| 1 |
Mapoly0016s0170
| [PF13513] HEAT-like repeat; [PF03810] Importin-beta N-terminal domain; [GO:0006886] intracellular protein transport; [GO:0008536] Ran GTPase binding; [PTHR10527] IMPORTIN BETA; [KOG1241] Karyopherin (importin) beta 1; [K14293] importin subunit beta-1 | 1.00 | 0.8746 |
| 2 |
Mapoly0179s0012
| [GO:0016020] membrane; [PF00571] CBS domain; [GO:0006821] chloride transport; [PF00654] Voltage gated chloride channel; [GO:0055085] transmembrane transport; [GO:0005247] voltage-gated chloride channel activity; [GO:0030554] adenyl nucleotide binding; [PTHR11689] CHLORIDE CHANNEL | 2.83 | 0.8652 |
| 3 |
Mapoly0021s0008
| [PTHR12895] FAMILY NOT NAMED; [KOG2225] Proteins containing regions of low-complexity; [PF09742] Dyggve-Melchior-Clausen syndrome protein | 3.00 | 0.8669 |
| 4 |
Mapoly0004s0082
| [GO:0005515] protein binding; [PF00439] Bromodomain; [K11723] bromodomain-containing protein 7/9; [PTHR22881] BROMODOMAIN CONTAINING PROTEIN | 4.24 | 0.8725 |
| 5 |
Mapoly0010s0128
| [KOG4658] Apoptotic ATPase; [PTHR23155] LEUCINE-RICH REPEAT-CONTAINING PROTEIN; [GO:0043531] ADP binding; [PF00931] NB-ARC domain | 5.74 | 0.8035 |
| 6 |
Mapoly0005s0057
| [GO:0016787] hydrolase activity; [KOG1386] Nucleoside phosphatase; [PTHR11782] ADENOSINE/GUANOSINE DIPHOSPHATASE; [K01510] apyrase [EC:3.6.1.5]; [3.6.1.5] Apyrase.; [PF01150] GDA1/CD39 (nucleoside phosphatase) family | 6.93 | 0.8333 |
| 7 |
Mapoly0036s0035
| [PTHR23081] RNA POLYMERASE II CTD PHOSPHATASE; [PF03031] NLI interacting factor-like phosphatase; [GO:0005515] protein binding; [PF12738] twin BRCT domain | 7.75 | 0.8370 |
| 8 |
Mapoly0001s0292
| [KOG1913] Regucalcin gene promoter region-related protein (RGPR); [GO:0048208] COPII vesicle coating; [PF12932] Vesicle coat trafficking protein Sec16 mid-region; [PTHR13402] RGPR-RELATED; [PF12931] Sec23-binding domain of Sec16 | 7.94 | 0.8528 |
| 9 |
Mapoly0101s0011
| [GO:0005524] ATP binding; [PTHR19229] ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A (ABCA); [GO:0016887] ATPase activity; [KOG0059] Lipid exporter ABCA1 and related proteins, ABC superfamily; [K05648] ATP-binding cassette, subfamily A (ABC1), member 5; [PF12698] ABC-2 family transporter protein; [PF00005] ABC transporter | 8.66 | 0.8600 |
| 10 |
Mapoly0002s0011
| [K13145] integrator complex subunit 8; [PTHR13350] UNCHARACTERIZED | 10.20 | 0.8474 |
| 11 |
Mapoly0068s0063
| - | 10.39 | 0.8430 |
| 12 |
Mapoly0087s0075
| [PF09735] Membrane-associated apoptosis protein; [PTHR12093] FAMILY NOT NAMED; [KOG1917] Membrane-associated hematopoietic protein | 11.22 | 0.8289 |
| 13 |
Mapoly0008s0008
| [K14409] protein SMG7; [PTHR15696] SMG-7 (SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7); [PF10373] Est1 DNA/RNA binding domain; [PF10374] Telomerase activating protein Est1; [PTHR15696:SF0] SUBFAMILY NOT NAMED | 13.64 | 0.8531 |
| 14 |
Mapoly0044s0084
| [GO:0005524] ATP binding; [PTHR11752] HELICASE SKI2W; [KOG0948] Nuclear exosomal RNA helicase MTR4, DEAD-box superfamily; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF08148] DSHCT (NUC185) domain; [PF13234] rRNA-processing arch domain; [GO:0003676] nucleic acid binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 14.70 | 0.8077 |
| 15 |
Mapoly0006s0181
