Guide Gene
- Gene ID
- Mapoly0078s0040
- Organism
- Marchantia polymorpha
- Platform ID
- Mpo
- Description
- -
Coexpressed Gene List
Marchantia polymorphaRank Gene ID Description MR PCC Guide Mapoly0078s0040 - 0.00 1.0000 1 Mapoly0098s0037 [PTHR13043] EXOCYST COMPLEX COMPONENT SEC5; [GO:0000145] exocyst; [GO:0006893] Golgi to plasma membrane transport; [PF15469] Exocyst complex component Sec5; [KOG2347] Sec5 subunit of exocyst complex 1.00 0.8681 2 Mapoly0009s0222 [PTHR21506] COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6; [PF06419] Conserved oligomeric complex COG6; [GO:0006891] intra-Golgi vesicle-mediated transport; [GO:0017119] Golgi transport complex; [KOG3758] Uncharacterized conserved protein 2.65 0.7861 3 Mapoly0065s0070 [PF00225] Kinesin motor domain; [KOG0239] Kinesin (KAR3 subfamily); [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 3.46 0.8026 4 Mapoly0146s0035 [GO:0008168] methyltransferase activity; [PTHR10108] METHYLTRANSFERASE; [PF03141] Putative S-adenosyl-L-methionine-dependent methyltransferase 3.46 0.8060 5 Mapoly0038s0024 [PTHR19878] AUTOPHAGY PROTEIN 16-LIKE 4.69 0.8150 6 Mapoly0031s0124 [GO:0005515] protein binding; [PTHR22847] WD40 REPEAT PROTEIN; [KOG4462] WASP-interacting protein VRP1/WIP, contains WH2 domain; [PF00400] WD domain, G-beta repeat 8.06 0.7925 7 Mapoly0072s0011 [PF01602] Adaptin N terminal region; [PTHR22780] ADAPTIN, ALPHA/GAMMA/EPSILON; [GO:0016192] vesicle-mediated transport; [KOG1077] Vesicle coat complex AP-2, alpha subunit; [PF02883] Adaptin C-terminal domain; [PF02296] Alpha adaptin AP2, C-terminal domain; [GO:0030131] clathrin adaptor complex; [GO:0006886] intracellular protein transport; [GO:0030117] membrane coat; [PTHR22780:SF4] ADAPTER-RELATED PROTEIN COMPLEX 2 ALPHA 1 SUBUNIT (ALPHA-ADAPTIN A); [K11824] AP-2 complex subunit alpha 10.95 0.7812 8 Mapoly0170s0008 [K06111] exocyst complex component 4; [GO:0006904] vesicle docking involved in exocytosis; [PF04048] Sec8 exocyst complex component specific domain; [GO:0000145] exocyst; [PTHR14146] EXOCYST COMPLEX COMPONENT 4; [GO:0015031] protein transport 11.40 0.7588 9 Mapoly0167s0007 [PF12783] Guanine nucleotide exchange factor in Golgi transport N-terminal; [GO:0015031] protein transport; [PTHR10663] GUANYL-NUCLEOTIDE EXCHANGE FACTOR; [KOG1848] Uncharacterized conserved protein 12.00 0.7875 10 Mapoly0086s0049 [PF01602] Adaptin N terminal region; [GO:0005737] cytoplasm; [GO:0016192] vesicle-mediated transport; [PF07718] Coatomer beta C-terminal region; [PF14806] Coatomer beta subunit appendage platform; [GO:0030126] COPI vesicle coat; [KOG1058] Vesicle coat complex COPI, beta subunit; [PTHR10635] COATOMER SUBUNIT BETA; [GO:0006886] intracellular protein transport; [GO:0030117] membrane coat; [GO:0005198] structural molecule activity 12.41 0.7559 11 Mapoly0090s0047 [PF07719] Tetratricopeptide repeat; [PF13371] Tetratricopeptide repeat; [PF13414] TPR repeat; [KOG4162] Predicted calmodulin-binding protein; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR 13.86 0.7391 12 Mapoly0058s0053 [PF04791] LMBR1-like membrane protein; [K14617] LMBR1 domain-containing protein 1; [PTHR31652] FAMILY NOT NAMED 15.10 0.7276 13 Mapoly0002s0178 [K11826] AP-2 complex subunit mu-1; [GO:0016192] vesicle-mediated transport; [GO:0005515] protein binding; [PTHR11998] CLATHRIN COAT ASSEMBLY PROTEIN; [PF00928] Adaptor complexes medium subunit family; [KOG0938] Adaptor complexes medium subunit family; [GO:0030131] clathrin adaptor complex; [GO:0006886] intracellular protein transport 16.91 0.7083 14 Mapoly0022s0125 [PTHR19876:SF2] COATOMER BETA SUBUNIT; [GO:0016192] vesicle-mediated transport; [KOG0276] Vesicle coat complex COPI, beta' subunit; [GO:0005515] protein binding; [PTHR19876] COATOMER; [PF04053] Coatomer WD associated region; [GO:0006886] intracellular protein transport; [GO:0030117] membrane coat; [GO:0005198] structural molecule activity; [PF00400] WD domain, G-beta repeat 16.91 0.7502 15 Mapoly0061s0057 [PF02209] Villin headpiece domain; [PTHR11977:SF24] GELSOLIN-RELATED; [KOG0443] Actin regulatory proteins (gelsolin/villin family); [PTHR11977] VILLIN; [GO:0003779] actin binding; [GO:0007010] cytoskeleton organization; [PF00626] Gelsolin repeat 19.90 0.7345 16 Mapoly0003s0046 [GO:0016020] membrane; [PTHR12961] CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2; [GO:0015031] protein transport; [KOG2307] Low density lipoprotein receptor; [GO:0007030] Golgi organization; [PF06148] COG (conserved oligomeric Golgi) complex component, COG2; [PF12022] Domain of unknown function (DUF3510) 20.83 0.7463 17 Mapoly0007s0005 [PF06957] Coatomer (COPI) alpha subunit C-terminus; [GO:0016192] vesicle-mediated transport; [K05236] coatomer protein complex, subunit alpha (xenin); [KOG0292] Vesicle coat complex COPI, alpha subunit; [GO:0005515] protein binding; [PTHR19876:SF1] COATOMER ALPHA SUBUNIT; [PTHR19876] COATOMER; [GO:0030126] COPI vesicle coat; [PF04053] Coatomer WD associated region; [GO:0006886] intracellular protein transport; [GO:0030117] membrane coat; [GO:0005198] structural molecule activity; [PF00400] WD domain, G-beta repeat 20.98 0.7104 18 Mapoly0107s0040 [PF02219] Methylenetetrahydrofolate reductase; [K00297] methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20]; [1.5.1.20] Methylenetetrahydrofolate reductase (NAD(P)H).; [KOG0564] 5,10-methylenetetrahydrofolate reductase; [GO:0055114] oxidation-reduction process; [PTHR21091] METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED; [PTHR21091:SF31] PREDICTED PROTEIN; [GO:0004489] methylenetetrahydrofolate reductase (NADPH) activity; [GO:0006555] methionine metabolic process 26.50 0.7024 19 Mapoly0059s0025 [PTHR32227] FAMILY NOT NAMED; [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [GO:0005975] carbohydrate metabolic process; [PF07983] X8 domain; [PF00332] Glycosyl hydrolases family 17 27.04 0.6797 20 Mapoly0012s0190 [GO:0003723] RNA binding; [GO:0005524] ATP binding; [GO:0003774] motor activity; [PTHR13140] MYOSIN; [PF00642] Zinc finger C-x8-C-x5-C-x3-H type (and similar); [PF01843] DIL domain; [GO:0005515] protein binding; [KOG0160] Myosin class V heavy chain; [PF00612] IQ calmodulin-binding motif; [PF02736] Myosin N-terminal SH3-like domain; [PF00013] KH domain; [GO:0046872] metal ion binding; [PF00063] Myosin head (motor domain); [GO:0016459] myosin complex 27.66 0.7355 21 Mapoly0059s0098 - 27.98 0.7011 22 Mapoly0100s0023 [GO:0005086] ARF guanyl-nucleotide exchange factor activity; [PF12783] Guanine nucleotide exchange factor in Golgi transport N-terminal; [PTHR10663] GUANYL-NUCLEOTIDE EXCHANGE FACTOR; [PF01369] Sec7 domain; [GO:0032012] regulation of ARF protein signal transduction; [KOG0928] Pattern-formation protein/guanine nucleotide exchange