| 1 |
Mapoly0003s0069
| [PTHR32219] FAMILY NOT NAMED | 1.00 | 0.7646 |
| 2 |
Mapoly0016s0186
| [PF00676] Dehydrogenase E1 component; [GO:0055114] oxidation-reduction process; [GO:0006099] tricarboxylic acid cycle; [1.2.4.2] Oxoglutarate dehydrogenase (succinyl-transferring).; [GO:0030976] thiamine pyrophosphate binding; [GO:0008152] metabolic process; [PF02779] Transketolase, pyrimidine binding domain; [K00164] 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]; [GO:0004591] oxoglutarate dehydrogenase (succinyl-transferring) activity; [PTHR23152] 2-OXOGLUTARATE DEHYDROGENASE; [GO:0016624] oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; [KOG0450] 2-oxoglutarate dehydrogenase, E1 subunit | 2.00 | 0.7590 |
| 3 |
Mapoly0153s0030
| [GO:0016651] oxidoreductase activity, acting on NAD(P)H; [GO:0055114] oxidation-reduction process; [PF00384] Molybdopterin oxidoreductase; [1.6.99.3] NADH dehydrogenase.; [PF13510] 2Fe-2S iron-sulfur cluster binding domain; [KOG2282] NADH-ubiquinone oxidoreductase, NDUFS1/75 kDa subunit; [GO:0016491] oxidoreductase activity; [PTHR11615] NITRATE, FROMATE, IRON DEHYDROGENASE; [GO:0051536] iron-sulfur cluster binding; [PF09326] Domain of unknown function (DUF1982); [1.6.5.3] NADH:ubiquinone reductase (H(+)-translocating).; [K03934] NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]; [PF10588] NADH-ubiquinone oxidoreductase-G iron-sulfur binding region | 4.90 | 0.6960 |
| 4 |
Mapoly0063s0010
| [GO:0046912] transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer; [K01647] citrate synthase [EC:2.3.3.1]; [PTHR11739] CITRATE SYNTHASE; [GO:0044262] cellular carbohydrate metabolic process; [2.3.3.1] Citrate (Si)-synthase.; [PF00285] Citrate synthase; [KOG2617] Citrate synthase | 5.48 | 0.6879 |
| 5 |
Mapoly0024s0013
| [GO:0016758] transferase activity, transferring hexosyl groups; [PF05637] galactosyl transferase GMA12/MNN10 family; [KOG4748] Subunit of Golgi mannosyltransferase complex; [GO:0016021] integral to membrane; [PTHR31311] FAMILY NOT NAMED | 5.92 | 0.6661 |
| 6 |
Mapoly0121s0027
| [PTHR24089] FAMILY NOT NAMED; [PF00153] Mitochondrial carrier protein; [PTHR24089:SF50] SUBFAMILY NOT NAMED; [KOG0767] Mitochondrial phosphate carrier protein | 6.24 | 0.7238 |
| 7 |
Mapoly0007s0067
| [K07976] Rab family, other; [GO:0007264] small GTPase mediated signal transduction; [K07874] Ras-related protein Rab-1A; [PTHR24073] FAMILY NOT NAMED; [PF00071] Ras family; [KOG0084] GTPase Rab1/YPT1, small G protein superfamily, and related GTP-binding proteins; [GO:0005525] GTP binding | 11.36 | 0.5701 |
| 8 |
Mapoly0001s0455
| [PF00782] Dual specificity phosphatase, catalytic domain; [PTHR10343] 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT; [GO:0006470] protein dephosphorylation; [GO:0008138] protein tyrosine/serine/threonine phosphatase activity | 14.14 | 0.6234 |
| 9 |
Mapoly0059s0021
| [PTHR24012] FAMILY NOT NAMED; [KOG4205] RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 15.49 | 0.6645 |
| 10 |
Mapoly0022s0120
| [PTHR23323] VACUOLAR MEMBRANE PROTEIN RELATED; [PF00637] Region in Clathrin and VPS; [PF12451] Vacuolar protein sorting protein 11 C terminal; [GO:0016192] vesicle-mediated transport; [GO:0006886] intracellular protein transport; [PTHR23323:SF24] VACUOLAR MEMBRANE PROTEIN PEP5, 11; [KOG2114] Vacuolar assembly/sorting protein PEP5/VPS11 | 16.16 | 0.6621 |
| 11 |
Mapoly0002s0320
| [PF13620] Carboxypeptidase regulatory-like domain; [PTHR23303] CARBOXYPEPTIDASE REGULATORY REGION-CONTAINING; [KOG1948] Metalloproteinase-related collagenase pM5 | 16.28 | 0.6884 |
