| 1 |
Mapoly0015s0052
| [KOG2467] Glycine/serine hydroxymethyltransferase; [GO:0006544] glycine metabolic process; [2.1.2.1] Glycine hydroxymethyltransferase.; [GO:0006563] L-serine metabolic process; [K00600] glycine hydroxymethyltransferase [EC:2.1.2.1]; [PF00464] Serine hydroxymethyltransferase; [GO:0004372] glycine hydroxymethyltransferase activity; [PTHR11680] SERINE HYDROXYMETHYLTRANSFERASE | 2.65 | 0.8027 |
| 2 |
Mapoly0031s0040
| [PF00206] Lyase; [4.3.2.2] Adenylosuccinate lyase.; [K01756] adenylosuccinate lyase [EC:4.3.2.2]; [KOG2700] Adenylosuccinate lyase; [PF08328] Adenylosuccinate lyase C-terminal; [GO:0004018] N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; [PTHR11444] ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE; [GO:0006188] IMP biosynthetic process | 7.55 | 0.7732 |
| 3 |
Mapoly0070s0045
| [PF00483] Nucleotidyl transferase; [K03241] translation initiation factor eIF-2B gamma subunit; [GO:0009058] biosynthetic process; [PTHR22572] SUGAR-1-PHOSPHATE GUANYL TRANSFERASE; [KOG1462] Translation initiation factor 2B, gamma subunit (eIF-2Bgamma/GCD1); [GO:0016779] nucleotidyltransferase activity; [PTHR22572:SF8] TRANSLATION INITIATION FACTOR EIF-2B GAMMA SUBUNIT | 8.66 | 0.7121 |
| 4 |
Mapoly0032s0021
| [KOG2555] AICAR transformylase/IMP cyclohydrolase/methylglyoxal synthase; [PF01808] AICARFT/IMPCHase bienzyme; [PTHR11692] BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN; [GO:0003937] IMP cyclohydrolase activity; [PF02142] MGS-like domain; [GO:0004643] phosphoribosylaminoimidazolecarboxamide formyltransferase activity; [3.5.4.10] IMP cyclohydrolase.; [GO:0006164] purine nucleotide biosynthetic process; [2.1.2.3] Phosphoribosylaminoimidazolecarboxamide formyltransferase.; [K00602] phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] | 10.00 | 0.7617 |
| 5 |
Mapoly0041s0149
| [GO:0009113] purine nucleobase biosynthetic process; [PF02844] Phosphoribosylglycinamide synthetase, N domain; [PTHR10520] TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED; [PF01071] Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; [GO:0004637] phosphoribosylamine-glycine ligase activity; [K01945] phosphoribosylamine--glycine ligase [EC:6.3.4.13]; [PF02843] Phosphoribosylglycinamide synthetase, C domain; [6.3.4.13] Phosphoribosylamine--glycine ligase. | 12.33 | 0.7785 |
| 6 |
Mapoly0084s0006
| [PF08245] Mur ligase middle domain; [GO:0005524] ATP binding; [GO:0009396] folic acid-containing compound biosynthetic process; [PTHR11136] FOLYLPOLYGLUTAMATE SYNTHASE-RELATED; [GO:0009058] biosynthetic process; [6.3.2.17] Tetrahydrofolate synthase.; [KOG2525] Folylpolyglutamate synthase; [K01930] folylpolyglutamate synthase [EC:6.3.2.17]; [GO:0004326] tetrahydrofolylpolyglutamate synthase activity; [PTHR11136:SF0] SUBFAMILY NOT NAMED | 13.93 | 0.6355 |
| 7 |
Mapoly0046s0034
| [4.1.1.21] Phosphoribosylaminoimidazole carboxylase.; [PTHR23047:SF1] PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE ATPASE-SUBUNIT; [PTHR23047] PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE ATPASE-SUBUNIT; [KOG2835] Phosphoribosylamidoimidazole-succinocarboxamide synthase; [K11808] phosphoribosylaminoimidazole carboxylase [EC:4.1.1.21]; [PF02222] ATP-grasp domain; [GO:0006189] 'de novo' IMP biosynthetic process; [PF00731] AIR carboxylase | 14.87 | 0.7226 |
| 8 |
Mapoly0013s0023
