| 1 |
Mapoly0001s0228
| [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [K00888] phosphatidylinositol 4-kinase [EC:2.7.1.67]; [GO:0046854] phosphatidylinositol phosphorylation; [PTHR10048] PHOSPHATIDYLINOSITOL KINASE; [PF00613] Phosphoinositide 3-kinase family, accessory domain (PIK domain); [PTHR10048:SF15] PHOSPHATIDYLINOSITOL 4-KINASE ALPHA; [PF00454] Phosphatidylinositol 3- and 4-kinase; [2.7.1.67] 1-phosphatidylinositol 4-kinase.; [KOG0902] Phosphatidylinositol 4-kinase; [GO:0048015] phosphatidylinositol-mediated signaling | 2.65 | 0.8865 |
| 2 |
Mapoly0040s0006
| [KOG4205] RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1; [PTHR24011] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 3.46 | 0.8655 |
| 3 |
Mapoly0133s0025
| [PTHR15495] NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006505] GPI anchor metabolic process; [GO:0006886] intracellular protein transport; [PF07819] PGAP1-like protein; [PTHR15495:SF7] SPHINGOSINE-1-PHOSPHATE LYASE-RELATED; [KOG3724] Negative regulator of COPII vesicle formation | 4.24 | 0.8725 |
| 4 |
Mapoly0061s0124
| [PF03177] Non-repetitive/WGA-negative nucleoporin C-terminal; [K14300] nuclear pore complex protein Nup133; [PF08801] Nup133 N terminal like; [PTHR13405] FAMILY NOT NAMED | 5.48 | 0.8786 |
| 5 |
Mapoly0026s0045
| [KOG4469] Uncharacterized conserved protein; [PTHR12507:SF3] SUBFAMILY NOT NAMED; [PF08737] Rgp1; [PTHR12507] REDUCED GROWTH PHENOTYPE 1 (RGP1, YEAST)-RELATED | 6.08 | 0.8409 |
| 6 |
Mapoly0085s0035
| [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PTHR23329] TUFTELIN-INTERACTING PROTEIN 11-RELATED; [PF07842] GC-rich sequence DNA-binding factor-like protein; [KOG2184] Tuftelin-interacting protein TIP39, contains G-patch domain; [PF01585] G-patch domain; [PF12457] Tuftelin interacting protein N terminal; [GO:0005634] nucleus; [GO:0003676] nucleic acid binding; [PTHR23329:SF1] TUFTELIN INTERACTING PROTEIN 11; [K13103] tuftelin-interacting protein 11 | 7.21 | 0.8644 |
| 7 |
Mapoly0072s0074
| [GO:0003723] RNA binding; [PF02854] MIF4G domain; [GO:0005515] protein binding; [KOG2140] Uncharacterized conserved protein; [PTHR18034] CELL CYCLE CONTROL PROTEIN CWF22-RELATED; [PTHR18034:SF3] CELL CYCLE CONTROL PROTEIN CWF22; [K13100] pre-mRNA-splicing factor CWC22; [PF02847] MA3 domain | 7.75 | 0.8859 |
| 8 |
Mapoly0068s0063
| - | 8.31 | 0.8552 |
| 9 |
Mapoly0021s0057
| [PF07303] Occludin homology domain | 8.66 | 0.8828 |
| 10 |
Mapoly0202s0013
| [PF12937] F-box-like; [PF13516] Leucine Rich repeat; [GO:0005515] protein binding; [PTHR23125] F-BOX/LEUCINE RICH REPEAT PROTEIN; [KOG4341] F-box protein containing LRR | 8.83 | 0.8773 |
| 11 |
Mapoly0101s0011
| [GO:0005524] ATP binding; [PTHR19229] ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A (ABCA); [GO:0016887] ATPase activity; [KOG0059] Lipid exporter ABCA1 and related proteins, ABC superfamily; [K05648] ATP-binding cassette, subfamily A (ABC1), member 5; [PF12698] ABC-2 family transporter protein; [PF00005] ABC transporter | 9.49 | 0.8705 |
| 12 |
Mapoly0170s0020
| [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [GO:0005681] spliceosomal complex; [PTHR10887:SF5] INTRON-BINDING PROTEIN AQUARIUS; [PF13086] AAA domain; [GO:0000398] mRNA splicing, via spliceosome; [K12874] intron-binding protein aquarius; [PF13087] AAA domain; [KOG1806] DEAD box containing helicases | 9.59 | 0.8792 |