| 12 |
Mapoly0144s0029
| [GO:0016020] membrane; [PTHR11153] SIDEROFLEXIN; [PF03820] Tricarboxylate carrier; [GO:0055085] transmembrane transport; [GO:0006812] cation transport; [KOG3767] Sideroflexin; [GO:0008324] cation transmembrane transporter activity | 17.49 | 0.5811 |
| 13 |
Mapoly0080s0086
| [PF00264] Common central domain of tyrosinase; [PF12142] Polyphenol oxidase middle domain; [GO:0055114] oxidation-reduction process; [PTHR11474] TYROSINASE; [GO:0016491] oxidoreductase activity; [GO:0008152] metabolic process; [GO:0004097] catechol oxidase activity | 18.65 | 0.6554 |
| 14 |
Mapoly0015s0021
| [GO:0006096] glycolysis; [GO:0016868] intramolecular transferase activity, phosphotransferases; [PTHR11931] PHOSPHOGLYCERATE MUTASE; [KOG0235] Phosphoglycerate mutase; [PF00300] Histidine phosphatase superfamily (branch 1); [GO:0004619] phosphoglycerate mutase activity | 18.97 | 0.5685 |
| 15 |
Mapoly0009s0206
| [3.4.24.64] Mitochondrial processing peptidase.; [KOG0960] Mitochondrial processing peptidase, beta subunit, and related enzymes (insulinase superfamily); [PTHR11851] METALLOPROTEASE; [K01412] mitochondrial processing peptidase [EC:3.4.24.64]; [PF05193] Peptidase M16 inactive domain; [PF00675] Insulinase (Peptidase family M16) | 21.33 | 0.6528 |
| 16 |
Mapoly0029s0002
| [GO:0005524] ATP binding; [PF02359] Cell division protein 48 (CDC48), N-terminal domain; [PF02933] Cell division protein 48 (CDC48), domain 2; [PF00004] ATPase family associated with various cellular activities (AAA); [K13525] transitional endoplasmic reticulum ATPase; [PTHR23077] AAA-FAMILY ATPASE; [KOG0730] AAA+-type ATPase | 22.14 | 0.6595 |
| 17 |
Mapoly0081s0050
| [GO:0000287] magnesium ion binding; [PTHR11902] ENOLASE; [PF03952] Enolase, N-terminal domain; [GO:0004634] phosphopyruvate hydratase activity; [GO:0006096] glycolysis; [PF00113] Enolase, C-terminal TIM barrel domain; [4.2.1.11] Phosphopyruvate hydratase.; [GO:0000015] phosphopyruvate hydratase complex; [K01689] enolase [EC:4.2.1.11]; [KOG2670] Enolase | 22.98 | 0.6023 |
| 18 |
Mapoly0014s0063
| [PTHR23151] DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED; [2.3.1.12] Dihydrolipoyllysine-residue acetyltransferase.; [PF00364] Biotin-requiring enzyme; [KOG0557] Dihydrolipoamide acetyltransferase; [GO:0016746] transferase activity, transferring acyl groups; [GO:0008152] metabolic process; [K00627] pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]; [PF00198] 2-oxoacid dehydrogenases acyltransferase (catalytic domain); [PF02817] e3 binding domain; [PTHR23151:SF9] DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX | 23.69 | 0.6343 |
| 19 |
Mapoly0002s0333
| [1.8.1.7] Glutathione-disulfide reductase.; [GO:0050660] flavin adenine dinucleotide binding; [KOG0405] Pyridine nucleotide-disulphide oxidoreductase; [PTHR22912] DISULFIDE OXIDOREDUCTASE; [GO:0055114] oxidation-reduction process; [GO:0045454] cell redox homeostasis; [PF00070] Pyridine nucleotide-disulphide oxidoreductase; [GO:0016491] oxidoreductase activity; [K00383] glutathione reductase (NADPH) [EC:1.8.1.7]; [PF02852] Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; [PF07992] Pyridine nucleotide-disulphide oxidoreductase | 23.87 | 0.6285 |
| 20 |
Mapoly0078s0049
| - | 26.27 | 0.6032 |
| 21 |
Mapoly0001s0269
| [KOG0254] Predicted transporter (major facilitator superfamily); [PF00083] Sugar (and other) transporter; [GO:0016021] integral to membrane; [GO:0055085] transmembrane transport; [GO:0022857] transmembrane transporter activity; [PTHR24063] FAMILY NOT NAMED | 27.17 | 0.6293 |