factor 28.46 0.7601 23 Mapoly0041s0113 [KOG1912] WD40 repeat protein; [PTHR14593] FAMILY NOT NAMED 28.57 0.7529 24 Mapoly0111s0055 [PF10291] Muniscin C-terminal mu homology domain 29.39 0.6649 25 Mapoly0005s0083 [PF01602] Adaptin N terminal region; [GO:0016192] vesicle-mediated transport; [GO:0030126] COPI vesicle coat; [GO:0006886] intracellular protein transport; [GO:0030117] membrane coat; [KOG1078] Vesicle coat complex COPI, gamma subunit; [PF08752] Coatomer gamma subunit appendage platform subdomain; [GO:0005198] structural molecule activity; [PTHR10261] COATOMER SUBUNIT GAMMA 31.40 0.6935 26 Mapoly0224s0002 - 31.61 0.7019 27 Mapoly0102s0015 [KOG1187] Serine/threonine protein kinase; [PF13516] Leucine Rich repeat; [PF07714] Protein tyrosine kinase; [PF08263] Leucine rich repeat N-terminal domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 32.40 0.7057 28 Mapoly0081s0054 [PF13855] Leucine rich repeat; [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF13516] Leucine Rich repeat; [PF00069] Protein kinase domain; [PF08263] Leucine rich repeat N-terminal domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PF12799] Leucine Rich repeats (2 copies); [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 33.94 0.6960 29 Mapoly0186s0001 [PF08263] Leucine rich repeat N-terminal domain; [PTHR32093] FAMILY NOT NAMED 33.94 0.6745 30 Mapoly0087s0075 [PF09735] Membrane-associated apoptosis protein; [PTHR12093] FAMILY NOT NAMED; [KOG1917] Membrane-associated hematopoietic protein 34.86 0.7427 31 Mapoly0058s0074 [GO:0009058] biosynthetic process; [PF00534] Glycosyl transferases group 1; [PTHR12526] GLYCOSYLTRANSFERASE 35.50 0.6893 32 Mapoly0025s0059 [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [GO:0005975] carbohydrate metabolic process; [PF00759] Glycosyl hydrolase family 9; [PTHR22298] ENDO-1,4-BETA-GLUCANASE 39.76 0.6377 33 Mapoly0012s0079 [GO:0008168] methyltransferase activity; [PTHR10108] METHYLTRANSFERASE; [PF03141] Putative S-adenosyl-L-methionine-dependent methyltransferase 39.95 0.6629 34 Mapoly0119s0040 [PF03798] TLC domain; [KOG1607] Protein transporter of the TRAM (translocating chain-associating membrane) superfamily; [PTHR12560:SF5] gb def: lagl protein [suberites domuncula]; [GO:0016021] integral to membrane; [PTHR12560] LONGEVITY ASSURANCE FACTOR 1 (LAG1) 41.89 0.5864 35 Mapoly0005s0150 [GO:0008652] cellular amino acid biosynthetic process; [PF08267] Cobalamin-independent synthase, N-terminal domain; [GO:0008270] zinc ion binding; [PTHR30519:SF0] 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; [GO:0009086] methionine biosynthetic process; [K00549] 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]; [PF01717] Cobalamin-independent synthase, Catalytic domain; [2.1.1.14] 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase.; [PTHR30519] 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; [KOG2263] Methionine synthase II (cobalamin-independent); [GO:0003871] 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity 45.60 0.6329 36 Mapoly0006s0183 [PF03465] eRF1 domain 3; [KOG0688] Peptide chain release factor 1 (eRF1); [K03265] peptide chain release factor eRF subunit 1; [GO:0005737] cytoplasm; [PF03463] eRF1 domain 1; [PTHR10113] PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1; [PF03464] eRF1 domain 2; [GO:0006415] translational termination; [GO:0016149] translation release factor activity, codon specific 46.48 0.6825 37 Mapoly0015s0063 - 46.73 0.6664 38 Mapoly0121s0043 [PF11145] Protein of unknown function (DUF2921) 47.05 0.6451 39 Mapoly0088s0018 [GO:0008060] ARF GTPase activator activity; [PTHR23180:SF35] PREDICTED: SIMILAR TO G PROTEIN-COUPLED RECEPTOR KINASE INTERACTOR 1, PARTIAL; [KOG0704] ADP-ribosylation factor GTPase activator; [PTHR23180] CENTAURIN/ARF; [GO:0008270] zinc ion binding; [GO:0032312] regulation of ARF GTPase activity; [PF01412] Putative GTPase activating protein for Arf; [K12492] ADP-ribosylation factor GTPase-activating protein 1 51.72 0.6294 40 Mapoly0178s0015 [PTHR16220:SF0] SUBFAMILY NOT NAMED; [PTHR16220] WD REPEAT PROTEIN 8-RELATED; [GO:0005515] protein binding; [KOG4497] Uncharacterized conserved protein WDR8, contains WD repeats; [PF00400] WD domain, G-beta repeat 51.96 0.6488 41 Mapoly0049s0006 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 53.27 0.6422 42 Mapoly0002s0132 - 53.54 0.6580 43 Mapoly0002s0295 [PF01602] Adaptin N terminal region; [GO:0016192] vesicle-mediated transport; [PTHR11134] ADAPTER-RELATED PROTEIN COMPLEX, BETA SUBUNIT; [PF02883] Adaptin C-terminal domain; [PF09066] Beta2-adaptin appendage, C-terminal sub-domain; [KOG1061] Vesicle coat complex AP-1/AP-2/AP-4, beta subunit; [GO:0030131] clathrin adaptor complex; [GO:0006886] intracellular protein transport; [GO:0030117] membrane coat; [K12392] AP-1 complex subunit beta-1; [PTHR11134:SF3] ADAPTER-RELATED PROTEIN COMPLEX 1, BETA SUBUNIT 54.22 0.6990 44 Mapoly0045s0011 [GO:0005524] ATP binding; [6.1.1.10] Methionine--tRNA ligase.; [GO:0000166] nucleotide binding; [PF01588] Putative tRNA binding domain; [PTHR11946] ISOLEUCYL, LEUCYL, TYROSYL, VALYL AND METHIONYL-TRNA SYNTHETASES; [GO:0000049] tRNA binding; [PF09334] tRNA synthetases class I (M); [GO:0006418] tRNA aminoacylation for protein translation; [GO:0004812] aminoacyl-tRNA ligase activity; [K01874] methionyl-tRNA synthetase [EC:6.1.1.10]; [KOG1247] Methionyl-tRNA synthetase 55.18 0.7086 45 Mapoly0014s0109 [PTHR32227] FAMILY NOT NAMED; [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [GO:0005975] carbohydrate metabolic process; [PF07983] X8 domain; [PF00332] Glycosyl hydrolases family 17 55.72 0.6239 46 Mapoly0149s0034 [PTHR32227] FAMILY NOT NAMED; [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [GO:0005975] carbohydrate metabolic process; [PF00332] Glycosyl hydrolases family 17 56.12 0.6573 47 Mapoly0098s0006 - 58.22 0.6267 48 Mapoly0032s0137 [PF00264] Common central domain of tyrosinase; [PF12142] Polyphenol oxidase middle domain; [GO:0055114] oxidation-reduction process; [PTHR11474] TYROSINASE; [GO:0016491] oxidoreductase activity; [GO:0008152] metabolic process; [GO:0004097] catechol oxidase activity; [PF12143] Protein of unknown function (DUF_B2219) 59.40 0.5992 49 Mapoly0077s0054 [PF07919] Gryzun, putative trafficking through Golgi; [PTHR14374] FOIE GRAS; [PF11817] Foie gras liver health family 1 61.71 0.7018 50 Mapoly0054s0015 [GO:0006904] vesicle docking involved in exocytosis; [GO:0016192] vesicle-mediated transport; [PTHR11679] VESICLE PROTEIN SORTING-ASSOCIATED; [KOG1302] Vacuolar sorting protein VPS33/slp1 (Sec1 family); [PTHR11679:SF1] VACUOLAR PROTEIN SORTING (VPS33); [PF00995] Sec1 family 61.73 0.5638 51 Mapoly0015s0089 [GO:0005524] ATP binding; [KOG0335] ATP-dependent RNA