Guide Gene
- Gene ID
- Mapoly0028s0103
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [PF01713] Smr domain; [GO:0003677] DNA binding; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K07456] DNA mismatch repair protein MutS2; [GO:0016887] ATPase activity; [PTHR11361:SF14] DNA MISMATCH REPAIR PROTEIN MUTS2; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [GO:0045910] negative regulation of DNA recombination
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0028s0103 [PF01713] Smr domain; [GO:0003677] DNA binding; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K07456] DNA mismatch repair protein MutS2; [GO:0016887] ATPase activity; [PTHR11361:SF14] DNA MISMATCH REPAIR PROTEIN MUTS2; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [GO:0045910] negative regulation of DNA recombination 0.00 1.0000 1 Mapoly0058s0047 [PF00091] Tubulin/FtsZ family, GTPase domain; [PTHR23084] PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED; [PF02493] MORN repeat 4.24 0.6704 2 Mapoly0063s0041 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PTHR23340] ARGININE/SERINE RICH SPLICING FACTOR SF4/14; [PF01585] G-patch domain; [GO:0003676] nucleic acid binding; [PF01805] Surp module 11.58 0.6997 3 Mapoly0060s0008 [PF07748] Glycosyl hydrolases family 38 C-terminal domain; [GO:0015923] mannosidase activity; [PTHR11607] ALPHA-MANNOSIDASE; [GO:0004559] alpha-mannosidase activity; [GO:0006013] mannose metabolic process; [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [PF09261] Alpha mannosidase, middle domain; [GO:0005975] carbohydrate metabolic process; [GO:0008270] zinc ion binding; [K01231] alpha-mannosidase II [EC:3.2.1.114]; [PF01074] Glycosyl hydrolases family 38 N-terminal domain; [PTHR11607:SF4] MANNOSIDASE ALPHA CLASS 2A; [3.2.1.114] Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase.; [KOG1958] Glycosyl hydrolase, family 38 - alpha-mannosidase 12.33 0.6747 4 Mapoly0035s0057 [PF03109] ABC1 family; [PTHR10566] CHAPERONE-ACTIVITY OF BC1 COMPLEX (CABC1)-RELATED; [KOG1235] Predicted unusual protein kinase; [K08869] aarF domain-containing kinase 13.96 0.6416 5 Mapoly0002s0238 [GO:0003847] 1-alkyl-2-acetylglycerophosphocholine esterase activity; [GO:0016042] lipid catabolic process; [3.1.1.47] 1-alkyl-2-acetylglycerophosphocholine esterase.; [K01062] 1-alkyl-2-acetylglycerophosphocholine esterase [EC:3.1.1.47]; [PTHR10272] PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE; [PF03403] Platelet-activating factor acetylhydrolase, isoform II; [KOG3847] Phospholipase A2 (platelet-activating factor acetylhydrolase in humans) 16.28 0.6042 6 Mapoly0006s0149 [KOG4732] Uncharacterized conserved protein; [PTHR21483] FAMILY NOT NAMED; [PF08620] RPAP1-like, C-terminal; [PF08621] RPAP1-like, N-terminal 16.49 0.6394 7 Mapoly0224s0007 [PTHR12456] TOPOISOMERASE 1-BINDING RING FINGER-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [GO:0046872] metal ion binding 22.14 0.6636 8 Mapoly0084s0045 [PF07719] Tetratricopeptide repeat; [KOG1211] Amidases; [PF13414] TPR repeat; [PTHR11895] AMIDASE; [GO:0016884] carbon-nitrogen ligase activity, with glutamine as amido-N-donor; [PTHR11895:SF6] AMIDASE; [PF01425] Amidase 23.02 0.6667 9 Mapoly0091s0053 [KOG0963] Transcription factor/CCAAT displacement protein CDP1; [PTHR14043] CCAAT DISPLACEMENT PROTEIN-RELATED; [K09313] homeobox protein cut-like; [GO:0006891] intra-Golgi vesicle-mediated transport; [GO:0030173] integral to Golgi membrane; [PF08172] CASP C terminal 27.46 0.6432 10 Mapoly0132s0046 [PF00855] PWWP domain; [PTHR12550] HEPATOMA-DERIVED GROWTH FACTOR-RELATED; [PTHR12550:SF5] UNCHARACTERIZED 33.32 0.6638 11 Mapoly0004s0169 [GO:0003677] DNA binding; [GO:0006338] chromatin remodeling; [GO:0005524] ATP binding; [PF09110] HAND; [K11654] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]; [GO:0043044] ATP-dependent chromatin remodeling; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [GO:0005634] nucleus; [PTHR10799:SF73] ISWI CHROMATIN-REMODELING COMPLEX ATPASE ISW1; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [KOG0385] Chromatin remodeling complex WSTF-ISWI, small subunit; [GO:0003676] nucleic acid binding; [GO:0031491] nucleosome binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [PF09111] SLIDE 39.24 0.6680 12 Mapoly0010s0073 [GO:0004518] nuclease activity; [PF04231] Endonuclease I 41.57 0.5608 13 Mapoly0044s0074 - 47.96 0.6333 14 Mapoly0008s0250 [PTHR24007] BRCA1-ASSOCIATED PROTEIN; [PF00917] MATH domain; [GO:0005515] protein binding; [GO:0006281] DNA repair; [PF14631] Fanconi anaemia protein FancD2 nuclease; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 50.56 0.6525 15 Mapoly0014s0006 [PTHR24089] FAMILY NOT NAMED; [PF00153] Mitochondrial carrier protein; [KOG0752] Mitochondrial solute carrier protein 51.17 0.5564 16 Mapoly0065s0001 - 52.00 0.5507 17 Mapoly0044s0136 [PF12171] Zinc-finger double-stranded RNA-binding; [K13104] zinc finger protein 830; [PTHR13278] UNCHARACTERIZED; [KOG3032] Uncharacterized conserved protein 52.31 0.6075 18 Mapoly0074s0043 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [GO:0003729] mRNA binding 53.89 0.6547 19 Mapoly0015s0206 [PF05236] Transcription initiation factor TFIID component TAF4 family; [GO:0006352] DNA-dependent transcription, initiation; [PTHR15138] FAMILY NOT NAMED; [PF12174] RCD1-SRO-TAF4 (RST) plant domain; [GO:0005669] transcription factor TFIID complex 54.50 0.6476 20 Mapoly0064s0101 [K10571] de-etiolated-1; [PTHR13374] DET1 HOMOLOG (DE-ETIOLATED-1 HOMOLOG); [PF09737] De-etiolated protein 1 Det1; [KOG2558] Negative regulator of histones 54.92 0.5303 21 Mapoly0112s0032 [KOG2652] RNA polymerase II transcription initiation factor TFIIA, large chain; [PTHR12694] TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; [PTHR12694:SF8] TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; [PF03153] Transcription factor IIA, alpha/beta subunit; [GO:0005672] transcription factor TFIIA complex; [K03122] transcription initiation factor TFIIA large