| [GO:0000287] magnesium ion binding; [GO:0003723] RNA binding; [GO:0005524] ATP binding; [PF03483] B3/4 domain; [GO:0005737] cytoplasm; [K01890] phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]; [GO:0004826] phenylalanine-tRNA ligase activity; [PF03484] tRNA synthetase B5 domain; [6.1.1.20] Phenylalanine--tRNA ligase.; [GO:0043039] tRNA aminoacylation; [GO:0006432] phenylalanyl-tRNA aminoacylation; [GO:0000049] tRNA binding; [KOG2472] Phenylalanyl-tRNA synthetase beta subunit; [GO:0004812] aminoacyl-tRNA ligase activity; [PTHR10947] PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47; [PF01409] tRNA synthetases class II core domain (F) | 15.10 | 0.7592 |
| 9 |
Mapoly0102s0045
| [PF00571] CBS domain; [K00088] IMP dehydrogenase [EC:1.1.1.205]; [GO:0055114] oxidation-reduction process; [PTHR11911:SF6] INOSINE-5-MONOPHOSPHATE DEHYDROGENASE; [PTHR11911] INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; [PF00478] IMP dehydrogenase / GMP reductase domain; [1.1.1.205] IMP dehydrogenase.; [GO:0003824] catalytic activity; [GO:0030554] adenyl nucleotide binding; [GO:0006164] purine nucleotide biosynthetic process; [KOG2550] IMP dehydrogenase/GMP reductase; [GO:0003938] IMP dehydrogenase activity | 15.10 | 0.7640 |
| 10 |
Mapoly0022s0124
| - | 19.34 | 0.7261 |
| 11 |
Mapoly0012s0185
| [GO:0055114] oxidation-reduction process; [GO:0009396] folic acid-containing compound biosynthetic process; [GO:0004488] methylenetetrahydrofolate dehydrogenase (NADP+) activity; [PTHR10025] TETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE FAMILY MEMBER; [PF02882] Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; [PF00763] Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; [GO:0003824] catalytic activity; [KOG0089] Methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase | 20.25 | 0.7277 |
| 12 |
Mapoly0118s0031
| [PTHR13068:SF8] gb def: riken cdna 2410017i18 [mus musculus]; [KOG1267] Mitochondrial transcription termination factor, mTERF; [PF02536] mTERF; [PTHR13068] CGI-12 PROTEIN-RELATED | 23.07 | 0.7468 |
| 13 |
Mapoly0052s0107
| [GO:0009116] nucleoside metabolic process; [PF00215] Orotidine 5'-phosphate decarboxylase / HUMPS family; [KOG1377] Uridine 5'- monophosphate synthase/orotate phosphoribosyltransferase; [K13421] uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23]; [PTHR19278] FAMILY NOT NAMED; [4.1.1.23] Orotidine-5'-phosphate decarboxylase.; [GO:0004590] orotidine-5'-phosphate decarboxylase activity; [PTHR19278:SF9] SUBFAMILY NOT NAMED; [2.4.2.10] Orotate phosphoribosyltransferase.; [PF00156] Phosphoribosyl transferase domain; [GO:0006207] 'de novo' pyrimidine nucleobase biosynthetic process | 28.34 | 0.6501 |
| 14 |
Mapoly0005s0193
| [PF00206] Lyase; [PF14698] Argininosuccinate lyase C-terminal; [4.3.2.1] Argininosuccinate lyase.; [KOG1316] Argininosuccinate lyase; [GO:0004056] argininosuccinate lyase activity; [PTHR11444:SF3] ARGININOSUCCINATE LYASE; [PTHR11444] ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE; [GO:0042450] arginine biosynthetic process via ornithine; [K01755] argininosuccinate lyase [EC:4.3.2.1] | 32.37 | 0.7413 |
| 15 |
Mapoly0067s0028
| [GO:0051087] chaperone binding; [PTHR21237] GRPE PROTEIN; [PF01025] GrpE; [GO:0006457] protein folding; [GO:0042803] protein homodimerization activity; [K03687] molecular chaperone GrpE; [KOG3003] Molecular chaperone of the GrpE family; [GO:0000774] adenyl-nucleotide exchange factor activity | 32.76 | 0.6905 |
| 16 |
Mapoly0173s0025
| [PF12452] Protein of unknown function (DUF3685) | 36.33 | 0.7012 |
| 17 |
Mapoly0173s0009