helicase; [3.6.4.13] RNA helicase.; [K11594] ATP-dependent RNA helicase [EC:3.6.4.13]; [PF00270] DEAD/DEAH box helicase; [PTHR24031:SF9] HELICASE CONSERVED C-TERMINAL DOMAIN, PUTATIVE; [PF00271] Helicase conserved C-terminal domain; [PTHR24031] FAMILY NOT NAMED; [GO:0003676] nucleic acid binding 62.92 0.6878 52 Mapoly0015s0202 [PF00018] SH3 domain; [GO:0005515] protein binding; [PTHR12602] FORMIN BINDING PROTEIN AND RELATED PROTEINS 62.93 0.7061 53 Mapoly0065s0029 [PF13950] UDP-glucose 4-epimerase C-term subunit; [K01784] UDP-glucose 4-epimerase [EC:5.1.3.2]; [PF01370] NAD dependent epimerase/dehydratase family; [GO:0003824] catalytic activity; [KOG1371] UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase; [5.1.3.2] UDP-glucose 4-epimerase.; [GO:0050662] coenzyme binding; [PTHR10366] NAD DEPENDENT EPIMERASE/DEHYDRATASE 64.75 0.6162 54 Mapoly0083s0023 [PF02893] GRAM domain; [KOG1032] Uncharacterized conserved protein, contains GRAM domain; [PTHR23319] UNCHARACTERIZED 66.57 0.5804 55 Mapoly0022s0045 [PTHR10121:SF0] COATOMER SUBUNIT DELTA; [GO:0016192] vesicle-mediated transport; [GO:0005515] protein binding; [GO:0030126] COPI vesicle coat; [PF00928] Adaptor complexes medium subunit family; [KOG2635] Medium subunit of clathrin adaptor complex; [GO:0006890] retrograde vesicle-mediated transport, Golgi to ER; [GO:0030131] clathrin adaptor complex; [GO:0006886] intracellular protein transport; [PTHR10121] COATOMER SUBUNIT DELTA 66.97 0.6526 56 Mapoly0041s0033 [KOG4308] LRR-containing protein; [PF13516] Leucine Rich repeat; [PTHR24106] FAMILY NOT NAMED 68.37 0.5662 57 Mapoly0001s0140 [PF01852] START domain; [PTHR12136] STEROIDOGENIC ACUTE REGULATORY PROTEIN (STAR); [GO:0008289] lipid binding; [PF07059] Protein of unknown function (DUF1336) 68.98 0.6477 58 Mapoly0031s0138 [KOG1931] Putative transmembrane protein; [PTHR13251] EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1; [PF11817] Foie gras liver health family 1; [PF12584] Trafficking protein particle complex subunit 10, TRAPPC10 69.83 0.7081 59 Mapoly0079s0051 [PF13414] TPR repeat; [K00670] peptide alpha-N-acetyltransferase [EC:2.3.1.88]; [KOG1156] N-terminal acetyltransferase; [2.3.1.88] Peptide alpha-N-acetyltransferase.; [PTHR22767:SF2] N-TERMINAL ACETLYTRANSFERASE-RELATED; [PF12569] NMDA receptor-regulated protein 1; [PTHR22767] N-TERMINAL ACETLYTRANSFERASE-RELATED 69.99 0.6989 60 Mapoly0030s0155 [GO:0005086] ARF guanyl-nucleotide exchange factor activity; [PF09324] Domain of unknown function (DUF1981); [PF12783] Guanine nucleotide exchange factor in Golgi transport N-terminal; [KOG0929] Guanine nucleotide exchange factor; [PTHR10663] GUANYL-NUCLEOTIDE EXCHANGE FACTOR; [PF01369] Sec7 domain; [GO:0032012] regulation of ARF protein signal transduction 70.38 0.6874 61 Mapoly0120s0028 [KOG2215] Exocyst complex subunit; [PF08700] Vps51/Vps67; [PTHR21426] FAMILY NOT NAMED 70.99 0.6805 62 Mapoly0022s0120 [PTHR23323] VACUOLAR MEMBRANE PROTEIN RELATED; [PF00637] Region in Clathrin and VPS; [PF12451] Vacuolar protein sorting protein 11 C terminal; [GO:0016192] vesicle-mediated transport; [GO:0006886] intracellular protein transport; [PTHR23323:SF24] VACUOLAR MEMBRANE PROTEIN PEP5, 11; [KOG2114] Vacuolar assembly/sorting protein PEP5/VPS11 71.58 0.6275 63 Mapoly0073s0001 [PF00264] Common central domain of tyrosinase; [PF12142] Polyphenol oxidase middle domain; [GO:0055114] oxidation-reduction process; [PTHR11474] TYROSINASE; [GO:0016491] oxidoreductase activity; [GO:0008152] metabolic process; [GO:0004097] catechol oxidase activity; [PF12143] Protein of unknown function (DUF_B2219) 71.58 0.5922 64 Mapoly0002s0131 [PTHR19961] FIMBRIN/PLASTIN; [GO:0005515] protein binding; [PF00307] Calponin homology (CH) domain; [KOG0046] Ca2+-binding actin-bundling protein (fimbrin/plastin), EF-Hand protein superfamily 72.21 0.6470 65 Mapoly0186s0007 [PF07250] Glyoxal oxidase N-terminus; [PF09118] Domain of unknown function (DUF1929); [PTHR32208] FAMILY NOT NAMED 73.57 0.6198 66 Mapoly0035s0061 [KOG2056] Equilibrative nucleoside transporter protein; [PF01417] ENTH domain; [PTHR12276] EPSIN/ENT-RELATED 74.62 0.6408 67 Mapoly0087s0035 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [PTHR24115:SF105] SUBFAMILY NOT NAMED; [KOG0243] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 76.73 0.6788 68 Mapoly0022s0144 [GO:0006506] GPI anchor biosynthetic process; [PTHR14859] CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR; [PF03372] Endonuclease/Exonuclease/phosphatase family; [PTHR14859:SF0] SUBFAMILY NOT NAMED 77.39 0.6651 69 Mapoly0081s0052 - 79.20 0.6720 70 Mapoly0014s0213 [KOG1991] Nuclear transport receptor RANBP7/RANBP8 (importin beta superfamily); [PF08506] Cse1; [PF03810] Importin-beta N-terminal domain; [GO:0005515] protein binding; [PF03378] CAS/CSE protein, C-terminus; [PTHR10997:SF18] IMPORTIN 7, 8 (IMP7, 8) (RAN-BINDING PROTEIN 7, 8); [GO:0006886] intracellular protein transport; [PTHR10997] IMPORTIN-7, 8, 11; [GO:0008536] Ran GTPase binding 81.78 0.6487 71 Mapoly0016s0072 [GO:0005524] ATP binding; [GO:0004222] metalloendopeptidase activity; [PF01434] Peptidase family M41; [PTHR23076] METALLOPROTEASE M41 FTSH; [PF00004] ATPase family associated with various cellular activities (AAA); [GO:0006508] proteolysis 88.33 0.6769 72 Mapoly0045s0097 [GO:0030130] clathrin coat of trans-Golgi network vesicle; [PF00637] Region in Clathrin and VPS; [GO:0016192] vesicle-mediated transport; [PF09268] Clathrin, heavy-chain linker; [PF13838] Clathrin-H-link; [K04646] clathrin heavy chain; [GO:0006886] intracellular protein transport; [GO:0030132] clathrin coat of coated pit; [KOG0985] Vesicle coat protein clathrin, heavy chain; [PF01394] Clathrin propeller repeat; [GO:0005198] structural molecule activity; [PTHR10292] CLATHRIN HEAVY CHAIN 88.59 0.6892 73 Mapoly0064s0104 [PF13355] Protein of unknown function (DUF4101) 88.60 0.6694 74 Mapoly0036s0016 [GO:0006904] vesicle docking involved in exocytosis; [KOG2176] Exocyst complex, subunit SEC15; [PTHR12702:SF1] SEC15; [GO:0000145] exocyst; [PTHR12702] SEC15; [PF04091] Exocyst complex subunit Sec15-like 89.44 0.6567 75 Mapoly0096s0070 [GO:0055114] oxidation-reduction process; [PF00141] Peroxidase; [GO:0020037] heme binding; [PTHR31235] FAMILY NOT NAMED; [GO:0006979] response to oxidative stress; [GO:0004601] peroxidase activity 90.23 0.6146 76 Mapoly0004s0114 [PF03097] BRO1-like domain; [K12200] programmed cell death 6-interacting protein; [PTHR23030] PCD6 INTERACTING PROTEIN-RELATED; [KOG2220] Predicted signal transduction protein; [GO:0005515] protein binding; [PF13949] ALIX V-shaped domain binding to HIV; [PTHR23030:SF13] SUBFAMILY NOT NAMED 91.27 0.6520 77 Mapoly0014s0145 [GO:0008060] ARF GTPase activator