003777] microtubule motor activity 66.74 0.7195 76 Mapoly0121s0014 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PTHR23329] TUFTELIN-INTERACTING PROTEIN 11-RELATED; [PF07842] GC-rich sequence DNA-binding factor-like protein; [KOG2184] Tuftelin-interacting protein TIP39, contains G-patch domain; [PF01585] G-patch domain; [PF12457] Tuftelin interacting protein N terminal; [GO:0005634] nucleus; [GO:0003676] nucleic acid binding; [PTHR23329:SF1] TUFTELIN INTERACTING PROTEIN 11; [K13103] tuftelin-interacting protein 11 68.16 0.7687 77 Mapoly0074s0062 [PF00011] Hsp20/alpha crystallin family 68.89 0.5806 78 Mapoly0033s0004 - 69.45 0.7655 79 Mapoly0009s0245 [PF00397] WW domain; [GO:0005515] protein binding; [KOG0144] RNA-binding protein CUGBP1/BRUNO (RRM superfamily); [PTHR24011] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 70.00 0.7326 80 Mapoly0143s0029 - 70.29 0.6992 81 Mapoly0037s0008 [PF10250] GDP-fucose protein O-fucosyltransferase; [PTHR31741] FAMILY NOT NAMED 70.46 0.6626 82 Mapoly0063s0006 [KOG2217] U4/U6.U5 snRNP associated protein; [K11984] U4/U6.U5 tri-snRNP-associated protein 1; [PTHR14152:SF5] SUBFAMILY NOT NAMED; [PTHR14152] SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES; [PF03343] SART-1 family 72.46 0.7585 83 Mapoly0010s0030 [PTHR22880] FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; [GO:0005515] protein binding; [PF00439] Bromodomain 72.94 0.7375 84 Mapoly0007s0100 [PTHR15828] CYTOKINE RECEPTOR-LIKE FACTOR 3 74.51 0.7546 85 Mapoly0015s0191 [PTHR14270:SF0] SUBFAMILY NOT NAMED; [PTHR14270] UNCHARACTERIZED; [KOG4181] Uncharacterized conserved protein 75.52 0.7241 86 Mapoly0019s0115 [PTHR23002] ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN; [PF14392] Zinc knuckle; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding 75.91 0.7296 87 Mapoly0056s0030 [KOG1040] Polyadenylation factor I complex, subunit, Yth1 (CPSF subunit); [PTHR12357] YTH (YT521-B HOMOLOGY) DOMAIN-CONTAINING; [PF04146] YT521-B-like domain; [PTHR12357:SF3] SPLICING FACTOR YT521-B 76.84 0.7150 88 Mapoly0002s0125 [PTHR25040] FAMILY NOT NAMED; [PF11926] Domain of unknown function (DUF3444); [PTHR25040:SF79] SUBFAMILY NOT NAMED; [PF00226] DnaJ domain 78.49 0.7711 89 Mapoly0015s0126 [GO:0008641] small protein activating enzyme activity; [GO:0005524] ATP binding; [K10685] ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19]; [KOG2013] SMT3/SUMO-activating complex, catalytic component UBA2; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [PF14732] Ubiquitin/SUMO-activating enzyme ubiquitin-like domain 79.23 0.7485 90 Mapoly0050s0101 [3.4.21.48] Cerevisin.; [K01336] cerevisin [EC:3.4.21.48]; [GO:0004252] serine-type endopeptidase activity; [PF00082] Subtilase family; [PF00090] Thrombospondin type 1 domain; [PF00053] Laminin EGF-like (Domains III and V); [GO:0006508] proteolysis; [PTHR10795] PROPROTEIN CONVERTASE SUBTILISIN/KEXIN 79.32 0.7259 91 Mapoly0013s0166 [KOG1731] FAD-dependent sulfhydryl oxidase/quiescin and related proteins; [GO:0016972] thiol oxidase activity; [GO:0055114] oxidation-reduction process; [GO:0045454] cell redox homeostasis; [PTHR22897:SF8] SUBFAMILY NOT NAMED; [PTHR22897] QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE; [PF04777] Erv1 / Alr family; [PF00085] Thioredoxin 79.82 0.7019 92 Mapoly0004s0169 [GO:0003677] DNA binding; [GO:0006338] chromatin remodeling; [GO:0005524] ATP binding; [PF09110] HAND; [K11654] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]; [GO:0043044] ATP-dependent chromatin remodeling; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [GO:0005634] nucleus; [PTHR10799:SF73] ISWI CHROMATIN-REMODELING