| 1 |
Mapoly0002s0327
| [K01552] arsenite-transporting ATPase [EC:3.6.3.16]; [KOG0209] P-type ATPase; [GO:0000166] nucleotide binding; [GO:0016021] integral to membrane; [PF00702] haloacid dehalogenase-like hydrolase; [GO:0016887] ATPase activity; [3.6.3.-] Acting on acid anhydrides; catalyzing transmembrane movement of substances.; [GO:0006812] cation transport; [PTHR24093] FAMILY NOT NAMED; [PTHR24093:SF82] ATPASE, P-TYPE, HAD SUPERFAMILY, SUBFAMILY IC, PUTATIVE; [GO:0046872] metal ion binding; [PF00122] E1-E2 ATPase | 1.41 | 0.8560 |
| 2 |
Mapoly0001s0045
| [GO:0072546] ER membrane protein complex; [PTHR21573:SF0] SUBFAMILY NOT NAMED; [PF13360] PQQ-like domain; [KOG2103] Uncharacterized conserved protein; [PF07774] Protein of unknown function (DUF1620); [PTHR21573] UNCHARACTERIZED | 2.83 | 0.7604 |
| 3 |
Mapoly0009s0042
| [KOG1985] Vesicle coat complex COPII, subunit SEC24/subunit SFB2; [PF04815] Sec23/Sec24 helical domain; [GO:0008270] zinc ion binding; [PTHR13803:SF4] gb def: SED5-binding protein 3 (SEC24-related protein 3) (Lethal with SEC13 protein 1); [PF08033] Sec23/Sec24 beta-sandwich domain; [PF04811] Sec23/Sec24 trunk domain; [GO:0006886] intracellular protein transport; [K14007] protein transport protein SEC24; [PF04810] Sec23/Sec24 zinc finger; [GO:0030127] COPII vesicle coat; [PTHR13803] SEC24-RELATED PROTEIN; [GO:0006888] ER to Golgi vesicle-mediated transport | 5.10 | 0.7998 |
| 4 |
Mapoly0022s0125
| [PTHR19876:SF2] COATOMER BETA SUBUNIT; [GO:0016192] vesicle-mediated transport; [KOG0276] Vesicle coat complex COPI, beta' subunit; [GO:0005515] protein binding; [PTHR19876] COATOMER; [PF04053] Coatomer WD associated region; [GO:0006886] intracellular protein transport; [GO:0030117] membrane coat; [GO:0005198] structural molecule activity; [PF00400] WD domain, G-beta repeat | 5.48 | 0.7965 |
| 5 |
Mapoly0005s0185
| [PTHR10811] FRINGE-RELATED; [KOG2246] Galactosyltransferases; [PF04646] Protein of unknown function, DUF604 | 5.83 | 0.7067 |
| 6 |
Mapoly0185s0020
| [PF05450] Nicastrin; [PTHR31826] FAMILY NOT NAMED; [GO:0016485] protein processing; [GO:0016021] integral to membrane; [KOG2526] Predicted aminopeptidases - M20/M25/M40 family | 6.24 | 0.7508 |
| 7 |
Mapoly0003s0232
| [PF04815] Sec23/Sec24 helical domain; [K14006] protein transport protein SEC23; [GO:0008270] zinc ion binding; [PTHR11141:SF2] PROTEIN TRANSPORT PROTEIN SEC23 RELATED; [PF08033] Sec23/Sec24 beta-sandwich domain; [PF04811] Sec23/Sec24 trunk domain; [GO:0006886] intracellular protein transport; [KOG1986] Vesicle coat complex COPII, subunit SEC23; [PF04810] Sec23/Sec24 zinc finger; [GO:0030127] COPII vesicle coat; [PTHR11141] PROTEIN TRANSPORT PROTEIN SEC23; [GO:0006888] ER to Golgi vesicle-mediated transport; [PF00626] Gelsolin repeat | 8.06 | 0.7865 |
| 8 |
Mapoly0103s0007
| [PF03143] Elongation factor Tu C-terminal domain; [PF00009] Elongation factor Tu GTP binding domain; [GO:0003924] GTPase activity; [K03267] G1 to S phase transition protein; [PTHR23115] TRANSLATION FACTOR; [PTHR23115:SF36] EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR GTP-BINDING SUBUNIT (ERF2) (TRANSLATION RELEASE FACTOR 3) (ERF3) (ERF-3); [KOG0459] Polypeptide release factor 3; [GO:0005525] GTP binding; [PF03144] Elongation factor Tu domain 2 | 9.17 | 0.7825 |
| 9 |
Mapoly0029s0118