activity; [GO:0005737] cytoplasm; [PTHR23180] CENTAURIN/ARF; [GO:0005515] protein binding; [GO:0008270] zinc ion binding; [KOG0521] Putative GTPase activating proteins (GAPs); [GO:0032312] regulation of ARF GTPase activity; [PF00169] PH domain; [PF01412] Putative GTPase activating protein for Arf; [PF03114] BAR domain; [PF12796] Ankyrin repeats (3 copies) 91.85 0.6129 78 Mapoly0019s0146 [K14288] exportin-T; [PTHR15952] EXPORTIN-T/LOS1; [KOG2021] Nuclear mRNA export factor receptor LOS1/Exportin-t (importin beta superfamily); [PF08389] Exportin 1-like protein 92.09 0.6295 79 Mapoly0015s0106 [PF04577] Protein of unknown function (DUF563); [PTHR20961] GLYCOSYLTRANSFERASE; [GO:0016757] transferase activity, transferring glycosyl groups; [PTHR20961:SF0] SUBFAMILY NOT NAMED 95.73 0.6064 80 Mapoly0016s0170 [PF13513] HEAT-like repeat; [PF03810] Importin-beta N-terminal domain; [GO:0006886] intracellular protein transport; [GO:0008536] Ran GTPase binding; [PTHR10527] IMPORTIN BETA; [KOG1241] Karyopherin (importin) beta 1; [K14293] importin subunit beta-1 96.69 0.6876 81 Mapoly0023s0169 - 97.58 0.5817 82 Mapoly0046s0052 [KOG0430] Xanthine dehydrogenase; [PTHR11908] XANTHINE DEHYDROGENASE; [GO:0055114] oxidation-reduction process; [PF01799] [2Fe-2S] binding domain; [PF01315] Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; [GO:0016491] oxidoreductase activity; [GO:0009055] electron carrier activity; [PF00941] FAD binding domain in molybdopterin dehydrogenase; [PF02738] Molybdopterin-binding domain of aldehyde dehydrogenase; [PF00111] 2Fe-2S iron-sulfur cluster binding domain; [PF03450] CO dehydrogenase flavoprotein C-terminal domain; [GO:0051536] iron-sulfur cluster binding; [GO:0046872] metal ion binding 98.40 0.6314 83 Mapoly0021s0072 [GO:0005085] guanyl-nucleotide exchange factor activity; [GO:0007264] small GTPase mediated signal transduction; [PTHR23317] DEDICATOR OF CYTOKINESIS (DOCK); [PF14429] C2 domain in Dock180 and Zizimin proteins; [PF06920] Dedicator of cytokinesis; [KOG1997] PH domain-containing protein 98.61 0.6796 84 Mapoly0113s0022 [PF01501] Glycosyl transferase family 8; [2.4.1.43] Polygalacturonate 4-alpha-galacturonosyltransferase.; [K13648] alpha-1,4-galacturonosyltransferase [EC:2.4.1.43]; [PTHR32116] FAMILY NOT NAMED; [GO:0016757] transferase activity, transferring glycosyl groups 99.01 0.6621 85 Mapoly0096s0051 [KOG2099] Glycogen phosphorylase; [2.4.1.1] Glycogen phosphorylase.; [GO:0005975] carbohydrate metabolic process; [K00688] starch phosphorylase [EC:2.4.1.1]; [PF00343] Carbohydrate phosphorylase; [PTHR11468] GLYCOGEN PHOSPHORYLASE; [PTHR11468:SF8] GLYCOGEN PHOSPHORYLASE; [GO:0008184] glycogen phosphorylase activity 99.28 0.6270 86 Mapoly0153s0030 [GO:0016651] oxidoreductase activity, acting on NAD(P)H; [GO:0055114] oxidation-reduction process; [PF00384] Molybdopterin oxidoreductase; [1.6.99.3] NADH dehydrogenase.; [PF13510] 2Fe-2S iron-sulfur cluster binding domain; [KOG2282] NADH-ubiquinone oxidoreductase, NDUFS1/75 kDa subunit; [GO:0016491] oxidoreductase activity; [PTHR11615] NITRATE, FROMATE, IRON DEHYDROGENASE; [GO:0051536] iron-sulfur cluster binding; [PF09326] Domain of unknown function (DUF1982); [1.6.5.3] NADH:ubiquinone reductase (H(+)-translocating).; [K03934] NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]; [PF10588] NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 100.74 0.5983 87 Mapoly0207s0007 [PTHR14387:SF0] SUBFAMILY NOT NAMED; [PTHR14387] THADA/DEATH RECEPTOR INTERACTING PROTEIN; [PF10350] Putative death-receptor fusion protein (DUF2428) 101.00 0.6430 88 Mapoly0151s0016 [PF08318] COG4 transport protein; [PTHR24016] FAMILY NOT NAMED; [PTHR24016:SF0] SUBFAMILY NOT NAMED; [KOG0412] Golgi transport complex COD1 protein 101.44 0.5500 89 Mapoly0016s0016 [PF07719] Tetratricopeptide repeat; [PF00569] Zinc finger, ZZ type; [PF13414] TPR repeat; [GO:0008270] zinc ion binding; [PF13424] Tetratricopeptide repeat; [GO:0005509] calcium ion binding; [PTHR23083] TETRATRICOPEPTIDE REPEAT PROTEIN, TPR; [PF13202] EF hand 101.53 0.5990 90 Mapoly0013s0072 [PTHR16092] SEC3/SYNTAXIN-RELATED; [PF09763] Exocyst complex component Sec3; [KOG2148] Exocyst protein Sec3; [PF15277] Exocyst complex component SEC3 N-terminal PIP2 binding PH 101.59 0.6171 91 Mapoly0028s0118 [PF04852] Protein of unknown function (DUF640); [PTHR31165] FAMILY NOT NAMED 105.76 0.6222 92 Mapoly0181s0003 [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 105.83 0.6045 93 Mapoly0052s0026 [GO:0008168] methyltransferase activity; [PTHR10108] METHYLTRANSFERASE; [PF03141] Putative S-adenosyl-L-methionine-dependent methyltransferase 106.96 0.6554 94 Mapoly0035s0137 [GO:0005643] nuclear pore; [PTHR10350:SF6] NUCLEOPORIN 155; [PF03177] Non-repetitive/WGA-negative nucleoporin C-terminal; [K14312] nuclear pore complex protein Nup155; [KOG1900] Nuclear pore complex, Nup155 component (D Nup154, sc Nup157/Nup170); [GO:0006913] nucleocytoplasmic transport; [PF08801] Nup133 N terminal like; [GO:0017056] structural constituent of nuclear pore; [PTHR10350] NUCLEAR PORE COMPLEX PROTEIN NUP155 107.32 0.6953 95 Mapoly1100s0003 [GO:0005524] ATP binding; [PTHR10046:SF23] LON PROTEASE HOMOLOG, MITOCHONDRIAL; [GO:0004176] ATP-dependent peptidase activity; [GO:0004252] serine-type endopeptidase activity; [PF02190] ATP-dependent protease La (LON) domain; [GO:0030163] protein catabolic process; [PTHR10046] ATP DEPENDENT LON PROTEASE FAMILY MEMBER; [GO:0006508] proteolysis 108.19 0.6485 96 Mapoly0004s0158 [GO:0033179] proton-transporting V-type ATPase, V0 domain; [3.6.3.14] H(+)-transporting two-sector ATPase.; [K02154] V-type H+-transporting ATPase subunit I [EC:3.6.3.14]; [PTHR11629] VACUOLAR PROTON ATPASES; [GO:0015078] hydrogen ion transmembrane transporter activity; [GO:0015991] ATP hydrolysis coupled proton transport; [PF01496] V-type ATPase 116kDa subunit family; [KOG2189] Vacuolar H+-ATPase V0 sector, subunit a 108.24 0.6231 97 Mapoly0156s0024 [PF08506] Cse1; [PF03810] Importin-beta N-terminal domain; [GO:0005515] protein binding; [KOG1992] Nuclear export receptor CSE1/CAS (importin beta superfamily); [PTHR10997:SF8] IMPORTIN-ALPHA RE-EXPORTER (CHROMOSOME SEGREGATION 1-LIKE PROTEIN); [PF03378] CAS/CSE protein, C-terminus; [GO:0006886] intracellular protein transport; [PTHR10997] IMPORTIN-7, 8, 11; [GO:0008536] Ran GTPase binding 109.41 0.6257 98 Mapoly0082s0076 [PF13855] Leucine rich repeat; [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF08263] Leucine rich repeat N-terminal domain; [PF00069] Protein kinase domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 109.60 0.6065 99 Mapoly0061s0020 [PTHR21576:SF2] UNCHARACTERIZED NODULIN-LIKE PROTEIN; [PF08161] NUC173 domain; [KOG1248] Uncharacterized conserved protein; [PTHR21576] UNCHARACTERIZED NODULIN-LIKE