| [GO:0005524] ATP binding; [K00872] homoserine kinase [EC:2.7.1.39]; [PTHR20861] HOMOSERINE/4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE; [PTHR20861:SF1] HOMOSERINE KINASE; [PF08544] GHMP kinases C terminal; [2.7.1.39] Homoserine kinase.; [PF00288] GHMP kinases N terminal domain; [KOG1537] Homoserine kinase | 36.95 | 0.6791 |
| 18 |
Mapoly0002s0326
| [GO:0003922] GMP synthase (glutamine-hydrolyzing) activity; [GO:0005524] ATP binding; [PF00958] GMP synthase C terminal domain; [6.3.5.2] GMP synthase (glutamine-hydrolyzing).; [KOG1622] GMP synthase; [PTHR11922] GMP SYNTHASE-RELATED; [GO:0006177] GMP biosynthetic process; [K01951] GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]; [PF00117] Glutamine amidotransferase class-I; [GO:0006164] purine nucleotide biosynthetic process | 37.47 | 0.7404 |
| 19 |
Mapoly0028s0095
| [GO:0005744] mitochondrial inner membrane presequence translocase complex; [PTHR10485] MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17; [PTHR10485:SF0] MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17; [KOG1652] Mitochondrial import inner membrane translocase, subunit TIM17; [GO:0006886] intracellular protein transport; [PF02466] Tim17/Tim22/Tim23/Pmp24 family; [GO:0015450] P-P-bond-hydrolysis-driven protein transmembrane transporter activity | 37.56 | 0.7037 |
| 20 |
Mapoly0168s0006
| [KOG4836] Uncharacterized conserved protein; [GO:0005744] mitochondrial inner membrane presequence translocase complex; [PF08294] TIM21; [PTHR13032] FAMILY NOT NAMED; [GO:0030150] protein import into mitochondrial matrix | 40.95 | 0.6720 |
| 21 |
Mapoly0007s0098
| [GO:0005524] ATP binding; [KOG0742] AAA+-type ATPase; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23075] PUTATIVE ATP-ASE; [PF12037] Domain of unknown function (DUF3523) | 44.63 | 0.7250 |
| 22 |
Mapoly0003s0273
| [PF02769] AIR synthase related protein, C-terminal domain; [PTHR10520] TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED; [6.3.3.1] Phosphoribosylformylglycinamidine cyclo-ligase.; [K01933] phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]; [PF00586] AIR synthase related protein, N-terminal domain; [GO:0003824] catalytic activity; [PTHR10520:SF22] PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE | 45.89 | 0.7036 |
| 23 |
Mapoly0006s0284
| [PTHR23417] 3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE; [PF02390] Putative methyltransferase; [GO:0008176] tRNA (guanine-N7-)-methyltransferase activity; [KOG3115] Methyltransferase-like protein; [GO:0006400] tRNA modification | 51.38 | 0.6530 |
| 24 |
Mapoly0006s0044
| [K00565] mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]; [PTHR12189] MRNA (GUANINE-7-)METHYLTRANSFERASE; [KOG1975] mRNA cap methyltransferase; [2.1.1.56] mRNA (guanine-N(7)-)-methyltransferase.; [PF03291] mRNA capping enzyme | 51.67 | 0.5081 |
| 25 |
Mapoly0008s0155
| [6.3.5.5] Carbamoyl-phosphate synthase (glutamine-hydrolyzing).; [PF00988] Carbamoyl-phosphate synthase small chain, CPSase domain; [PTHR11405] CARBAMOYLTRANSFERASE RELATED; [KOG0026] Anthranilate synthase, beta chain; [PF00117] Glutamine amidotransferase class-I; [K01956] carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] | 53.96 | 0.6628 |
| 26 |
Mapoly0045s0011
| [GO:0005524] ATP binding; [6.1.1.10] Methionine--tRNA ligase.; [GO:0000166] nucleotide binding; [PF01588] Putative tRNA binding domain; [PTHR11946] ISOLEUCYL, LEUCYL, TYROSYL, VALYL AND METHIONYL-TRNA SYNTHETASES; [GO:0000049] tRNA binding; [PF09334] tRNA synthetases class I (M); [GO:0006418] tRNA aminoacylation for protein translation; [GO:0004812] aminoacyl-tRNA ligase activity; [K01874] methionyl-tRNA synthetase [EC:6.1.1.10]; [KOG1247] Methionyl-tRNA synthetase | 54.41 | 0.7030 |