subunit; [GO:0006367] transcription initiation from RNA polymerase II promoter 56.57 0.6363 22 Mapoly0014s0121 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0390] DNA repair protein, SNF2 family; [PF00271] Helicase conserved C-terminal domain 56.87 0.6419 23 Mapoly0007s0100 [PTHR15828] CYTOKINE RECEPTOR-LIKE FACTOR 3 65.45 0.6475 24 Mapoly0036s0123 [GO:0000922] spindle pole; [PTHR19302:SF13] GAMMA-TUBULIN COMPLEX COMPONENT 2 (GCP-2); [PF04130] Spc97 / Spc98 family; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [KOG2001] Gamma-tubulin complex, DGRIP84/SPC97 component 66.86 0.6521 25 Mapoly0095s0046 [PF13919] Asx homology domain; [GO:0006355] regulation of transcription, DNA-dependent; [PTHR10071] TRANSCRIPTION FACTOR GATA (GATA BINDING FACTOR); [GO:0043565] sequence-specific DNA binding; [GO:0008270] zinc ion binding; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF00320] GATA zinc finger 67.31 0.6240 26 Mapoly0021s0042 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [KOG0298] DEAD box-containing helicase-like transcription factor/DNA repair protein; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [PF00271] Helicase conserved C-terminal domain 73.85 0.6382 27 Mapoly0103s0005 [PTHR32059] FAMILY NOT NAMED; [GO:0005515] protein binding; [PTHR32059:SF0] SUBFAMILY NOT NAMED; [PF02985] HEAT repeat; [KOG0211] Protein phosphatase 2A regulatory subunit A and related proteins 74.83 0.6274 28 Mapoly0122s0048 - 75.97 0.5892 29 Mapoly0005s0067 [PTHR15242:SF0] SUBFAMILY NOT NAMED; [PTHR15242] SPLICING FACTOR, ARGININE/SERINE-RICH 2,RNAP C-TERM INTERACTING PROTEIN; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 76.94 0.6411 30 Mapoly0104s0019 [KOG2242] Scaffold/matrix specific factor hnRNP-U/SAF-A, contains SPRY domain; [PTHR12381:SF13] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [PF13671] AAA domain; [PF00622] SPRY domain; [PTHR12381] RIBONUCLEOPROTEIN 77.09 0.6347 31 Mapoly0091s0014 [PTHR12596:SF1] GB DEF: T27C4.14 PROTEIN; [PTHR12596] EXPORTIN 4,7-RELATED; [KOG4541] Nuclear transport receptor exportin 4 (importin beta superfamily) 77.36 0.6367 32 Mapoly0039s0001 - 80.42 0.6339 33 Mapoly0075s0086 - 84.12 0.6247 34 Mapoly0140s0030 [PF00773] RNB domain; [PTHR23355] RIBONUCLEASE; [KOG2102] Exosomal 3'-5' exoribonuclease complex, subunit Rrp44/Dis3 87.22 0.6332 35 Mapoly0033s0129 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0003910] DNA ligase (ATP) activity; [PF04679] ATP dependent DNA ligase C terminal region; [PTHR10459] DNA LIGASE; [K10747] DNA ligase 1 [EC:6.5.1.1]; [PF01068] ATP dependent DNA ligase domain; [6.5.1.1] DNA ligase (ATP).; [GO:0006281] DNA repair; [PF04675] DNA ligase N terminus; [PTHR10459:SF10] DNA LIGASE I; [GO:0006310] DNA recombination; [KOG0967] ATP-dependent DNA ligase I 87.27 0.6223 36 Mapoly0197s0017 [PTHR10751] GUANYLATE BINDING PROTEIN; [KOG1003] Actin filament-coating protein tropomyosin; [PTHR10751:SF2] GUANYLATE BINDING PROTEIN; [PF02263] Guanylate-binding protein, N-terminal domain; [GO:0003924] GTPase activity; [GO:0005525] GTP binding; [PF02841] Guanylate-binding protein, C-terminal domain 87.35 0.6212 37 Mapoly0119s0035 - 90.33 0.6218 38 Mapoly0045s0096 [K08775] breast cancer 2 susceptibility protein; [PTHR11289] BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2; [GO:0003697] single-stranded DNA binding; [PF09169] BRCA2, helical; [PTHR11289:SF0] SUBFAMILY NOT NAMED; [GO:0006281] DNA repair; [PF09103] BRCA2, oligonucleotide/oligosaccharide-binding, domain 1; [GO:0000724] double-strand break repair via homologous recombination; [GO:0006310] DNA recombination 94.97 0.6022 39 Mapoly0001s0073 [PF13964] Kelch motif; [PTHR24412] FAMILY NOT NAMED; [PF01344] Kelch motif; [GO:0005515] protein binding 99.00 0.5102 40 Mapoly0054s0103 [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [3.6.4.13] RNA helicase.; [KOG0923] mRNA splicing factor ATP-dependent RNA helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [PF07717] Oligonucleotide/oligosaccharide-binding (OB)-fold; [K12813] pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:3.6.4.13] 99.00 0.6277 41 Mapoly0108s0010 [PF04424] Protein of unknown function (DUF544); [PTHR18063] NF-E2 INDUCIBLE PROTEIN 100.21 0.5700 42 Mapoly0063s0006 [KOG2217] U4/U6.U5 snRNP associated protein; [K11984] U4/U6.U5 tri-snRNP-associated protein 1; [PTHR14152:SF5] SUBFAMILY NOT NAMED; [PTHR14152] SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES; [PF03343] SART-1 family 101.37 0.6302 43 Mapoly0011s0137 [K03504] DNA polymerase delta subunit 3; [GO:0006260] DNA replication; [PTHR17598] FAMILY NOT NAMED; [PF09507] DNA polymerase subunit Cdc27; [GO:0005634] nucleus 101.73 0.6289 44 Mapoly0001s0490 [PTHR21512:SF5] GB DEF: HYPOTHETICAL PROTEIN T5K6_30; [PTHR21512] FAMILY NOT NAMED; [KOG1953] Targeting complex (TRAPP) subunit; [PF08626] Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit 104.30 0.6187 45 Mapoly0135s0035 [GO:0003676] nucleic acid binding; [PF02037] SAP domain 107.78 0.6222 46 Mapoly0143s0017 - 108.44 0.6005 47 Mapoly0162s0013 [PF00929] Exonuclease; [PF00488] MutS domain V; [GO:0005524] ATP binding; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [PTHR11361:SF34] DNA MISMATCH REPAIR PROTEIN MUTS; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [KOG0218] Mismatch repair MSH3; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 112.33 0.6229 48 Mapoly0003s0184 [GO:0006396] RNA processing; [GO:0003677] DNA binding; [GO:0003723] RNA binding; [GO:0005524] ATP binding; [K11592] endoribonuclease Dicer [EC:3.1.26.-]; [PF02170] PAZ domain; [3.1.26.