PROTEIN 111.24 0.6793 100 Mapoly0055s0072 [PTHR16254] POTASSIUM/PROTON ANTIPORTER-RELATED; [GO:0015299] solute:hydrogen antiporter activity; [GO:0016021] integral to membrane; [KOG1650] Predicted K+/H+-antiporter; [GO:0055085] transmembrane transport; [GO:0006813] potassium ion transport; [PF02254] TrkA-N domain; [GO:0006812] cation transport; [PF00999] Sodium/hydrogen exchanger family 111.64 0.6032 101 Mapoly0013s0180 [PF12329] TATA element modulatory factor 1 DNA binding; [PTHR13140] MYOSIN; [KOG4673] Transcription factor TMF, TATA element modulatory factor; [PF12325] TATA element modulatory factor 1 TATA binding 114.31 0.6497 102 Mapoly0091s0001 [PTHR14190:SF7] SUBFAMILY NOT NAMED; [PF04129] Vps52 / Sac2 family; [KOG1961] Vacuolar sorting protein VPS52/suppressor of actin Sac2; [PTHR14190] SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52 115.65 0.6187 103 Mapoly0006s0267 - 119.08 0.6036 104 Mapoly0053s0042 [KOG0978] E3 ubiquitin ligase involved in syntaxin degradation; [PTHR18921] MYOSIN HEAVY CHAIN - RELATED 119.20 0.6351 105 Mapoly0074s0011 [PTHR15486] ANCIENT UBIQUITOUS PROTEIN; [PF12710] haloacid dehalogenase-like hydrolase; [K13508] glycerol-3-phosphate acyltransferase [EC:2.3.1.15]; [PF01553] Acyltransferase; [GO:0016746] transferase activity, transferring acyl groups; [GO:0008152] metabolic process; [2.3.1.15] Glycerol-3-phosphate 1-O-acyltransferase. 119.29 0.6157 106 Mapoly0033s0139 - 119.58 0.6163 107 Mapoly0029s0100 [PF13513] HEAT-like repeat; [PF03810] Importin-beta N-terminal domain; [KOG2171] Karyopherin (importin) beta 3; [GO:0006886] intracellular protein transport; [GO:0008536] Ran GTPase binding; [PTHR10527:SF6] IMPORTIN-4 (IMPORTIN-4B)(RAN-BINDING PROTEIN 4); [PTHR10527] IMPORTIN BETA; [PF13646] HEAT repeats 121.13 0.6534 108 Mapoly0153s0002 [GO:0005524] ATP binding; [GO:0000166] nucleotide binding; [PF08264] Anticodon-binding domain of tRNA; [6.1.1.4] Leucine--tRNA ligase.; [PTHR11946] ISOLEUCYL, LEUCYL, TYROSYL, VALYL AND METHIONYL-TRNA SYNTHETASES; [K01869] leucyl-tRNA synthetase [EC:6.1.1.4]; [PF00133] tRNA synthetases class I (I, L, M and V); [KOG0437] Leucyl-tRNA synthetase; [GO:0006418] tRNA aminoacylation for protein translation; [GO:0004812] aminoacyl-tRNA ligase activity 123.21 0.6605 109 Mapoly0040s0042 - 125.28 0.6615 110 Mapoly0053s0083 [PF04998] RNA polymerase Rpb1, domain 5; [GO:0003677] DNA binding; [PF00623] RNA polymerase Rpb1, domain 2; [PTHR19376] DNA-DIRECTED RNA POLYMERASE; [KOG0262] RNA polymerase I, large subunit; [PF05000] RNA polymerase Rpb1, domain 4; [GO:0008270] zinc ion binding; [GO:0005634] nucleus; [PF04997] RNA polymerase Rpb1, domain 1; [GO:0006351] transcription, DNA-dependent; [K02999] DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6]; [GO:0003899] DNA-directed RNA polymerase activity; [PF04983] RNA polymerase Rpb1, domain 3; [2.7.7.6] DNA-directed RNA polymerase.; [PTHR19376:SF11] DNA-DIRECTED RNA POLYMERASE I LARGEST SUBUNIT 127.74 0.6816 111 Mapoly0062s0039 [PTHR10108:SF243] METHYLTRANSFERASE; [PF13450] NAD(P)-binding Rossmann-like domain; [PF02353] Mycolic acid cyclopropane synthetase; [PTHR10108] METHYLTRANSFERASE; [GO:0008610] lipid biosynthetic process; [K00574] cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79]; [2.1.1.79] Cyclopropane-fatty-acyl-phospholipid synthase. 130.15 0.6275 112 Mapoly0126s0034 [GO:0005524] ATP binding; [6.3.5.5] Carbamoyl-phosphate synthase (glutamine-hydrolyzing).; [K01955] carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]; [KOG0370] Multifunctional pyrimidine synthesis protein CAD (includes carbamoyl-phophate synthetase, aspartate transcarbamylase, and glutamine amidotransferase); [PF00289] Carbamoyl-phosphate synthase L chain, N-terminal domain; [PF02142] MGS-like domain; [GO:0008152] metabolic process; [PTHR11405] CARBAMOYLTRANSFERASE RELATED; [PF02787] Carbamoyl-phosphate synthetase large chain, oligomerisation domain; [GO:0003824] catalytic activity; [PF02786] Carbamoyl-phosphate synthase L chain, ATP binding domain 131.00 0.6553 113 Mapoly0002s0294 [PTHR24414] FAMILY NOT NAMED; [GO:0005515] protein binding; [KOG4693] Uncharacterized conserved protein, contains kelch repeat; [PF01344] Kelch motif; [PF00646] F-box domain 132.82 0.6176 114 Mapoly0013s0092 - 133.66 0.6083 115 Mapoly0070s0084 [PTHR12100] SEC10; [GO:0005737] cytoplasm; [GO:0048278] vesicle docking; [PF07393] Exocyst complex component Sec10; [PTHR12100:SF0] SUBFAMILY NOT NAMED; [KOG3745] Exocyst subunit - Sec10p; [GO:0006887] exocytosis 137.29 0.6577 116 Mapoly1342s0001 [KOG0157] Cytochrome P450 CYP4/CYP19/CYP26 subfamilies; [GO:0005506] iron ion binding; [GO:0055114] oxidation-reduction process; [GO:0016705] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; [GO:0020037] heme binding; [PTHR24298] FAMILY NOT NAMED; [PF00067] Cytochrome P450 137.52 0.5863 117 Mapoly0015s0011 [GO:0005524] ATP binding; [PF03461] TRCF domain; [PF00270] DEAD/DEAH box helicase; [GO:0006281] DNA repair; [PF00271] Helicase conserved C-terminal domain; [PF02559] CarD-like/TRCF domain; [KOG0344] ATP-dependent RNA helicase; [GO:0003676] nucleic acid binding; [PTHR14025] FAMILY NOT NAMED 139.55 0.6354 118 Mapoly0001s0292 [KOG1913] Regucalcin gene promoter region-related protein (RGPR); [GO:0048208] COPII vesicle coating; [PF12932] Vesicle coat trafficking protein Sec16 mid-region; [PTHR13402] RGPR-RELATED; [PF12931] Sec23-binding domain of Sec16 139.73 0.6641 119 Mapoly0006s0254 [PTHR13026:SF0] SUBFAMILY NOT NAMED; [PTHR13026] NNP-1 PROTEIN (NOVEL NUCLEAR PROTEIN 1) (NOP52); [GO:0030688] preribosome, small subunit precursor; [PF05997] Nucleolar protein,Nop52; [GO:0006364] rRNA processing 140.07 0.6380 120 Mapoly0032s0136 [PF00264] Common central domain of tyrosinase; [PF12142] Polyphenol oxidase middle domain; [GO:0055114] oxidation-reduction process; [PTHR11474] TYROSINASE; [GO:0016491] oxidoreductase activity; [GO:0008152] metabolic process; [GO:0004097] catechol oxidase activity; [PF12143] Protein of unknown function (DUF_B2219) 140.48 0.5180 121 Mapoly0187s0007 [PTHR12363] TRANSPORTIN 3 AND IMPORTIN 13; [PF03810] Importin-beta N-terminal domain; [GO:0006886] intracellular protein transport; [GO:0008536] Ran GTPase binding; [KOG2081] Nuclear transport regulator; [PF08389] Exportin 1-like protein 140.67 0.6677 122 Mapoly0024s0107 [PF07719] Tetratricopeptide repeat; [GO:0005515] protein binding; [PF13414] TPR repeat; [K03350] anaphase-promoting complex subunit 3; [KOG1126] DNA-binding cell division cycle control protein; [PF13181] Tetratricopeptide repeat; [PF00515] Tetratricopeptide repeat; [PTHR12558] CELL DIVISION CYCLE 16,23,27; [PTHR12558:SF11] CELL DIVISION CYCLE 27; [PF12895] Anaphase-promoting complex, cyclosome, subunit 3 142.30 0.6458 123 