Guide Gene

Gene ID
Mapoly0079s0011
Organism
Marchantia polymorpha
Platform ID
Mpo
Description
-

Coexpressed Gene List


Marchantia polymorpha
Rank Gene ID Description MR PCC
Guide Mapoly0079s0011 - 0.00 1.0000
1 Mapoly0036s0027 [PF03134] TB2/DP1, HVA22 family; [PTHR12300:SF20] HVA22-LIKE PROTEIN; [KOG1726] HVA22/DP1 gene product-related proteins; [PTHR12300] HVA22-LIKE PROTEINS 7.21 0.6815
2 Mapoly0182s0009 [GO:0005524] ATP binding; [KOG0055] Multidrug/pheromone exporter, ABC superfamily; [GO:0016021] integral to membrane; [PF00664] ABC transporter transmembrane region; [GO:0016887] ATPase activity; [GO:0006810] transport; [GO:0055085] transmembrane transport; [GO:0042626] ATPase activity, coupled to transmembrane movement of substances; [PTHR24221] FAMILY NOT NAMED; [PF00005] ABC transporter 7.75 0.7197
3 Mapoly0060s0111 [GO:0016020] membrane; [PF06280] Fn3-like domain (DUF1034); [GO:0004252] serine-type endopeptidase activity; [PF00082] Subtilase family; [PF05922] Peptidase inhibitor I9; [GO:0005618] cell wall; [GO:0006508] proteolysis; [PTHR10795] PROPROTEIN CONVERTASE SUBTILISIN/KEXIN 9.27 0.6986
4 Mapoly0086s0072 [PTHR11005] LYSOSOMAL ACID LIPASE-RELATED; [PTHR11005:SF19] TRIACYLGLYCEROL LIPASE; [KOG2624] Triglyceride lipase-cholesterol esterase; [PF12697] Alpha/beta hydrolase family 11.36 0.6941
5 Mapoly0079s0009 - 14.83 0.6803
6 Mapoly0030s0082 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 17.75 0.6178
7 Mapoly0095s0015 [GO:0045454] cell redox homeostasis; [PF00085] Thioredoxin; [KOG0907] Thioredoxin; [PTHR18929] PROTEIN DISULFIDE ISOMERASE 18.49 0.5905
8 Mapoly0046s0119 [PF01545] Cation efflux family; [KOG1484] Putative Zn2+ transporter MSC2 (cation diffusion facilitator superfamily); [GO:0016021] integral to membrane; [GO:0055085] transmembrane transport; [K03295] cation efflux system protein, CDF family; [GO:0006812] cation transport; [GO:0008324] cation transmembrane transporter activity; [PTHR11562] CATION EFFLUX PROTEIN/ ZINC TRANSPORTER 18.89 0.6412
9 Mapoly0108s0047 - 19.80 0.6223
10 Mapoly0101s0066 [GO:0005515] protein binding; [PF00400] WD domain, G-beta repeat 20.20 0.6183
11 Mapoly0013s0138 [PF06749] Protein of unknown function (DUF1218); [PTHR31769] FAMILY NOT NAMED 22.58 0.6776
12 Mapoly0090s0065 [PF08123] Histone methylation protein DOT1; [GO:0018024] histone-lysine N-methyltransferase activity 23.32 0.6646
13 Mapoly0008s0187 [PTHR31183] FAMILY NOT NAMED 24.90 0.6498
14 Mapoly0053s0024 [GO:0006777] Mo-molybdopterin cofactor biosynthetic process; [PTHR22960] MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A; [PF01967] MoaC family; [K03639] molybdenum cofactor biosynthesis protein 25.81 0.5770
15 MapolyY_B0041 - 26.32 0.6707
16 Mapoly0004s0193 [PF13855] Leucine rich repeat; [GO:0005515] protein binding; [PTHR10588] FAMILY NOT NAMED; [PF14580] Leucine-rich repeat; [PF12799] Leucine Rich repeats (2 copies); [KOG0472] Leucine-rich repeat protein 30.00 0.6562
17 Mapoly0001s0198 [GO:0005524] ATP binding; [2.7.12.1] Dual-specificity kinase.; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [K08825] dual-specificity tyrosine-(Y)-phosphorylation regulated kinase [EC:2.7.12.1]; [PTHR24058] DUAL SPECIFICITY PROTEIN KINASE; [KOG0667] Dual-specificity tyrosine-phosphorylation regulated kinase; [GO:0006468] protein phosphorylation; [PTHR24058:SF22] DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 2 31.08 0.6442
18 Mapoly0068s0004 [GO:0004114] 3',5'-cyclic-nucleotide phosphodiesterase activity; [GO:0035556] intracellular signal transduction; [PF00233] 3'5'-cyclic nucleotide phosphodiesterase; [GO:0007165] signal transduction; [GO:0009190] cyclic nucleotide biosynthetic process; [GO:0016849] phosphorus-oxygen lyase activity; [PTHR11347] CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; [PF00211] Adenylate and Guanylate cyclase catalytic domain 37.12 0.6245
19 Mapoly0036s0089 - 40.42 0.6390
20 Mapoly0005s0172 [PTHR24322] FAMILY NOT NAMED; [K04708] 3-dehydrosphinganine reductase [EC:1.1.1.102]; [KOG1210] Predicted 3-ketosphinganine reductase; [1.1.1.102] 3-dehydrosphinganine reductase.; [GO:0016491] oxidoreductase activity; [GO:0008152] metabolic process; [PF00106] short chain dehydrogenase 41.57 0.6016
21 Mapoly0002s0277 [PTHR22936:SF15] gb def: Drosophila melanogaster CG15040 gene product; [GO:0016021] integral to membrane; [GO:0004252] serine-type endopeptidase activity; [PF01694] Rhomboid family; [KOG2289] Rhomboid family proteins; [PTHR22936] RHOMBOID-RELATED; [GO:0006508] proteolysis 42.99 0.6453
