Guide Gene
- Gene ID
- Mapoly0074s0003
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [GO:0003677] DNA binding; [PF12254] DNA polymerase alpha subunit p180 N terminal; [GO:0006260] DNA replication; [GO:0001882] nucleoside binding; [K02320] DNA polymerase alpha subunit A [EC:2.7.7.7]; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0006270] DNA replication initiation; [PF08996] DNA Polymerase alpha zinc finger; [KOG0970] DNA polymerase alpha, catalytic subunit; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0074s0003 [GO:0003677] DNA binding; [PF12254] DNA polymerase alpha subunit p180 N terminal; [GO:0006260] DNA replication; [GO:0001882] nucleoside binding; [K02320] DNA polymerase alpha subunit A [EC:2.7.7.7]; [GO:0000166] nucleotide binding; [2.7.7.7] DNA-directed DNA polymerase.; [PF00136] DNA polymerase family B; [GO:0006270] DNA replication initiation; [PF08996] DNA Polymerase alpha zinc finger; [KOG0970] DNA polymerase alpha, catalytic subunit; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10322] DNA POLYMERASE CATALYTIC SUBUNIT 0.00 1.0000 1 Mapoly0030s0102 [PF08317] Spc7 kinetochore protein 2.65 0.9012 2 Mapoly0118s0038 - 2.83 0.8478 3 Mapoly0004s0300 [GO:0005524] ATP binding; [PTHR11909:SF7] CELL DIVISION CONTROL PROTEIN 7; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K02214] cell division control protein 7 [EC:2.7.11.1]; [KOG1167] Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination; [GO:0006468] protein phosphorylation; [PTHR11909] CASEIN KINASE-RELATED 8.00 0.8663 4 Mapoly0047s0105 [KOG4308] LRR-containing protein; [PTHR10098] RAPSYN-RELATED; [PF13516] Leucine Rich repeat; [PF13414] TPR repeat 8.31 0.8541 5 Mapoly0089s0007 [PF04821] Timeless protein; [PTHR22940:SF4] GB DEF: ARABIDOPSIS THALIANA GENOMIC DNA, CHROMOSOME 5, P1 CLONE:MXC20; [PF05029] Timeless protein C terminal region; [K03155] timeless; [KOG1974] DNA topoisomerase I-interacting protein; [PTHR22940] TIMEOUT/TIMELESS-2 8.49 0.8118 6 Mapoly0005s0005 [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00856] SET domain; [PTHR22884] SET DOMAIN PROTEINS 9.17 0.7907 7 Mapoly0003s0057 [GO:0030915] Smc5-Smc6 complex; [PTHR19306] STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 (SMC5, SMC6); [PF02463] RecF/RecN/SMC N terminal domain; [GO:0006281] DNA repair; [KOG0250] DNA repair protein RAD18 (SMC family protein); [PTHR19306:SF2] STRUCTURAL MAINTENANCE OF CHROMOSOMES 6 SMC6; [GO:0000724] double-strand break repair via homologous recombination 13.42 0.8450 8 Mapoly0053s0106 - 17.66 0.8430 9 Mapoly0025s0108 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity; [PF11995] Domain of unknown function (DUF3490) 21.35 0.7798 10 Mapoly0006s0290 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR10670:SF0] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A; [GO:0000166] nucleotide binding; [GO:0008270] zinc ion binding; [2.7.7.7] DNA-directed DNA polymerase.; [KOG1798] DNA polymerase epsilon, catalytic subunit A; [PF08490] Domain of unknown function (DUF1744); [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF00136] DNA polymerase family B; [GO:0008622] epsilon DNA polymerase complex; [K02324] DNA polymerase epsilon subunit 1 [EC:2.7.7.7]; [GO:0003887] DNA-directed DNA polymerase activity; [PF03104] DNA polymerase family B, exonuclease domain; [PTHR10670] DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A 21.68 0.8290 11 Mapoly0015s0126 [GO:0008641] small protein activating enzyme activity; [GO:0005524] ATP binding; [K10685] ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19]; [KOG2013] SMT3/SUMO-activating complex, catalytic component UBA2; [PF00899] ThiF family; [PF02134] Repeat in ubiquitin-activating (UBA) protein; [6.3.2.19] Ubiquitin--protein ligase.; [PTHR10953] UBIQUITIN-ACTIVATING ENZYME E1; [GO:0003824] catalytic activity; [PF10585] Ubiquitin-activating enzyme active site; [GO:0006464] cellular protein modification process; [PF14732] Ubiquitin/SUMO-activating enzyme ubiquitin-like domain 22.98 0.8046 12 Mapoly0031s0090 [KOG0379] Kelch repeat-containing proteins; [PF13418] Galactose oxidase, central domain; [PTHR23244] KELCH REPEAT DOMAIN; [PF13415] Galactose oxidase, central domain 23.56 0.8185 13 Mapoly0074s0001 [PF03810] Importin-beta N-terminal domain; [PF08767] CRM1 C terminal; [KOG2020] Nuclear transport receptor CRM1/MSN5 (importin beta superfamily); [PTHR11223] EXPORTIN 1/5; [GO:0006886] intracellular protein transport; [PTHR11223:SF2] EXPORTIN 1 (CHROMOSOME REGION MAINTENANCE PROTEIN 1); [K14290] exportin-1; [GO:0008536] Ran GTPase binding; [PF08389] Exportin 1-like protein 23.96 0.7430 14 Mapoly0061s0085 [PF14868] Domain of unknown function (DUF4487) 24.04 0.8141 15 Mapoly0005s0174 [GO:0005524] ATP binding; [KOG0933] Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E); [GO:0007076] mitotic chromosome condensation; [GO:0005515] protein binding; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0000796] condensin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PTHR18937:SF9] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC2; [K06674] structural maintenance of chromosome 2; [PF06470] SMC proteins Flexible Hinge Domain 25.38 0.8349 16 Mapoly0043s0047 [GO:0005515] protein binding; [PF00612] IQ calmodulin-binding motif; [PTHR25069] FAMILY NOT NAMED; [PF00307] Calponin homology (CH) domain 26.08 0.8337 17 Mapoly0209s0008 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF67] DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 26.15 0.8328 18 Mapoly0013s0183 [KOG2739] Leucine-rich acidic nuclear protein; [PF14580] Leucine-rich repeat; [PTHR11375] ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 26.83 0.7744 19 Mapoly0007s0014 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02540] minichromosome maintenance protein 2; [PF12619] Mini-chromosome maintenance protein 2; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PTHR11630:SF44] DNA REPLICATION LICENSING