| [KOG0959] N-arginine dibasic convertase NRD1 and related Zn2+-dependent endopeptidases, insulinase superfamily; [K01411] nardilysin [EC:3.4.24.61]; [PTHR11851] METALLOPROTEASE; [PF05193] Peptidase M16 inactive domain; [PF00675] Insulinase (Peptidase family M16); [3.4.24.61] Nardilysin. | 12.49 | 0.7255 |
| 10 |
Mapoly0004s0190
| [GO:0019867] outer membrane; [PTHR12815] SORTING AND ASSEMBLY MACHINERY (SAM50) PROTEIN; [PF07244] Surface antigen variable number repeat; [KOG2602] Predicted cell surface protein homologous to bacterial outer membrane proteins; [PF01103] Surface antigen | 13.75 | 0.7294 |
| 11 |
Mapoly0125s0017
| [PTHR31515] FAMILY NOT NAMED | 13.93 | 0.6677 |
| 12 |
Mapoly0011s0112
| [GO:0046034] ATP metabolic process; [GO:0005524] ATP binding; [3.6.3.14] H(+)-transporting two-sector ATPase.; [K02145] V-type H+-transporting ATPase subunit A [EC:3.6.3.14]; [PF00006] ATP synthase alpha/beta family, nucleotide-binding domain; [GO:0015992] proton transport; [PTHR15184:SF7] V-TYPE ATP SYNTHASE ALPHA CHAIN; [KOG1352] Vacuolar H+-ATPase V1 sector, subunit A; [GO:0015991] ATP hydrolysis coupled proton transport; [GO:0033178] proton-transporting two-sector ATPase complex, catalytic domain; [GO:0016820] hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; [PF02874] ATP synthase alpha/beta family, beta-barrel domain; [PTHR15184] ATP SYNTHASE; [PF00306] ATP synthase alpha/beta chain, C terminal domain | 14.97 | 0.7445 |
| 13 |
Mapoly0031s0138
| [KOG1931] Putative transmembrane protein; [PTHR13251] EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1; [PF11817] Foie gras liver health family 1; [PF12584] Trafficking protein particle complex subunit 10, TRAPPC10 | 15.36 | 0.7876 |
| 14 |
Mapoly0001s0396
| [PTHR15415] MITOFILIN; [PF09731] Mitochondrial inner membrane protein | 15.87 | 0.6498 |
| 15 |
Mapoly0148s0012
| [PF02136] Nuclear transport factor 2 (NTF2) domain; [PTHR10693] RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [KOG0116] RasGAP SH3 binding protein rasputin, contains NTF2 and RRM domains; [GO:0006810] transport; [GO:0005622] intracellular | 16.09 | 0.7054 |
| 16 |
Mapoly0014s0127
| [PTHR23151] DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED; [2.3.1.61] Dihydrolipoyllysine-residue succinyltransferase.; [KOG0559] Dihydrolipoamide succinyltransferase (2-oxoglutarate dehydrogenase, E2 subunit); [PF00364] Biotin-requiring enzyme; [GO:0008152] metabolic process; [GO:0016746] transferase activity, transferring acyl groups; [PTHR23151:SF8] DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX; [PF00198] 2-oxoacid dehydrogenases acyltransferase (catalytic domain); [K00658] 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] | 16.28 | 0.6884 |
| 17 |
Mapoly0024s0013
| [GO:0016758] transferase activity, transferring hexosyl groups; [PF05637] galactosyl transferase GMA12/MNN10 family; [KOG4748] Subunit of Golgi mannosyltransferase complex; [GO:0016021] integral to membrane; [PTHR31311] FAMILY NOT NAMED | 18.22 | 0.6753 |
| 18 |
Mapoly0006s0233
| [GO:0016021] integral to membrane; [PF02990] Endomembrane protein 70; [KOG1277] Endosomal membrane proteins, EMP70; [PTHR10766:SF14] TRANSMEMBRANE 9 SUPERFAMILY PROTEIN MEMBER 1; [PTHR10766] TRANSMEMBRANE 9 SUPERFAMILY PROTEIN | 18.65 | 0.6731 |
| 19 |
Mapoly0031s0082
| [PTHR12302] EBNA2 BINDING PROTEIN P100; [PF00565] Staphylococcal nuclease homologue; [KOG2039] Transcriptional coactivator p100; [PF00567] Tudor domain; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0003676] nucleic acid binding | 18.84 | 0.6807 |
| 20 |