22 Mapoly0169s0015 [GO:0006355] regulation of transcription, DNA-dependent; [KOG3149] Transcription initiation factor IIF, auxiliary subunit; [PTHR23195] YEATS DOMAIN; [PF03366] YEATS family; [GO:0005634] nucleus; [K11341] YEATS domain-containing protein 4 49.72 0.6448
23 Mapoly0038s0070 [PTHR11527] SMALL HEAT-SHOCK PROTEIN (HSP20) FAMILY; [PF00011] Hsp20/alpha crystallin family 50.35 0.6444
24 Mapoly0013s0042 - 52.65 0.6410
25 Mapoly0060s0091 [GO:0016020] membrane; [PTHR11119] XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; [GO:0006810] transport; [GO:0055085] transmembrane transport; [KOG1292] Xanthine/uracil transporters; [GO:0005215] transporter activity; [PF00860] Permease family 53.03 0.5758
26 Mapoly0062s0064 [KOG4001] Axonemal dynein light chain; [PF10211] Axonemal dynein light chain; [K10410] dynein light intermediate chain, axonemal; [PTHR13183] AXONEMAL INNER ARM DYNEIN LIGHT CHAIN 28 54.90 0.6307
27 Mapoly0178s0022 [PF00072] Response regulator receiver domain; [GO:0035556] intracellular signal transduction; [PTHR16305] TESTICULAR SOLUBLE ADENYLYL CYCLASE; [GO:0000160] phosphorelay signal transduction system; [GO:0009190] cyclic nucleotide biosynthetic process; [GO:0016849] phosphorus-oxygen lyase activity; [PF00211] Adenylate and Guanylate cyclase catalytic domain 57.79 0.6380
28 Mapoly0004s0088 - 58.99 0.6221
29 Mapoly0059s0095 - 60.00 0.6423
30 Mapoly0094s0075 [KOG2819] Uncharacterized conserved protein; [PF03676] Uncharacterised protein family (UPF0183); [PTHR13465] UPF0183 PROTEIN 60.75 0.6441
31 Mapoly0060s0094 - 63.25 0.5255
32 Mapoly0058s0111 [PF02823] ATP synthase, Delta/Epsilon chain, beta-sandwich domain; [3.6.3.14] H(+)-transporting two-sector ATPase.; [GO:0046933] proton-transporting ATP synthase activity, rotational mechanism; [GO:0046961] proton-transporting ATPase activity, rotational mechanism; [GO:0045261] proton-transporting ATP synthase complex, catalytic core F(1); [KOG1758] Mitochondrial F1F0-ATP synthase, subunit delta/ATP16; [K02134] F-type H+-transporting ATPase subunit delta [EC:3.6.3.14]; [GO:0015986] ATP synthesis coupled proton transport; [PTHR13822] ATP SYNTHASE DELTA/EPSILON CHAIN 65.51 0.6167
33 Mapoly0028s0089 [KOG1375] Beta tubulin; [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [K07375] tubulin beta; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [GO:0005525] GTP binding 66.80 0.6272
34 Mapoly0072s0068 [K13993] HSP20 family protein; [KOG0710] Molecular chaperone (small heat-shock protein Hsp26/Hsp42); [PTHR11527] SMALL HEAT-SHOCK PROTEIN (HSP20) FAMILY; [PF00011] Hsp20/alpha crystallin family 67.73 0.6210
35 Mapoly0004s0273 [KOG1375] Beta tubulin; [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [K07375] tubulin beta; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [GO:0005525] GTP binding 70.42 0.5690
36 Mapoly0020s0116 [K06234] Ras-related protein Rab-23; [GO:0007264] small GTPase mediated signal transduction; [PTHR24073] FAMILY NOT NAMED; [PF00071] Ras family; [KOG4252] GTP-binding protein; [PTHR24073:SF209] SUBFAMILY NOT NAMED; [GO:0005525] GTP binding 70.89 0.6246
37 Mapoly0032s0065 [GO:0006486] protein glycosylation; [GO:0008373] sialyltransferase activity; [PTHR13713] SIALYLTRANSFERASE; [PF00777] Glycosyltransferase family 29 (sialyltransferase) 71.44 0.6366
38 Mapoly0198s0008 [GO:0006355] regulation of transcription, DNA-dependent; [GO:0005667] transcription factor complex; [GO:0003700] sequence-specific DNA binding transcription factor activity; [PF02319] E2F/DP family winged-helix DNA-binding domain; [PTHR12081:SF7] TRANSCRIPTION FACTOR E2F; [PTHR12081] TRANSCRIPTION FACTOR E2F 72.00 0.6253
39 Mapoly0013s0198 - 78.14 0.5782
40 Mapoly0090s0019 - 78.97 0.6234
41 Mapoly0079s0012 - 80.01 0.4732
42 Mapoly0192s0008 [PTHR12742] RNA-BINDING PROTEIN; [KOG1457] RNA binding protein (contains RRM repeats); [GO:0003676] nucleic acid binding; [PTHR12742:SF0] SUBFAMILY NOT NAMED; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 80.05 0.5780
43 Mapoly0007s0270 [PTHR11732] ALDO/KETO REDUCTASE; [PF00248] Aldo/keto reductase family 80.99 0.6149
44 Mapoly0143s0006 [PF06521] PAR1 protein 83.96 0.5980
45 Mapoly0170s0031 - 84.48 0.5883
46 Mapoly0019s0127 [PF15007] Centrosomal spindle body, CEP44; [PTHR31477] FAMILY NOT NAMED 85.98 0.5953