| [KOG0267] Microtubule severing protein katanin p80 subunit B (contains WD40 repeats); [GO:0005515] protein binding; [PTHR19845] KATANIN P80 SUBUNIT; [PF13925] con80 domain of Katanin; [PF00400] WD domain, G-beta repeat | 17.15 | 0.8115 |
| 16 |
Mapoly0092s0028
| [GO:0005515] protein binding; [PF00612] IQ calmodulin-binding motif; [PTHR25069] FAMILY NOT NAMED | 18.03 | 0.8084 |
| 17 |
Mapoly0100s0023
| [GO:0005086] ARF guanyl-nucleotide exchange factor activity; [PF12783] Guanine nucleotide exchange factor in Golgi transport N-terminal; [PTHR10663] GUANYL-NUCLEOTIDE EXCHANGE FACTOR; [PF01369] Sec7 domain; [GO:0032012] regulation of ARF protein signal transduction; [KOG0928] Pattern-formation protein/guanine nucleotide exchange factor | 19.75 | 0.8256 |
| 18 |
Mapoly0013s0141
| [PTHR19375] HEAT SHOCK PROTEIN 70KDA; [KOG0103] Molecular chaperones HSP105/HSP110/SSE1, HSP70 superfamily; [PTHR19375:SF78] SUBFAMILY NOT NAMED; [PF00012] Hsp70 protein | 20.20 | 0.8030 |
| 19 |
Mapoly0049s0111
| [GO:0016020] membrane; [PF13334] Domain of unknown function (DUF4094); [GO:0006486] protein glycosylation; [KOG2288] Galactosyltransferases; [GO:0008378] galactosyltransferase activity; [PF01762] Galactosyltransferase; [PTHR11214] BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE | 20.20 | 0.7881 |
| 20 |
Mapoly0002s0327
| [K01552] arsenite-transporting ATPase [EC:3.6.3.16]; [KOG0209] P-type ATPase; [GO:0000166] nucleotide binding; [GO:0016021] integral to membrane; [PF00702] haloacid dehalogenase-like hydrolase; [GO:0016887] ATPase activity; [3.6.3.-] Acting on acid anhydrides; catalyzing transmembrane movement of substances.; [GO:0006812] cation transport; [PTHR24093] FAMILY NOT NAMED; [PTHR24093:SF82] ATPASE, P-TYPE, HAD SUPERFAMILY, SUBFAMILY IC, PUTATIVE; [GO:0046872] metal ion binding; [PF00122] E1-E2 ATPase | 20.45 | 0.8134 |
| 21 |
Mapoly0004s0049
| [PF13414] TPR repeat; [PF00226] DnaJ domain; [PTHR24078] DNAJ HOMOLOG SUBFAMILY C MEMBER; [KOG0550] Molecular chaperone (DnaJ superfamily) | 23.22 | 0.8341 |
| 22 |
Mapoly0061s0124
| [PF03177] Non-repetitive/WGA-negative nucleoporin C-terminal; [K14300] nuclear pore complex protein Nup133; [PF08801] Nup133 N terminal like; [PTHR13405] FAMILY NOT NAMED | 24.72 | 0.8311 |
| 23 |
Mapoly0140s0029
| [GO:0016307] phosphatidylinositol phosphate kinase activity; [2.7.1.68] 1-phosphatidylinositol-4-phosphate 5-kinase.; [PF01504] Phosphatidylinositol-4-phosphate 5-Kinase; [KOG0229] Phosphatidylinositol-4-phosphate 5-kinase; [PTHR23086] PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE; [K00889] 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]; [GO:0046488] phosphatidylinositol metabolic process; [PF02493] MORN repeat | 25.50 | 0.7908 |
| 24 |
Mapoly0083s0022
| [PTHR15288] SUPPRESSION OF TUMORIGENICITY 5 (ST5); [PF02141] DENN (AEX-3) domain; [PF03456] uDENN domain | 27.13 | 0.7628 |
| 25 |
Mapoly0052s0038
| [KOG2280] Vacuolar assembly/sorting protein VPS16; [GO:0005737] cytoplasm; [PF04840] Vps16, C-terminal region; [PTHR12811] VACUOLAR PROTEIN SORTING VPS16; [PF04841] Vps16, N-terminal region; [GO:0006886] intracellular protein transport; [PTHR12811:SF0] SUBFAMILY NOT NAMED | 27.66 | 0.7939 |
| 26 |
Mapoly0002s0109
| [PF04765] Protein of unknown function (DUF616); [PTHR12956] ALKALINE CERAMIDASE-RELATED | 28.28 | 0.7282 |
| 27 |
Mapoly0045s0097