Mapoly0023s0010 [PF00132] Bacterial transferase hexapeptide (six repeats); [PF13450] NAD(P)-binding Rossmann-like domain; [PF00501] AMP-binding enzyme; [GO:0055114] oxidation-reduction process; [KOG1176] Acyl-CoA synthetase; [PF00199] Catalase; [GO:0004096] catalase activity; [PTHR22754] DISCO-INTERACTING PROTEIN 2 (DIP2)-RELATED; [GO:0020037] heme binding; [GO:0008152] metabolic process; [GO:0003824] catalytic activity 142.46 0.5140 124 Mapoly0095s0062 [PF13371] Tetratricopeptide repeat; [PF00514] Armadillo/beta-catenin-like repeat; [GO:0005515] protein binding; [PF13414] TPR repeat; [GO:0043531] ADP binding; [KOG4224] Armadillo repeat protein VAC8 required for vacuole fusion, inheritance and cytosol-to-vacuole protein targeting; [PTHR23315] BETA CATENIN-RELATED ARMADILLO REPEAT-CONTAINING; [PF00931] NB-ARC domain; [PF13646] HEAT repeats 143.89 0.5458 125 Mapoly0067s0045 [PTHR14187] ALPHA KINASE/ELONGATION FACTOR 2 KINASE; [GO:0005524] ATP binding; [K08292] elongation factor 2 kinase [EC:2.7.11.20]; [PTHR14187:SF3] ALPHA KINASE; [GO:0006468] protein phosphorylation; [2.7.11.20] [Elongation factor 2] kinase.; [GO:0004674] protein serine/threonine kinase activity; [PF02816] Alpha-kinase family 144.33 0.5399 126 Mapoly0049s0010 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 144.67 0.5427 127 Mapoly0056s0137 [PTHR13743] BEIGE/BEACH-RELATED; [GO:0005515] protein binding; [PTHR13743:SF16] SUBFAMILY NOT NAMED; [KOG1787] Kinase A-anchor protein Neurobeachin and related BEACH and WD40 repeat proteins; [PF02138] Beige/BEACH domain; [PF14844] PH domain associated with Beige/BEACH; [PF00400] WD domain, G-beta repeat 144.75 0.6504 128 Mapoly0071s0086 [KOG0623] Glutamine amidotransferase/cyclase; [PTHR21235:SF2] IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF (IGP SYNTHASE SUBUNIT HISF); [PTHR21235] IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF/H (IGP SYNTHASE SUBUNIT HISF/H); [GO:0000105] histidine biosynthetic process; [K01663] glutamine amidotransferase / cyclase [EC:2.4.2.- 4.1.3.-]; [PF00117] Glutamine amidotransferase class-I; [PF00977] Histidine biosynthesis protein; [4.1.3.-] Oxo-acid-lyases.; [2.4.2.-] Pentosyltransferases. 146.36 0.6532 129 Mapoly0006s0304 [KOG2033] Low density lipoprotein B-like protein; [PTHR31658:SF0] SUBFAMILY NOT NAMED; [PF08700] Vps51/Vps67; [PTHR31658] FAMILY NOT NAMED 147.74 0.6323 130 Mapoly0090s0030 [KOG0978] E3 ubiquitin ligase involved in syntaxin degradation 149.40 0.6464 131 Mapoly0103s0007 [PF03143] Elongation factor Tu C-terminal domain; [PF00009] Elongation factor Tu GTP binding domain; [GO:0003924] GTPase activity; [K03267] G1 to S phase transition protein; [PTHR23115] TRANSLATION FACTOR; [PTHR23115:SF36] EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR GTP-BINDING SUBUNIT (ERF2) (TRANSLATION RELEASE FACTOR 3) (ERF3) (ERF-3); [KOG0459] Polypeptide release factor 3; [GO:0005525] GTP binding; [PF03144] Elongation factor Tu domain 2 150.46 0.6344 132 Mapoly0003s0013 [KOG1187] Serine/threonine protein kinase; [PF07714] Protein tyrosine kinase; [PF08263] Leucine rich repeat N-terminal domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PF12799] Leucine Rich repeats (2 copies); [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 150.84 0.6125 133 Mapoly0015s0081 [PF11707] Ribosome 60S biogenesis N-terminal; [PTHR13500] NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1 152.08 0.6633 134 Mapoly0027s0035 [KOG2006] WD40 repeat protein; [PTHR22746] FAMILY NOT NAMED; [PF07064] RIC1 152.81 0.6437 135 Mapoly0005s0119 [PF13414] TPR repeat; [PTHR22904] TPR REPEAT CONTAINING PROTEIN 154.51 0.5306 136 Mapoly0074s0004 [PTHR10652] ADENYLYL CYCLASE-ASSOCIATED PROTEIN; [PF01213] Adenylate cyclase associated (CAP) N terminal; [KOG2675] Adenylate cyclase-associated protein (CAP/Srv2p); [PF08603] Adenylate cyclase associated (CAP) C terminal; [GO:0003779] actin binding; [GO:0007010] cytoskeleton organization 155.68 0.6030 137 Mapoly0053s0089 [GO:0006904] vesicle docking involved in exocytosis; [GO:0016192] vesicle-mediated transport; [PTHR11679] VESICLE PROTEIN SORTING-ASSOCIATED; [KOG1300] Vesicle trafficking protein Sec1; [PF00995] Sec1 family 157.81 0.5534 138 Mapoly0199s0006 [GO:0019901] protein kinase binding; [KOG1674] Cyclin; [PTHR15615] UNCHARACTERIZED; [PF08613] Cyclin; [GO:0000079] regulation of cyclin-dependent protein serine/threonine kinase activity 158.13 0.5887 139 Mapoly0021s0082 [GO:0005524] ATP binding; [PTHR24222] FAMILY NOT NAMED; [GO:0016021] integral to membrane; [PF00664] ABC transporter transmembrane region; [KOG0058] Peptide exporter, ABC superfamily; [GO:0016887] ATPase activity; [GO:0006810] transport; [GO:0055085] transmembrane transport; [GO:0042626] ATPase activity, coupled to transmembrane movement of substances; [PF00005] ABC transporter 160.07 0.6228 140 Mapoly0125s0035 [PTHR23081] RNA POLYMERASE II CTD PHOSPHATASE; [PF00035] Double-stranded RNA binding motif; [PF03031] NLI interacting factor-like phosphatase; [GO:0005515] protein binding; [PTHR23081:SF1] RNA POLYMERASE II CTD PHOSPHATASE 161.07 0.6375 141 Mapoly0013s0059 [GO:0005515] protein binding; [PF02213] GYF domain; [PTHR14445] GRB10 INTERACTING GYF PROTEIN 161.16 0.6488 142 Mapoly0058s0070 [PF00168] C2 domain; [PF00514] Armadillo/beta-catenin-like repeat; [GO:0005515] protein binding; [KOG0166] Karyopherin (importin) alpha; [PTHR23315] BETA CATENIN-RELATED ARMADILLO REPEAT-CONTAINING 161.80 0.5698 143 Mapoly0071s0078 [PF00264] Common central domain of tyrosinase; [PF12142] Polyphenol oxidase middle domain; [GO:0055114] oxidation-reduction process; [PTHR11474] TYROSINASE; [GO:0016491] oxidoreductase activity; [GO:0008152] metabolic process; [GO:0004097] catechol oxidase activity; [PF12143] Protein of unknown function (DUF_B2219) 162.68 0.5229 144 Mapoly0214s0015 [GO:0005524] ATP binding; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [PTHR24349] SERINE/THREONINE-PROTEIN KINASE; [GO:0006468] protein phosphorylation; [KOG0032] Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily; [PF13499] EF-hand domain pair; [GO:0005509] calcium ion binding 164.92 0.5988 145 Mapoly0105s0052 [PTHR32387] FAMILY NOT NAMED; [PF13020] Domain of unknown function (DUF3883); [PTHR32387:SF0] SUBFAMILY NOT NAMED 165.64 0.5955 146 Mapoly0001s0267 [GO:0071203] WASH complex; [PTHR31409:SF0] SUBFAMILY NOT NAMED; [PF14745] WASH complex subunit 7, N-terminal; [KOG3578] Uncharacterized conserved protein; [PF14746] WASH complex subunit 7, C-terminal; [PF14744] WASH complex subunit 7; [PTHR31409] FAMILY NOT NAMED 165.75 0.6443 147 Mapoly0091s0002 [GO:0016020] membrane; [PTHR11119] XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; [GO:0006810] transport; [GO:0055085] transmembrane transport; [KOG1292] Xanthine/uracil