47 Mapoly0175s0018 - 88.77 0.5480
48 Mapoly0021s0154 - 90.28 0.6204
49 Mapoly0102s0022 [PF01988] VIT family; [PTHR31812] FAMILY NOT NAMED; [KOG4473] Uncharacterized membrane protein 95.34 0.6221
50 Mapoly0158s0009 [GO:0005524] ATP binding; [KOG0661] MAPK related serine/threonine protein kinase; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24055] MITOGEN-ACTIVATED PROTEIN KINASE; [GO:0006468] protein phosphorylation; [PTHR24055:SF72] MAPK/MAK/MRK OVERLAPPING KINASE-RELATED; [K08830] renal tumor antigen [EC:2.7.11.22]; [2.7.11.22] Cyclin-dependent kinase. 95.81 0.6175
51 Mapoly0020s0002 [GO:0000166] nucleotide binding; [PF00702] haloacid dehalogenase-like hydrolase; [KOG0204] Calcium transporting ATPase; [PTHR24093] FAMILY NOT NAMED; [PF00690] Cation transporter/ATPase, N-terminus; [PF00689] Cation transporting ATPase, C-terminus; [GO:0046872] metal ion binding; [PF00122] E1-E2 ATPase 96.00 0.6209
52 Mapoly0195s0002 [PF03357] Snf7; [KOG3229] Vacuolar sorting protein VPS24; [PTHR10476] CHARGED MULTIVESICULAR BODY PROTEIN; [K12193] charged multivesicular body protein 3; [PTHR10476:SF1] CHARGED MULTIVESICULAR BODY PROTEIN 3; [GO:0015031] protein transport 97.21 0.5419
53 Mapoly0072s0095 [PTHR12419:SF6] SUBFAMILY NOT NAMED; [PTHR12419] OTU DOMAIN CONTAINING PROTEIN; [PF02338] OTU-like cysteine protease 97.77 0.5745
54 Mapoly0060s0102 [PTHR12327:SF0] SUBFAMILY NOT NAMED; [PTHR12327] UNCHARACTERIZED; [GO:0071929] alpha-tubulin acetylation; [GO:0019799] tubulin N-acetyltransferase activity; [KOG4601] Uncharacterized conserved protein; [PF05301] Touch receptor neuron protein Mec-17 100.31 0.5694
55 Mapoly0079s0037 [PTHR21467] HEAT-LIKE REPEAT-CONTAINING PROTEIN; [KOG0211] Protein phosphatase 2A regulatory subunit A and related proteins 100.43 0.6104
56 Mapoly0009s0033 [KOG2652] RNA polymerase II transcription initiation factor TFIIA, large chain; [PF13920] Zinc finger, C3HC4 type (RING finger) 103.12 0.6008
57 Mapoly0011s0117 [PF13839] GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p 105.28 0.5250
58 Mapoly0039s0088 [KOG0978] E3 ubiquitin ligase involved in syntaxin degradation 105.80 0.6150
59 Mapoly0022s0048 [KOG2632] Rhomboid family proteins; [PTHR22790] RHOMBOID-RELATED; [GO:0005515] protein binding; [GO:0016021] integral to membrane; [GO:0004252] serine-type endopeptidase activity; [PF01694] Rhomboid family; [PF00627] UBA/TS-N domain 108.81 0.5323
60 Mapoly0064s0024 [PTHR15654] UNCHARACTERIZED; [PTHR15654:SF1] SUBFAMILY NOT NAMED; [PF13870] Domain of unknown function (DUF4201) 108.89 0.6153
61 Mapoly0037s0146 [PF13837] Myb/SANT-like DNA-binding domain 113.42 0.5831
62 Mapoly0033s0152 [GO:0005515] protein binding; [PTHR12442] DYNEIN INTERMEDIATE CHAIN; [PF00400] WD domain, G-beta repeat 114.32 0.5966
63 Mapoly0109s0062 [PF05018] Protein of unknown function (DUF667); [PTHR12458] ORF PROTEIN; [KOG3213] Transcription factor IIB 114.59 0.5398
64 Mapoly0001s0037 [PTHR12864] RAN BINDING PROTEIN 9-RELATED; [KOG2659] LisH motif-containing protein; [PF10607] CTLH/CRA C-terminal to LisH motif domain 114.65 0.5872
65 Mapoly0179s0021 [PTHR24089] FAMILY NOT NAMED; [PF00153] Mitochondrial carrier protein; [KOG0749] Mitochondrial ADP/ATP carrier proteins; [K05863] solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator) 117.30 0.6083
66 Mapoly0065s0056 - 117.61 0.4879
67 Mapoly0103s0016 [K10840] centrin-2; [KOG0028] Ca2+-binding protein (centrin/caltractin), EF-Hand superfamily protein; [PTHR23050] CALCIUM BINDING PROTEIN; [PF13499] EF-hand domain pair; [PF13833] EF-hand domain pair; [GO:0005509] calcium ion binding 118.25 0.6050
68 Mapoly0029s0103 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [KOG0616] cAMP-dependent protein kinase catalytic subunit (PKA); [PTHR24353] CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE; [GO:0006468] protein phosphorylation; [PF00027] Cyclic nucleotide-binding domain 118.35 0.6040
69 Mapoly0120s0003 [PF00091] Tubulin/FtsZ family, GTPase domain; [GO:0005874] microtubule; [PTHR11588] TUBULIN; [GO:0007017] microtubule-based process; [PF03953] Tubulin C-terminal domain; [GO:0006184] GTP catabolic process; [K07374] tubulin alpha; [GO:0003924] GTPase activity; [GO:0051258] protein polymerization; [GO:0043234] protein complex; [KOG1376] Alpha tubulin; [GO:0005525] GTP binding 125.22 0.5478