| [GO:0030130] clathrin coat of trans-Golgi network vesicle; [PF00637] Region in Clathrin and VPS; [GO:0016192] vesicle-mediated transport; [PF09268] Clathrin, heavy-chain linker; [PF13838] Clathrin-H-link; [K04646] clathrin heavy chain; [GO:0006886] intracellular protein transport; [GO:0030132] clathrin coat of coated pit; [KOG0985] Vesicle coat protein clathrin, heavy chain; [PF01394] Clathrin propeller repeat; [GO:0005198] structural molecule activity; [PTHR10292] CLATHRIN HEAVY CHAIN | 28.77 | 0.8111 |
| 28 |
Mapoly0007s0132
| [KOG2011] Sister chromatid cohesion complex Cohesin, subunit STAG/IRR1/SCC3; [PF08514] STAG domain; [PTHR11199:SF0] SUBFAMILY NOT NAMED; [K06671] cohesin complex subunit SA-1/2; [PTHR11199] STROMAL ANTIGEN | 29.29 | 0.7976 |
| 29 |
Mapoly0026s0045
| [KOG4469] Uncharacterized conserved protein; [PTHR12507:SF3] SUBFAMILY NOT NAMED; [PF08737] Rgp1; [PTHR12507] REDUCED GROWTH PHENOTYPE 1 (RGP1, YEAST)-RELATED | 30.02 | 0.7877 |
| 30 |
Mapoly0085s0035
| [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PTHR23329] TUFTELIN-INTERACTING PROTEIN 11-RELATED; [PF07842] GC-rich sequence DNA-binding factor-like protein; [KOG2184] Tuftelin-interacting protein TIP39, contains G-patch domain; [PF01585] G-patch domain; [PF12457] Tuftelin interacting protein N terminal; [GO:0005634] nucleus; [GO:0003676] nucleic acid binding; [PTHR23329:SF1] TUFTELIN INTERACTING PROTEIN 11; [K13103] tuftelin-interacting protein 11 | 30.40 | 0.8113 |
| 31 |
Mapoly0187s0007
| [PTHR12363] TRANSPORTIN 3 AND IMPORTIN 13; [PF03810] Importin-beta N-terminal domain; [GO:0006886] intracellular protein transport; [GO:0008536] Ran GTPase binding; [KOG2081] Nuclear transport regulator; [PF08389] Exportin 1-like protein | 31.37 | 0.7968 |
| 32 |
Mapoly0093s0032
| [GO:0003677] DNA binding; [PF13891] Potential DNA-binding domain; [GO:0006355] regulation of transcription, DNA-dependent; [PF02362] B3 DNA binding domain; [PTHR31677] FAMILY NOT NAMED; [PF00847] AP2 domain; [GO:0003700] sequence-specific DNA binding transcription factor activity | 32.76 | 0.7989 |
| 33 |
Mapoly0192s0005
| [KOG1082] Histone H3 (Lys9) methyltransferase SUV39H1/Clr4, required for transcriptional silencing; [GO:0005515] protein binding; [PF00856] SET domain; [GO:0008270] zinc ion binding; [PTHR22884] SET DOMAIN PROTEINS; [PF07496] CW-type Zinc Finger | 32.98 | 0.8225 |
| 34 |
Mapoly0095s0011
| [PF10475] Protein of unknown function N-terminal domain (DUF2450); [PTHR12965] VACUOLAR PROTEIN SORTING 54; [KOG2115] Vacuolar sorting protein VPS45; [PTHR12965:SF0] SUBFAMILY NOT NAMED; [GO:0042147] retrograde transport, endosome to Golgi; [PF07928] Vps54-like protein | 33.44 | 0.7950 |
| 35 |
Mapoly0058s0008
| [PF13855] Leucine rich repeat; [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF00069] Protein kinase domain; [PF08263] Leucine rich repeat N-terminal domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE | 37.23 | 0.7333 |
| 36 |
Mapoly0027s0035
| [KOG2006] WD40 repeat protein; [PTHR22746] FAMILY NOT NAMED; [PF07064] RIC1 | 38.18 | 0.7670 |
| 37 |
Mapoly0035s0121
| [PF11935] Domain of unknown function (DUF3453); [K06100] symplekin; [KOG1895] mRNA cleavage and polyadenylation factor II complex, subunit PTA1; [PF12295] Symplekin tight junction protein C terminal; [PTHR15245] SYMPLEKIN-RELATED | 39.33 | 0.8212 |
| 38 |
Mapoly0020s0113
