Guide Gene
- Gene ID
- Mapoly0099s0061
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- [KOG1187] Serine/threonine protein kinase; [PF07714] Protein tyrosine kinase; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0099s0061 [KOG1187] Serine/threonine protein kinase; [PF07714] Protein tyrosine kinase; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 0.00 1.0000 1 Mapoly0031s0037 [PTHR21230] VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED; [PF03908] Sec20; [K08494] novel plant SNARE 2.83 0.7675 2 Mapoly0005s0208 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [KOG0244] Kinesin-like protein; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [K10395] kinesin family member 4/7/21/27; [GO:0003777] microtubule motor activity 4.58 0.8339 3 Mapoly0077s0034 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 4.90 0.7628 4 Mapoly0005s0016 - 7.62 0.7863 5 Mapoly0190s0010 [GO:0008762] UDP-N-acetylmuramate dehydrogenase activity; [PTHR10801:SF0] 24-DEHYDROCHOLESTEROL REDUCTASE; [GO:0050660] flavin adenine dinucleotide binding; [KOG1262] FAD-binding protein DIMINUTO; [K09828] delta24-sterol reductase [EC:1.3.1.72]; [GO:0055114] oxidation-reduction process; [1.3.1.72] Delta(24)-sterol reductase.; [GO:0016491] oxidoreductase activity; [PTHR10801] 24-DEHYDROCHOLESTEROL REDUCTASE; [PF01565] FAD binding domain 7.75 0.7644 6 Mapoly0099s0047 [PTHR23054] UNCHARACTERIZED; [PF04784] Protein of unknown function, DUF547; [PF14389] Leucine-zipper of ternary complex factor MIP1 10.68 0.7251 7 Mapoly0003s0015 - 13.86 0.7161 8 Mapoly0060s0031 - 13.86 0.7554 9 Mapoly0081s0019 [PF00083] Sugar (and other) transporter; [GO:0016021] integral to membrane; [GO:0055085] transmembrane transport; [KOG0255] Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily); [PTHR24064] FAMILY NOT NAMED; [GO:0022857] transmembrane transporter activity 16.12 0.6746 10 Mapoly0016s0083 [PF12214] Cell cycle regulated microtubule associated protein; [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [PTHR14326:SF9] TARGETING PROTEIN FOR XKLP2; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2) 19.21 0.7743 11 Mapoly0021s0156 [GO:0016020] membrane; [GO:0005524] ATP binding; [PF08370] Plant PDR ABC transporter associated; [GO:0016887] ATPase activity; [PTHR19241] ATP-BINDING CASSETTE TRANSPORTER; [PF01061] ABC-2 type transporter; [PF14510] ABC-transporter extracellular N-terminal; [KOG0065] Pleiotropic drug resistance proteins (PDR1-15), ABC superfamily; [PF00005] ABC transporter 21.82 0.7350 12 Mapoly0159s0028 [PTHR10992] ALPHA/BETA HYDROLASE FOLD-CONTAINING PROTEIN; [PF13837] Myb/SANT-like DNA-binding domain; [PF12697] Alpha/beta hydrolase family; [PTHR10992:SF252] SUBFAMILY NOT NAMED 26.72 0.7047 13 Mapoly0076s0085 [KOG0005] Ubiquitin-like protein; [GO:0005515] protein binding; [PF00240] Ubiquitin family; [PTHR10666:SF57] UBIQUITIN / RIBOSOMAL PROTEIN S27A.1 (PUTATIVE UNCHARACTERIZED PROTEIN) (OS01G03; [PTHR10666] UBIQUITIN 27.11 0.7596 14 Mapoly0158s0006 - 33.00 0.7387 15 Mapoly0115s0027 [PTHR31084:SF0] SUBFAMILY NOT NAMED; [PF14498] Glycosyl hydrolase family 65, N-terminal domain; [PTHR31084] FAMILY NOT NAMED 34.99 0.6665 16 Mapoly0179s0003 [PTHR19444] UNC-93 RELATED; [PF05978] Ion channel regulatory protein UNC-93; [KOG3097] Predicted membrane protein 35.50 0.6496 17 Mapoly0008s0246 [KOG3303] Predicted alpha-helical protein, potentially involved in replication/repair; [PTHR12914:SF2] PARTNER OF SLD5; [PF05916] GINS complex protein; [PTHR12914] PARTNER OF SLD5; [K10732] GINS complex subunit 1 36.51 0.6966 18 Mapoly0041s0110 [KOG3043] Predicted hydrolase related to dienelactone hydrolase; [GO:0016787] hydrolase activity; [PTHR17630] DIENELACTONE HYDROLASE; [PF01738] Dienelactone hydrolase family 37.70 0.6926 19 Mapoly0101s0065 [PF12330] Domain of unknown function (DUF3635); [PTHR24419] INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE; [KOG2464] Serine/threonine kinase (haspin family) 38.88 0.7226 20 Mapoly0028s0139 [PTHR11200] INOSITOL 5-PHOSPHATASE; [PF03372] Endonuclease/Exonuclease/phosphatase family; [KOG0565] Inositol polyphosphate 5-phosphatase and related proteins 39.12 0.6506 21 Mapoly0022s0139 [PTHR31867] FAMILY NOT NAMED; [PF03330] Rare lipoprotein A (RlpA)-like double-psi beta-barrel; [PF01357] Pollen allergen 41.57 0.6481 22 Mapoly0007s0080 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 42.99 0.7370 23 Mapoly0003s0088 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 43.13 0.7340 24 Mapoly0025s0002 [2.6.1.44] Alanine--glyoxylate transaminase.; [KOG1404] Alanine-glyoxylate aminotransferase AGT2; [PTHR11986] AMINOTRANSFERASE CLASS III; [GO:0030170] pyridoxal phosphate binding; [2.6.1.40] (R)-3-amino-2-methylpropionate--pyruvate transaminase.; [K00827] alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase [EC:2.6.1.44 2.6.1.40]; [GO:0008483] transaminase activity; [PF00202] Aminotransferase class-III 43.68 0.6492 25 Mapoly0029s0045 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0243] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [PF12711] Kinesin motor; [GO:0003777] microtubule motor activity; [K10400] kinesin family member 15 44.70 0.7123 26 Mapoly0098s0032 