70 Mapoly0067s0066 [PF14825] Domain of unknown function (DUF4483) 125.32 0.6063
71 Mapoly0052s0127 [PF13855] Leucine rich repeat; [PF13516] Leucine Rich repeat; [PF08263] Leucine rich repeat N-terminal domain; [GO:0005515] protein binding; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE; [KOG0472] Leucine-rich repeat protein 126.89 0.5596
72 Mapoly0008s0205 [PF07719] Tetratricopeptide repeat; [PF13414] TPR repeat; [PTHR20931] UNCHARACTERIZED; [KOG4340] Uncharacterized conserved protein 127.15 0.5897
73 Mapoly0119s0039 [KOG0541] Alkyl hydroperoxide reductase/peroxiredoxin; [PTHR10430:SF8] PEROXIREDOXIN; [GO:0016491] oxidoreductase activity; [PF08534] Redoxin; [PTHR10430] PEROXIREDOXIN 130.60 0.5984
74 Mapoly0001s0460 - 131.06 0.6097
75 Mapoly0004s0231 - 131.54 0.5722
76 Mapoly0033s0049 [PF05018] Protein of unknown function (DUF667); [PTHR12458:SF7] SUBFAMILY NOT NAMED; [PTHR12458] ORF PROTEIN 132.17 0.6069
77 Mapoly0955s0001 [PF14368] Probable lipid transfer 133.94 0.5883
78 Mapoly0011s0024 - 135.62 0.4135
79 Mapoly0009s0085 [PTHR23284] PROLACTIN REGULATORY ELEMENT BINDING PROTEIN; [GO:0005515] protein binding; [PTHR23284:SF1] gb def: Hypothetical protein F4F15.300; [KOG0771] Prolactin regulatory element-binding protein/Protein transport protein SEC12p; [PF00400] WD domain, G-beta repeat 139.53 0.4659
80 Mapoly0125s0010 [PTHR23213] FORMIN-RELATED 140.19 0.5820
81 Mapoly0048s0108 - 140.58 0.5439
82 Mapoly0009s0194 [PTHR12764:SF4] WD REPEAT DOMAIN-RELATED; [PTHR12764] WD REPEAT DOMAIN-RELATED 141.17 0.5777
83 Mapoly0182s0010 [GO:0005515] protein binding; [K03030] 26S proteasome regulatory subunit N11; [PF13012] Maintenance of mitochondrial structure and function; [PF01398] JAB1/Mov34/MPN/PAD-1 ubiquitin protease; [KOG1555] 26S proteasome regulatory complex, subunit RPN11; [PTHR10410] EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED; [PTHR10410:SF5] 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 14 141.21 0.5416
84 Mapoly0066s0043 [PTHR21083:SF0] SUBFAMILY NOT NAMED; [PF08190] pre-RNA processing PIH1/Nop17; [PTHR21083] TWISTER 144.33 0.5705
85 Mapoly0064s0051 - 144.43 0.6004
86 Mapoly0077s0010 [GO:0005515] protein binding; [PTHR13720] WD-40 REPEAT PROTEIN; [KOG0279] G protein beta subunit-like protein; [PF00400] WD domain, G-beta repeat 146.64 0.5850
87 Mapoly0031s0173 [GO:0005507] copper ion binding; [GO:0009055] electron carrier activity; [PF02298] Plastocyanin-like domain 147.12 0.5848
88 Mapoly0056s0027 [KOG0710] Molecular chaperone (small heat-shock protein Hsp26/Hsp42); [PTHR11527] SMALL HEAT-SHOCK PROTEIN (HSP20) FAMILY; [PF00011] Hsp20/alpha crystallin family 148.49 0.5869
89 Mapoly0043s0017 [PF03083] Sugar efflux transporter for intercellular exchange; [KOG1623] Multitransmembrane protein; [PTHR10791] RAG1-ACTIVATING PROTEIN 1 148.92 0.5688
90 Mapoly0094s0058 [PTHR12999] FAMILY NOT NAMED; [GO:0008270] zinc ion binding; [PF00641] Zn-finger in Ran binding protein and others 149.01 0.5678
91 Mapoly0037s0099 [PF13837] Myb/SANT-like DNA-binding domain 150.00 0.6008
92 Mapoly0067s0023 [PTHR14594:SF1] P10-BINDING PROTEIN BITE; [PF11559] Afadin- and alpha -actinin-Binding; [PTHR14594] CENTROSOMAL PROTEIN OF 70 KDA 150.98 0.5902
93 Mapoly0019s0184 [PTHR31867] FAMILY NOT NAMED; [PF03330] Rare lipoprotein A (RlpA)-like double-psi beta-barrel; [PF01357] Pollen allergen 151.69 0.5754
94 Mapoly0016s0029 - 153.36 0.5606
95 Mapoly0081s0036 [PF02469] Fasciclin domain 153.62 0.5801
96 Mapoly0114s0031 - 153.70 0.5758
97 Mapoly0114s0002 [PF03168] Late embryogenesis abundant protein; [PTHR31852] FAMILY NOT NAMED 154.50 0.5965
98 Mapoly0006s0030 [GO:0005507] copper ion binding; [GO:0009055] electron carrier activity; [PF02298] Plastocyanin-like domain 155.18 0.5799
99 Mapoly0005s0287 [GO:0003723] RNA binding; [PF14608] Zinc finger C-x8-C-x5-C-x3-H type; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PTHR10288:SF5] ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN; [PTHR10288] KH DOMAIN CONTAINING RNA BINDING PROTEIN; [PF00013] KH domain; [GO:0046872] metal ion binding 155.62 0.5734
100 Mapoly0002s0310 [GO:0005515] protein binding; [PTHR22844] F-BOX AND WD40 DOMAIN PROTEIN; [KOG0313] Microtubule binding protein YTM1 (contains WD40 repeats); [PF00400] WD domain, G-beta repeat 157.80 0.5722