| 27 |
Mapoly0053s0020
| [GO:0004830] tryptophan-tRNA ligase activity; [6.1.1.2] Tryptophan--tRNA ligase.; [GO:0005524] ATP binding; [KOG2145] Cytoplasmic tryptophanyl-tRNA synthetase; [PF00579] tRNA synthetases class I (W and Y); [GO:0005737] cytoplasm; [GO:0000166] nucleotide binding; [K01867] tryptophanyl-tRNA synthetase [EC:6.1.1.2]; [PTHR10055:SF1] TRYPTOPHANYL-TRNA SYNTHETASE, CYTOPLASMIC; [GO:0006418] tRNA aminoacylation for protein translation; [GO:0006436] tryptophanyl-tRNA aminoacylation; [PTHR10055] TRYPTOPHANYL-TRNA SYNTHETASE; [GO:0004812] aminoacyl-tRNA ligase activity | 54.89 | 0.7002 |
| 28 |
Mapoly0010s0155
| [PF08213] Mitochondrial domain of unknown function (DUF1713) | 56.87 | 0.6819 |
| 29 |
Mapoly0004s0145
| [PTHR24012] FAMILY NOT NAMED; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) | 57.97 | 0.7180 |
| 30 |
Mapoly0005s0066
| [PTHR22749] RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE; [GO:0009231] riboflavin biosynthetic process; [GO:0008531] riboflavin kinase activity; [PF01687] Riboflavin kinase; [PTHR22749:SF1] RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE; [2.7.1.26] Riboflavin kinase.; [PF13419] Haloacid dehalogenase-like hydrolase; [K00861] riboflavin kinase [EC:2.7.1.26]; [KOG3110] Riboflavin kinase | 61.79 | 0.6445 |
| 31 |
Mapoly0007s0029
| [KOG3165] Predicted nucleic-acid-binding protein, contains PIN domain; [PF04900] Fcf1; [PTHR12416] UNCHARACTERIZED; [GO:0032040] small-subunit processome; [K14566] U3 small nucleolar RNA-associated protein 24 | 62.21 | 0.6902 |
| 32 |
Mapoly0023s0019
| [PF12710] haloacid dehalogenase-like hydrolase; [KOG1615] Phosphoserine phosphatase; [PTHR10000] PHOSPHOSERINE PHOSPHATASE; [3.1.3.3] Phosphoserine phosphatase.; [K01079] phosphoserine phosphatase [EC:3.1.3.3] | 62.58 | 0.6694 |
| 33 |
Mapoly0003s0096
| [PTHR13271] UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE; [GO:0005515] protein binding; [PF00856] SET domain; [PF09273] Rubisco LSMT substrate-binding | 63.89 | 0.6969 |
| 34 |
Mapoly0031s0031
| [GO:0005840] ribosome; [PF00861] Ribosomal L18p/L5e family; [GO:0003735] structural constituent of ribosome; [GO:0005622] intracellular; [PTHR12899] 39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL; [GO:0006412] translation | 67.46 | 0.6713 |
| 35 |
Mapoly0011s0087
| - | 67.97 | 0.6443 |
| 36 |
Mapoly0027s0074
| [PTHR23111] ZINC FINGER PROTEIN; [GO:0008270] zinc ion binding; [PF00641] Zn-finger in Ran binding protein and others; [KOG4198] RNA-binding Ran Zn-finger protein and related proteins | 68.59 | 0.7025 |
| 37 |
Mapoly0066s0007
| [PF00291] Pyridoxal-phosphate dependent enzyme; [KOG1252] Cystathionine beta-synthase and related enzymes; [PTHR10314] SER/THR DEHYDRATASE, TRP SYNTHASE | 69.07 | 0.6620 |
| 38 |
Mapoly0144s0025
| [GO:0005524] ATP binding; [K04077] chaperonin GroEL; [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family; [KOG0356] Mitochondrial chaperonin, Cpn60/Hsp60p | 71.25 | 0.6945 |
| 39 |
Mapoly0029s0132
| [K02355] elongation factor EF-G [EC:3.6.5.3]; [PF14492] Elongation Factor G, domain II; [3.6.5.3] Protein-synthesizing GTPase.; [PF00009] Elongation factor Tu GTP binding domain; [KOG0465] Mitochondrial elongation factor; [PF00679] Elongation factor G C-terminus; [GO:0003924] GTPase activity; [PTHR23115:SF66] SUBFAMILY NOT NAMED; [PTHR23115] TRANSLATION FACTOR; [PF03764] Elongation factor G, domain IV; [GO:0005525] GTP binding; [PF03144] Elongation factor Tu domain 2 | 75.30 | 0.6545 |