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [PF11721] Di-glucose binding within endoplasmic reticulum; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 45.72 0.7373 27 Mapoly0003s0063 [GO:0005524] ATP binding; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24361:SF129] MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE; [GO:0006468] protein phosphorylation; [PTHR24361] MITOGEN-ACTIVATED KINASE KINASE KINASE 46.86 0.7367 28 Mapoly0109s0044 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [PF04057] Replication factor-A protein 1, N-terminal domain; [GO:0005634] nucleus; [KOG0851] Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins; [PF08646] Replication factor-A C terminal domain; [GO:0003676] nucleic acid binding; [K07466] replication factor A1; [PTHR23273] REPLICATION FACTOR A 1, RFA1; [PF01336] OB-fold nucleic acid binding domain 46.99 0.7181 29 Mapoly0036s0107 [K09422] myb proto-oncogene protein, plant; [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding; [PF13921] Myb-like DNA-binding domain 48.66 0.7340 30 Mapoly0179s0001 [PTHR10994] RETICULON; [PF02453] Reticulon; [KOG1792] Reticulon 49.04 0.7365 31 Mapoly0184s0017 [PTHR19353:SF10] DELTA-5 FATTY ACID DESATURASE; [PTHR19353] FATTY ACID DESATURASE 2; [GO:0020037] heme binding; [PF00487] Fatty acid desaturase; [KOG4232] Delta 6-fatty acid desaturase/delta-8 sphingolipid desaturase; [PF00173] Cytochrome b5-like Heme/Steroid binding domain; [GO:0006629] lipid metabolic process 51.65 0.6446 32 Mapoly0051s0092 [GO:0007264] small GTPase mediated signal transduction; [K07975] Rho family, other; [PTHR24072] RHO FAMILY GTPASE; [KOG0393] Ras-related small GTPase, Rho type; [PF00071] Ras family; [GO:0005525] GTP binding 52.65 0.6971 33 Mapoly0042s0007 [GO:0003677] DNA binding; [K02213] cell division control protein 6; [KOG2227] Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase; [PF13401] AAA domain; [PF01429] Methyl-CpG binding domain; [GO:0005634] nucleus; [PF09079] CDC6, C terminal; [PTHR10763] CELL DIVISION CONTROL PROTEIN 6-RELATED 53.48 0.7226 34 Mapoly0046s0055 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [KOG1374] Gamma tubulin; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [GO:0031122] cytoplasmic microtubule organization; [PTHR11588:SF7] TUBULIN GAMMA CHAIN; [K10389] tubulin gamma; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0007020] microtubule nucleation; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0000930] gamma-tubulin complex; [GO:0043234] protein complex; [GO:0005525] GTP binding 56.23 0.7075 35 Mapoly0127s0051 [GO:0045454] cell redox homeostasis; [5.3.4.1] Protein disulfide-isomerase.; [PF13848] Thioredoxin-like domain; [KOG0190] Protein disulfide isomerase (prolyl 4-hydroxylase beta subunit); [PF00085] Thioredoxin; [K09580] protein disulfide-isomerase A1 [EC:5.3.4.1]; [PTHR18929] PROTEIN DISULFIDE ISOMERASE 58.40 0.5432 36 Mapoly0015s0106 [PF04577] Protein of unknown function (DUF563); [PTHR20961] GLYCOSYLTRANSFERASE; [GO:0016757] transferase activity, transferring glycosyl groups; [PTHR20961:SF0] SUBFAMILY NOT NAMED 58.66 0.6470 37 Mapoly0113s0048 [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [KOG1408] WD40 repeat protein; [PF00400] WD domain, G-beta repeat 62.26 0.7276 38 Mapoly0074s0062 [PF00011] Hsp20/alpha crystallin family 62.61 0.5656 39 Mapoly0058s0053 [PF04791] LMBR1-like membrane protein; [K14617] LMBR1 domain-containing protein 1; [PTHR31652] FAMILY NOT NAMED 62.83 0.6553 40 Mapoly0105s0040 [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [GO:0005516] calmodulin binding; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2); [PF07839] Plant calmodulin-binding domain 64.16 0.7118 41 Mapoly0034s0119 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 64.20 0.7251 42 Mapoly0006s0267 - 64.81 0.6439 43 Mapoly0053s0016 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 64.99 0.7195 44 Mapoly0006s0009 [KOG4172] Predicted E3 ubiquitin ligase; [PF00097] Zinc finger, C3HC4 type (RING finger); [GO:0046872] metal ion binding; [PTHR23328] UNCHARACTERIZED 65.04 0.7094 45 Mapoly0057s0064 [PF06273] Plant specific eukaryotic initiation factor 4B; [PTHR32091] FAMILY NOT NAMED 66.39 0.5856 46 Mapoly0001s0140 [PF01852] START domain; [PTHR12136] STEROIDOGENIC ACUTE REGULATORY PROTEIN (STAR); [GO:0008289] lipid binding; [PF07059] Protein of unknown function (DUF1336) 68.41 0.6576 47 Mapoly0081s0071 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PF00097] Zinc finger, C3HC4 type (RING finger); [PF00628] PHD-finger; [GO:0005515] protein binding; [PF12738] twin BRCT domain; [GO:0046872] metal ion binding 71.39 0.7152 48 Mapoly0159s0029 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [PTHR12081:SF7] TRANSCRIPTION FACTOR E2F; [PTHR12081] TRANSCRIPTION FACTOR E2F 72.99 0.6939 49 Mapoly0003s0259 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PTHR24420:SF474] SUBFAMILY NOT NAMED; [PF00069] Protein kinase domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 73.05 0.7095 50 Mapoly0026s0138 [KOG0381] HMG box-containing protein; [PF00505] HMG (high mobility group) box; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN 76.11 0.7062 51 Mapoly0006s0242 - 77.07 0.7061 52 Mapoly0006s0287 