COMPLEX ATPASE ISW1; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [KOG0385] Chromatin remodeling complex WSTF-ISWI, small subunit; [GO:0003676] nucleic acid binding; [GO:0031491] nucleosome binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [PF09111] SLIDE 80.61 0.7615 93 Mapoly0043s0012 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [K13123] G patch domain-containing protein 1; [PTHR13384] FAMILY NOT NAMED; [KOG2138] Predicted RNA binding protein, contains G-patch domain; [PF07713] Protein of unknown function (DUF1604); [PF01805] Surp module 80.83 0.7653 94 Mapoly0001s0378 [PTHR32086] FAMILY NOT NAMED; [K10891] fanconi anemia group D2 protein; [GO:0006281] DNA repair; [KOG4712] Uncharacterized conserved protein; [PF14631] Fanconi anaemia protein FancD2 nuclease 81.81 0.7508 95 Mapoly0032s0110 [PTHR16219] FAMILY NOT NAMED; [PF14735] HAUS augmin-like complex subunit 4; [GO:0051225] spindle assembly; [GO:0070652] HAUS complex; [PTHR16219:SF1] SUBFAMILY NOT NAMED 82.49 0.6735 96 Mapoly0079s0042 [GO:0003723] RNA binding; [KOG2202] U2 snRNP splicing factor, small subunit, and related proteins; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PTHR12620] U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT; [GO:0005634] nucleus; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [GO:0046872] metal ion binding 82.85 0.7424 97 Mapoly0186s0008 [GO:0003676] nucleic acid binding; [KOG0106] Alternative splicing factor SRp55/B52/SRp75 (RRM superfamily); [PTHR10548] SPLICING FACTOR, ARGININE/SERINE-RICH; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 83.12 0.7163 98 Mapoly0148s0032 [PF01480] PWI domain; [PTHR18806:SF4] SUBFAMILY NOT NAMED; [GO:0006397] mRNA processing; [PTHR18806] RBM25 PROTEIN; [GO:0003676] nucleic acid binding; [K12822] RNA-binding protein 25; [KOG2253] U1 snRNP complex, subunit SNU71 and related PWI-motif proteins; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 84.10 0.7520 99 Mapoly0007s0146 [KOG4374] RNA-binding protein Bicaudal-C; [PTHR15457] SEC-23 INTERACTING PROTEIN P125; [PF00536] SAM domain (Sterile alpha motif) 84.17 0.7068 100 Mapoly0024s0131 - 84.94 0.7526 101 Mapoly0033s0098 [PTHR16047] RFWD3 PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PTHR16047:SF7] RFWD3 PROTEIN-RELATED; [KOG1645] RING-finger-containing E3 ubiquitin ligase 85.16 0.7482 102 Mapoly0030s0009 [PF00505] HMG (high mobility group) box; [KOG0526] Nucleosome-binding factor SPN, POB3 subunit; [PF03531] Structure-specific recognition protein (SSRP1); [PTHR13711:SF39] SUBFAMILY NOT NAMED; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [PF08512] Histone chaperone Rttp106-like; [K09272] structure-specific recognition protein 1 86.74 0.7474 103 Mapoly0068s0038 [PTHR13413] YLP MOTIF CONTAINING PROTEIN (NUCLEAR PROTEIN ZAP); [PTHR13413:SF0] SUBFAMILY NOT NAMED; [GO:0005634] nucleus 87.50 0.7523 104 Mapoly0014s0073 [KOG1663] O-methyltransferase; [GO:0008171] O-methyltransferase activity; [PTHR10509] O-METHYLTRANSFERASE-RELATED; [PF01596] O-methyltransferase 88.26 0.6928 105 Mapoly0001s0120 [PF00225] Kinesin motor domain; [GO:0007018] microtubule-based movement; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0008017] microtubule binding; [KOG0242] Kinesin-like protein; [GO:0003777] microtubule motor activity; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex 88.54 0.7073 106 Mapoly0051s0020 [PTHR12785:SF6] SUBFAMILY NOT NAMED; [K12829] splicing factor 3B subunit 2; [GO:0005634] nucleus; [PF04046] PSP; [KOG2330] Splicing factor 3b, subunit 2; [PTHR12785] FAMILY NOT NAMED; [PF04037] Domain of unknown function (DUF382) 89.29 0.7520 107 