| 13 |
Mapoly0075s0059
| [GO:0005524] ATP binding; [KOG0296] Angio-associated migratory cell protein (contains WD40 repeats); [PF00069] Protein kinase domain; [PTHR13743] BEIGE/BEACH-RELATED; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PF02138] Beige/BEACH domain; [PF00400] WD domain, G-beta repeat | 9.80 | 0.8733 |
| 14 |
Mapoly0021s0008
| [PTHR12895] FAMILY NOT NAMED; [KOG2225] Proteins containing regions of low-complexity; [PF09742] Dyggve-Melchior-Clausen syndrome protein | 10.20 | 0.8505 |
| 15 |
Mapoly0037s0011
| [PF12842] Domain of unknown function (DUF3819); [PF04054] CCR4-Not complex component, Not1; [PTHR13162:SF8] SUBFAMILY NOT NAMED; [PTHR13162] CCR4-NOT TRANSCRIPTION COMPLEX; [K12604] CCR4-NOT transcription complex subunit 1 | 10.58 | 0.8757 |
| 16 |
Mapoly0005s0057
| [GO:0016787] hydrolase activity; [KOG1386] Nucleoside phosphatase; [PTHR11782] ADENOSINE/GUANOSINE DIPHOSPHATASE; [K01510] apyrase [EC:3.6.1.5]; [3.6.1.5] Apyrase.; [PF01150] GDA1/CD39 (nucleoside phosphatase) family | 11.36 | 0.8341 |
| 17 |
Mapoly0179s0012
| [GO:0016020] membrane; [PF00571] CBS domain; [GO:0006821] chloride transport; [PF00654] Voltage gated chloride channel; [GO:0055085] transmembrane transport; [GO:0005247] voltage-gated chloride channel activity; [GO:0030554] adenyl nucleotide binding; [PTHR11689] CHLORIDE CHANNEL | 13.23 | 0.8440 |
| 18 |
Mapoly0177s0019
| [KOG0149] Predicted RNA-binding protein SEB4 (RRM superfamily); [PF01480] PWI domain; [PTHR23365] POLY-A BINDING PROTEIN 2; [GO:0006397] mRNA processing; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 14.83 | 0.8659 |
| 19 |
Mapoly0031s0044
| [GO:0004222] metalloendopeptidase activity; [GO:0005524] ATP binding; [PF01434] Peptidase family M41; [KOG0734] AAA+-type ATPase containing the peptidase M41 domain; [PTHR23076] METALLOPROTEASE M41 FTSH; [PF00004] ATPase family associated with various cellular activities (AAA); [GO:0006508] proteolysis | 15.49 | 0.8121 |
| 20 |
Mapoly0003s0124
| [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PF13086] AAA domain; [PF13087] AAA domain; [KOG1801] tRNA-splicing endonuclease positive effector (SEN1) | 17.89 | 0.8604 |
| 21 |
Mapoly0016s0170
| [PF13513] HEAT-like repeat; [PF03810] Importin-beta N-terminal domain; [GO:0006886] intracellular protein transport; [GO:0008536] Ran GTPase binding; [PTHR10527] IMPORTIN BETA; [KOG1241] Karyopherin (importin) beta 1; [K14293] importin subunit beta-1 | 18.14 | 0.8305 |
| 22 |
Mapoly0084s0050
| [PTHR10751] GUANYLATE BINDING PROTEIN; [PF02263] Guanylate-binding protein, N-terminal domain; [GO:0003924] GTPase activity; [GO:0005525] GTP binding | 18.71 | 0.8619 |
| 23 |
Mapoly0002s0327
| [K01552] arsenite-transporting ATPase [EC:3.6.3.16]; [KOG0209] P-type ATPase; [GO:0000166] nucleotide binding; [GO:0016021] integral to membrane; [PF00702] haloacid dehalogenase-like hydrolase; [GO:0016887] ATPase activity; [3.6.3.-] Acting on acid anhydrides; catalyzing transmembrane movement of substances.; [GO:0006812] cation transport; [PTHR24093] FAMILY NOT NAMED; [PTHR24093:SF82] ATPASE, P-TYPE, HAD SUPERFAMILY, SUBFAMILY IC, PUTATIVE; [GO:0046872] metal ion binding; [PF00122] E1-E2 ATPase | 18.76 | 0.8334 |