| 22 |
Mapoly0056s0114
| [KOG1211] Amidases; [PTHR11895] AMIDASE; [GO:0016884] carbon-nitrogen ligase activity, with glutamine as amido-N-donor; [PF01425] Amidase | 29.17 | 0.5761 |
| 23 |
Mapoly0179s0023
| [PF00571] CBS domain; [PF00564] PB1 domain; [GO:0005515] protein binding; [PTHR13780] AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT; [GO:0030554] adenyl nucleotide binding | 29.46 | 0.5914 |
| 24 |
Mapoly0082s0043
| [GO:0046034] ATP metabolic process; [GO:0005524] ATP binding; [3.6.3.14] H(+)-transporting two-sector ATPase.; [PF00006] ATP synthase alpha/beta family, nucleotide-binding domain; [GO:0015992] proton transport; [K02133] F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]; [KOG1350] F0F1-type ATP synthase, beta subunit; [GO:0033178] proton-transporting two-sector ATPase complex, catalytic domain; [GO:0015991] ATP hydrolysis coupled proton transport; [GO:0016820] hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; [PF02874] ATP synthase alpha/beta family, beta-barrel domain; [PTHR15184] ATP SYNTHASE; [PF00306] ATP synthase alpha/beta chain, C terminal domain | 32.50 | 0.5822 |
| 25 |
Mapoly0096s0015
| [PF01734] Patatin-like phospholipase; [KOG4231] Intracellular membrane-bound Ca2+-independent phospholipase A2; [PF12799] Leucine Rich repeats (2 copies); [PTHR24185] FAMILY NOT NAMED; [GO:0006629] lipid metabolic process | 33.09 | 0.6476 |
| 26 |
Mapoly0011s0112
| [GO:0046034] ATP metabolic process; [GO:0005524] ATP binding; [3.6.3.14] H(+)-transporting two-sector ATPase.; [K02145] V-type H+-transporting ATPase subunit A [EC:3.6.3.14]; [PF00006] ATP synthase alpha/beta family, nucleotide-binding domain; [GO:0015992] proton transport; [PTHR15184:SF7] V-TYPE ATP SYNTHASE ALPHA CHAIN; [KOG1352] Vacuolar H+-ATPase V1 sector, subunit A; [GO:0015991] ATP hydrolysis coupled proton transport; [GO:0033178] proton-transporting two-sector ATPase complex, catalytic domain; [GO:0016820] hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; [PF02874] ATP synthase alpha/beta family, beta-barrel domain; [PTHR15184] ATP SYNTHASE; [PF00306] ATP synthase alpha/beta chain, C terminal domain | 33.82 | 0.6555 |
| 27 |
Mapoly0022s0125
| [PTHR19876:SF2] COATOMER BETA SUBUNIT; [GO:0016192] vesicle-mediated transport; [KOG0276] Vesicle coat complex COPI, beta' subunit; [GO:0005515] protein binding; [PTHR19876] COATOMER; [PF04053] Coatomer WD associated region; [GO:0006886] intracellular protein transport; [GO:0030117] membrane coat; [GO:0005198] structural molecule activity; [PF00400] WD domain, G-beta repeat | 36.47 | 0.6515 |
| 28 |
Mapoly0035s0059
| [KOG0747] Putative NAD+-dependent epimerases; [4.2.1.76] UDP-glucose 4,6-dehydratase.; [PF01370] NAD dependent epimerase/dehydratase family; [GO:0003824] catalytic activity; [K12450] UDP-glucose 4,6-dehydratase [EC:4.2.1.76]; [GO:0009225] nucleotide-sugar metabolic process; [GO:0008460] dTDP-glucose 4,6-dehydratase activity; [GO:0050662] coenzyme binding; [PTHR10366] NAD DEPENDENT EPIMERASE/DEHYDRATASE; [PTHR10366:SF41] DTDP-GLUCOSE 4,6-DEHYDRATASE | 36.74 | 0.6005 |
| 29 |
Mapoly0016s0139
| [K12313] actin, aortic smooth muscle; [PF00022] Actin; [PTHR11937] ACTIN; [KOG0676] Actin and related proteins | 40.35 | 0.6035 |
| 30 |
Mapoly0028s0048