Mapoly0033s0045 - 89.77 0.7073 108 Mapoly0068s0104 [PF04802] Component of IIS longevity pathway SMK-1; [KOG2175] Protein predicted to be involved in carbohydrate metabolism; [PTHR23318] ATP SYNTHASE GAMMA-RELATED 90.53 0.7631 109 Mapoly0001s0525 [K14408] cleavage stimulation factor subunit 3; [GO:0006397] mRNA processing; [GO:0005634] nucleus; [KOG1914] mRNA cleavage and polyadenylation factor I complex, subunit RNA14; [PTHR19980] RNA CLEAVAGE STIMULATION FACTOR; [PF05843] Suppressor of forked protein (Suf) 92.03 0.7508 110 Mapoly0033s0111 [PTHR13587] FAMILY NOT NAMED; [K13140] integrator complex subunit 3; [PF10189] Conserved protein (DUF2356); [KOG4262] Uncharacterized conserved protein 93.83 0.7544 111 Mapoly0105s0035 [PTHR12341] 5'-3' EXORIBONUCLEASE; [PF03159] XRN 5'-3' exonuclease N-terminus; [K12619] 5'-3' exoribonuclease 2 [EC:3.1.13.-]; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [3.1.13.-] Exoribonucleases producing 5'-phosphomonoesters.; [GO:0003676] nucleic acid binding; [GO:0004527] exonuclease activity 94.47 0.7477 112 Mapoly0039s0062 [GO:0005524] ATP binding; [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [GO:0003676] nucleic acid binding; [KOG0922] DEAH-box RNA helicase; [PF07717] Oligonucleotide/oligosaccharide-binding (OB)-fold 95.20 0.7073 113 Mapoly4108s0001 [PTHR23140] RNA PROCESSING PROTEIN LD23810P 95.81 0.7041 114 Mapoly0051s0060 [PTHR31399:SF0] SUBFAMILY NOT NAMED; [PF03121] Herpesviridae UL52/UL70 DNA primase; [GO:0006260] DNA replication; [GO:0003896] DNA primase activity; [PTHR31399] FAMILY NOT NAMED 96.28 0.7318 115 Mapoly0062s0092 [PF00929] Exonuclease; [K14570] RNA exonuclease 1 [EC:3.1.-.-]; [3.1.-.-] Acting on ester bonds.; [PTHR12801] EXONUCLEASE; [KOG2249] 3'-5' exonuclease 97.08 0.7103 116 Mapoly0014s0195 [PTHR10641:SF17] CELL DIVISION CYCLE 5-LIKE PROTEIN; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [PF13921] Myb-like DNA-binding domain; [PF11831] pre-mRNA splicing factor component; [K12860] pre-mRNA-splicing factor CDC5/CEF1 97.50 0.7336 117 Mapoly0063s0093 [PF07714] Protein tyrosine kinase; [KOG0192] Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs; [PTHR23257] SERINE-THREONINE PROTEIN KINASE; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [GO:0005543] phospholipid binding; [PF07651] ANTH domain 97.71 0.6870 118 Mapoly0131s0025 [PF08324] PUL domain; [KOG0301] Phospholipase A2-activating protein (contains WD40 repeats); [PTHR19849] PHOSPHOLIPASE A-2-ACTIVATING PROTEIN; [PTHR19849:SF0] SUBFAMILY NOT NAMED; [K14018] phospholipase A-2-activating protein; [GO:0005515] protein binding; [PF09070] PFU (PLAA family ubiquitin binding); [PF00400] WD domain, G-beta repeat 99.73 0.6931 119 Mapoly0012s0166 [PF09405] CASC3/Barentsz eIF4AIII binding; [PTHR22814:SF47] HEAVY-METAL-ASSOCIATED DOMAIN-CONTAINING PROTEIN; [PTHR22814] COPPER TRANSPORT PROTEIN ATOX1-RELATED 101.42 0.7218 120 Mapoly0114s0035 [PTHR31169] FAMILY NOT NAMED; [PF10497] Zinc-finger domain of monoamine-oxidase A repressor R1 102.69 0.7298 121 Mapoly0116s0041 [PF13297] Telomere stability C-terminal; [PTHR12786:SF2] SPLICING FACTOR 3A; [PF12108] Splicing factor SF3a60 binding domain; [KOG2636] Splicing factor 3a, subunit 3; [PTHR12786] SPLICING FACTOR SF3A-RELATED; [K12827] splicing factor 3A subunit 3; [PF11931] Domain of unknown function (DUF3449) 103.25 0.7441 122 Mapoly0091s0014 [PTHR12596:SF1] GB DEF: T27C4.14 PROTEIN; [PTHR12596] EXPORTIN 4,7-RELATED; [KOG4541] Nuclear transport receptor exportin 4 (importin beta superfamily) 103.69 0.7297 123 Mapoly0021s0042 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [KOG0298] DEAD box-containing