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02209] minichromosome maintenance protein 5 (cell division control protein 46); [PTHR11630:SF42] DNA REPLICATION LICENSING FACTOR MCM5; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain; [KOG0481] DNA replication licensing factor, MCM5 component 77.30 0.7159 53 Mapoly0051s0086 [PF05859] Mis12 protein; [GO:0007067] mitosis; [GO:0005634] nucleus; [GO:0000775] chromosome, centromeric region; [GO:0007049] cell cycle 80.70 0.7011 54 Mapoly0005s0010 - 83.24 0.6979 55 Mapoly0051s0075 [GO:0003723] RNA binding; [KOG2190] PolyC-binding proteins alphaCP-1 and related KH domain proteins; [PTHR10288] KH DOMAIN CONTAINING RNA BINDING PROTEIN; [PTHR10288:SF102] ANKYRIN REPEAT-CONTAINING PROTEIN; [PF00013] KH domain 83.71 0.6651 56 Mapoly0061s0044 [GO:0005874] microtubule; [GO:0007067] mitosis; [GO:0005819] spindle; [PTHR14326] TARGETING PROTEIN FOR XKLP2; [PF06886] Targeting protein for Xklp2 (TPX2) 88.26 0.7003 57 Mapoly0020s0157 - 88.87 0.6259 58 Mapoly0114s0009 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [PF00514] Armadillo/beta-catenin-like repeat; [GO:0005515] protein binding; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [KOG0240] Kinesin (SMY1 subfamily); [GO:0008017] microtubule binding; [PTHR24115:SF221] SUBFAMILY NOT NAMED; [GO:0003777] microtubule motor activity 89.39 0.6780 59 Mapoly0014s0033 [KOG4285] Mitotic phosphoprotein; [PTHR21527] FAMILY NOT NAMED; [K14313] nuclear pore complex protein Nup53; [PF05172] Nup53/35/40-type RNA recognition motif 90.83 0.6712 60 Mapoly0022s0167 [PF12717] non-SMC mitotic condensation complex subunit 1; [PF12922] non-SMC mitotic condensation complex subunit 1, N-term; [GO:0007076] mitotic chromosome condensation; [PTHR14222] CONDENSIN; [KOG0414] Chromosome condensation complex Condensin, subunit D2; [K06677] condensin complex subunit 1 91.19 0.7013 61 Mapoly0102s0001 [K06228] fused [EC:2.7.11.1]; [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR22983:SF6] MAPK KINASE 2-RELATED; [2.7.11.1] Non-specific serine/threonine protein kinase.; [GO:0006468] protein phosphorylation; [KOG0598] Ribosomal protein S6 kinase and related proteins; [PF13646] HEAT repeats 91.65 0.7019 62 Mapoly0001s0076 [PF00225] Kinesin motor domain; [GO:0007018] microtubule-based movement; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0008017] microtubule binding; [KOG4280] Kinesin-like protein; [PF06548] Kinesin-related; [GO:0003777] microtubule motor activity; [GO:0005871] kinesin complex 92.09 0.6981 63 Mapoly0060s0012 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [K11498] centromeric protein E; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 96.34 0.6990 64 Mapoly0048s0068 [KOG0653] Cyclin B and related kinase-activating proteins; [PF00134] Cyclin, N-terminal domain; [PTHR10177] CYCLINE; [PF02984] Cyclin, C-terminal domain; [GO:0005634] nucleus; [K05868] cyclin B 96.71 0.6847 65 Mapoly0050s0134 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PF02518] Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [PF01751] Toprim domain; [PTHR10169] DNA TOPOISOMERASE/GYRASE; [GO:0006265] DNA topological change; [GO:0003918] DNA topoisomerase type II (ATP-hydrolyzing) activity; [PF00521] DNA gyrase/topoisomerase IV, subunit A; [KOG0355] DNA topoisomerase type II; [5.99.1.3] DNA topoisomerase (ATP-hydrolyzing).; [PF00204] DNA gyrase B; [K03164] DNA topoisomerase II [EC:5.99.1.3] 96.75 0.6944 66 Mapoly0053s0008 - 98.08 0.6894 67 Mapoly0051s0002 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 98.16 0.6940 68 Mapoly0045s0075 - 103.29 0.6587 69 Mapoly0046s0087 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PTHR24420:SF145] SUBFAMILY NOT NAMED; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 103.49 0.6241 70 Mapoly0019s0185 [GO:0005506] iron ion binding; [KOG0156] Cytochrome P450 CYP2 subfamily; [GO:0055114] oxidation-reduction process; [GO:0016705] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; [GO:0020037] heme binding; [PTHR24298] FAMILY NOT NAMED; [PF00067] Cytochrome P450 104.40 0.6471 71 Mapoly0042s0088 [PF03801] HEC/Ndc80p family; [K11547] kinetochore protein NDC80; [PTHR10643] KINETOCHORE PROTEIN NDC80; [KOG0995] Centromere-associated protein HEC1 107.12 0.6905 72 Mapoly0024s0114 [GO:0055114] oxidation-reduction process; [PTHR31155] ACYL-(ACYL-CARRIER-PROTEIN) DESATURASE-RELATED; [GO:0006631] fatty acid metabolic process; [PF03405] Fatty acid desaturase; [GO:0045300] acyl-[acyl-carrier-protein] desaturase activity 108.50 0.5928 73 Mapoly0112s0022 [PTHR19932] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN; [GO:0005515] protein binding; [KOG1274] WD40 repeat protein; [K11274] chromosome transmission fidelity protein 4; [PTHR19932:SF10] WD REPEAT AND HMG-BOX DNA BINDING PROTEIN 1; [PF00400] WD domain, G-beta repeat; [PF12341] Protein of unknown function (DUF3639) 110.62 0.6942 74 Mapoly0020s0135 [PF03941] Inner centromere protein, ARK binding region; [PTHR13142:SF1] INCENP; [KOG1295] Nonsense-mediated decay protein Upf3; [PTHR13142] INNER CENTROMERE PROTEIN 110.91 0.6909 75 Mapoly0103s0079 [GO:0003677] DNA binding; [PTHR13763:SF0] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN; [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [GO:0005634] nucleus; [GO:0006281] DNA