101 Mapoly0010s0182 [GO:0005524] ATP binding; [KOG2355] Predicted ABC-type transport, ATPase component/CCR4 associated factor; [PTHR24220] FAMILY NOT NAMED; [GO:0016887] ATPase activity; [PTHR24220:SF76] PUTATIVE UNCHARACTERIZED PROTEIN PY00170 (FRAGMENT); [PF00005] ABC transporter 158.06 0.4510
102 Mapoly0092s0040 [GO:0005515] protein binding; [PF00498] FHA domain; [PTHR23308] NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1; [KOG1880] Nuclear inhibitor of phosphatase-1 160.11 0.4979
103 Mapoly0002s0222 [KOG1991] Nuclear transport receptor RANBP7/RANBP8 (importin beta superfamily); [PF03810] Importin-beta N-terminal domain; [GO:0006886] intracellular protein transport; [PTHR10997] IMPORTIN-7, 8, 11; [GO:0008536] Ran GTPase binding 164.70 0.5428
104 Mapoly0037s0142 - 167.57 0.5574
105 Mapoly0103s0068 [KOG2250] Glutamate/leucine/phenylalanine/valine dehydrogenases; [1.4.1.3] Glutamate dehydrogenase (NAD(P)(+)).; [GO:0055114] oxidation-reduction process; [PTHR11606] GLUTAMATE DEHYDROGENASE; [PTHR11606:SF2] GLUTAMATE DEHYDROGENASE; [K00261] glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]; [GO:0016491] oxidoreductase activity; [PF00208] Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; [GO:0006520] cellular amino acid metabolic process; [PF02812] Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 168.41 0.5477
106 Mapoly0128s0008 [GO:0016787] hydrolase activity; [PTHR31835] FAMILY NOT NAMED; [PF00293] NUDIX domain 168.57 0.4398
107 Mapoly0094s0035 [KOG3077] Uncharacterized conserved protein; [PF03556] Cullin binding; [PTHR12281] RP42 RELATED 169.66 0.4042
108 Mapoly0163s0019 [PTHR12677] UNCHARACTERIZED; [PF09335] SNARE associated Golgi protein 170.02 0.5115
109 Mapoly0068s0006 - 170.75 0.5448
110 Mapoly0045s0058 - 171.46 0.4893
111 Mapoly0070s0037 [PTHR10044] INHIBITOR OF APOPTOSIS; [PF00097] Zinc finger, C3HC4 type (RING finger); [GO:0016881] acid-amino acid ligase activity; [6.3.2.19] Ubiquitin--protein ligase.; [K10586] baculoviral IAP repeat-containing protein 6 (apollon) [EC:6.3.2.19]; [KOG0417] Ubiquitin-protein ligase; [GO:0046872] metal ion binding; [PF00179] Ubiquitin-conjugating enzyme 175.74 0.5025
112 Mapoly0043s0021 [KOG0919] C-5 cytosine-specific DNA methylase; [GO:0008168] methyltransferase activity; [PF11926] Domain of unknown function (DUF3444); [PTHR23068:SF2] gb def: Hypothetical protein F8M21_260; [PTHR23068] DNA (CYTOSINE-5-)-METHYLTRANSFERASE 3-RELATED; [PF00145] C-5 cytosine-specific DNA methylase 175.90 0.5702
113 Mapoly0046s0068 [GO:0005515] protein binding; [PF13639] Ring finger domain; [GO:0008270] zinc ion binding 178.42 0.5670
114 Mapoly0007s0229 [KOG0131] Splicing factor 3b, subunit 4; [PTHR23139] RNA-BINDING PROTEIN; [PF14259] RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); [GO:0003676] nucleic acid binding; [PTHR23139:SF9] SPLICING FACTOR U2AF LARGE SUBUNIT; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 183.47 0.5836
115 Mapoly0037s0015 - 184.45 0.5552
116 Mapoly0212s0006 [PTHR15504] NASOPHARYNGEAL EPITHELIUM SPECIFIC PROTEIN 1; [PF13868] Tumour suppressor, Mitostatin 185.60 0.5392
117 Mapoly0031s0045 [GO:0016020] membrane; [GO:0005524] ATP binding; [PF08370] Plant PDR ABC transporter associated; [GO:0016887] ATPase activity; [PTHR19241] ATP-BINDING CASSETTE TRANSPORTER; [PF01061] ABC-2 type transporter; [PF14510] ABC-transporter extracellular N-terminal; [KOG0065] Pleiotropic drug resistance proteins (PDR1-15), ABC superfamily; [PF00005] ABC transporter 186.25 0.5655
118 Mapoly0001s0120 [PF00225] Kinesin motor domain; [GO:0007018] microtubule-based movement; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0008017] microtubule binding; [KOG0242] Kinesin-like protein; [GO:0003777] microtubule motor activity; [PTHR24115:SF70] SUBFAMILY NOT NAMED; [GO:0005871] kinesin complex 190.64 0.5757
119 Mapoly0003s0010 [PF13864] Calmodulin-binding; [PTHR21490:SF0] SUBFAMILY NOT NAMED; [PTHR21490] UNCHARACTERIZED 192.48 0.5473
120 Mapoly0058s0073 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 192.80 0.5452
121 Mapoly0059s0046 - 193.03 0.5678
122 Mapoly0134s0033 [KOG0739] AAA+-type ATPase; [GO:0005524] ATP binding; [PTHR14690] UNCHARACTERIZED; [PF00004] ATPase family associated with various cellular activities (AAA); [PTHR14690:SF0] SUBFAMILY NOT NAMED 193.39 0.5485