transporters; [GO:0005215] transporter activity; [PF00860] Permease family 166.16 0.5716 148 Mapoly0104s0008 - 166.93 0.5623 149 Mapoly0124s0011 [KOG1825] Fry-like conserved proteins; [PF14225] Cell morphogenesis C-terminal; [PTHR12295] UNCHARACTERIZED; [PF14222] Cell morphogenesis N-terminal; [PF14228] Cell morphogenesis central region 167.56 0.6143 150 Mapoly0021s0007 [PTHR11851:SF85] AGR251CP; [3.4.24.56] Insulysin.; [KOG0959] N-arginine dibasic convertase NRD1 and related Zn2+-dependent endopeptidases, insulinase superfamily; [K01408] insulysin [EC:3.4.24.56]; [PTHR11851] METALLOPROTEASE; [PF05193] Peptidase M16 inactive domain; [PF00675] Insulinase (Peptidase family M16) 169.25 0.6162 151 Mapoly0089s0032 [PF04765] Protein of unknown function (DUF616); [PTHR12956] ALKALINE CERAMIDASE-RELATED 170.25 0.6075 152 Mapoly0020s0097 [PF13516] Leucine Rich repeat; [PF08263] Leucine rich repeat N-terminal domain; [GO:0005515] protein binding; [PF00560] Leucine Rich Repeat; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE; [KOG0472] Leucine-rich repeat protein 170.66 0.5712 153 Mapoly0089s0048 - 170.97 0.5908 154 Mapoly0040s0008 [GO:0019867] outer membrane; [PTHR12815] SORTING AND ASSEMBLY MACHINERY (SAM50) PROTEIN; [PF07244] Surface antigen variable number repeat; [PF01103] Surface antigen 171.46 0.6296 155 Mapoly0012s0104 [GO:0031625] ubiquitin protein ligase binding; [GO:0031461] cullin-RING ubiquitin ligase complex; [KOG2166] Cullins; [GO:0006511] ubiquitin-dependent protein catabolic process; [PF10557] Cullin protein neddylation domain; [PTHR11932] CULLIN; [PF00888] Cullin family 171.47 0.5683 156 Mapoly0001s0335 [KOG0978] E3 ubiquitin ligase involved in syntaxin degradation 171.83 0.6219 157 Mapoly0019s0112 - 172.15 0.6274 158 Mapoly0087s0079 [KOG4172] Predicted E3 ubiquitin ligase; [PF13920] Zinc finger, C3HC4 type (RING finger) 172.90 0.5938 159 Mapoly0153s0012 [K07195] exocyst complex component 7; [PF03081] Exo70 exocyst complex subunit; [PTHR12542] EXOCYST COMPLEX PROTEIN EXO70; [GO:0000145] exocyst; [KOG2344] Exocyst component protein and related proteins; [GO:0006887] exocytosis 173.33 0.5830 160 Mapoly0004s0252 [GO:0004843] ubiquitin-specific protease activity; [3.1.2.15] Ubiquitin thiolesterase.; [PTHR24006:SF24] SUBFAMILY NOT NAMED; [PF00443] Ubiquitin carboxyl-terminal hydrolase; [K11835] ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]; [GO:0006511] ubiquitin-dependent protein catabolic process; [PF14836] Ubiquitin-like domain; [PTHR24006] FAMILY NOT NAMED; [PF06337] DUSP domain; [KOG1870] Ubiquitin C-terminal hydrolase 174.21 0.6278 161 Mapoly0060s0082 [PTHR23213] FORMIN-RELATED; [KOG4462] WASP-interacting protein VRP1/WIP, contains WH2 domain 174.51 0.6378 162 Mapoly0224s0004 - 176.89 0.5807 163 Mapoly0013s0023 [GO:0000287] magnesium ion binding; [GO:0003723] RNA binding; [GO:0005524] ATP binding; [PF03483] B3/4 domain; [GO:0005737] cytoplasm; [K01890] phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]; [GO:0004826] phenylalanine-tRNA ligase activity; [PF03484] tRNA synthetase B5 domain; [6.1.1.20] Phenylalanine--tRNA ligase.; [GO:0043039] tRNA aminoacylation; [GO:0006432] phenylalanyl-tRNA aminoacylation; [GO:0000049] tRNA binding; [KOG2472] Phenylalanyl-tRNA synthetase beta subunit; [GO:0004812] aminoacyl-tRNA ligase activity; [PTHR10947] PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47; [PF01409] tRNA synthetases class II core domain (F) 177.12 0.6193 164 Mapoly0094s0018 [PF13855] Leucine rich repeat; [KOG1187] Serine/threonine protein kinase; [PF07714] Protein tyrosine kinase; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF12819] Carbohydrate-binding protein of the ER; [GO:0006468] protein phosphorylation; [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 177.41 0.6216 165 Mapoly0047s0077 [PF13812] Pentatricopeptide repeat domain; [PF01535] PPR repeat; [PTHR24015] FAMILY NOT NAMED; [PF13041] PPR repeat family 183.71 0.6153 166 Mapoly0084s0065 [KOG1339] Aspartyl protease; [PF14543] Xylanase inhibitor N-terminal; [PTHR13683] ASPARTYL PROTEASES; [PF14541] Xylanase inhibitor C-terminal; [GO:0004190] aspartic-type endopeptidase activity; [GO:0006508] proteolysis 184.59 0.6121 167 Mapoly0150s0016 [PF00010] Helix-loop-helix DNA-binding domain; [GO:0046983] protein dimerization activity; [PTHR31945] FAMILY NOT NAMED 184.93 0.5527 168 Mapoly0001s0414 [PF14686] Polysaccharide lyase family 4, domain II; [PTHR32018] FAMILY NOT NAMED; [PF14683] Polysaccharide lyase family 4, domain III; [PF06045] Rhamnogalacturonate lyase family 185.13 0.5648 169 Mapoly0067s0018 [GO:0016020] membrane; [GO:0008375] acetylglucosaminyltransferase activity; [PF02485] Core-2/I-Branching enzyme; [PTHR31042] FAMILY NOT NAMED 185.13 0.5037 170 Mapoly0008s0194 [6.6.1.1] Magnesium chelatase.; [PF02514] CobN/Magnesium Chelatase; [PF11965] Domain of unknown function (DUF3479); [GO:0009058] biosynthetic process; [GO:0016851] magnesium chelatase activity; [PTHR23304] SPOT2-RELATED; [K03403] magnesium chelatase subunit H [EC:6.6.1.1] 186.38 0.5997 171 Mapoly0031s0194 - 186.41 0.5558 172 Mapoly0001s0359 [KOG2286] Exocyst complex subunit SEC6; [GO:0000145] exocyst; [PF06046] Exocyst complex component Sec6; [PTHR21292] EXOCYST COMPLEX COMPONENT SEC6-RELATED; [PTHR21292:SF1] EXOCYST COMPLEX COMPONENT SEC6; [GO:0006887] exocytosis 187.48 0.5371 173 Mapoly0019s0074 [KOG0989] Replication factor C, subunit RFC4; [PF12169] DNA polymerase III subunits gamma and tau domain III; [PTHR11669] REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; [PF13177] DNA polymerase III, delta subunit; [GO:0003887] DNA-directed DNA polymerase activity; [PTHR11669:SF0] SUBFAMILY NOT NAMED 189.42 0.5919 174 Mapoly0097s0043 - 189.78 0.6106 175 Mapoly0089s0014 [PTHR24072:SF73] SUBFAMILY NOT NAMED; [KOG1707] Predicted Ras related/Rac-GTP binding protein; [PF08355] EF hand associated; [GO:0007264] small GTPase mediated signal transduction; [PF08356] EF hand associated; [PTHR24072] RHO FAMILY GTPASE; [GO:0005622] intracellular; [GO:0005525] GTP binding; [PF08477] Miro-like protein 190.32 0.6387 176 Mapoly0011s0174 [KOG2967] Uncharacterized conserved protein; [PTHR13563] RNA (GUANINE-9-) METHYLTRANSFERASE DOMAIN CONTAINING; [PTHR13563:SF6] RNA (GUANINE-9-) METHYLTRANSFERASE DOMAIN CONTAINING 2; [PF01746] tRNA (Guanine-1)-methyltransferase 191.16 0.6094 177 Mapoly0037s0088 [KOG0143] Iron/ascorbate family oxidoreductases; [GO:0055114] oxidation-reduction process; [PF14226] non-haem dioxygenase in morphine synthesis N-terminal; [GO:0016706] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; [PTHR10209] OXIDOREDUCTASE, 2OG-FE(II) OXYGENASE FAMILY PROTEIN; [GO:0016491] oxidoreductase activity; [PF03171] 2OG-Fe(II) oxygenase superfamily 