Mapoly0090s0076
| [GO:0008565] protein transporter activity; [PF02889] Sec63 Brl domain; [PTHR24075:SF0] SUBFAMILY NOT NAMED; [K09540] translocation protein SEC63; [KOG0721] Molecular chaperone (DnaJ superfamily); [PF00226] DnaJ domain; [GO:0031204] posttranslational protein targeting to membrane, translocation; [PTHR24075] FAMILY NOT NAMED | 23.66 | 0.7060 |
| 21 |
Mapoly0005s0083
| [PF01602] Adaptin N terminal region; [GO:0016192] vesicle-mediated transport; [GO:0030126] COPI vesicle coat; [GO:0006886] intracellular protein transport; [GO:0030117] membrane coat; [KOG1078] Vesicle coat complex COPI, gamma subunit; [PF08752] Coatomer gamma subunit appendage platform subdomain; [GO:0005198] structural molecule activity; [PTHR10261] COATOMER SUBUNIT GAMMA | 24.00 | 0.7123 |
| 22 |
Mapoly0003s0171
| [GO:0005086] ARF guanyl-nucleotide exchange factor activity; [PF09324] Domain of unknown function (DUF1981); [PF12783] Guanine nucleotide exchange factor in Golgi transport N-terminal; [KOG0929] Guanine nucleotide exchange factor; [PTHR10663] GUANYL-NUCLEOTIDE EXCHANGE FACTOR; [K13462] guanine nucleotide-exchange factor; [PF01369] Sec7 domain; [GO:0032012] regulation of ARF protein signal transduction | 24.82 | 0.7662 |
| 23 |
Mapoly0103s0072
| [KOG1901] Uncharacterized high-glucose-regulated protein; [PTHR12357] YTH (YT521-B HOMOLOGY) DOMAIN-CONTAINING; [PF04146] YT521-B-like domain | 24.82 | 0.7528 |
| 24 |
Mapoly0003s0069
| [PTHR32219] FAMILY NOT NAMED | 27.93 | 0.6780 |
| 25 |
Mapoly0114s0007
| [KOG0724] Zuotin and related molecular chaperones (DnaJ superfamily), contains DNA-binding domains; [PF00249] Myb-like DNA-binding domain; [GO:0003682] chromatin binding; [PF00226] DnaJ domain; [PTHR24078] DNAJ HOMOLOG SUBFAMILY C MEMBER; [K09522] DnaJ homolog subfamily C member 2 | 28.28 | 0.7256 |
| 26 |
Mapoly0056s0107
| [PF00397] WW domain; [PF02383] SacI homology domain; [PTHR11200] INOSITOL 5-PHOSPHATASE; [GO:0005515] protein binding; [KOG1888] Putative phosphoinositide phosphatase; [GO:0042578] phosphoric ester hydrolase activity | 31.11 | 0.7284 |
| 27 |
Mapoly0025s0013
| [GO:0010468] regulation of gene expression; [GO:0005777] peroxisome; [PTHR14379] LIMKAIN B (LKAP); [PF01936] NYN domain; [PF12872] OST-HTH/LOTUS domain | 31.14 | 0.7539 |
| 28 |
Mapoly0004s0304
| [PF03385] Protein of unknown function, DUF288; [PTHR31362:SF0] SUBFAMILY NOT NAMED; [PTHR31362] FAMILY NOT NAMED | 31.62 | 0.6664 |
| 29 |
Mapoly0153s0030
| [GO:0016651] oxidoreductase activity, acting on NAD(P)H; [GO:0055114] oxidation-reduction process; [PF00384] Molybdopterin oxidoreductase; [1.6.99.3] NADH dehydrogenase.; [PF13510] 2Fe-2S iron-sulfur cluster binding domain; [KOG2282] NADH-ubiquinone oxidoreductase, NDUFS1/75 kDa subunit; [GO:0016491] oxidoreductase activity; [PTHR11615] NITRATE, FROMATE, IRON DEHYDROGENASE; [GO:0051536] iron-sulfur cluster binding; [PF09326] Domain of unknown function (DUF1982); [1.6.5.3] NADH:ubiquinone reductase (H(+)-translocating).; [K03934] NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]; [PF10588] NADH-ubiquinone oxidoreductase-G iron-sulfur binding region | 33.47 | 0.6604 |
| 30 |
Mapoly0036s0102
| [PTHR11216] EH DOMAIN; [GO:0005509] calcium ion binding; [PF13202] EF hand; [PF12763] Cytoskeletal-regulatory complex EF hand | 33.82 | 0.6980 |
| 31 |
Mapoly0025s0051