repair; [GO:0004842] ubiquitin-protein ligase activity; [KOG4362] Transcriptional regulator BRCA1; [PTHR13763] BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; [PF13771] PHD-like zinc-binding domain 111.39 0.6957 76 Mapoly0014s0182 - 111.86 0.6687 77 Mapoly0142s0005 [PF14874] Flagellar-associated PapD-like; [PTHR23053:SF0] SUBFAMILY NOT NAMED; [PTHR23053] DLEC1 (DELETED IN LUNG AND ESOPHAGEAL CANCER 1) 114.20 0.6186 78 Mapoly0155s0015 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 114.47 0.6283 79 Mapoly0098s0009 [K01104] protein-tyrosine phosphatase [EC:3.1.3.48]; [PF00581] Rhodanese-like domain; [PTHR10828:SF17] M-PHASE INDUCER PHOSPHATASE (DUAL SPECIFICITY PHOSPHATASE CDC25); [PTHR10828] M-PHASE INDUCER PHOSPHATASE (DUAL SPECIFICITY PHOSPHATASE CDC25); [3.1.3.48] Protein-tyrosine-phosphatase. 115.00 0.6812 80 Mapoly0013s0136 [PF13855] Leucine rich repeat; [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF00069] Protein kinase domain; [PF08263] Leucine rich repeat N-terminal domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PF12799] Leucine Rich repeats (2 copies); [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 115.08 0.6127 81 Mapoly0214s0011 [GO:0003677] DNA binding; [GO:0000786] nucleosome; [GO:0005634] nucleus; [KOG1744] Histone H2B; [PF00125] Core histone H2A/H2B/H3/H4; [K11252] histone H2B; [PTHR23428] HISTONE H2B 115.67 0.6781 82 Mapoly0043s0047 [GO:0005515] protein binding; [PF00612] IQ calmodulin-binding motif; [PTHR25069] FAMILY NOT NAMED; [PF00307] Calponin homology (CH) domain 115.84 0.6850 83 Mapoly0103s0008 - 115.93 0.6618 84 Mapoly0052s0121 [PTHR12197:SF13] SET AND MYND DOMAIN CONTAINING; [GO:0005515] protein binding; [PF13414] TPR repeat; [PF00856] SET domain; [PTHR12197] SET AND MYND DOMAIN CONTAINING; [PF00515] Tetratricopeptide repeat 116.20 0.6215 85 Mapoly0027s0041 [GO:0005643] nuclear pore; [PTHR13437] NUCLEOPORIN P58/P45 (NUCLEOPORIN-LIKE PROTEIN 1); [GO:0006913] nucleocytoplasmic transport 116.26 0.6779 86 Mapoly0016s0025 [PTHR21454:SF3] SUBFAMILY NOT NAMED; [PTHR21454] FAMILY NOT NAMED 116.49 0.5451 87 Mapoly0053s0106 - 117.35 0.6858 88 Mapoly0061s0132 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity; [KOG0246] Kinesin-like protein; [K10393] kinesin family member 2/24 118.41 0.6461 89 Mapoly0172s0017 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 120.09 0.6675 90 Mapoly0073s0027 [GO:0005524] ATP binding; [K07760] cyclin-dependent kinase [EC:2.7.11.22]; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [KOG0594] Protein kinase PCTAIRE and related kinases; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 120.95 0.6669 91 Mapoly0019s0176 [KOG0320] Predicted E3 ubiquitin ligase; [PF13920] Zinc finger, C3HC4 type (RING finger); [PTHR12183] UNCHARACTERIZED RING ZINC FINGER-CONTAINING PROTEIN 121.52 0.6500 92 Mapoly0003s0312 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 122.33 0.6124 93 Mapoly0039s0112 [PF03330] Rare lipoprotein A (RlpA)-like double-psi beta-barrel 122.83 0.6556 94 Mapoly0143s0029 - 123.80 0.6374 95 Mapoly0177s0008 [GO:0006260] DNA replication; [PF13191] AAA ATPase domain; [GO:0005634] nucleus; [KOG2543] Origin recognition complex, subunit 5; [PF14630] Origin recognition complex (ORC) subunit 5 C-terminus; [PTHR12705] ORIGIN RECOGNITION COMPLEX SUBUNIT 5; [GO:0000808] origin recognition complex; [K02607] origin recognition complex subunit 5 124.09 0.6809 96 Mapoly0189s0010 [PTHR15272:SF0] SUBFAMILY NOT NAMED; [PF12253] Chromatin assembly factor 1 subunit A; [PTHR15272] CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A (CAF-1 SUBUNIT A) 125.43 0.6655 97 Mapoly0119s0016 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [KOG0480] DNA replication licensing factor, MCM6 component; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630:SF43] DNA REPLICATION LICENSING FACTOR MCM6; [K02542] minichromosome maintenance protein 6; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain 125.46 0.6880 98 Mapoly0041s0116 [PTHR31246] FAMILY NOT NAMED; [PF07058] Myosin II heavy chain-like; [GO:0008017] microtubule binding; [GO:0007010] cytoskeleton organization 127.50 0.6401 99 Mapoly0007s0226 [GO:0003677] DNA binding; [KOG1756] Histone 2A; [PTHR23430] HISTONE H2A; [PF00125] Core histone H2A/H2B/H3/H4 127.51 0.6667 100 Mapoly0065s0078 [PTHR24115:SF171] SUBFAMILY NOT NAMED; [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [K10403] kinesin family member 22; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 128.64 0.6701 101 Mapoly0136s0022 [PF03357] Snf7; [KOG3230] Vacuolar assembly/sorting protein DID4; [PTHR10476] CHARGED MULTIVESICULAR BODY PROTEIN; [GO:0015031] protein transport 129.61 0.6193 102 Mapoly0070s0075 [GO:0055114] oxidation-reduction process; [GO:0006779] porphyrin-containing compound biosynthetic process; [PF01218] Coproporphyrinogen III oxidase; [PTHR10755] COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL; [GO:0004109] coproporphyrinogen oxidase activity; [KOG1518] Coproporphyrinogen III oxidase CPO/HEM13 130.04 0.6578 103 Mapoly0086s0039 [PTHR12145:SF11] SUBFAMILY NOT NAMED; [PF03190] Protein of unknown