123 Mapoly0159s0025 [GO:0016020] membrane; [PTHR10027] CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; [PTHR10027:SF10] CATION CHANNEL FAMILY PROTEIN-RELATED; [PF00520] Ion transport protein; [GO:0006813] potassium ion transport; [GO:0055085] transmembrane transport; [GO:0015269] calcium-activated potassium channel activity; [PF03493] Calcium-activated BK potassium channel alpha subunit; [GO:0006811] ion transport; [GO:0005216] ion channel activity 195.58 0.5586
124 Mapoly0014s0204 [PTHR24012] FAMILY NOT NAMED; [PTHR24012:SF31] SUBFAMILY NOT NAMED; [GO:0003676] nucleic acid binding; [PF00076] RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); [KOG0148] Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily) 196.57 0.5736
125 Mapoly0001s0219 [2.5.1.46] Deoxyhypusine synthase.; [PTHR11703] DEOXYHYPUSINE SYNTHASE; [K00809] deoxyhypusine synthase [EC:2.5.1.46]; [GO:0008612] peptidyl-lysine modification to hypusine; [PF01916] Deoxyhypusine synthase; [KOG2924] Deoxyhypusine synthase 197.58 0.5214
126 Mapoly0114s0003 [PTHR13379] UNCHARACTERIZED DUF1308; [PF07000] Protein of unknown function (DUF1308); [KOG4529] Uncharacterized conserved protein 197.77 0.4880
127 Mapoly0094s0037 - 198.74 0.5191
128 Mapoly0004s0232 [GO:0003677] DNA binding; [PF00538] linker histone H1 and H5 family; [GO:0000786] nucleosome; [GO:0005634] nucleus; [GO:0006334] nucleosome assembly 199.48 0.5090
129 Mapoly0191s0007 [2.1.1.77] Protein-L-isoaspartate(D-aspartate) O-methyltransferase.; [GO:0004719] protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; [KOG1661] Protein-L-isoaspartate(D-aspartate) O-methyltransferase; [PF01135] Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); [K00573] protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]; [PTHR11579] PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; [GO:0006464] cellular protein modification process 200.48 0.5293
130 Mapoly0115s0002 - 201.51 0.5622
131 Mapoly0065s0082 - 201.77 0.5372
132 Mapoly0137s0011 [PF07227] Protein of unknown function (DUF1423) 205.16 0.5156
133 Mapoly0065s0004 - 205.67 0.5654
134 Mapoly0020s0059 [KOG0028] Ca2+-binding protein (centrin/caltractin), EF-Hand superfamily protein; [PTHR23050] CALCIUM BINDING PROTEIN; [PF13833] EF-hand domain pair; [PTHR23050:SF90] PROBABLE CALCIUM-BINDING PROTEIN CML9; [GO:0005509] calcium ion binding 208.57 0.5316
135 Mapoly0016s0206 [GO:0005515] protein binding; [PF14560] Ubiquitin-like domain; [PF01302] CAP-Gly domain; [KOG3206] Alpha-tubulin folding cofactor B; [PTHR18916] DYNACTIN 1-RELATED MICROTUBULE-BINDING 211.87 0.5441
136 Mapoly0025s0134 [GO:0005737] cytoplasm; [K08336] autophagy-related protein 12; [KOG3439] Protein conjugation factor involved in autophagy; [PTHR13385] AUTOPHAGY PROTEIN 12; [GO:0000045] autophagic vacuole assembly; [PF04110] Ubiquitin-like autophagy protein Apg12 211.94 0.5254
137 Mapoly0096s0007 - 213.00 0.5523
138 Mapoly0022s0028 [GO:0003677] DNA binding; [PF00249] Myb-like DNA-binding domain; [PF00538] linker histone H1 and H5 family; [GO:0003682] chromatin binding; [PTHR21717] TELOMERIC REPEAT BINDING PROTEIN; [GO:0000786] nucleosome; [GO:0005634] nucleus; [GO:0006334] nucleosome assembly 217.25 0.5070
139 Mapoly0127s0022 [GO:0003950] NAD+ ADP-ribosyltransferase activity; [PTHR21328] POLY (ADP-RIBOSE) POLYMERASE FAMILY, MEMBER (PARP); [PF00644] Poly(ADP-ribose) polymerase catalytic domain 217.39 0.4703
140 Mapoly0031s0059 [KOG0381] HMG box-containing protein; [PF00505] HMG (high mobility group) box; [PTHR13711] SWI/SNF-RELATED CHROMATIN BINDING PROTEIN 218.00 0.4817
141 Mapoly0105s0058 [PF13855] Leucine rich repeat; [GO:0005515] protein binding; [PTHR24365] TOLL-LIKE RECEPTOR; [PF00612] IQ calmodulin-binding motif 218.46 0.5617
142 Mapoly0074s0051 [GO:0000287] magnesium ion binding; [PTHR11902] ENOLASE; [PF03952] Enolase, N-terminal domain; [GO:0004634] phosphopyruvate hydratase activity; [GO:0006096] glycolysis; [PF00113] Enolase, C-terminal TIM barrel domain; [4.2.1.11] Phosphopyruvate hydratase.; [GO:0000015] phosphopyruvate hydratase complex; [K01689] enolase [EC:4.2.1.11]; [KOG2670] Enolase 221.34 0.5471
143 Mapoly0108s0011 [PF12774] Hydrolytic ATP binding site of dynein motor region D1; [PF12780] P-loop containing dynein motor region D4; [GO:0005524] ATP binding; [K10414] dynein heavy chain 2, cytosolic; [PF12775] P-loop containing dynein motor region D3; [GO:0030286] dynein complex; [PTHR10676:SF34] CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1; [PTHR10676] DYNEIN HEAVY CHAIN FAMILY PROTEIN; [PF08385] Dynein heavy chain, N-terminal region 1; [PF03028] Dynein heavy chain and region D6 of dynein motor; [PF07728] AAA domain (dynein-related subfamily); [GO:0016887] ATPase activity; [KOG3595] Dyneins, heavy chain; [PF12777] Microtubule-binding stalk of dynein motor; [GO:0007018] microtubule-based movement; [PF08393] Dynein heavy chain, N-terminal region 2; [PF12781] ATP-binding dynein motor region D5; [GO:0042384] cilium assembly; [GO:0003777] microtubule motor activity 223.45 0.5327