| [PTHR12984] SCY1-RELATED S/T PROTEIN KINASE-LIKE; [GO:0005524] ATP binding; [PTHR12984:SF3] SCY1(YEAST) PROTEIN KINASE-LIKE; [KOG1243] Protein kinase; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [K08876] SCY1-like | 34.47 | 0.6671 |
| 32 |
Mapoly0156s0024
| [PF08506] Cse1; [PF03810] Importin-beta N-terminal domain; [GO:0005515] protein binding; [KOG1992] Nuclear export receptor CSE1/CAS (importin beta superfamily); [PTHR10997:SF8] IMPORTIN-ALPHA RE-EXPORTER (CHROMOSOME SEGREGATION 1-LIKE PROTEIN); [PF03378] CAS/CSE protein, C-terminus; [GO:0006886] intracellular protein transport; [PTHR10997] IMPORTIN-7, 8, 11; [GO:0008536] Ran GTPase binding | 34.58 | 0.6887 |
| 33 |
Mapoly0032s0093
| [PF02096] 60Kd inner membrane protein; [KOG1239] Inner membrane protein translocase involved in respiratory chain assembly; [K03217] preprotein translocase subunit YidC; [GO:0016021] integral to membrane; [PTHR12428] OXA1; [GO:0051205] protein insertion into membrane | 34.77 | 0.7134 |
| 34 |
Mapoly0121s0027
| [PTHR24089] FAMILY NOT NAMED; [PF00153] Mitochondrial carrier protein; [PTHR24089:SF50] SUBFAMILY NOT NAMED; [KOG0767] Mitochondrial phosphate carrier protein | 34.96 | 0.6943 |
| 35 |
Mapoly0002s0295
| [PF01602] Adaptin N terminal region; [GO:0016192] vesicle-mediated transport; [PTHR11134] ADAPTER-RELATED PROTEIN COMPLEX, BETA SUBUNIT; [PF02883] Adaptin C-terminal domain; [PF09066] Beta2-adaptin appendage, C-terminal sub-domain; [KOG1061] Vesicle coat complex AP-1/AP-2/AP-4, beta subunit; [GO:0030131] clathrin adaptor complex; [GO:0006886] intracellular protein transport; [GO:0030117] membrane coat; [K12392] AP-1 complex subunit beta-1; [PTHR11134:SF3] ADAPTER-RELATED PROTEIN COMPLEX 1, BETA SUBUNIT | 34.99 | 0.7266 |
| 36 |
Mapoly0024s0015
| [GO:0005524] ATP binding; [K03655] ATP-dependent DNA helicase RecG [EC:3.6.4.12]; [3.6.4.12] DNA helicase.; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [KOG0344] ATP-dependent RNA helicase; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PTHR24031:SF50] SUBFAMILY NOT NAMED | 35.41 | 0.6866 |
| 37 |
Mapoly0005s0057
| [GO:0016787] hydrolase activity; [KOG1386] Nucleoside phosphatase; [PTHR11782] ADENOSINE/GUANOSINE DIPHOSPHATASE; [K01510] apyrase [EC:3.6.1.5]; [3.6.1.5] Apyrase.; [PF01150] GDA1/CD39 (nucleoside phosphatase) family | 36.12 | 0.7438 |
| 38 |
Mapoly0014s0172
| - | 37.79 | 0.6891 |
| 39 |
Mapoly0113s0049
| [PTHR32091] FAMILY NOT NAMED | 38.18 | 0.7365 |
| 40 |
Mapoly0101s0011
| [GO:0005524] ATP binding; [PTHR19229] ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A (ABCA); [GO:0016887] ATPase activity; [KOG0059] Lipid exporter ABCA1 and related proteins, ABC superfamily; [K05648] ATP-binding cassette, subfamily A (ABC1), member 5; [PF12698] ABC-2 family transporter protein; [PF00005] ABC transporter | 38.30 | 0.7597 |
| 41 |
Mapoly0022s0120
| [PTHR23323] VACUOLAR MEMBRANE PROTEIN RELATED; [PF00637] Region in Clathrin and VPS; [PF12451] Vacuolar protein sorting protein 11 C terminal; [GO:0016192] vesicle-mediated transport; [GO:0006886] intracellular protein transport; [PTHR23323:SF24] VACUOLAR MEMBRANE PROTEIN PEP5, 11; [KOG2114] Vacuolar assembly/sorting protein PEP5/VPS11 | 38.73 | 0.6796 |
| 42 |
Mapoly0086s0049
| [PF01602] Adaptin N terminal region; [GO:0005737] cytoplasm; [GO:0016192] vesicle-mediated transport; [PF07718] Coatomer beta C-terminal region; [PF14806] Coatomer beta subunit appendage platform; [GO:0030126] COPI vesicle coat; [KOG1058] Vesicle coat complex COPI, beta subunit; [PTHR10635] COATOMER SUBUNIT BETA; [GO:0006886] intracellular protein transport; [GO:0030117] membrane coat; [GO:0005198] structural molecule activity | 39.12 | 0.6949 |