| 24 |
Mapoly0033s0028
| [PTHR21736:SF15] SUBFAMILY NOT NAMED; [PF07227] Protein of unknown function (DUF1423); [PTHR21736] VERNALIZATION-INSENSITIVE PROTEIN 3 | 18.97 | 0.8417 |
| 25 |
Mapoly0138s0007
| [PTHR10233:SF14] TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA; [GO:0044237] cellular metabolic process; [KOG1467] Translation initiation factor 2B, delta subunit (eIF-2Bdelta/GCD2); [PTHR10233] TRANSLATION INITIATION FACTOR EIF-2B; [PF01008] Initiation factor 2 subunit family; [K03680] translation initiation factor eIF-2B delta subunit | 20.00 | 0.8531 |
| 26 |
Mapoly0008s0008
| [K14409] protein SMG7; [PTHR15696] SMG-7 (SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7); [PF10373] Est1 DNA/RNA binding domain; [PF10374] Telomerase activating protein Est1; [PTHR15696:SF0] SUBFAMILY NOT NAMED | 20.78 | 0.8597 |
| 27 |
Mapoly0010s0128
| [KOG4658] Apoptotic ATPase; [PTHR23155] LEUCINE-RICH REPEAT-CONTAINING PROTEIN; [GO:0043531] ADP binding; [PF00931] NB-ARC domain | 22.00 | 0.7929 |
| 28 |
Mapoly0002s0262
| [K07204] regulatory associated protein of mTOR; [PF14538] Raptor N-terminal CASPase like domain; [GO:0005515] protein binding; [GO:0031929] TOR signaling cascade; [PTHR12848] FAMILY NOT NAMED; [GO:0031931] TORC1 complex; [PF00400] WD domain, G-beta repeat; [KOG1517] Guanine nucleotide binding protein MIP1 | 22.18 | 0.8345 |
| 29 |
Mapoly0035s0121
| [PF11935] Domain of unknown function (DUF3453); [K06100] symplekin; [KOG1895] mRNA cleavage and polyadenylation factor II complex, subunit PTA1; [PF12295] Symplekin tight junction protein C terminal; [PTHR15245] SYMPLEKIN-RELATED | 22.58 | 0.8614 |
| 30 |
Mapoly0052s0044
| [KOG0953] Mitochondrial RNA helicase SUV3, DEAD-box superfamily; [PF12513] Mitochondrial degradasome RNA helicase subunit C terminal; [GO:0016817] hydrolase activity, acting on acid anhydrides; [PTHR12131] ATP-DEPENDENT RNA AND DNA HELICASE; [PF00271] Helicase conserved C-terminal domain; [PTHR12131:SF1] ATP-DEPENDENT DNA HELICASE MGPS | 22.91 | 0.8565 |
| 31 |
Mapoly0021s0083
| [PTHR10644:SF2] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 1 (CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 160 KDA SUBUNIT)(CPSF 160 KDA SUBUNIT); [K14401] cleavage and polyadenylation specificity factor subunit 1; [PF10433] Mono-functional DNA-alkylating methyl methanesulfonate N-term; [PF03178] CPSF A subunit region; [GO:0005634] nucleus; [PTHR10644] DNA REPAIR/RNA PROCESSING CPSF FAMILY; [GO:0003676] nucleic acid binding; [KOG1896] mRNA cleavage and polyadenylation factor II complex, subunit CFT1 (CPSF subunit) | 23.24 | 0.7996 |
| 32 |
Mapoly0019s0030
| - | 25.69 | 0.8198 |
| 33 |
Mapoly0048s0072
| [GO:0005524] ATP binding; [GO:0004386] helicase activity; [PTHR18934] ATP-DEPENDENT RNA HELICASE; [KOG0920] ATP-dependent RNA helicase A; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF04408] Helicase associated domain (HA2); [GO:0003676] nucleic acid binding; [PF07717] Oligonucleotide/oligosaccharide-binding (OB)-fold | 25.98 | 0.8504 |
| 34 |
Mapoly0013s0152
| [PTHR12436:SF4] LEUKOCYTE RECEPTOR CLUSTER (LRC) MEMBER 8; [KOG1861] Leucine permease transcriptional regulator; [PTHR12436] 80 KDA MCM3-ASSOCIATED PROTEIN; [PF03399] SAC3/GANP/Nin1/mts3/eIF-3 p25 family | 26.08 | 0.8600 |