FACTOR MCM2; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [KOG0477] DNA replication licensing factor, MCM2 component 29.95 0.8236 20 Mapoly0147s0033 [PF07738] Sad1 / UNC-like C-terminal; [PTHR12911] SAD1/UNC-84-LIKE PROTEIN-RELATED; [KOG2687] Spindle pole body protein, contains UNC-84 domain 30.50 0.7880 21 Mapoly0030s0020 [KOG2545] Conserved membrane protein; [PTHR13489:SF0] SUBFAMILY NOT NAMED; [PF13615] Putative alanine racemase; [PF09739] Mini-chromosome maintenance replisome factor; [PTHR13489] UNCHARACTERIZED 30.94 0.8253 22 Mapoly0113s0048 [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [KOG1408] WD40 repeat protein; [PF00400] WD domain, G-beta repeat 31.75 0.8248 23 Mapoly0005s0164 [PF13638] PIN domain; [GO:0005515] protein binding; [PTHR22593] FAMILY NOT NAMED; [PF00498] FHA domain 33.94 0.7708 24 Mapoly0108s0041 [PTHR14978:SF0] SUBFAMILY NOT NAMED; [PTHR14978] BETA-CATENIN-LIKE PROTEIN 1 (NUCLEAR ASSOCIATED PROTEIN); [K12864] beta-catenin-like protein 1; [KOG2734] Uncharacterized conserved protein; [PF08216] Catenin-beta-like, Arm-motif containing nuclear 33.99 0.7662 25 Mapoly0011s0202 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain 36.66 0.8219 26 Mapoly0098s0032 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [PF11721] Di-glucose binding within endoplasmic reticulum; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 39.19 0.8174 27 Mapoly0005s0138 - 39.42 0.7757 28 Mapoly0010s0152 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PTHR13561:SF5] DNA REPLICATION REGULATOR DPB11; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 39.69 0.8050 29 Mapoly0102s0001 [K06228] fused [EC:2.7.11.1]; [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR22983:SF6] MAPK KINASE 2-RELATED; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [KOG0598] Ribosomal protein S6 kinase and related proteins; [PF13646] HEAT repeats 39.75 0.8085 30 Mapoly0052s0032 [GO:0006333] chromatin assembly or disassembly; [PF04729] ASF1 like histone chaperone; [K10753] histone chaperone ASF1; [PTHR12040] ANTI-SILENCING PROTEIN 1; [GO:0005634] nucleus 40.02 0.7405 31 Mapoly0033s0057 [2.3.1.-] Transferring groups other than amino-acyl groups.; [PTHR11076:SF1] ESTABLISHMENT OF COHESION 1 (ECO1) HOMOLOG; [PF13880] ESCO1/2 acetyl-transferase; [PF13878] zinc-finger of acetyl-transferase ESCO; [KOG3014] Protein involved in establishing cohesion between sister chromatids during DNA replication; [PTHR11076] DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; [K11268] N-acetyltransferase [EC:2.3.1.-] 42.71 0.8090 32 Mapoly0034s0031 [GO:0007094] mitotic spindle assembly checkpoint; [K06638] mitotic spindle assembly checkpoint protein MAD1; [KOG4593] Mitotic checkpoint protein MAD1; [PTHR23168] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 (MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1); [PF05557] Mitotic checkpoint protein; [PTHR23168:SF0] SUBFAMILY NOT NAMED 42.72 0.7935 33 Mapoly0023s0118 [PTHR12446] TESMIN/TSO1-RELATED; [PF03638] Tesmin/TSO1-like CXC domain, cysteine-rich domain 43.27 0.7967 34 Mapoly0080s0001 [GO:0005515] protein binding; [PTHR15271] CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B; [KOG1009] Chromatin assembly complex 1 subunit B/CAC2 (contains WD40 repeats); [K10751] chromatin assembly factor 1 subunit B; [PF00400] WD domain, G-beta repeat 44.73 0.7998 35 Mapoly0137s0008 [PF06278] Protein of unknown function (DUF1032); [PTHR14324] FAMILY NOT NAMED; [PTHR14324:SF3] SUBFAMILY NOT NAMED; [K11490] condensin-2 complex subunit H2; [KOG2359] Uncharacterized conserved protein 44.99 0.7740 36 Mapoly0005s0051 [GO:0003723] RNA binding; [GO:0000339] RNA cap binding; [GO:0045292] mRNA cis splicing, via spliceosome; [GO:0051028] mRNA transport; [PF02854] MIF4G domain; [GO:0005515] protein binding; [KOG1104] Nuclear cap-binding complex, subunit NCBP1/CBP80; [K12882] nuclear cap-binding protein subunit 1; [GO:0016070] RNA metabolic process; [PTHR12412] CAP BINDING PROTEIN; [GO:0005846] nuclear cap binding complex; [PF09090] MIF4G like; [PF09088] MIF4G like 47.12 0.7899 37 Mapoly0030s0095 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [K10405] kinesin family member C1; [GO:0003777] microtubule motor activity 47.37 0.7696 38 Mapoly0097s0045 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11752] HELICASE SKI2W; [2.7.7.7] DNA-directed DNA polymerase.; [K02349] DNA polymerase theta subunit [EC:2.7.7.7]; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [PF00476] DNA polymerase family A; [GO:0003676] nucleic acid binding; [GO:0003887] DNA-directed DNA polymerase activity; [KOG0950] DNA polymerase theta/eta, DEAD-box superfamily 48.93 0.7588 39 Mapoly0004s0169 [GO:0003677] DNA binding; [GO:0006338] chromatin remodeling; [GO:0005524] ATP binding; [PF09110] HAND; [K11654] SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-]; [GO:0043044] ATP-dependent chromatin remodeling; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [GO:0005634] nucleus; [PTHR10799:SF73] ISWI CHROMATIN-REMODELING COMPLEX ATPASE ISW1; [PF00271] Helicase conserved C-terminal domain; [3.6.4.