-] Endoribonucleases producing 5'-phosphomonoesters.; [PTHR14950] HELICASE-RELATED; [GO:0005515] protein binding; [GO:0016891] endoribonuclease activity, producing 5'-phosphomonoesters; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [PF03368] Dicer dimerisation domain; [PF00636] Ribonuclease III domain; [GO:0004525] ribonuclease III activity; [PF00271] Helicase conserved C-terminal domain; [PF14709] double strand RNA binding domain from DEAD END PROTEIN 1; [KOG0701] dsRNA-specific nuclease Dicer and related ribonucleases 112.83 0.6175 49 Mapoly0039s0120 [KOG1805] DNA replication helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PTHR10887:SF14] DNA2-LIKE HELICASE; [3.6.4.12] DNA helicase.; [PF13086] AAA domain; [GO:0033567] DNA replication, Okazaki fragment processing; [PF01930] Domain of unknown function DUF83; [GO:0017108] 5'-flap endonuclease activity; [GO:0043142] single-stranded DNA-dependent ATPase activity; [PF13087] AAA domain; [PF08696] DNA replication factor Dna2; [K10742] DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12] 114.00 0.6134 50 Mapoly0122s0032 [PF14695] Lines C-terminus 114.17 0.5803 51 Mapoly0011s0008 [PTHR11254] HECT DOMAIN UBIQUITIN-PROTEIN LIGASE; [KOG0941] E3 ubiquitin protein ligase; [GO:0004842] ubiquitin-protein ligase activity; [PF00415] Regulator of chromosome condensation (RCC1) repeat; [PF00632] HECT-domain (ubiquitin-transferase) 116.79 0.5993 52 Mapoly0091s0060 - 123.42 0.6018 53 Mapoly0067s0015 [PTHR13271] UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE; [GO:0005515] protein binding; [PF00856] SET domain; [PF09273] Rubisco LSMT substrate-binding 123.49 0.5944 54 Mapoly0065s0047 [PF13837] Myb/SANT-like DNA-binding domain 124.10 0.6115 55 Mapoly0033s0156 [KOG0266] WD40 repeat-containing protein; [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [PF00400] WD domain, G-beta repeat 124.51 0.6088 56 Mapoly0021s0077 [GO:0005685] U1 snRNP; [GO:0006376] mRNA splice site selection; [PF03194] LUC7 N_terminus; [PTHR12375] RNA-BINDING PROTEIN LUC7-RELATED; [KOG0796] Spliceosome subunit; [GO:0003729] mRNA binding 127.70 0.6201 57 Mapoly0007s0195 [GO:0006904] vesicle docking involved in exocytosis; [GO:0016192] vesicle-mediated transport; [PTHR11679] VESICLE PROTEIN SORTING-ASSOCIATED; [KOG1301] Vesicle trafficking protein Sly1 (Sec1 family); [PTHR11679:SF2] SLY1-RELATED; [PF00995] Sec1 family 128.12 0.5818 58 Mapoly0001s0238 [PF02978] Signal peptide binding domain; [GO:0048500] signal recognition particle; [PF00448] SRP54-type protein, GTPase domain; [GO:0008312] 7S RNA binding; [K03106] signal recognition particle subunit SRP54; [KOG0780] Signal recognition particle, subunit Srp54; [GO:0006614] SRP-dependent cotranslational protein targeting to membrane; [PF02881] SRP54-type protein, helical bundle domain; [GO:0005525] GTP binding; [PTHR11564:SF5] SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN; [PTHR11564] GTPASE CONTAINING FAMILY OF SIGNAL RECOGNITION PARTICLE PROTEINS 128.37 0.5892 59 Mapoly0010s0094 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [PF00454] Phosphatidylinositol 3- and 4-kinase; [KOG0889] Histone acetyltransferase SAGA, TRRAP/TRA1 component, PI-3 kinase superfamily; [PTHR11139:SF1] ATM-RELATED; [K08874] transformation/transcription domain-associated protein; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED 128.97 0.6125 60 Mapoly0177s0009 [KOG2641] Predicted seven transmembrane receptor - rhodopsin family; [PTHR23423] ORGANIC SOLUTE TRANSPORTER-RELATED; [PF03619] Organic solute transporter Ostalpha 132.78 0.5400 61 Mapoly0100s0038 [GO:0007264] small GTPase mediated signal transduction; [PTHR24073] FAMILY NOT NAMED; [KOG0098] GTPase Rab2, small G protein superfamily; [PF15305] Intraflagellar transport protein 43; [PF00071] Ras family; [GO:0005525] GTP binding; [GO:0030991] intraflagellar transport particle A 134.18 0.5967 62 Mapoly0099s0053 [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0046872] metal ion binding 135.50 0.6158 63 Mapoly0015s0164 [GO:0003677] DNA binding; [PF02362] B3 DNA binding domain; [PTHR31391] FAMILY NOT NAMED 135.50 0.6122 64 Mapoly0065s0046 [PTHR15327:SF0] SUBFAMILY NOT NAMED; [PTHR15327] MICROFIBRIL-ASSOCIATED PROTEIN; [KOG1425] Microfibrillar-associated protein MFAP1; [PF06991] Splicing factor, Prp19-binding domain; [K13110] microfibrillar-associated protein 1 136.01 0.6069 65 Mapoly0052s0086 [PF05641] Agenet domain; [PTHR31917] FAMILY NOT NAMED 136.25 0.6169 66 Mapoly0034s0044 [PTHR11469:SF2] GLUCOSE-6-PHOSPHATE ISOMERASE; [K01810] glucose-6-phosphate isomerase [EC:5.3.1.9]; [KOG2446] Glucose-6-phosphate isomerase; [GO:0006096] glycolysis; [5.3.1.9] Glucose-6-phosphate isomerase.; [PF00342] Phosphoglucose isomerase; [GO:0004347] glucose-6-phosphate isomerase activity; [GO:0006094] gluconeogenesis; [PTHR11469] GLUCOSE-6-PHOSPHATE ISOMERASE 136.54 0.5258 67 Mapoly0119s0048 [PTHR21654] FAMILY NOT NAMED; [PTHR21654:SF0] SUBFAMILY NOT NAMED; [PF13837] Myb/SANT-like DNA-binding domain 137.63 0.6087 68 Mapoly0028s0110 [GO:0005524] ATP binding; [PTHR23069] TAT-BINDING HOMOLOG 7; [PTHR23069:SF0] SUBFAMILY NOT NAMED; [GO:0005515] protein binding; [PF00439] Bromodomain; [PF00004] ATPase family associated with various cellular activities (AAA); [KOG0732] AAA+-type ATPase containing the bromodomain 137.80 0.6095 69 Mapoly0002s0191 [GO:0008168] methyltransferase activity; [PTHR10108] METHYLTRANSFERASE; [PF08241] Methyltransferase domain; [GO:0008152] metabolic process; [KOG4300] Predicted methyltransferase 137.93 0.5711 70 Mapoly0061s0016 [PTHR10774] EXTENDED SYNAPTOTAGMIN-RELATED; [KOG1030] Predicted Ca2+-dependent phospholipid-binding protein; [PF00168] C2 domain; [GO:0005515] protein binding 138.32 0.4945 71 Mapoly0045s0049 - 139.71 0.5996 72 Mapoly0005s0237 - 143.61 0.5688 73 Mapoly0120s0055 [GO:0003677] DNA binding; [PTHR12486] APRATAXIN-RELATED; [PF13671] AAA domain; [PF01661] Macro domain; [GO:0006281] DNA repair; [KOG0562] Predicted hydrolase (HIT family); [PF11969] Scavenger mRNA decapping enzyme C-term binding; [GO:0033699] DNA 5'-adenosine monophosphate hydrolase activity; [PF10283] Zinc-finger (CX5CX6HX5H) motif; [3.-.-.-] Hydrolases.; [K10863] aprataxin [EC:3.-.-.