function, DUF255; [KOG2244] Highly conserved protein containing a thioredoxin domain; [PTHR12145] UNCHARACTERIZED 130.48 0.5544 104 Mapoly0005s0174 [GO:0005524] ATP binding; [KOG0933] Structural maintenance of chromosome protein 2 (chromosome condensation complex Condensin, subunit E); [GO:0007076] mitotic chromosome condensation; [GO:0005515] protein binding; [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0000796] condensin complex; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PTHR18937:SF9] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC2; [K06674] structural maintenance of chromosome 2; [PF06470] SMC proteins Flexible Hinge Domain 130.77 0.6825 105 Mapoly0013s0072 [PTHR16092] SEC3/SYNTAXIN-RELATED; [PF09763] Exocyst complex component Sec3; [KOG2148] Exocyst protein Sec3; [PF15277] Exocyst complex component SEC3 N-terminal PIP2 binding PH 130.81 0.6088 106 Mapoly0060s0056 [GO:0008168] methyltransferase activity; [PTHR10629] CYTOSINE-SPECIFIC METHYLTRANSFERASE; [PF01426] BAH domain; [GO:0003682] chromatin binding; [K00558] DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]; [PF00385] Chromo (CHRromatin Organisation MOdifier) domain; [PF00145] C-5 cytosine-specific DNA methylase; [2.1.1.37] DNA (cytosine-5-)-methyltransferase. 130.97 0.6752 107 Mapoly0172s0018 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 131.84 0.6564 108 Mapoly0125s0003 - 132.00 0.6579 109 Mapoly0027s0105 - 136.46 0.6552 110 Mapoly0004s0300 [GO:0005524] ATP binding; [PTHR11909:SF7] CELL DIVISION CONTROL PROTEIN 7; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [2.7.11.1] Non-specific serine/threonine protein kinase.; [K02214] cell division control protein 7 [EC:2.7.11.1]; [KOG1167] Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination; [GO:0006468] protein phosphorylation; [PTHR11909] CASEIN KINASE-RELATED 139.07 0.6777 111 Mapoly0024s0031 [PTHR11525:SF0] SUBFAMILY NOT NAMED; [PTHR11525] FARNESYL-PYROPHOSPHATE SYNTHETASE; [2.5.1.1] Dimethylallyltranstransferase.; [GO:0008299] isoprenoid biosynthetic process; [PF00348] Polyprenyl synthetase; [KOG0711] Polyprenyl synthetase; [2.5.1.10] (2E,6E)-farnesyl diphosphate synthase.; [K00787] farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] 139.93 0.6107 112 Mapoly0013s0172 [K09228] KRAB domain-containing zinc finger protein; [PTHR11389:SF394] KRAB-RELATED C2H2-TYPE ZINC-FINGER PROTEIN; [PTHR11389] ZINC FINGER PROTEIN; [PF13894] C2H2-type zinc finger 139.94 0.5999 113 Mapoly0001s0491 [PF00754] F5/8 type C domain; [KOG4276] Predicted hormone receptor interactor; [PTHR24413] FAMILY NOT NAMED; [PF00651] BTB/POZ domain; [PF07707] BTB And C-terminal Kelch; [GO:0005515] protein binding; [PF12248] Farnesoic acid 0-methyl transferase; [GO:0007155] cell adhesion 140.56 0.5718 114 Mapoly0064s0049 [PTHR19321:SF5] PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED; [GO:0000226] microtubule cytoskeleton organization; [GO:0000910] cytokinesis; [GO:0008017] microtubule binding; [PF03999] Microtubule associated protein (MAP65/ASE1 family); [KOG4302] Microtubule-associated protein essential for anaphase spindle elongation; [PTHR19321] PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED 141.07 0.6482 115 Mapoly0022s0115 [GO:0006284] base-excision repair; [PF03352] Methyladenine glycosylase; [GO:0008725] DNA-3-methyladenine glycosylase activity; [3.2.2.20] DNA-3-methyladenine glycosylase I.; [K01246] DNA-3-methyladenine glycosylase I [EC:3.2.2.20]; [PTHR31116] FAMILY NOT NAMED 142.23 0.6442 116 Mapoly0001s0188 - 144.04 0.6650 117 Mapoly0214s0010 [KOG3467] Histone H4; [GO:0003677] DNA binding; [PTHR10484] HISTONE H4; [K11254] histone H4; [PF00125] Core histone H2A/H2B/H3/H4 146.07 0.6587 118 Mapoly0004s0096 [K11548] kinetochore protein Nuf2; [GO:0007067] mitosis; [PTHR21650] MEMBRALIN/KINETOCHORE PROTEIN NUF2; [PF03800] Nuf2 family; [KOG4438] Centromere-associated protein NUF2; [GO:0000775] chromosome, centromeric region; [PTHR21650:SF2] KINETOCHORE PROTEIN NUF2 148.25 0.6658 119 Mapoly0037s0043 [PTHR24003] MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN-RELATED; [KOG4332] Predicted sugar transporter; [PF05631] Protein of unknown function (DUF791); [PTHR24003:SF368] SUBFAMILY NOT NAMED 149.90 0.5961 120 Mapoly0002s0222 [KOG1991] Nuclear transport receptor RANBP7/RANBP8 (importin beta superfamily); [PF03810] Importin-beta N-terminal domain; [GO:0006886] intracellular protein transport; [PTHR10997] IMPORTIN-7, 8, 11; [GO:0008536] Ran GTPase binding 150.82 0.5884 121 Mapoly0039s0109 [KOG0553] TPR repeat-containing protein; [PF14559] Tetratricopeptide repeat; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR 153.92 0.6459 122 Mapoly0109s0019 [KOG1375] Beta tubulin; [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [K07375] tubulin beta; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [GO:0005525] GTP binding 154.73 0.6402 123 Mapoly0081s0060 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24350] SERINE/THREONINE-PROTEIN KINASE IAL-RELATED; [2.7.11.1] Non-specific serine/threonine protein kinase.; [KOG0580] Serine/threonine protein kinase; [GO:0006468] protein phosphorylation; [K08850] aurora kinase, other [EC:2.7.11.1] 154.84 0.5901 124 Mapoly0102s0037 [GO:0003677] DNA binding; [KOG1745] Histones H3 and H4; [GO:0000786] nucleosome; [K11253] histone H3; [PTHR11426] HISTONE H3; [PF00125] Core histone H2A/H2B/H3/H4 154.92 0.6529 125 Mapoly0093s0001 [GO:0005506] iron ion binding; [KOG0156] Cytochrome P450 CYP2 subfamily; [GO:0055114] oxidation-reduction process; [GO:0016705] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; [K05280] flavonoid 3'-monooxygenase [EC:1.14.13.21]; [GO:0020037] heme binding; [1.14.13.21] Flavonoid 3'-monooxygenase.; [PTHR24298] FAMILY NOT NAMED; [PF00067] Cytochrome P450 155.88 0.5705 126 Mapoly0010s0152 [PTHR13561] DNA REPLICATION REGULATOR DPB11-RELATED; [PTHR13561:SF5] DNA REPLICATION REGULATOR DPB11; [PF00628] PHD-finger; [GO:0005515] protein binding; [PF00533] BRCA1 C Terminus (BRCT) domain; [PF12738] twin BRCT domain 157.89 0.6601 127 Mapoly0044s0021 [KOG0275] Conserved WD40 repeat-containing protein; [PTHR22848] WD40 REPEAT PROTEIN; [GO:0005515] protein binding; [K13111] WD40 repeat-containing protein SMU1; [PF00400] WD domain, G-beta repeat 159.01 0.6534 128 Mapoly0038s0109 [PTHR11842] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2; [GO:0007094] mitotic spindle assembly checkpoint; [PF02301] HORMA domain; [K02537] mitotic spindle assembly checkpoint protein MAD2; [PTHR11842:SF11] MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A; [KOG3285] Spindle assembly checkpoint protein 159.71 0.6443 129 Mapoly0067s0089 [GO:0005515] protein binding; [PF00498] FHA domain; [PTHR23308] NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 159.80 0.6540 130 Mapoly0035s0099 [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02321] DNA polymerase alpha subunit B; [PTHR23061:SF12] SUBFAMILY NOT NAMED; [KOG1625] DNA polymerase alpha-primase complex, polymerase-associated subunit B; [PF04042] DNA polymerase alpha/epsilon subunit B; [PTHR23061] DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; [GO:0003887] DNA-directed DNA polymerase activity; [PF08418] DNA polymerase alpha subunit B N-terminal 160.48 0.6625 131 Mapoly0007s0134 [KOG3000] Microtubule-binding protein involved in cell cycle control; [GO:0005515] protein binding; [PTHR10623:SF6] MICROTUBULE-ASSOCIATED PROTEIN EB1 (MICROTUBULE PLUS-END BINDING PROTEIN); [PF03271] EB1-like C-terminal motif; [GO:0008017] microtubule binding; [PTHR10623] MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER; [PF00307] Calponin homology (CH) domain 160.79 0.6503 132 Mapoly0002s0043 [GO:0003676] nucleic acid binding; [PF02037] SAP domain 162.48 0.6364 133 Mapoly0007s0227 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PF00493] MCM2/3/5 family; [K02212] minichromosome maintenance protein 4 (cell division control protein 54); [KOG0478] DNA replication licensing factor, MCM4 component; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 163.63 0.6657 134 Mapoly0101s0052 - 165.00 0.5677 135 Mapoly0008s0109 [PTHR18952] CARBONIC ANHYDRASE; [PF00194] Eukaryotic-type carbonic anhydrase; [KOG0382] Carbonic anhydrase 165.54 0.6264 136 Mapoly0030s0056 [PF00134] Cyclin, N-terminal domain; [PTHR10177] CYCLINE; [PF02984] Cyclin, C-terminal domain; [GO:0005634] nucleus; [KOG0656] G1/S-specific cyclin D 165.65 0.6468 137 Mapoly0025s0104 - 166.36 0.6416 138 Mapoly0043s0112 [PTHR21780] UNCHARACTERIZED; [KOG4670] Uncharacterized conserved membrane protein; [PTHR21780:SF0] SUBFAMILY NOT NAMED; [PF09786] Cytochrome B561, N terminal 168.46 0.6582 139 Mapoly0001s0105 [K02541] minichromosome maintenance protein 3; [KOG0479] DNA replication licensing factor, MCM3 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [PTHR11630:SF46] DNA REPLICATION LICENSING FACTOR MCM3; [PF00493] MCM2/3/5 family; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [PF14551] MCM N-terminal domain 169.09 0.6605 140 Mapoly0002s0035 - 169.73 0.6533 141 Mapoly0042s0023 [GO:0005524] ATP binding; [2.7.12.1] Dual-specificity kinase.; [KOG0198] MEKK and related serine/threonine protein kinases; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [K08866] serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]; [PTHR22974] MIXED LINEAGE PROTEIN KINASE 172.14 0.6597 142 Mapoly0004s0127 - 173.10 0.6286 143 Mapoly0022s0157 [PTHR22601] ISP4 LIKE PROTEIN; [GO:0055085] transmembrane transport; [KOG2262] Sexual differentiation process protein ISP4; [PF03169] OPT oligopeptide transporter protein 173.90 0.5881 144 Mapoly0012s0165 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 174.26 0.5968 145 Mapoly0030s0020 [KOG2545] Conserved membrane protein; [PTHR13489:SF0] SUBFAMILY NOT NAMED; [PF13615] Putative alanine racemase; [PF09739] Mini-chromosome maintenance replisome factor; [PTHR13489] UNCHARACTERIZED 176.18 0.6536 146 Mapoly0051s0023 [PF00488] MutS domain V; [GO:0005524] ATP binding; [KOG0217] Mismatch repair ATPase MSH6 (MutS family); [PTHR11361] DNA MISMATCH REPAIR MUTS RELATED PROTEINS; [PF05188] MutS domain II; [GO:0006298] mismatch repair; [GO:0030983] mismatched DNA binding; [PF01624] MutS domain I; [PF05192] MutS domain III 177.99 0.6660 147 Mapoly0060s0047 [GO:0003723] RNA binding; [PTHR10288] KH DOMAIN CONTAINING RNA BINDING PROTEIN; [PF00013] KH domain; [KOG2191] RNA-binding protein NOVA1/PASILLA and related KH domain