| [GO:0004106] chorismate mutase activity; [5.4.99.5] Chorismate mutase.; [GO:0046417] chorismate metabolic process; [KOG0795] Chorismate mutase; [GO:0009073] aromatic amino acid family biosynthetic process; [PTHR21145:SF0] SUBFAMILY NOT NAMED; [PF01817] Chorismate mutase type II; [K01850] chorismate mutase [EC:5.4.99.5]; [PTHR21145] CHORISMATE MUTASE | 40.53 | 0.5595 |
| 31 |
Mapoly0028s0022
| [3.4.24.64] Mitochondrial processing peptidase.; [PTHR11851] METALLOPROTEASE; [K01412] mitochondrial processing peptidase [EC:3.4.24.64]; [PF05193] Peptidase M16 inactive domain; [PF00675] Insulinase (Peptidase family M16); [KOG2067] Mitochondrial processing peptidase, alpha subunit; [PTHR11851:SF49] MITOCHONDRIAL PROCESSING PEPTIDASE ALPHA SUBUNIT | 40.62 | 0.5860 |
| 32 |
Mapoly0005s0170
| [GO:0016020] membrane; [PF01554] MatE; [GO:0015238] drug transmembrane transporter activity; [GO:0015297] antiporter activity; [GO:0055085] transmembrane transport; [PTHR11206] MULTIDRUG RESISTANCE PROTEIN; [KOG1347] Uncharacterized membrane protein, predicted efflux pump; [GO:0006855] drug transmembrane transport | 40.93 | 0.6014 |
| 33 |
Mapoly0119s0040
| [PF03798] TLC domain; [KOG1607] Protein transporter of the TRAM (translocating chain-associating membrane) superfamily; [PTHR12560:SF5] gb def: lagl protein [suberites domuncula]; [GO:0016021] integral to membrane; [PTHR12560] LONGEVITY ASSURANCE FACTOR 1 (LAG1) | 46.48 | 0.5342 |
| 34 |
Mapoly0002s0067
| [PTHR11632] SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; [PF02910] Fumarate reductase flavoprotein C-term; [PF00890] FAD binding domain; [GO:0055114] oxidation-reduction process; [K00234] succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]; [GO:0016491] oxidoreductase activity; [KOG2403] Succinate dehydrogenase, flavoprotein subunit; [1.3.5.1] Succinate dehydrogenase (ubiquinone). | 46.73 | 0.5707 |
| 35 |
Mapoly0185s0020
| [PF05450] Nicastrin; [PTHR31826] FAMILY NOT NAMED; [GO:0016485] protein processing; [GO:0016021] integral to membrane; [KOG2526] Predicted aminopeptidases - M20/M25/M40 family | 46.96 | 0.5793 |
| 36 |
Mapoly0005s0185
| [PTHR10811] FRINGE-RELATED; [KOG2246] Galactosyltransferases; [PF04646] Protein of unknown function, DUF604 | 50.30 | 0.5667 |
| 37 |
Mapoly0026s0118
| [GO:0016020] membrane; [PF00344] SecY translocase; [GO:0015031] protein transport; [KOG1373] Transport protein Sec61, alpha subunit; [K10956] protein transport protein SEC61 subunit alpha; [PF10559] Plug domain of Sec61p; [PTHR10906] SECY/SEC61-ALPHA FAMILY MEMBER | 50.84 | 0.5546 |
| 38 |
Mapoly0165s0011
| [PTHR10231:SF25] SUBFAMILY NOT NAMED; [GO:0000139] Golgi membrane; [GO:0016021] integral to membrane; [PTHR10231] NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER; [GO:0005351] sugar:hydrogen symporter activity; [GO:0008643] carbohydrate transport; [KOG2234] Predicted UDP-galactose transporter; [PF04142] Nucleotide-sugar transporter | 52.65 | 0.5479 |
| 39 |
Mapoly0014s0172
| - | 53.83 | 0.6227 |
| 40 |
Mapoly0029s0021
| [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF00069] Protein kinase domain; [PF08263] Leucine rich repeat N-terminal domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE | 53.85 | 0.5870 |
| 41 |
Mapoly0248s0004
| [GO:0016020] membrane; [PF01554] MatE; [GO:0015238] drug transmembrane transporter activity; [GO:0015297] antiporter activity; [GO:0055085] transmembrane transport; [PTHR11206] MULTIDRUG RESISTANCE PROTEIN; [KOG1347] Uncharacterized membrane protein, predicted efflux pump; [GO:0006855] drug transmembrane transport | 55.99 | 0.5541 |
| 42 |