-] Acting on acid anhydrides; involved in cellular and subcellular movement.; [KOG0385] Chromatin remodeling complex WSTF-ISWI, small subunit; [GO:0003676] nucleic acid binding; [GO:0031491] nucleosome binding; [GO:0016818] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; [PF09111] SLIDE 53.03 0.7807 40 Mapoly0022s0167 [PF12717] non-SMC mitotic condensation complex subunit 1; [PF12922] non-SMC mitotic condensation complex subunit 1, N-term; [GO:0007076] mitotic chromosome condensation; [PTHR14222] CONDENSIN; [KOG0414] Chromosome condensation complex Condensin, subunit D2; [K06677] condensin complex subunit 1 57.86 0.7925 41 Mapoly0036s0107 [K09422] myb proto-oncogene protein, plant; [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding; [PF13921] Myb-like DNA-binding domain 58.69 0.7762 42 Mapoly0020s0135 [PF03941] Inner centromere protein, ARK binding region; [PTHR13142:SF1] INCENP; [KOG1295] Nonsense-mediated decay protein Upf3; [PTHR13142] INNER CENTROMERE PROTEIN 59.48 0.7899 43 Mapoly0098s0043 [PF12717] non-SMC mitotic condensation complex subunit 1; [GO:0007076] mitotic chromosome condensation; [K11491] condensin-2 complex subunit D3; [PTHR14222:SF1] CONDENSIN; [PTHR14222] CONDENSIN 59.70 0.7866 44 Mapoly0188s0017 [KOG4205] RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1; [PTHR24011] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 61.43 0.7250 45 Mapoly0034s0119 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 61.61 0.7929 46 Mapoly0094s0016 [KOG4674] Uncharacterized conserved coiled-coil protein 61.77 0.7827 47 Mapoly0002s0004 [KOG1189] Global transcriptional regulator, cell division control protein; [PF00557] Metallopeptidase family M24; [PF08512] Histone chaperone Rttp106-like; [PTHR13980] CDC68 RELATED; [PF08644] FACT complex subunit (SPT16/CDC68) 62.63 0.7289 48 Mapoly0009s0039 [GO:0030915] Smc5-Smc6 complex; [KOG2866] Uncharacterized conserved protein; [PTHR16140:SF0] SUBFAMILY NOT NAMED; [PTHR16140] UNCHARACTERIZED; [GO:0005634] nucleus; [GO:0006281] DNA repair; [PF08743] Nse4 C-terminal 62.74 0.7868 49 Mapoly0024s0061 [KOG1508] DNA replication factor/protein phosphatase inhibitor SET/SPR-2; [PF00956] Nucleosome assembly protein (NAP); [GO:0005634] nucleus; [GO:0006334] nucleosome assembly; [K11290] template-activating factor I; [PTHR11875] TESTIS-SPECIFIC Y-ENCODED PROTEIN 65.67 0.7701 50 Mapoly0072s0051 [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [KOG0597] Serine-threonine protein kinase FUSED; [GO:0006468] protein phosphorylation 66.09 0.7793 51 Mapoly0032s0119 [GO:0007076] mitotic chromosome condensation; [K06678] condensin complex subunit 3; [GO:0000796] condensin complex; [PTHR14418] CONDENSIN COMPLEX SUBUNIT 3-RELATED; [PF12719] Nuclear condensing complex subunits, C-term domain 66.74 0.7837 52 Mapoly0051s0023 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III 67.71 0.7834 53 Mapoly0001s0472 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [3.6.4.13] RNA helicase.; [GO:0016787] hydrolase activity; [PF04851] Type III restriction enzyme, res subunit; [K10896] fanconi anemia group M protein [EC:3.6.4.13]; [KOG0354] DEAD-box like helicase; [PF00271] Helicase conserved C-terminal domain; [PTHR14025] FAMILY NOT NAMED 68.61 0.7750 54 Mapoly0091s0056 [PF05918] Apoptosis inhibitory protein 5 (API5); [KOG2213] Apoptosis inhibitor 5/fibroblast growth factor 2-interacting factor 2, and related proteins; [PTHR12758] APOPTOSIS INHIBITOR 5-RELATED 70.36 0.7558 55 Mapoly0092s0032 [PTHR22597] POLYCOMB GROUP PROTEIN; [PTHR22597:SF0] SUBFAMILY NOT NAMED; [PF09733] VEFS-Box of polycomb protein 70.60 0.7649 56 Mapoly0016s0083 [PF12214] Cell cycle regulated microtubule associated protein; [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [PTHR14326:SF9] TARGETING PROTEIN FOR XKLP2; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2) 72.43 0.7750 57 Mapoly0034s0112 - 72.75 0.7428 58 Mapoly0060s0012 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [K11498] centromeric protein E; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 72.94 0.7765 59 Mapoly0014s0195 [PTHR10641:SF17] CELL DIVISION CYCLE 5-LIKE PROTEIN; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [PF13921] Myb-like DNA-binding domain; [PF11831] pre-mRNA splicing factor component; [K12860] pre-mRNA-splicing factor CDC5/CEF1 73.48 0.7495 60 Mapoly0015s0045 [KOG0533] RRM motif-containing protein; [PTHR19965] RNA AND EXPORT FACTOR BINDING PROTEIN; [K12881] THO complex subunit 4; [PF13865] C-terminal duplication domain of Friend of PRMT1; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 76.54 0.7380 61 Mapoly0016s0108 [GO:0005524] ATP binding; [K10755] replication factor C subunit 2/4; [KOG0991] Replication factor C, subunit RFC2; [PTHR11669] REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; [PF00004] ATPase family associated with various cellular activities (AAA); [PF08542] Replication factor C C-terminal domain 77.14 0.7427 62 Mapoly0101s0048 [K10752] histone-binding protein RBBP4; [GO:0005515] protein binding; [KOG0264] Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1; [PTHR22850] WD40 REPEAT FAMILY; [PF12265] Histone-binding protein RBBP4 or subunit C of CAF1 complex; [PF00400] WD domain, G-beta repeat 78.41 0.7679 63 Mapoly0070s0034 [KOG0108] mRNA cleavage and polyadenylation factor I complex, subunit RNA15; [PF14327] Hinge domain of cleavage stimulation factor subunit 2; [PTHR23139:SF8] RNA RECOGNITION MOTIF CONTAINING PROTEIN; [PTHR23139] RNA-BINDING PROTEIN; [GO:0003676] nucleic acid binding; [K14407] cleavage stimulation factor subunit 2; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 78.66 0.7396 64 Mapoly0122s0062 [GO:0005524] ATP binding; [PTHR23389] CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; [PF00004] ATPase family associated with various cellular activities (AAA); [K11269] chromosome transmission fidelity protein 18; [KOG1969] DNA replication checkpoint protein CHL12/CTF18 78.77 0.7739 65 Mapoly0042s0105 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 79.32 0.7680 66 Mapoly0007s0134 [KOG3000] Microtubule-binding protein involved in cell cycle control; [GO:0005515] protein binding; [PTHR10623:SF6] MICROTUBULE-ASSOCIATED PROTEIN EB1 (MICROTUBULE PLUS-END BINDING PROTEIN); [PF03271] EB1-like C-terminal motif; [GO:0008017] microtubule binding; [PTHR10623] MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER; [PF00307] Calponin homology (CH) domain 80.85 0.7425 67 Mapoly0113s0037 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [KOG2577] Transcription factor E2F/dimerization partner (TDP); [PTHR12081] TRANSCRIPTION FACTOR E2F 81.00 0.7433 68 Mapoly0051s0002 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 81.17 0.7673 69 Mapoly0001s0044 [PTHR31110] FAMILY