-]; [PTHR12486:SF4] APRATAXIN (FORKHEAD-ASSOCIATED DOMAIN HISTIDINE-TRIAD LIKE PROTEIN) 145.09 0.5139 74 Mapoly0004s0006 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [KOG0600] Cdc2-related protein kinase; [PTHR24056] CELL DIVISION PROTEIN KINASE 145.48 0.5910 75 Mapoly0015s0043 [3.1.2.15] Ubiquitin thiolesterase.; [PF00443] Ubiquitin carboxyl-terminal hydrolase; [K11858] ubiquitin carboxyl-terminal hydrolase 48 [EC:3.1.2.15]; [GO:0005515] protein binding; [GO:0006511] ubiquitin-dependent protein catabolic process; [PTHR24006:SF100] SUBFAMILY NOT NAMED; [KOG1863] Ubiquitin carboxyl-terminal hydrolase; [PF00240] Ubiquitin family; [PTHR24006] FAMILY NOT NAMED 146.72 0.6044 76 Mapoly0069s0077 [PTHR11736:SF14] MAGE-RELATED; [PTHR11736] MELANOMA-ASSOCIATED ANTIGEN (MAGE ANTIGEN); [PF01454] MAGE family; [KOG4562] Uncharacterized conserved protein (tumor-rejection antigen MAGE in humans) 147.89 0.5842 77 Mapoly0158s0003 [PF13921] Myb-like DNA-binding domain 149.80 0.5763 78 Mapoly0167s0006 - 150.01 0.6012 79 Mapoly0096s0011 [PTHR12436] 80 KDA MCM3-ASSOCIATED PROTEIN; [PF03399] SAC3/GANP/Nin1/mts3/eIF-3 p25 family 156.48 0.6011 80 Mapoly0144s0028 [GO:0016020] membrane; [PTHR11384] ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER; [GO:0005524] ATP binding; [KOG0060] Long-chain acyl-CoA transporter, ABC superfamily (involved in peroxisome organization and biogenesis); [PF06472] ABC transporter transmembrane region 2; [GO:0016887] ATPase activity; [GO:0006810] transport; [PF00005] ABC transporter 158.46 0.5882 81 Mapoly0001s0378 [PTHR32086] FAMILY NOT NAMED; [K10891] fanconi anemia group D2 protein; [GO:0006281] DNA repair; [KOG4712] Uncharacterized conserved protein; [PF14631] Fanconi anaemia protein FancD2 nuclease 160.32 0.6057 82 Mapoly0029s0003 [KOG1824] TATA-binding protein-interacting protein; [PTHR12696] TIP120; [PF08623] TATA-binding protein interacting (TIP20); [PF13646] HEAT repeats 160.54 0.6072 83 Mapoly0042s0035 [PF01433] Peptidase family M1; [GO:0008237] metallopeptidase activity; [3.4.11.2] Membrane alanyl aminopeptidase.; [GO:0008270] zinc ion binding; [PTHR11533] PROTEASE M1 ZINC METALLOPROTEASE; [KOG1046] Puromycin-sensitive aminopeptidase and related aminopeptidases; [K01256] aminopeptidase N [EC:3.4.11.2]; [GO:0006508] proteolysis; [PF11940] Domain of unknown function (DUF3458) 161.97 0.5802 84 Mapoly0080s0093 [GO:0003677] DNA binding; [PF00046] Homeobox domain; [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR12628] POLYCOMB-LIKE TRANSCRIPTION FACTOR 162.89 0.5964 85 Mapoly0002s0237 [PTHR12864] RAN BINDING PROTEIN 9-RELATED; [PF10607] CTLH/CRA C-terminal to LisH motif domain; [GO:0005515] protein binding; [KOG1477] SPRY domain-containing proteins; [PTHR12864:SF1] RAN BINDING PROTEIN 9-RELATED; [PF00622] SPRY domain 163.37 0.5693 86 Mapoly0002s0019 [PF00919] Uncharacterized protein family UPF0004; [PF04055] Radical SAM superfamily; [GO:0051539] 4 iron, 4 sulfur cluster binding; [GO:0009451] RNA modification; [KOG4355] Predicted Fe-S oxidoreductase; [GO:0003824] catalytic activity; [GO:0051536] iron-sulfur cluster binding; [PTHR11918:SF45] UNCHARACTERIZED; [PTHR11918] RADICAL SAM PROTEINS; [PF01938] TRAM domain 165.30 0.4837 87 Mapoly0007s0083 - 165.81 0.5709 88 Mapoly0009s0011 [PF06650] Protein of unknown function (DUF1162); [PTHR16166] VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN (VPS13); [PF12624] N-terminal region of Chorein, a TM vesicle-mediated sorter 167.01 0.5894 89 Mapoly0001s0369 [K12879] THO complex subunit 2; [PF11262] Transcription factor/nuclear export subunit protein 2; [PTHR21597] THO2 PROTEIN; [PF11732] Transcription- and export-related complex subunit; [PTHR21597:SF0] SUBFAMILY NOT NAMED; [KOG1874] KEKE-like motif-containing transcription regulator (Rlr1)/suppressor of sin4 167.41 0.6035 90 Mapoly0156s0011 [PTHR24067] UBIQUITIN-CONJUGATING ENZYME E2; [GO:0016881] acid-amino acid ligase activity; [6.3.2.19] Ubiquitin--protein ligase.; [KOG0417] Ubiquitin-protein ligase; [K10581] ubiquitin-conjugating enzyme E2 O [EC:6.3.2.19]; [PF00179] Ubiquitin-conjugating enzyme 167.79 0.5409 91 Mapoly0043s0062 [GO:0003677] DNA binding; [GO:0006284] base-excision repair; [PTHR10359] A/G-SPECIFIC ADENINE GLYCOSYLASE/ENDONUCLEASE III; [PF14815] NUDIX domain; [K03575] A/G-specific adenine glycosylase [EC:3.2.2.-]; [KOG1921] Endonuclease III; [PF00730] HhH-GPD superfamily base excision DNA repair protein; [PF00633] Helix-hairpin-helix motif; [3.2.2.-] Hydrolyzing N-glycosyl compounds. 169.78 0.5928 92 Mapoly0114s0035 [PTHR31169] FAMILY NOT NAMED; [PF10497] Zinc-finger domain of monoamine-oxidase A repressor R1 171.02 0.5978 93 Mapoly0065s0050 [KOG0998] Synaptic vesicle protein EHS-1 and related EH domain proteins; [PTHR11216] EH DOMAIN; [GO:0005509] calcium ion binding; [PF13202] EF hand; [PF12763] Cytoskeletal-regulatory complex EF hand 172.08 0.5616 94 Mapoly0112s0033 [KOG0978] E3 ubiquitin ligase involved in syntaxin degradation; [PTHR13140] MYOSIN 172.34 0.5648 95 Mapoly0006s0051 [PF13917] Zinc knuckle; [KOG2985] Uncharacterized conserved protein; [PTHR31437] FAMILY NOT NAMED 173.94 0.5697 96 Mapoly0027s0147 [PTHR12585] SCC1 / RAD21 FAMILY MEMBER; [PF04824] Conserved region of Rad21 / Rec8 like protein; [GO:0005515] protein binding; [PF04825] N terminus of Rad21 / Rec8 like protein; [K06670] cohesin complex subunit SCC1; [GO:0000228] nuclear chromosome; [KOG1213] Sister chromatid cohesion complex Cohesin, subunit RAD21/SCC1 174.02 0.5955 97 Mapoly0052s0075 - 174.62 0.5063 98 Mapoly0047s0119 [KOG0891] DNA-dependent protein kinase; [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [PF08771] Rapamycin binding domain; [K07203] FKBP12-rapamycin complex-associated protein; [GO:0005515] protein binding; [GO:0008144] drug binding; [PF11865] Domain of unknown function (DUF3385); [PF00454] Phosphatidylinositol 3- and 4-kinase; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED 176.76 0.5916 99 Mapoly0004s0286 [PTHR12663:SF0] SUBFAMILY NOT NAMED; [K11267] sister chromatid cohesion protein PDS5; [PTHR12663] ANDROGEN INDUCED INHIBITOR OF PROLIFERATION (AS3) / PDS5-RELATED; [KOG1525] Sister chromatid cohesion complex Cohesin, subunit PDS5 177.06 0.6014 100 Mapoly0022s0155 - 178.06 0.5151 101 Mapoly0069s0084 [3.6.5.5] Dynamin GTPase.; [KOG0446] Vacuolar sorting protein VPS1, dynamin, and related proteins; [K01528] dynamin GTPase [EC:3.6.5.5]; [PF02212] Dynamin GTPase effector domain; [PF00350] Dynamin family; [PTHR11566] DYNAMIN; [GO:0003924] GTPase activity; [PTHR11566:SF21] SUBFAMILY NOT NAMED; [GO:0005525] GTP binding; [PF01031] Dynamin central region 180.93 0.5863 102 Mapoly0015s0183 [GO:0000922] spindle pole; [PF04130] Spc97 / Spc98 family; [GO:0000226] microtubule cytoskeleton organization; [GO:0005815] microtubule organizing center; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN 181.27 0.5688 103 Mapoly0099s0003 [GO:0000922] spindle pole; [PF04130] Spc97 / Spc98 family; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN 183.30 0.5898 104 Mapoly0010s0062 [KOG2250] Glutamate/leucine/phenylalanine/valine dehydrogenases; [GO:0055114] oxidation-reduction process; [PTHR11606] GLUTAMATE DEHYDROGENASE; [GO:0016491] oxidoreductase activity; [PF00208] Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; [K00262] glutamate dehydrogenase (NADP+) [EC:1.4.1.4]; [GO:0006520] cellular amino acid metabolic process; [PTHR11606:SF4] SUBFAMILY NOT NAMED; [1.4.1.4] Glutamate dehydrogenase (NADP(+)).; [PF02812] Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 184.21 0.5948 105 Mapoly0027s0186 [GO:0005524] ATP binding; [K10866] DNA repair protein RAD50 [EC:3.6.-.-]; [PF13476] AAA domain; [GO:0008270] zinc ion binding; [PF04423] Rad50 zinc hook motif; [3.6.-.-] Acting on acid anhydrides.; [GO:0006281] DNA repair; [KOG0962] DNA repair protein RAD50, ABC-type ATPase/SMC superfamily; [PTHR18867:SF12] SUBFAMILY NOT NAMED; [PTHR18867] RAD50; [GO:0004518] nuclease activity; [GO:0030870] Mre11 complex; [PF13558] Putative exonuclease SbcCD, C subunit 185.16 0.5889 106 Mapoly0026s0077 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [2.7.11.1] Non-specific serine/threonine protein kinase.; [PF08064] UME (NUC010) domain; [PF00454] Phosphatidylinositol 3- and 4-kinase; [K06640] ataxia telangiectasia and Rad3 related [EC:2.7.11.1]; [GO:0004674] protein serine/threonine kinase activity; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [KOG0890] Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination 185.39 0.5939 107 Mapoly0011s0201 [GO:0031625] ubiquitin protein ligase binding; [GO:0031461] cullin-RING ubiquitin ligase complex; [KOG2166] Cullins; [GO:0006511] ubiquitin-dependent protein catabolic process; [PF10557] Cullin protein neddylation domain; [K03869] cullin 3; [PTHR11932] CULLIN; [PF00888] Cullin family 186.02 0.5606 108 Mapoly0036s0012 [GO:0003723] RNA binding; [KOG3013] Exosomal 3'-5' exoribonuclease complex, subunit Rrp4; [PTHR21321] PNAS-3 RELATED; [PTHR21321:SF1] PNAS-3 RELATED; [K03679] exosome complex component RRP4; [GO:0000178] exosome (RNase complex) 187.49 0.5370 109 Mapoly0013s0180 [PF12329] TATA element modulatory factor 1 DNA binding; [PTHR13140] MYOSIN; [KOG4673] Transcription factor TMF, TATA element modulatory factor; [PF12325] TATA element modulatory factor 1 TATA binding 187.66 0.5834 110 Mapoly0014s0204 [PTHR24012] FAMILY NOT NAMED; [PTHR24012:SF31] SUBFAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 187.82 0.5873 111 Mapoly0002s0007 [GO:0003723] RNA binding; [GO:0001522] pseudouridine synthesis; [GO:0009451] RNA modification; [GO:0009982] pseudouridine synthase activity; [PF00849] RNA pseudouridylate synthase; [PTHR21600] RIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE SYNTHASE B; [PF01479] S4 domain 188.39 0.5667 112 Mapoly0067s0087 [PF04788] Protein of unknown function (DUF620); [PTHR31300] FAMILY NOT NAMED 192.61 0.5385 113 Mapoly0005s0045 [PF15628] RRM in Demeter; [PTHR10359] A/G-SPECIFIC ADENINE GLYCOSYLASE/ENDONUCLEASE III 192.80 0.5980 114 Mapoly0002s0028 [PF00630] Filamin/ABP280 repeat; [GO:0003676] nucleic acid binding; [KOG0146] RNA-binding protein ETR-3 (RRM superfamily); [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 194.21 0.5875 115 Mapoly0004s0058 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PTHR13215:SF4] SUBFAMILY NOT NAMED; [PF08766] DEK C terminal domain; [PF02229] Transcriptional Coactivator p15 (PC4); [KOG2712] Transcriptional coactivator; [PTHR13215] RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; [GO:0003713] transcription coactivator activity 196.15 0.5820 116 Mapoly0134s0010 [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PF12726] SEN1 N terminal; [PF13086] AAA domain; [KOG2812] Uncharacterized conserved protein; [PF13087] AAA domain 197.64 0.5751 117 Mapoly0001s0391 [GO:0005634] nucleus; [PF05965] F/Y rich C-terminus 198.80 0.5884 118 Mapoly0059s0047 [PTHR23092] TOPOISOMERASE-RELATED PROTEIN; [PF01909] Nucleotidyltransferase domain; [GO:0016779] nucleotidyltransferase activity; [PTHR23092:SF15] SUBFAMILY NOT NAMED; [PF10539] Development and cell death domain 200.24 0.5726 119 Mapoly0014s0115 [PTHR15137] TRANSCRIPTION INITIATION FACTOR TFIID; [PF01433] Peptidase family M1; [GO:0008237] metallopeptidase activity; [GO:0008270] zinc ion binding; [K03128] transcription initiation factor TFIID subunit 2; [KOG1932] TATA binding protein associated factor 202.22 0.5678 120 Mapoly0021s0012 [PF00443] Ubiquitin carboxyl-terminal hydrolase; [GO:0006511] ubiquitin-dependent protein catabolic process; [PF02810] SEC-C motif; [KOG1865] Ubiquitin carboxyl-terminal hydrolase; [PTHR24006] FAMILY NOT NAMED; [PF01753] MYND finger 202.68 0.5753 121 Mapoly0001s0263 [PF08766] DEK C terminal domain; [GO:0005515] protein binding; [KOG1946] RNA polymerase I transcription factor UAF; [PF02201] SWIB/MDM2 domain; [PTHR13844] BRG-1 ASSOCIATED FACTOR 60 (BAF60) 203.88 0.5389 122 Mapoly0002s0004 [KOG1189] Global transcriptional regulator, cell division control protein; [PF00557] Metallopeptidase family M24; [PF08512] Histone chaperone Rttp106-like; [PTHR13980] CDC68 RELATED; [PF08644] FACT complex subunit (SPT16/CDC68) 204.73 0.5766 123 Mapoly0001s0195 [GO:0070985] TFIIK complex; [GO:0006355] regulation of transcription, DNA-dependent; [GO:0016538] cyclin-dependent protein serine/threonine kinase regulator activity; [GO:0019901] protein kinase binding; [PTHR10026:SF8] CYCLIN H; [PF00134] Cyclin, N-terminal domain; [PTHR10026] CYCLIN; [KOG2496] Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, cyclin H subunit; [GO:0006351] transcription, DNA-dependent; [GO:0000079] regulation of cyclin-dependent protein serine/threonine kinase activity 206.64 0.5618 124 Mapoly0159s0020 [K05544] tRNA-dihydrouridine synthase 3 [EC:1.