Mapoly0004s0190
| [GO:0019867] outer membrane; [PTHR12815] SORTING AND ASSEMBLY MACHINERY (SAM50) PROTEIN; [PF07244] Surface antigen variable number repeat; [KOG2602] Predicted cell surface protein homologous to bacterial outer membrane proteins; [PF01103] Surface antigen | 57.46 | 0.6010 |
| 43 |
Mapoly0009s0042
| [KOG1985] Vesicle coat complex COPII, subunit SEC24/subunit SFB2; [PF04815] Sec23/Sec24 helical domain; [GO:0008270] zinc ion binding; [PTHR13803:SF4] gb def: SED5-binding protein 3 (SEC24-related protein 3) (Lethal with SEC13 protein 1); [PF08033] Sec23/Sec24 beta-sandwich domain; [PF04811] Sec23/Sec24 trunk domain; [GO:0006886] intracellular protein transport; [K14007] protein transport protein SEC24; [PF04810] Sec23/Sec24 zinc finger; [GO:0030127] COPII vesicle coat; [PTHR13803] SEC24-RELATED PROTEIN; [GO:0006888] ER to Golgi vesicle-mediated transport | 59.19 | 0.6367 |
| 44 |
Mapoly0080s0072
| [GO:0004471] malate dehydrogenase (decarboxylating) activity; [PF00390] Malic enzyme, N-terminal domain; [GO:0055114] oxidation-reduction process; [PTHR23406] MALIC ENZYME-RELATED; [1.1.1.39] Malate dehydrogenase (decarboxylating).; [K00028] malate dehydrogenase (decarboxylating) [EC:1.1.1.39]; [PF03949] Malic enzyme, NAD binding domain; [KOG1257] NADP+-dependent malic enzyme; [GO:0051287] NAD binding | 59.97 | 0.5816 |
| 45 |
Mapoly0083s0076
| [PTHR11516:SF25] PYRUVATE DEHYDROGENASE E1 COMPONENT ALPHA SUBUNIT, MITOCHONDRIAL; [1.2.4.1] Pyruvate dehydrogenase (acetyl-transferring).; [PF00676] Dehydrogenase E1 component; [K00161] pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]; [PTHR11516] PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT (BACTERIAL AND ORGANELLAR); [GO:0008152] metabolic process; [KOG0225] Pyruvate dehydrogenase E1, alpha subunit; [GO:0016624] oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | 61.93 | 0.5482 |
| 46 |
Mapoly0028s0042
| [GO:0005515] protein binding; [PF13414] TPR repeat; [KOG4412] 26S proteasome regulatory complex, subunit PSMD10; [PTHR22904:SF145] PROTEIN DIA2; [PF00515] Tetratricopeptide repeat; [PF12796] Ankyrin repeats (3 copies); [PTHR22904] TPR REPEAT CONTAINING PROTEIN | 62.26 | 0.5743 |
| 47 |
Mapoly0077s0009
| [PTHR21461:SF10] gb def: CG12715-PA; [PF01697] Glycosyltransferase family 92; [PTHR21461] UNCHARACTERIZED | 62.26 | 0.5148 |
| 48 |
Mapoly0032s0013
| [GO:0005524] ATP binding; [GO:0016021] integral to membrane; [PTHR24223] FAMILY NOT NAMED; [PF00664] ABC transporter transmembrane region; [GO:0016887] ATPase activity; [GO:0006810] transport; [GO:0055085] transmembrane transport; [KOG0054] Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily; [GO:0042626] ATPase activity, coupled to transmembrane movement of substances; [PF00005] ABC transporter | 62.97 | 0.5495 |
| 49 |
Mapoly0045s0012
| [PTHR23324] SEC14 RELATED PROTEIN | 63.38 | 0.5204 |
| 50 |
Mapoly0052s0094
| [PF01512] Respiratory-chain NADH dehydrogenase 51 Kd subunit; [GO:0016651] oxidoreductase activity, acting on NAD(P)H; [PF10589] NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; [GO:0055114] oxidation-reduction process; [PF10531] SLBB domain; [1.6.99.3] NADH dehydrogenase.; [GO:0051539] 4 iron, 4 sulfur cluster binding; [1.6.5.3] NADH:ubiquinone reductase (H(+)-translocating).; [KOG2658] NADH:ubiquinone oxidoreductase, NDUFV1/51kDa subunit; [PTHR11780] NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 (NDUFV1); [K03942] NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3] | 65.33 | 0.5699 |