NOT NAMED 81.98 0.7582 70 Mapoly0042s0023 [GO:0005524] ATP binding; [2.7.12.1] Dual-specificity kinase.; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [K08866] serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]; [PTHR22974] MIXED LINEAGE PROTEIN KINASE 82.46 0.7697 71 Mapoly0057s0017 - 83.76 0.7612 72 Mapoly0061s0044 [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2) 85.17 0.7605 73 Mapoly0096s0020 [GO:0005524] ATP binding; [PF02359] Cell division protein 48 (CDC48), N-terminal domain; [PF02933] Cell division protein 48 (CDC48), domain 2; [PF00004] ATPase family associated with various cellular activities (AAA); [K13525] transitional endoplasmic reticulum ATPase; [PTHR23077] AAA-FAMILY ATPASE; [KOG0730] AAA+-type ATPase 85.95 0.7429 74 Mapoly0001s0188 - 86.08 0.7646 75 Mapoly0042s0049 - 87.29 0.7617 76 Mapoly0060s0105 [PTHR24012] FAMILY NOT NAMED; [KOG4207] Predicted splicing factor, SR protein superfamily; [GO:0008270] zinc ion binding; [PF00098] Zinc knuckle; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 87.46 0.7404 77 Mapoly0061s0120 [PTHR13269] UNCHARACTERIZED; [PTHR13269:SF6] SUBFAMILY NOT NAMED; [PF09531] Nucleoporin protein Ndc1-Nup 87.55 0.7509 78 Mapoly0044s0021 [KOG0275] Conserved WD40 repeat-containing protein; [PTHR22848] WD40 REPEAT PROTEIN; [GO:0005515] protein binding; [K13111] WD40 repeat-containing protein SMU1; [PF00400] WD domain, G-beta repeat 90.27 0.7358 79 Mapoly0012s0102 [PTHR23365] POLY-A BINDING PROTEIN 2; [K14396] polyadenylate-binding protein 2; [KOG4209] Splicing factor RNPS1, SR protein superfamily; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 92.79 0.7168 80 Mapoly0102s0024 [GO:0006355] regulation of transcription, DNA-dependent; [PF14443] DBC1; [KOG3227] Calcium-responsive transcription coactivator; [PTHR14304] P30 DBC PROTEIN 93.13 0.7626 81 Mapoly0024s0112 [GO:0005643] nuclear pore; [KOG1964] Nuclear pore complex, rNup107 component (sc Nup84); [PTHR13003] NUP107-RELATED; [GO:0006810] transport; [PF04121] Nuclear pore protein 84 / 107; [K14301] nuclear pore complex protein Nup107 93.72 0.7513 82 Mapoly0027s0041 [GO:0005643] nuclear pore; [PTHR13437] NUCLEOPORIN P58/P45 (NUCLEOPORIN-LIKE PROTEIN 1); [GO:0006913] nucleocytoplasmic transport 94.10 0.7464 83 Mapoly0078s0017 - 94.20 0.7633 84 Mapoly0060s0056 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 95.21 0.7407 85 Mapoly0063s0094 - 95.81 0.6973 86 Mapoly0009s0056 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [PF08311] Mad3/BUB1 homology region 1; [K02178] checkpoint serine/threonine-protein kinase [EC:2.7.11.1]; [KOG1166] Mitotic checkpoint serine/threonine protein kinase; [PTHR14030] MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 96.16 0.7534 87 Mapoly0029s0012 [GO:0005524] ATP binding; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [KOG0329] ATP-dependent RNA helicase; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding 96.16 0.7546 88 Mapoly0095s0052 [PF08839] DNA replication factor CDT1 like 96.75 0.7435 89 Mapoly0037s0093 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG4280] Kinesin-like protein; [PTHR24115:SF87] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [PF12711] Kinesin motor; [GO:0003777] microtubule motor activity 97.44 0.7379 90 Mapoly0043s0056 [K12831] splicing factor 3B subunit 4; [KOG0131] Splicing factor 3b, subunit 4; [PTHR24011] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 99.66 0.7117 91 Mapoly0042s0086 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [K08737] DNA mismatch repair protein MSH6; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PTHR11361:SF31] MUTS HOMOLOG 6, MSH6; [PF01624] MutS domain I; [PF05192] MutS domain III; [PF05190] MutS family domain IV 100.35 0.7374 92 Mapoly0043s0064 [PF10979] Protein of unknown function (DUF2786) 102.13 0.7530 93 Mapoly0043s0112 [PTHR21780] UNCHARACTERIZED; [KOG4670] Uncharacterized conserved membrane protein; [PTHR21780:SF0] SUBFAMILY NOT NAMED; [PF09786] Cytochrome B561, N terminal 103.88 0.7520 94 Mapoly0118s0005 [GO:0008233] peptidase activity; [3.4.22.49] Separase.; [K02365] separase [EC:3.4.22.49]; [GO:0005634] nucleus; [PF03568] Peptidase family C50; [GO:0006508] proteolysis; [PTHR12792] EXTRA SPINDLE POLES 1-RELATED 103.88 0.7473 95 Mapoly0082s0057 [PTHR32282] FAMILY NOT NAMED; [PF00912] Transglycosylase; [PTHR32282:SF0] SUBFAMILY NOT NAMED; [PF00905] Penicillin binding protein transpeptidase domain; [GO:0008658] penicillin binding 104.50 0.6787 96 Mapoly0061s0078 [KOG1361] Predicted hydrolase involved in interstrand cross-link repair; [PTHR23240] DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; [PF12706] Beta-lactamase superfamily domain; [PF07522] DNA repair metallo-beta-lactamase; [PF00536] SAM domain (Sterile alpha motif) 108.00 0.7271 97 Mapoly0001s0076 [PF00225] Kinesin motor domain; [GO:0007018] microtubule-based movement; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0008017] microtubule binding; [KOG4280] Kinesin-like protein; [PF06548] Kinesin-related; [GO:0003777] microtubule motor activity; [GO:0005871] kinesin complex 108.89 0.7456 98 Mapoly0078s0012 [GO:0006396] RNA processing; [PTHR11061] RNA M5U METHYLTRANSFERASE FAMILY; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [GO:0008173] RNA methyltransferase activity; [PF05958] tRNA (Uracil-5-)-methyltransferase; [GO:0046872] metal ion binding; [KOG2187] tRNA uracil-5-methyltransferase and related tRNA-modifying enzymes 109.63 0.7182 99 Mapoly0033s0098 [PTHR16047] RFWD3 PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PTHR16047:SF7] RFWD3 PROTEIN-RELATED; [KOG1645] RING-finger-containing E3 ubiquitin ligase 110.35 0.7335 100 Mapoly0001s0105 [K02541] minichromosome maintenance protein 3; [KOG0479] DNA replication licensing factor, MCM3 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11630:SF46] DNA REPLICATION LICENSING FACTOR MCM3; [PF00493] MCM2/3/5 family; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 111.13 0.7562 101 Mapoly0003s0063 [GO:0005524] ATP binding; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24361:SF129] MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE; [GO:0006468] protein phosphorylation; [PTHR24361] MITOGEN-ACTIVATED KINASE KINASE KINASE 112.16 0.7506 102 Mapoly0158s0006 - 112.69 0.7331 103 Mapoly0081s0071 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [PF00628] PHD-finger; [GO:0005515] protein binding; [PF12738] twin BRCT domain; [GO:0046872] metal ion binding 112.78 0.7439 104 Mapoly0103s0079 [GO:0003677] DNA binding; [PTHR13763:SF0] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0005634] nucleus; [GO:0006281] DNA repair; [GO:0004842] ubiquitin-protein ligase activity; [KOG4362] Transcriptional regulator BRCA1; [PTHR13763] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; [PF13771] PHD-like zinc-binding domain 115.74 0.7545 105 Mapoly0055s0120 - 115.93 0.7228 106 Mapoly0007s0003 [GO:0005515] protein binding; [PTHR19918:SF8] gb def: Meiosis-specific APC/C activator protein AMA1 (Activator of meiotic APC/C protei; [KOG0305] Anaphase promoting complex, Cdc20, Cdh1, and Ama1 subunits; [K03363] cell division cycle 20, cofactor of APC complex; [PTHR19918] CELL DIVISION CYCLE 20 (CDC20) (FIZZY)-RELATED; [PF00400] WD domain, G-beta repeat 117.03 0.7288 107 Mapoly0051s0085 [KOG2267] Eukaryotic-type DNA primase, large subunit; [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10537] DNA PRIMASE LARGE SUBUNIT; [K02685] DNA primase large subunit [EC:2.7.7.-]; [PF04104] Eukaryotic and archaeal DNA primase, large subunit; [2.7.7.-] Nucleotidyltransferases. 117.17 0.7374 108 Mapoly0028s0066 [GO:0005524] ATP binding; [KOG1112] Ribonucleotide reductase, alpha subunit; [GO:0006260] DNA replication; [GO:0055114] oxidation-reduction process; [GO:0004748] ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; [PF00317] Ribonucleotide reductase, all-alpha domain; [PTHR11573] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN; [PTHR11573:SF6] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN; [PF02867] Ribonucleotide reductase, barrel domain; [1.17.4.1] Ribonucleoside-diphosphate reductase.; [K10807] ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]; [PF03477] ATP cone domain 119.65 0.7303 109 Mapoly0089s0046 [K06688] ubiquitin-conjugating enzyme E2 C [EC:6.3.2.19]; [PTHR24067:SF44] UBIQUITIN-CONJUGATING ENZYME E2 C; [PTHR24067] UBIQUITIN-CONJUGATING ENZYME E2; [GO:0016881] acid-amino acid ligase activity; [6.3.2.19] Ubiquitin--protein ligase.; [PF00179] Ubiquitin-conjugating enzyme; [KOG0421] Ubiquitin-protein ligase 125.14 0.7091 110 Mapoly0074s0020 - 126.11 0.5435 111 Mapoly0189s0011 [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain 126.96 0.7294 112 Mapoly0105s0060 [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [K12898] heterogeneous nuclear ribonucleoprotein F/H; [KOG4211] Splicing factor hnRNP-F and related RNA-binding proteins; [PTHR13976] HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED 128.23 0.7407 113 Mapoly0154s0005 [PTHR22852] LETHAL(2)DENTICLELESS PROTEIN (RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN); [KOG0265] U5 snRNP-specific protein-like factor and related proteins; [K11790] denticleless; [GO:0005515] protein binding; [PF00400] WD domain, G-beta repeat 128.33 0.7396 114 Mapoly0109s0019 [KOG1375] Beta tubulin; [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [K07375] tubulin beta; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [GO:0005525] GTP binding 128.55 0.6940 115 Mapoly0050s0134 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PF01751] Toprim domain; [PTHR10169] DNA TOPOISOMERASE/GYRASE; [GO:0006265] DNA topological change; [GO:0003918] DNA topoisomerase type II (ATP-hydrolyzing) activity; [PF00521] DNA gyrase/topoisomerase IV, subunit A; [KOG0355] DNA topoisomerase type II; [5.99.1.3] DNA topoisomerase (ATP-hydrolyzing).; [PF00204] DNA gyrase B; [K03164] DNA topoisomerase II [EC:5.99.1.3] 128.70 0.7327 116 Mapoly0039s0109 [KOG0553] TPR repeat-containing protein; [PF14559] Tetratricopeptide repeat; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR 129.90 0.7045 117 Mapoly0007s0100 [PTHR15828] CYTOKINE RECEPTOR-LIKE FACTOR 3 130.90 0.7215 118 Mapoly0087s0035 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [PTHR24115:SF105] SUBFAMILY NOT NAMED; [KOG0243] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 130.90 0.6893 119 Mapoly0025s0128 [PF00134] Cyclin, N-terminal domain; [PTHR10177] CYCLINE; [PF02984] Cyclin, C-terminal domain; [GO:0005634] nucleus; [PTHR10177:SF49] CYCLIN-A; [KOG0654] G2/Mitotic-specific cyclin A; [K06627] cyclin A 131.04 0.7280 120 Mapoly0034s0011 [PF09133] SANTA (SANT Associated) 133.18 0.7339 121 Mapoly0076s0085 [KOG0005] Ubiquitin-like protein; [GO:0005515] protein binding; [PF00240] Ubiquitin family; [PTHR10666:SF57] UBIQUITIN / RIBOSOMAL PROTEIN S27A.1 (PUTATIVE UNCHARACTERIZED PROTEIN) (OS01G03; [PTHR10666] UBIQUITIN 135.10 0.7198 122 Mapoly0036s0151 [PF00268] Ribonucleotide reductase, small chain; [GO:0055114] oxidation-reduction process; [K10808] ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]; [PTHR23409] RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN; [1.17.4.1] Ribonucleoside-diphosphate reductase.; [KOG1567] Ribonucleotide reductase, beta subunit; [GO:0009186] deoxyribonucleoside diphosphate metabolic process 135.48 0.7102 123 Mapoly0070s0053 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF09382] RQC domain; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [K10901] bloom syndrome protein [EC:3.6.4.12]; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 135.55 0.7291 124 Mapoly0008s0081 [PTHR21286] NUCLEAR PORE COMPLEX PROTEIN NUP160; [K14303] nuclear pore complex protein Nup160; [KOG4521] Nuclear pore complex, Nup160 component; [PF11715] Nucleoporin Nup120/160 137.37 0.7317 125 Mapoly0013s0040 [GO:0005524] ATP