helicase-like transcription factor/DNA repair protein; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [PF00271] Helicase conserved C-terminal domain 103.83 0.7299 124 Mapoly0054s0103 [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [3.6.4.13] RNA helicase.; [KOG0923] mRNA splicing factor ATP-dependent RNA helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [PF07717] Oligonucleotide/oligosaccharide-binding (OB)-fold; [K12813] pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:3.6.4.13] 105.32 0.7378 125 Mapoly0069s0077 [PTHR11736:SF14] MAGE-RELATED; [PTHR11736] MELANOMA-ASSOCIATED ANTIGEN (MAGE ANTIGEN); [PF01454] MAGE family; [KOG4562] Uncharacterized conserved protein (tumor-rejection antigen MAGE in humans) 105.33 0.6722 126 Mapoly0135s0035 [GO:0003676] nucleic acid binding; [PF02037] SAP domain 107.47 0.7314 127 Mapoly0050s0019 [PF08642] Histone deacetylation protein Rxt3; [KOG4843] Uncharacterized conserved protein 109.24 0.7096 128 Mapoly0109s0055 [PF05186] Dpy-30 motif 111.09 0.7324 129 Mapoly0042s0049 - 113.13 0.7443 130 Mapoly0058s0099 [GO:0005524] ATP binding; [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [PF00035] Double-stranded RNA binding motif; [KOG0920] ATP-dependent RNA helicase A; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [GO:0003676] nucleic acid binding; [PF07717] Oligonucleotide/oligosaccharide-binding (OB)-fold 114.32 0.7194 131 Mapoly0046s0104 [PF00628] PHD-finger; [GO:0005515] protein binding 114.49 0.7289 132 Mapoly0004s0250 [GO:0005643] nuclear pore; [PF07817] GLE1-like protein; [GO:0016973] poly(A)+ mRNA export from nucleus; [KOG2412] Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor; [PTHR12960:SF0] SUBFAMILY NOT NAMED; [PTHR12960] GLE-1-RELATED 115.00 0.7294 133 Mapoly0041s0101 [GO:0005524] ATP binding; [K02603] origin recognition complex subunit 1; [PF01426] BAH domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [GO:0003682] chromatin binding; [PTHR10763:SF6] ORIGIN RECOGNITION COMPLEX SUBUNIT 1; [KOG1514] Origin recognition complex, subunit 1, and related proteins; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR10763] CELL DIVISION CONTROL PROTEIN 6-RELATED 115.23 0.6971 134 Mapoly0073s0063 [GO:0016020] membrane; [GO:0005524] ATP binding; [GO:0017038] protein import; [PF07516] SecA Wing and Scaffold domain; [PTHR30612] SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM; [PF07517] SecA DEAD-like domain; [PF01043] SecA preprotein cross-linking domain; [K03070] preprotein translocase subunit SecA 116.62 0.6275 135 Mapoly0067s0005 [PTHR24012] FAMILY NOT NAMED; [PTHR24012:SF39] SUBFAMILY NOT NAMED; [KOG0147] Transcriptional coactivator CAPER (RRM superfamily); [GO:0003676] nucleic acid binding; [PF13893] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [K13091] RNA-binding protein 39; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 116.77 0.7325 136 Mapoly0075s0051 [GO:0006355] regulation of transcription, DNA-dependent; [PF02309] AUX/IAA family; [GO:0005634] nucleus; [PTHR31384] FAMILY NOT NAMED 117.98 0.7424 137 Mapoly0060s0055 [PF07748] Glycosyl hydrolases family 38 C-terminal domain; [GO:0015923] mannosidase activity; [KOG1959] Glycosyl hydrolase, family 38 - alpha-mannosidase; [PTHR11607] ALPHA-MANNOSIDASE; [GO:0004559] alpha-mannosidase activity; [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [GO:0006013] mannose metabolic process; [PF09261] Alpha mannosidase, middle domain; [GO:0005975] carbohydrate metabolic process; [GO:0008270] zinc ion binding; [PF01074] Glycosyl hydrolases family 38 N-terminal domain 119.22 0.6796 138 Mapoly0131s0010 [PTHR15921:SF3] SUBFAMILY