-.-.-]; [GO:0050660] flavin adenine dinucleotide binding; [GO:0055114] oxidation-reduction process; [PTHR11082:SF8] TRNA-DIHYDROURIDINE SYNTHASE 3; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PF01207] Dihydrouridine synthase (Dus); [KOG2333] Uncharacterized conserved protein; [GO:0008033] tRNA processing; [PTHR11082] TRNA-DIHYDROURIDINE SYNTHASE; [GO:0046872] metal ion binding; [GO:0017150] tRNA dihydrouridine synthase activity; [1.-.-.-] Oxidoreductases. 206.75 0.5756 125 Mapoly0082s0054 [PF10358] N-terminal C2 in EEIG1 and EHBP1 proteins; [PTHR31593] FAMILY NOT NAMED; [PTHR31593:SF0] SUBFAMILY NOT NAMED 211.44 0.5481 126 Mapoly0031s0039 [GO:0003677] DNA binding; [PTHR13408] DNA-DIRECTED RNA POLYMERASE III; [PF05132] RNA polymerase III RPC4; [PTHR13408:SF0] SUBFAMILY NOT NAMED; [GO:0005666] DNA-directed RNA polymerase III complex; [GO:0003899] DNA-directed RNA polymerase activity; [GO:0006383] transcription from RNA polymerase III promoter 211.64 0.5446 127 Mapoly0005s0056 [GO:0005524] ATP binding; [PTHR11752] HELICASE SKI2W; [KOG0947] Cytoplasmic exosomal RNA helicase SKI2, DEAD-box superfamily; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF08148] DSHCT (NUC185) domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [PF13234] rRNA-processing arch domain; [GO:0003676] nucleic acid binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [K12599] antiviral helicase SKI2 [EC:3.6.4.-] 212.82 0.5824 128 Mapoly0126s0027 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0390] DNA repair protein, SNF2 family; [PF00271] Helicase conserved C-terminal domain 212.95 0.5630 129 Mapoly0061s0115 [PTHR23079] RNA-DEPENDENT RNA POLYMERASE; [GO:0003968] RNA-directed RNA polymerase activity; [PTHR23079:SF1] RNA-DEPENDENT RNA POLYMERASE; [KOG0988] RNA-directed RNA polymerase QDE-1 required for posttranscriptional gene silencing and RNA interference; [PF05183] RNA dependent RNA polymerase 213.49 0.5173 130 Mapoly0001s0415 [PF05641] Agenet domain 215.56 0.5490 131 Mapoly0130s0046 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF14493] Helix-turn-helix domain; [PF09382] RQC domain; [K10900] werner syndrome ATP-dependent helicase [EC:3.6.4.12]; [KOG0353] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 215.81 0.5881 132 Mapoly0158s0020 - 217.13 0.4739 133 Mapoly0014s0134 [KOG2442] Uncharacterized conserved protein, contains PA domain; [PF02225] PA domain; [PTHR12174] SIGNAL PEPTIDE PEPTIDASE; [GO:0016021] integral to membrane; [PF04258] Signal peptide peptidase; [GO:0004190] aspartic-type endopeptidase activity 218.25 0.5732 134 Mapoly0085s0092 [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding 218.75 0.5597 135 Mapoly0111s0052 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [KOG1015] Transcription regulator XNP/ATRX, DEAD-box superfamily; [K11681] helicase SWR1 [EC:3.6.4.12]; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [3.6.4.12] DNA helicase.; [PF00271] Helicase conserved C-terminal domain; [PF07529] HSA; [PF13921] Myb-like DNA-binding domain 221.71 0.5866 136 Mapoly0105s0028 [PTHR24012] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 223.49 0.5724 137 Mapoly0024s0108 [PF13371] Tetratricopeptide repeat; [PTHR23082] TRANSCRIPTION INITIATION FACTOR IIIC (TFIIIC), POLYPEPTIDE 3-RELATED; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13174] Tetratricopeptide repeat; [KOG2076] RNA polymerase III transcription factor TFIIIC 223.99 0.5726 138 Mapoly0153s0011 [PF13871] Helicase_C-like; [GO:0006355] regulation of transcription, DNA-dependent; [KOG1513] Nuclear helicase MOP-3/SNO (DEAD-box superfamily); [PTHR12706] STRAWBERRY NOTCH-RELATED; [PF13872] P-loop containing NTP hydrolase pore-1 225.06 0.5870 139 Mapoly0001s0348 [KOG1342] Histone deacetylase complex, catalytic component RPD3; [PF00850] Histone deacetylase domain; [PTHR10625] HISTONE DEACETYLASE 226.30 0.5667 140 Mapoly0117s0005 [K13109] IK cytokine; [PTHR12765] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [KOG2498] IK cytokine down-regulator of HLA class II; [PF07807] RED-like protein C-terminal region; [PTHR12765:SF5] RED PROTEIN (IK FACTOR) (CYTOKINE IK); [GO:0005634] nucleus; [PF07808] RED-like protein N-terminal region 226.48 0.5878 141 Mapoly0029s0152 [PTHR15239] UNCHARACTERIZED; [PF05833] Fibronectin-binding protein A N-terminus (FbpA); [PTHR15239:SF1] COLON CANCER ANTIGEN 1; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding; [PF11923] Domain of unknown function (DUF3441); [KOG2030] Predicted RNA-binding protein; [PF05670] Domain of unknown function (DUF814) 226.56 0.5668 142 Mapoly0039s0014 [PTHR23125] F-BOX/LEUCINE RICH REPEAT PROTEIN 227.24 0.5559 143 Mapoly0011s0057 [PF13837] Myb/SANT-like DNA-binding domain 227.40 0.5853 144 Mapoly0012s0166 [PF09405] CASC3/Barentsz eIF4AIII binding; [PTHR22814:SF47] HEAVY-METAL-ASSOCIATED DOMAIN-CONTAINING PROTEIN; [PTHR22814] COPPER TRANSPORT PROTEIN ATOX1-RELATED 229.56 0.5778 145 Mapoly0037s0093 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG4280] Kinesin-like protein; [PTHR24115:SF87] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [PF12711] Kinesin motor; [GO:0003777] microtubule motor activity 229.71 0.5814 146 Mapoly0010s0012 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF06461] Domain of Unknown Function (DUF1086); [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00176] SNF2 family N-terminal domain; [PF06465] Domain of Unknown Function (DUF1087); [3.6.4.12] DNA