binding; [KOG0359] Chaperonin complex component, TCP-1 zeta subunit (CCT6); [GO:0044267] cellular protein metabolic process; [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family 137.49 0.7089 126 Mapoly0001s0378 [PTHR32086] FAMILY NOT NAMED; [K10891] fanconi anemia group D2 protein; [GO:0006281] DNA repair; [KOG4712] Uncharacterized conserved protein; [PF14631] Fanconi anaemia protein FancD2 nuclease 137.51 0.7213 127 Mapoly0065s0078 [PTHR24115:SF171] SUBFAMILY NOT NAMED; [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [K10403] kinesin family member 22; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 139.14 0.7270 128 Mapoly0025s0127 - 139.19 0.7163 129 Mapoly0010s0010 [GO:0005643] nuclear pore; [PF13874] Nucleoporin complex subunit 54; [PTHR13000] NUCLEOPORIN P54; [KOG3091] Nuclear pore complex, p54 component (sc Nup57) 140.40 0.7117 130 Mapoly0001s0304 [KOG0543] FKBP-type peptidyl-prolyl cis-trans isomerase; [PTHR10516] PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; [GO:0005515] protein binding; [PF13414] TPR repeat; [GO:0006457] protein folding; [K01802] peptidylprolyl isomerase [EC:5.2.1.8]; [PF00254] FKBP-type peptidyl-prolyl cis-trans isomerase; [5.2.1.8] Peptidylprolyl isomerase.; [PF00515] Tetratricopeptide repeat 140.55 0.5762 131 Mapoly0031s0066 [PTHR12087:SF0] SUBFAMILY NOT NAMED; [KOG2228] Origin recognition complex, subunit 4; [PF13191] AAA ATPase domain; [PF14629] Origin recognition complex (ORC) subunit 4 C-terminus; [PTHR12087] ORIGIN RECOGNITION COMPLEX SUBUNIT 4; [K02606] origin recognition complex subunit 4 140.71 0.5760 132 Mapoly0080s0039 [PTHR15081] NUCLEAR AUTOANTIGENIC SPERM PROTEIN (NASP)-RELATED; [PF13414] TPR repeat; [PF10516] SHNi-TPR 143.44 0.7123 133 Mapoly0081s0073 - 143.47 0.7167 134 Mapoly0013s0006 [GO:0008270] zinc ion binding; [PF13589] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PTHR23336] ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3.; [PF07496] CW-type Zinc Finger 144.35 0.6986 135 Mapoly0039s0120 [KOG1805] DNA replication helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PTHR10887:SF14] DNA2-LIKE HELICASE; [3.6.4.12] DNA helicase.; [PF13086] AAA domain; [GO:0033567] DNA replication, Okazaki fragment processing; [PF01930] Domain of unknown function DUF83; [GO:0017108] 5'-flap endonuclease activity; [GO:0043142] single-stranded DNA-dependent ATPase activity; [PF13087] AAA domain; [PF08696] DNA replication factor Dna2; [K10742] DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12] 146.33 0.6947 136 Mapoly0032s0034 - 148.03 0.7110 137 Mapoly0097s0064 [PTHR13710:SF1] ROTHMUND-THOMSON SYNDROME DNA HELICASE RECQ4; [GO:0005524] ATP binding; [PF11719] DNA replication and checkpoint protein; [K10730] ATP-dependent DNA helicase Q4 [EC:3.6.4.12]; [KOG0351] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [PF00271] Helicase conserved C-terminal domain; [GO:0003676] nucleic acid binding; [PF02037] SAP domain 148.33 0.7215 138 Mapoly0052s0095 [GO:0005643] nuclear pore; [PTHR31344:SF0] SUBFAMILY NOT NAMED; [K14310] nuclear pore complex protein Nup205; [PF11894] Protein of unknown function (DUF3414); [PTHR31344] FAMILY NOT NAMED; [KOG1835] Uncharacterized conserved protein 149.36 0.6966 139 Mapoly0001s0406 [GO:0000922] spindle pole; [KOG2000] Gamma-tubulin complex, DGRIP91/SPC98 component; [PF04130] Spc97 / Spc98 family; [GO:0005856] cytoskeleton; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [GO:0007020] microtubule nucleation; [PTHR19302:SF14] GAMMA-TUBULIN COMPLEX COMPONENT 3 (GCP-3) 149.97 0.6856 140 Mapoly0075s0032 [GO:0003677] DNA binding; [GO:0006275] regulation of DNA replication; [GO:0030337] DNA polymerase processivity factor activity; [PTHR11352] PROLIFERATING CELL NUCLEAR ANTIGEN; [PF00705] Proliferating cell nuclear antigen, N-terminal domain; [K04802] proliferating cell nuclear antigen; [KOG1636] DNA polymerase delta processivity factor (proliferating cell nuclear antigen); [PF02747] Proliferating cell nuclear antigen, C-terminal domain 149.97 0.7004 141 Mapoly0113s0005 - 149.98 0.7071 142 Mapoly0138s0046 [KOG1803] DNA helicase; [PTHR10887] DNA2/NAM7 HELICASE FAMILY; [PF13086] AAA domain; [PF13087] AAA domain 150.13 0.7184 143 Mapoly0108s0031 [GO:0005524] ATP binding; [K04499] RuvB-like protein 1 (pontin 52); [KOG1942] DNA helicase, TBP-interacting protein; [PF06068] TIP49 C-terminus; [GO:0043141] ATP-dependent 5'-3' DNA helicase activity; [GO:0003678] DNA helicase activity; [PTHR11093] RUVB-RELATED REPTIN AND PONTIN 150.98 0.7066 144 Mapoly0020s0107 [KOG4626] O-linked N-acetylglucosamine transferase OGT; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF13432] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat; [PF13844] Glycosyl transferase family 41; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR 151.99 0.6987 145 Mapoly0179s0001 [PTHR10994] RETICULON; [PF02453] Reticulon; [KOG1792] Reticulon 153.31 0.7222 146 Mapoly0030s0009 [PF00505] HMG (high mobility group) box; [KOG0526] Nucleosome-binding factor SPN, POB3 subunit; [PF03531] Structure-specific recognition protein (SSRP1); [PTHR13711:SF39] SUBFAMILY NOT NAMED; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN; [PF08512] Histone chaperone Rttp106-like; [K09272] structure-specific recognition protein 1 156.10 0.7115 147 Mapoly0051s0070 [PF13920] Zinc finger, C3HC4 type (RING finger) 158.11 0.5784 148 Mapoly0053s0080 [GO:0006396] RNA processing; [GO:0003723] RNA binding; [PF12230] Pre-mRNA splicing factor PRP21 like protein; [GO:0005515] protein binding; [PTHR15316:SF1] SPLICEOSOME ASSOCIATED PROTEIN 114; [PF00240] Ubiquitin family; [K12825] splicing factor 3A subunit 1; [PTHR15316] SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED; [PF01805] Surp module; [KOG0007] Splicing factor 3a, subunit 1 159.15 0.7000 149 Mapoly0085s0026 [PF00533] BRCA1 C Terminus (BRCT) domain; [PTHR23196] PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN 160.84 0.7115 150 Mapoly0045s0042 [KOG2475] CDC45 (cell division cycle 45)-like protein; [GO:0006270] DNA replication initiation; [PF02724] CDC45-like protein; [PTHR10507:SF0] CDC45-RELATED PROTEIN; [PTHR10507] CDC45-RELATED PROTEIN; [K06628] cell division control protein 45 162.85 0.7180 151 Mapoly0026s0077 [GO:0016773] phosphotransferase activity, alcohol group as acceptor; [PF02259] FAT domain; [GO:0005515] protein binding; [2.7.11.1] Non-specific serine/threonine protein kinase.; [PF08064] UME (NUC010) domain; [PF00454] Phosphatidylinositol 3- and 4-kinase; [K06640] ataxia telangiectasia and Rad3 related [EC:2.7.11.1]; [GO:0004674] protein serine/threonine kinase activity; [PF02260] FATC domain; [PTHR11139] ATAXIA TELANGIECTASIA MUTATED (ATM)-RELATED; [KOG0890] Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination 162.92 0.6957 152 Mapoly0133s0013 [PF00628] PHD-finger; [GO:0005515] protein binding; [PTHR10615] HISTONE ACETYLTRANSFERASE; [PF00856] SET domain 164.94 0.7173 153 Mapoly0045s0061 [KOG1081] Transcription factor NSD1 and related SET domain proteins; [GO:0005515] protein binding; [PF00856] SET domain; [PTHR22884] SET DOMAIN PROTEINS 165.55 0.7052 154 Mapoly0005s0161 [GO:0003677] DNA binding; [PTHR13451:SF0] SUBFAMILY NOT NAMED; [3.1.22.-] Endodeoxyribonucleases producing other than 5'-phosphomonoesters.; [K08991] crossover junction endonuclease MUS81 [EC:3.1.22.-]; [PTHR13451] CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81; [GO:0004518] nuclease activity; [PF02732] ERCC4 domain 165.90 0.6683 155 Mapoly0022s0165 [GO:0003714] transcription corepressor activity; [PF12070] Protein of unknown function (DUF3550/UPF0682); [PTHR21243] FAMILY NOT NAMED; [GO:0006351] transcription, DNA-dependent 167.55 0.5810 156 Mapoly0019s0119 - 167.75 0.7100 157 Mapoly0005s0208 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [KOG0244] Kinesin-like protein; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [K10395] kinesin family member 4/7/21/27; [GO:0003777] microtubule motor activity 170.25 0.6967 158 Mapoly0011s0125 [PTHR19375] HEAT SHOCK PROTEIN 70KDA; [K03283] heat shock 70kDa protein 1/8; [KOG0100] Molecular chaperones GRP78/BiP/KAR2, HSP70 superfamily; [PF00012] Hsp70 protein 170.85 0.6248 159 Mapoly0023s0006 - 171.85 0.5788 160 Mapoly0120s0004 [PF00488] MutS domain V; [GO:0005524] ATP binding; [K08735] DNA mismatch repair protein MSH2; [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PTHR11361:SF35] MUTS HOMOLOG 2, MSH2; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III; [KOG0219] Mismatch repair ATPase MSH2 (MutS family); [PF05190] MutS family domain IV 172.65 0.7013 161 Mapoly0119s0016 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [KOG0480] DNA replication licensing factor, MCM6 component; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630:SF43] DNA REPLICATION LICENSING FACTOR MCM6; [K02542] minichromosome maintenance protein 6; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain 174.62 0.7132 162 Mapoly0073s0027 [GO:0005524] ATP binding; [K07760] cyclin-dependent kinase [EC:2.7.11.22]; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [KOG0594] Protein kinase PCTAIRE and related kinases; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 176.72 0.6900 163 Mapoly0001s0170 - 177.00 0.6826 164 Mapoly0197s0017 [PTHR10751] GUANYLATE BINDING PROTEIN; [KOG1003] Actin filament-coating protein tropomyosin; [PTHR10751:SF2] GUANYLATE BINDING PROTEIN; [PF02263] Guanylate-binding protein, N-terminal domain; [GO:0003924] GTPase activity; [GO:0005525] GTP binding; [PF02841] Guanylate-binding protein, C-terminal domain 179.93 0.6514 165 Mapoly0046s0026 [PF10250] GDP-fucose protein O-fucosyltransferase; [PTHR31933] FAMILY NOT NAMED 180.67 0.6445 166 Mapoly0035s0137 [GO:0005643] nuclear pore; [PTHR10350:SF6] NUCLEOPORIN 155; [PF03177] Non-repetitive/WGA-negative nucleoporin C-terminal; [K14312] nuclear pore complex protein Nup155; [KOG1900] Nuclear pore complex, Nup155 component (D Nup154, sc Nup157/Nup170); [GO:0006913] nucleocytoplasmic transport; [PF08801] Nup133 N terminal like; [GO:0017056] structural constituent of nuclear pore; [PTHR10350] NUCLEAR PORE COMPLEX PROTEIN NUP155 181.08 0.7175 167 Mapoly0001s0446 - 181.47 0.6803 168 Mapoly0067s0089 [GO:0005515] protein binding; [PF00498] FHA domain; [PTHR23308] NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 182.43 0.6950 169 Mapoly0064s0110 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PTHR13394] ORIGIN RECOGNITION COMPLEX SUBUNIT 6; [PF05460] Origin recognition complex subunit 6 (ORC6); [GO:0005664] nuclear origin of replication recognition complex; [K02608] origin recognition complex subunit 6; [PTHR13394:SF0] SUBFAMILY NOT NAMED; [KOG4557] Origin recognition complex, subunit 6 183.21 0.7079 170 Mapoly0211s0017 [PTHR32387] FAMILY NOT NAMED 183.52 0.6133 171 Mapoly0126s0040 [PTHR11062] EXOSTOSIN (HEPARAN SULFATE GLYCOSYLTRANSFERASE)-RELATED; [KOG1021] Acetylglucosaminyltransferase EXT1/exostosin 1; [PF03016] Exostosin family 184.72 0.6287 172 Mapoly0004s0096 [K11548] kinetochore protein Nuf2; [GO:0007067] mitosis; [PTHR21650] MEMBRALIN/KINETOCHORE PROTEIN NUF2; [PF03800] Nuf2 family; [KOG4438] Centromere-associated protein NUF2; [GO:0000775] chromosome, centromeric region; [PTHR21650:SF2] KINETOCHORE PROTEIN NUF2 185.38 0.7011 173 Mapoly0011s0047 [PTHR12972] DOWNSTREAM NEIGHBOR OF SON 185.42 0.6728 174 Mapoly0003s0120 [GO:0003677] DNA binding; [PTHR12708:SF0] SUBFAMILY NOT NAMED; [GO:0006260] DNA replication; [PF12213] DNA polymerases epsilon N terminal; [2.7.7.7] DNA-directed DNA polymerase.; [PTHR12708] DNA POLYMERASE EPSILON SUBUNIT B; [KOG3818] DNA polymerase epsilon, subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [GO:0003887] DNA-directed DNA polymerase activity; [K02325] DNA polymerase epsilon subunit 2 [EC:2.7.7.7] 185.93 0.6795 175 Mapoly0052s0086 [PF05641] Agenet domain; [PTHR31917] FAMILY NOT NAMED 