NOT NAMED; [KOG2071] mRNA cleavage and polyadenylation factor I/II complex, subunit Pcf11; [PF04818] RNA polymerase II-binding domain.; [PTHR15921] PRE-MRNA CLEAVAGE COMPLEX II 119.83 0.7436 139 Mapoly0001s0015 [PTHR13555] C2H2 ZINC FINGER CGI-62-RELATED 119.95 0.6866 140 Mapoly0061s0078 [KOG1361] Predicted hydrolase involved in interstrand cross-link repair; [PTHR23240] DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; [PF12706] Beta-lactamase superfamily domain; [PF07522] DNA repair metallo-beta-lactamase; [PF00536] SAM domain (Sterile alpha motif) 119.96 0.7243 141 Mapoly0005s0061 [PF00089] Trypsin; [PTHR22939] SERINE PROTEASE FAMILY S1C HTRA-RELATED; [GO:0005515] protein binding; [PF13180] PDZ domain; [KOG1320] Serine protease; [GO:0004252] serine-type endopeptidase activity; [GO:0006508] proteolysis 120.51 0.7179 142 Mapoly0065s0067 [PTHR13165] ARSENITE-RESISTANCE PROTEIN 2; [PF12066] Domain of unknown function (DUF3546); [PF04959] Arsenite-resistance protein 2; [KOG2295] C2H2 Zn-finger protein; [PTHR13165:SF0] SUBFAMILY NOT NAMED 121.50 0.7255 143 Mapoly0133s0013 [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10615] HISTONE ACETYLTRANSFERASE; [PF00856] SET domain 121.86 0.7411 144 Mapoly0080s0034 [2.1.1.43] Histone-lysine N-methyltransferase.; [KOG1082] Histone H3 (Lys9) methyltransferase SUV39H1/Clr4, required for transcriptional silencing; [K11419] histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43]; [PF05033] Pre-SET motif; [GO:0005515] protein binding; [PF00856] SET domain; [GO:0008270] zinc ion binding; [GO:0018024] histone-lysine N-methyltransferase activity; [PTHR22884] SET DOMAIN PROTEINS; [GO:0005634] nucleus; [GO:0034968] histone lysine methylation; [PF13771] PHD-like zinc-binding domain 122.05 0.7194 145 Mapoly0068s0031 [KOG1882] Transcriptional regulator SNIP1, contains FHA domain; [GO:0005515] protein binding; [K13108] smad nuclear-interacting protein 1; [PF00498] FHA domain; [PTHR23308] NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 122.52 0.7174 146 Mapoly0013s0183 [KOG2739] Leucine-rich acidic nuclear protein; [PF14580] Leucine-rich repeat; [PTHR11375] ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 122.60 0.7050 147 Mapoly0033s0057 [2.3.1.-] Transferring groups other than amino-acyl groups.; [PTHR11076:SF1] ESTABLISHMENT OF COHESION 1 (ECO1) HOMOLOG; [PF13880] ESCO1/2 acetyl-transferase; [PF13878] zinc-finger of acetyl-transferase ESCO; [KOG3014] Protein involved in establishing cohesion between sister chromatids during DNA replication; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [K11268] N-acetyltransferase [EC:2.3.1.-] 124.12 0.7466 148 Mapoly0209s0009 [PF04266] ASCH domain 124.32 0.6687 149 Mapoly0001s0195 [GO:0070985] TFIIK complex; [GO:0006355] regulation of transcription, DNA-dependent; [GO:0016538] cyclin-dependent protein serine/threonine kinase regulator activity; [GO:0019901] protein kinase binding; [PTHR10026:SF8] CYCLIN H; [PF00134] Cyclin, N-terminal domain; [PTHR10026] CYCLIN; [KOG2496] Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, cyclin H subunit; [GO:0006351] transcription, DNA-dependent; [GO:0000079] regulation of cyclin-dependent protein serine/threonine kinase activity 124.97 0.6687 150 Mapoly0014s0037 [PTHR22850] WD40 REPEAT FAMILY 127.14 0.6580 151 Mapoly0016s0130 [PF14817] HAUS augmin-like complex subunit 5; [GO:0051225] spindle assembly 127.81 0.7327 152 Mapoly0001s0024 [GO:0005634] nucleus; [GO:0003677] DNA binding; [KOG2402] Paf1/RNA polymerase II complex, RTF1 component (involved in regulation of TATA box-binding protein); [GO:0006352] DNA-dependent