144 Mapoly0022s0126 [PTHR23314] SPERM-ASSOCIATED ANTIGEN 6 (ARMADILLO REPEAT-CONTAINING); [PF00514] Armadillo/beta-catenin-like repeat; [GO:0005515] protein binding; [KOG0166] Karyopherin (importin) alpha 224.04 0.5454
145 Mapoly0002s0154 - 224.66 0.5578
146 Mapoly0061s0142 - 227.26 0.4920
147 Mapoly0035s0042 [KOG3197] Predicted hydrolases of HD superfamily; [PTHR11845:SF14] UNCHARACTERIZED; [K07023] putative hydrolases of HD superfamily; [PF13023] HD domain; [PTHR11845] UNCHARACTERIZED 228.95 0.4857
148 Mapoly0059s0096 [PF05250] Uncharacterised protein family (UPF0193) 230.48 0.5229
149 Mapoly0054s0080 - 231.78 0.5212
150 Mapoly0029s0119 - 231.98 0.5434
151 Mapoly0031s0077 - 232.28 0.4111
152 Mapoly0032s0117 [PF06294] Domain of Unknown Function (DUF1042); [PTHR12509] SPERMATOGENESIS-ASSOCIATED 4-RELATED 234.53 0.5688
153 Mapoly0014s0167 [PF12317] Intraflagellar transport complex B protein 46 C terminal; [PTHR13376:SF0] SUBFAMILY NOT NAMED; [GO:0042073] intraflagellar transport; [PTHR13376] UNCHARACTERIZED 235.46 0.5604
154 Mapoly0016s0030 - 236.22 0.5145
155 Mapoly0003s0128 - 236.55 0.5283
156 Mapoly0192s0003 [PTHR31540] FAMILY NOT NAMED 237.62 0.5489
157 Mapoly0037s0066 [PTHR12771] ENGULFMENT AND CELL MOTILITY; [GO:0006909] phagocytosis; [GO:0005856] cytoskeleton; [PF04727] ELMO/CED-12 family 237.80 0.4255
158 Mapoly0062s0046 [PTHR12203] KDEL (LYS-ASP-GLU-LEU) CONTAINING - RELATED; [KOG2458] Endoplasmic reticulum protein EP58, contains filamin rod domain and KDEL motif; [PF05686] Glycosyl transferase family 90 238.95 0.5270
159 Mapoly0012s0012 [GO:0055114] oxidation-reduction process; [PF00175] Oxidoreductase NAD-binding domain; [PF00258] Flavodoxin; [PTHR19384] FLAVODOXIN-RELATED; [GO:0016491] oxidoreductase activity; [PF00667] FAD binding domain; [PTHR19384:SF10] NADPH FAD OXIDOREDUCTASE; [KOG1159] NADP-dependent flavoprotein reductase; [GO:0010181] FMN binding 239.00 0.5443
160 Mapoly0052s0034 - 239.14 0.5650
161 Mapoly0016s0171 [KOG0027] Calmodulin and related proteins (EF-Hand superfamily) 239.68 0.5203
162 Mapoly0030s0066 [PTHR31469] FAMILY NOT NAMED 241.31 0.5458
163 Mapoly1089s0002 [K09422] myb proto-oncogene protein, plant; [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding 242.18 0.4977
164 Mapoly0025s0008 [PTHR11985:SF1] GLYCEROL-3-PHOSPHATE DEHYDROGENASE-RELATED; [GO:0055114] oxidation-reduction process; [PF01266] FAD dependent oxidoreductase; [KOG0042] Glycerol-3-phosphate dehydrogenase; [GO:0016491] oxidoreductase activity; [PTHR11985] GLYCEROL-3-PHOSPHATE DEHYDROGENASE; [1.1.5.3] Glycerol-3-phosphate dehydrogenase.; [K00111] glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 243.39 0.5002
165 Mapoly0003s0083 [PF13855] Leucine rich repeat; [PF13516] Leucine Rich repeat; [GO:0005515] protein binding 247.63 0.5055
166 Mapoly0051s0003 - 249.64 0.4322
167 Mapoly0811s0001 [PF00249] Myb-like DNA-binding domain; [GO:0003682] chromatin binding; [PTHR12802] SWI/SNF COMPLEX-RELATED 251.22 0.4764
168 Mapoly0097s0036 [GO:0051087] chaperone binding; [PF02179] BAG domain 252.82 0.5390
169 Mapoly0013s0200 [PF06565] Repeat of unknown function (DUF1126); [PTHR12086] EF-HAND DOMAIN (C-TERMINAL) CONTAINING PROTEIN; [KOG0043] Uncharacterized conserved protein, contains DM10 domain 253.41 0.5369
170 Mapoly0095s0059 [PF05050] Methyltransferase FkbM domain 255.14 0.5265
171 Mapoly0093s0043 - 257.60 0.5545
172 Mapoly0094s0045 [GO:0048046] apoplast; [GO:0016762] xyloglucan:xyloglucosyl transferase activity; [GO:0006073] cellular glucan metabolic process; [PTHR31062] FAMILY NOT NAMED; [PF06955] Xyloglucan endo-transglycosylase (XET) C-terminus; [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [GO:0005975] carbohydrate metabolic process; [PF00722] Glycosyl hydrolases family 16; [GO:0005618] cell wall 257.71 0.5150
173 Mapoly0012s0125 [PTHR15599] RTDR1 259.46 0.5299
174 Mapoly0137s0026 [GO:0005515] protein binding; [PTHR14885] UNCHARACTERIZED; [PF00400] WD domain, G-beta repeat 260.64 0.5506