192.24 0.5266 178 Mapoly0010s0191 [PF04055] Radical SAM superfamily; [PTHR13930] RSAFD1-RELATED; [PF00258] Flavodoxin; [PF08608] Wyosine base formation; [GO:0016491] oxidoreductase activity; [PTHR13930:SF0] SUBFAMILY NOT NAMED; [GO:0003824] catalytic activity; [GO:0051536] iron-sulfur cluster binding; [KOG1160] Fe-S oxidoreductase; [GO:0010181] FMN binding 193.00 0.6349 179 Mapoly0266s0001 [PF00264] Common central domain of tyrosinase; [PTHR11474] TYROSINASE; [GO:0016491] oxidoreductase activity; [GO:0008152] metabolic process 194.65 0.5014 180 Mapoly0157s0018 [GO:0000287] magnesium ion binding; [GO:0005737] cytoplasm; [PTHR21403:SF1] ATP PHOSPHORIBOSYLTRANSFERASE (ATP-PRTASE); [GO:0000105] histidine biosynthetic process; [K00765] ATP phosphoribosyltransferase [EC:2.4.2.17]; [PF01634] ATP phosphoribosyltransferase; [PF08029] HisG, C-terminal domain; [GO:0003879] ATP phosphoribosyltransferase activity; [2.4.2.17] ATP phosphoribosyltransferase.; [KOG2831] ATP phosphoribosyltransferase; [PTHR21403] ATP PHOSPHORIBOSYLTRANSFERASE (ATP-PRTASE) 197.13 0.6153 181 Mapoly0026s0062 [PF00225] Kinesin motor domain; [GO:0005524] ATP binding; [PTHR24115] FAMILY NOT NAMED; [PTHR24115:SF81] SUBFAMILY NOT NAMED; [KOG0242] Kinesin-like protein; [GO:0005871] kinesin complex; [GO:0007018] microtubule-based movement; [GO:0008017] microtubule binding; [GO:0003777] microtubule motor activity 197.27 0.5535 182 Mapoly0061s0099 [KOG1401] Acetylornithine aminotransferase; [K00833] adenosylmethionine-8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]; [PTHR11986] AMINOTRANSFERASE CLASS III; [2.6.1.62] Adenosylmethionine--8-amino-7-oxononanoate transaminase.; [GO:0030170] pyridoxal phosphate binding; [PF13500] AAA domain; [PTHR11986:SF8] ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE; [GO:0008483] transaminase activity; [PF00202] Aminotransferase class-III 199.04 0.5890 183 Mapoly0101s0065 [PF12330] Domain of unknown function (DUF3635); [PTHR24419] INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE; [KOG2464] Serine/threonine kinase (haspin family) 200.27 0.6105 184 Mapoly0106s0026 [KOG1830] Wiskott Aldrich syndrome proteins; [GO:0005856] cytoskeleton; [GO:0030036] actin cytoskeleton organization; [PTHR12902] WASP-1 200.37 0.6114 185 Mapoly0102s0039 [GO:0005524] ATP binding; [KOG0576] Mitogen-activated protein kinase kinase kinase kinase (MAP4K), germinal center kinase family; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24361] MITOGEN-ACTIVATED KINASE KINASE KINASE 200.78 0.6379 186 Mapoly0055s0021 - 200.98 0.5605 187 Mapoly0102s0020 [GO:0005524] ATP binding; [PTHR19211] ATP-BINDING TRANSPORT PROTEIN-RELATED; [GO:0016887] ATPase activity; [KOG0062] ATPase component of ABC transporters with duplicated ATPase domains/Translation elongation factor EF-3b; [K06158] ATP-binding cassette, sub-family F, member 3; [PF12848] ABC transporter; [PF00005] ABC transporter 201.85 0.6398 188 Mapoly0006s0083 [3.4.24.-] Metalloendopeptidases.; [GO:0005524] ATP binding; [GO:0004222] metalloendopeptidase activity; [K03798] cell division protease FtsH [EC:3.4.24.-]; [KOG0731] AAA+-type ATPase containing the peptidase M41 domain; [PF01434] Peptidase family M41; [PTHR23076] METALLOPROTEASE M41 FTSH; [PF00004] ATPase family associated with various cellular activities (AAA); [GO:0006508] proteolysis 203.19 0.6312 189 Mapoly0072s0100 [PF13855] Leucine rich repeat; [GO:0005524] ATP binding; [KOG1187] Serine/threonine protein kinase; [PF13516] Leucine Rich repeat; [PF00069] Protein kinase domain; [GO:0005515] protein binding; [GO:0004672] protein kinase activity; [PF00560] Leucine Rich Repeat; [GO:0006468] protein phosphorylation; [PF12799] Leucine Rich repeats (2 copies); [PTHR24420] LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE 204.32 0.5800 190 Mapoly0125s0016 [GO:0005737] cytoplasm; [GO:0009058] biosynthetic process; [K01892] histidyl-tRNA synthetase [EC:6.1.1.21]; [GO:0016841] ammonia-lyase activity; [PF00221] Aromatic amino acid lyase; [PTHR11476:SF1] HISTIDYL-TRNA SYNTHETASE; [PF03129] Anticodon binding domain; [PTHR11476] HISTIDYL-TRNA SYNTHETASE; [PF13393] Histidyl-tRNA synthetase; [KOG1936] Histidyl-tRNA synthetase; [6.1.1.21] Histidine--tRNA ligase. 204.67 0.6514 191 Mapoly0136s0027 - 205.27 0.5719 192 Mapoly0009s0042 [KOG1985] Vesicle coat complex COPII, subunit SEC24/subunit SFB2; [PF04815] Sec23/Sec24 helical domain; [GO:0008270] zinc ion binding; [PTHR13803:SF4] gb def: SED5-binding protein 3 (SEC24-related protein 3) (Lethal with SEC13 protein 1); [PF08033] Sec23/Sec24 beta-sandwich domain; [PF04811] Sec23/Sec24 trunk domain; [GO:0006886] intracellular protein transport; [K14007] protein transport protein SEC24; [PF04810] Sec23/Sec24 zinc finger; [GO:0030127] COPII vesicle coat; [PTHR13803] SEC24-RELATED PROTEIN; [GO:0006888] ER to Golgi vesicle-mediated transport 205.71 0.6103 193 Mapoly0065s0074 [GO:0016876] ligase activity, forming aminoacyl-tRNA and related compounds; [GO:0005524] ATP binding; [PF00587] tRNA synthetase class II core domain (G, H, P, S and T); [GO:0000166] nucleotide binding; [GO:0043039] tRNA aminoacylation; [PF07973] Threonyl and Alanyl tRNA synthetase second additional domain; [K01868] threonyl-tRNA synthetase [EC:6.1.1.3]; [PTHR11451] TRNA SYNTHETASE-RELATED; [6.1.1.3] Threonine--tRNA ligase.; [PF03129] Anticodon binding domain; [KOG1637] Threonyl-tRNA synthetase; [GO:0006418] tRNA aminoacylation for protein translation; [PF02824] TGS domain; [GO:0004812] aminoacyl-tRNA ligase activity 210.56 0.6149 194 Mapoly0001s0171 - 210.60 0.5744 195 Mapoly0033s0138 [PF10250] GDP-fucose protein O-fucosyltransferase; [PTHR31741] FAMILY NOT NAMED 211.37 0.5828 196 Mapoly0202s0016 - 214.80 0.5023 197 Mapoly0076s0069 [PF00657] GDSL-like Lipase/Acylhydrolase; [PTHR22835] ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN; [GO:0016788] hydrolase activity, acting on ester bonds; [GO:0006629] lipid metabolic process 215.96 0.5804 198 Mapoly0160s0010 [GO:0005524] ATP binding; [KOG0588] Serine/threonine protein kinase; [PF00069] Protein kinase domain; [GO:0004672] protein kinase activity; [GO:0006468] protein phosphorylation; [PTHR24343:SF15] CARBON CATABOLITE-DEREPRESSING PROTEIN KINASE; [PF02149] Kinase associated domain 1; [PTHR24343] SERINE/THREONINE KINASE 216.56 0.6324 199 Mapoly0066s0021 [KOG1884] Uncharacterized conserved protein; [PF14649] Spatacsin C-terminus; [PTHR13650] UNCHARACTERIZED 217.03 0.6172 200 Mapoly0124s0035 [PF00933] Glycosyl hydrolase family 3 N terminal domain; [GO:0004553] hydrolase activity, hydrolyzing O-glycosyl compounds; [GO:0005975] carbohydrate metabolic process; [PTHR30620] PERIPLASMIC BETA-GLUCOSIDASE-RELATED; [PF01915] Glycosyl hydrolase family 3 C-terminal domain 217.17 0.4849