| 40 |
Mapoly0003s0283
| [PF00135] Carboxylesterase family; [PTHR23024] MEMBER OF 'GDXG' FAMILY OF LIPOLYTIC ENZYMES | 76.84 | 0.5983 |
| 41 |
Mapoly0070s0010
| [PTHR10721] MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44; [PF04280] Tim44-like domain; [KOG2580] Mitochondrial import inner membrane translocase, subunit TIM44 | 78.69 | 0.6666 |
| 42 |
Mapoly0093s0033
| [PTHR22939] SERINE PROTEASE FAMILY S1C HTRA-RELATED; [GO:0005515] protein binding; [PF13180] PDZ domain; [KOG1320] Serine protease; [PTHR22939:SF1] SERINE ENDOPEPTIDASE DEGP2; [PF13365] Trypsin-like peptidase domain | 80.00 | 0.7066 |
| 43 |
Mapoly0157s0006
| [PTHR26312] FAMILY NOT NAMED; [GO:0005515] protein binding; [PF13432] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat | 80.50 | 0.6682 |
| 44 |
Mapoly0007s0267
| - | 81.12 | 0.6373 |
| 45 |
Mapoly0051s0055
| [PTHR18359] WD-REPEAT PROTEIN-RELATED; [GO:0005515] protein binding; [KOG2055] WD40 repeat protein; [K14553] U3 small nucleolar RNA-associated protein 18; [PF00400] WD domain, G-beta repeat | 82.36 | 0.7035 |
| 46 |
Mapoly0032s0093
| [PF02096] 60Kd inner membrane protein; [KOG1239] Inner membrane protein translocase involved in respiratory chain assembly; [K03217] preprotein translocase subunit YidC; [GO:0016021] integral to membrane; [PTHR12428] OXA1; [GO:0051205] protein insertion into membrane | 82.73 | 0.6571 |
| 47 |
Mapoly0132s0010
| [GO:0005524] ATP binding; [K01876] aspartyl-tRNA synthetase [EC:6.1.1.12]; [GO:0004815] aspartate-tRNA ligase activity; [GO:0005737] cytoplasm; [GO:0006422] aspartyl-tRNA aminoacylation; [6.1.1.12] Aspartate--tRNA ligase.; [GO:0000166] nucleotide binding; [PTHR22594] ASPARTYL/LYSYL-TRNA SYNTHETASE; [GO:0003676] nucleic acid binding; [KOG0556] Aspartyl-tRNA synthetase; [PTHR22594:SF10] SUBFAMILY NOT NAMED; [PF01336] OB-fold nucleic acid binding domain; [GO:0006418] tRNA aminoacylation for protein translation; [GO:0004812] aminoacyl-tRNA ligase activity; [PF00152] tRNA synthetases class II (D, K and N) | 83.67 | 0.6716 |
| 48 |
Mapoly0037s0138
| [KOG2061] Uncharacterized MYND Zn-finger protein; [PF04194] Programmed cell death protein 2, C-terminal putative domain; [GO:0005737] cytoplasm; [PTHR12298] PCDC2 (PROGRAMMED CELL DEATH PROTEIN 2)-RELATED; [PF01753] MYND finger | 83.90 | 0.6425 |
| 49 |
Mapoly0041s0125
| [GO:0016020] membrane; [PF01554] MatE; [GO:0015238] drug transmembrane transporter activity; [GO:0015297] antiporter activity; [GO:0055085] transmembrane transport; [PTHR11206] MULTIDRUG RESISTANCE PROTEIN; [KOG1347] Uncharacterized membrane protein, predicted efflux pump; [GO:0006855] drug transmembrane transport | 84.14 | 0.5708 |
| 50 |
Mapoly0079s0015
| [PTHR11778] SERYL-TRNA SYNTHETASE; [GO:0005524] ATP binding; [GO:0004828] serine-tRNA ligase activity; [K01875] seryl-tRNA synthetase [EC:6.1.1.11]; [GO:0005737] cytoplasm; [GO:0006434] seryl-tRNA aminoacylation; [PF00587] tRNA synthetase class II core domain (G, H, P, S and T); [KOG2509] Seryl-tRNA synthetase; [PF02403] Seryl-tRNA synthetase N-terminal domain; [GO:0000166] nucleotide binding; [PTHR11778:SF0] SUBFAMILY NOT NAMED; [6.1.1.11] Serine--tRNA ligase.; [GO:0006418] tRNA aminoacylation for protein translation; [GO:0004812] aminoacyl-tRNA ligase activity | 85.06 | 0.6755 |