175 Mapoly0124s0025 [PF08609] Nucleotide exchange factor Fes1; [KOG2160] Armadillo/beta-catenin-like repeat-containing protein; [PTHR19316] PROTEIN FOLDING REGULATOR; [K14001] nucleotide exchange factor SIL1 262.95 0.4846
176 Mapoly0072s0044 - 263.50 0.5393
177 Mapoly0030s0062 [PF04969] CS domain; [PTHR12356] NUCLEAR MOVEMENT PROTEIN NUDC; [KOG2265] Nuclear distribution protein NUDC 265.86 0.5302
178 Mapoly0054s0111 [KOG3371] Uncharacterized conserved protein; [PTHR15854] THAP4 PROTEIN; [PF08768] Domain of unknown function (DUF1794) 269.71 0.5220
179 Mapoly0002s0185 [GO:0046836] glycolipid transport; [PF08718] Glycolipid transfer protein (GLTP); [GO:0005737] cytoplasm; [PTHR10219] GLYCOLIPID TRANSFER PROTEIN-RELATED; [GO:0051861] glycolipid binding; [KOG4189] Uncharacterized conserved protein; [GO:0017089] glycolipid transporter activity 271.08 0.4979
180 Mapoly0006s0275 - 271.26 0.3178
181 Mapoly0123s0012 [KOG0048] Transcription factor, Myb superfamily; [PF00249] Myb-like DNA-binding domain; [PTHR10641] MYB-LIKE DNA-BINDING PROTEIN MYB; [GO:0003682] chromatin binding 272.31 0.4710
182 Mapoly0051s0102 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [KOG0243] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [K10395] kinesin family member 4/7/21/27; [GO:0003777] microtubule motor activity 273.76 0.5593
183 Mapoly0031s0087 - 275.00 0.5379
184 Mapoly0038s0031 [GO:0005874] microtubule; [PF02970] Tubulin binding cofactor A; [GO:0007021] tubulin complex assembly; [PTHR21500] TUBULIN-SPECIFIC CHAPERONE A; [KOG3470] Beta-tubulin folding cofactor A; [PTHR21500:SF0] SUBFAMILY NOT NAMED; [GO:0051082] unfolded protein binding 275.82 0.5333
185 Mapoly0153s0020 [PTHR23359] NUCLEOTIDE KINASE; [GO:0005524] ATP binding; [K00939] adenylate kinase [EC:2.7.4.3]; [GO:0019205] nucleobase-containing compound kinase activity; [GO:0006139] nucleobase-containing compound metabolic process; [KOG3079] Uridylate kinase/adenylate kinase; [PF00406] Adenylate kinase; [2.7.4.3] Adenylate kinase. 276.71 0.5138
186 Mapoly0130s0025 [3.2.1.52] Beta-N-acetylhexosaminidase.; [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [GO:0005975] carbohydrate metabolic process; [K12373] hexosaminidase [EC:3.2.1.52]; [PTHR22600] BETA-HEXOSAMINIDASE; [KOG2499] Beta-N-acetylhexosaminidase; [PF00728] Glycosyl hydrolase family 20, catalytic domain; [PF14845] beta-acetyl hexosaminidase like; [PTHR22600:SF4] gb def: Beta-hexosaminidase (EC 3.2.1.52) 278.25 0.3927
187 Mapoly0056s0014 [GO:0016021] integral to membrane; [KOG3574] Acetyl-CoA transporter; [GO:0008521] acetyl-CoA transporter activity; [PTHR12778:SF3] SOLUTE CARRIER FAMILY 33 (ACETYL-COA TRANSPORTER); [PF13000] Acetyl-coenzyme A transporter 1; [PTHR12778] SOLUTE CARRIER FAMILY 33 (ACETYL-COA TRANSPORTER)-RELATED 278.60 0.4946
188 Mapoly0075s0061 - 278.60 0.5329
189 Mapoly0155s0020 - 281.60 0.3336
190 Mapoly0096s0052 [PTHR16275] FAMILY NOT NAMED 281.83 0.5312
191 Mapoly0140s0027 - 282.10 0.5437
192 Mapoly0014s0114 [KOG2061] Uncharacterized MYND Zn-finger protein; [PF04194] Programmed cell death protein 2, C-terminal putative domain; [GO:0005737] cytoplasm; [PTHR12298] PCDC2 (PROGRAMMED CELL DEATH PROTEIN 2)-RELATED 282.14 0.5328
193 Mapoly0001s0288 [KOG3809] Microtubule-binding protein MIP-T3; [PTHR31363:SF0] SUBFAMILY NOT NAMED; [GO:0008017] microtubule binding; [PF10243] Microtubule-binding protein MIP-T3; [PTHR31363] FAMILY NOT NAMED 282.69 0.5267
194 Mapoly0020s0076 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [GO:0008270] zinc ion binding; [KOG0279] G protein beta subunit-like protein; [PTHR22844] F-BOX AND WD40 DOMAIN PROTEIN; [GO:0006468] protein phosphorylation; [PF14634] zinc-RING finger domain; [PF00400] WD domain, G-beta repeat 284.07 0.4836
195 Mapoly0005s0131 - 285.24 0.5171
196 Mapoly0001s0515 [PF04844] Transcriptional repressor, ovate 285.32 0.5124
197 Mapoly0071s0102 [PF03645] Tctex-1 family; [PTHR21255:SF7] SUBFAMILY NOT NAMED; [PTHR21255] T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN; [KOG4108] Dynein light chain 285.98 0.5404
198 Mapoly0077s0050 - 288.22 0.5408
199 Mapoly0098s0049 [GO:0005507] copper ion binding; [GO:0009055] electron carrier activity; [PF02298] Plastocyanin-like domain 290.23 0.4782
200 Mapoly0004s0026 [PTHR32133] FAMILY NOT NAMED; [GO:0005515] protein binding; [PF00646] F-box domain 294.59 0.4561