proteins 178.77 0.6136 148 Mapoly0161s0024 - 179.53 0.5502 149 Mapoly0007s0041 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 179.55 0.6030 150 Mapoly0010s0058 [PF08879] WRC 181.20 0.5093 151 Mapoly0075s0022 [KOG0482] DNA replication licensing factor, MCM7 component; [GO:0003677] DNA binding; [GO:0005524] ATP binding; [GO:0006260] DNA replication; [K02210] minichromosome maintenance protein 7 (cell division control protein 47); [PF00493] MCM2/3/5 family; [GO:0042555] MCM complex; [GO:0005634] nucleus; [GO:0006270] DNA replication initiation; [PTHR11630] DNA REPLICATION LICENSING FACTOR; [GO:0003678] DNA helicase activity; [PF14551] MCM N-terminal domain; [PTHR11630:SF26] DNA REPLICATION LICENSING FACTOR MCM7 181.70 0.6555 152 Mapoly0108s0018 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 182.71 0.5956 153 Mapoly0007s0096 [4.2.2.2] Pectate lyase.; [K01728] pectate lyase [EC:4.2.2.2]; [PF00544] Pectate lyase; [PTHR31683] FAMILY NOT NAMED 184.92 0.6162 154 Mapoly0191s0002 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [K07374] tubulin alpha; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [KOG1376] Alpha tubulin; [GO:0005525] GTP binding 186.44 0.6470 155 Mapoly0030s0095 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [K10405] kinesin family member C1; [GO:0003777] microtubule motor activity 191.20 0.6317 156 Mapoly0048s0012 [GO:0015035] protein disulfide oxidoreductase activity; [KOG1752] Glutaredoxin and related proteins; [PTHR10168] GLUTAREDOXIN; [GO:0045454] cell redox homeostasis; [PF00462] Glutaredoxin; [GO:0009055] electron carrier activity 191.58 0.5424 157 Mapoly0095s0028 - 192.48 0.5799 158 Mapoly0121s0024 [PF13513] HEAT-like repeat; [PTHR31355] FAMILY NOT NAMED 192.73 0.5546 159 Mapoly0041s0151 [PTHR23151] DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED; [2.3.1.12] Dihydrolipoyllysine-residue acetyltransferase.; [PF00364] Biotin-requiring enzyme; [KOG0557] Dihydrolipoamide acetyltransferase; [GO:0016746] transferase activity, transferring acyl groups; [GO:0008152] metabolic process; [K00627] pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]; [PF00198] 2-oxoacid dehydrogenases acyltransferase (catalytic domain); [PF02817] e3 binding domain 192.83 0.6087 160 Mapoly0209s0008 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG0387] Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain); [PF00271] Helicase conserved C-terminal domain; [PTHR10799:SF67] DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE 193.19 0.6580 161 Mapoly0027s0005 [GO:0005515] protein binding; [KOG0290] Conserved WD40 repeat-containing protein AN11; [PTHR19919] WD REPEAT CONTAINING PROTEIN; [PF00400] WD domain, G-beta repeat 193.98 0.5240 162 Mapoly0091s0056 [PF05918] Apoptosis inhibitory protein 5 (API5); [KOG2213] Apoptosis inhibitor 5/fibroblast growth factor 2-interacting factor 2, and related proteins; [PTHR12758] APOPTOSIS INHIBITOR 5-RELATED 194.47 0.6429 163 Mapoly0025s0128 [PF00134] Cyclin, N-terminal domain; [PTHR10177] CYCLINE; [PF02984] Cyclin, C-terminal domain; [GO:0005634] nucleus; [PTHR10177:SF49] CYCLIN-A; [KOG0654] G2/Mitotic-specific cyclin A; [K06627] cyclin A 194.67 0.6285 164 Mapoly0085s0026 [PF00533] BRCA1 C Terminus (BRCT) domain; [PTHR23196] PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN 197.01 0.6405 165 Mapoly0084s0051 [2.1.1.43] Histone-lysine N-methyltransferase.; [GO:0005515] protein binding; [PF00856] SET domain; [KOG1079] Transcriptional repressor EZH1; [PTHR22884] SET DOMAIN PROTEINS; [K11430] enhancer of zeste [EC:2.1.1.43] 198.94 0.6156 166 Mapoly0047s0105 [KOG4308] LRR-containing protein; [PTHR10098] RAPSYN-RELATED; [PF13516] Leucine Rich repeat; [PF13414] TPR repeat 201.87 0.6404 167 Mapoly0010s0082 - 202.46 0.5813 168 Mapoly0160s0032 [PTHR11005] LYSOSOMAL ACID LIPASE-RELATED; [PF04083] Partial alpha/beta-hydrolase lipase region; [KOG2624] Triglyceride lipase-cholesterol esterase; [PF00561] alpha/beta hydrolase fold; [GO:0006629] lipid metabolic process 202.70 0.5481 169 Mapoly0065s0034 [GO:0000287] magnesium ion binding; [GO:0004743] pyruvate kinase activity; [GO:0006096] glycolysis; [GO:0030955] potassium ion binding; [PF02887] Pyruvate kinase, alpha/beta domain; [PF00224] Pyruvate kinase, barrel domain; [KOG2323] Pyruvate kinase; [PTHR11817] PYRUVATE KINASE 203.32 0.6226 170 Mapoly0081s0054 [PF13855] Leucine rich repeat; [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF13516] Leucine Rich repeat; [PF00069] Protein kinase domain; [PF08263] Leucine rich repeat N-terminal domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PF12799] Leucine Rich repeats (2 copies); [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 203.43 0.6031 171 Mapoly0011s0202 [GO:0003677] DNA binding; [GO:0005524] ATP binding; [PTHR10799] SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY-RELATED; [PF00176] SNF2 family N-terminal domain; [KOG1001] Helicase-like transcription factor HLTF/DNA helicase RAD5, DEAD-box superfamily; [PF00271] Helicase conserved C-terminal domain 205.22 0.6515 172 Mapoly0142s0034 [KOG4282] Transcription factor GT-2 and related proteins, contains trihelix DNA-binding/SANT domain; [PF13837] Myb/SANT-like DNA-binding domain 206.69 