| [GO:0000287] magnesium ion binding; [PTHR24092] FAMILY NOT NAMED; [GO:0005524] ATP binding; [PF12710] haloacid dehalogenase-like hydrolase; [KOG0206] P-type ATPase; [3.6.3.1] Phospholipid-translocating ATPase.; [GO:0000166] nucleotide binding; [GO:0015914] phospholipid transport; [GO:0016021] integral to membrane; [K01530] phospholipid-translocating ATPase [EC:3.6.3.1]; [GO:0046872] metal ion binding; [PF00122] E1-E2 ATPase; [GO:0004012] phospholipid-translocating ATPase activity | 40.30 | 0.8063 |
| 39 |
Mapoly0008s0077
| [PTHR31513] FAMILY NOT NAMED | 42.36 | 0.7937 |
| 40 |
Mapoly0011s0050
| [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR21704] NIPPED-B-LIKE PROTEIN (DELANGIN) SCC2-RELATED; [KOG1020] Sister chromatid cohesion protein SCC2/Nipped-B; [PF12765] HEAT repeat associated with sister chromatid cohesion; [K06672] cohesin loading factor subunit SCC2; [PF12830] Sister chromatid cohesion C-terminus | 42.90 | 0.8119 |
| 41 |
Mapoly0114s0021
| [KOG0446] Vacuolar sorting protein VPS1, dynamin, and related proteins; [PF02212] Dynamin GTPase effector domain; [PF00350] Dynamin family; [PTHR11566] DYNAMIN; [PF00169] PH domain; [GO:0003924] GTPase activity; [GO:0005525] GTP binding; [PF01031] Dynamin central region | 43.71 | 0.7918 |
| 42 |
Mapoly0103s0072
| [KOG1901] Uncharacterized high-glucose-regulated protein; [PTHR12357] YTH (YT521-B HOMOLOGY) DOMAIN-CONTAINING; [PF04146] YT521-B-like domain | 44.41 | 0.7736 |
| 43 |
Mapoly0021s0057
| [PF07303] Occludin homology domain | 45.30 | 0.8183 |
| 44 |
Mapoly0060s0014
| [PF01602] Adaptin N terminal region; [GO:0016192] vesicle-mediated transport; [PTHR11134] ADAPTER-RELATED PROTEIN COMPLEX, BETA SUBUNIT; [PF09066] Beta2-adaptin appendage, C-terminal sub-domain; [KOG1061] Vesicle coat complex AP-1/AP-2/AP-4, beta subunit; [GO:0030131] clathrin adaptor complex; [PTHR11134:SF4] ADAPTER-RELATED PROTEIN COMPLEX 4, BETA SUBUNIT; [GO:0006886] intracellular protein transport; [GO:0030117] membrane coat | 45.37 | 0.6880 |
| 45 |
Mapoly0085s0091
| [GO:0005524] ATP binding; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24361] MITOGEN-ACTIVATED KINASE KINASE KINASE | 46.15 | 0.8050 |
| 46 |
Mapoly0133s0001
| [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24361] MITOGEN-ACTIVATED KINASE KINASE KINASE; [KOG0201] Serine/threonine protein kinase | 46.31 | 0.7863 |
| 47 |
Mapoly0031s0044
| [GO:0004222] metalloendopeptidase activity; [GO:0005524] ATP binding; [PF01434] Peptidase family M41; [KOG0734] AAA+-type ATPase containing the peptidase M41 domain; [PTHR23076] METALLOPROTEASE M41 FTSH; [PF00004] ATPase family associated with various cellular activities (AAA); [GO:0006508] proteolysis | 46.64 | 0.7712 |
| 48 |
Mapoly0121s0051
| [KOG1003] Actin filament-coating protein tropomyosin | 48.50 | 0.8088 |
| 49 |
Mapoly0063s0073
| [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [K14439] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 [EC:3.6.4.12]; [3.6.4.12] DNA helicase.; [PF00271] Helicase conserved C-terminal domain; [KOG0389] SNF2 family DNA-dependent ATPase | 49.13 | 0.7367 |
| 50 |
Mapoly0060s0062
| [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10782] ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; [GO:0008270] zinc ion binding; [PF02891] MIZ/SP-RING zinc finger; [GO:0003676] nucleic acid binding; [PF02037] SAP domain | 49.36 | 0.8070 |