transcription, initiation; [GO:0016570] histone modification; [PTHR13115:SF8] SUBFAMILY NOT NAMED; [PF03126] Plus-3 domain; [PTHR13115] UNCHARACTERIZED 128.15 0.7175 153 Mapoly0006s0231 [KOG0123] Polyadenylate-binding protein (RRM superfamily); [PTHR24011] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF07744] SPOC domain; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 130.16 0.7428 154 Mapoly0092s0013 [GO:0003723] RNA binding; [PTHR13326] TRNA PSEUDOURIDINE SYNTHASE D; [GO:0001522] pseudouridine synthesis; [GO:0009451] RNA modification; [PF01142] tRNA pseudouridine synthase D (TruD); [GO:0009982] pseudouridine synthase activity; [KOG2339] Uncharacterized conserved protein 130.49 0.7029 155 Mapoly0055s0120 - 131.45 0.7187 156 Mapoly0050s0010 [KOG2829] E2F-like protein; [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [PTHR12548] TRANSCRIPTION FACTOR DP; [PF08781] Transcription factor DP; [GO:0007049] cell cycle 132.45 0.6444 157 Mapoly0041s0116 [PTHR31246] FAMILY NOT NAMED; [PF07058] Myosin II heavy chain-like; [GO:0008017] microtubule binding; [GO:0007010] cytoskeleton organization 133.99 0.6709 158 Mapoly0072s0016 [GO:0005515] protein binding; [PTHR15398] BROMODOMAIN-CONTAINING PROTEIN 8; [PF00439] Bromodomain; [K11321] bromodomain-containing protein 8; [PTHR15398:SF0] SUBFAMILY NOT NAMED 134.08 0.6939 159 Mapoly0015s0183 [GO:0000922] spindle pole; [PF04130] Spc97 / Spc98 family; [GO:0000226] microtubule cytoskeleton organization; [GO:0005815] microtubule organizing center; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN 134.49 0.6526 160 Mapoly0008s0250 [PTHR24007] BRCA1-ASSOCIATED PROTEIN; [PF00917] MATH domain; [GO:0005515] protein binding; [GO:0006281] DNA repair; [PF14631] Fanconi anaemia protein FancD2 nuclease; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 134.92 0.7125 161 Mapoly0162s0013 [PF00929] Exonuclease; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [PTHR11361:SF34] DNA MISMATCH REPAIR PROTEIN MUTS; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [KOG0218] Mismatch repair MSH3; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 135.94 0.7265 162 Mapoly0209s0008 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF67] DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 136.56 0.7433 163 Mapoly0001s0263 [PF08766] DEK C terminal domain; [GO:0005515] protein binding; [KOG1946] RNA polymerase I transcription factor UAF; [PF02201] SWIB/MDM2 domain; [PTHR13844] BRG-1 ASSOCIATED FACTOR 60 (BAF60) 136.68 0.6157 164 Mapoly0011s0138 [PF12717] non-SMC mitotic condensation complex subunit 1; [K13141] integrator complex subunit 4; [PTHR20938] UNCHARACTERIZED; [PTHR20938:SF0] SUBFAMILY NOT NAMED 136.82 0.7459 165 Mapoly0122s0062 [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 137.52 0.7371 166 Mapoly0027s0147 [PTHR12585] SCC1 / RAD21 FAMILY MEMBER; [PF04824] Conserved region of Rad21 / Rec8 like protein; [GO:0005515] protein binding; [PF04825] N terminus of Rad21 / Rec8 like protein; [K06670] cohesin complex subunit SCC1; [GO:0000228] nuclear chromosome; [KOG1213] Sister chromatid cohesion complex Cohesin, subunit RAD21/SCC1 137.99 0.7183 167 Mapoly0036s0107 [K09422] myb proto-oncogene protein, plant; [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding; [PF13921] Myb-like DNA-binding domain 138.52 0.7283 168 Mapoly0038s0047 [PTHR20929] LUNG ADENOMA SUSCEPTIBILITY 1-RELATED 138.69 0.7061 169 Mapoly0112s0002 [PF14750] Integrator complex subunit 2; [K13139] integrator complex subunit 2; [GO:0032039] integrator complex 139.98 0.6957 170 Mapoly0051s0016 [PF13831] PHD-finger; [PF05964] F/Y-rich N-terminus; [GO:0005515] protein