0.5016 173 Mapoly0037s0034 [K10744] ribonuclease H2 subunit B; [PTHR13383] FAMILY NOT NAMED; [PF09468] Ydr279p protein family (RNase H2 complex component); [GO:0005634] nucleus 208.10 0.6442 174 Mapoly0113s0034 [GO:0003677] DNA binding; [GO:0006355] regulation of transcription, DNA-dependent; [PF01698] Floricaula / Leafy protein 210.08 0.6292 175 Mapoly0140s0032 [PTHR12748] ORIGIN RECOGNITION COMPLEX SUBUNIT 3; [PTHR12748:SF0] SUBFAMILY NOT NAMED; [GO:0003677] DNA binding; [GO:0006260] DNA replication; [K02605] origin recognition complex subunit 3; [PF07034] Origin recognition complex (ORC) subunit 3 N-terminus; [KOG2538] Origin recognition complex, subunit 3; [GO:0005664] nuclear origin of replication recognition complex; [PF02178] AT hook motif 210.47 0.6467 176 Mapoly0072s0051 [PTHR22983] PROTEIN KINASE RELATED; [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [KOG0597] Serine-threonine protein kinase FUSED; [GO:0006468] protein phosphorylation 211.16 0.6385 177 Mapoly0111s0036 [K01303] acylaminoacyl-peptidase [EC:3.4.19.1]; [PTHR11731] PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; [KOG2100] Dipeptidyl aminopeptidase; [GO:0008236] serine-type peptidase activity; [GO:0006508] proteolysis; [PF00326] Prolyl oligopeptidase family; [3.4.19.1] Acylaminoacyl-peptidase. 211.74 0.5810 178 Mapoly0063s0076 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24056:SF0] CELL DIVISION PROTEIN KINASE 7; [K02202] cyclin-dependent kinase 7 [EC:2.7.11.22]; [KOG0659] Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 212.57 0.6203 179 Mapoly0029s0119 - 213.13 0.6001 180 Mapoly0009s0115 [PF03018] Dirigent-like protein; [PTHR21495] NUCLEOPORIN-RELATED 214.73 0.5605 181 Mapoly0060s0013 [6.3.4.14] Biotin carboxylase.; [GO:0005524] ATP binding; [GO:0016874] ligase activity; [PF02785] Biotin carboxylase C-terminal domain; [PF00289] Carbamoyl-phosphate synthase L chain, N-terminal domain; [6.4.1.2] Acetyl-CoA carboxylase.; [GO:0008152] metabolic process; [PTHR18866] CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE; [GO:0003824] catalytic activity; [K01961] acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]; [PF02786] Carbamoyl-phosphate synthase L chain, ATP binding domain 214.87 0.6179 182 Mapoly0130s0026 - 215.98 0.6052 183 Mapoly0001s0015 [PTHR13555] C2H2 ZINC FINGER CGI-62-RELATED 216.06 0.6077 184 Mapoly0030s0102 [PF08317] Spc7 kinetochore protein 216.12 0.6438 185 Mapoly0004s0250 [GO:0005643] nuclear pore; [PF07817] GLE1-like protein; [GO:0016973] poly(A)+ mRNA export from nucleus; [KOG2412] Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor; [PTHR12960:SF0] SUBFAMILY NOT NAMED; [PTHR12960] GLE-1-RELATED 216.44 0.6337 186 Mapoly0029s0041 [PF04515] Plasma-membrane choline transporter; [PTHR12385] CTL TRANSPORTER; [PTHR12385:SF4] CTL2-RELATED 216.77 0.5865 187 Mapoly0004s0273 [KOG1375] Beta tubulin; [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [K07375] tubulin beta; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [GO:0005525] GTP binding 216.89 0.5199 188 Mapoly0001s0010 [PTHR22926] PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE; [PF10555] Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1; [GO:0016021] integral to membrane; [PF00953] Glycosyl transferase family 4; [GO:0008963] phospho-N-acetylmuramoyl-pentapeptide-transferase activity 217.08 0.5789 189 Mapoly0078s0017 - 217.86 0.6331 190 Mapoly0045s0042 [KOG2475] CDC45 (cell division cycle 45)-like protein; [GO:0006270] DNA replication initiation; [PF02724] CDC45-like protein; [PTHR10507:SF0] CDC45-RELATED PROTEIN; [PTHR10507] CDC45-RELATED PROTEIN; [K06628] cell division control protein 45 217.92 0.6398 191 Mapoly0144s0003 - 218.21 0.6057 192 Mapoly0189s0011 [GO:0005524] ATP binding; [GO:0005515] protein binding; [K06675] structural maintenance of chromosome 4; [KOG0996] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C); [PTHR18937] STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; [PF02463] RecF/RecN/SMC N terminal domain; [GO:0051276] chromosome organization; [GO:0005694] chromosome; [PF06470] SMC proteins Flexible Hinge Domain 219.94 0.6343 193 Mapoly0019s0119 - 220.82 0.6390 194 Mapoly0058s0074 [GO:0009058] biosynthetic process; [PF00534] Glycosyl transferases group 1; [PTHR12526] GLYCOSYLTRANSFERASE 223.28 0.5817 195 Mapoly0031s0083 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [K02087] cyclin-dependent kinase 1 [EC:2.7.11.22]; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [KOG0594] Protein kinase PCTAIRE and related kinases; [2.7.11.22] Cyclin-dependent kinase.; [PTHR24056] CELL DIVISION PROTEIN KINASE 224.49 0.5048 196 Mapoly0055s0064 - 225.14 0.6329 197 Mapoly0211s0016 [PTHR21666] PEPTIDASE-RELATED; [PF01551] Peptidase family M23 225.86 0.5136 198 Mapoly0098s0043 [PF12717] non-SMC mitotic condensation complex subunit 1; [GO:0007076] mitotic chromosome condensation; [K11491] condensin-2 complex subunit D3; [PTHR14222:SF1] CONDENSIN; [PTHR14222] CONDENSIN 226.58 0.6357 199 Mapoly0050s0027 [PTHR10994:SF3] UNCHARACTERIZED; [PTHR10994] RETICULON; [PF03407] Nucleotide-diphospho-sugar transferase 227.58 0.4952 200 Mapoly0043s0030 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 230.78 0.5912