186.41 0.7008 176 Mapoly0130s0046 [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF14493] Helix-turn-helix domain; [PF09382] RQC domain; [K10900] werner syndrome ATP-dependent helicase [EC:3.6.4.12]; [KOG0353] ATP-dependent DNA helicase; [3.6.4.12] DNA helicase.; [PTHR13710] DNA HELICASE RECQ FAMILY MEMBER; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [GO:0005622] intracellular; [GO:0003676] nucleic acid binding; [GO:0043140] ATP-dependent 3'-5' DNA helicase activity; [PF00570] HRDC domain 186.56 0.6970 177 Mapoly0001s0525 [K14408] cleavage stimulation factor subunit 3; [GO:0006397] mRNA processing; [GO:0005634] nucleus; [KOG1914] mRNA cleavage and polyadenylation factor I complex, subunit RNA14; [PTHR19980] RNA CLEAVAGE STIMULATION FACTOR; [PF05843] Suppressor of forked protein (Suf) 187.08 0.7057 178 Mapoly0001s0011 [K02219] cyclin-dependent kinase regulatory subunit CKS1; [KOG3484] Cyclin-dependent protein kinase CDC28, regulatory subunit CKS1, and related proteins; [PF01111] Cyclin-dependent kinase regulatory subunit; [GO:0016538] cyclin-dependent protein serine/threonine kinase regulator activity; [GO:0007049] cell cycle; [PTHR23415] CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 191.00 0.6730 179 Mapoly0053s0008 - 193.39 0.6736 180 Mapoly0067s0068 [KOG2266] Chromatin-associated protein Dek and related proteins, contains SAP DNA binding domain; [PTHR13468:SF1] DEK ONCOGENE; [PF08766] DEK C terminal domain; [PTHR13468] DEK PROTEIN 196.07 0.6903 181 Mapoly0042s0123 [K12875] apoptotic chromatin condensation inducer in the nucleus; [GO:0003676] nucleic acid binding; [PTHR14127] APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; [PF02037] SAP domain 196.20 0.7054 182 Mapoly0159s0029 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [PTHR12081:SF7] TRANSCRIPTION FACTOR E2F; [PTHR12081] TRANSCRIPTION FACTOR E2F 197.51 0.6469 183 Mapoly0009s0121 [GO:0005524] ATP binding; [GO:0044267] cellular protein metabolic process; [KOG0364] Chaperonin complex component, TCP-1 gamma subunit (CCT3); [PTHR11353] CHAPERONIN; [PF00118] TCP-1/cpn60 chaperonin family; [GO:0006457] protein folding; [GO:0051082] unfolded protein binding 199.04 0.6596 184 Mapoly0021s0007 [PTHR11851:SF85] AGR251CP; [3.4.24.56] Insulysin.; [KOG0959] N-arginine dibasic convertase NRD1 and related Zn2+-dependent endopeptidases, insulinase superfamily; [K01408] insulysin [EC:3.4.24.56]; [PTHR11851] METALLOPROTEASE; [PF05193] Peptidase M16 inactive domain; [PF00675] Insulinase (Peptidase family M16) 199.45 0.6384 185 Mapoly0076s0033 [PF10444] Nbl1 / Borealin N terminal 200.45 0.6817 186 Mapoly0038s0027 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PTHR10629:SF11] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF12047] Cytosine specific DNA methyltransferase replication foci domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 201.50 0.6672 187 Mapoly0105s0040 [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [GO:0005516] calmodulin binding; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2); [PF07839] Plant calmodulin-binding domain 201.98 0.6681 188 Mapoly0029s0045 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0243] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [PF12711] Kinesin motor; [GO:0003777] microtubule motor activity; [K10400] kinesin family member 15 202.46 0.6430 189 Mapoly0005s0010 - 202.99 0.6635 190 Mapoly0002s0133 [GO:0007076] mitotic chromosome condensation; [PTHR13108] FAMILY NOT NAMED; [PF05786] Condensin complex subunit 2; [KOG2328] Chromosome condensation complex Condensin, subunit H; [GO:0000796] condensin complex; [K06676] condensin complex subunit 2 203.31 0.6901 191 Mapoly0061s0010 [GO:0006269] DNA replication, synthesis of RNA primer; [GO:0003896] DNA primase activity; [PTHR10536] DNA PRIMASE SMALL SUBUNIT; [KOG2851] Eukaryotic-type DNA primase, catalytic (small) subunit; [K02684] DNA primase small subunit [EC:2.7.7.-]; [2.7.7.-] Nucleotidyltransferases.; [PF01896] Eukaryotic and archaeal DNA primase small subunit 203.47 0.6928 192 Mapoly0039s0061 [PF12612] Tubulin folding cofactor D C terminal; [KOG1943] Beta-tubulin folding cofactor D; [PTHR12658] BETA-TUBULIN COFACTOR D 203.88 0.6684 193 Mapoly0140s0032 [PTHR12748] ORIGIN RECOGNITION COMPLEX SUBUNIT 3; [PTHR12748:SF0] SUBFAMILY NOT NAMED; [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02605] origin recognition complex subunit 3; [PF07034] Origin recognition complex (ORC) subunit 3 N-terminus; [KOG2538] Origin recognition complex, subunit 3; [GO:0005664] nuclear origin of replication recognition complex; [PF02178] AT hook motif 204.45 0.6978 194 Mapoly0019s0032 - 204.72 0.6892 195 Mapoly0033s0145 - 205.03 0.6739 196 Mapoly0055s0064 - 206.04 0.6955 197 Mapoly0026s0138 [KOG0381] HMG box-containing protein; [PF00505] HMG (high mobility group) box; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN 207.91 0.6665 198 Mapoly0036s0123 [GO:0000922] spindle pole; [PTHR19302:SF13] GAMMA-TUBULIN COMPLEX COMPONENT 2 (GCP-2); [PF04130] Spc97 / Spc98 family; [GO:0005815] microtubule organizing center; [GO:0000226] microtubule cytoskeleton organization; [PTHR19302] GAMMA TUBULIN COMPLEX PROTEIN; [KOG2001] Gamma-tubulin complex, DGRIP84/SPC97 component 208.24 0.7000 199 Mapoly0004s0306 [KOG1871] Ubiquitin-specific protease; [3.1.2.15] Ubiquitin thiolesterase.; [PF00443] Ubiquitin carboxyl-terminal hydrolase; [GO:0006511] ubiquitin-dependent protein catabolic process; [K11841] ubiquitin carboxyl-terminal hydrolase 10 [EC:3.1.2.15]; [PTHR24006] FAMILY NOT NAMED 208.45 0.5795 200 Mapoly0051s0073 [PF14675] FANCI solenoid 1; [PTHR21818:SF0] SUBFAMILY NOT NAMED; [PF14680] FANCI helical domain 2; [KOG4553] Uncharacterized conserved protein; [K10895] fanconi anemia group I protein; [PF14679] FANCI helical domain 1; [GO:0006281] DNA repair; [PF14678] FANCI solenoid 4; [PTHR21818] BC025462 PROTEIN; [PF14676] FANCI solenoid 2 209.02 0.6859