binding; [PF13832] PHD-zinc-finger like domain; [PF00856] SET domain; [PTHR13793] PHD FINGER PROTEINS; [PF00855] PWWP domain; [GO:0005634] nucleus; [PF05965] F/Y rich C-terminus 140.79 0.7312 171 Mapoly0026s0020 [KOG2253] U1 snRNP complex, subunit SNU71 and related PWI-motif proteins 140.83 0.7191 172 Mapoly0099s0003 [GO:0000922] spindle pole; [PF04130] Spc97 / Spc98 family; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN 141.14 0.7052 173 Mapoly0023s0117 [PTHR10139] DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11A; [PF04152] Mre11 DNA-binding presumed domain; [KOG2310] DNA repair exonuclease MRE11; [GO:0006259] DNA metabolic process; [PF00149] Calcineurin-like phosphoesterase; [GO:0006302] double-strand break repair; [GO:0016787] hydrolase activity; [GO:0030145] manganese ion binding; [GO:0005634] nucleus; [GO:0004527] exonuclease activity; [K10865] double-strand break repair protein MRE11; [GO:0004519] endonuclease activity 141.46 0.7132 174 Mapoly0045s0061 [KOG1081] Transcription factor NSD1 and related SET domain proteins; [GO:0005515] protein binding; [PF00856] SET domain; [PTHR22884] SET DOMAIN PROTEINS 141.49 0.7205 175 Mapoly0001s0127 [KOG1493] Anaphase-promoting complex (APC), subunit 11; [PF13923] Zinc finger, C3HC4 type (RING finger); [PTHR15242] SPLICING FACTOR, ARGININE/SERINE-RICH 2,RNAP C-TERM INTERACTING PROTEIN; [PF00628] PHD-finger; [GO:0005515] protein binding 142.25 0.6453 176 Mapoly0032s0010 - 142.71 0.7390 177 Mapoly0063s0002 [PF01480] PWI domain; [K13171] serine/arginine repetitive matrix protein 1; [PTHR23148] SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN; [GO:0006397] mRNA processing; [KOG2146] Splicing coactivator SRm160/300, subunit SRm160 (contains PWI domain) 144.50 0.7075 178 Mapoly0035s0108 [GO:0005524] ATP binding; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23074] AAA ATPASE; [KOG0740] AAA+-type ATPase; [PF09336] Vps4 C terminal oligomerisation domain; [PTHR23074:SF17] FIDGETIN LIKE-1 144.91 0.7116 179 Mapoly0054s0029 [3.1.26.11] Ribonuclease Z.; [PTHR12553] RIBONUCLEASE Z; [K00784] ribonuclease Z [EC:3.1.26.11]; [PF12706] Beta-lactamase superfamily domain 145.19 0.6945 180 Mapoly0187s0003 [PTHR22880] FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; [K06062] histone acetyltransferase [EC:2.3.1.48]; [GO:0005515] protein binding; [PF00439] Bromodomain; [GO:0008080] N-acetyltransferase activity; [PF00583] Acetyltransferase (GNAT) family; [2.3.1.48] Histone acetyltransferase. 145.97 0.6940 181 Mapoly0013s0140 [K13107] RNA-binding motif protein, X-linked 2; [KOG0126] Predicted RNA-binding protein (RRM superfamily); [PTHR23139] RNA-BINDING PROTEIN; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 146.37 0.6317 182 Mapoly0016s0027 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PF02170] PAZ domain; [PTHR14950] HELICASE-RELATED; [GO:0005515] protein binding; [PF00636] Ribonuclease III domain; [GO:0004525] ribonuclease III activity 147.36 0.6517 183 Mapoly0133s0014 [PTHR23125] F-BOX/LEUCINE RICH REPEAT PROTEIN 147.78 0.6360 184 Mapoly0151s0018 [PF00917] MATH domain; [GO:0005515] protein binding; [PTHR24006] FAMILY NOT NAMED 148.16 0.7329 185 Mapoly0010s0010 [GO:0005643] nuclear pore; [PF13874] Nucleoporin complex subunit 54; [PTHR13000] NUCLEOPORIN P54; [KOG3091] Nuclear pore complex, p54 component (sc Nup57) 148.48 0.7130 186 Mapoly0063s0076 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF0] CELL DIVISION PROTEIN KINASE 7; [K02202] cyclin-dependent kinase 7 [EC:2.7.11.22]; [KOG0659] Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 149.10 0.6967 187 Mapoly0066s0041 [GO:0030915] Smc5-Smc6 