| 43 |
Mapoly0081s0022
| [PF04068] Possible Fer4-like domain in RNase L inhibitor, RLI; [GO:0005524] ATP binding; [PF00037] 4Fe-4S binding domain; [GO:0016887] ATPase activity; [K06174] ATP-binding cassette, sub-family E, member 1; [KOG0063] RNAse L inhibitor, ABC superfamily; [GO:0051536] iron-sulfur cluster binding; [PTHR19248] ATP-BINDING TRANSPORT PROTEIN-RELATED; [PF00005] ABC transporter | 39.80 | 0.7522 |
| 44 |
Mapoly0082s0043
| [GO:0046034] ATP metabolic process; [GO:0005524] ATP binding; [3.6.3.14] H(+)-transporting two-sector ATPase.; [PF00006] ATP synthase alpha/beta family, nucleotide-binding domain; [GO:0015992] proton transport; [K02133] F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]; [KOG1350] F0F1-type ATP synthase, beta subunit; [GO:0033178] proton-transporting two-sector ATPase complex, catalytic domain; [GO:0015991] ATP hydrolysis coupled proton transport; [GO:0016820] hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; [PF02874] ATP synthase alpha/beta family, beta-barrel domain; [PTHR15184] ATP SYNTHASE; [PF00306] ATP synthase alpha/beta chain, C terminal domain | 42.34 | 0.6313 |
| 45 |
Mapoly0119s0040
| [PF03798] TLC domain; [KOG1607] Protein transporter of the TRAM (translocating chain-associating membrane) superfamily; [PTHR12560:SF5] gb def: lagl protein [suberites domuncula]; [GO:0016021] integral to membrane; [PTHR12560] LONGEVITY ASSURANCE FACTOR 1 (LAG1) | 43.07 | 0.5981 |
| 46 |
Mapoly0114s0021
| [KOG0446] Vacuolar sorting protein VPS1, dynamin, and related proteins; [PF02212] Dynamin GTPase effector domain; [PF00350] Dynamin family; [PTHR11566] DYNAMIN; [PF00169] PH domain; [GO:0003924] GTPase activity; [GO:0005525] GTP binding; [PF01031] Dynamin central region | 44.72 | 0.7402 |
| 47 |
Mapoly0045s0097
| [GO:0030130] clathrin coat of trans-Golgi network vesicle; [PF00637] Region in Clathrin and VPS; [GO:0016192] vesicle-mediated transport; [PF09268] Clathrin, heavy-chain linker; [PF13838] Clathrin-H-link; [K04646] clathrin heavy chain; [GO:0006886] intracellular protein transport; [GO:0030132] clathrin coat of coated pit; [KOG0985] Vesicle coat protein clathrin, heavy chain; [PF01394] Clathrin propeller repeat; [GO:0005198] structural molecule activity; [PTHR10292] CLATHRIN HEAVY CHAIN | 44.79 | 0.7375 |
| 48 |
Mapoly0061s0111
| [GO:0016020] membrane; [PF00571] CBS domain; [KOG0474] Cl- channel CLC-7 and related proteins (CLC superfamily); [GO:0006821] chloride transport; [PF00654] Voltage gated chloride channel; [GO:0055085] transmembrane transport; [GO:0005247] voltage-gated chloride channel activity; [GO:0030554] adenyl nucleotide binding; [PTHR11689] CHLORIDE CHANNEL | 44.79 | 0.6859 |
| 49 |
Mapoly0026s0118
| [GO:0016020] membrane; [PF00344] SecY translocase; [GO:0015031] protein transport; [KOG1373] Transport protein Sec61, alpha subunit; [K10956] protein transport protein SEC61 subunit alpha; [PF10559] Plug domain of Sec61p; [PTHR10906] SECY/SEC61-ALPHA FAMILY MEMBER | 50.68 | 0.6153 |
| 50 |
Mapoly0007s0274
| [PTHR21443] CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7; [KOG4182] Uncharacterized conserved protein; [GO:0006886] intracellular protein transport; [PF10191] Golgi complex component 7 (COG7); [GO:0017119] Golgi transport complex | 51.65 | 0.6861 |