| 35 |
Mapoly0176s0001
| [PTHR13793] PHD FINGER PROTEINS; [PF10513] Enhancer of polycomb-like | 26.12 | 0.8557 |
| 36 |
Mapoly0002s0011
| [K13145] integrator complex subunit 8; [PTHR13350] UNCHARACTERIZED | 26.87 | 0.8406 |
| 37 |
Mapoly0029s0081
| [PF12752] SUZ domain; [GO:0003676] nucleic acid binding; [PF01424] R3H domain; [PTHR15672] CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN | 27.35 | 0.7697 |
| 38 |
Mapoly0011s0199
| [PTHR13091:SF0] SUBFAMILY NOT NAMED; [PTHR13091] AMPLIFIED IN BREAST CANCER 2-RELATED; [GO:0000184] nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; [PF10220] Uncharacterized conserved protein (DUF2146) | 27.93 | 0.8577 |
| 39 |
Mapoly0050s0061
| [GO:0016020] membrane; [GO:0005245] voltage-gated calcium channel activity; [PTHR10037] VOLTAGE-GATED CATION CHANNEL (CALCIUM AND SODIUM); [PF00520] Ion transport protein; [GO:0055085] transmembrane transport; [GO:0006811] ion transport; [PTHR10037:SF92] SODIUM CHANNEL PROTEIN TYPE III ALPHA SUBUNIT-RELATED; [GO:0005216] ion channel activity | 28.50 | 0.7645 |
| 40 |
Mapoly0076s0060
| [PTHR12389] ZINC FINGER PROTEIN 294; [PF11793] FANCL C-terminal domain | 28.98 | 0.8500 |
| 41 |
Mapoly0070s0087
| - | 29.22 | 0.8218 |
| 42 |
Mapoly0015s0194
| [PTHR12747] IKAPPAB KINASE COMPLEX-ASSOCIATED PROTEIN; [KOG1920] IkappaB kinase complex, IKAP component; [K11373] elongator complex protein 1; [PF04762] IKI3 family | 29.24 | 0.8590 |
| 43 |
Mapoly0028s0046
| [GO:0005643] nuclear pore; [KOG0845] Nuclear pore complex, Nup98 component (sc Nup145/Nup100/Nup116); [GO:0006810] transport; [PF12110] Nuclear protein 96; [PF04096] Nucleoporin autopeptidase; [PTHR23198] NUCLEOPORIN | 29.39 | 0.8548 |
| 44 |
Mapoly0055s0069
| [PF00782] Dual specificity phosphatase, catalytic domain; [GO:0006470] protein dephosphorylation; [PTHR10159] DUAL SPECIFICITY PROTEIN PHOSPHATASE; [GO:0008138] protein tyrosine/serine/threonine phosphatase activity | 29.73 | 0.8443 |
| 45 |
Mapoly0031s0038
| [PTHR12444:SF3] gb def: c32d5.3.p [caenorhabditis elegans]; [KOG1877] Putative transmembrane protein cmp44E; [PTHR12444] UNCHARACTERIZED | 30.33 | 0.8362 |
| 46 |
Mapoly0138s0035
| [PTHR11851] METALLOPROTEASE | 30.40 | 0.8094 |
| 47 |
Mapoly0097s0085
| [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED | 33.66 | 0.8004 |
| 48 |
Mapoly0060s0062
| [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10782] ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; [GO:0008270] zinc ion binding; [PF02891] MIZ/SP-RING zinc finger; [GO:0003676] nucleic acid binding; [PF02037] SAP domain | 34.32 | 0.8454 |
| 49 |
Mapoly0001s0524
| [K13146] integrator complex subunit 9; [PTHR11203:SF2] INTEGRATOR COMPLEX SUBUNIT 9; [PTHR11203] CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; [GO:0016180] snRNA processing; [PF10996] Beta-Casp domain; [KOG1138] Predicted cleavage and polyadenylation specificity factor (CPSF subunit); [GO:0032039] integrator complex | 35.36 | 0.8295 |
| 50 |
Mapoly0036s0035
| [PTHR23081] RNA POLYMERASE II CTD PHOSPHATASE; [PF03031] NLI interacting factor-like phosphatase; [GO:0005515] protein binding; [PF12738] twin BRCT domain | 36.44 | 0.8095 |