complex; [PTHR21330] UNCHARACTERIZED; [GO:0019789] SUMO ligase activity; [PF11789] Zinc-finger of the MIZ type in Nse subunit; [GO:0000724] double-strand break repair via homologous recombination 150.40 0.6957 188 Mapoly0005s0111 [PF13414] TPR repeat; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR 150.57 0.6917 189 Mapoly0043s0034 [PTHR13233] MICROSPHERULE PROTEIN 1; [GO:0005515] protein binding; [PTHR13233:SF0] SUBFAMILY NOT NAMED; [PF13325] N-terminal region of micro-spherule protein; [PF00498] FHA domain 151.16 0.7269 190 Mapoly0015s0045 [KOG0533] RRM motif-containing protein; [PTHR19965] RNA AND EXPORT FACTOR BINDING PROTEIN; [K12881] THO complex subunit 4; [PF13865] C-terminal duplication domain of Friend of PRMT1; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 151.46 0.6978 191 Mapoly0024s0112 [GO:0005643] nuclear pore; [KOG1964] Nuclear pore complex, rNup107 component (sc Nup84); [PTHR13003] NUP107-RELATED; [GO:0006810] transport; [PF04121] Nuclear pore protein 84 / 107; [K14301] nuclear pore complex protein Nup107 152.21 0.7218 192 Mapoly0069s0083 [K11662] actin-related protein 6; [PF00022] Actin; [PTHR11937:SF21] ACTIN-LIKE PROTEIN; [PTHR11937] ACTIN; [KOG0680] Actin-related protein - Arp6p 152.37 0.6523 193 Mapoly0118s0038 - 152.48 0.7087 194 Mapoly0005s0056 [GO:0005524] ATP binding; [PTHR11752] HELICASE SKI2W; [KOG0947] Cytoplasmic exosomal RNA helicase SKI2, DEAD-box superfamily; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF08148] DSHCT (NUC185) domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [PF13234] rRNA-processing arch domain; [GO:0003676] nucleic acid binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [K12599] antiviral helicase SKI2 [EC:3.6.4.-] 153.57 0.7021 195 Mapoly0197s0019 [PTHR10751] GUANYLATE BINDING PROTEIN; [PTHR10751:SF2] GUANYLATE BINDING PROTEIN; [PF02263] Guanylate-binding protein, N-terminal domain; [GO:0003924] GTPase activity; [GO:0005525] GTP binding; [PF02841] Guanylate-binding protein, C-terminal domain 154.00 0.6778 196 Mapoly0074s0025 [PTHR12933] ORF PROTEIN-RELATED; [PF06862] Protein of unknown function (DUF1253); [KOG2340] Uncharacterized conserved protein; [GO:0005634] nucleus 154.48 0.6006 197 Mapoly0010s0012 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF06461] Domain of Unknown Function (DUF1086); [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00176] SNF2 family N-terminal domain; [PF06465] Domain of Unknown Function (DUF1087); [3.6.4.12] DNA helicase.; [PF00271] Helicase conserved C-terminal domain; [K11643] chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12]; [KOG0384] Chromodomain-helicase DNA-binding protein 156.92 0.7306 198 Mapoly0085s0079 [PF01426] BAH domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [GO:0003682] chromatin binding; [PTHR12505] PHD FINGER TRANSCRIPTION FACTOR 158.16 0.7280 199 Mapoly0069s0028 [3.1.27.-] Endoribonucleases producing other than 5'-phosphomonoesters.; [PF07521] RNA-metabolising metallo-beta-lactamase; [PTHR11203] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [PF11718] Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term; [KOG1137] mRNA cleavage and polyadenylation factor II complex, BRR5 (CPSF subunit); [PF00753] Metallo-beta-lactamase superfamily; [K14403] cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]; [PF10996] Beta-Casp domain; [PTHR11203:SF32] UNCHARACTERIZED 158.58 0.6591 200 Mapoly0061s0094 [GO:0005634] nucleus; [PTHR15217:SF0] SUBFAMILY NOT NAMED; [PTHR15217] WILMS' TUMOR 1-ASSOCIATING PROTEIN; [KOG2991] Splicing regulator; [GO:0048024] regulation of mRNA splicing, via spliceosome 159.19 0.7169