helicase.; [PF00271] Helicase conserved C-terminal domain; [K11643] chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12]; [KOG0384] Chromodomain-helicase DNA-binding protein 230.36 0.5918 147 Mapoly0073s0063 [GO:0016020] membrane; [GO:0005524] ATP binding; [GO:0017038] protein import; [PF07516] SecA Wing and Scaffold domain; [PTHR30612] SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM; [PF07517] SecA DEAD-like domain; [PF01043] SecA preprotein cross-linking domain; [K03070] preprotein translocase subunit SecA 230.38 0.5345 148 Mapoly0054s0061 [KOG3228] Uncharacterized conserved protein 233.69 0.5370 149 Mapoly0091s0017 [GO:0005515] protein binding; [PTHR22937] RING FINGER CONTAINING PROTEIN; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [KOG2177] Predicted E3 ubiquitin ligase; [K11985] TRAF-interacting protein 233.87 0.5746 150 Mapoly0091s0001 [PTHR14190:SF7] SUBFAMILY NOT NAMED; [PF04129] Vps52 / Sac2 family; [KOG1961] Vacuolar sorting protein VPS52/suppressor of actin Sac2; [PTHR14190] SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52 235.73 0.5478 151 Mapoly0105s0015 [GO:0003677] DNA binding; [KOG2393] Transcription initiation factor IIF, large subunit (RAP74); [GO:0032968] positive regulation of transcription elongation from RNA polymerase II promoter; [K03138] transcription initiation factor TFIIF subunit alpha; [PF05793] Transcription initiation factor IIF, alpha subunit (TFIIF-alpha); [PTHR13011] TFIIF-ALPHA; [GO:0005634] nucleus; [GO:0006367] transcription initiation from RNA polymerase II promoter 236.17 0.5714 152 Mapoly0014s0195 [PTHR10641:SF17] CELL DIVISION CYCLE 5-LIKE PROTEIN; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [PF13921] Myb-like DNA-binding domain; [PF11831] pre-mRNA splicing factor component; [K12860] pre-mRNA-splicing factor CDC5/CEF1 239.85 0.5824 153 Mapoly0187s0011 [KOG1737] Oxysterol-binding protein; [PTHR10972] OXYSTEROL-BINDING PROTEIN-RELATED; [PF01237] Oxysterol-binding protein 241.83 0.5006 154 Mapoly0061s0069 [K09422] myb proto-oncogene protein, plant; [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding; [PF13921] Myb-like DNA-binding domain 243.97 0.5700 155 Mapoly0051s0067 [PF00651] BTB/POZ domain; [PTHR24411] FAMILY NOT NAMED; [PF00917] MATH domain; [GO:0005515] protein binding; [KOG1987] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains 244.71 0.5607 156 Mapoly0033s0105 [PF03470] XS zinc finger domain; [PTHR21596] RIBONUCLEASE P PROTEIN SUBUNIT P38-RELATED; [PF03468] XS domain; [GO:0031047] gene silencing by RNA 248.41 0.5456 157 Mapoly0140s0037 [KOG1339] Aspartyl protease; [PF14543] Xylanase inhibitor N-terminal; [PTHR13683] ASPARTYL PROTEASES; [PF14541] Xylanase inhibitor C-terminal; [GO:0004190] aspartic-type endopeptidase activity; [GO:0006508] proteolysis 248.62 0.4535 158 Mapoly0043s0012 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [K13123] G patch domain-containing protein 1; [PTHR13384] FAMILY NOT NAMED; [KOG2138] Predicted RNA binding protein, contains G-patch domain; [PF07713] Protein of unknown function (DUF1604); [PF01805] Surp module 250.49 0.5830 159 Mapoly0019s0083 [PTHR20854] INOSITOL MONOPHOSPHATASE; [GO:0046854] phosphatidylinositol phosphorylation; [PF00459] Inositol monophosphatase family; [PTHR20854:SF4] MYO INOSITOL MONOPHOSPHATASE; [KOG2951] Inositol monophosphatase 250.97 0.5215 160 Mapoly0024s0107 [PF07719] Tetratricopeptide repeat; [GO:0005515] protein binding; [PF13414] TPR repeat; [K03350] anaphase-promoting complex subunit 3; [KOG1126] DNA-binding cell division cycle control protein; [PF13181] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat; [PTHR12558] CELL DIVISION CYCLE 16,23,27; [PTHR12558:SF11] CELL DIVISION CYCLE 27; [PF12895] Anaphase-promoting complex, cyclosome, subunit 3 252.08 0.5704 161 Mapoly0063s0071 [GO:0005515] protein binding; [K12176] COP9 signalosome complex subunit 2; [KOG1464] COP9 signalosome, subunit CSN2; [PF01399] PCI domain; [PTHR10678] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 252.29 0.5710 162 Mapoly0001s0208 [PTHR31431] FAMILY NOT NAMED; [KOG4833] Uncharacterized conserved protein; [K14311] nuclear pore complex protein Nup188; [PF10487] Nucleoporin subcomplex protein binding to Pom34 252.44 0.5720 163 Mapoly0143s0007 [PF08314] Secretory pathway protein Sec39; [PTHR15922:SF2] SUBFAMILY NOT NAMED; [PTHR15922] FAMILY NOT NAMED 255.19 0.5539 164 Mapoly0001s0355 [GO:0016020] membrane; [GO:0004222] metalloendopeptidase activity; [PF01457] Leishmanolysin; [PF07974] EGF-like domain; [KOG2556] Leishmanolysin-like peptidase (Peptidase M8 family); [3.4.24.36] Leishmanolysin.; [GO:0007155] cell adhesion; [GO:0006508] proteolysis; [K01404] leishmanolysin [EC:3.4.24.36]; [PTHR10942] LEISHMANOLYSIN-LIKE PEPTIDASE 258.73 0.5665 165 Mapoly0004s0120 [PF04998] RNA polymerase Rpb1, domain 5; [GO:0003677] DNA binding; [PF00623] RNA polymerase Rpb1, domain 2; [PTHR19376] DNA-DIRECTED RNA POLYMERASE; [PF05000] RNA polymerase Rpb1, domain 4; [PF11523] Protein of unknown function (DUF3223); [PF04997] RNA polymerase Rpb1, domain 1; [GO:0006351] transcription, DNA-dependent; [GO:0003899] DNA-directed RNA polymerase activity; [PF04983] RNA polymerase Rpb1, domain 3; [KOG0261] RNA polymerase III, large subunit; [PTHR19376:SF33] DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'' 259.14 0.5536 166 Mapoly0251s0001 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [KOG0663] Protein kinase PITSLRE and related kinases; [K08818] cell division cycle 2-like [EC:2.7.11.22]; [PTHR24056:SF107] CELL DIVISION PROTEIN KINASE 2 (CDC2-RELATED KINASE); [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 260.02 0.5734 167 Mapoly0016s0143 [KOG3783] Uncharacterized conserved protein; [PTHR31859] FAMILY NOT NAMED; [PF10300] Protein of unknown function (DUF3808) 265.97 0.4586 168 Mapoly0100s0059 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [GO:0004672] protein kinase activity; [6.3.2.19] Ubiquitin--protein ligase.; [K10143] E3 ubiquitin-protein ligase RFWD2 [EC:6.3.2.19]; [GO:0006468] protein phosphorylation; [KOG0316] Conserved WD40 repeat-containing protein; [PF00400] WD domain, G-beta repeat 266.05 0.4804 169 Mapoly0005s0041 [GO:0005524] ATP binding; [KOG0737] AAA+-type ATPase; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR23074] AAA ATPASE 266.88 0.4900 170 Mapoly0011s0209 - 267.17 0.5503 171 Mapoly0032s0133 [PF12432] Protein of unknown function (DUF3677); [PTHR21224:SF1] SUBFAMILY NOT NAMED; [K13138] integrator complex subunit 1; [PTHR21224] UNCHARACTERIZED 269.23 0.5502 172 Mapoly0041s0111 - 270.50 0.5165 173 Mapoly0013s0185 [PF03109] ABC1 family; [PTHR10566] CHAPERONE-ACTIVITY OF BC1 COMPLEX (CABC1)-RELATED; [KOG1235] Predicted unusual protein kinase; [PF01636] Phosphotransferase enzyme family 272.49 0.4307 174 Mapoly0133s0014 [PTHR23125] F-BOX/LEUCINE RICH REPEAT PROTEIN 273.02 0.5228 175 Mapoly0069s0088 - 273.54 0.5454 176 Mapoly0010s0203 [KOG4593] Mitotic checkpoint protein MAD1 275.91 0.5231 177 Mapoly0055s0120 - 276.10 0.5682 178 Mapoly0050s0099 [PF10433] Mono-functional DNA-alkylating methyl methanesulfonate N-term; [KOG1897] Damage-specific DNA binding complex, subunit DDB1 279.54 0.5657 179 Mapoly0043s0034 [PTHR13233] MICROSPHERULE PROTEIN 1; [GO:0005515] protein binding; [PTHR13233:SF0] SUBFAMILY NOT NAMED; [PF13325] N-terminal region of micro-spherule protein; [PF00498] FHA domain 280.63 0.5741 180 Mapoly0069s0061 [GO:0004677] DNA-dependent protein kinase activity; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [K06642] DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]; [PF08163] NUC194 domain; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0005634] nucleus; [PF00454] Phosphatidylinositol 3- and 4-kinase; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [GO:0006303] double-strand break repair via nonhomologous end joining 282.34 0.5362 181 Mapoly0140s0044 [GO:0005524] ATP binding; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [PTHR24361:SF148] SERINE/THREONINE PROTEIN KINASE; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24361] MITOGEN-ACTIVATED KINASE KINASE KINASE 283.74 0.5608 182 Mapoly0045s0054 [KOG1928] Alpha-1,4-N-acetylglucosaminyltransferase; [PF04572] Alpha 1,4-glycosyltransferase conserved region; [PF04488] Glycosyltransferase sugar-binding region containing DXD motif; [PTHR12042] LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE (ALPHA- 1,4-GALACTOSYLTRANSFERASE) 285.57 0.5354 183 Mapoly0046s0118 [PF00395] S-layer homology domain 285.61 0.5092 184 Mapoly0054s0064 [PF03178] CPSF A subunit region; [PF10433] Mono-functional DNA-alkylating methyl methanesulfonate N-term; [PTHR10644:SF3] DNA DAMAGE-BINDING PROTEIN 1 (DAMAGE-SPECIFIC DNA-BINDING PROTEIN 1)(UV-DAMAGED DNA-BINDING FACTOR); [K10610] DNA damage-binding protein 1; [GO:0005634] nucleus; [PTHR10644] DNA REPAIR/RNA PROCESSING CPSF FAMILY; [KOG1897] Damage-specific DNA binding complex, subunit DDB1; [GO:0003676] nucleic acid binding 285.70 0.5317 185 Mapoly0002s0236 [PTHR10782:SF4] SUBFAMILY NOT NAMED; [PTHR10782] ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; [GO:0008270] zinc ion binding; [GO:0019789] SUMO ligase activity; [PF02891] MIZ/SP-RING zinc finger 285.81 0.5560 186 Mapoly0068s0092 [GO:0003723] RNA binding; [PF00013] KH domain 286.37 0.5649 187 Mapoly0061s0085 [PF14868] Domain of unknown function (DUF4487) 288.54 0.5650 188 Mapoly0013s0150 [PF07714] Protein tyrosine kinase; [PF00564] PB1 domain; [KOG0192] Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs; [PTHR23257] SERINE-THREONINE PROTEIN KINASE; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation 289.57 0.4915 189 Mapoly0004s0007 [PTHR20208:SF10] SLX1 (YEAST)-LIKE ENDONUCLEASE; [PF01541] GIY-YIG catalytic domain; [PTHR20208] FAMILY NOT NAMED 290.30 0.5316 190 Mapoly0016s0207 - 290.75 0.4466 191 Mapoly0007s0247 [PF00168] C2 domain; [GO:0005515] protein binding 290.90 0.5207 192 Mapoly0043s0131 [PF06465] Domain of Unknown Function (DUF1087) 292.57 0.5217 193 Mapoly0048s0100 [PTHR18937:SF8] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC3; [GO:0005524] ATP binding; [KOG0964] Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3); [GO:0008280] cohesin core heterodimer; [GO:0005515] protein binding; [GO:0003682] chromatin binding; [GO:0007064] mitotic sister chromatid cohesion; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain; [K06669] structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) 292.71 0.5641 194 Mapoly0072s0016 [GO:0005515] protein binding; [PTHR15398] BROMODOMAIN-CONTAINING PROTEIN 8; [PF00439] Bromodomain; [K11321] bromodomain-containing protein 8; [PTHR15398:SF0] SUBFAMILY NOT NAMED 294.56 0.5463 195 Mapoly0050s0093 [GO:0008375] acetylglucosaminyltransferase activity; [GO:0016020] membrane; [PF02485] Core-2/I-Branching enzyme; [PTHR31042] FAMILY NOT NAMED 295.82 0.4713 196 Mapoly0100s0047 [KOG3263] Nucleic acid binding protein; [PTHR22849] WDSAM1 PROTEIN; [GO:0016567] protein ubiquitination; [GO:0004842] ubiquitin-protein ligase activity; [PF04564] U-box domain 297.32 0.5151 197 Mapoly0004s0034 [PTHR21738:SF0] SUBFAMILY NOT NAMED; [PTHR21738] UNCHARACTERIZED; [KOG3190] Uncharacterized conserved protein; [PF06102] Domain of unknown function (DUF947) 301.10 0.5118 198 Mapoly0024s0008 [GO:0003677] DNA binding; [KOG1793] Uncharacterized conserved protein; [PF08711] TFIIS helical bundle-like domain; [GO:0005634] nucleus; [GO:0006351] transcription, DNA-dependent; [PTHR22908] MIDASIN-RELATED 303.00 0.5090 199 Mapoly0013s0076 [PTHR23029] PHOSPHOGLYCERATE MUTASE; [KOG0235] Phosphoglycerate mutase; [PF00300] Histidine phosphatase superfamily (branch 1) 303.32 0.4504 200 Mapoly0013s0062 [GO:0003677] DNA binding; [PTHR15348:SF0] SUBFAMILY NOT NAMED; [PF01388] ARID/BRIGHT DNA binding domain; [GO:0005622] intracellular; [PTHR15348] AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN (ARID DOMAIN- CONTAINING PROTEIN) (DEAD RINGER PROTEIN) (B-CELL REGULATOR OF IGH TRANSCRIPTION) (BRIGHT) 307.28 0.5603